Chaste Tree Berry, the Best Functional Food for Treatment of Female Sex Hormone Deficiency

A renowned institute study suggested that Chaste tree berry may be a functional food for the treatment of female sex hormone deficiency.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

According to a joint study lead by the Ahvaz Jundishapur University of Medical Sciences, orally administrated Vitex agnus-castus fruit improved hypothalamic-pituitary-gonadal axis in the regulation of the reproductive system and immune system in free radical scavenger activities involved natural aging, in a d-galactose induced aging model in female mice.

Mice injected with d-galactose (500 mg/kg/d for 45 days) in seventy-two female NMRI mice (48 3-month-old normal mice and 24 18-24-month-old mice), weighing 30-35 g randomly divided into six groups: control, Vitex, d-galactose, Vitex + d-galactose, Aging, and Vitex + Aging, groups treated with Chaste tree berry or combination with herbal medicine showed a strong effect in increased the levels of malondialdehyde (MDA), follicle-stimulating hormone, and luteinizing hormone.


Dr. Ahangarpour A, the lead researcher said, " Vitex can be suitable for some aging problems such as oxidative stress, female sex hormone deficiency, and an atrophic endometrium".

Furthermore, the testing of flavonoid glycosides, orientin and apigenin 3, 8-di-C-glycosides and iridoid compound, aucubin isolated from the ethanolic extract of Vitex agnus-castus fruits, also showed a significant increase in plasma progesterone and total estrogens levels and reduction in luteinizing and plasma prolactin hormones in two dose levels 0.6 and 1.2 g kg(-1) per body weight (b.w.).



Additionally, the study also found that the ethanolic extract induced a significant increase in the uterine weight which showed an interaction of the sexual hormone of progesterone and estrogen of ovariectomized rats at two dose levels comparable to that of a control group.


Dr. Jillian Stansbury, not the author of the above studies said, "Consumption of Vitex fruits by female chimpanzees as part of their natural diets has been found to dramatically increase progesterone levels in the urine, indicating an overall progesterone effect.34 One hypothesis is that reduced LH allows the follicle-stimulating hormone to dominate and can lead to decreased estrogen and testosterone and a relative increase in progesterone".


Taking together, in women, Chaste Tree Berry may have a strong effect in influencing sex hormones
production in an expression of antioxidant, anti-aging, and normalized hormone activities.


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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Vitex agnus-castus fruit on sex hormones and antioxidant indices in a d-galactose-induced aging female mouse model by Ahangarpour A1, Najimi SA2, Farbood Y3.(PubMed)
(2) Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruitsgrowing in Egypt by Ibrahim NA1, Shalaby AS, Farag RS, Elbaroty GS, Nofal SM, Hassan EM.(PubMed)
(3) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury