The Smoothie of formula RRF and Flax Seed for Reduced Symptoms and Treatment of Perimenopause

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced symptoms and treatment of Perimenopause 
Yield: 2 serving (about 8 ounce each)
1 gram of formula RRF(you cam buy them in any Chinese herbal store)
1/2 cup of flax seed
1 cup of grape
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced symptoms and treatment of Perimenopause  is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potentials in large sample size and multi center.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, from Radix Astragali (RA), Radix Angelicae Sinensis (RAS) and Folium Epimedii (FE), three of the extensively applied herbs among traditional Chinese medicines for gynecological disorders(1), including symptoms of Perimenopause.

Long-term treatment of RRF formula exhibited estrogenic properties, inhibited age-associated egeneration may be considered as an alternative/complementary medicine in relieving perimenopausal symptoms(1), according to the joint study lead by the Guangzhou University of Chinese Medicine.

Huang Qi or Bei Qi is also known as Astragalus root. The sweet herb has been used as diuretic agent and to lower blood pressure, increase blood pressure, lessens proteinuria, improve endurance, protect liver function, regulate blood sugar, etc.

In natural aging animal study, Radix Astragali used conjuction with Radix Angelicae Sinensis, and Folium Epimedii in formula RRF, expressed a a positive regulation on the estrogen imbalance and neurotransmitter disorder in restoring reproductive organ degeneration and skeleton deterioration in perimenopausal rats(2).

According to the Guangzhou University Town, RRF also enhanced estradiol (E(2) synthese while diminished the elevated serum FSH and LH levels, attenuated osteoporosis by elevating the BMD levels of total body and bone trabeculae degradation of which induced a capable of acting at multiple targets in the protection and treatment of perimenopausal disorders in midlife women(3).

Furthermore, RRF on study of immunological function, RRF also displayed a relatively wide margin of safety. Dr. Xie JH and colleagues at the joint study lead by the Guangzhou University of Chinese Medicine, Guangzhou said, "Long-term treatment of RRF exhibited estrogenic properties, and retarded certain age-associated degenerations" and "RRF might have the potential for further development as a safe and effective alternative/complementary to conventional medication in relieving perimenopausal symptoms."(4).

On Chinese medicinal plant Radix astragali(RA) alone in the study of 24 ovariectomized female Sprague-Dawley (SD) rats, oral application of RA significantly improved the immune functions of the ovariectomized female rats, but cannot induced the change the sex hormones levels as significantly as estrogen(5).

Dang Qui (Angelica sinensis) is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. Use conjunction with Radix Astragali and Folium Epimedii in formula RRF improved the aging degeneration of perimenopausal symptoms in animal study(2).

Folium Epimedii, deciduous or evergreen hardy perennials, native to Asia, and a few in the Mediterranean region has been used in Chinese medicine for induced sexual activity. When used together with Dang qui and Huang qi in formula RRF has shown effectively in enhanced the balancing of diminished hormones due to aging in reduced the expression of perimenopausal symptoms(3).

In take of phytoestrogen with function as weak estrogens, antioxidants, and anti-inflammatory agents(6) plant based lignans, a chemical compoud found in flax seed, may be effective in ameliorated symptoms of peri menopause, according to the joint study lead University of Zurich(7),

The combination of formula RRF and Flax Seed  smoothie may hold a key in further studies in production of an effective natural ingredients for reduced the symptoms displacement and treatment of perimenopause without inducing adverse effects.

Women who are in the perimenopause stage should drink as much as they can, depending to the digestive toleration.

