Bilberry may be the potential target used by conventional medicine in the future for the treatment of cancer with no side effects, according to studies.
Cancer is a class of medical condition characterized by cell growth irregularly due to the alternation of cell DNA.
Most cases of cancers begin in the cells on the surface of the inner lining of the body tissues and do not cause any symptoms at the early stage.
However, invasive cancer at the advanced stage can cause localized symptoms accompanied by the cancer general symptoms and its cells can also travel a distance away from the original site to infect other healthy tissues and organs, leading secondary metastasis.
According to the US government statistics, the prevalent risk of cancer development is 439.2 per 100,000 men and women per year based on 2011–2015 cases, causing the death of 163.5 per 100,000 men and women per year.
The exact causes of cancer are unknown. Epidemiologically, certain factors are associated with the prevalent risk of cancer including age, ethnicity, long-term exposure to toxic chemicals, and genetic preposition.
Some researchers suggested that the widespread obesity in the Western world, particularly in North America may have a strong impact on the increased risk of cancer. According to statistics, over 68% of American are either overweight or obese.
Dr. Giovanni De Pergola, the lead scientist in the assessment obese in cancer risk said, "The number of cancer cases caused by being obese is estimated to be 20% with the increased risk of malignancies being influenced by diet, weight change, and body fat distribution together with physical activity".
And, "Reports from the International Agency for Research into Cancer and the World Cancer Research Fund (WCRF) have shown that the strongest evidence exists for an association of obesity with the following cancer types: endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal, whereas the less common malignancies, are leukemia, non-Hodgkin's lymphoma, multiple myeloma, malignant melanoma, and thyroid tumors".
The results strongly clearly suggested if you are obese, your risk of cancer is increased substantially compared to non-obese individuals.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Scientists on finding a natural and potential compound for the treatment of cancer examined the anthocyanins anticancer activity in rodent models of cancer in-vitro and in- vivo.
Bilberry anthocyanins as chemopreventive agents showed a significant effect in 25 colorectal cancer patients. The result has opened a new window of opportunity in translating the findings from laboratory to clinic.
According to the study, anthocyanins treated cancer cells by stimulating the production of the tumor suppressor genes.
Application of anthocyanins also inhibited the cancer cell proliferation through activating the protein associated with cell death programming.
Dr. Sehitoglu MH and colleagues wrote in the final report, "his review we bring to limelight how anthocyanins induced apoptosis in cancer cells via activation of extrinsic and intrinsic pathways".
In order to reveal additional information about bilberry anti-cancer effects, researchers investigated the anthocyanins (A(V.uli)) bioactivity on suppressing cancer cells.
Malvidin, the major compound isolated from A(V.uli) at a dose-dependent inhibited cancer cell proliferation with an IC(50) (50% inhibitory concentration) value of 50 µg/ml.
The findings strongly reconfirmed the anti-cancer effects of anthocyanin extraction. A(V.uli) from the bilberry.
Taken altogether, bilberry processed a high amount of bioactive compounds such as delphinidin, cyanidin, petunidin, peonidin, and malvidin may be considered a functional food for the prevention and treatment of cancer with no side effects, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anthocyanins: targeting of signaling networks in cancer cells by Sehitoglu MH1, Farooqi AA, Qureshi MZ, Butt G, Aras A. (PubMed)
(2) Anthocyanins extracted from Chinese blueberry (Vaccinium uliginosum L.) and its anticancer effects on DLD-1 and COLO205 cells by Zu XY1, Zhang ZY, Zhang XW, Yoshioka M, Yang YN, Li J. (PubMed)
(3) Obesity as a Major Risk Factor for Cancer by Giovanni De Pergola* and Franco Silvestris. (PMC)
Sunday, April 21, 2019
Phytochemical 3,3'-Diindolylmethane, The Potential Melanoma Inhibitor, According to Studies
3,3'-Diindolylmethane may be the next bioactive compound for the treatment of melanoma with no side effects, according to studies.
Melanoma is skin cancer caused by the alternation of melanocytes DNA in the skin pigment, leading to the formation of moles that change in the color, size or shape on the skin.
Most cases of melanoma start in the melanocytes or pigment-producing cells in the outer layer of the skin. However, at the later stage, the cancer cells can travel through the circulation of blood and fluids to infect other healthy cells and tissue, leading to secondary metastasis.
The liver, lungs, bones, and brain are most often affected by melanoma metastases.
According to statistic, the risk of melanoma is largely depended on the race. the lifetime risk of getting melanoma is about 2.5% (1 in 40) for whites, 0.1% (1 in 1,000) for blacks, and 0.5% (1 in 200) for Hispanics.
The 5 years survival rate of melanoma is closed to 100% if the disease is diagnosed in the localized stages.
In the US, every year, approximately 96,480 new melanomas are diagnosed, leading to the death of 7,000 people.
In North America, most cases of melanoma are associated with UVB exposure, causing the alteration of the cell DNA.
Dr. S A Oliveria, the lead scientist said, "Sun-sensitive phenotypes and reported sunburn were associated with an increased risk of melanoma" and "intense sun exposure is causal for melanoma in those prone to sunburn".
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
Researchers on finding a natural compound for the treatment of melanoma compared the effects of
kaempferol (Kem), genistein (Gen), and 3'3-diindolylmethane (DIM) on melanoma cell viability.
Treatment of A375SM melanoma cells with the tested phytochemicals resulted in inhibition of cell growth.
