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Thursday, June 30, 2016

Food therapy - Vegetables - Winter Squash (Cucurbita)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Squash (Cucurbita)

Squash is the genus Cucurbita, belongs to family Cucurbitaceae and native to Mexico and Central America. In North America, squash is divided into summer squash or winter squash, depending on the maturity of squash when harvested, immature fruit called summer squash and mature fruit called winter squash.

Winter Squash 
Difference from summer squash, it is harvested and eaten when the fruit is completely mature, the seeds within have matured fully and the skin has hardened into a tough rind. Winter squash can be stored for a long time and generally is cooked before eating.

Nutrients
1. Carbohydrate
2. Protein
3. Fat (Omega 3 fatty acid)
4. Dietary fiber
5. Calcium
6. Copper
7. Manganese
8. Magnesium
9. Potassium
10. Vitamin A
11. Vitamin B1
12. Vitamin B3
13. Vitamin B5
14. Vitamin B6
15. Folate
16. Vitamin C
17. Etc.

Health benefits
A. Health Benefits according to studies
1. Cell wall polysaccharides
In the investigation of Cell wall polysaccharides of 'Scarlet Warren' winter squash (Cucurbita maxima ) before and after thermal processing found that no difference was seen between raw and cooked samples. Likewise, the mobility of semimobile pectic polysaccharides was apparently unaltered by cooking. No change was detected in the rigid cellulose microfibrils on cooking, according to "Effects of cooking on the cell walls (dietary fiber) of 'Scarlet Warren' winter squash (Cucurbita maxima ) studied by polysaccharide linkage analysis and solid-state (13)C NMR" by Ratnayake RM, Sims IM, Newman RH, Melton LD.(a)

2. See above Summer squash studies
B. Health benefits according to concentration
1. Vitamin A
Vitamin A is not only important in preventing types I diabetes, according to "A close relationship between type 1 diabetes and vitamin A-deficiency and matrix metalloproteinase and hyaluronidase activities in skin tissues" byTakahashi N, Takasu S.(1) but also may be associated with compromised bone health, according to "Vitamins and bone health: beyond calcium and vitamin D" by Ahmadieh H, Arabi A.(2)

2. Vitamin C
a. Asthma
Vitamin C is one of the key antioxidant vitamins which is abundant in the extracellular fluid lining the lung and low vitamin C intake has been associated with pulmonary dysfunction, such as asthma, according to the study of "Vitamin Csupplementation for asthma" by Kaur B, Rowe BH, Arnold E.(3)

b. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.(4)

3. Dietary fiber
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(5)

4. Manganese
It is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(6) and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(7)

5. Etc.

C. Other health benefits
1. Vitamin B1
Vitamin B1 beside is important in functioning as a co-enzyme for production of energy, it also helps to prevent nervous tension and muscle abnormalities by decreasing the effect of Beriberi that cause confusion, muscle wasting, nerve problems and a rapid heartbeat, according to the article "Beriberi " posted in Wikipedia (http://en.wikipedia.org/wiki/Beriberi)

2. Vitamin B2
Riboflavin or vitamin B2 beside plays a significant role in the production of energy in carbohydrate metabolism, it also aid iron in the formation of fresh red blood cells and immune system in producing of antibodies in the body, accorsing to the study of "Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway" by


Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P Jr., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16386801)


3. Omega 3 fatty acid
Omega 3 fatty acid beside plays an vital role in lowering bad cholesterol (LDL) that reduces the risk of plague building up in the arterial wall, causing Coronary Artery Disease, (according to the study of "Omacor and Omega-3 Fatty Acids for Treatment of Coronary Artery Disease and the Pleiotropic Effects" by Kar S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21975796), it also balances the ratio of Omega 3 and 6 fatty acid that lessens the risk of the production of prostaglandin hormone, leading to menstrual abnormal cramps and pain, according to the study of "Herbal and dietary therapies for primary and secondary dysmenorrhoea" by Proctor ML, Murphy PA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed?term=Omega%203%20fatty%20acid%20and%20Cramps%20and%20pain)One small trial showed fish oil (omega-3 fatty acids), researchers wrote that to be more effective than placebo for pain relief. JAPANESE HERBAL COMBINATION: One small trial showed the herbal combination to be more effective for pain relief than placebo, and less additional pain medication was taken by the treatment group.

4. Folate
Folic acid beside is important for the production of red blood cells, and for the proper development of the brain and spine, according to the study of "Go folic!" by Bland J., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21853697) it also enhances the replication and maintenance of DNA and RNA., according to the study of "A folate- and methyl-deficient diet alters the expression of DNAmethyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats" by Ghoshal K, Li X, Datta J, Bai S, Pogribny I, Pogribny M, Huang Y, Young D, Jacob ST., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16702315)

5. Tryptophan
Tryptophan beside is an amino acid required by the human body to process proteins by producing serotonin which helps to enhance the brain in regulating appetite and mood. Some of the serotonin are converted to melatonin, which aids sleep patterns, according to the study of "Tryptophan increases nocturnal rest and affects melatonin and serotonin serum levels in old ringdove" by Paredes SD, Terrón MP, Cubero J, Valero V, Barriga C, Reiter RJ, Rodríguez AB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17222434)
6. Etc.

Side effect
1, Oxalates
Winter squash contains a measure amount of oxalates that can cause problem for some people who have untreated kidney and gallbladder diseases.
2. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/21604813
(1) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(2) http://www.ncbi.nlm.nih.gov/pubmed/21967159
(3) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(4) http://www.ncbi.nlm.nih.gov/pubmed/21986888
(5 http://www.ncbi.nlm.nih.gov/pubmed/20713332

(6) http://www.ncbi.nlm.nih.gov/pubmed/12870295
(7) http://www.ncbi.nlm.nih.gov/pubmed/22072339

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - E Jiao ( Colla Corrii Asini)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


              E Jiao ( Colla Corrii Asini)


E Jiao is also known as Donkey hide glue. The sweet and neutral herb has been used in TCM to treat chronic diarrhea, purpura, phobias, obsessions, compulsions, excessive anxiety, insomnia, bleeding of uterus, promote growth of children, etc. as it tonifies Blood, stops bleeding, nourishes Yin, moistens the Lungs, etc., by enhancing the functions of kidney, liver and lung channels.