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References

(1) Evaluation of safety of Modified-Danggui Buxue Tang in rodents: Immunological, toxicity and hormonal aspects by Xie JH1, Chen ZW2, Pan YW3, Luo DM3, Su ZR4, Chen HM1, Qin Z5, Huang SQ6, Lei G7.(PubMed)
(2) Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model by Su JY1, Xie QF2, Liu WJ1, Lai P1, Liu DD1, Tang LH1, Dong TT3, Su ZR4, Tsim KW3, Lai XP4, Li KY5.(PubMed)
(3) Effect of a derived herbal recipe from an ancient Chinese formula, Danggui Buxue Tang, on ovariectomized rats by Xie QF1, Xie JH, Dong TT, Su JY, Cai DK, Chen JP, Liu LF, Li YC, Lai XP, Tsim KW, Su ZR.(PubMed)
(4) Evaluation of safety of Modified-Danggui Buxue Tang in rodents: Immunological, toxicity and hormonal aspects by Xie JH1, Chen ZW2, Pan YW3, Luo DM3, Su ZR4, Chen HM1, Qin Z5, Huang SQ6, Lei G7.(PubMed)
(5) Effects of a Chinese medicinal plant Radix astragali on the ovariectomized female rats by Zheng Y1, Jin Y, Zhu HB, Xu ST, Xia YX, Huang Y.(PubMed)
(6) Urinary phytoestrogen levels and frailty in older American women of the National Health and Nutrition Examination Survey (NHANES) 1999-2002: a cross-sectional study by Eichholzer M1, Richard A, Walser-Domjan E, Linseisen J, Rohrmann S.(PubMed)
(7)  Urinary phytoestrogens and depression in perimenopausal US women: NHANES 2005-2008. by Richard A1, Rohrmann S2, Mohler-Kuo M3, Rodgers S4, Moffat R5, Güth U6, Eichholzer M2.(PubMed)

The Practical Smoothie to Prevent and Treat Constipation Back by Clinical Trials and Studies of Renowned Institutions

Kyle J. Norton(Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Constipation

Yield: 2 serving (about 8 ounce each)
1 1/2 prune juice
3/4 cup bran

1. Place tall ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Constipation with no adverse effects has exited may scientists community after many potential ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Constipation is a condition of difficulty in bowel movements. Plum the natural sources of fruit has been suggested and used by folk medicine and dietitian for treatment of chronic constipation.
Plum is a genus of Prunus, containing over 15 species, relatives of the peach, nectarine and almond, belongs to family Rosaceae and native to northern Asia, Europe, North America and Africa's northwest coast. Today it is cultivated all over the globe for commercial purpose as foods and alcoholic drink. Dr. Stacewicz-Sapuntzakis M1. professor at the University of Illinois at Chicago suggested, phenolic compounds in dried plums may process the effects in the gastrointestinal tract including prevention of constipation and possibly colon cancer(1).

In an 8-week, single-blind, randomised cross-over study, conducted by the University of Iowa Carver College of Medicine, in the comparison of dried plums (prunes) vs. psyllium for constipation, said," dried plums are safe, palatable and more effective than psyllium for the treatment of mild to moderate constipation, and should be considered as a first line therapy"(2).

In backing to the effectiveness of plume in reduced symptoms of constipation, Essex County Geriatric Center, New Jersey study showed that, a fiber-supplemented dietary included bran-supplemented hot cereal, a special fiber-prune juice supplement, and a fiber-rich liquid for tube-feedings alleviated the constipation in the elderly(3).

Bran, the hard outer layers of cereal grain may also used as laxative for treatment of constipation, according to a controlled blind parallel intervention trial among 30 frail inhabitants of a geriatric ward aged 57-100 years with laxative use(4).

According to the University of Vienna, adding oat-bran to common oral diet may reduce the use of laxatives by 59% and improve the well being and body weight of seniors of a long-term-care facility(5).

'Fiber 7', a natural powder fiber, including bran, adding to the dietary reduced the use of laxatives in 63 of the 92 patients (68.5%, 95% confidence interval 59-78%) with tolerated risk in a nursing home study(6)

The discover of combination ingredients of prune juice and fiber in reduced risk and treatment of constipation may serve as a cornerstone to contrive therapeutic experiment for further investigation.