DIM exerted the strong inhibition against the A375SM melanoma cells by increasing the tumor suppressive gene expression, p21 and decreasing the gene expression associated with the cancer cell proliferation and survival.
Injection of DIM and other tested phytochemical also induced the expression of pro-apoptotic pathways against the tested cancer cell line and deactivated the anti-apoptotic pathways.
Furthermore, DIM and tested phytochemical also enhanced the activity of ROS in the induction of cytotoxicity without causing harm to the healthy cells.
Dr. Heo JR and colleagues said, "These results indicate that phytochemicals (kaempferol (Kem), genistein (Gen), and 3'3-diindolylmethane (DIM)) are potentially useful in treatments for melanoma due to their ability to inhibit melanoma cell growth and division".
Taken altogether, 3,3'-Diindolylmethane may be considered a supplement for the prevention and combined with primary medicine for the treatment of melanoma, pending to the confirmation of large sample size and multicenter human study.
Injection of DIM in a form of supplement should be taken with exceptional care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells by Heo JR1, Lee GA1, Kim GS1, Hwang KA1, Choi KC. (PubMed)
(2) Novel 3,3'-diindolylmethane derivatives: synthesis and cytotoxicity, structural characterization in solid state by Maciejewska D1, Rasztawicka M, Wolska I, Anuszewska E, Gruber B. (PubMed)
(3) Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate by Julia A Newton-Bishop, Yu-Mei Chang, Faye Elliott, May Chan, Susan Leake, Birute Karpavicius, Sue Haynes, Elaine Fitzgibbon, Kairen Kukalizch, Juliette Randerson-Moor, David E Elder,* D Timothy Bishop, and Jennifer H Barrett. (PMC)
Melanoma is skin cancer caused by the alternation of melanocytes DNA in the skin pigment, leading to the formation of moles that change in the color, size or shape on the skin.
Most cases of melanoma start in the melanocytes or pigment-producing cells in the outer layer of the skin. However, at the later stage, the cancer cells can travel through the circulation of blood and fluids to infect other healthy cells and tissue, leading to secondary metastasis.
The liver, lungs, bones, and brain are most often affected by melanoma metastases.
According to statistic, the risk of melanoma is largely depended on the race. the lifetime risk of getting melanoma is about 2.5% (1 in 40) for whites, 0.1% (1 in 1,000) for blacks, and 0.5% (1 in 200) for Hispanics.
The 5 years survival rate of melanoma is closed to 100% if the disease is diagnosed in the localized stages.
In the US, every year, approximately 96,480 new melanomas are diagnosed, leading to the death of 7,000 people.
In North America, most cases of melanoma are associated with UVB exposure, causing the alteration of the cell DNA.
Dr. S A Oliveria, the lead scientist said, "Sun-sensitive phenotypes and reported sunburn were associated with an increased risk of melanoma" and "intense sun exposure is causal for melanoma in those prone to sunburn".
3,3'-Diindolylmethane or DIM are phytochemicals derived from the digestion of indole-3-carbinol, belonging to the group of Indoles, found abundantly in broccoli, Brussels sprouts, cabbage, and kale, etc.
Researchers on finding a natural compound for the treatment of melanoma compared the effects of
kaempferol (Kem), genistein (Gen), and 3'3-diindolylmethane (DIM) on melanoma cell viability.
Treatment of A375SM melanoma cells with the tested phytochemicals resulted in inhibition of cell growth.
DIM exerted the strong inhibition against the A375SM melanoma cells by increasing the tumor suppressive gene expression, p21 and decreasing the gene expression associated with the cancer cell proliferation and survival.
Injection of DIM and other tested phytochemical also induced the expression of pro-apoptotic pathways against the tested cancer cell line and deactivated the anti-apoptotic pathways.
Furthermore, DIM and tested phytochemical also enhanced the activity of ROS in the induction of cytotoxicity without causing harm to the healthy cells.
Dr. Heo JR and colleagues said, "These results indicate that phytochemicals (kaempferol (Kem), genistein (Gen), and 3'3-diindolylmethane (DIM)) are potentially useful in treatments for melanoma due to their ability to inhibit melanoma cell growth and division".
Taken altogether, 3,3'-Diindolylmethane may be considered a supplement for the prevention and combined with primary medicine for the treatment of melanoma, pending to the confirmation of large sample size and multicenter human study.
Injection of DIM in a form of supplement should be taken with exceptional care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells by Heo JR1, Lee GA1, Kim GS1, Hwang KA1, Choi KC. (PubMed)
(2) Novel 3,3'-diindolylmethane derivatives: synthesis and cytotoxicity, structural characterization in solid state by Maciejewska D1, Rasztawicka M, Wolska I, Anuszewska E, Gruber B. (PubMed)
(3) Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate by Julia A Newton-Bishop, Yu-Mei Chang, Faye Elliott, May Chan, Susan Leake, Birute Karpavicius, Sue Haynes, Elaine Fitzgibbon, Kairen Kukalizch, Juliette Randerson-Moor, David E Elder,* D Timothy Bishop, and Jennifer H Barrett. (PMC)
Saturday, April 20, 2019
Curcumin, the Single Bioactive Compound Which Processes Cardioprotective Property Against Heart Disease, Scientists Say
Scientists may have found a kitchen bioactive compound which processes cardio-protective properties, according to studies.
Cardioprotection is an action that contributes to the protection of heart integrity against damage or injury.