Ingredients
1. Collagen
2. Lysine
3. Arginine
4. Histamine
5. Cysteine
6. Tryptophan
7. Hydroxyproline
8. Serine
9. Aspartic acid
10. Threonine
11. Glutamic acid
12. Proline,
13. Glycine
14. Alanine
15. Valine
16. Methionine
17. Isoleucine
18. Etc.

Health Benefits
1. Anemia caused by malignancy or chemotherapy
In the investigation of the effects of fractions A and B from enzyme-digested traditional Chinese medicine colla corii asini on mice with 5-fluorouracil-induced anemia, found that
This treatment significantly increased serum GM-CSF and EPO level and lowered serum transforming growth factor (TGF-beta) level. These results suggested that fractions A and B promoted hematopoiesis by activating immature granulocyte and erythroid cells, partly by stimulating GM-CSF and EPO secretion and suppressing TGF-beta release. Identification of a specific peptide or protein is still required for the development of a novel medicine for anemia caused by malignancy or chemotherapy, according to “Hematopoietic effect of fractions from the enzyme-digested colla corii asini on mice with 5-fluorouracil induced anemia” by Wu H, Yang F, Cui S, Qin Y, Liu J, Zhang Y.(1).

 2. Endotoxin shocks
In the assessment of the effects of Ejiao (Colla Corii Asini) on endotoxin shocks in dogs, found that Ejiao obviously suppresses the increase of blood viscosity during shocks, improves microcirculation, and recovers and stabilizes blood pressure rather quickly, according to “[Effects of Ejiao (colla corii asini) on the hemodynamics, hemorheology and microcirculation during endotoxin shock in dogs].[Article in Chinese]” by Yao DF, Zhang YF, Zhou YF.(2).

3. Etc.


Side Effects
1. Do not use the herb in case of blood stasis and spleen deficiency
2. Do not use E Jiao in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist
3. Do not use the herb if you have diarrhea
4. Etc.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/17963324
(2) http://www.ncbi.nlm.nih.gov/pubmed/2504192



Most Common Diseases of 50 Plus - Upper gastrointestinal disorders: Upper gastrointestinal bleeding - Treatments In conventional medicine perspective

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Upper gastrointestinal (GI) diseases

The prevalence of upper gastrointestinal (GI) diseases is increasing in subjects aged 65 years and over. Pathophysiological changes in esophageal functions that occur with aging may, at least in part, be responsible for the high prevalence of
1. Gastro-esophageal reflux disease (GERD) in old age.

2. The incidence of gastric and duodenal ulcers and their bleeding complications is increasing in old-aged populations worldwide.

3. H. pylori infection in elderly patients with H. pylori-associated peptic ulcer disease and severe chronic gastritis.

4. Almost 40% of GU and 25% of DU in the elderly patients are associated with the use of NSAID(1) and/or aspirin(2).(a)


         Upper gastrointestinal bleeding

Upper gastrointestinal bleeding (UGIB) is defined as hemorrhaging derived from a source proximal to the ligament of Treitz. It is life threatening and considered as medical emergency, which is followed by high mortality rate, ranging from 6 to 15% in spite of modern diagnostic methods and treatment. 
                The Treatments

 In conventional medicine perspective

Some researchers suggested that despite successful endoscopic therapy, rebleeding can occur in 10 to 20 percent of patients; a second attempt at endoscopic therapy is recommended in these patients. Arteriography with embolization or surgery may be needed if there is persistent and severe bleeding(16). Others indicated that Pre-endoscopic management (including use of scoring scales, nasogastric tube placement and blood pressure stabilization) is crucial for triage and optimal resuscitation of patients, and should include a multidisciplinary approach at an early stage. Unless the patient has specific comorbidities, transfusion should only be considered if their hemoglobin level is ≤70 g/l. Endoscopic therapy, the cornerstone of therapeutic management of high-risk lesions, should not be delayed for more than 24 h following admission. Several endoscopic techniques, mostly using clips or thermal methods, are available and new approaches are emerging. 

When endoscopy fails, surgery or arterial embolization should be considered. Although the efficacy of prokinetics and high-dose intravenous PPI prior to endoscopy is controversial, the use of an intravenous PPI following endoscopy is strongly recommended. Antiplatelet therapy should be suspended and resumed in 3-5 days. Finally, all patients should be tested for Helicobacter pylori by serology in the acute setting(21). 

Women Health: Fibroadenomas Prevention - How to avoid

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                            Fibroadenomas 

Fibroadenomas are benign breast tumors composed of fibrous and glandular tissue which occur mostly in women 30 years old or younger. According to statistic, approximately 500,000-700,000 fibroadenomas are removed each year in US alone. The benign breast tumors are also called breast mice or a breast mouse due to their high mobility in the breast. They are general painless and may become tenderness or swelling just before the menstrual cycle. women with multiple fibroadenomas may indicate a slightly increased risk of breast cancer.


              The Prevention - How to avoid


1. Avoid saturated and trans fat
Saturated and trans fat enhance the production of bad estrogen, which can increase the risk of the disease.

2. Avoid exposure to xanoestrogen
Same as above, exposure to xanoestrogen can increase the production of estrogen.

3. No refined sugar and artificial ingredients
Dieth igh in artificial ingredients and refined sugar can result in high estrogen production.

4. Oral contraceptive pill
In a study of risk factors for breast fibroadenoma in young women. Sitruk-Ware R, Thalabard JC, Benotmane A, Mauvais-Jarvis P., researchers found that Also current use of standard oral contraceptives (SOC) containing 50 micrograms of ethinyl estradiol per pill appeared to be protective and the correlation with FA was negative. These findings underline: (a) the predictive value of premenstrual mastalgia for the subsequent development of breast disease; (b) only current high-dose OC use is protective.

General Health: Depression - The Causes and Symptoms

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                Depression 


Depression is a normal response as part of our daily lives such as a loss of job,the death of a love one, and illness. Over 30 million Americans suffer from depression and the amount is increasing in an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself. In this article, we will discuss the causes and symptoms of depression.

                                  The Causes

1. Hormone imbalance
About 60% of people suffering from physical depression have abnormal levels of thyroid or adrenal hormones causing impaired thinking and making it difficult to carry out daily activity. If the thyroid hormone is in low levels we have hypothyroidism resulting in weight gain, fatigue and loss of appetite. If the thyroid hormone is in high levels we hyperthyroidism resulting in hand trembling, weakness, anxiety and nervousness
On the other hand, if adrenal hormone is in low levels symptoms may include stress, and weakness. If the adrenal hormone is in high level symptoms include weight gain, and diabetes.

