Tuesday, March 15, 2016

The Workable Green Tea, Orange and Turmeric for Prevention and Treatment of Cirrhosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Cirrhosis
Yield: 2 servings (about 8 ounces each)
1 1/2 cups orange
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Cirrhosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Cirrhosis is defined as a condition of irreversible scarring liver as a result of liver tissue by fibrosis due to final phase of chronic liver diseases of that can lead to poor function of the liver and liver failure.
Recent studies back by well known institutions proposed, Green Tea, Vitamin E, and  Resveratrol and Silymarin isolated from Tomato, Sweet Potato and Peanut respectively may be the next generation of natural ingredients for prevention and treatment of Cirrhosis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Fudan University, intake of green tea extracts (GTE) can protect against CCl(4)-induced liver damage and cirrhosis in animal model(1).
Dr.Yin X and colleagues at the joint study lead by the Zhujiang Hospital of Southern Medical University, regular intake of green tea intake is associated to reduce risk of liver disease, including liver cirrhosis(2).
In the study of the effect of Green Tea Extract (GTE) encapsulated into Chitosan Nanoparticles (CS-NPs), researchers showed that the combination are effective in removing all the extracellular collagen caused by CCl4 in the hepatic fibrosis rat liver(3).

Hesperetin, found abundantly in Citrus fruits, including orange also expressed hepatoprotective effect
against liver fibrosis through targeting the Wnt/β-catenin signaling pathway in diseases contribution(4). According to the Renmin Hospital of Wuhan University, orange flavonoid hesperetin also protected against cardiac remodelling induced by pressure overload via inhibiting cardiac hypertrophy, fibrosis, oxidative stress and myocytes apoptosis(5).

Curcumin, a spice derived from Tuermic not only attenuated hepatic damage in several animal models of liver injury but also inhibited the development liver cirrhosis through its anti-inflammatory activities(6).

According to the Sección Externa de Farmacología, Cinvestav-IPN, Curcumin was effective in preventing and reversing cirrhosis, probably through reducing TGF-beta expression in regulation of proliferation, cellular differentiation, and other functions in most cells(7).
Furthermore, curcumin also exerted liver protective effect against liver damage induced chronic liver diseases, including cirrhosis(8).

Taking altogether, the combination of Orange, Turmeric and Green Tea may process the activities in reduced risk and treatment of patient with Cirrhosis

People who are at increased risk of Cirrhosis due to family history, .... should drink 1 serving daily and people with Cirrhosis should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

References
(1) [Green tea extracts protected against carbon tetrachloride-induced chronic liver damage and cirrhosis].[Article in Chinese] by Xiao J1, Lu R, Shen X, Wu M.(PubMed)
(2) The effect of green tea intake on risk of liver disease: a meta analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(3) Effect of Green Tea Extract Encapsulated Into Chitosan Nanoparticles on Hepatic Fibrosis Collagen Fibers Assessed by Atomic Force Microscopy in Rat Hepatic Fibrosis Model by Safer AM, Hanafy NA, Bharali DJ, Cui H, Mousa SA.(PubMed)
(4) Hesperetin derivative-7 inhibits PDGF-BB-induced hepatic stellate cell activation and proliferation by targeting Wnt/β-catenin pathway by Lin X1, Kong LN1, Huang C1, Ma TT1, Meng XM1, He Y1, Wang QQ1, Li J2.(PubMed)
(5) Hesperetin protects against cardiac remodelling induced by pressure overload in mice. by Deng W1, Jiang D, Fang Y, Zhou H, Cheng Z, Lin Y, Zhang R, Zhang J, Pu P, Liu Y, Bian Z, Tang Q.(PubMed)
(6) Prevention of liver cirrhosis in rats by curcumin. by Bruck R1, Ashkenazi M, Weiss S, Goldiner I, Shapiro H, Aeed H, Genina O, Helpern Z, Pines M.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Diagnosis

