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Wednesday, September 30, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM Herbal treatments of Dementia Caused by Blood Stasis

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.

C. In traditional Chinese Medicine Perspective(*)
Based on Chinese ancient medical records. causes of dementia are the results of (*)


 C.4.1. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood Stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting  or death of neurons, cognitive impairments(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144), chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).

Herbal medicine for treatment of Blood stasis
1. Wolfberry (Gou qi)
Gou Qi, the sweet and neutral herb is also known as wolfberry, used in TCM as anti cancers(1148)(1149), antioxidative(1150)(1151) and anti aging(1156)(1157) agent and to treat back, leg, and stomach pain(1152), hypopigmentation(1154), improve vision(1153)(1154), diabetes(1155), premature aging(1156), enhance immune system(1157), lower blood lipids(1158), elevate level of testosterone(1159), simulate estrogen and anti estrogen effect through different estrogen receptor mechanisms(1160) etc., as it nourishes and tonifies Liver and Kidneys, moistens the Lungs, etc., by enhancing the functions of liver, lung and kidney channels(1161). 

Phytochemicals
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.

1.1.  In Alzheimer's disease(AD)
 Elevated plasma homocysteine (Hcy) levels have shown to be associated to increased the risk of Alzheime's disease (AD), epidemiologically and clinically. Polysaccharides, phytochemicals derived from wolfberry (LBA) not only inhibited Abeta accumulation but also reduced risk of other factors induced AD(1162). According to the University of Hong Kong, the chemical olysaccharides, also ameliorated glutamate excitotoxicity involved in many neurodegenerative diseases including Alzheimer's disease (AD)(1163). The herbal alkaline extract was found to exhibit neuroprotection, through inhibiting Abeta-peptides induced apoptosis and neuronal cell death(1164).

1.2. In neuroprotective effects
Lycium barbarum polysaccharide (LBP), on focal cerebral ischemic injury in mice model, inhibited neuronal morphological damage and attenuated the neuronal apoptosis through mitochondrial apoptosis pathway(1165). In ischemia-reperfusion-induced damage, chemical Lycium barbarum polysaccharides (LBP), reduced apoptosis and a decrease number of viable cells in the ganglion cell layer (GCL) and inner nuclear layer (INL), through its  antioxidant activity(1166), In PC12 cell, Lycium barbarum extracts inhibited neurotoxin  induced Parkinson's disease-like syndrome, through increased intracellular Ca (2+) level and significantly cell viability and cellular ATP levels(1167).

1.3. In cognitive impairment
In prenatal stress-induced cognitive impairment of offspring rats, Lycium barbarum showed to inhibit brain oxidative mitochondrial damage and cognitive dysfunction, through its scavenged hydroxyl and superoxide radicals(1168). Kyung-Ok-Ko (KOK), a traditional herbal prescription, containing Lycium, showed to enhance neuroprotective effects in attenuation of memory impairment, probably through its anti-inflammatory activities(1169).

1.4. In learning and memory
Lycium barbarum polysaccharides, scopolamine (SCO-induced cognitive and memory deficits in rats model, ameliorated and suppressed oxidative stress in hippocampus, and neurons apoptosis(1170). On transgenic mouse model of Alzheimer's disease, Gou qi extracts at 10 mg/kg improved the performance of  the learning and the memory retrieval phases of tested models, through reduced levels of Aβ(1-42) in hippocampal tissue(1171). According to Kyung Hee University, Lycium chinense fruit, in trimethyltin (TMT)-induced neuronal and cognitive impairment rats model, improved learning and memory deficit in impaired learning and memory scores(1172).
2. Polygonum multiflorum (he shou wu)
He Shu Wu or Ye Jiao Teng or Shu Wu is also known as Fleece flower root or  Fo-ti.
a. The prepared herb is astringent with some sweetness, mildly warm
b. The raw herb is bitter, sweet and neutral
used in TCM to treatment of hyperlipemia(1173), neurasthenia(1174), split personality(1174), promoted hair grown(1175) and prevent hair loss(1176) due to aging, skin rash due to inflammation(1177), etc., as the herb tonifies and benefits  the essence and blood, expels toxins, moistens the intestines, etc. by enhancing the (The prepared herb) liver and kidney channels and (The raw herb) liver, heart and large intestine channels(1178).

Phytochemicals
1. Polygoacetophenoside
2. Chrysophanol
3. Emodin
4. Rhein
5. Emodin-6
6. Physcion
7. Chrysophanic acid
8. Anthrone
9. beta-sitosterol
10. 2,3,5,4′-tetrahydroxystibene-2O-b-D-glucoside
11. Quercetin-3-O-galactoside
12. Querctin-3-O-arabinoside
13. Lecithin
14. Etc.

1. In  Alzheimer's disease
Polygonum multiflorum extract, showed to significantly improved AD patients with total effective rate of 93.33% in clinical trial, according to Third Xiangya Hospital(1179). In rat model, induced Alzheimer's disease by injecting Abeta 1-40, exhibited improvement of learning and memory ability, through expression of the fluidity of mitochondria membrane and the activity of mitochondrial COX(1180) and ameliorated hippocampal synapses count and synaptophysin expression(1181). In cognitive deficits induced by Abeta25-35, Polygonum multiflorum Thunb water extract, also significantly ameliorated the cognitive deficits, probably due to its antioxidant properties(1182).

2. In Parkinson disease
Strong evidences suggested that agricultural chemicals and environment toxins, such as dithiocarbamate fungicides such as manganese ethylenebisdithiocarbamate [maneb (MB)], impact dopamine systems has shown to associate to the development of Parkinson's disease,(1184)(1185)
In nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice model, ethanol-soluble PME (PME-I) water extracts from Polygonum multiflorum, showed to improve locomotor activity, motor incoordination, and declines of dopamine level, probably through phytochemicals, in the ethanol-soluble fraction of PME (PME-I)(1183).

3. In neuroprotective effects
In focal cerebral ischemia in mice, hexane extracts of Polygonum multiflorum, exhibited its neuroprotective effects though significantly decreased infarct size and improved neurological and motor function, (1186) and decreased glutamate-induced neurotoxicity in a concentration-dependent manner and prevention of apoptosis of cortical neurons(1187), in HT22 hippocampal cells(1188), probably through it antioxidant activity. According to Xuanwu Hospital of Capital Medical University, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extracted from Polygonum multiflorum, also improved mitochondrial function, decreased oxidative stress and inhibited apoptosis against induced cytotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells(1188).

4. In learning and memory
 Dietary supplementation with either ethanol or water extracts of Polygonum multiflorum has shown to reduce brain pathological changes and promote learning and memory ability(1191)(1192). In male Sprague-Dawley rats, injected with beta amyloid (Aβ), tetrahydroxystilbene glucoside, an active chemical constituent of extract from  Polygonum multiflorum, significantly improved the learning and memory, through by protecting synaptic structure and function(1189) and learning and/or memory ability of aged rats by increased Beta-secretase 1 (BACE1), a beta-site amyloid precursor protein cleaving enzyme 1 and  decrease ADAM10 (metallopeptidase domain 10), a protein associated to the development of Alzheimer's disease(1190).

For other Healthy Kid loved recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
 
Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia caused by Blood Stasis - Treatments  in Traditional Chinese Herbal Medicine by Kyle J. Norton.