2. Immune disorder
Immune system disorder causes concentration difficulty, lowered mood, memory loss, anxiety and symptoms of depression.

3. Nutritional deficiency
Too much Omega fatty 6 and deficiency of Omega acid 3 causes memory loss, mood swings and depression. On the other hand deficiency of vitamin B12, chromium, selenium or magnesium causes anxiety and depression as well as mood swings.

4. Sleeping disorder
If sleeping disorder is serious enough to interfere with normal physical, mental and emotional functioning such as fatigue, poor concentration, low mood and other symptoms of depression.

5.  Effect of medication taken
Many medications cause symptoms of depression as a side effect such as low mood and anxiety as a result of taking heart and hypertension medication.


                                                       The Symptoms

1. Loss of interest and energy in life
2. Change of sleeping and eating habits
3. Can not concentrate
4. Lowered self esteem
5. Deep sadness and hopeless
6. Thought of suicide and death
                

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: TCM Herbal Medicine for Kidney Yang deficiency -Di Huang

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).


Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into                

                           Kidney yang deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yang deficiency may also experience yang vacuity induced cold expressive syndrome, including
lumbago, cold limbs, fatigue, cold aversion, feverish sensation in chest, palms and soles(1573),
difficulty in urination, enuresis, incontinence, declining libido and edema(1574) as a result of kidneys no longer perform their function in store fluid to moister and warm the body for healthy function in the body's organs and tissues, inducing adrenal insufficient chronic lower back pain(1575)(1580), depression(1575), hypothyroidism(1579)(1575), nephritis(1578)(1575), ...(1575), leading to failure in transform damp heat expression, promoted accentuation of inflammatory development of phlegm(1583).
Kidney yang deficiency has shown to alter carbohydrate and lipid metabolisms (free fatty acids, 1-monolinoleoylglycerol, and cholesterol), gut microbiota metabolism (indole-3-propionic acid), indued anovulatory infertility( 1581) and hypertension(1582) of which related to symptoms of PCOs(1576)(1577).

Herbal medicine for kidney yang deficiency



3. Rehmannia glutinosa Liboschitz var. purpurae(Di Huang)
Di huang can be sheng (raw) or Shu (cooked) and is also known as Rehmannia

Sheng di huang(The bitter, sweet, bitter cold in nature) and Shu di huang (The bitter, sweet, bitter and warm in nature)(1724) has been used in TCM as diuretic(1734), anti hyperglycemicagent(1726), anti cancers(1731)(1732) and to treat cough(1743), asthma(1744)(1746), lung inflammation induced shortness of breath(1745), and wheezing(1746), tinnitus(1747) and hearing loss(17447), poor memory(1741), bronchial contraction)1746), and chest tightness(1746), lower plasma glucose(1725)(1727), enhance heart function(1734)(1735) (small doses constrict the blood vessels and large doses dilate the blood vessel)(1724), and regulate steroid hormone(1736),..... by promoting the functions of heart, kidney, and liver channels(1724).

Chemical constituents(1724)
1. Leonuride
2. Aucubin
3. Catalpol
4. Melittoside
5. Melittoside
6. Rehmannioside A、B、C、D
7. 8-epiloganic acid 8
8. Ajugoside
9. Lysine
10. Histidine
11. Arginine
12. Sapartic acid
13. Glutamic acid)
14. Threonine
15. Serine
16. Gluycine
17. Alanine
18. Valine
19. Isoleucine
20. Leucine
21. Tyrosine
22. Phenylalnine
23. Etc.


Epidemiological studies proposed that rehmannia also displays anti metabolic syndrome(1728), including fatigue(1728), prediabetes(1728)(1737), LDL-C, hypertension(1729), lipid profile(1728)(1737), including total cholesterol (TC), triglyceride (TG), high and low density lipoprotein cholesterol (HDL-C, LDL-C)(1736)(1737), insulin resistance(1730), waist size(1736) and obesity(1742), through its effects in carbohydrate(1740)(1741) and lipid metabolism(1728) of which reduce risk of diabetes(1728)(1739) and cardiovascular disease(1728)(1736).
According to Kyung Hee University. formula Kyung-Ok-Ko, containing rehmannia, prevented and alleviated dehydroepiandrosterone-induced polycystic ovarian syndrome in rats model(1738).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How ToPermanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) byLiqin Zhao