Taking altogether, people who are at increased risk of  Constipation due to family history, gene mutation, aging,.. .....should drink at least one serving daily and people with chronic Constipation should drink the juices as much as they can, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

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References

(1) Dried plums and their products: composition and health effects--an updated review by Stacewicz-Sapuntzakis M1.(PubMed)

(2) Randomised clinical trial: dried plums (prunes) vs. psyllium for constipation.

Attaluri A1, Donahoe R, Valestin J, Brown K, Rao SS.(PubMed)

(3) Alleviation of constipation in the elderly by dietary fiber supplementation by Hull C, Greco RS, Brooks DL.(PubMed)

(4) Intervention with dietary fiber to treat constipation and reduce laxative use in residents of nursing homes by Sturtzel B1, Elmadfa I.(PubMed)

(5) Use of fiber instead of laxative treatment in a geriatric hospital to improve the wellbeing of seniors by Sturtzel B1, Mikulits C, Gisinger C, Elmadfa I.(PubMed)

(6) 'Fiber 7' supplement as an alternative to laxatives in a nursing home by Khaja M1, Thakur CS, Bharathan T, Baccash E, Goldenberg G.(PubMed)

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Prevention

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Restrictive lung diseases or restrictive ventilatory defects
Restrictive lung disease is a condition marked most obviously by a reduction in total lung capacity. A restrictive ventilatory defect may be caused by a pulmonary deficit, such as pulmonary fibrosis (abnormally stiff, non-compliant lungs), or by non-pulmonary deficits, including respiratory muscle weakness, paralysis, and deformity or rigidity of the chest wall(1).

 
                                                  The Prevention

1. Lose weight if you are Obese
Obesity is associated to the increased risk of Restrictive lung disease. According to the study to evaluate the effects of obesity on the pulmonary function of adult women, showed that the alterations evidenced in the components of the vital capacity (inspiratory reserve volume and expiratory reserve volume) suggest damage to the chest mechanics caused by obesity. These factors probably contributed to a reduction of the maximal voluntary ventilation(22).
2. Quit smoking
A similar trend was observed in the control group indicating that smoking had a deteriorating effect on spirometric tests. The results of the pulmonary function tests showed a predominantly restrictive type of pulmonary impairment (12.3%) followed by a mixed ventilatory defect (8.7%)(23).
3. Prevention of occupational causes of the diseases and second smoke
In the study to investigate symptomatology, lung function, and radiographic change over an average period of 8 to 9 yr, of Sixty-four subjects with asbestos-related diffuse pleural thickening attending the London Medical Boarding Centre for Respiratory Diseases, showed that Chest pain was a common symptom, occurring in over half of the subjects. Approximately one-third of the subjects had a history of pleurisy or pleural effusion. Full long function, available in all cases, showed a highly significant decrement (p < 0.001) compared with predicted values in all variables except gas transfer coefficient (Kco) at initial presentation, consistent with a restrictive ventilatory defect(24).
4. Traditional Mediterranean diet
Eating plenty of fruit, vegetables and fish keep lungs healthy. Those who follow a diet closest to this ” Mediterranean ” ideal are less likely as their peers with eating habits furthest from this pattern to develop chronic lung disease. A good amount of fresh vegetable juices are a good way to start healing, along with adding a variety of spices such as ginger, onions, and garlic. The emphasis should be on eating as healthy a diet as possible(25).
5. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(23) http://www.ncbi.nlm.nih.gov/pubmed/1915188 
(24) http://www.ncbi.nlm.nih.gov/pubmed/8542134 
(25) http://www.raysahelian.com/lungdisease.html

The Broccoli, and Flax seed smoothie for Ameliorated Menopausal Symptoms

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced symptoms and treatment of  Amenorrhea
Yield: 2 serving (about 8 ounce each)
1 1/4 cups broccoli
1/4 cup flax seed
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of vasomotor symptoms is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovaries functions in egg production because of less production of estrogen and progesterone,signalling the end of the reproductive phrase a woman's life. In menopause, menstruation has become irregular and slowly stop overtime, but in some women, menstrual flow comes to a sudden halt.
Isoflavones found in legume processed alleviating vasomotor episodes, attenuating bone loss, and stimulating vaginal epithelial maturation,. according to the joint study lead by The Chiang Mai University(1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).

Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve dpression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor ) are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).

The combination of Broccoli, and Flax seed smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of menopausal symptoms  without inducing adverse effects. Menopausal women  should drink as much as they can,  depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Short-Term Isoflavone Intervention in the Treatment of Severe Vasomotor Symptoms after Surgical Menopause: A Case Report and Literature Review by Teekachunhatean S1, Mattawanon N2, Khunamornpong S3.(PubMed)

(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)

(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)

(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)

(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)

(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)

(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Diagnosis

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Restrictive lung diseases or restrictive ventilatory defects
Restrictive lung disease is a condition marked most obviously by a reduction in total lung capacity. A restrictive ventilatory defect may be caused by a pulmonary deficit, such as pulmonary fibrosis (abnormally stiff, non-compliant lungs), or by non-pulmonary deficits, including respiratory muscle weakness, paralysis, and deformity or rigidity of the chest wall(1).

 
                                                  The Diagnosis 

If you are experience some of the above symptoms and if your doctor suspects that you have restrictive lung function, after recording your family history and completing the physical exam, the test which your doctor orders include
1. Chest CT scan and echocardiography
In the study to examine the frequency and spectrum of diseases associated with isolated reduction in the diffusing capacity of lung for carbon monoxide (D(Lco)) of the 38,095 patients who underwent PFTs during the study period, 179 (0.47%; 95% confidence interval [CI], 0.40%-0.54%) had isolated D(Lco) abnormalities. The 27 patients (15.1%; 95% CI, 10.2%-21.2%) who had also undergone chest CT and echocardiography within 1 month of PFTs form the study cohort reported herein. Their mean D(Lco) was 50% +/- 15% (95% CI, 45%-56%) with average normal pulse oxygen saturation at rest and mild hypoxemia with activity. Thirteen of the 27 patients (48%; 95% CI, 28.7%-68.1%) had underlying emphysema evident on CT. Eleven of these 13 patients had emphysema associated with a restrictive lung process. The 14 patients without emphysema had interstitial lung disease, pulmonary vascular disease, and other isolated findings(18).
2. Utility of cardiopulmonary exercise testing
Restrictive lung disease occurs commonly in patients with neuromuscular disease.Exercise testing is mandatory because pulmonary function tests at rest are not reliable for the diagnostic evaluation and functional characterisation of these patients. Cardiopulmonary exercise testing (CPET) with measurement of gas exchange is the favoured tool. It is an excellent method to investigate exercise dyspnea, describe altered physiological response to exercise and characterise the involved organ systems heart, lung and muscle(19).
3. FEV1/FVC ratio test
The aim of the test is to analyze the forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). In patients with restrictive lung disease, ratio is higher than 80% as the decline in FVC is more than that of FEV1. In the study use of clinical and spirometry findings in order to distinguish between the restrictive and nonspecific patterns of pulmonary function test results in patients with low FVC and a normal or elevated FEV1/FVC ratio, showed that the most common causes of a nonspecific pattern were obstructive disorders, congestive heart failure, obesity, bronchiolitis, interstitial diseases, and neuromuscular disorders. In patients given a working diagnosis of pulmonary fibrosis, pleural disease, or chest wall disease, the positive predictive value (PPV) for restriction was >or= 90%. In males, an FVC <or= 60% of predicted had a PPV for restriction of 98.8%. In females, the restrictive pattern was found in 84.4% of those with an FVC <or= 50% of predicted. A difference of >or= 0% between the FEV1% and the FVC% had a PPV for restriction of 89.5%. After performing logistic regression, we developed a point scale for predicting the restrictive pattern(20).
4. Spirometry
Spirometry measures the flow and volume of air entering and leaving the lungs. It is used to assess ventilatory function and differentiates between normality and diseases causing obstructive and possibly restrictive defects(21).
4. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(18) http://www.ncbi.nlm.nih.gov/pubmed/17285785
(19) http://www.ncbi.nlm.nih.gov/pubmed/19924618
(20) http://www.ncbi.nlm.nih.gov/pubmed/20835593
(21) http://www.ncbi.nlm.nih.gov/pubmed/21597532 