References
(*) http://www.hindawi.com/journals/ecam/2012/692621/ 
(842) http://www.ncbi.nlm.nih.gov/pubmed/25313575
(843) http://www.ncbi.nlm.nih.gov/pubmed/24224039
(844) http://www.ncbi.nlm.nih.gov/pubmed/23391905
(1142) http://www.ncbi.nlm.nih.gov/pubmed/24288569 
(1143) http://www.classicalchinesemedicine.org/2010/03/blood-blood-stasis-and-blood-path-disorders/
(1144) http://www.goodreads.com/book/show/2250018.Aging_Blood_Stasis 
(1145) http://www.tcvm.com/NewsArticles/TabId/245/ArtMID/1382/ArticleID/97/A-Look-at-Blood-Stasis.aspx 
(1147) http://www.ncbi.nlm.nih.gov/pubmed/23893237
(1148) http://www.ncbi.nlm.nih.gov/pubmed/23817098
(1149) http://www.ncbi.nlm.nih.gov/pubmed/12561612
(1150) http://www.ncbi.nlm.nih.gov/pubmed/24972978
(1151) http://www.ncbi.nlm.nih.gov/pubmed/25603493
(1152) http://www.ncbi.nlm.nih.gov/pubmed/22483979
(1153) http://www.ncbi.nlm.nih.gov/pubmed/22567031
(1154) http://www.ncbi.nlm.nih.gov/pubmed/21169874
(1155) http://www.ncbi.nlm.nih.gov/pubmed/25381995
(1156) http://www.ncbi.nlm.nih.gov/pubmed/?term=wolfberry+aging
(1157) http://www.ncbi.nlm.nih.gov/pubmed/25552899
(1158) http://www.ncbi.nlm.nih.gov/pubmed/20673056
(1159) http://www.ncbi.nlm.nih.gov/pubmed/21077258
(1160) http://www.ncbi.nlm.nih.gov/pubmed/19373615
(1161) http://alternativehealing.org/qi_zi.htm
(1162) http://www.ncbi.nlm.nih.gov/pubmed/20157238
(1163) http://www.ncbi.nlm.nih.gov/pubmed/19499323
(1164) http://www.ncbi.nlm.nih.gov/pubmed/17568570
(1165) http://www.ncbi.nlm.nih.gov/pubmed/24595452
(1166) http://www.ncbi.nlm.nih.gov/pubmed/24400114
(1167) http://www.ncbi.nlm.nih.gov/pubmed/24228605
(1168) http://www.ncbi.nlm.nih.gov/pubmed/20131093
(1169) http://www.ncbi.nlm.nih.gov/pubmed/22020275
(1170) http://www.ncbi.nlm.nih.gov/pubmed/24505383
(1171) http://www.ncbi.nlm.nih.gov/pubmed/23737913
(1172) http://www.ncbi.nlm.nih.gov/pubmed/22110372
(1173) http://www.ncbi.nlm.nih.gov/pubmed/17455469
(1174) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+cognitive+degeneration
(1175) http://www.ncbi.nlm.nih.gov/pubmed/25612775
(1176) http://www.ncbi.nlm.nih.gov/pubmed/22803359
(1177) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+skin+rash
(1178) http://alternativehealing.org/he_shou_wu.htm
(1179) http://www.ncbi.nlm.nih.gov/pubmed/20622335
(1180) http://www.ncbi.nlm.nih.gov/pubmed/19060365
(1181) http://www.ncbi.nlm.nih.gov/pubmed/17935895
(1182) http://www.ncbi.nlm.nih.gov/pubmed/16219438
(1183) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+Parkinson+disease
(1184) http://www.ncbi.nlm.nih.gov/pubmed/11124998
(1185) http://www.ncbi.nlm.nih.gov/pubmed/19729209
(1186) http://www.ncbi.nlm.nih.gov/pubmed/24534954
(1187) http://www.ncbi.nlm.nih.gov/pubmed/23164763
(1188) http://www.ncbi.nlm.nih.gov/pubmed/21497157
(1189) http://www.ncbi.nlm.nih.gov/pubmed/23181273
(1190) http://www.ncbi.nlm.nih.gov/pubmed/22032649
(1191) http://www.ncbi.nlm.nih.gov/pubmed/12775116
(1192) http://www.ncbi.nlm.nih.gov/pubmed/12856856

Super Nachos

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn

Keep these simple ingredients around for a quick & easy snack the whole family will enjoy
2 (10-inch) flour tortillas
3/4 c. salsa
4.5-oz. can green chiles, drained and diced
1/2 c. sliced black olives
1 c. shredded Monterey Jack cheese
Place tortilla on an ungreased baking sheet: spread salsa over tortilla.prinkle chiles and olives over salsa; top with cheese.
bake at 425 degrees for 10 minutes or until tortillas are crisp and cheese is melted. Use a pizza cutter to slice each into 8 wedges.
Make 8 appetizer servings

Mary Murray
Gooseberry Patch

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Tuesday, September 29, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Shui Fei Zi (Milk thistle) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)

Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5.  According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
 C.5.1. Dementia due to toxins accumulation
Toxins accumulation in  internal organs disturbed the balance of immunity(1213)(1214) may cause  impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination 
1.  Shui Fei Zi or Milk thistle (Silybum marianum)
Shui fei zi, the bitter and cold herb, is also known as milk thistle, native to Western Europe and northern Africa, used in traditional Chinese medicine to improve liver function(1193)(1194)(1210), promote the flow of breast milk(1207), bile secretion(1200), anti depression(1201) and anti tumors(1196)(1197)(1198), inhibit allergic effects(1195)(1199), treat hepatitis C(1202)(1203), cirrhosis(1205) and liver fibrosis(1206), by enhancing function of liver and gallbladder channels(1204)

Phytochemicals
 1. Flavonoid 
2. Fumaric acid
3. Silymarin
4. Isosilybin, 
5. Dehydrosilybin, 
6. Silydianin
7. Silychristin
8. Cinnamic acid
9. Myristic acid
10. Palmitelaidic acid
10. Arachidic acid
11. Etc.  

Shui Fei Zi or Milk thistle used in the treatment and prevention of dementia(1218) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals Silymarin and Silibinin in ameliorated amyloid pathology(1216) and oxidative stress(1216)(1217) through attenuated levels of lipid peroxidation (malondialdehyde) and antioxidant (glutathione) in the hippocampus(1217).

1.1. In Alzheimer's disease
Alzheimer disease (AD). a neurodegenerative disorders is the most prevalent diseases  in the United States, in aging population(1219). Silymarin, a phytochemical found abundantly in milk thistle, in age related disorders like neurodegenerative diseases improved  locomotion rate, higher response to stimuli and tolerance to stress, in C.elegans Alzheimer's Model, through delayed paralysis via enhanced resistance to oxidative stress(1220). In rat induced Alzheimer's disease model, the phytochemical also inhibited amyloid formation(1222) and suppressed amyloid protein precursor (APP) expression(1222)and reduced neurotoxicity in PC12 cells(1222) in improvement memory(1223) and learning function(1221).

1.2. In Parkinson disease
In a mouse model of Parkinson's disease, causes of mitochondrial dysfunction and selective cells death of dopaminergic neurons, silibinin, derivative of silymarin, protected mitochondria through attenuated motor deficit and dopaminergic neuronal loss(1224) and anti oxidative and anti inflammatory pathways(1225).


1.3. In neuroprotective effects  
In focal cerebral ischemia, silymarin (SM), a mixture of flavonolignans extracted from the milk thistle exerted it neuroprotective effects, in upregulating the antioxidant status and lowering the apoptotic response in slowing down the progression of neurodegeneration(1226) and preventing inflammation-related neurodegenerative disease(1227)  and ROS causs of oxidative damage to macromolecules in the brain(1230).


