Medical Advisor Journals

Monday, February 8, 2016

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Risk Factors and Diseases Associated to

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Restrictive lung diseases or restrictive ventilatory defects
Restrictive lung disease is a condition marked most obviously by a reduction in total lung capacity. A restrictive ventilatory defect may be caused by a pulmonary deficit, such as pulmonary fibrosis (abnormally stiff, non-compliant lungs), or by non-pulmonary deficits, including respiratory muscle weakness, paralysis, and deformity or rigidity of the chest wall(1).

The Risk Factors and Diseases Associated to

Risk factors
1. Second hand smoke and genetic influence
Cigarette smoke not only causes Respiratory Disease, including Restrictive lung disease but also can influence early immune function as a potential to interact with other genetic factors and environmental risk factors to influence disease propensity(10).
2. Obesity
Obesity, particularly severe central obesity, affects respiratory physiology both at rest and during exercise as a result of ventilatory defect due to reductions in expiratory reserve volume, functional residual capacity, respiratory system compliance and impaired respiratory system. In the study by National Taiwan University Hospital, showed that obesity may also impair upper airway mechanical function and neuromuscular strength, and increase oxygen consumption, which in turn, increase the work of breathing and impair ventilatory drive. The combination of ventilatory impairment, excess CO(2) production and reduced ventilatory drive predisposes obese individuals to obesity hypoventilation syndrome(11).
3. Race
African Americans are at higher risk than white race in development of Restrictive lung disease.
4. Age
As the disease is a result of progression over prolonged period of time, most patients with restrictive lung disease are older than 50 years.
5. Etc.

Diseases associated with restrictive lung diseases
1. Heart diseases
In the study to explore the association of COPD and restrictive lung function impairment, respectively, with heart diseases in the general population in a cross-sectional study of 642 randomly selected 22- to 72-year-old subjects in northern Swede, found that there is a strong association between COPD and cardiovascular diseases and indicates a strong association between restrictive lung function and heart diseases. Both obstructive and restrictive lung function impairments were common among subjects with heart diseases and vice versa(12).
2. Ulcerative colitis
There is an association between ulcerative colitis and lung disease in which patients have chronic cough and show hyperplastic and inflammatory changes in their bronchial mucosa, according to the study by
Guy’s Hospital and Brook General Hospital(13).
3. Syringomyelia and syringobulbia
There is a report of three patients with syringomyelia and syringobulbia who developed severe respiratory complications. In neurological examination showed evidence of IXth and Xth cranial nerve involvement with dysphagia and dysphonia, but there were no complaints of serious sleep difficulties. Two patients died during sleep and the other was resuscitated during a nap. All patients showed moderate restrictive ventilatory defects with reduced maximal buccal pressures and one also showed a low ventilatory response to CO2 rebreathing(14).
4. Sarcoidosis
In the study to assess various lung function indices, including C(L,s) and D(L,CO), as markers of functional abnormality in sarcoidosis patients from 830 consecutive patients referred for lung function tests with a diagnosis of sarcoidosis (223 in stage I, 486 in stage II and 121 in stage III), found that
Normal total lung capacity was found in 772 (93%) patients. Of these cases, 24.5% had a low C(L,s) and 21.5% had a low D(L,CO). At least one abnormality was observed in 39.3% of these patients, whereas, in restrictive patients, this figure was 88%. Airway obstruction was present in 11.7% of cases(15).
5. Neuromuscular disease
The earliest sign of respiratory compromise in the patient with neuromuscular disease is nocturnal hypoventilation, which progresses over time to include daytime hypoventilation and eventually the need for full-time mechanical ventilation(16).
6. Other diseases
According to the study by Department of Public Health and Clinical Medicine, Umeå University, in restrictive lung function the prevalence of chronic rhinitis, cardiovascular disease, hyperlipemia and diabetes was higher compared to in Nlf (41.0% vs 32.3%, p = 0.017, 59.0% vs 41.0%, p<0.001, 29.2% vs.12.9%, p = 0.033, 20.9% vs 8.6%, p <0.001). In COPD and heart disease, 62.5% had chronic rhinitis and/or GERD, while in Nlf the corresponding proportion was 42.5%(17).
7. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(11) http://www.ncbi.nlm.nih.gov/pubmed/22212441
(12) http://www.ncbi.nlm.nih.gov/pubmed/23127573
(13) http://thorax.bmj.com/content/35/8/581.full.pdf
(14) http://www.ncbi.nlm.nih.gov/pubmed/1640236
(15) http://www.ncbi.nlm.nih.gov/pubmed/20378598
(16) http://www.ncbi.nlm.nih.gov/pubmed/23137740
(17) http://www.ncbi.nlm.nih.gov/pubmed/22149402

