Friday, March 25, 2016

The Smoothie of Cooked Tomato, Peanut and Olive for Prevention and Treatment in Autosomal dominant polycystic kidney disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  polycystic kidney disease (Renal cystic disease) 
Yield: 2 servings (about 8 ounces each)
3/4 cup cooked tomato
1/2 cup peanut
1/4 cup olive
1 cup rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
Autosomal dominant polycystic kidney disease, one of the most common forms of polycystic kidney disease is inherited diseases effecting approximately 400,000 people in the United States.

The finding of a natural source for treatment of Polycystic kidney disease (Renal cystic disease) in autosomal dominant polycystic kidney disease, has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Polycystic Kidney Disease in a utosomal dominant polycystic kidney disease,is an inherited diseases with fluid-filled cysts developed on the kidney. According to the University of Kansas Medical Center, the disease is associated to risk factors of aging, in older persons with multiple cysts probably induced by potassium deficiency, congenital disorders, metabolic diseases, and toxic renal injury(1).

Recent studies back by well known institutions proposed, Cooked Tomato, Peanut and Olive may be the next generation of natural ingredients for reduced complications and treatment of Polycystic kidney disease.

Vitamin B3 , also known as niacin, is a water-soluble vitamin.Vitamin B3 found abundantly in peanut may benefit patient with polycystic kidney disease(2). According to C.J. Janovy, administration of Vitamin B3 to a neonate, toddler or adolescent will effectively prevent or delay cyst formation and can be used for a lifetime(2).
Dr. Al Adlouni A and Dr. Hertig A. Said, "Vitamin B3 exhibited anti  autosomal dominant effect  involed the develop of polycystic kidney disease"(3).

Omaga 3 fatty acids found abundantly in flax seed also attenuated the progression of polycystic kidney disease, through alternation of multiple steps in PKD pathogenesis(4). According to the University of Guelph, mice fed with an n-3 fatty acid-enriched diet (MaxEPA) for 60 days, showed a marked decrease in the proportion of kidney area occupied by cysts in male but not in female rat(5).
Dr. Yamaguchi T and colleagues in the study led by the University of Manitoba, said,"Dietary flax oil may therefore reduce disease progression via mitigation of oxylipin abnormalities"(6) in patients with renal diseases.

Retinoic acids all-trans retinoic acid (AT-RA) and 9-cis retinoic acid (9C-RA) with function as of vitamin A suppressed the activation of the poly cystic kidney disease-1 (PKD1) promoter in's attenuated the diseases' progression(7). 
 Dr.Yamane A and professors at the Gunma University Graduate School of Medicine, said," A 63-year-old APL patient, complicated by Child-Pugh class A liver cirrhosis and polycystic kidney (creatinine 3.2 mg/dL), was successfully treated with 45 mg/m(2)/day of all-trans retinoic acid (ATRA)"(8).

The effectiveness of  Cooked Tomato, Peanut and Olive may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of polycystic kidney disease (Renal cystic disease) with little or no adverse effects.

People who are at high risk of polycystic kidney disease (Renal cystic disease) due to aging, weaken reno function... should drink at least one serving daily and women with polycystic kidney disease (Renal cystic disease) should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.