1.4. In cognitive impairment
In cognitive deficit mice model, silibinin exhibited its anti cognitive impairment effects through amelioration of decreases in dopamine and serotonin levels in the prefrontal cortex and hippocampus, (1228). In amyloid beta peptide-induced memory impairment, the chemicals also improve cognitive memory deficits through attenuated the Abeta(25-35)- accumulation of malondialdehyde and depletion of glutathione in the hippocampus(1229).

Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia - Treatments in Traditional Chinese Herbal Medicine by Kyle J. Norton. 

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(*) http://www.hindawi.com/journals/ecam/2012/692621/  
(1193) http://www.ncbi.nlm.nih.gov/pubmed/9468229
(1194) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(1195) http://www.ncbi.nlm.nih.gov/pubmed/23121838
(1196) http://www.ncbi.nlm.nih.gov/pubmed/23879966
(1197) http://www.ncbi.nlm.nih.gov/pubmed/24574320
(1198) http://www.ncbi.nlm.nih.gov/pubmed/25242120
(1199) http://www.ncbi.nlm.nih.gov/pubmed/23701595
(1200) http://www.ncbi.nlm.nih.gov/pubmed/17692492
(1201) http://www.ncbi.nlm.nih.gov/pubmed/25431050
(1202) http://www.ncbi.nlm.nih.gov/pubmed/25247194
(1203) http://www.ncbi.nlm.nih.gov/pubmed/22797645
(1204)  http://alternativehealing.org/shui_fei_ji.htm
(1205) http://www.ncbi.nlm.nih.gov/pubmed/15277093
(1206) http://www.ncbi.nlm.nih.gov/pubmed/22087179
(1207) http://www.ncbi.nlm.nih.gov/pubmed/23468043 
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864 
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069 
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658 
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367 
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080 
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982 
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094 
(1216) http://www.ncbi.nlm.nih.gov/pubmed/21185897 
(1217) http://www.ncbi.nlm.nih.gov/pubmed/19552690 
(1218) http://www.ncbi.nlm.nih.gov/pubmed/21071836 
(1219) http://www.ncbi.nlm.nih.gov/pubmed/25696782
(1220) http://www.ncbi.nlm.nih.gov/pubmed/25613505
(1221) http://www.ncbi.nlm.nih.gov/pubmed/24460990
(1222) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1223) http://www.ncbi.nlm.nih.gov/pubmed/19638571
(1224) http://www.ncbi.nlm.nih.gov/pubmed/25677261
(1225) http://www.ncbi.nlm.nih.gov/pubmed/24660866
(1226) http://www.ncbi.nlm.nih.gov/pubmed/21840019
(1227) http://www.ncbi.nlm.nih.gov/pubmed/20833521
(1228) http://www.ncbi.nlm.nih.gov/pubmed/19857526
(1229) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1230) http://www.ncbi.nlm.nih.gov/pubmed/19647779

Hot Chili Cheese

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn


Be sure to know this hearty dip on your menu the next time family & friends are over to watch the big game..... it will be a hit.
1 lb. mild or spicy ground pork sausage, browned and drained
2 (103/4-oz. cans nacho cheese soup
15-oz. can chili with beans
141/2 oz. can tomatoes with chiles
16-oz. pkg. pasteurized process cheese spread, cubed
Combine all ingredients except cheese in a large saucepan over medium heat; cook until bubbly. Add cheese. Reduced heat; cook and stir until cheese is completely melted.
Make 6 to 7 cups.

David Wink
Gooseberry Patch

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Monday, September 28, 2015

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Xiu Hui Xiang (Fennel) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)

Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5.  According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
 C.5.1. Dementia due to toxins accumulation
Toxins accumulation in  internal organs disturbed the balance of immunity(1213)(1214) may cause  impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with gradual depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination
2. Xiu Hui Xiang (Fennel)
Xiu Hui Xiang, the acrid and warm herb, is also known as fennel, native to Mediterranean, used in traditional Chinese medicine  as anti microbal(1232)(1233), antioxidant(1234)(1235) and emmenagogue(1236) and estrogenic(1244) and androgenic(1245) agents and to prevent bone loss in postmenopausal osteoporosis(1237)(1238), treat hepatic fibrosis(1239), gastro intestine disorder(1240)(1241), decrease hair thickness(1243) and increase flow of breast milk(1242) by enhancing function of liver, kidney, spleen, stomach channels(1231).



Phytoshemicals  
1. Linoleic acid         
2. Palmitic acid  
3. Arachidic acid  
4. Behenic acid      
5. Quercetin  
6. Phytosteryl b-fructofuranoside  
7. 7-hydroxycoumarin 
8. 6,7-dihydroxycoumarin  
9. Oleanolic acid     
10. Sitosterol  
11. Fenchone 
12. α-pinene  
13. Limonene  
14. β-Pinene  
15. β-Myrcene  
16. α-Phellandrene  
17. P-Cymol  
18. Etc. 


Xiu Hui Xiang (Fennel) used in the treatment of symptoms of neurodegenerative disorder, including age-related mental problems of Alzheimer's disease(1246)) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals in acetylcholinesterase inhibition(1246) and anti inflammation(1247) through suppression of the nuclear factor-kappaB activation pathway(1247) involved stress, cell signaling, free radicals, oxidized LDL,activities(1248)(1249)(1250)(1251).

1. In anxiolytic activity
Anxiety is a condition of neurodisorder of unpleasant state of inner turmoil with fear of the presence and future, according to Diagnostic and Statistical Manual of Mental Disorders American Psychiatric Association, effecting patients with dementia, included familial Alzheimer's disease(1252) and other neuropsychiatric disorders(1254). Fennel, a medical herb used in many cultures, have shown effectively in treating anxiety, epidemiologically. In adult Swiss albino male mice, oral administration 100 and 200 mg/kg doses of fennel essential oil significantly increased percent number of entries and time spent in open arms in elevated plus maze (EPM) test(1255).


2. In learning and memory
Fennels, the most widely used herbal plant in the world(1256) used in traditional Iranian medicine and modern phytotherapy for memory enhancing(1257).  In Alzheimer's disease, induced a decline of cognitive abilities in mice model, fennel extract successfully ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging- induced memory deficits in 8 days in dose-depend manner, through increased step-down latency and acetylcholinesterase inhibition(1258).

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(*) http://www.hindawi.com/journals/ecam/2012/692621/  
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864 
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069 
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658 
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367 
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080 
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982 
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094 

(1231) http://alternativehealing.org/xiao_hui_xiang.htm

(1232) http://www.ncbi.nlm.nih.gov/pubmed/25384804
(1233) http://www.ncbi.nlm.nih.gov/pubmed/21462837
(1234) http://www.ncbi.nlm.nih.gov/pubmed/21812646
(1235) http://www.ncbi.nlm.nih.gov/pubmed/25143939
(1236) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+emmenagogue
(1237) http://www.ncbi.nlm.nih.gov/pubmed/22447109
(1238) http://www.ncbi.nlm.nih.gov/pubmed/25050267
(1239) http://www.ncbi.nlm.nih.gov/pubmed/22475144
(1240) http://www.ncbi.nlm.nih.gov/pubmed/22433535
(1241) http://www.ncbi.nlm.nih.gov/pubmed/20433751
(1242) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1243) http://www.ncbi.nlm.nih.gov/pubmed/24490010
(1244) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1245) http://www.ncbi.nlm.nih.gov/pubmed/13678227
(1246) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+dementia
(1247) http://www.ncbi.nlm.nih.gov/pubmed/15659827
(1248) http://www.nature.com/onc/journal/v25/n51/full/1209954a.html
(1249) http://link.springer.com/article/10.1385%2FCT%3A6%3A2%3A111
(1250) http://www.ncbi.nlm.nih.gov/pubmed/10602459
(1251) http://www.nature.com/nrm/journal/v8/n1/full/nrm2083.html
(1252) http://www.ncbi.nlm.nih.gov/pubmed/25688083
(1253) http://www.ncbi.nlm.nih.gov/pubmed/25687925
(1254) http://www.ncbi.nlm.nih.gov/pubmed/25653291
(1255) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+and+anxiety
(1256) http://www.ncbi.nlm.nih.gov/pubmed/25162032
(1257) http://www.ncbi.nlm.nih.gov/pubmed/23275017

Macadamia Nut Dip


Recipe contributed by Quick and easy family favorites by Vickie and JoAnn


Prepare horseradish lend a pungent bite to this otherwise mild and creamy appetizer

8-oz. pkg. cream cheese, softened
1/2 cup of sour cream
1 c. macadamia nuts, chopped
2 T. prepared horseradish
2 green inion, minced
1/8 t. garlic salt
assorted crackers
Mix together all ingredients except crackers; chill. Serve with crackers. Make 6 to 10 servings.