The Curable of smoothie of Olive, Tomato and Carrot for prevention and treatment of Celiac disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for reduced risk and treatment of Celiac disease

Yield: 2 serving (about 8 ounce each)
1 1/4 cups tomatoes
1/4 cup olive
1 cup carrot juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Celiac disease has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Celiac disease is a condition of damaging the lining of the small intestine as a result of an autoimmune disorder. Some researchers indicated thesequence of alpha-gliadin (amino acids 31-49) is one of the triggers of the immune system in celiac spruewas because if its toxicity(1). Other suppose the theory of oxidative stress may play an important role in the progression of the disease(2).

Olive is belongings to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit a main source of olive oil., is also called the olive with abundant long chain ω-3 fatty acids, plant flavonoids and carotenoids(7) of which may play important role in treating patient with CD.

According to University of Pécs, n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) is associated to deficiency of Omega 3 fatty acids in patients with Celiac disease (CD(3).

The proper diet for CD caused by permanent intolerance to gluten/gliadin (prolamin)(4)may include the components of long chain ω-3 fatty acids, plant flavonoids, and carotenoids in modulation of oxidative stress, gene expression and production of inflammatory mediators(4)
Dr, Gmoshinskiĭ IVand Dr. Mazo VK. said," Fatty acids of the omega-3 and omega-6 series as well as histidine were found to change the permeability for the PEG-4000")(5) of that can reduce the risk of CD, if a therapy can alter the abnormally increased intestinal permeability(6).

Tomato with sources of lycopene, flavonoids and carotenoids is a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose and often in green house.

Other than the abnormally increased intestinal permeability, some researchers suggested additional relative risk to disease may also be due to abnormal epithelial cell infiltration by several lymphocyte subsets involved immune deficiency status such as pro inflammatory cytokines(9) of which can be controlled by lycopene, quercetin and tyrosol as non toxic agents involved in Celiac disease(8).

Dr. Cerf-Bensussan N. professor at the Université Paris Descartes said, "recent worrk indicates that dietary factors, including vitamin A and breast milk feeding, can protect against the development of harmful responses to dietary protein"(10) of that can be inporant in prevention of autoimmunity induced risk of CD.

Rich sources of Omega 3 fatty acids, lycopene, flavonoids and carotenoids from olive, tomato and carrot may hold a potential benefit for reduced risk and treatment of Celiac disease. The smoothie containing these ingredients in high amount should also mimic the similar effects in chronic use.
People at higher risk of Celiac disease due to genetic mutation causes of immune disorder should drink at least one serving daily and people with the disease should drink as much as they can, depending to the toleration of digestive system.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Identification of the triggers of celiac sprue by Saltzman JR1, Clifford BD(PubMed)

(2) Lycopene, quercetin and tyrosol prevent macrophage activation induced by gliadin and IFN-gamma by De Stefano D1, Maiuri MC, Simeon V, Grassia G, Soscia A, Cinelli MP, Carnuccio R(PubMed)