In other words, cardioprotection is a process in which substances or medicines are used including an herbal remedy to protect heart muscle tissues against ischemic insult and deoxygenation injury.
Cardiovascular diseases (CVD) are a class of conditions associated with the dysfunction of the arteries and heart.
Coronary artery disease caused by narrowing of the arteries, heart attack, abnormal heart rhythms, or arrhythmias and stroke are the most common types of cardiovascular diseases found in the Western world.
Most common symptoms of CVD include persistent fatigue, shortness of breath, irregular heartbeat, chest pain, and fainting.
If you have some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the CVD possibility.
The exact causes of cardiovascular diseases are unidentified. However, according to epidemiological studies, the most prevalent factors include aging, smoking. lack of exercise. unhealthy diet. obesity. high blood pressure and cholesterol, and family history.
Out of many risk factors, an unhealthy lifestyle is one of the major risk factors that cause the onset of CVD, some researchers suggested.
Dr. Haskell WL in the investigation of cardiovascular disease prevention and lifestyle interventions
said, "While heredity can be a major factor for some people, their personal health habits and environmental/cultural exposure are more important factors".
And, "Not smoking, being physically active, eating a heart-healthy diet, staying reasonably lean, and avoiding major stress and depression are the major components of an effective CVD prevention program. For people at high risk of CVD, medications frequently need to be added to a healthy lifestyle to minimize their risk of a heart attack or stroke, particularly in persons with conditions such as hypertension, hypercholesterolemia, or hyperglycemia. Maintaining an effective CVD prevention program in technologically advanced societies cannot be achieved by many high-risk persons without effective and sustained support from a well-organized health care system".
The results strongly suggested by lifestyle change has a strong implication in the prevention of the CVD.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potent compound which processes cardioprotective effects, researchers investigated the cardioprotective effect of curcumin in NE-induced cardiac apoptosis. According to the tested assays, curcumin protected the cardiomyocytes against apoptosis significantly.
Furthermore, injection of curcumin also reverted to cardiomyocytes damage back to the normal physiological state.
In other words, curcumin protected the integrity of heart muscle cells against Norepinephrine (NE) in the induction of the onset of cardiomyopathy and heart failure.
Dr. Manghani C, the lead scientist said, "curcumin has the potential to act as a therapeutic agent for the attenuation of NE-induced cardiac cell death and modulation of apoptosis in H9c2 cardiomyocytes".
Taken altogether, turmeric may be considered a cardioprotective supplement for the prevention and treatment of cardiovascular disease, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cardioprotective potential of curcumin against norepinephrine-induced cell death: a microscopic study by Manghani C1, Gupta A1, Tripathi V1, Rani V. (PubMed)
(2) Cardioprotective actions of curcumin on the pathogenic NFAT/COX-2/prostaglandin E2 pathway induced during Trypanosoma cruzi infection by Hernández M1, Wicz S1, Corral RS. (PubMed)
(3) Cardiovascular disease prevention and lifestyle interventions: effectiveness and efficacy by Haskell WL. (PubMed)
Cardioprotection is an action that contributes to the protection of heart integrity against damage or injury.
In other words, cardioprotection is a process in which substances or medicines are used including an herbal remedy to protect heart muscle tissues against ischemic insult and deoxygenation injury.
Cardiovascular diseases (CVD) are a class of conditions associated with the dysfunction of the arteries and heart.
Coronary artery disease caused by narrowing of the arteries, heart attack, abnormal heart rhythms, or arrhythmias and stroke are the most common types of cardiovascular diseases found in the Western world.
Most common symptoms of CVD include persistent fatigue, shortness of breath, irregular heartbeat, chest pain, and fainting.
If you have some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the CVD possibility.
The exact causes of cardiovascular diseases are unidentified. However, according to epidemiological studies, the most prevalent factors include aging, smoking. lack of exercise. unhealthy diet. obesity. high blood pressure and cholesterol, and family history.
Out of many risk factors, an unhealthy lifestyle is one of the major risk factors that cause the onset of CVD, some researchers suggested.
Dr. Haskell WL in the investigation of cardiovascular disease prevention and lifestyle interventions
said, "While heredity can be a major factor for some people, their personal health habits and environmental/cultural exposure are more important factors".
And, "Not smoking, being physically active, eating a heart-healthy diet, staying reasonably lean, and avoiding major stress and depression are the major components of an effective CVD prevention program. For people at high risk of CVD, medications frequently need to be added to a healthy lifestyle to minimize their risk of a heart attack or stroke, particularly in persons with conditions such as hypertension, hypercholesterolemia, or hyperglycemia. Maintaining an effective CVD prevention program in technologically advanced societies cannot be achieved by many high-risk persons without effective and sustained support from a well-organized health care system".
The results strongly suggested by lifestyle change has a strong implication in the prevention of the CVD.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potent compound which processes cardioprotective effects, researchers investigated the cardioprotective effect of curcumin in NE-induced cardiac apoptosis. According to the tested assays, curcumin protected the cardiomyocytes against apoptosis significantly.
Furthermore, injection of curcumin also reverted to cardiomyocytes damage back to the normal physiological state.
In other words, curcumin protected the integrity of heart muscle cells against Norepinephrine (NE) in the induction of the onset of cardiomyopathy and heart failure.
Dr. Manghani C, the lead scientist said, "curcumin has the potential to act as a therapeutic agent for the attenuation of NE-induced cardiac cell death and modulation of apoptosis in H9c2 cardiomyocytes".