(1724) Di Huang(Complementary and Alternative Healing University)
(1725) Stachyose extract from Rehmannia glutinosa Libosch. to lower plasma glucose in normal and diabetic rats by oral administration by Zhang RX1, Jia ZP, Kong LY, Ma HP, Ren J, Li MX, Ge X.(PubMed)
(1726) Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism by Zhang R1, Zhou J, Jia Z, Zhang Y, Gu G.(PubMed)
(1727) Plasma glucose lowering mechanisms of catalpol, an active principle from roots of Rehmannia glutinosa, in streptozotocin-induced diabetic rats by Shieh JP1, Cheng KC, Chung HH, Kerh YF, Yeh CH, Cheng JT.(PubMed)
(1728) Evaluation of symptom, clinical chemistry and metabolomics profiles during Rehmannia six formula (R6) treatment: an integrated and personalized data analysis approach by van Wietmarschen HA1, van der Greef J, Schroën Y, Wang M.(PubMed)
(1729) The protective effect of Liu-Wei-Di-Huang-Fang in salt-sensitive hypertension rats byYang Q1, He Y, Wang W.(PubMed)
(1730) [Effect of Rehmannia glutinosa water extraction on insulin resistance and gene expression of resistin in type 2 diabetes mellitus rats]. [Article in Chinese] by Lv XF1, Meng QY, Guo XM.(PubMed)
(1731) Catalpol Inhibited the Proliferation of T24 Human Bladder Cancer Cells by Inducing Apoptosis Through the Blockade of Akt-Mediated Anti-apoptotic Signaling by Jin D1, Cao M, Mu X, Yang G, Xue W, Huang Y, Chen H.(PubMed)
(1732) Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells by Chao JC1, Chiang SW, Wang CC, Tsai YH, Wu MS.(PubMed)
(1733) Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats by Jang M1, Lee MJ1, Lee JM2, Bae CS3, Kim SH4, Ryu JH5, Cho IH6.(PubMed)
(1734) Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult byHuang C1, Cui Y, Ji L, Zhang W, Li R, Ma L, Xing W, Zhou H, Chen B, Yu J, Zhang H.(PubMed)
(1735) Saeng-Ji-Hwang has a protective effect on adriamycin-induced cytotoxicity in cardiac muscle cells by Chae HJ1, Kim HR, Kim DS, Woo ER, Cho YG, Chae SW.(PubMed)
(1736) [Effect of dandi tablet on blood lipids and sex hormones in women of postmenopausal stage]. [Article in Chinese] by Liang R1, Chen MR, Xu X.(PubMed)
(1737) Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice by Zhou J1, Xu G2, Yan J2, Li K2, Bai Z2, Cheng W2, Huang K3.(PubMed)
(1738) Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats by Jang M1, Lee MJ1, Lee JM2, Bae CS3, Kim SH4, Ryu JH5, Cho IH6.(PubMed)
(1739) Antidiabetic Effects of Carassius auratus Complex Formula in High Fat Diet Combined Streptozotocin-Induced Diabetic Mice by Wang ZH1, Hsu CC2, Lin HH3, Chen JH2.(PubMed)
(1740) Ameliorating effect and potential mechanism of Rehmannia glutinosa oligosaccharides on the impaired glucose metabolism in chronic stress rats fed with high-fat diet by Zhang R1, Zhou J2, Li M2, Ma H3, Qiu J2, Luo X4, Jia Z5.(PubMed)
(1741) d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol by Zhang XL1, An LJ, Bao YM, Wang JY, Jiang B.(PubMed)
(1742) Rehmannia inhibits adipocyte differentiation and adipogenesis by Jiang L1, Zhang NX, Mo W, Wan R, Ma CG, Li X, Gu YL, Yang XY, Tang QQ, Song HY.(PubMed)
(1743) The effect of a traditional Chinese prescription for a case of lung carcinoma by Kamei T1, Kumano H, Iwata K, Nariai Y, Matsumoto T.(PubMed)
(1744) The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma by Jung KH1, Choi HL2, Park S3, Lee G4, Kim M5, Min JK6, Min BI7, Bae H8.(PubMed)
(1745) [Shengdi injection on rat model of lung inflammation induced by lipopolysaccharides]. [Article in Chinese] by Liu L1, Tang L, Xu DS, Xia HL, Xie QM.(PubMed)
(1746) The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma by Jung KH1, Choi HL2, Park S3, Lee G4, Kim M5, Min JK6, Min BI7, Bae H8.(PubMed)
(1747) Rehmannia glutinosa activates intracellular antioxidant enzyme systems in mouse auditory cells by Yu HH1, Kim YH, Jung SY, Shin MK, Park RK, So HS, Kim KY, Lee DH, You YO.(PubMed)

The Obesity's Weight Loss Recipes - Toast pita chips

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Best Weight Loss and Healthy Recipe - Toast pita chips
Recipe contributed by 30 minutes vegetarian recipes by Marie-laude Morin, Publisher Robert Rose at www,robertrose.ca


This recipe can be served anywhere and anytime. The toasted iota points are a marvelous accompanied to hummus, guacamoles and dips.
Preheat over 400 degree F (200 degree C)
Baking sheet, lined with parchment paper.
4 pitas
Olive oil
Ground cumin
Paprika
1. Cut pitas into points. Place on prepared baking sheet. Brush with olive oil. Sprinkle with cumin and paprika to taste.
2. Bake in preheated oven for about 10 minutes or until bread is crispy. Let cool on pan on a wire rack. Serve 4.
Variation: Replace cumin and paprika with smoke paprika or your favorite dried herb for a different flavor.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Intermittent versus daily calorie restriction

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Intermittent versus daily calorie restriction

Dietary restriction is an effective strategy for weight loss in obese individuals.The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% of usual caloric intake every day. Another form of dietary restriction employed is intermittent CR, which involves 24 h of ad libitum food consumption alternated with 24 h of complete or partial food restriction. The study reveal that similar weight loss and fat mass loss with 3 to 12 weeks' intermittent CR (4-8%, 11-16%, respectively) and daily CR (5-8%, 10-20%, respectively). In contrast, less fat free mass was lost in response to intermittent CR versus daily CR.(1).

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Dong Kui Zi or Qing Ma Zi (Semen Malvae)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Dong Kui Zi or Qing Ma Zi (Semen Malvae)


Dong Kui Zi or Qing Ma Zi is also known as Cluster Mallow Fruit. The bitter, cold and with laxative property herb has been used in TCM to urinary tract infection, edema, constipation, dysentery, gonorrhea, boils, bronchitis, cystitis, and cataract, etc., as it calms urinary pain on urinary, promotes lactation, moistens the Intestines, etc., by enhancing the functions of large intestine, small intestine and bladder channels.


Ingredients
1. Protein
2. Anthocyanin
3. Monoa
4. Sucrose
5. Maltose
6. Etc.


Health Benefits
1. Antitumor activities
In the investigation of four short-term in vivo and in vitro tests were used to further confirm the antitumor activities of MCP, a vegetable powder, prepared from Malva crispa L. (i) In the H22 hepatoma-transplanting test, found that MCP had antitumor action, but MCP residue did not show such action, (ii) In the micronucleus (MN) test, MCP significantly decreased MN frequency. (iii) In the cancer cell culture systems, the MCP fat-soluble extract revealed inhibitory effects on the growth and proliferation of the human hepatoma and the gastric cancer cells in a dose-response manner. (iv) In the colony formation test, MCP also altered the morphology of human gastric cancer cells, according to “In vivo and in vitro studies on the antitumor activities of MCP (Malva crispa L. Powder)” by Huang CY, Zeng LF, He T, Wang CJ, Hong JR, Zhang XQ, Hou YH, Peng SS.(1)
2. Anti-complementary activity
In the assessment of the controlled Smith degradation of MVS-VI, the major acidic polysaccharide having remarkable anti-complementary activity isolated from the seeds of Malva verticillata L., found that the core structural features of MVS-VI include a backbone chain composed of beta-1,3-linked D-galactose residues. The majority of galactose units in the backbone carry side chains composed of beta-1,3- and beta-1,6-linked D-galactosyl residues at position 6. The controlled Smith degradation products showed considerable anti-complementary activity, according to “Constituents of the seed of Malva verticillata. VIII. Smith degradation of MVS-VI, the major acidic polysaccharide, and anti-complementary activity of products” by Tomoda M, Asahara H, Gonda R, Takada K.(2).