(3) Low n-3 long-chain polyunsaturated fatty acids in newly diagnosed celiac disease in children with preexisting type 1 diabetes mellitus by Tárnok A1, Marosvölgyi T, Szabó É, Györei E, Decsi T.(PubMed)
(4) Celiac disease, inflammation and oxidative damage: a nutrigenetic approach. by Ferretti G1, Bacchetti T, Masciangelo S, Saturni L.(PubMed)
(5) [Disordered permeability of the gastrointestinal tract barrier for macromolecules and the possibilities for its experimental dietetic correction].[Article in Russian] by Gmoshinskiĭ IV, Mazo VK.(PubMed)
(6) Alterations in intestinal permeability by M C Arrieta, L Bistritz, and J B Meddings(PubMed)
(7) Identification and quantitation of major carotenoids in selected components of the Mediterranean diet: green leafy vegetables, figs and olive oil by Su Q1, Rowley KG, Itsiopoulos C, O'Dea K.(PubMed)
(8) Lycopene, quercetin and tyrosol prevent macrophage activation induced by gliadin and IFN-gamma.by De Stefano D1, Maiuri MC, Simeon V, Grassia G, Soscia A, Cinelli MP, Carnuccio R.(PubMed)
(9) Natural polyphenols as anti-inflammatory agents. by Accomando S1, Pellitteri V, Corsello G.(PubMed)
(10) Autoimmunity and diet by Cerf-Bensussan N1.(PubMed)

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Causes

The Causes

The causes of restrictive lung disease are unknown but some researchers suggested the below
1. Cystic fibrosis
Recurrence is almost certainly more frequent in cystic fibrosis, and in view of the hazards of complication and the danger of bilateral pneumothoraces pleurodesis has to be considered. Of the various methods available, parietal pleurectomy is undoubtedly associated with the lowest incidence of
recurrence (Bromley, 1967; Heckscher, Larsen, and Lassen, 1966) and does not usually cause a restrictive ventilatory defect (Gobbel et al., 1963), so that provided the procedure is without undue risk it is the method of choice in this disease. In all three cases reported here there were severe obstructive
and restrictive defects of ventilatory capacity, but there were no immediate and serious post-operative complications, probably because of energetic physiotherapy and chemotherapy, according to the study by Brompton Hospital(5).
2. Cigarette smoke and air pollution
Welders exposed for over 10 years showed a prevalence of respiratory abnormalities significantly higher than those exposed for less than 10 years (44.4 vs 13.3%) (P less than 0.01) thereby showing that occupational exposure to welding fumes resulted in increased prevalence of pulmonary impairment in the welders. Smoking also had a contributory role thereby suggesting an interaction between smoking and welding exposure on the prevalence of pulmonary impairment in the welders engaged in brassware industries(6). Other suggested that in the study to investigate symptomatology, lung function, and radiographic change over an average period of 8 to 9 yr, of Sixty-four subjects with asbestos-related diffuse pleural thickening attending the London Medical Boarding Centre for Respiratory Diseases, showed that Chest pain was a common symptom, occurring in over half of the subjects. Approximately one-third of the subjects had a history of pleurisy or pleural effusion. Full long function, available in all cases, showed a highly significant decrement (p < 0.001) compared with predicted values in all variables except gas transfer coefficient (Kco) at initial presentation, consistent with a restrictive ventilatory defect(7).
3. Osteogenesis imperfecta (OI)
Osteogenesis imperfecta (OI) is an inherited connective tissue disorder characterized by bone fragility, multiple fractures and significant chest wall deformities. In the study of seven patients with severe OI type III, 15 with moderate OI type IV and 26 healthy subjects, found that the restrictive respiratory pattern of Osteogenesis Imperfecta is closely related to the severity of the disease and to the sternal deformities. Pectus carinatum characterizes OI type III patients and alters respiratory muscles coordination, leading to chest wall and rib cage distortions and an inefficient ventilator pattern. OI type IV is characterized by lower alterations in the respiratory function(8).
4. Connective tissue diseases
In the study to perform PFT in rheumatoid arthritic patients without pulmonary involvement and to identify variables related to changes in PFT over 5 years of follow-up in 82 patients (21 men, 61 women), found that among the 67 surviving patients, 38 (56.7%) agreed to participate in a follow-up study. The initial PFT revealed normal PFT in only 30 patients (36.6%); an obstructive ventilatory defect in 2 (2.4%), a small airway defect in 12 (17%), a restrictive ventilatory defect in 21 (25.6%), and reduced DLco in 17 (20.7%). Among the 38 patients participating in the 5 year follow-up study, 8 developed respiratory symptoms, one patient had a new obstructive ventilatory defect, one patient developed a restrictive ventilatory defect, and 5 patients had a newly developed small airway defect(9).
5. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(4) http://www.ncbi.nlm.nih.gov/pubmed/8542134
(5) http://thorax.bmj.com/content/25/2/165.full.pdf
(6) http://www.ncbi.nlm.nih.gov/pubmed/1915188
(7) http://www.ncbi.nlm.nih.gov/pubmed/8542134
(8) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338769/
(9) http://www.ncbi.nlm.nih.gov/pubmed/19432035