Judy Borecky
Escondido, CA


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Saturday, September 26, 2015

Fruit Salsa with Cinnamon

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn


Kiwis, apple, raspberries, and strawberry make up this colorful salsa. It 'll be a treat that guests will not want to miss.....especially when served with homemade cinnamon chips.
2 kiwis, peeld and diced
2 Golden delicious apples. cored, peeled and diced
1/2 Lb. raspberries
16 Oz. pkg. strawberry, bulled and diced
1 c. plus 2 T. sugar and divided
1 T. brown sugar, packed
3 T. strawberry preserses
1 to 2 T. cinnamon
10 (10-inch) flour tortillas, sliced into wedges
butter flavored non-stick vegetable spray

Combined all fruits into a large bowl, mix in 2 tsp. sugar, brown sugar and strawberry preserves. Cover and chill for 15 minutes.
Mix together remaining 1 cup of sugar and cinnamon. Arrange tortilla wedges in a single layer on an ungreased baking sheet; coat chips with butter flavored vegetable spray. Sprinkle with desired amount of cinnamon-sugar.
Bake at 350 degrees for 8 to 10 minutes. Repeat with remaining tortilla wedges, cool 15 minutes. Serve chips with chilled fruit mixture.
Makes 10 to 15 servings

Ashley Connelly, Louisa, VA

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Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM Herbal Polygonum multiflorum (He shou wu) treatments of Dementia Caused by Blood Stasis

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

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By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)

Based on Chinese ancient medical records. causes of dementia are the results of (*)
 C.4.1. Dementia due to Blood Stasis
According to Chinese medical literaure over 3000 years of history, blood Stasis may be caused by spleen qi deficiency, but in most cases, it is due to heart qi deficiency cause of inability in transport nutrients to the body organs and cells, including the brain. Prolong period of malnutrition of brain cells may induce abnormal function of brain's cells in information transmitting  or death of neurons, causing cognitive impairment(844), including learning and memory deficits(842) and changes in brain tissues and behavior patterns(843)(842). Blood statsis induced by cold(1142), emotional disorder(1143), aging(1144), chronic illnesses and consumptive disease(1145), can overload the heart capacity, contributing to long-term hypertension(1146) due to decreased or impeded blood flow(1147) causes of hypo-perfusion in cerebral blood flow or acute focal stroke in memory-related cerebral parenchyma induced progression of cognitive decline(*).

2. Polygonum multiflorum (he shou wu)
He Shu Wu or Ye Jiao Teng or Shu Wu is also known as Fleece flower root or  Fo-ti.
a. The prepared herb is astringent with some sweetness, mildly warm
b. The raw herb is bitter, sweet and neutral
used in TCM to treatment of hyperlipemia(1173), neurasthenia(1174), split personality(1174), promoted hair grown(1175) and prevent hair loss(1176) due to aging, skin rash due to inflammation(1177), etc., as the herb tonifies and benefits  the essence and blood, expels toxins, moistens the intestines, etc. by enhancing the (The prepared herb) liver and kidney channels and (The raw herb) liver, heart and large intestine channels(1178).

Phytochemicals
1. Polygoacetophenoside

2. Chrysophanol
3. Emodin
4. Rhein
5. Emodin-6
6. Physcion
7. Chrysophanic acid
8. Anthrone
9. beta-sitosterol
10. 2,3,5,4′-tetrahydroxystibene-2O-b-D-glucoside
11. Quercetin-3-O-galactoside
12. Querctin-3-O-arabinoside
13. Lecithin
14. Etc.

1. In  Alzheimer's disease
Polygonum multiflorum extract, significantly improved AD patients with total effective rate of 93.33% in clinical trial, according to Third Xiangya Hospital(1179). In rat model, induced Alzheimer's disease by injecting Abeta 1-40, exhibited improvement of learning and memory ability, through expression of the fluidity of mitochondria membrane and the activity of mitochondrial COX(1180) and ameliorated hippocampal synapses count and synaptophysin expression(1181). In cognitive deficits induced by Abeta25-35, Polygonum multiflorum water extract, also significantly ameliorated the cognitive deficits, probably due to its antioxidant properties(1182).

2. In Parkinson disease
Strong evidences suggested that agricultural chemicals and environment toxins, such as dithiocarbamate fungicides, impacted dopamine systems has shown to associate to the development of Parkinson's disease,(1184)(1185). In nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice model, ethanol-soluble PME (PME-I) water extracts from Polygonum multiflorum, improved locomotor activity, motor incoordination, and declines of dopamine level, probably through phytochemicals, in the ethanol-soluble fraction(1183).

3. In neuroprotective effects
In focal cerebral ischemia mice, hexane extracts of Polygonum multiflorum, exhibited its neuroprotective effects though significantly decreased infarct size and improved neurological and motor function, (1186) and attenuated glutamate-induced neurotoxicity in a concentration-dependent manner and prevented apoptosis of cortical neurons(1187), in HT22 hippocampal cells(1188), probably through it antioxidant activity. According to Xuanwu Hospital of Capital Medical University, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) extract from Polygonum multiflorum, also improved mitochondrial function, decreased oxidative stress and inhibited apoptosis against induced cytotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells(1188).

4. In learning and memory
 Dietary supplementation with either ethanol or water extracts of Polygonum multiflorum has shown to reduce brain pathological changes and promote learning and memory ability(1191)(1192). In male Sprague-Dawley rats, injected with beta amyloid (Aβ), tetrahydroxystilbene glucoside, an active chemical constituent of extract from  Polygonum multiflorum, significantly improved the learning and memory, through protecting synaptic structure and function(1189) and learning and/or memory ability of aged rats by increased Beta-secretase 1 (BACE1), a beta-site amyloid precursor protein cleaving enzyme 1 and  decreased ADAM10 (metallopeptidase domain 10), a protein associated to the development of Alzheimer's disease(1190).