Refeneces
(1) Polycystic kidney disease: etiology, pathogenesis, and treatment by Martinez JR1, Grantham JJ.(PubMed)
(2) Vitamin B3 holds promise for treating polycystic kidney disease, research suggests, June 17, 2013
By C.J. Janovy
(3) [Vitamin B3 to prevent autosomal dominant polycystic kidney disease].[Article in French] by Al Adlouni A1, Hertig A2.(PubMed)
(4) Evidence for a role of proteins, lipids, and phytochemicals in the prevention of polycystic kidney disease progression and severity by Maditz KH1, Gigliotti JC, Tou JC.(PubMed)
(5) Effects of dietary supplementation with n-3 fatty acids on kidney morphology and the fatty acid composition of phospholipids and triglycerides from mice with polycystic kidney disease by Yamaguchi T1, Valli VE, Philbrick D, Holub B, Yoshida K, Takahashi H.(PubMed)
(6) Dietary flax oil rich in α-linolenic acid reduces renal disease and oxylipin abnormalities, including formation of docosahexaenoic acid derived oxylipins in the CD1-pcy/pcy mouse model of nephronophthisis by Yamaguchi T1, Devassy JG1, Gabbs M2, Ravandi A3, Nagao S4, Aukema HM5.(PubMed)
(7) Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter by Islam MR1, Puri S, Rodova M, Magenheimer BS, Maser RL, Calvet JP.(PubMed)
(8) Successful treatment by all-trans retinoic acid in a patient with acute promyelocytic leukemia complicated by liver cirrhosis and polycystic kidney by Yamane A1, Tsukamoto N, Saitoh T, Uchiumi H, Handa H, Karasawa M, Nojima Y, Murakami H.(PubMed)



Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment caused by systemic diseases

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

                     The Treatment

 Treatments in conventional medicine perspective
Pleural effusions caused by systemic diseases
Despite the low incidence (around 1%) of pleural effusions caused by systemic diseases, more often connective tissue diseases, such as rheumatoid arthritis or systemic lupus erythematosus.
Intra thoracic administration of cisplatin and sodium thiosulfate
In the study to to examine the pharmacokinetics and side effects of CDDP of Twenty-eight patients with malignant pleural effusion received instillation of cisplatin (CDDP) into the pleural cavity Thirteen patients received high-dose CDDP (120 mg/m2-160 mg/m2) in combination with sodium thiosulfate (STS), while 15 others received CDDP alone (80 mg/m2), found that malignant pleural effusion could be effectively treated by the instillation of CDDP 80 mg/m2 into the pleural cavity(104).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(104) http://www.ncbi.nlm.nih.gov/pubmed/3196043

The Smoothie of Green Tea and Grape for Prevention and Treatment of Bright's disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk of Bright's disease
Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the celery, apple with peels, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Bright's disease a disease involved chronic inflammation of the kidneys, characterized by the presence blood in the urine and is frequently accompanied by edema and hypertension.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemical epigallocatechin-3-gallate (EGCG), inhibited Bright's disease through regulation of oxidative stress and pro inflammatory cytokines NF-κB and Nrf2 signalling pathways(1).
Accoridng to the joint study led by the Shengjing Hospital of China Medical University, epigallocatechin-3-gallate (EGCG) also exhibited renoprotective effect through alleviated inflammatory responses alleviation and inhibited TGF-β/Smad signaling pathway in regulation of cell growth, differentiation in animal model(2).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry may be beneficiary for patients with Bright's disease(3). According to the University of Yamanashi, resveratrol, a natural polyphenolic phytoalexin, also showed to inhibited inflammation of Intraglomerular mesangial cells in kidney through regulation of NF-κB, a prototypical proinflammatory signaling pathway(4).
Furthermore, the phytochemical reduced damage to the kidneys.through attenuated the presence of abnormal quantities of protein in the urine, Dr. Nihei T and professors at the Tokyo Noko University, insisted(5).

The effectiveness of  Green Tea and Grape may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk and treatment of Bright's disease with little or no adverse effects.