Sunday, February 7, 2016

The Delicious and Simple Kiwifruit, Avocado and Grape for reduced risk and treatment of Insomnia

1/2 cup banana
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of insomnia is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent studies suggested that combination of kiwifruit(1) may hold a key of ingredients for reduced the risk and treatment of sleep disorder, particular insomnia.

Insomnia is a sign and symptom of sleep disorder and defined as a condition in which a person has a difficulty falling asleep and/or staying asleep or sleep of poor quality that can lead to substantial impairments in the quality of life and functional capacity of an individual. Most adults have experienced insomnia sometimes in their life. According to statistic, more than 30% of the population suffers from insomnia, one in three people suffer from some form of insomnia during their lifetime and women suffer from insomnia more often than men.

Kiwifruit also best hnown as kiwi or Chinese gooseberry, is a species of A. chinensis belong to the family Actinidia, subgroup of the flavonoids and native to Southern China.

According to the Taipei Medical Uni-versity, kiwifruit consumption showed to improve sleep onset, duration, and efficiency in adults after 4 weeks(1).Also in animal study, Oral administration (125-1000mg/kg) of green (GRPE, Actinidia deliciosa) and gold (GOPE, Actinidia chinensis) induced decrease in sleep latency and an increase in sleep duration in pentobarbital-treated mice in a dose-dependent manner(2).

Melatonin intake can improve sleep quality, pain and pain threshold. According to the study by the Universidade Federal do Rio Grande do Sul (UFRGS) in comparison with amitriptyline suggested that melatonin reduced significantly pain on pain score on the Visual Analog Scale compared with amitriptyline alone, through increased the inhibitory endogenous pain-modulating system(4)

In a clinical crossover study of 30 healthy volunteers consumed selected fruits one at a time, with a 1 week wash-out period between fruits, until completing all six fruits showed that consumption of some tropical fruits have significant effects on melatonin production(5).

Dr. Lyseng-Williamson KA in the assessement of aging and insomnia said." melatonin PR 2 mg 1-2 h before bedtime was associated with significant improvements relative to placebo in many sleep and daytime parameters, including sleepquality and latency, morning alertness and health-related quality of life"(3).

Pineapple is a species of Ananas Comos. belong to the family Bromeliaceae and native to southern Brazil and Paraguay. Today it is widely cultivated for commercial and its rich of vitamins and mineral and digesting enzyme bromelin which seems to help digestion at the end of a high protein meal. It is second only to banana as America's most favourite tropical fruit

Dr. Johns NP and colleagues at the Khon Kaen University said," selected fruits(pineapple, orange and banana) consumption may reduce age-related melatonin reduction problems such as sleeplessness and illnesses involving oxidative damage"(6).

Orange is a species of Citrus Sinensis, belong to the family Rutaceae and native to the Southeast Asia. Orange is round citrus fruits with finely-textured skins, orange in color and one of most popular fruits in the world.

The increased levels of melatonin content during alcoholic fermentation of orange juice may hold a key to attenuate the melatonin due to ageing(7).

Dr. Huang X and Dr. Mazza G. said," orange had the highest melatonin content" in the the direct analysis of initial methanol extracts was compared with further ethyl acetate extraction(8).

