Monday, June 26, 2017

Thyroid hormone: Hereditary medullary thyroid carcinoma (HMTC)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

                                 Thyroid hormone



Thyroid hormone (triiodothyronine (T3) and thyroxine (T4)), produced by the thyroid gland, plays an important role in regulation of metabolism, including directly boosts energy metabolism and triggers rapid protein synthesis and regulates mitochondrial gene transcription, etc. Iodine is necessary for the production of T3and T4, deficiency of Iodine can lead to enlarge thyroid grand and goitre.


     Thyroid hormone: Hereditary medullary thyroid carcinoma (HMTC)


In the study to investigate the role of germline inheritance of polymorphisms in CYP1A2*F, CYP1A1m1, GSTP1, NAT2 and TP53 genes in hereditary medullarythyroid carcinoma (HMTC) patients of 132 patients with HMTC, 88 first-degree relatives of HMTC patients and 575 control individuals, found that
the inheritance of specific genes determining the individual response to environmental toxins may contribute to the risk and phenotypic variability that exists in patients with HMTC(59).





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