Taken altogether, turmeric may be considered a cardioprotective supplement for the prevention and treatment of cardiovascular disease, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cardioprotective potential of curcumin against norepinephrine-induced cell death: a microscopic study by Manghani C1, Gupta A1, Tripathi V1, Rani V. (PubMed)
(2) Cardioprotective actions of curcumin on the pathogenic NFAT/COX-2/prostaglandin E2 pathway induced during Trypanosoma cruzi infection by Hernández M1, Wicz S1, Corral RS. (PubMed)
(3) Cardiovascular disease prevention and lifestyle interventions: effectiveness and efficacy by Haskell WL. (PubMed)
Ginger, the Herbal Remedy Which Promotes Weight Loss
On seeking natural therapy with no side effects, scientists may have a vegetable in the induction of weight loss, according to studies.
Weight loss is a process that intentionally reduces the total body mass, through the decrease of fluid, body fat or adipose tissue or lean mass.
Due to the widespread obesity in North America (over 68% of the US population is either overweight or obese), many weight loss products were created by manufacturers. The weight loss products is a 66 billion business in the US, according to the statistic provided by the Marketdata LLC research firm. And the business continues to grow at a rapid rate.
Is the weight loss products work? I don't think so. Otherwise, the percentage of the overweight population in the US should be decreased substantially.
In other words, all weight loss products may have a complex structure or a long-term commitment before the results can be seen.
The National Institutes of Health wrote, "You might be surprised to learn that makers of weight-loss supplements rarely carry out studies in people to find out whether their product works and is safe. And when studies are done, they usually involve only small numbers of people who take the supplement for just a few weeks or months. To know whether a weight-loss supplement can help people lose weight safely and keep it off, larger groups of people need to be studied for a longer time.".
In short, most weight products are buy-at your own-risk products.
In fact, everyone knows, the proven ways to lose weight are eating healthful foods, cutting calories, and being physically active.
Dr. Catherine M. Champagne and colleagues in the investigation of healthy diets and weight loss, wrote, "Increased intake of fruits and vegetables was associated with weight loss in Phases I and II: 0.29 kg per 6-months (p<0.0001) and 0.04 kg per 6-months (p=0.0062), respectively, per 1-serving increase. Substitution of carbohydrates for fat and protein for carbohydrates were associated with weight loss during both phases".
And, "Increasing dairy intake was associated with significant weight loss during Phase II (−0.17 kg per 6-months per 1-serving increase, p=0.0002), but not in Phase I. Dietary fiber revealed no significant findings".
The results strongly suggested that if you want to lose weight, you better follow a healthy diet with an increased intake of fruits and vegetables.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a herbal remedy that has potential in stimulating weight loss examined the dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles among overweight women.
The randomized double-blind placebo-controlled clinical trial included 50 overweight women satisfied the criteria and guidelines.
Selected candidates were randomly divided into 2 groups. Group A received dietary supplements containing 125 mg green tea, 25 mg capsaicin, and 50 mg ginger extracts (n = 25) group B received placebos (n = 25) twice with lunch and twice with dinner daily for 8 weeks.
Supplement treatment groups showed a significant decrease in weight and body mass index compared to the control.
Women who received the supplement exerted a strong improvement on metabolic profiles including the decreased serum insulin concentrations, insulin resistance (-0.5 ± 0.8 vs. -0.05 ± 0.6, p = 0.01), and increased insulin sensitivity, compared to control.
Futhermore, the antioxidant enzymes produced by the host in the supplement group also was enhanced compared to control.
The results indicated that daily intake of the supplement may have a positive impact on inducing weight loss through improving the body metabolism and antioxidant activity.
Dr, Taghizadeh M and colleagues wrote in the final report, "taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma GSH levels".
In order to reveal more information about using ginger to lose weight, researchers investigated the effect of ginger intake on weight loss, glycemic control, and lipid profiles among overweight and obese subjects by reaching the medical literature online.
The selection of the quality of the studies is based on guidelines of the Cochrane risk of bias tool.
According to the 14 studies with 473 subjects included in the meta-analysis, supplementation with ginger significantly decreased body weight (BW), waist-to-hip ratio (WHR), the hip ratio (HR), fasting glucose, compared to placebo.
Moreover, decreased insulin resistance and significantly increased HDL-cholesterol levels were also observed in the ginger treatment groups.
Surprisingly, ginger supplement showed no effect body mass index (BMI), insulin, triglycerides, total- and LDL-cholesterol.
Dr.Maharlouei N, the lead scientist after taking into account co and confounders said, "Overall, the current meta-analysis demonstrated that ginger intake reduced BW, WHR, HR, fasting glucose and HOMA-IR, and increased HDL-cholesterol, but did not affect insulin, BMI, triglycerides, total- and LDL-cholesterol levels".
