Adding a portion of carrots in women daily diet may have a profound and positive effect in reduced risk, progression and treatment of vulvar cancer, some scientists suggested.
The investigations were conduced by numbers of respectable university in women associated to higher risk of vulvar cancers, including the Tampere University Central Hospital and Mercer University and the results were published on online literature.
You can view the detail in abstracts of the studies by clicking any of the resources link
Vulvar cancer is a medical condition characterized by cell growth irregularly and disorderly in the tissue of the area of skin surrounded the urethra and vagina, including the clitoris and labia.
At the later stage, the cancerous cells may travel a distance away from the original site to infectious other healthy tissue.
The results of evaluation were reported by some respectable institutes and published on the online medical literature.
Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.
Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
In the study to analyze the association between body mass, selected indicator food intake, and vulvar cancer risk of 125 women aged 80 years or younger with histologically confirmed diagnosis of invasive vulvar cancer, admitted to a network of general and teaching hospitals in the greater Milan area in compared to Control subjects of 541 patients admitted to teaching and general hospitals in Milan for acute conditions, researcher found that carrot consumption is associated to reduce risk of the cancer.
In compared to others in exerted inconsistent association of risk of vulvar cancer such as milk, meat, liver, alcohol and coffee consumption, carrot demonstrated a significantly decreased risk ratio of 1.4.
The results suggest that certain factors in the dietary and nutritional aspects may process related mechanisms in risk of vulvar cancer.
Further analysis of carrot effect in risk of vulvar cancer inregard of the micro nutrients expression, researchers found that serum concentrations of vitamin A (retinol), vitamin E (alpha-tocopherol) and total carotene were lower in women with vulvar cancer but no difference to women with other types of female reproductive cancer such as cervical, endometrial and ovarian carcinomas.
In compared to healthy control, the mean levels of vitamin A was significantly less in patients with vulvar cancer.
However, according to the Mercer University, in analysis of the patients with metastasising carcinoma of the uterine cervix or recurrent disease after failure of surgical and/or radiation and chemotherapy therapy.
13-cis-retinoic acid and interferon alpha-2 a in the treatment of squamous cell carcinoma of the cervix in 6 patients with locally recurrent or metastasising squamous cell carcinomas, five of the uterine cervix, one of the vulva. in the period of 52 days, median survival time 107 days, filed the results as follows
* 3 women experienced progression of disease uninfluenced by therapy.
* 1 patient with multiple subcutaneous lymph node metastases showed mixed response for a short period of 3 weeks before progression and eventual death.
* 1 patient had no change or disease for 13 months with subsequent progression and eventual death after 22 months.
* One patient could not be evaluated for an allergic reaction after only 15 days of treatment.
The application also induced adverse effects of "flu-like symptoms", skin irritations, conjunctivitis sicca and chileitis, all WHO 1-2.
Overall toxicity is extremely low in compared to standard chemotherapy, but is not negligible.
The failure of study in treatment of advance vulvar cancer may be due to numbers of implication, researchers at the Mercer University suggested , "this might be due to the small number of cases, which is a common problem in immunotherapeutic studies. Moreover, very unfavourable patient selection criteria in our study compared to primarily untreated patients may also have contributed to different response rates. However, in our opinion the tested regimen cannot be considered sufficiently effective in patients suffering from pretreated, recurrent squamous cell carcinoma of the cervix or vulva".
Taken together, Carrot with high amount of nutrients and antioxidants may be used as functional food in reduced risk and combined with standard therapy for treatment of vulvar cancer. However, multi centers and large sample size studies are necessary to re confirm this viability.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) Selected food intake and risk of vulvar cancer by Parazzini F1, Moroni S, Negri E, La Vecchia C, Dal Pino D, Cavalleri E.(PubMed)
(2) Serum vitamins A and E and carotene in patients with gynecologic cancer by Heinonen PK1, Kuoppala T, Koskinen T, Punnonen R.(PubMed)
(3) [13-cis retinoic acid and interferon-alfa-2a as palliative therapy in pretreated, recurrent squamous epithelial carcinoma of the cervix uteri and vulva] by [Article in German](PubMed)
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