Taking altogether, intake of combination of pineapple, orange, banana and kiwifruit induced the production of melatonin of that improved the sleep pattern and reduced significantly pain on pain score may be beneficiary for treatment of insomnia.

People who are at risk of insomnia due to aging may drink one or 2 servings a day, people with

insomnia should drink as much as they can, depending to the digestive alternation.

References

(1) Effect of kiwifruit consumption on sleep quality in adults with sleep problems by Lin HH1, Tsai PS, Fang SC, Liu JF.(PubMed)

(2) Green and gold kiwifruit peel ethanol extracts potentiate pentobarbital-induced sleep in mice via a GABAergic mechanism by Yang H1, Lee YC, Han KS, Singh H, Yoon M, Park JH, Cho CW, Cho S.(PubMed)

(3) Melatonin prolonged release: in the treatment of insomnia in patients aged ≥55 years by Lyseng-Williamson KA1(PubMed)
(4) Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system infibromyalgia: a phase II, randomized, double-dummy, controlled trial BY de Zanette SA, Vercelino R, Laste G, Rozisky JR, Schwertner A, Machado CB, Xavier F, de Souza IC, Deitos A, Torres IL, Caumo W1.(PubMed)

(5) Use of complementary and alternative medical therapies by patients referred to a fibromyalgia treatment program at a tertiary care center by Wahner-Roedler DL1, Elkin PL, Vincent A, Thompson JM, Oh TH, Loehrer LL, Mandrekar JN, Bauer BA(PubMed)
(6) Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers by Johns NP1, Johns J, Porasuphatana S, Plaimee P, Sae-Teaw M.(PubMed)
(7) Alcoholic fermentation induces melatonin synthesis in orange juice by Fernández-Pachón MS1, Medina S, Herrero-Martín G, Cerrillo I, Berná G, Escudero-López B, Ferreres F, Martín F, García-Parrilla MC, Gil-Izquierdo A.(PubMed)
(8) Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry by Huang X1, Mazza G.(PubMed)

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Symptoms

The Symptoms

1. Dyspnea (shortness of breath)
Patients with obstructive and restrictive ventilatory abnormalities suffer from exercise intolerance and dyspnea. Breathing pattern components (volume, flow, and timing) during incremental exercise may provide further insight in the role played by dynamic hyperinflation in the genesis of dyspnea parameters(2).
2. Wheezing
Wheezing occurs during breathing, as a result of some parts of the respiratory tree must be narrowed or obstructed due to inflammation of the airways expiration causes of a blockage in the airways or lungs.
3. Chronic coughing
Chronic cought is a insistently repetitive or continuous cough last longer than eight weeks.
According to the study of 10 patients with ulcerative colitis, all of whom were non-smokers, presented with a productive cough. In six, the chest radiograph was normal and cough was the only symptom; three of these patients had a minor obstructive ventilatory defect on testing. Four patients complained
of exertional dyspnoea and had both an abnormal chest radiograph with bilateral pulmonary shadows and a mixed obstructive and restrictive ventilatory defect(3).
4. Coughing up blood
It may be a result due to bleeding of the upper Respiratory tract or lung tumor.
5. Chest pain
Half of patients with respiratory Diseases are experience symptoms of chest pain(4).
6. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(2) http://www.ncbi.nlm.nih.gov/pubmed/15080225
(3) http://thorax.bmj.com/content/35/8/581.full.pdf

Friday, February 5, 2016

The Fascinate and Curable smoothie of Green Tea, Tomato and Blueberry for Prevention and Treatment of Cataract

Kyle J. Norton(Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Cataract

Yield: 2 serving (about 8 ounce each)
1 1/2 cups grape
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place tall ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Cataract with no adverse effects has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Cataract is an aging eye disorder of clouding of the lens, causing the reduction of one vision.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemical (-)-epigallocatechin gallate (EGCG), attenuate the oxidative stress causes of proteins presented in ocular lens of that related to the development of cataract(1).