Taken altogether, ginger used alone or combined with other supplements may be considered a functional remedy for inducing weight loss in overweight and obese population, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Dietary Supplements Containing Green Tea, Capsaicin and GingerExtracts on Weight Loss and Metabolic Profiles in Overweight Women: A Randomized Double-Blind Placebo-Controlled Clinical Trial by Taghizadeh M1, Farzin N, Taheri S, Mahlouji M, Akbari H, Karamali F, Asemi Z. (PubMed)
(2) The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials by Maharlouei N1, Tabrizi R2, Lankarani KB1, Rezaianzadeh A3, Akbari M2, Kolahdooz F4, Rahimi M5, Keneshlou F6, Asemi Z7. (PubMed)
(3) Dietary intakes associated with successful weight loss and maintenance during the Weight Loss Maintenance Trial by Catherine M. Champagne, PhD, RD, LDN, FADA, Professor-Research, Stephanie T Broyles, PhD, Assistant Professor, Laura D. Moran, MS, RD, LDN, Clinical Dietitian, Katherine C. Cash, RD, LDN, Research Dietitian/Interventionist, Erma J. Levy, MPH, RD, Research Dietitian/Interventionist, Pao-Hwa Lin, PhD, Associate Research Professor, Bryan C. Batch, MD, Lillian F. Lien, MD, Medical Director, Duke Inpatient Diabetes Management, Assistant Professor, Department of Medicine, Kristine L. Funk, MS, RD, Research Associate III, Arlene Dalcin, RD, LDN, Research Associate, Catherine Loria, PhD, MS, MA, FAHA, Nutritional Epidemiologist, and Valerie H. Myers, PhD. (PMC)
Weight loss is a process that intentionally reduces the total body mass, through the decrease of fluid, body fat or adipose tissue or lean mass.
Due to the widespread obesity in North America (over 68% of the US population is either overweight or obese), many weight loss products were created by manufacturers. The weight loss products is a 66 billion business in the US, according to the statistic provided by the Marketdata LLC research firm. And the business continues to grow at a rapid rate.
Is the weight loss products work? I don't think so. Otherwise, the percentage of the overweight population in the US should be decreased substantially.
In other words, all weight loss products may have a complex structure or a long-term commitment before the results can be seen.
The National Institutes of Health wrote, "You might be surprised to learn that makers of weight-loss supplements rarely carry out studies in people to find out whether their product works and is safe. And when studies are done, they usually involve only small numbers of people who take the supplement for just a few weeks or months. To know whether a weight-loss supplement can help people lose weight safely and keep it off, larger groups of people need to be studied for a longer time.".
In short, most weight products are buy-at your own-risk products.
In fact, everyone knows, the proven ways to lose weight are eating healthful foods, cutting calories, and being physically active.
Dr. Catherine M. Champagne and colleagues in the investigation of healthy diets and weight loss, wrote, "Increased intake of fruits and vegetables was associated with weight loss in Phases I and II: 0.29 kg per 6-months (p<0.0001) and 0.04 kg per 6-months (p=0.0062), respectively, per 1-serving increase. Substitution of carbohydrates for fat and protein for carbohydrates were associated with weight loss during both phases".
And, "Increasing dairy intake was associated with significant weight loss during Phase II (−0.17 kg per 6-months per 1-serving increase, p=0.0002), but not in Phase I. Dietary fiber revealed no significant findings".
The results strongly suggested that if you want to lose weight, you better follow a healthy diet with an increased intake of fruits and vegetables.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a herbal remedy that has potential in stimulating weight loss examined the dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles among overweight women.
The randomized double-blind placebo-controlled clinical trial included 50 overweight women satisfied the criteria and guidelines.
Selected candidates were randomly divided into 2 groups. Group A received dietary supplements containing 125 mg green tea, 25 mg capsaicin, and 50 mg ginger extracts (n = 25) group B received placebos (n = 25) twice with lunch and twice with dinner daily for 8 weeks.
Supplement treatment groups showed a significant decrease in weight and body mass index compared to the control.
Women who received the supplement exerted a strong improvement on metabolic profiles including the decreased serum insulin concentrations, insulin resistance (-0.5 ± 0.8 vs. -0.05 ± 0.6, p = 0.01), and increased insulin sensitivity, compared to control.
Futhermore, the antioxidant enzymes produced by the host in the supplement group also was enhanced compared to control.
The results indicated that daily intake of the supplement may have a positive impact on inducing weight loss through improving the body metabolism and antioxidant activity.
Dr, Taghizadeh M and colleagues wrote in the final report, "taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma GSH levels".
In order to reveal more information about using ginger to lose weight, researchers investigated the effect of ginger intake on weight loss, glycemic control, and lipid profiles among overweight and obese subjects by reaching the medical literature online.
The selection of the quality of the studies is based on guidelines of the Cochrane risk of bias tool.
According to the 14 studies with 473 subjects included in the meta-analysis, supplementation with ginger significantly decreased body weight (BW), waist-to-hip ratio (WHR), the hip ratio (HR), fasting glucose, compared to placebo.
Moreover, decreased insulin resistance and significantly increased HDL-cholesterol levels were also observed in the ginger treatment groups.
Surprisingly, ginger supplement showed no effect body mass index (BMI), insulin, triglycerides, total- and LDL-cholesterol.
Dr.Maharlouei N, the lead scientist after taking into account co and confounders said, "Overall, the current meta-analysis demonstrated that ginger intake reduced BW, WHR, HR, fasting glucose and HOMA-IR, and increased HDL-cholesterol, but did not affect insulin, BMI, triglycerides, total- and LDL-cholesterol levels".