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Diagnosis

If you are experience some symptoms above, after recording the family history and the complete physical examination, the tests which you doctor orders include
1. X ray
In most case, pneumothorax can be detected by X ray as the image of pneumothorax as thoracic cavity is partly filled with air occupying the pleural space. If the X-ray does not show a pneumothorax but your doctoe strong suspicion of one, lateral X-rays (with beams projecting from the side) may be performed. There is a report of Two medicolegal cases involvin chest X-ray with left-and-right side confusion due to lack of radio-opaque side markers(43).
2. Ultrasound
Ultrasound (US) is a sensitive diagnostic tool for detecting pneumothorax (PTX). According to the study by Norwegian Air Ambulance Foundation, in the study to define the distribution of air using the reference imaging standard computed tomography (CT), to see if pleural insufflation of air into a live anaesthetized pig truly imitates a PTX in an injured patient, indicated that the distribution of the intrathoracic air to be similar between a porcine model and that to be expected in human trauma patients, all having predominantly anterior PTX topographies. In a training facility, the model is easy to set up and can be scanned by the participants multiple times. To acquire the necessary skills to perform thoracic US examinations for PTX, the porcine models could be useful(44).
3. CT scan
There is a reprot of 3 cases which serve for better understanding of the entity of occult pneumothorax. The first case is an example of a true occult pneumothorax where an initial AP chest X-ray revealed no evidence of pneumothorax and a CT chest immediately performed revealed evidence of pneumothorax. The second case represents an example of a missed rather than a truly occult pneumothorax where the initial chest radiograph revealed clues suggesting the presence of pneumothorax which were missed by the reading radiologist. The third case emphasizes the fact that “occult pneumothorax is predictable(45).
Other study in the aetiological diagnosis and subsequent management of patients with primary spontaneous pneumothorax, found that in 75% of these cases, CT revealed underlying lung pathology as a cause for primary spontaneous pneumothorax(46).

Sources
(43) http://www.ncbi.nlm.nih.gov/pubmed/11960251
(44) http://www.ncbi.nlm.nih.gov/pubmed/22594363
(45) http://www.ncbi.nlm.nih.gov/pubmed/21951659
(46) http://www.ncbi.nlm.nih.gov/pubmed/12866634

The Tasty Smoothie of Sweet Potato, Carrot and Low Fat Milk for Prevention and Treatment of Hepatitis B

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Hepatitis B
Yield: 2 servings (about 8 ounces each)
1 1/4 cups sweet potato
1/4 cup carrot
1 cup of low fat milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
The finding of a natural source for treatment of hepatitis C has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hepatitis B is a liver inflammatory disease caused by the hepatitis B virus (HBV). Some people infected by the virus without showing any symptoms and become the viral carrier. Others may experience chronic infection induced liver scaring, cirrhosis,,....

Recent studies back by well known institutions proposed, Vitamin E Broccoli, Artichoke and and Brazil nut may be the next generation of natural ingredients for prevention and treatment of hepatitis B.

Vitamin E, a fat soluble vitamin found abundantly in sweet potato may be an potential natural ingredient for prevention and treatment of Hepatitis B as serum of vitamin E is lower with patients with acute or chronic viral hepatitis(1). According to results of a randomized controlled pilot trial, vitamin E supplementation might be effective in the treatment of chronic hepatitis B, through increased the host immune response against the invasion of the virus(2).Dr. Fan XP and professors at the Qilu Hospital of Shandong University, intake of vitamin E supplement attenuated the progression of liver inflammation and promoted HBeAg seroconversion(4) in the patients with chronic hepatitis B(3).
Lower serum of vitamin D concentration found abundantly through sun exposure and intake of milk is also found to associate to patients with hepatitis B(5). According to the joint study led by the Sichuan University, increased levels of vitamin D in chronic hepatitis B (CHB) may be necessary for long term treatment of patients with hepatitis B.(6).
Vitamin A, a fat soluble vitamin found abundantly in tomato and carrot may also be used for prevention and treatment of Hepatitis B(7).
According to the Centers for Disease Control and Prevention in Laiwu City, "vitamin A in serum maybe has certain relationship with maintaining effective protection level of anti - HBs antibody and measles IgG antibody"(7). In support to the effectiveness of vitamin A, the ClinicalTrials.gov: NCT01583972. study suggested, Connecting different aspects of immunological data in early infancy, including maintaining the right levels of vitamin A will help elucidate immune competence for protecting infection(8).

The effectiveness of Sweet Potato, Carrot and Low Fat Milk  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk treatment of Hepatitis B with little or no adverse effects.

People who are at high risk of Hepatitis B due to weaken immune system,.environment factor.... should drink at least one serving daily and people with Hepatitis B should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