In cultured human lens epithelial cells under hyperglycemia, (-)-Epigallocatechin gallate (EGCG), exhibited the potential protective effect against diabetic cataract formation in against the HLEB-3 cells from high glucose-induced apoptosis(2).
In diabetic cataracts, with green and black teas given at 1.25% in the drinking water to streptozotocin-induced diabetic rats for 3 months, Dr. Vinson JA and Dr. Zhang J. said," teas retard the development of diabetic cataracts by a hypoglycemic effect that in turn inhibits the biochemical indicators of pathology"(3).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. Its major sources of phytochemical and vitamin is associated to reduce risk for cataract(4).

Carotenoids, another major constituents in tomato, in a total of 1802 women aged 50 to 79 years in Iowa, Wisconsin, and Oregon expressed a 23% lower prevalence of nuclear cataract in older women(5).

Dr, Christen WG and colleagues at the Harvard Medical School, in a study of in 39,876 female health professionals said, " higher dietary intakes of lutein/zeaxanthin and vitamin E from food and supplements were associated with significantly decreased risks of cataract."(6).

Resveratrol, a dominant compound found in blue berry also exhibited protective effect on lens epithelial cell apoptosis in diabetic cataract rat(7) and long-term diabetic complications causes of diabetic cataract(8).

The antioxidant also exerted strong anti oxidative stress-related lenticular disorders such as cataract formation in either physiologic (5%) or chronic hyperoxic (40%) oxygen conditions(9), according to the Duke University Medical Center.

The discovery of the combination of Green Tea, Tomato and Blueberry through pre clinical trial and studies may form a cornerstone for production of a natural and curable in prevention and treatment of cataract in aging population without inducing adverse effects.

People who are at higher risk to develop cataract due to aging, chronic illness should drink at least 2 servings daily. Elderly with the disease should drink the smoothie as much as they can, depending to digestive and liver toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) EGCG prevents tryptophan oxidation of cataractous ocular lens human γ-crystallin in presence of H2O2 by Chaudhury S1, Ghosh I1, Saha G2, Dasgupta S3(PubMed)

(2) [(-)-Epigallocatechin gallate regulates expression of apoptotic genes and protects cultured human lens epithelial cells under hyperglycemia].[Article in Russian] by Ye P, Lin K, Li Z, Liu J, Yao K, Xu W.(PubMed)

(3) Black and green teas equally inhibit diabetic cataracts in a streptozotocin-induced rat model of diabetes by Vinson JA1, Zhang J.(PubMed)

(4) Association of vitamin A and β-carotene with risk for age-related cataract: a meta-analysis by Wang A1, Han J2, Jiang Y2, Zhang D3.(PubMed)

(5) Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in theCarotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health Initiative by Moeller SM, Voland R, Tinker L, Blodi BA, Klein ML, Gehrs KM, Johnson EJ, Snodderly DM, Wallace RB, Chappell RJ, Parekh N, Ritenbaugh C, Mares JA;CAREDS Study Group; Women's Helath Initiative.(PubMed)

(6) Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study by Christen WG1, Liu S, Glynn RJ, Gaziano JM, Buring JE.(PubMed)

(7) Protective effect of resveratrol on lens epithelial cell apoptosis in diabetic cataract rat by Wang HM1, Li GX2, Zheng HS3, Wu XZ3.(PubMed)

(8) Therapeutic potential of resveratrol in diabetic complications: In vitro and in vivo studies by Ciddi V1, Dodda D2.(PubMed)

(9) Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity by Li G1, Luna C, Navarro ID, Epstein DL, Huang W, Gonzalez P, Challa P.(PubMed)

Most Common Diseases of elder: Chronic obstructive pulmonary disease (COPD) (Respiratory Disease): Treatment In traditional Chinese medicine perspective

Respiratory Disease
Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Chronic obstructive pulmonary disease (COPD))is the third leading cause of death in the United State.