The Smoothie back by Clinical Trials and Studies of Respectable Institution of Olive, Broccoli and Mineral Water for Bipolar Disorder (Manic-Depressive)

Kyle J. Norton(Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of  Bipolar Disorder (Manic-Depressive)

Yield: 2 serving (about 8 ounce each)
1/4 cup olive
1/2 cups broccoli
3/4 cup grape
1 cup mineral water

1. Place tall ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of  Bipolar Disorder (Manic-Depressive) with no adverse effects has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Bipolar disorder (manic-depressive) is a condition of mood swing not driven by the events of life, but as a result of abnormal gene or certain brain circuits could underlie bipolar of that can impair daily functioning and normal functioning at work by alternating periods of elation and depression. Some researchers suggested that the oxidative stress induced cell damage may also influence as a pathophysiology of bipolar mood disorder patients(1).

Recent studies back by clinical trials and studies from respectable institutions, suggested that  omega-3 fatty acids(2) found in olive, alpha-lipoic acid found in broccoli(5) and mineral water(8) induced by cherry may be the next generation of therapeutic ingredient for reduced risk and treatment of Bipolar Disorder.

Olive is belongings to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil. According to the The University of Melbourne, in review of the literature data base suggested that Omega-3 fatty acids may play an important role for treatment of Bipolar Disorder(2).

Dr. Lin PY and Dr. Su KP., researchers at the Chang Gung University College of Medicine said,"our meta-analysis showed significant antidepressant efficacy of omega-3 PUFAs, it is still premature to validate this finding due to publication bias and heterogeneity"(3), in a meta-analytic review of double-blind, placebo-controlled trials.

In backing to the use of Omega 3 fatty acids for treatment of Bipolar Disorder, Dr. and colleagues at the suggested, strong evidence in epidemiological studies exhibited the substantial relationship between omega-3 PUFAs and depression plausibly in diverse populations(4).

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. It has large flower heads, usually green in color surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe. In Oxidative stress induced Bipolar Disorder, Alpha-lipoic acid (ALA) found abundantly in broccoli, exhibited a possible antimanic effect, through inhibited oxidative stress and neurotrophic factors involved in the pathophysiology of bipolar disorder (BD)(5).

In neuropsychiatric disorders, Alpha-lipoic acid (ALA) displays a possible therapeutic neuroprotective effect against mitochondrial dysfunction when used conjunction with acetyl-L-carnitine (ALCAR), according to the Biological Psychiatry Laboratory, McLean Hospital(6).

In support of the effectiveness of (ALA) against Bipolar Disorder

Dr. Nierenberg AA and researchers at the Massachusetts General Hospital, Boston suggested in the treatment of bipolar patients with frequently relapse within 12 months of their previous mood episode, inhibition of mitochondrial dysfunction and potential MMs by alpha-lipoic acid (ALA), may be the best in reduced the pathophysiology of bipolar disorder(7).

Mineral water, a major source of lithium have found to be effective in preventing and treating Bipolar disorder(8).

Dr. Ketter TA, and colleagues at the Stanford University School of Medicine, in the comparison of the efficacy of quetiapine and lithium in acute mania, suggested the possibly greater efficacy for quetiapine compared with lithium in acute bipolar depression and in prevention of recurrent (particularly depressive) episodes(9).