People who are at high risk of Bright's disease due to aging, weaken reno function... should drink at least one serving daily and people with Bright's disease should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Epigallocatechin-3-Gallate Attenuates Oxidative Stress and Inflammation in Obstructive Nephropathy via NF-κB and Nrf2/HO-1 Signalling Pathway Regulation by Wang Y1, Wang B2, Du F1, Su X1, Sun G1, Zhou G1, Bian X1, Liu N3.(PubMed)
(2) Epigallocatechin-3-gallate attenuates unilateral ureteral obstruction-induced renal interstitial fibrosisin mice by Wang Y1, Wang B2, Du F2, Su X2, Sun G2, Zhou G2, Bian X2, Liu N2.(PubMed)
(3) Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy by Wu CC1, Huang YS2, Chen JS3, Huang CF4, Su SL5, Lu KC6, Lin YF7, Chu P3, Lin SH3, Sytwu HK8.(PubMed)
(4) Enhancement of NF-kappaB activity by resveratrol in cytokine-exposed mesangial cells by Uchida Y1, Yamazaki H, Watanabe S, Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J, Kitamura M.(PubMed)
(5) Inhibitory effect of resveratrol on proteinuria, hypoalbuminemia and hyperlipidemia in nephritic rats. by Nihei T1, Miura Y, Yagasaki K.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment caused by Tumors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

                     TheTreatment

 Treatments in conventional medicine perspective
Pleural effusion Treatment caused by  Pleural effusion Treatment caused by TumorsRadiographs may be continued used to monitor the progression of lung nodules, if the tumor does not double in size in less than a year and it does not become cancerous. Other wise surgery may be the only option, but the aim of the surgery is to spare the lung, unless it is absolutely necessary for it to be removed and depending to the patients conditions
1. Endoscopic cryotherapy
In a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy, found that endoscopic cryotherapy was found to be a safe and useful procedure in the management of endobronchial tumors although its efficacy and appropriate indications have yet to be determined in well-designed controlled studies(96).
2. Bronchotomy
Less than 1% of lung neoplasms are represented by benign tumors. Among these, hamartomas are the most common with an incidence between 0.025% and 0.32%. According to the study by the University of Messina, bronchotomy or parenchimal resection through thoracotomy should be reserved only for cases where the hamatoma cannot be approached through endoscopy, or when irreversible lung functional impairment occurred after prolonged airflow obstruction. Generally, when endoscopic approach is used, this is through rigid bronchoscopy, laser photocoagulation or mechanical resection. Here we present a giant EH occasionally diagnosed and treated by fiberoptic bronchoscopy electrosurgical snaring(97).
3. Pulmonary segmentectomy
Pulmonary segmentectomy has been recognized as an operative option for complete resection of early-stage lung cancer in patients with poor pulmonary function. According to the study by, transbronchial indocyanine green injection into the relevant bronchus with the use of an infrared thoracoscope allows identification of intersegmental lines and planes during thoracoscopic segmentectomy(98).
4. Lobectomy
In the study to assess 14,473 patients who met our inclusion criteria, lobectomy conferred superior unadjusted overall (p < 0.0001) and cancer-specific (p = 0.0053) 5-year survival compared with segmentectomy. Even after adjusting for patient factors, tumor characteristics, and geographic location, we noted that patients who underwent lobectomy had superior overall and cancer-specific survival rates, regardless of tumor size(99).
5. Sleeve resection
There is a report of a 75-year-old man complained of sputum and was referred to our department. His sputum cytology was class III. Chest X-ray and computed tomography showed no abnormalities, but bronchoscopy revealed an elevated lesion in the membranous portion of the left main bronchus, which was pathologically diagnosed as squamous cell carcinoma in situ. Since bronchoscopy revealed no other lesions in the visible parts of the airway, it was considered to be a solitary, early lung cancer, and sleeve resection of the left main bronchus was performed(100).
6. Completion pneumonectomy (CP)
Completion pneumonectomy (CP) is a difficult operation in which the surgeon must use techniques such as intrapericardial ligation of the pulmonary vessels. There is a case of CP for a patient with recurrent lung cancer. A 63-year-old man was admitted to our hospital for evaluation of abnormal shadows in the right lung field in October 2002. Right middle lobectomy with mediastinal lymph node dissection had been performed in February 1993. Computed tomography (CT) revealed a hilar mass in the right upper lobe the day after admission. Bronchofiberscopic cytology revealed squamous cell carcinoma. Right completion pneumonectomy was performed on suspicion of metachronous multiple lung cancers 4 days later. Histopathologically, resected specimens represented adenosquamous carcinoma similar to the prior lesion from the middle lobe, and examination revealed that the tumor represented a recurrence following middle lobectomy. The patient remains well as of 19 months postoperatively(101).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Thursday, March 24, 2016