3. Anti-complementary and hypoglycemic activities
In the testing anti-complementary activity of seven polysaccharides and peptidoglycans obtained from the seeds of Malva verticillata were, found that mainly composed of beta-1,3-linked D-glucan and of alpha-1,5-linked L-arabino-beta-3,6-branched D-galactan, and the latter is essentially alpha-1,5-linked L-arabino-beta-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying alpha-1,3-linked L-arabinopyranosyl, beta-1,4-linked D-xylosyl, and alpha-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity, according to “Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata” by Tomoda M, Shimizu N, Gonda R, Kanari M, Yamada H, Hikino H.(3).

4. Mononuclear phagocyte (reticuloendothelial) system
In the assessment of an acidic polysaccharide, designated as MVS-IVA, isolated from the seeds of Malva verticillata, found that MVS-IVA showed a remarkable reticuloendothelial system potentiating activity in the carbon clearance test. Chemical and spectroscopic studies demonstrated that the polysaccharide is rich in alpha-L-arabinofuranose residues and possesses mainly an alpha-1,5-linked L-arabino-beta-3,6-branched-D-galactan structure accompanied with rhamnogalacturonan type units, according to “Characterization of an acidic polysaccharide from the seeds of Malva verticillata stimulating the phagocytic activity of cells of the RES” by Gonda R, Tomoda M, Shimizu N, Kanari M.(4).

5. Etc.

Side Effects
1. Do not use the herb in cause of qi or spleen deficiency with loose stool
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist

3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/10095926
(2) http://www.ncbi.nlm.nih.gov/pubmed/1423786
(3) http://www.ncbi.nlm.nih.gov/pubmed/2353063
(4) http://www.ncbi.nlm.nih.gov/pubmed/2141426

The Research and Studies of Skin Aging - The Effects of Herbal Medicine

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
All right reserved. Reproduction and Translation to other languages of this publication are prohibited without consent of the writer.

Who doesn't want to look 5, 10,15 or 20 years younger in comparison to people with the same age group?

The dream of finding the ingredients in rejuvenated aging skin has been ongoing since human civilization. Unfortunately, many ingredients with no commercial values have been discarded due to their effects in dampening the profits of all cosmetic companies.

Don't ask me about commercial anti-aging products. Most of them are produced for making profits and do not perform as theirs' claims. Truly, if one found to be effective, it will constitute to shelf-removal of many others with the same intention. Unfortunately, walking through the cosmetic section of health stores and super markets, thousands of these products are still packed on the shelves. How effective they are? You know the answer.

What cause aging? The question has been asked throughout the human history, but it doesn't seem to get any answer but raises many more unanswered questions. While many theories try to answer the question by related aging to tear and wear of the body, others deal with how the organs and systems in the body develop and deteriorate overtime, etc.

Skin aging is one of most visible process which occurs constantly in our skin organ. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals, to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin, affected skin elasticity and tightness(a). Other suggested that free radicals induced domino effects in production of reactive oxygen species, can react with DNA, proteins, and fatty acids, causing oxidative damage and impairment of antioxidant system, leading injuries damage regulation pathways of skin, including wrinkles, roughness, appearance of fine lines, lack of elasticity, and de- or hyperpigmentation marks(b).
The degradation of the epidermal and dermal layers of the extracellular matrix (ECM), the non-cellular component present within all tissues and organs, such as UV Exposure, decline of lysosomal/endosomal cathepsin K, S and V activity(c) as well as some environmental factors on skin produces visible signs such as irregular dryness, dark/light pigmentation, sallowness, severe atrophy, telangiectases, premalignant lesions, laxity, leathery appearance and deep wrinkling, etc., cause modification of the surface of skin and the physical properties of that lead to skin aging.
Certain chemical ingredients, such as aloin, ginsenoside, curcumin, epicatechin, asiaticoside, ziyuglycoside I, magnolol, gallic acid, hydroxychavicol, hydroxycinnamic acids, hydroxybenzoic acids, etc. derived from herbs have been found to be intergraded into some cosmetic products in treating premature aging(d)

1. Aloe vera
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.
In a study of a total of 30 healthy female subjects over the age of 45 recruited and received 2 different doses (low-dose: 1,200 mg/d, high-dose: 3,600 mg/d) of aloe vera gel supplementation for 90 days, aloe gel significantly improved wrinkles and elasticity in photoaged human skin, with an increase in collagen production in the photoprotected skin and a decrease in the collagen-degrading MMP-1 gene expression(1). In skin condition in the elderly caused by several incurable, but treatable, chronic diseases, researchers suggested that the use of lanolin, aloe vera, and parabens may contribute to delayed hypersensitivity reaction and aging process(2). In photo aging, combination of sodium selenite and aloin in a certain range of concentration have shown protective effects against ultraviolet radiation induced fibroblast proliferation inhibition, oxidative injury, and decreased collagen synthesis(3).

2. Green tea
Green tea containing more amount of antioxidants than any drinks or food with the same volume, is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
Oxidative damage by reactive oxygen species (ROS) plays a major role in skin aging. Green tea extracted showed to inhibit the toxic ROS-induced skin death, through protection from H(2)O(2)-induced necrosis in a dose-dependent manner(4)(4a), improvement of the anti-wrinkle effects, through its antioxidant activity(5), skin roughness, through moisturizing effects and enhancement of skinmicrorelief(6) and inhibition of skin inflammation for managing allergic contact dermatitis without skin toxicity(7). Combination of topical application of green teaand lotus, exhibited an anti aging effect on skin roughness (SEr), scaliness (SEsc), smoothness (SEsm), and wrinkling (SEw)(8) and composition of a formulation containing 20 % green tea extract and 5 % rose oil, exhibited a skinbarrier function for maintaining skin hydration, and protecting against anti-agingprocess(9).