In a single-blind, randomised controlled trial on a cohort of 61 participants following first episode mania, early treatment with of lithium treatment may benefit the trajectory of cognition, such as verbal fluency in young people with bipolar disorder, according to the joint study lead by the Centre for Youth Mental Health, University of Melbourne(10).

The effectiveness of ingredients of olive, broccoli and mineral water should mimic the similar efficiency of their phytochemicals. It is hard to convince people that a enjoyable and delicious smoothie loved by everyone in the hot Summer day may consist the therapeutic values for reduced risk and treatment of some acute and chronic illness even they are back the clinical trials and studies by respectable institutions.
People who are at increased risk of  Bipolar Disorder due to family history, gene mutation, psychological problem.. .....should drink at least one serving daily and people with  Bipolar Disorder should drink the juices as much as they can, depending to digestive toleration.
Change of life style and diet pattern are also recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(1) Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic andbipolar mood disorder patients by Ranjekar PK1, Hinge A, Hegde MV, Ghate M, Kale A, Sitasawad S, Wagh UV, Debsikdar VB, Mahadik SP.(PubMed)

(2) Omega-3 for bipolar disorder: meta-analyses of use in mania and bipolar depression by Sarris J1, Mischoulon D, Schweitzer I.(PubMed)

(3) A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids by Lin PY1, Su KP.(PubMed)

(4) Omega-3 polyunsaturated fatty acids and depression: a review of the evidence and a methodological critique by Sontrop J1, Campbell MK.(PubMed)

(5) Effects of alpha-lipoic acid in an animal model of mania induced by D-amphetamine by Macêdo DS1, Medeiros CD, Cordeiro RC, Sousa FC, Santos JV, Morais TA, Hyphantis TN, McIntyre RS, Quevedo J, Carvalho AF.(PubMed)

(6) A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression by Brennan BP1, Jensen JE, Hudson JI, Coit CE, Beaulieu A, Pope HG Jr, Renshaw PF, Cohen BM.(PubMed)

(7) Mitochondrial modulators for bipolar disorder: a pathophysiologically informed paradigm for new drug development by Nierenberg AA1, Kansky C, Brennan BP, Shelton RC, Perlis R, Iosifescu DV.(PubMed)

(8) Lithium for maintenance treatment of mood disorders by Burgess S1, Geddes J, Hawton K, Townsend E, Jamison K, Goodwin G.(PubMed)

(9) Treatment of bipolar disorder: Review of evidence regarding quetiapine and lithium.

Ketter TA1, Miller S2, Dell'Osso B3, Wang PW2.(PubMed)

(10) A single-blind, randomised controlled trial on the effects of lithium and quetiapine monotherapy on the trajectory of cognitive functioning in first episode mania: A 12-month follow-up study by Daglas R1, Cotton SM2, Allott K2, Yücel M3, Macneil CA4, Hasty MK4, Murphy B5, Pantelis C6, Hallam KT7, Henry LP8, Conus P9, Ratheesh A10, Kader L4,Wong MT11, McGorry PD10, Berk M12.(PubMed)

Most Common Diseases of elder: Restrictive lung diseases (Respiratory Disease): The Risk Factors and Diseases Associated to

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Restrictive lung diseases or restrictive ventilatory defects
Restrictive lung disease is a condition marked most obviously by a reduction in total lung capacity. A restrictive ventilatory defect may be caused by a pulmonary deficit, such as pulmonary fibrosis (abnormally stiff, non-compliant lungs), or by non-pulmonary deficits, including respiratory muscle weakness, paralysis, and deformity or rigidity of the chest wall(1).

