Saturday, October 24, 2015

Most Common Diseases of Ages of 50 Plus - Musculoskeletal disorders (MSDs) - Osteoarthritis Prevention: The Antioxidants

By Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Osteoarthritis (OA), a form of arthritis, is defined as a condition of
as a result of aging causes of wear and tear on a joint, affecting over 25 million people in the United States in alone.

Prevention
C. The Antioxidants
1. Immune system and functioning (Free radical scavengers)
Free Radicals play an important role in the function of the Immune System. The immune systen produces free radicals to kill foreign microbes, but the production of free radical sometime can be excessive, leading to formation of a large number of free radicals. The domino effects have shown to induce many chronic illness.
a. Vitamin A
vitamin A plays an essential roles in enhancing a broad range of immune processes, including white blood cells activation and proliferation, T-helper-cell differentiation, the production of specific antibody in regulation of the immune response(46a).
b. Vitamin C
Researchers found that vitamin C raised the concentration in the blood of total immunoglobulin(46b) in promotion of the ability of antibodies and phagocytic cells to clear pathogens(46c).
c. Vitamin E
Vitamin E not only increased both cell-dividing and IL-producing capacities of naive T cells but also enhanced the immune functions in association with significant improvement in resistance to influenza infection.
d. Zinc
Zinc, as a antioxidant is essential mineral improved immune system by enhancing the proper function of T cells which belong to a group of white blood cells known as lymphocytes, in fighting against damaging free radicals.

2. Antioxidants and osteoarthritis
a. Vitamin E and fish oil
Diet included fish oil plus vitamin E significantly reduce the levels of inflammation by analyzing the pro and anti-inflammatory cytokines in the blood serum.
b. Glucosamine
Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans, a major component of joint cartilage. Supplemental glucosamine showed to prevent cartilage degeneration and treat arthritis, according to study.
c. DLPA (dl- phenylalanine)
DLPA, a mixture of D-Phenylalanine and L-Phenylalanine, is a nutritional supplement amino acid. showed effectively reduces arthritis pain and joint inflammation in many patients.
d. Glucosamine and Methylsulfonylmethane
In a double-blind, placebo-controlled study with osteoarthritis of the knee were given a combination of glucosamine and MSM, or placebo. After 12 weeks, Combination of MSM and glucosamine may improve arthritis symptoms, according to a double-blind, placebo-controlled study
3. Etc.

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/7864688
(46) http://www.ncbi.nlm.nih.gov/pubmed/19158208
(46a) http://www.ncbi.nlm.nih.gov/pubmed/25269669
(46b)http://www.ncbi.nlm.nih.gov/pubmed/22366311
(46c)http://www.ncbi.nlm.nih.gov/pubmed/18147027

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