The Smoothie of Cooked Tomato, broccoli and Orange Juice for Prevention and Treatment of Hyperalbuminemia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of 
Hyperalbuminuria 
Yield: 2 servings (about 8 ounces each)
1 1/4 cups tomato
1/2 cup broccoli
1 cup organic orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Albuminuria  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Cooked Tomato, broccoli and Orange Juice may be the next generation of natural ingredients for prevention and treatment of Albuminuria due to kidney decline

Albuminuria is a medical condition with too much protein in the urine, found
typically inpatients with kidney diseases. According to the Brigham and Women's Hwayospital, higher derivative vitamin A, beta-carotene, intake may reduce risk for Glomerular Filtration Rate (GFR) decline(1).

Lycopene, a chemically a carotene, also exhibited anti nephrotoxicity through anti proinflammatory pathways(3),

Coenzyme Q10, antioxidant found abundantly in broccoli may prevent or minimize cyclosporine nephrotoxicity through its antioxidant effect(4).
Dr. Ishikawa A and Dr. Homma Y. professors a the the University of Tokyo said, "Ubiquinol, the reduced form of coenzyme Q10 ......an antioxidants, may have potential for preventing CyA nephrotoxicity"(5).
In type 2 diabetes model, intake of supplement of coenzyme Q10 exhibited anti renal mitochondrial dysfunction caused by diabetic induced nephropathy(6).

Free radical scavengers vitamin C (Orange)  intake, increased plasma and renal cortical vitamin C or E content in prevention of renal injury(7) and development of diabetic nephropathy(9).
According to the Yonsei University Wonju College of Medicine, vitamin C exhibited anti oxidative stress in ameliorated albuminuria and renal sclerosis in experimental diabetic rats(8).

The effectiveness of Cooked Tomato, broccoli and Orange Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Albuminuria with little or no adverse effects.

People who are at high risk of Albuminuria due to aging, weaken renal function... should drink at least one serving daily and women with Albuminuria should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary as overweight and obesity are well-established risk factors for cardiovascular disease and decline in kidney function(2) 


References
(1) Associations of diet with albuminuria and kidney function decline. by Lin J1, Hu FB, Curhan GC.(PubMed)
(2) Association between body mass index and CKD in apparently healthy men by Gelber RP1, Kurth T, Kausz AT, Manson JE, Buring JE, Levey AS, Gaziano JM.(PubMed)
(3) Nrf2/HO-1 signaling pathway may be the prime target for chemoprevention of cisplatin-induced nephrotoxicity by lycopene. Sahin K1, Tuzcu M, Sahin N, Ali S, Kucuk O.(PubMed)
(4) Effect of reduced form of coenzyme Q10 on cyclosporine nephrotoxicity by Sato T1, Ishikawa A, Homma Y.(PubMed)
(5) Beneficial effect of ubiquinol, the reduced form of coenzyme Q10, on cyclosporine nephrotoxicity by Ishikawa A1, Homma Y.(PubMed)
(6) Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes by Sourris KC1, Harcourt BE, Tang PH, Morley AL, Huynh K, Penfold SA, Coughlan MT, Cooper ME, Nguyen TV, Ritchie RH, Forbes JM.(PubMed)
(7) Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes by Craven PA1, DeRubertis FR, Kagan VE, Melhem M, Studer RK.(PubMed)
(8) Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats by Lee EY1, Lee MY, Hong SW, Chung CH, Hong SY.(PubMed)
(9) Effect of vitamin E and vitamin C supplementation on antioxidative state and renal glomerular basement membrane thickness in diabetic kidney by Kedziora-Kornatowska K1, Szram S, Kornatowski T, Szadujkis-Szadurski L, Kedziora J, Bartosz G.(PubMed)