3. Ginseng
Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belonging to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root). In vivo, Korean redginseng showed to enhance extension of lifespan, increase resistance to most forms of disease, through regulation of organisms' metabolism(10), and reduce wrinkle formation through
inhibition of collagen degradation rather than increased collagen synthesis(11), protect against skin photodamage, through increasing the production of profilaggrin and filaggrin(12). Ginsenoside Rd, a chemical constituent of Ginseng also exerted its anti-oxidative effects through activation of anti-oxidant enzymes and anti-inflammatory effects through down-regulation of NF-κB and the consequent expressional suppressions of iNOS and COX-2(13). On gene expression at the level of mRNAs and proteins in human skin cells, extracted from the roots of the Chinese herb Sanchi (Panax notoginseng, showed a significant positive effects against facial wrinkles and other symptoms of facial skin aging(14). In the study of red ginseng (RG) and fermented red ginseng (FRG) effects on aging skin, researchers at the Department of Food and Nutrition, Korea University found that FRG offers increased anti-wrinkle efficacy, whitening efficacy, and reduced toxicological potency compared to RG(15).

4. Turmeric
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
Curcumin, a major chemical compound found in turmeric, showed to have a protective effect against photo-damage on aging process(16). Antioxidantly, curcumin scavenged free radicals from skin cells, prevented trans-epidermal water loss, included a sun protection factor (SPF) of 15 or higher contribute to protectskin from wrinkles, leading to glowing and healthy younger skin(17) and induced cellular stress responses in normal human skin fibroblasts through phosphatidylinositol 3-kinase/Akt pathway and redox signaling(18).

5. Gotu Kola (Centella asiatica)
Gotu Kola also known as centella, is a annual plant of the genus, belonging to the family Mackinlayaceae, native to India, Sri Lanka, northern Australia, Indonesia, Iran, Malaysia, Melanesia, Papua New Guinea. The herb has been used in traditional medicine to treatnervous disorders, epilepsy, senility, premature aging, etc.
Asiatic acid, madecassic acid, asiaticoside and madecassoside, found in the titrated extract of Centella asiatica (TECA), showed to inhibit UVB-mediated damage in NHDFs through changes in the expression of specific miRNAs(19)(20). Preparation including asiaticoside found in Guto kota extract in a treatment of temporal periorbital wrinkles tested on 27 female volunteers by applied the cream twice a day to the region of interest for 12 weeks, showed a significant improvement of the periorbital wrinkles in majority of the volunteers(21). lipstick containing asiaticoside also found to improve lip-wrinkle in in a double-blind placebo-controlled fashion of a total of 50 women(22). According to 1LVMH Recherché, asiaticoside also stimulated collagen secretion which is the major components of skin dermis(23).

6. Sanguisorba officinalis
Sanguisorba officinalis is a genus Sanguisorba, belonging to the family Rosaceae, native to throughout the cooler regions of the Northern Hemisphere. The herb has been used in folk medicine to stop bloody dysentery, nosebleeds, and topically to treat burns and insect bites.
Ziyuglycoside I isolated from a Sanguisorba officinalis root extract reduced skin aging through increased the expression of type I collagen in a dose-dependent manner(24). In chronic Ultraviolet-B (UVB) irradiation causes of skin aging, the extract of Sanguisorba officinalis L. inhibited wrinkle formation, maintained skinelasticity, and inhibited the decrease of dermal elastic fiber linearity in the rat hind limb skin in a dose-dependent manner(25).

7. Magnolia ovovata
Magnolia ovovata also known as Japanese Bigleaf Magnolia is the genus of Ovovata, belonging to the familyMagnoliaceae, native to Japan. The herb has been used in traditional Chinese medicine
to treat various digestive problems, relieve stress, promote neuro-health, etc. According to

Nagoya City University Graduate School of Medical Sciences , Magnolia ovovata extract inhibited
NF-kappaB mediated gene expression, thus preventing skin photoaging processes through
keratinocyte hyperproliferation and degradation of collagen fibers in mice skin(26)(27).

8. Rhus verniciflua (Toxicodendron vernicifluum)
Rhus verniciflua is a genus Toxicodendron, belonging to the family Anacardiaceae, native to China
and the Indian subcontinent. The herb has been used in traditional Chinese medicine to treat internal
parasites and stop bleeding.
Rhus verniciflua Stokes (RVS), a most common used herbal plant in herbal medicine with various
biological properties was found to be effective in free radical scavengers due to contained flavonoid
derivatives, including fustin, quercetin, butein, and sulfuretin(29) which may protect the skin from
ROS aging. The ioactive phenolics in detoxified Rhus verniciflua Stokes (DRVS), including Gallic
acid showed to protect skin from aging through its antioxidative properties and by down-regulating
MMP-1 expression(28) and inhibited the degradation of extracellular matrix (ECM)(30).

9. Chamomile
Chamomile is also known as camomile, common name of many species daisy-like plants in the family Asteraceae. The herb has been used in traditional medicine as antispasmodic and anti-inflammatory
constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in
the bowels, relieve excessive gas and bloating in the intestine, etc.
Chemical compounds bisabolol, silymarin, and ectoin found in chamomile and milk thistle may consist
the property to modulate the hydrogen peroxide (H2O2)-induced upregulation of ROS free radicals in
normal human skin fibroblasts(31). According to University of Copenhagen, oral administartion of
composition extract including chamomile improved skin lession of forehead, periocular and perioral
wrinkles, mottled pigmentation, laxity, sagging, under eye dark circles and overall apperance(32).

10. Cinnamon
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species
of the genus Cinnamomum, belonging to the family Lauraceae. The herb has been use in herbal and
traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence
and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.
According to Osaka Prefecture University, Cinnamon inhibited the breakdown of collagenous networks with aging results in hypoactive changes in the skin, through up-regulated both mRNA and protein expression levels of type I collagen without cytotoxicity. Cinnamaldehyde, a major active component, significantly increased the phosphorylation levels of the insulin-like growth factor-I (IGF-I) and its downstream signaling molecules such as insulin receptor substrate-1 and Erk1/2 in an IGF-I-independent manner(33).