Taken altogether, ginger used alone or combined with other supplements may be considered a functional remedy for inducing weight loss in overweight and obese population, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Dietary Supplements Containing Green Tea, Capsaicin and GingerExtracts on Weight Loss and Metabolic Profiles in Overweight Women: A Randomized Double-Blind Placebo-Controlled Clinical Trial by Taghizadeh M1, Farzin N, Taheri S, Mahlouji M, Akbari H, Karamali F, Asemi Z. (PubMed)
(2) The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials by Maharlouei N1, Tabrizi R2, Lankarani KB1, Rezaianzadeh A3, Akbari M2, Kolahdooz F4, Rahimi M5, Keneshlou F6, Asemi Z7. (PubMed)
(3) Dietary intakes associated with successful weight loss and maintenance during the Weight Loss Maintenance Trial by Catherine M. Champagne, PhD, RD, LDN, FADA, Professor-Research, Stephanie T Broyles, PhD, Assistant Professor, Laura D. Moran, MS, RD, LDN, Clinical Dietitian, Katherine C. Cash, RD, LDN, Research Dietitian/Interventionist, Erma J. Levy, MPH, RD, Research Dietitian/Interventionist, Pao-Hwa Lin, PhD, Associate Research Professor, Bryan C. Batch, MD, Lillian F. Lien, MD, Medical Director, Duke Inpatient Diabetes Management, Assistant Professor, Department of Medicine, Kristine L. Funk, MS, RD, Research Associate III, Arlene Dalcin, RD, LDN, Research Associate, Catherine Loria, PhD, MS, MA, FAHA, Nutritional Epidemiologist, and Valerie H. Myers, PhD. (PMC)
Friday, April 19, 2019
Herbal Butterbur, Exhibits Cytotoxic Effects Against Cancers Cells
Scientists may have found a medicinal remedy for the prevention and treatment of cancer with no side effects, according to studies.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, due to change of cellular DNA.
Most cases of cancer start in the cells on the surface of the inner lining of tissue of the organ. At the 0 stage, due to the very small size of the tumor, most patient so not experience any symptoms.
However, at the later stage of the tumor progression, if undetected, the large size of the tumor can suppress and break the nearby small blood vessel, leading to internal bleeding and severe if the tumor also suppresses the nearby nerve cells.
Primary cancer cells at this advanced stage can also travel a distance away from the original site to affect other healthy tissue and organs, leading to secondary metastasis.
Symptoms of cancer at this stage are totally depended on the affected area, including vomiting blood in oral and lung cancers blood in the urine in bladder cancer. hoarseness in throat cancer. ... Persistent lumps in the breast and lymph cancer and indigestion or difficulty swallowing in digestive related cancers.
Researchers do not know the exact causes of cancers, but they do know, according to epidemiological studies that age, alcohol cancer, chronic Inflammation, genetic proposition, unhealthy diet, change of hormones use of immunosuppression, infectious agents, obesity, exposure to radiation and sunlight, use of tobacco are most common risk factors associated with the onset of some specific cancers.
Some researchers in the investigation of weakened immune function in risk of cancer suggested people with a weakened immune system lost the function
1) to stimulate the T cells inactivation of the B cells in the production of p53, a tumor suppressor gene, or antioncogene that inhibits the cancer cell proliferation and tumor development and
2) to simulate the production of pro-inflammatory cytokines to kill off the DNA alternated damage cells in the acute phase of inflammation.
In other words, if you have a strong immune system, your risk of cancer is substantially lower compared to the general public.
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere. the herbal plant has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.
The Shandong University at Weihai, on the finding a natural compound for the treatment of cancer with no side effects examined a new bakkenolide isolated from Butterbur anti-cancer effects.
The new bakkenolide exerted a potent cytotoxic activity against a number of cultured human cancer cells, including human cervical carcinoma (HeLa), human breast cancer (MCF-7) and murine Lewis lung carcinoma (LLC) cell lines.
According to the National Veterinary Research and Quarantine Service in vitro methanol extract from the leaves in the rat liver epithelial cells. significantly decreased spontaneous beta-galactosidase activity and beta-galactosidase activity induced by a mutagen.
Elevated beta-galactosidase (beta-gal) enzyme activity is an indication of the tumor and metastatic expression.
All doses of the extract (0.08-100 mg/plate) decreased the reversion frequency induced by benzo (alpha)pyrene (BaP) in S. Typhimurium TA 98 of the Salmonella typhimurium.
Additional analysis of the experiment, PJ extract showed greater cytotoxic effects on human stomach, colon, and uterus cancer cells than on other cancer cell types and normal rat liver epithelial cells.
Furthermore, PJ significantly increased the numbers of gap junction proteins associated with tumor suppression in a dose-dependent manner.
Dr. the lead scientist said, "Based on these findings, PJ is suggested to contain antimutagenic and anticarcinogenic compounds".
Taken altogether, herbal Butterbur may be considered a functional remedy for the prevention and combined with the primary medicine for the treatment of cancers.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Bakkenolides from Petasites tatewakianus by Dong XW, Li RJ, Gao X, Row KH.(PubMed)
(2) Antimutagenic and anticarcinogenic effect of methanol extracts of Petasites japonicus Maxim leaves by Kang HG, Jeong SH, Cho JH.(PubMed)
(3) Interactions between the tumor suppressor p53 and immune responses by Menendez D1, Shatz M, Resnick MA. (PubMed)
Whole Food Honey, the Best Remedy for the Prevention and Treatment of Reflux Esophagitis
Scientists may have found a natural alternative for the treatment of reflux esophagitis, some studies found.
Acid Reflux or heartburn is a condition characterized by the going back up of acidic stomach contents to the esophagus. Most cases of acid reflux are happened immediately after eating causing a burning sensation or pain in the lower chest area.