 
                                      The Risk Factors and Diseases Associated to

Risk factors
1. Second hand smoke and genetic influence
Cigarette smoke not only causes Respiratory Disease, including Restrictive lung disease but also can influence early immune function as a potential to interact with other genetic factors and environmental risk factors to influence disease propensity(10).
2. Obesity
Obesity, particularly severe central obesity, affects respiratory physiology both at rest and during exercise as a result of ventilatory defect due to reductions in expiratory reserve volume, functional residual capacity, respiratory system compliance and impaired respiratory system. In the study by National Taiwan University Hospital, showed that obesity may also impair upper airway mechanical function and neuromuscular strength, and increase oxygen consumption, which in turn, increase the work of breathing and impair ventilatory drive. The combination of ventilatory impairment, excess CO(2) production and reduced ventilatory drive predisposes obese individuals to obesity hypoventilation syndrome(11).
3. Race
African Americans are at higher risk than white race in development of Restrictive lung disease.
4. Age
As the disease is a result of progression over prolonged period of time, most patients with restrictive lung disease are older than 50 years.
5. Etc.

Diseases associated with restrictive lung diseases
1. Heart diseases
In the study to explore the association of COPD and restrictive lung function impairment, respectively, with heart diseases in the general population in a cross-sectional study of 642 randomly selected 22- to 72-year-old subjects in northern Swede, found that there is a strong association between COPD and cardiovascular diseases and indicates a strong association between restrictive lung function and heart diseases. Both obstructive and restrictive lung function impairments were common among subjects with heart diseases and vice versa(12).
2. Ulcerative colitis
There is an association between ulcerative colitis and lung disease in which patients have chronic cough and show hyperplastic and inflammatory changes in their bronchial mucosa, according to the study by
Guy’s Hospital and Brook General Hospital(13).
3. Syringomyelia and syringobulbia
There is a report of three patients with syringomyelia and syringobulbia who developed severe respiratory complications. In neurological examination showed evidence of IXth and Xth cranial nerve involvement with dysphagia and dysphonia, but there were no complaints of serious sleep difficulties. Two patients died during sleep and the other was resuscitated during a nap. All patients showed moderate restrictive ventilatory defects with reduced maximal buccal pressures and one also showed a low ventilatory response to CO2 rebreathing(14).
4. Sarcoidosis
In the study to assess various lung function indices, including C(L,s) and D(L,CO), as markers of functional abnormality in sarcoidosis patients from 830 consecutive patients referred for lung function tests with a diagnosis of sarcoidosis (223 in stage I, 486 in stage II and 121 in stage III), found that
Normal total lung capacity was found in 772 (93%) patients. Of these cases, 24.5% had a low C(L,s) and 21.5% had a low D(L,CO). At least one abnormality was observed in 39.3% of these patients, whereas, in restrictive patients, this figure was 88%. Airway obstruction was present in 11.7% of cases(15).
5. Neuromuscular disease
The earliest sign of respiratory compromise in the patient with neuromuscular disease is nocturnal hypoventilation, which progresses over time to include daytime hypoventilation and eventually the need for full-time mechanical ventilation(16).
6. Other diseases
According to the study by Department of Public Health and Clinical Medicine, Umeå University, in restrictive lung function the prevalence of chronic rhinitis, cardiovascular disease, hyperlipemia and diabetes was higher compared to in Nlf (41.0% vs 32.3%, p = 0.017, 59.0% vs 41.0%, p<0.001, 29.2% vs.12.9%, p = 0.033, 20.9% vs 8.6%, p <0.001). In COPD and heart disease, 62.5% had chronic rhinitis and/or GERD, while in Nlf the corresponding proportion was 42.5%(17).
7. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1)http://oac.med.jhmi.edu/res_phys/Encyclopedia/RestrictVentDefect/RestrictVentDefect.HTML
(11) http://www.ncbi.nlm.nih.gov/pubmed/22212441 
(12) http://www.ncbi.nlm.nih.gov/pubmed/23127573 
(13) http://thorax.bmj.com/content/35/8/581.full.pdf
(14) http://www.ncbi.nlm.nih.gov/pubmed/1640236 
(15) http://www.ncbi.nlm.nih.gov/pubmed/20378598 
(16) http://www.ncbi.nlm.nih.gov/pubmed/23137740 
(17) http://www.ncbi.nlm.nih.gov/pubmed/22149402