References
(1) Diminished plasma levels of vitamin E in patients with severe viral hepatitis by von Herbay A1, Stahl W, Niederau C, von Laar J, Strohmeyer G, Sies H.(PubMed)
(2) Vitamin E as treatment for chronic hepatitis B: results of a randomized controlled pilot trial by Andreone P1, Fiorino S, Cursaro C, Gramenzi A, Margotti M, Di Giammarino L, Biselli M, Miniero R, Gasbarrini G, Bernardi M.(PubMed)
(3) [Study on the relationship of serum vitamin E and liver pathological features in the patients with chronic hepatitis B].[Article in Chinese] by Fan XP1, Wang K, Wang GW, Fan YC.(PubMed)
(4) Vitamin E treatment for children with chronic hepatitis B: a randomized placebo controlled trial by Gerner P1, Posselt HG, Krahl A, Ballauff A, Innerhofer A, Binder C, Wenzl TG, Zense M, Hector A, Dockter G, Adam R, Neubert J, Classen M, van Gemmern R,Wirth S.(PubMed)
(5) Low vitamin D serum concentration is associated with high levels of hepatitis B virus replication in chronically infected patients by Farnik H1, Bojunga J, Berger A, Allwinn R, Waidmann O, Kronenberger B, Keppler OT, Zeuzem S, Sarrazin C, Lange CM.(PubMed)
(6) Sustained suppression of viral replication in improving vitamin D serum concentrations in patients with chronichepatitis B by Chen EQ1,2, Bai L1,2, Zhou TY1,2, Fe M1,2, Zhang DM1,2, Tang H1,2.(PubMed)
(7) The research for the relationship between nutritional status of vitamin A in infant's body and immunization effect of hepatitis B and measles vaccine by Ni S1, Wei L1, Liu Y1, Tang J1.(PubMed)
(8) The effect of newborn vitamin A supplementation on infant immune functions: trial design, interventions, and baseline data by Ahmad SM1, Raqib R2, Qadri F3, Stephensen CB4.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Misdiagnosis

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Misdiagnosis

According to the study by Medical Intensive Care Unit, Fitzsimons Army Medical Center, in the evaluation to identify risk factors predisposing to the misdiagnosis of pneumothorax in the ICU, showed that Nineteen (67.9%) patients with pneumothorax were diagnosed correctly on initial presentation of their pneumothorax. The remaining nine (32.1%) patients’ pneumothoraces were misdiagnosed at initial presentation. Certain medical ICU patients appear to be at higher risk for the initial misdiagnosis of pneumothorax. Familiarity with factors predisposing to this problem should allow for a higher index of suspicion for the diagnosis of pneumothorax in critically ill patients and possibly improve the early detection of pneumothorax(42).
1. Anaphylactic reaction of ruptured pulmonary hydatid cyst
There is a report of a 22-year-old male came to our emergency department in shock with symptoms of shortness of breath and altered mental status from the previous day. Radiograph showed a thin-walled circular translucent area in the right upper lung field, which was misdiagnosed as pneumothorax, and an intercostal chest tube was inserted. Anaphylactic reaction due to rupture of a hydatid cyst is rare, but hydatid disease should be suspected in patients from areas where Echinococcus is endemic, according to the Aligarh Muslim University(37).
2. MacLeod syndrome (Swyer-James syndrome)
There is a report of a 26-year-old man who had had a first left pneumothorax at the age of 21. He smokes tobacco. When he was 1-year-old he had experienced repeated episodes of acute bronchiolitis. At age 26, he suffered from a second left pneumothorax which was wrongly diagnosed as a recurrent drain-resistant pneumothorax. According to the study by Service de chirurgie infantile, hôpital Mère-Enfant, MacLeod syndrome is rare. It can be associated with pneumothorax which can be a source of misdiagnosis and error in the management of these patients(38).
3. Bronchogenic cysts
There is a report of a giant bronchogenic cyst in a 19-year-old woman presenting with pain and shortness of breath was mistaken for tension pneumothorax and initially treated with tube thoracostomy, according to Bursa Yuksek Ihtisas Hospital, Bursa(39).
4. Laparoscopic Nissen fundoplication
There is a report of a 13-year-old boy who, after exercise, had respiratory distress and left upper quadrant abdominal pain. Initially, a mistaken diagnosis of pneumothorax. And a nasogastric tube was then visualized on chest x-ray in the left hemithorax. He underwent a laparotomy and had herniation of spleen, stomach, and large and small bowel in the left pleural space passing through a traumatic defect in the hemidiaphragm but later felt to be conrtibuted by laparoscopic Nissen fundoplication 3 years prior(40).
5. Congenital diaphragmatic hernia
There is a report of two cases in which the initial diagnosis was tension pneumothorax and chest drains were inserted, but in both cases, the diagnosis turned out to be congenital diaphragmatic hernia(41).