Types of Chronic obstructive pulmonary disease (COPD)

1. Emphysema, a type of Chronic obstructive pulmonary disease (COPD), is defined as a long term and progressive condition cause of shortness of breath but depending to the stage of lung function as a result of damage to tissues of the air sacs (alveoli) in the lungs. In the study of 63 patients with stable COPD (spirometric GOLD stages 2–4) and 17 age- and comorbidity-matched controls, researchers found that in contrast to asthma, COPD is characterised by elevated concentrations of both BDNF and TGF-beta1 in serum. The stage-dependent association with lung function supports the hypothesis that these platelet mediators may play a role in the pathogenesis of COPD(1). In some cases, but rarely, Emphysema is caused by Alpha-1 antitrypsin deficiency emphysema.

2. Chronic bronchitis
Chronic bronchitis is a chronic inflammation of the lung’s bronchi cause of the increased production of mucus in the lung of that leading to difficult breathing.

The Treatment

F.3. In traditional Chinese medicine perspective
Transitional Chinese medicine defined chronic obstructive pulmonary disease (COPD) is a result of smoking and air pollution causes of lung Yin deficiency (With symptoms of dry cough) at the beginning. If the disease is left untreated, it can cause accumulation of heat in the lung (with dry cough begins to produce sticky sputum), leading to the development of phlegm. Prolonged period of phlegm accumulation can obstruct the lung, causing lung Qi deficiency(56). In a prospective, multi-center, double-blinded and randomized controlled method used to test the therapeutic effects of TCM treatment according to syndrome differentiation of a total of 504 patientsenrolled into this study with 252 in each treatment group, showed that patients with COPD will benefit from therapy with TCM treatment according to syndrome differentiation(57).

1. Bu-Fei Jian-Pi granules, Bu-Fei Yi-Shen granules and Yi-Qi Zi-Shen granules
In the study to evaluate the efficacy and safety of the comprehensive therapy based on the three common TCM patterns in stable COPD patients, conducted by The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, found that based on the TCM patterns, Bu-Fei Jian-Pi granules, Bu-Fei Yi-Shen granules and Yi-Qi Zi-Shen granules have beneficial effects on measured outcomes in stable COPD patients over the 6-month treatment and 12-month follow-up, with no relevant between-group differences in adverse events(58).

2. Bu-Fei Yi-Shen granule combined with acupoint sticking therapy
In the study to evaluate the efficacy and safety of traditional Chinese herbal medicine, the Bu-Fei Yi-Shen granule combined with acupoint sticking therapy in patients with stable COPD. found that Bu-Fei Yi-Shen granule combined with acupoint sticking therapy showed beneficial effects for patients with stable COPD in the measured parameters over the 4-month treatment period and 6 months follow-up, with no relevant between-group differences in adverse events(59).

3. Warm needling therapy
In the study to observe the effects on chronic obstructive pulmonary disease (COPD) in the stable phase treated with warm needling therapy and Seretide and make the comparison of improvements between two therapies in terms of the clinical symptoms and life quality, found that Warm needling therapy improves the pulmonary function of the patients with COPD in the stable phase, releases clinical symptoms and improves life quality. Its effects are similar to those of Seretide(60).

4. Tanreqing injection
In the study to explore the effects of Tanreqing injection, a traditional Chinese herbal preparation for clearing heat and resolving phlegm, in treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) by improving airway inflammation and airway mucus hypersecretion, researchers at the West China Hospital, Sichuan University found that Tanreqing injection can improve TCM signs and symptoms in AECOPD patients, and the mechanism maybe due to the decrease of serum levels of IL-8 and NE and improvement of IL-10 level(61).

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Sources
(1) http://respiratory-research.com/content/13/1/116/abstract
(57) http://www.ncbi.nlm.nih.gov/pubmed/22799753
(58) http://www.ncbi.nlm.nih.gov/pubmed/23107470
(59) http://www.ncbi.nlm.nih.gov/pubmed/21911051
(60) http://www.ncbi.nlm.nih.gov/pubmed/22043675
(61) http://www.ncbi.nlm.nih.gov/pubmed/18664347