For other Healthy Kid loved recipes http://kylejnorton.blogspot.ca/p/recipes.html
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
 
Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia caused by Blood Stasis - Treatments  in Traditional Chinese Herbal Medicine by Kyle J. Norton

References
(*) http://www.hindawi.com/journals/ecam/2012/692621/ 
(842) http://www.ncbi.nlm.nih.gov/pubmed/25313575
(843) http://www.ncbi.nlm.nih.gov/pubmed/24224039
(844) http://www.ncbi.nlm.nih.gov/pubmed/23391905
(1142) http://www.ncbi.nlm.nih.gov/pubmed/24288569 
(1143) http://www.classicalchinesemedicine.org/2010/03/blood-blood-stasis-and-blood-path-disorders/
(1144) http://www.goodreads.com/book/show/2250018.Aging_Blood_Stasis 
(1145) http://www.tcvm.com/NewsArticles/TabId/245/ArtMID/1382/ArticleID/97/A-Look-at-Blood-Stasis.aspx
(1147) http://www.ncbi.nlm.nih.gov/pubmed/23893237
(1173) http://www.ncbi.nlm.nih.gov/pubmed/17455469
(1174) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+cognitive+degeneration
(1175) http://www.ncbi.nlm.nih.gov/pubmed/25612775
(1176) http://www.ncbi.nlm.nih.gov/pubmed/22803359
(1177) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+skin+rash
(1178) http://alternativehealing.org/he_shou_wu.htm
(1179) http://www.ncbi.nlm.nih.gov/pubmed/20622335
(1180) http://www.ncbi.nlm.nih.gov/pubmed/19060365
(1181) http://www.ncbi.nlm.nih.gov/pubmed/17935895
(1182) http://www.ncbi.nlm.nih.gov/pubmed/16219438
(1183) http://www.ncbi.nlm.nih.gov/pubmed/?term=Polygonum+multiflorum+Parkinson+disease
(1184) http://www.ncbi.nlm.nih.gov/pubmed/11124998
(1185) http://www.ncbi.nlm.nih.gov/pubmed/19729209
(1186) http://www.ncbi.nlm.nih.gov/pubmed/24534954
(1187) http://www.ncbi.nlm.nih.gov/pubmed/23164763
(1188) http://www.ncbi.nlm.nih.gov/pubmed/21497157
(1189) http://www.ncbi.nlm.nih.gov/pubmed/23181273
(1190) http://www.ncbi.nlm.nih.gov/pubmed/22032649
(1191) http://www.ncbi.nlm.nih.gov/pubmed/12775116
(1192) http://www.ncbi.nlm.nih.gov/pubmed/12856856

Friday, September 25, 2015

Cream Cheese Apple Dip



Recipe contributed by Quick and easy family favorites by Vickie and JoAnn




Offer marshmallows and pretzels along side apple slices to go with this creamy dip.
8-Oz. pkg, cream cheese, soften
1/4 c. sugar
3/4 c. brown sugar, packed
1. t vanilla
1/2 toffee baking bits
apple slices
Blend together cream cheese and sugar; mix in vanilla. Stir in toffee bit. Serve at room temperature with apple slice/ Store in refrigerator. Make about 2 cups.

By Staci Meyers, Cocoa, FL

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Celebrity Patti Stanger Will Coach You To Get Him/Her
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Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Da Suan (Garlic) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)

Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5.  According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
 C.5.1. Dementia due to toxins accumulation
Toxins accumulation in  internal organs disturbed the balance of immunity(1213)(1214) may cause  impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with gradual depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination
3. Da Suan(Garlic) used in the treatment of symptoms of dementia(1283)(1284)(1285), including Alzheimer's pathophysiology(1288)(1289) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals aged garlic extract and S-allyl-L-cysteine and extracts(1284) in oxidative stress inhibition(1284) and anti progression involved association of degeneration and neuro inflammatory activity(1286) through neuro protection against amyloid-beta peptide-induced apoptosis(1285) and toxicity(1287).

3.1. In Alzheimer's disease
Strong evidences suggested that deposited amyloid-beta(Abeta) has shown to associated to the progression in Alzheimer's disease (AD)(1290)(1291)(1292), In  mouse model induced by neurotoxic amyloid beta protein (Aβ), ethyl acetate fractions of garlic extract exhibited high levels of radical scavenging activity involved cognitive impairment against Aβ-induced neuronal deficit and  Aβ-induced learning and memory deficits in vivo(1293). According to Indiana University School of Medicine, the extracts also attenuated synaptic degeneration and neuroinflammatory pathways associated with AD, through major phytochemical S-allyl-L-cysteine (SAC) (1294), including oxidative insults to neurons(1295). In Alzheimer's transgenic model Tg2576, dietary aged garlic extract (AGE) (2%) showed to exhibited anti-amyloidogenic, anti-inflammatory and anti-tangle effects also through its phytochemicals S-allyl-cysteine (SAC) (20 mg/kg) and di-allyl-disulfide (DADS)(1296) without without interfering with its antibiotic activity in ameliorate gentamicin (GM)effectiveness(1297).

3.2. In Parkinson disease
 Olfactory dysfunction(1298)(1299) in non-motor functioning and hyposmia(1300)(1301)/anosmia(1302)(1303) are common manifestation in some neurodegenerative disorders caused by oxidative stress (OS) and inflammatory insults(1305), including Parkinson disease. Dietary supplement S-methyl-L-cysteine,  a substrate in the catalytic antioxidant system mediated by MSRA showed to protect cells from oxidative damage through its antioxidative effect(1304) when used conjunction with methionine sulfoxide reductase A in Parkinson's-like symptoms(1304).

3.3. In Cognitive impairment
In early cognitive deficits caused by gradually of accumulation of beta-amyloid peptide (Abeta) oligomers of Abeta42 species, aged garlic extract, in mice model, prevented progressive behavioral impairment, slowed  plaque development, through protection against deterioration of hippocampal based memory(1306), In Alzheimer's disease induced mice model, S-allyl cysteine, a component of aged garlic extract, ameliorated cognitive deficits and oxidative damage in the hippocampus of intracerebroventricular streptozotocin (ICV-STZ)(1308). According to Gyeongsang National University, the effectiveness of aged garlic extracts, in neurodegenerative disorders, notably Alzheimer's disease(AD), may be due to its antioxidant activities in improvement of cognitive impairment against Aβ-induced neuronal deficit(1307).

3.4. In learning and memory
Acute and chronic oral administration of aged garlic extract, in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze, improved learning and memory probably due to cortical acetylcholinesterase (AchE) and reduced glutathione (GSH) levels activities and anti-oxidant property(1309). In oxidative damage and spatial learning and memory deficits induced mice model, S-allylcysteine exerted its protective effect against reactive oxygen species. Abeta(25-35)-induced hippocampal toxicity and learning deficits, through its free radical  scavenging and ameliorated lipid peroxidation activities(1310).

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
 (1258) http://alternativehealing.org/garlic.htm
(1259) http://www.ncbi.nlm.nih.gov/pubmed/10594976
(1260) http://www.ncbi.nlm.nih.gov/pubmed/11759674
(1261) http://www.ncbi.nlm.nih.gov/pubmed/24066081
(1262) http://www.ncbi.nlm.nih.gov/pubmed/9131291
(1263) http://www.ncbi.nlm.nih.gov/pubmed/25078449
(1264) http://www.ncbi.nlm.nih.gov/pubmed/24859825
(1265) http://www.ncbi.nlm.nih.gov/pubmed/24309133
(1266) http://www.ncbi.nlm.nih.gov/pubmed/23543654
(1267) http://www.ncbi.nlm.nih.gov/pubmed/23923607
(1268) http://www.ncbi.nlm.nih.gov/pubmed/17918162
(1269) http://www.ncbi.nlm.nih.gov/pubmed/10192909
(1270) http://www.ncbi.nlm.nih.gov/pubmed/25141365
(1271) http://www.ncbi.nlm.nih.gov/pubmed/16484559
(1272) http://www.ncbi.nlm.nih.gov/pubmed/24067391
(1273) http://www.ncbi.nlm.nih.gov/pubmed/24172194
(1274) http://www.ncbi.nlm.nih.gov/pubmed/24199984
(1285) http://www.ncbi.nlm.nih.gov/pubmed/25671065
(1276) http://www.ncbi.nlm.nih.gov/pubmed/25575520
(1277) http://www.ncbi.nlm.nih.gov/pubmed/23194526
(1278) http://www.ncbi.nlm.nih.gov/pubmed/24564587
(1279) http://www.ncbi.nlm.nih.gov/pubmed/24122196
(1280) http://www.ncbi.nlm.nih.gov/pubmed/22717023 
(1281) http://www.ncbi.nlm.nih.gov/pubmed/24989289
(1282) http://www.ncbi.nlm.nih.gov/pubmed/16868359
(1283) http://www.ncbi.nlm.nih.gov/pubmed/21376020
(1284) http://www.ncbi.nlm.nih.gov/pubmed/21166677
(1285) http://www.ncbi.nlm.nih.gov/pubmed/12165737
(1286) http://www.ncbi.nlm.nih.gov/pubmed/21728972
(1287) http://www.ncbi.nlm.nih.gov/pubmed/21499478
(1288) http://www.ncbi.nlm.nih.gov/pubmed/18844255
(1289) http://www.ncbi.nlm.nih.gov/pubmed/16842945
(1290) http://www.ncbi.nlm.nih.gov/pubmed/24519982
(1291) http://www.ncbi.nlm.nih.gov/pubmed/20061605
(1292) http://www.ncbi.nlm.nih.gov/pubmed/23713775
(1293) http://www.ncbi.nlm.nih.gov/pubmed/24134394
(1294) http://www.ncbi.nlm.nih.gov/pubmed/21728972
(1295) http://www.ncbi.nlm.nih.gov/pubmed/21166677
(1296) http://www.ncbi.nlm.nih.gov/pubmed/16842945
(1297) http://www.ncbi.nlm.nih.gov/pubmed/15934032
(1298) http://www.ncbi.nlm.nih.gov/pubmed/25640661
(1299) http://www.ncbi.nlm.nih.gov/pubmed/24262869
(1300) http://www.ncbi.nlm.nih.gov/pubmed/25546094
(1301) http://www.ncbi.nlm.nih.gov/pubmed/25506732
(1302) http://www.ncbi.nlm.nih.gov/pubmed/20083801
(1303) http://www.ncbi.nlm.nih.gov/pubmed/20603494
(1304) http://www.ncbi.nlm.nih.gov/pubmed/18032652
(1305) http://www.ncbi.nlm.nih.gov/pubmed/11295356
(1306) http://www.ncbi.nlm.nih.gov/pubmed/17380553
(1307) http://www.ncbi.nlm.nih.gov/pubmed/24134394
(1308) http://www.ncbi.nlm.nih.gov/pubmed/21376020
(1309) http://www.ncbi.nlm.nih.gov/pubmed/24579375
(1310) http://www.ncbi.nlm.nih.gov/pubmed/15087243

Wednesday, September 23, 2015

Easy cooking Recipes - . Vikie's Gazpacho Dip

Recipe contributed by Quick and easy family favorites by Vickie and JoAnn

Fresh summerflovors brust each scoop of this chunkydip. Tortilla chips are a good choice for dipping
3 tomatos, dices
3 avocados, peel, pitted, and diced
4 green onions, thinly sliced
4.5 Oz. can diced green chiles, undrained
3 T. olive oil
11/2 T. cider vinegar
1 t. garlic salt
1/4 pepper
Combined tomatos, avocados, onions and chiles in a large bowl; set asides, Whisk together olive oil and remaining 4 ingredients; drizzle over vegetable and toss well. Cover and chill. make 5 cups.

by Vicke, Gooseberry Patch

Weight Loss the Easy Ways

Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate

Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                      Diseases of Central Nervous system


                           Dementia


About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)

Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5.  According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
 C.5.1. Dementia due to toxins accumulation
Toxins accumulation in  internal organs disturbed the balance of immunity(1213)(1214) may cause  impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination 
1.  Shui Fei Zi or Milk thistle (Silybum marianum)
Shui fei zi, the bitter and cold is also known as milk thistle, native to Western Europe and northern Africa, used in traditional Chinese medicine to improve liver function(1193)(1194)(1210), promote the flow of breast milk(1207), bile secretion(1200), anti depression(1201) and anti tumors(1196)(1197)(1198), inhibit allergic effects(1195)(1199), treat hepatitis C(1202)(1203), cirrhosis(1205) and liver fibrosis(1206), by enhancing function of liver and gallbladder channels(1204)

Phytochemicals
 1. Flavonoid 
2. fumaric acid
3. Silymarin
 4. isosilybin, 
5. dehydrosilybin, 
6. silydianin and
7. silychristin. It also contains 
8. cinnamic acid, 
9. myristic acid, 
10. palmitelaidic acid, 
10. arachidic acid.  , 
11. palmitelaidic acid, 
13. Etc.  

Shui Fei Zi or Milk thistle used in the treatment and prevention of dementia(1218) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals Silymarin and Silibinin in ameliorated amyloid pathology(1216) and oxidative stress(1216)(1217) through attenuated levels of lipid peroxidation (malondialdehyde) and antioxidant (glutathione) in the hippocampus(1217).

1.1. In Alzheimer's disease
Alzheimer disease (AD). a neurodegenerative disorders is the most prevalent diseases  in the United States, in aging population(1219). Silymarin, a phytochemical found abundantly in milk thistle, in age related disorders like neurodegenerative diseases improved  locomotion rate, higher response to stimuli and tolerance to stress, in C.elegans Alzheimer's Model, through delayed paralysis via enhanced resistance to oxidative stress(1220). In rat induced Alzheimer's disease model, the phytochemical also inhibited amyloid formation(1222) and suppressed amyloid protein precursor (APP) expression(1222)and reduced neurotoxicity in PC12 cells(1222) in improvement memory(1223) and learning function(1221).

1.2. In Parkinson disease
In a mouse model of Parkinson's disease, causes od mitochondrial dysfunction and the selective cell death of dopaminergic neurons, silibinin, derivative of silymarin, protected mitochondria through attenuated motor deficit and dopaminergic neuronal loss(1224) and anti oxidative and anti inflammatory pathways(1225).


1.3. In neuroprotective effects  
In focal cerebral ischemia, silymarin (SM), a mixture of flavonolignans extracted from the milk thistle exerted it neuroprotective effects, in upregulating the antioxidant status and lowering the apoptotic response in slowing down the progression of neurodegeneration(1226) and preventing inflammation-related neurodegenerative disease(1227)  and ROS causing oxidative damage to macromolecules in the brain(1230).


1.4. In cognitive impairment
In cognitive deficit mice model, silibinin exhibited its anti cognitive impairment effects through amelioration of decreases in dopamine and serotonin levels in the prefrontal cortex and hippocampus, (1228). In amyloid beta peptide-induced memory impairment, the chemicals also improve cognitive memory deficits through attenuated the Abeta(25-35)- accumulation of malondialdehyde and depletion of glutathione in the hippocampus(1229).

2. Xiu Hui Xiang (Fennel)
Xiu Hui Xiang, the acrid and warm herb, is also known as fennel, native to Mediterranean, used in traditional Chinese medicine  as anti microbal(1232)(1233), antioxidant(1234)(1235) and emmenagogue(1236) and estrogenic(1244) and androgenic(1245) agents and to prevent bone loss in postmenopausal osteoporosis(1237)(1238), treat hepatic fibrosis(1239), gastro intestine disorder(1240)(1241), decrease hair thickness(1243) and increase flow of breast milk(1242) by enhancing function of liver, kidney, spleen, stomach channels(1231).