The Smoothie of Banana, Avocado and Herbal Ginger Tea for Prevention and Treatment of Hyperemesis gravidarum in Pregnancy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Hyperemesis gravidarum(Liver disease)

Yield: 2 servings (about 8 ounces each)
1 cup banana
1/2 cup avocado
1 cup herbal ginger tea

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of intrahepatic cholestasis of pregnancy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hyperemesis gravidarum of pregnancy is a medical condition with severe nausea, vomiting, weight loss, and electrolyte disturbance during pregnancy. The prevalence of hyperemesis gravidarum of 
pregnancy, may be associated to the presence of serum levels of neopterin, as a marker for immune system activation, inflammatory markers and oxidative stress(1)(2), particular Vitamin E, E equivalent, vitamin C, carotene and vitamin A levels(3).

Recent studies back by well known institutions proposed, Banana(7), Avocado(7) and Herbal Ginger Tea(4) may be the next generation of natural ingredients for prevention and treatment of hyperemesis gravidarum.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc. According to the University of Copenhagen, powdered root of ginger in daily doses of 1 g during 4 day, scored an significantly geater relief of the symptoms hyperemesis gravidarum in comparison to placebo(4).
Dr. Sonkusare S. professor at the Melaka Manipal Medical College, said, "The management of the (hyperemesis gravidarum)condition involves symptomatic treatment along with antiemetic, pyridoxine and thiamine. Important role of alternative therapies like ginger and P6 acupoint stimulation in the treatment of hyperemesis has been identified"(5).
Truly, the search of Medline, Embase, The Cochrane Library, and other important databases up to September 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review) by Festin M, professor at the Philippine General Hospital, suggested, alternative medicine of ginger root may also be effective for reduced risk and treatment of hyperemesis gravidarum when used combination with acupressure; acupuncture; corticosteroids; metoclopramide; ondansetron; prochlorperazine; promethazine; and pyridoxine (vitamin B6)(6).

Pyridoxine, also known as vitamin B6 found abundantly in bananas, and avocados is also found to associate to reduce risk and treatment of  Hyperemesis gravidarum(7).
According to the case of Naval Medical Center, in a double-blind, randomized, controlled trial in which women with nausea and vomiting of pregnancy, showed that the combination of pyridoxine and doxylamine relieved symptoms of nausea and emesis in pregnancy but lesser than those of ondansetron(8).

The effectiveness of Banana, Avocado and Herbal Ginger Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and  treatment of hyperemesis gravidarum with little or no adverse effects.

Women who are at high risk of hyperemesis gravidarumdue to family history, previous pregnancy..... should drink at least one serving daily and women with hyperemesis gravidarumshould drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination


References
(1) Serum levels of neopterin, inflammatory markers and oxidative stress indicators in hyperemesis gravidarum by Tunc SY1, Agacayak E1, Budak S2, Tunc N3, Icen MS1, Findik FM1, Ekinci A4, Gul T1.(PubMed)
(2) The oxidative stress index increases among patients with hyperemesis gravidarum but not in normal pregnancies by Yilmaz S, Ozgu-Erdinc AS, Demirtas C, Ozturk G, Erkaya S, Uygur D.(PubMed)
(3) Dietary antioxidant levels in hyperemesis gravidarum: a case control study by Celik F1, Guzel AI, Kuyumcuoglu U, Celik Y.(PubMed)
(4) Ginger treatment of hyperemesis gravidarum by Fischer-Rasmussen W1, Kjaer SK, Dahl C, Asping U.(PubMed)
(5) Hyperemesis gravidarum: a review. by Sonkusare S1.(PubMed)
(6) Nausea and vomiting in early pregnancy by Festin M1.(PubMed)
(7) [Treatment of hyperemesis gravidarum with combined inositol and pyridoxine].[Article in Italian] by BALESTRI F.(PubMed)
(8) Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial by Oliveira LG1, Capp SM, You WB, Riffenburgh RH, Carstairs SD.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment caused by Liver disease (cirrhosis)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