According to the statistics, in the US, approximately, 20% of people with acid reflux will develop gastroesophageal reflux disease (GERD). More than 65% of people who suffer from acid reflux are 40 years old or older. And, 15 to 30 5 of the U.S. population has GERD.
Too much tea, coffee, and alcohol smoking pregnancy, obesity, eating habits such as eating close to bedtime, eating a large meal, eating fatty and fried foods are some of the risk factors that initiate to the early onset of acid reflux, according to the epidemiological studies.
Believe it or not, long-term intake of certain medication such as bronchodilators for asthma, progestin for birth control or to treat abnormal menstrual bleeding, sedatives for insomnia and anxiety, calcium channel blockers for high blood pressure.
Dr. Zeynel Mungan and colleagues in examing the medication risk of GERD wrote, "Gastroesophageal reflux disease (GERD), which is common in many communities, is associated with structural factors, eating habits, and the use of certain drugs".
And, "The use of such drugs can lead to the emergence of GERD and can also exacerbate existing reflux symptoms. These drugs can contribute to GERD by directly causing mucosal damage, by reducing lower esophageal sphincter pressure (LESP), or by affecting esophagogastric motility".
Therefore, if you currently taking some of the aforementioned medication, please make sure that you know all the side effects for preventive measure.
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Scientists on the finding a natural remedy for the treatment of acid reflux investigated the honey effect on reflux oesophagitis (RE).
Injection honey displayed a strong effect on reflux oesophagitis through inhibiting the free radical expression which has been found to be mediators in the generation of RE.
Furthermore, besides inhibiting the over expression of free radicals, honey also promoted the production of antioxidants enzymes in the host, leading to the balanced ratio of free radical and antioxidant in the body.
Moreover, honey injection also reduced the levels of inflammation by inhibiting the nitric oxide and prostaglandin E2 production associated with free radical and inflammation, respectively.
The effects of honey against RE also attributed to the nature of high density, high viscosity, and low surface tension, that make them stay longer in the esophagus as a coating on the mucous membrane.
Additionally, researchers also found that the anti-RE activity of honey was also due to its nonperoxide antibacterial activity.
The findings suggested honey inhibits the onset of progression RE through a number of mechanisms, including proteins associated with the production of pro-inflammatory cytokines and antioxidant enzymes produced by the honey and the host.
Taken altogether, honey may be considered a functional remedy for the prevention and combined with the primary therapy for the treatment of reflux esophagitis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Honey - A nutrient with medicinal property in reflux oesophagitis by Mahantayya V. Math,* Rita M. Khadkikar, and Yashoda R. Kattimani. (PubMed)
(2) Which drugs are risk factors for the development of gastroesophageal reflux disease? by Zeynel Mungan, Binnur Pınarbaşı Şimşek. (University School of Medicine and İstinye University School of Medicine)
Thursday, April 18, 2019
Herbal Bilberry Modulates the Expression of Energy Metabolism, According to Scientists
Bilberry may be the next potential target by the pharmaceutical companies to extract a single ingredient medicine for improvement of energy metabolism, according to studies.
Energy metabolism is a process to generate energy from protein, fat and carbohydrate or fat already stored in the body.
Although carbohydrates and fat are considered the major sources of energy in the diet, protein is necessary for all kinds of biological processes but less in the direct production of energy purposes.
Energy metabolism alterations are found associated with a large number of diseases including mitochondrial diseases, acute coronary syndrome, chronic kidney disease, asthma or even cancer.
And, energy metabolism alternation can also affect all organs and tissues functioning.
Certain factors can increase and decrease the rate of energy metabolism, such as the immune cells require energy to maintain cellular viability and to perform specific immune functions, including
* Body size such as weight and heigh
* Body composition: fat tissue has a lower metabolic activity than muscle tissue.
* Aging: decrease muscle mass decrease energy metabolism.
* Gender women have a slow rate of energy metabolism compared to men.
Dr. Prabhakar, the lead scientist in the investigation of the energy metabolism on obesity, said, "Energy used by the body is described in terms of the metabolic rate underlying passive and active conditions which are further correlated to body weight".
And, "Energy metabolism and the role of carbohydrates, lipids, and protein in foods are areas of emerging research with a therapeutic approach against obesity and related biological disorders". of e
The results strongly suggested that if you are obese, you are at higher risk of diseases associated with a decreased rate of energy metabolism, such as insulin resistance.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding the natural ingredient for the improvement of energy metabolism investigated the bilberry activity in genes expressed in the intestinal mucosa which is responsible for nutrient absorption and waste secretion.
Injection of bilberry improved the intestinal barrier functioning by enhancing the balance of gut microbiota, thus increasing the absorption of the nutrients.
Furthermore, male C57BL/6J mice (n = 52) selected to the study received a control low-fat diet (LFD; 10 kcal% fat) for 6 weeks followed by 24 weeks of either LFD (n = 13) or high-fat diet (HFD; 45 kcal% fat; n = 13) or HFD supplemented with 0.1% w/w of the flavanol compound epicatechin (HFD+E; n = 13) or an anthocyanin-rich bilberry extract (HFD+B; n = 13), researchers found that
* The switch from an LFD to an HFD increases the plasma cholesterol and hepatic lipid content in non-anthocyanin-rich bilberry extract treatment group.
* The polyphenol compounds in the HFD supplemented with 0.1% w/w of the flavanol compound epicatechin could not prevent HFD-induced systemic rise of inflammatory levels compared to the bilberry treatment group.