Sources
(37) http://www.ncbi.nlm.nih.gov/pubmed/21333077
(38) http://www.ncbi.nlm.nih.gov/pubmed/23200584
(39) http://www.ncbi.nlm.nih.gov/pubmed/20947603
(40) http://www.ncbi.nlm.nih.gov/pubmed/15793743
(41) http://www.ncbi.nlm.nih.gov/pubmed/9292904
(42) http://www.ncbi.nlm.nih.gov/pubmed/2055079

Monday, March 14, 2016

The Fabulous Green Tea and Orange Smoothie for Prevention and Treatment of Gallstones

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Gallstones
Yield: 2 servings (about 8 ounces each)
1 1/2 cups orange
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Gallstones has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Gallstones are crystalline concretion, hard, pebble-like deposits formed in side the gallbladder, resulting in obstruction of the biliary tree which can lead to infection of the bile ducts with symptoms of constant pain, biliary coli, etc.

Recent studies back by well known institutions proposed, the combination of Green Tea,and Orange may be the next generation of natural ingredients for prevention and treatment of Gallstones.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Shanghai Cancer Institute, tea consumption was inversely associated with risk of ...... gallstone disease among females(1).
In the study to identify dietary factors and lifestyle patterns among southern Indian patients with GS disease, suggested that less frequent green tea and coffee intake are associated to higher risk of forming of gallstones(2).
Vitamin C found abundantly in orange is found to modify bile cholesterol crystallization process, the first step in cholesterol gallstone formation(3). Dr. Gustafsson U and colleagues also suggested that the influence the conditions for cholesterol gallstone formation in humans(4).
In an observational, population-based study of 2129 subjects aged 18-65 years randomly selected from the general population in southern Germany, proposed regular vitamin C supplementation might exert a protective effect on the development of gallstones(5).

Taking altogether, the combination of Green Tea and Orange may process the activities in prevention and treatment of Gallstones

People who are at higher risk of  Gallstones forming due to family history, dietary pattern, .... should drink 1 serving daily and people with Gallstones should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended


References
(1) [Tea consumption and risk of biliary tract cancers and gallstone disease: a population-based case-control study in Shanghai, China].[Article in Chinese] by Zhang XH1, Gao YT, Rashid A, Deng J, Liu EJ, Wu K, Sun L, Cheng JR, Gridley G, Hsing AW.(PubMed)
(2) Risk profile for gallstone disease in southern Indian population: is there anything new? by Chandran AP1, Sivarajan R, Srinivasan V, Srinivas M, Jayanthi V.(PubMed)
(3) [Effects of vitamin C administration on cholesterol gallstone formation].[Article in Spanish] by del Pozo R, Muñoz M, Dumas A, Tapia C, Muñoz K, Fuentes F, Maldonado M, Jüngst D.(PubMed)
(4) The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterolgallstones: prolongation of the nucleation time By Gustafsson U1, Wang FH, Axelson M, Kallner A, Sahlin S, Einarsson K.(PubMed)
(5) Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population by Walcher T1, Haenle MM, Kron M, Hay B, Mason RA, Walcher D, Steinbach G, Kern P, Piechotowski I, Adler G, Boehm BO, Koenig W, Kratzer W; EMIL study group(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pneumothorax - The Diseases associated to Pneumothorax

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pneumothorax

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pneumothorax is a condition of collection of air within the pleural cavity, from either the outside or from the lung of which affect the lung breathing.

The Diseases associated to Pneumothorax

1. Intraventricular hemorrhage
Intraventricular hemorrhage (IVH) is one of the major causes of the cerebral palsy and mental retardation. Prevention and early management of these neurologic developmental problems will require determining the perinatal risk factors associated with this clinical entity. Pneumothorax increase the risk of IVH, and cause of pneumothorax has an important effect in severity of IVH(30).
2. Swyer-James Syndrome
There is a report of a 21-year-old man with a history of bronchial asthma during childhood presented with left recurrent pneumothorax(31).
3. Lymphangioleiomyomatosis (LAM)
Lymphangioleiomyomatosis (LAM) is a rare lung disease of unknown etiology, described since 1918 associated with tuberous sclerosis complex (TSC-LAM) and are reported sporadically (S-LAM). There is a report of 2 patients with Lymphangioleiomyomatosis (LAM) in an admission of the Instituto Mexicano del Seguro Social, Distrito Federal, México, both present with spontaneous pneumothorax(32).
4. Osteosarcoma
Spontaneous pneumothorax is a rare manifestation of primary lung cancer or metastasis. It is estimated that < 1% of all cases of spontaneous pneumothorax are tumor-associated and metastatic osteogenic or soft-tissue sarcomas are associated most commonly with pneumothorax especially in the setting of cytotoxic chemotherapy or radiotherapy. There is a report of three pediatric cases with osteosarcoma that developed spontaneous pneumothorax during chemotherapy with a review of the literature. Two of them had lung metastasis at the time of the detection of pneumothorax and the remaining patient was found to have a bronchopleural fistula(33).
5. Tumours of the lung
Tumours of the lung, primary or secondary, may occasionally be complicated by a pneumothorax, and on rare occasions this may be the presenting feature. Metastatic tumours associated with pneumothorax arise usually from bone or soft tissue sarcomas and hence are more common in the young(34).
6. Interstitial pneumonia
Secondary pneumothorax occurring in interstitial lung disease cases is a refractory and life-threatening condition, because of compromised lung function. There is a report of a 70-year-old woman with interstitial pneumonia was referred to our hospital after treatment failure for pneumothorax associated with empyema(35).
7. Lung infection caused by Mycobacterium marinum
Mycobacterium marinum is a waterborne mycobacterium that commonly infects fish and amphibians worldwide, but transmission to humans can occasionally occur, typically as a granulomatous skin infection following minor hand trauma. There is a report of a case in August 2008, an 81-year-old man was admitted to a hospital for detailed examination of weight loss and an abnormal shadow on chest imaging found to be M. marinum-associated pneumonia and pneumothorax(36).
8. Etc.