                     TheTreatment

 Treatments in conventional medicine perspective
Pleural effusion caused by Liver disease (cirrhosis)
Treatments of cirrhosis depend not only on the underlined causes but also the stages of the diseases
A.1. Alcohol causes of cirrhosis
If the the disease is caused by excessive alcohol drinking, patients will be asked to stop drinking. with help from the professional teams and certain medication. The long-term management of alcoholic liver disease stresses the following(82).
(1) Abstinence of alcohol (Grade 1A), with referral to an alcoholic rehabilitation program;
(2) Adequate nutritional support (Grade 1B), emphasizing multiple feedings and a referral to a nutritionist; (3) Routine screening in alcoholic cirrhosis to prevent complications;
(4) Timely referral to a liver transplant program for those with decompensated cirrhosis;
(5) Avoid pharmacologic therapies, as these medications have shown no benefit.
But according to the study by the Catholic University of Rome, in the intervention to achieve alcohol abstinence represents the most effective treatment for alcohol-dependent patients with liver cirrhosis by investigating the effectiveness and safety of Baclofen, is a GABA(B) receptor agonist in achieving and maintaining alcohol abstinence in patients with liver cirrhosis, showed that baclofen is effective at promoting alcohol abstinence in alcohol-dependent patients with liver cirrhosis. The drug is well tolerated and could have an important role in treatment of these individuals(83).
A.2. Obesity and Fatty liver
The prevalence of overweight and obesity are increasing in World wide, especially in the Emerging world, as a result of recently economic prosperity.
Obesity is defined as a medical condition of excess body fat accumulated overtime. Overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. In US, 68% of population are either overweight or obese. According to the study by Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital, for age-specific subgroup analyses, both overweight and obesity increased more rapidly in the toddler stage than in other developmental stages. Toddlers and urban boys were at particularly high risk; the prevalence in these groups increased more rapidly than in their counterparts(84).
The Obesity Society and the American Society of Hypertension agreed to jointly sponsor a position paper on obesity-related hypertension to be published jointly in the journals of each society(2). Other researchers suggested that in light of the worldwide epidemic of obesity, and in recognition of hypertension as a major factor in the cardiovascular morbidity and mortality associated with obesity(85).
Recent study showed that evidence has emerged for an association between genetic variability at the APOA5 locus and increased risk of obesity and metabolic syndrome(86).
Fatty liver disease is defined as a condition of accumulation of fat in the liver, including people who drink little or no alcohol (Non alcohol fatty disease) or who are excessive alcohol drinking (Alcohol fatty liver disease). The disease can even occur after a short period of heavy drinking (acute alcoholic liver disease). More than 15 million people in the U.S. either abuse or overuse alcohol with fatty liver diseases with fat makes up 5-10 percent of liver weight.
Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of clinical conditions, actually representing an emerging disease of great clinical interest(87)
There is no standard treatment in conventional medicine. If you are obese, you are advised to lose weight. If excessive drinking alcohol is the cause, you are advised to stop drinking.
Some researchers suggested that Vitamin E plus C combination treatment is a safe, inexpensive and effective treatment option in patients with fatty liver disease, with results comparable to those obtained with ursodeoxycholic acid(88). But some researchers suggested that Neither vitamin E nor metformin was superior to placebo in attaining the primary outcome of sustained reduction in ALT level in patients with pediatric NAFLD(89).