11. Ginkgo biloba
Ginkgo biloba is oldest living tree species, genus Ginkgo, belonging to the family Ginkgoaceae, native to China, and from temperate zone to subtropical zone and some parts of north America. It Has been used in traditional herbal medicine in treating impotence, memory loss,respiratory diseases, circulatory disorders and deafness as well as preventing drunkenness, and bedwetting.
The study in the comparison of ginkgo (Ginkgo biloba), a mixture of tea and rooibos (Camellia sinensis and Aspalathus linearis) and soybean (Glycine soja) for their effects in potentiation in reduced skin wrinkle, showed that ginkgo biloba, is most effective in increased skin moisturization (27.88%) and smoothness (4.32%) and reduced roughness (0.4%) and wrinkles (4.63%)(34).

12. Rosemary Rosemary is a perennial herb with fragrant, evergreen, needle-like leaves, the genus
Rosmarinus,
belonging to the family Lamiaceae. Its fresh and dried leaves has been used frequently in traditional
Mediterranean cuisine and as flavor foods while barbecuing. Rosnary has been used in traditional
medicine as an antiseptic, antioxidant, and antispasmodic agent to treat circulatory problem, eczema,
rheumatism, muscle pain, etc.
Rosemary containing flavonoid compounds with phenolic structures may potentiate in reduced reactive
oxygen species and biologic macromolecules, to neutralize free radicals or initiate biological effects to
prevent skin damage(35). According to University of Catania, natural extract isolated from rosemary
leaves, showed to be effective in antiaging skin management due to its endogenous antioxidant
potential(36).

14. Grape seed extract
Grape Seed Extract is the commercial extracts from whole grape seeds that contains many
concentrations, including vitamin E, flavonoids, linoleic acid, oligomeric proanthocyanidins(OPCs),
etc..The herb has been used in traditional medicine as antioxidant, anti-inflammatory agents and to treat
skin wounds with less scarring, allergies, macular degeneration, arthritis, enhance circulation of blood
vessels, lower cholesterol, etc.
Grape seed extract may be beneficial in promoting youthful skin, cell health, elasticity, and flexibility
because of its antioxidant effect to bond with collagen(37).
According to Dr. Bojanowski K., grape seed extract may have a potential in anti-aging effects
throughout all skin compartments, including dermal and epidermal layers because of its induced signal
transduction pathways in facial hypodermis(38). In a study of a total of men from 35 to 60 years of age,
phototypes I to III, indictaed a positive effect in counteract skin photoaging, in daily application of
mixture containing lycopene, acerola extract, grape seed extract and Biomarine ComplexT(39).

15. Lavender Lavender is a flower plant of the genus Lavandula, belonging to the family Lamiaceae,
native to Asia. The herb has been used in traditional medicine to treat painful bruises and aches,
to relieve various neuralgic pains, sprains, rheumatism, etc.
Suggestion of Lavender aromatherapy may potentiate to ease anxiety in patients undergoing minimally
invasive facial cosmetic procedures(40).
In photodegradation and photooxidation, chemical composition and bioactive properties of Lavandula
angustifolia Miller essential oil, used conjunction with bee oglue showed that bee glue expresses a
highly protected lavender oil secondary metabolites from degradation and also preserved their
antiradical properties, both in in vitro antioxidant assays and in cell oxidative damage evaluations(41).

16. Huang Qi (Radix astragali) Huang Qi or Bei Qi is also known as Astragalus root. The sweet herb
has been used as diuretic agent and to lower blood pressure, increase blood pressure, lessens
proteinuria, improve endurance, protect liver function, regulate blood sugar, etc. as it tonifies Qi,
raises Yang, strengthens the Defensive-Qi and the Exterior, expels toxins, etc. by enhancing the
functions of lung and spleen channels.
The study of non-fermented (HQNB) and fermented preparations (HQB) of Radix astragali on
hyaluronic acid (HA) production in primary human skin cells, showed that HQB significantly
stimulated HA production in both cultured primary human epidermal keratinocytes and human dermal
fibroblasts and increased the expression of hyaluronan synthase 3 and hyaluronan synthase 2 mRNA
in HaCaT cells and human fibroblasts, respectively in dose-dependent manners(42).

17. Puerariae Radix (Ge Gen)
Ge Gen is also known as Kudzuvine Root. The acrid, sweet and neutral herb has been used in TCM as anti-arrhythmia, anti cancers, anti-oxidation, anti platelet coagulation, etc. and to lower blood sugar,
relax the blood vessels, improve memory, treat diarrhea, etc., as it raises Yang; clears Heat,
promotes generation of Body Fluids, etc., by enhancing the functions of spleen and stomach channels.
The study of the effect of Puerariae Radix (PR), a Chinese herb and a popular food in Asia in
Hyaluronic acid (HA) concentrations in the intercellular spaces of the epidermis and the
connective tissues of the dermis, showed to stimulate the HA production of normal human epidermal
keratinocytes (NHEK), in dose-dependent, due to its rich in isoflavone glycosides like genistin and
daidzin(43).

20. Labisia pumila (Kacip Fatimah) Labisia pumila is the henus Lobisia, belonging to the family belongs
to the family of Myrsinaceae
native to in Southeast Asia, particularly Malaysia, Indonesia, Thailand, Laos, Cambodia, and Vietnam.
In skin aging, phytochemicals found in the herbal extract of Labisia pumila, protected against
natural aging process and accelerated by UV radiation through promoting the production of skin collagen
synthesis(43) and attenuation of UVB-induced MMP-9 expression in phtoaging(44).

Taken altogether, certain herbs have been found to enhance the protection of skin against natural
aging through protection in the degradation of epidermal and dermal layers of the extracellular
matrix (ECM), via their antioxidant and stimulative effects. Futher studies are necessary to identify
theirs effective ingredients to improve the clincal vadilation. As always all articles
written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.