Phytoshemicals 1. Linoleic acid         
2. Palmitic acid  
3. Arachidic acid  
4. Behenic acid      
5. Quercetin  
6. Phytosteryl b-fructofuranoside  
7. 7-hydroxycoumarin 
8. 6,7-dihydroxycoumarin  
9. Oleanolic acid     
10. Sitosterol  
11. Fenchone 
12. α-pinene  
13. Limonene  
14. β-Pinene  
15. β-Myrcene  
16. α-Phellandrene  
17. P-Cymol  
18. Etc. 


Xiu Hui Xiang (Fennel) used in the treatment of symptoms of neurodegenerative disorder, including age-related mental problems of Alzheimer's disease(1246)) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals in acetylcholinesterase inhibition(1246) and anti inflammation(1247) through suppression of the nuclear factor-kappaB activation pathway(1247) involved stress, cell signaling, free radicals, oxidized LDL,activities(1248)(1249)(1250)(1251).

2.1. In anxiolytic activity
Anxiety is a condition of neurodisorder of unpleasant state of inner turmoil with fear of the presence and future, according to Diagnostic and Statistical Manual of Mental DisordersAmerican Psychiatric Association, effecting patients with dementia, including familial Alzheimer's disease(1252) and other neuropsychiatric disorders(1254). Fennel, a medical herb used in many cultures, have shown effectively in treating anxiety, epidemiologically. In adult Swiss albino male mice, oral administration 100 and 200 mg/kg doses of fennel essential oil significantly increased percent number of entries and time spent in open arms in elevated plus maze (EPM) test(1255).


2.2. In learning and memory
Fennels, the most widely used herbal plant in the world(1256) used in traditional Iranian medicine and modern phytotherapy for memory enhancing(1257).  In Alzheimer's disease, induced a decline of cognitive abilities in mice model, fennel extract successfully ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging- induced memory deficits in 8 days in dose-depend maner, through increased step-down latency and acetylcholinesterase inhibition(1258).

3. Da Suan(Garlic)
Da suan, the acrid, warm herb, is also known as garlic, native all over the world, used in traditional Chinese medicine as antibiotic(1259)(1260), anti aging(1261)(1262), anti cancers(1263)(1264)(1265), anti diabetic(1266)(1267), anti arterio-sclerosis anti platelet coagulation(1268)(1269) agents and treat to cardiovascular diseases(1270)(1271)(1272), lower blood pressure(1273)(1274),  blood lipids(1275)(1276)(1277) and promote immunity(1278)(1279)(1280) and capillary circulation(1281)(1282) by enhancing functions of large intestine, lung, spleen, stomach. channels(1258).

Phytochemicals
1.  Allyl methyl sulfide
2. Diallyl sulfide
3. 6-methyl-1-thio-2
4. 4-cyclohexadiene
5. Dimethyl sulfide
6. Divinyl sulfide
7. Dimethyl disulfide
8. Allyl methyl disulfide
9. Dithiocyclopentene
10. 5-methyl-1, 2-dithio-3-cyclopentene
 11.Allyl propyl disulfide
12. 4-methyl-1
13. 2-dithio-3-cyclopentene
14. Allyl propyl trisulfide 
15. Diallyl tetrasulfide
16. Dipropyl disulfide
17. Methyl propyl trisulfide
18. Allyl methyl tetrasulfide
19. Allyl methyl pentasulfide 
20. Etc. 


Da Suan(Garlic) used in the treatment of symptoms of dementia(1283)(1284)(1285), including Alzheimer's pathophysiology(1288)(1289) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals aged garlic extract and S-allyl-L-cysteine and extracts(1284) in oxidative stress inhibition(1284) and anti progression involved association of degeneration and neuro inflammatory activity(1286) through neuro protection against amyloid-beta peptide-induced apoptosis(1285) and toxicity(1287).

3.1. In Alzheimer's disease
Strong evidences suggested that deposited amyloid-beta(Abeta) has shown to associated to the progression in Alzheimer's disease (AD)(1290)(1291)(1292), In  mouse model induced by neurotoxic amyloid beta protein (Aβ), ethyl acetate fractions of garlic extract exhibited high levels of radical scavenging activity involved cognitive impairment against Aβ-induced neuronal deficit and  Aβ-induced learning and memory deficits in vivo(1293). According to Indiana University School of Medicine, the extracts also attenuated synaptic degeneration and neuroinflammatory pathways associated with AD, through major phytochemical S-allyl-L-cysteine (SAC) (1294), including oxidative insults to neurons(1295). In Alzheimer's transgenic model Tg2576, dietary aged garlic extract (AGE) (2%) showed to exhibited anti-amyloidogenic, anti-inflammatory and anti-tangle effects also through its phytochemicals S-allyl-cysteine (SAC) (20 mg/kg) and di-allyl-disulfide (DADS)(1296) without without interfering with its antibiotic activity in ameliorate gentamicin (GM)effectiveness(1297).

3.2. In Parkinson disease
 Olfactory dysfunction(1298)(1299) in non-motor functioning and hyposmia(1300)(1301)/anosmia(1302)(1303) are common manifestation in some neurodegenerative disorders caused by oxidative stress (OS) and inflammatory insults(1305), including Parkinson disease. Dietary supplement S-methyl-L-cysteine,  a substrate in the catalytic antioxidant system mediated by MSRA showed to protect cells from oxidative damage through its antioxidative effect(1304) when used conjunction with methionine sulfoxide reductase A in Parkinson's-like symptoms(1304).

3.3. In Cognitive impairment
In early cognitive deficits caused by gradually of accumulation of beta-amyloid peptide (Abeta) oligomers of Abeta42 species, aged garlic extract, in mice model, prevented progressive behavioral impairment, slowed  plaque development, through protection against deterioration of hippocampal based memory(1306), In Alzheimer's disease induced mice model, S-allyl cysteine, a component of aged garlic extract, ameliorated cognitive deficits and oxidative damage in the hippocampus of intracerebroventricular streptozotocin (ICV-STZ)(1308). According to Gyeongsang National University, the effectiveness of aged garlic extracts, in neurodegenerative disorders, notably Alzheimer's disease(AD), may be due to its antioxidant activities in improvement of cognitive impairment against Aβ-induced neuronal deficit(1307).

3.4. In learning and memory
Acute and chronic oral administration of aged garlic extract, in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze, improved learning and memory probably due to cortical acetylcholinesterase (AchE) and reduced glutathione (GSH) levels activities and anti-oxidant property(1309). In oxidative damage and spatial learning and memory deficits induced mice model, S-allylcysteine exerted its protective effect against reactive oxygen species. Abeta(25-35)-induced hippocampal toxicity and learning deficits, through its free radical  scavenging and ameliorated lipid peroxidation activities(1310).