* The findings strongly supported the use of supplementation of HFD with an anthocyanin-rich bilberry extract for the beneficial effects on the systemic early inflammatory response associated with HFD-induced obesity.
Dr. the leads scientist wrote, "On the tissue level, long-term treatment with bilberry attenuated TNF-α expression in adipose tissue".
In other words, the intake of anthocyanin-rich bilberry extract lowers the level of systemic inflammation in the adipose tissue against the onset of metabolic syndrome-associated chronic pathologies.
Taken altogether, bilberry may be considered a functional remedy to improve the intestinal barrier functioning in energy metabolism by reducing the intestinal inflammation and promoting healthy adipocytes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Changes in intestinal immunity, gut microbiota, and expression of energy metabolism-related genes explain adenoma growth in bilberry and cloudberry-fed ApcMin mice by Päivärinta E1, Niku M2, Maukonen J3, Storvik M4, Heiman-Lindh A5, Saarela M6, Pajari AM7, Mutanen M8. (PubMed)
(2) Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity. by van der Heijden RA1, Morrison MC2, Sheedfar F3, Mulder P4, Schreurs M5, Hommelberg PP6, Hofker MH7, Schalkwijk C8, Kleemann R2, Tietge UJ5, Koonen DP7, Heeringa P. (PubMed)
(3) 6 - Protein, Carbohydrates, and Fats: Energy Metabolism by Prabhakar Singh, Rajesh K.Kesharwani, Raj K.Keservani. (Science Direct)
Energy metabolism is a process to generate energy from protein, fat and carbohydrate or fat already stored in the body.
Although carbohydrates and fat are considered the major sources of energy in the diet, protein is necessary for all kinds of biological processes but less in the direct production of energy purposes.
Energy metabolism alterations are found associated with a large number of diseases including mitochondrial diseases, acute coronary syndrome, chronic kidney disease, asthma or even cancer.
And, energy metabolism alternation can also affect all organs and tissues functioning.
Certain factors can increase and decrease the rate of energy metabolism, such as the immune cells require energy to maintain cellular viability and to perform specific immune functions, including
* Body size such as weight and heigh
* Body composition: fat tissue has a lower metabolic activity than muscle tissue.
* Aging: decrease muscle mass decrease energy metabolism.
* Gender women have a slow rate of energy metabolism compared to men.
Dr. Prabhakar, the lead scientist in the investigation of the energy metabolism on obesity, said, "Energy used by the body is described in terms of the metabolic rate underlying passive and active conditions which are further correlated to body weight".
And, "Energy metabolism and the role of carbohydrates, lipids, and protein in foods are areas of emerging research with a therapeutic approach against obesity and related biological disorders". of e
The results strongly suggested that if you are obese, you are at higher risk of diseases associated with a decreased rate of energy metabolism, such as insulin resistance.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding the natural ingredient for the improvement of energy metabolism investigated the bilberry activity in genes expressed in the intestinal mucosa which is responsible for nutrient absorption and waste secretion.
Injection of bilberry improved the intestinal barrier functioning by enhancing the balance of gut microbiota, thus increasing the absorption of the nutrients.
Furthermore, male C57BL/6J mice (n = 52) selected to the study received a control low-fat diet (LFD; 10 kcal% fat) for 6 weeks followed by 24 weeks of either LFD (n = 13) or high-fat diet (HFD; 45 kcal% fat; n = 13) or HFD supplemented with 0.1% w/w of the flavanol compound epicatechin (HFD+E; n = 13) or an anthocyanin-rich bilberry extract (HFD+B; n = 13), researchers found that
* The switch from an LFD to an HFD increases the plasma cholesterol and hepatic lipid content in non-anthocyanin-rich bilberry extract treatment group.
* The polyphenol compounds in the HFD supplemented with 0.1% w/w of the flavanol compound epicatechin could not prevent HFD-induced systemic rise of inflammatory levels compared to the bilberry treatment group.
* The findings strongly supported the use of supplementation of HFD with an anthocyanin-rich bilberry extract for the beneficial effects on the systemic early inflammatory response associated with HFD-induced obesity.
Dr. the leads scientist wrote, "On the tissue level, long-term treatment with bilberry attenuated TNF-α expression in adipose tissue".
In other words, the intake of anthocyanin-rich bilberry extract lowers the level of systemic inflammation in the adipose tissue against the onset of metabolic syndrome-associated chronic pathologies.
Taken altogether, bilberry may be considered a functional remedy to improve the intestinal barrier functioning in energy metabolism by reducing the intestinal inflammation and promoting healthy adipocytes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Changes in intestinal immunity, gut microbiota, and expression of energy metabolism-related genes explain adenoma growth in bilberry and cloudberry-fed ApcMin mice by Päivärinta E1, Niku M2, Maukonen J3, Storvik M4, Heiman-Lindh A5, Saarela M6, Pajari AM7, Mutanen M8. (PubMed)
(2) Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity. by van der Heijden RA1, Morrison MC2, Sheedfar F3, Mulder P4, Schreurs M5, Hommelberg PP6, Hofker MH7, Schalkwijk C8, Kleemann R2, Tietge UJ5, Koonen DP7, Heeringa P. (PubMed)
(3) 6 - Protein, Carbohydrates, and Fats: Energy Metabolism by Prabhakar Singh, Rajesh K.Kesharwani, Raj K.Keservani. (Science Direct)
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