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(13) Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver by Kim DH1, Chung JH, Yoon JS, Ha YM, Bae S, Lee EK, Jung KJ, Kim MS, Kim YJ, Kim MK, Chung HY.(PubMed)
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(23) [Comparative activity of asiaticoside and madecassoside on type I and III collagen synthesis by cultured human fibroblasts].[Article in French] by Bonté F1, Dumas M, Chaudagne C, Meybeck A.(PubMed)(24) Anti-wrinkle activity ofziyuglycoside I isolated from a Sanguisorba officinalis root extract and its application as a cosmeceutical ingredient by Kim YH1, Chung CB, Kim JG, Ko KI, Park SH, Kim JH, Eom SY, Kim YS, Hwang YI, Kim KH.(PubMed)
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(33) Cinnamon extract promotes type I collagen biosynthesis via activation of IGF-I signaling in human dermal fibroblasts by Takasao N1, Tsuji-Naito K, Ishikura S, Tamura A, Akagawa M.(PubMed)
(34) Clinical efficacy comparison of anti-wrinkle cosmetics containing herbal flavonoids by Chuarienthong P1, Lourith N, Leelapornpisid P.(PubMed)
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(36) Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology by Calabrese V1, Scapagnini G, Catalano C, Dinotta F, Geraci D, Morganti P.
(PubMed)
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(39)Clinical, biometric and ultrasound assessment of the effects of daily use of a nutraceutical composed of lycopene, acerola extract, grape seed extract and Biomarine Complex in photoaged human skin by Costa A1, Lindmark L, Arruda LH,Assumpção EC, Ota FS, Pereira Mde O, Langen SS.(PubMed)
(40) Effects of lavender olfactory input on cosmetic procedures by Grunebaum LD1, Murdock J, Castanedo-Tardan MP, Baumann LS.(PubMed)
(41) Biochemical Composition and Antioxidant Properties of Lavandula angustifolia Miller Essential Oil are Shielded by Propolis Against UV Radiations by Angelo G1, Lorena C, Marta G, Antonella C.(PubMed)
(42) Stimulating effects of Bacillus subtilis natto-fermented Radix astragali on hyaluronic acid production in human skin cells by Hsu MF1, Chiang BH.(PubMed)
(43) Comparison of Puerariae Radix and its hydrolysate on stimulation of hyaluronic acid production in NHEK cells by Wen KC1, Lin SP, Yu CP, Chiang HM.(PubMed)
(44) eview on Labisia pumila (Kacip Fatimah): bioactive phytochemicals and skincollagen synthesis promoting herb by Chua LS1, Lee SY, Abdullah N, Sarmidi MR.(PubMed)
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Women Health: Fibroadenomas - Symptoms, Causes and Risk Factors

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                        Fibroadenomas

Fibroadenomas are benign breast tumors composed of fibrous and glandular tissue which occur mostly in women 30 years old or younger. According to statistic, approximately 500,000-700,000 fibroadenomas are removed each year in US alone. The benign breast tumors are also called breast mice or a breast mouse due to their high mobility in the breast. They are general painless and may become tenderness or swelling just before the menstrual cycle. women with multiple fibroadenomas may indicate a slightly increased risk of breast cancer.


                 The Diagnosis and tests

After taking the family record and a careful physical examination, to look for any abnormal lumps in the breast, tests which your doctor may order include
1. Breast ultrasound
Ultrasound allows your doctor to visualize and assess the size of the fibroadenomas in your breasts and to check for any abnormality and surrounding area of the breasts with image taken from the test.
It may be difficult to interpret due to dense tissue. A biopsy of the breast may be necessary to rule out other disorders. Aspiration of the breast with a fine needle can often diagnose and treat Fibroadenomas.

2. Mammogram
Mammogram is a diagnostic and a screening tool with the use of low-energy-X-rays to examine the women breast tissue with the aim to detect any breast tissue abnormally and any sign of tumor. mammograms can detect between 85 to 90 percent of all abnormalities, including breast cancer, cysts, fibroadenomas, tumors, etc. even before you can feel a lump.

3. Breast biopsy
In breast biopsy, samples of affected abnormal area are taken by a thin, tube-like instrument to examine under microscopy to review the abnormalities.

Most Common Diseases of 50 Plus - Upper gastrointestinal disorders: Upper gastrointestinal bleeding - The Prevention

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Upper gastrointestinal (GI) diseases

The prevalence of upper gastrointestinal (GI) diseases is increasing in subjects aged 65 years and over. Pathophysiological changes in esophageal functions that occur with aging may, at least in part, be responsible for the high prevalence of
1. Gastro-esophageal reflux disease (GERD) in old age.

2. The incidence of gastric and duodenal ulcers and their bleeding complications is increasing in old-aged populations worldwide.

3. H. pylori infection in elderly patients with H. pylori-associated peptic ulcer disease and severe chronic gastritis.

4. Almost 40% of GU and 25% of DU in the elderly patients are associated with the use of NSAID(1) and/or aspirin(2).(a)


                Upper gastrointestinal bleeding 

Upper gastrointestinal bleeding (UGIB) is defined as hemorrhaging derived from a source proximal to the ligament of Treitz. It is life threatening and considered as medical emergency, which is followed by high mortality rate, ranging from 6 to 15% in spite of modern diagnostic methods and treatment.

                         The Prevention

1. Reduce stress
Stress-damage of upper gastro-intestinal tract (GIT) mucous membrane and gastro-intestinal hemorrhage (GIH)(17).
2. Cardiac surgery
GI bleeding events occurred approximately 10 days after cardiac surgery in patients with a complicated postoperative course. Improving the heart function is the best way to reduced risk of Upper gastrointestinal bleeding(18).
3. Drugs, alcohol and smoking
Chronic moderate alcohol consumption by itself does not seem to increase the liability to peptic ulceration. With highly concentrated alcoholic beverages, gastric bleeding from acute lesions may, however, be occasionally precipitated under certain circumstances, such as when unbuffered ASA is taken concomitantly. Smoking of cigarettes is associated, and perhaps causally related, with an increased incidence of gastric and duodenal ulcerations, impaired ulcer healing, and more frequent ulcer recurrences(19).
4. Avoid prolonged period intake of aspirin and medication which can induce Upper gastrointestinal bleeding (UGIB), such as Ibuprofen (Motrin, Advil)Naproxen (Anaprox, Naprosyn, Aleve)Ketoprofen (Orudis).
5. No extreme exercise
Gastrointestinal (GI) complaints are common among athletes with rates in the range of 30% to 70%. Both the intensity of sport and the type of sporting activity have been shown to be contributing factors in the development of GI symptoms. Three important factors have been postulated as contributing to the pathophysiology of GI complaints in athletes: mechanical forces, altered GI blood flow, and neuroendocrine changes. As a result of those factors, gastroesophageal reflux disease (GERD), nausea, vomiting, gastritis, peptic ulcers, GI bleeding, or exercise-related transient abdominal pain (ETAP) may develop(20).

6. Etc.