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

For more research papers for dementia, please visit: Most Common Diseases of Elders at http://kylejnorton.blogspot.ca/p/dietary-vitamins.html


Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia - Treatments in Traditional Chinese Herbal Medicine by Kyle J. Norton  

References
(1193) http://www.ncbi.nlm.nih.gov/pubmed/9468229
(1194) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(1195) http://www.ncbi.nlm.nih.gov/pubmed/23121838
(1196) http://www.ncbi.nlm.nih.gov/pubmed/23879966
(1197) http://www.ncbi.nlm.nih.gov/pubmed/24574320
(1198) http://www.ncbi.nlm.nih.gov/pubmed/25242120
(1199) http://www.ncbi.nlm.nih.gov/pubmed/23701595
(1200) http://www.ncbi.nlm.nih.gov/pubmed/17692492
(1201) http://www.ncbi.nlm.nih.gov/pubmed/25431050
(1202) http://www.ncbi.nlm.nih.gov/pubmed/25247194
(1203) http://www.ncbi.nlm.nih.gov/pubmed/22797645
(1204)  http://alternativehealing.org/shui_fei_ji.htm
(1205) http://www.ncbi.nlm.nih.gov/pubmed/15277093
(1206) http://www.ncbi.nlm.nih.gov/pubmed/22087179
(1207) http://www.ncbi.nlm.nih.gov/pubmed/23468043 
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864 
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069 
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658 
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367 
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080 
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982 
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094 
(1216) http://www.ncbi.nlm.nih.gov/pubmed/21185897 
(1217) http://www.ncbi.nlm.nih.gov/pubmed/19552690 
(1218) http://www.ncbi.nlm.nih.gov/pubmed/21071836 
(1219) http://www.ncbi.nlm.nih.gov/pubmed/25696782
(1220) http://www.ncbi.nlm.nih.gov/pubmed/25613505
(1221) http://www.ncbi.nlm.nih.gov/pubmed/24460990
(1222) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1223) http://www.ncbi.nlm.nih.gov/pubmed/19638571
(1224) http://www.ncbi.nlm.nih.gov/pubmed/25677261
(1225) http://www.ncbi.nlm.nih.gov/pubmed/24660866
(1226) http://www.ncbi.nlm.nih.gov/pubmed/21840019
(1227) http://www.ncbi.nlm.nih.gov/pubmed/20833521
(1228) http://www.ncbi.nlm.nih.gov/pubmed/19857526
(1229) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1230) http://www.ncbi.nlm.nih.gov/pubmed/19647779
 (1231) http://alternativehealing.org/xiao_hui_xiang.htm
(1232) http://www.ncbi.nlm.nih.gov/pubmed/25384804
(1233) http://www.ncbi.nlm.nih.gov/pubmed/21462837
(1234) http://www.ncbi.nlm.nih.gov/pubmed/21812646
(1235) http://www.ncbi.nlm.nih.gov/pubmed/25143939
(1236) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+emmenagogue
(1237) http://www.ncbi.nlm.nih.gov/pubmed/22447109
(1238) http://www.ncbi.nlm.nih.gov/pubmed/25050267
(1239) http://www.ncbi.nlm.nih.gov/pubmed/22475144
(1240) http://www.ncbi.nlm.nih.gov/pubmed/22433535
(1241) http://www.ncbi.nlm.nih.gov/pubmed/20433751
(1242) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1243) http://www.ncbi.nlm.nih.gov/pubmed/24490010
(1244) http://www.ncbi.nlm.nih.gov/pubmed/6999244
(1245) http://www.ncbi.nlm.nih.gov/pubmed/13678227
(1246) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+dementia
(1247) http://www.ncbi.nlm.nih.gov/pubmed/15659827
(1248) http://www.nature.com/onc/journal/v25/n51/full/1209954a.html
(1249) http://link.springer.com/article/10.1385%2FCT%3A6%3A2%3A111
(1250) http://www.ncbi.nlm.nih.gov/pubmed/10602459
(1251) http://www.nature.com/nrm/journal/v8/n1/full/nrm2083.html
(1252) http://www.ncbi.nlm.nih.gov/pubmed/25688083
(1253) http://www.ncbi.nlm.nih.gov/pubmed/25687925
(1254) http://www.ncbi.nlm.nih.gov/pubmed/25653291
(1255) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+and+anxiety
(1256) http://www.ncbi.nlm.nih.gov/pubmed/25162032
(1257) http://www.ncbi.nlm.nih.gov/pubmed/23275017 
(1258) http://alternativehealing.org/garlic.htm
(1259) http://www.ncbi.nlm.nih.gov/pubmed/10594976
(1260) http://www.ncbi.nlm.nih.gov/pubmed/11759674
(1261) http://www.ncbi.nlm.nih.gov/pubmed/24066081
(1262) http://www.ncbi.nlm.nih.gov/pubmed/9131291
(1263) http://www.ncbi.nlm.nih.gov/pubmed/25078449
(1264) http://www.ncbi.nlm.nih.gov/pubmed/24859825
(1265) http://www.ncbi.nlm.nih.gov/pubmed/24309133
(1266) http://www.ncbi.nlm.nih.gov/pubmed/23543654
(1267) http://www.ncbi.nlm.nih.gov/pubmed/23923607
(1268) http://www.ncbi.nlm.nih.gov/pubmed/17918162
(1269) http://www.ncbi.nlm.nih.gov/pubmed/10192909
(1270) http://www.ncbi.nlm.nih.gov/pubmed/25141365
(1271) http://www.ncbi.nlm.nih.gov/pubmed/16484559
(1272) http://www.ncbi.nlm.nih.gov/pubmed/24067391
(1273) http://www.ncbi.nlm.nih.gov/pubmed/24172194
(1274) http://www.ncbi.nlm.nih.gov/pubmed/24199984
(1285) http://www.ncbi.nlm.nih.gov/pubmed/25671065
(1276) http://www.ncbi.nlm.nih.gov/pubmed/25575520
(1277) http://www.ncbi.nlm.nih.gov/pubmed/23194526
(1278) http://www.ncbi.nlm.nih.gov/pubmed/24564587
(1279) http://www.ncbi.nlm.nih.gov/pubmed/24122196
(1280) http://www.ncbi.nlm.nih.gov/pubmed/22717023 
(1281) http://www.ncbi.nlm.nih.gov/pubmed/24989289
(1282) http://www.ncbi.nlm.nih.gov/pubmed/16868359
(1283) http://www.ncbi.nlm.nih.gov/pubmed/21376020
(1284) http://www.ncbi.nlm.nih.gov/pubmed/21166677
(1285) http://www.ncbi.nlm.nih.gov/pubmed/12165737
(1286) http://www.ncbi.nlm.nih.gov/pubmed/21728972
(1287) http://www.ncbi.nlm.nih.gov/pubmed/21499478
(1288) http://www.ncbi.nlm.nih.gov/pubmed/18844255
(1289) http://www.ncbi.nlm.nih.gov/pubmed/16842945
(1290) http://www.ncbi.nlm.nih.gov/pubmed/24519982
(1291) http://www.ncbi.nlm.nih.gov/pubmed/20061605
(1292) http://www.ncbi.nlm.nih.gov/pubmed/23713775
(1293) http://www.ncbi.nlm.nih.gov/pubmed/24134394
(1294) http://www.ncbi.nlm.nih.gov/pubmed/21728972
(1295) http://www.ncbi.nlm.nih.gov/pubmed/21166677
(1296) http://www.ncbi.nlm.nih.gov/pubmed/16842945
(1297) http://www.ncbi.nlm.nih.gov/pubmed/15934032
(1298) http://www.ncbi.nlm.nih.gov/pubmed/25640661
(1299) http://www.ncbi.nlm.nih.gov/pubmed/24262869
(1300) http://www.ncbi.nlm.nih.gov/pubmed/25546094
(1301) http://www.ncbi.nlm.nih.gov/pubmed/25506732
(1302) http://www.ncbi.nlm.nih.gov/pubmed/20083801
(1303) http://www.ncbi.nlm.nih.gov/pubmed/20603494
(1304) http://www.ncbi.nlm.nih.gov/pubmed/18032652
(1305) http://www.ncbi.nlm.nih.gov/pubmed/11295356
(1306) http://www.ncbi.nlm.nih.gov/pubmed/17380553
(1307) http://www.ncbi.nlm.nih.gov/pubmed/24134394
(1308) http://www.ncbi.nlm.nih.gov/pubmed/21376020
(1309) http://www.ncbi.nlm.nih.gov/pubmed/24579375
(1310) http://www.ncbi.nlm.nih.gov/pubmed/15087243