Sources
(30) http://www.ncbi.nlm.nih.gov/pubmed/22930379
(31) http://www.ncbi.nlm.nih.gov/pubmed/23411839
(32) http://www.ncbi.nlm.nih.gov/pubmed/23182263
(33) http://www.ncbi.nlm.nih.gov/pubmed/23175928
(34) http://www.ncbi.nlm.nih.gov/pubmed/1064499
(35) http://www.ncbi.nlm.nih.gov/pubmed/23054619
(36) http://www.ncbi.nlm.nih.gov/pubmed/22606882

The Best Smoothie of Grape, Turmeric and Green Tea for Prevention and Treatment of Hemochromatosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Hemochromatosis

Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 tsp Turmeric powder
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Hemochromatosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hemochromatosis is a hereditary disorder with iron salts deposited in the tissues, leaded to liver damage, diabetes mellitus, and bronze discoloration of the skin.

Recent studies back by well known institutions proposed, Grape, Turmeric and  Green Tea may be the next generation of natural ingredients for prevention and treatment of Gilbert’s Syndrome. Dr. Isa HM and Dr. Mohamed AM. said, "Neonatal hemochromatosis is a rare liver disease of newborns with a spectrum of clinical severity......The use of antioxidant therapy helps to improve the outcome"(3).

Resveratrol, phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape inhibited abnormal iron metabolism and directly protected the liver from iron-mediated injury through its pleotropic antioxidant properties(1).
According to joint study lead by the University of Alberta, resveratrol ameliorated the burden from iron-overload cardiomyopathy at early and chronic stages of iron-overload(2).

Silybin, an antioxidant found abundantly in Turmeric, a yellow powder and used as a spice in curry dishes may be beneficiary for patient with Hemochromatosis. According to King's College London, silybin reduced iron absorption in patients with hereditary haemochromatosis through reduction in the postprandial increase in serum iron (AUC±s.e.)(4).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the der Johann Wolfgang Goethe-Universität, regular tea drinking with meals reduces the frequency of phlebotomies required in the management of patients with haemochromatosis. due to its inhibition of intestinal absorption of non-haem iron(5).

Dr. Borch-Iohnsen B, in the study of Primary haemochromatosis diet said," (regular) tea or coffee with meals will reduce iron absorption"(6).

Taking altogether, the combination of Grape, Turmeric and Green Tea may process the activities in reduced risk and treatment of patient with Hemochromatosis.

People with gene mutation of  Hemochromatosis due to family history, genetic mutation, .... should drink 1 serving daily and people with Hemochromatosis induced live disease should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

References
(1) Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload by Das SK1, DesAulniers J1, Dyck JR2, Kassiri Z3, Oudit GY1,3.(PubMed)
(2) Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy by Das SK1,2, Wang W2,3, Zhabyeyev P1,2, Basu R1,2, McLean B2,3, Fan D2,3, Parajuli N1,2, DesAulniers J1,2, Patel VB1,2, Hajjar RJ4, Dyck JR5, Kassiri Z2,3,Oudit GY1,2.(PubMed)
(3) Neonatal hemochromatosis. Case series from Bahrain by Isa HM1, Mohamed AM.(PubMed)
(4) The iron-chelating potential of silybin in patients with hereditary haemochromatosis. by Hutchinson C1, Bomford A, Geissler CA.(PubMed)
(5) Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis by Kaltwasser JP1, Werner E, Schalk K, Hansen C, Gottschalk R, Seidl C.(PubMed)
(6) [Primary hemochromatosis and dietary iron].[Article in Norwegian] by Borch-Iohnsen B1.(PubMed)