In traditional Chinese medicine, fatty liver is associated closely to obesity, as a result of over intake of “bad” fat and excessive alcohol drinking. Even though fatty liver is a result of too much fat, but trying to eliminate all fats from the diet won’t help to prevent or relieve the disease as malnutrition can also trigger fatty liver as fat and protein stored elsewhere in the body move to the liver for storage and conversion to energy as needed. That’s why some women who eat almost nothing but vegetables can also develop fatty liver(90).
Many traditional Chinese medicine practitioners believe, no way that one can lose weight if fatty liver diseases are not cured. Syndromes of fatty liver could be typed into 4 TCM types of the asthenia Pi-Shen with Gan-stagnation type, the asthenia Pi-Shen type, the asthenia Pi with phlegm-heat type and the unclassified type. Among them the asthenia Pi-Shen with Gan-stagnation type was the commonest one, which accounted to 62.32%(91).
Dr. Liu T, and the research team at the Shanghai University of Traditional Chinese Medicine, in the study to explore the pathogenesis of nonalcoholic fatty liver (NAFL) in traditional Chinese medicine (TCM) by comparing the therapeutic efficacy of methods for fortifying the spleen and replenishing qi, warming yang and fortifying the spleen and warming yang to move water, showed that body weight, liver and epididymal fat indexes and liver TAG level of rats all significantly increased in the model group as compared with the normal group (P<0.05). Hepatic fatty infiltration, TAG concentration and the levels of serum TAG and ALT were significantly decreased in the LGZG and SZ groups when compared to those in the model group (P<0.05). Method of warming yang or moving water can promote the lipid metabolism. It may be an effective strategy in preventing and treating NAFL by treating with warming yang and moving water together(92)
Other studies showed that Zhi Zi has a very strong inhibitory action on lipidosis and inflammatory injury in the rat model of NAFLD. This mechanism may possibly be related to the inhibition of the free fatty acid metabolism pathway(93)).
In the study to investigate the effect of Cigu Xiaozhi pills on expression of tumor necrosis factor alpha (TNF-alpha) in rat with nonalcoholic steatoheptatitis (NASH), found that Cigu Xiaozhi pills can effectively treat experimental nonalcoholic steatohepatitis in rats, and its mechanism may be associated with ameliorating hepatocellular steatosis, removing the free radicals and enhancing the capability of anti-oxidation and anti-inflammatory(94).
Most people with fatty liver disease are experience no symptoms at all, but Fatty liver disease is associated with high blood pressure, heart disease and diabetes can, in time, cause life threatening cirrhosis of the liver. According to the article By Donald Norfolk, "Today, as a direct effect of the obesity plague, it's reckoned that one in five British adults is now suffering from fatty liver disease, unconnected with virus infections or heavy drinking. This malady, known medically as steatosis, is believed to affect 90 per cent of morbidly obese patients, in whom it may remain totally symptomless for many years"(95).

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(83) http://www.ncbi.nlm.nih.gov/pubmed/18068515
(69) http://www.ncbi.nlm.nih.gov/pubmed/12605067
(70) http://www.ncbi.nlm.nih.gov/pubmed/10930711
(71) http://www.ncbi.nlm.nih.gov/pubmed/22474979
(72) http://www.ncbi.nlm.nih.gov/pubmed/21213394
(84) http://www.ncbi.nlm.nih.gov/pubmed/23284829
(85) http://www.ncbi.nlm.nih.gov/pubmed/23282121
(86) http://www.ncbi.nlm.nih.gov/pubmed/23279260
(87) http://www.ncbi.nlm.nih.gov/pubmed/23278163
(88) http://www.ncbi.nlm.nih.gov/pubmed/16245220
(89) http://www.ncbi.nlm.nih.gov/pubmed/21521847
(90) http://www.ncbi.nlm.nih.gov/pubmed/15768875
(91) http://live.shanghaidaily.com/column_detail.asp?type=column&id=718
(92) http://www.ncbi.nlm.nih.gov/pubmed/23073195
(93) http://www.ncbi.nlm.nih.gov/pubmed/22594108
(94) http://www.ncbi.nlm.nih.gov/pubmed/20707200