Medical Advisor Journals

Thursday, April 21, 2016

The Best Smoothie of Flax seed, Cabbage Leaf, Vitex agnus(Chasteberry) extract and avocado for Prevention and Treatment of Breast engorgement

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Breast engorgement
1/2 cup flaxseed
6 mg Vitex agnus extract
1 1/2 cooked cabbage leaf
1 cup organic avocado juice

The finding of a natural source for reduced risk and treatment of Breast engorgement has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(such as Ginger, Alfalfa Sprout and Orange) for reduced risk and treatment of Breast engorgement.

Breast engorgement is the painful swelling with overfilling of the breasts with milk or extra blood and lymph fluids in the breast tissue.
Applying cabbage leaf may benefits for women with breast engorgement(2) on relieving discomfort and decreasing tissue hardness, according to the Northern Territory University in Darwin(1).

Dr. Lim AR and colleagues led by the Korea Institute of Oriental Medicine Daejeon, suggested that cabbage compression early breast care (CCEBC) sginificantly effect on breast pain, breasthardness with general nursing breast care (GNBC) in primiparous women after cesarean birth(3).

Furthermore, a randomized, controlled trial conducted to evaluate the effect of cabbage leaves on mothers' perceptions of breast engorgement said,"The experimental group tended to report less breast engorgement, but this trend was not statistically significant. At six weeks, women who received the cabbage leafapplication were more likely to be breastfeeding exclusively,"(4).

Flaxseed oil, an extracted from the seeds of the flax plant (Linum usitatissimum) contained both omega-3 and omega-6 fatty acids may be effective in reduced breast pain for women with Breast engorgement. According to the joint study led by the Tabriz University of Medical Sciences, in randomized controlled trial on 159 women, Flaxseed are effective in short-term period in decreasing cyclical mastalgia(5).

The Memorial Sloan-Kettering Cancer Center study in review the effectiveness of flaxseed in of the literature of data bases suggetsed that the seed may benefit women with cyclic mastalgia (breast pain) due to the efficacy of alpha-linoleic acid(6).

Dr. Rosolowich V and colleagues at the Winnipeg Regional Health Authority, said, "Flaxseedshould be considered as a first-line treatment for cyclical mastalgia"(7).

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belongings to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and is considered as Queen herb in treating menstrual problems. The herbal extract has found effectively in reduced pain in women with Breast engorgement(5).

According to the Royal Melbourne Institute of Technology-University, the popular herbal treatment, Vitex agnus-castus L. showed to reduce serum prolactin levels and ameliorate cyclic mastalgia in comparable to bromocriptine(8).

Dr. Halaska M and colleafues at the I. gynek.-porod. klinika 1. said, " Intensity of breast pain diminished quicker with .Vitex agnus castus (VACS) extract group. The tolerability was satisfactory. We found VACS to be useful in the treatment of cyclical breast pain in women"(9).

Vitamin E, a fat soluble viatmin found abundantly in avocado may also be used as natural supplemental agents for treatment of cyclic mastalgia, according to the study led by Hamadan University of Medical Sciences(10).

The evaluation the effectiveness of vitamin E, evening primrose oil (EPO), and the combination of vitamin E and EPO for pain control in women with cyclical mastalgiam conducted by the Mayo Clinic said,"Daily doses of 1,200 IU vitamin E, 3,000 mg EPO, or vitamin E and EPO in combination at these same dosages taken for six months may decrease the severity of cyclical mastalgia"(10).

The effectiveness of Flax seed, Cabbage Leaf, Vitex agnus extract and avocado may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Breast engorgement with little or no adverse effects.

Women who are at increased risk of Breast engorgement due to family history,.....may drink at least one serving daily and women with Breast engorgement may drink as much as they can, depending to the digestive toleration.
Topical administration of cabbage leaf are recommended.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Effects of cabbage leaf extract on breast engorgement by Roberts KL1, Reiter M, Schuster D.(PubMed)
(2) Cabbage leaves vs hot and cold compresses in the treatment of breast engorgement by Arora S1, Vatsa M, Dadhwal V.(PubMed)
(3) Cabbage compression early breast care on breast engorgement in primiparous women after cesarean birth: a controlled clinical trial by Lim AR1, Song JA1, Hur MH1, Lee MK1, Lee MS2.(PubMed)
(4) Do cabbage leaves prevent breast engorgement? A randomized, controlled study by Nikodem VC, Danziger D, Gebka N, Gulmezoglu AM, Hofmeyr GJ.(PubMed)
(5) Effects of Vitex agnus and Flaxseed on cyclic mastalgia: A randomized controlled trial by Mirghafourvand M1, Mohammad-Alizadeh-Charandabi S2, Ahmadpour P3, Javadzadeh Y4.(PubMed)
(6) Flax and flaxseed oil (Linum usitatissimum): a review by the Natural Standard Research Collaboration by Basch E1, Bent S, Collins J, Dacey C, Hammerness P, Harrison M, Smith M, Szapary P, Ulbricht C, Vora M, Weissner W; Natural Standard Resource Collaboration(PubMed)
(7) Mastalgia.[Article in English, French]by Rosolowich V1, Saettler E, Szuck B, Lea RH, Levesque P, Weisberg F, Graham J, McLeod L, Rosolowich V; Society of Obstetricians and Gynecologists of Canada (SOGC).(PubMed)
(8) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(9) [Treatment of cyclical mastodynia using an extract of Vitex agnus castus: results of a double-blind comparison with a placebo].[Article in Czech]by Halaska M1, Raus K, Bĕles P, Martan A, Paithner KG.(PubMed)
(10) Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study by Pruthi S1, Wahner-Roedler DL, Torkelson CJ, Cha SS, Thicke LS, Hazelton JH, Bauer BA.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary arterial hypertension – The Symptoms

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

Pulmonary vascular disease: Pulmonary arterial hypertension

Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

Pulmonary arterial hypertension is a subgroup of a specific subgroup of pulmonary hypertension (PH) defined as a condition of slowly progressive disorder as a result of abnormally high blood pressure in the blood vessel, including pulmonary artery, pulmonary vein, or pulmonary capillaries, that carries blood from the heart to the lungs due to narrowing in diameter of most of the very small arteries throughout the lungs of that increased resistance to blood flow, leading to right heart failure and death. Because the phrase pulmonary arterial hypertension is long and pulmonary hypertension is a bit shorter the phrase pulmonary hypertension is often used in place of pulmonary arterial hypertension(a).According to statistic, approximately over 1,000 new cases of pulmonary arterial hypertension are diagnosed each year, In the United States alone.

The Symptoms

1. Depressive disorder
In the study to screen Consecutive outpatients with PAH of a A group of 100 patients (88% women, 50% with idiopathic PAH) (idiopathic; or associated with scleroderma, congenital heart disease, or anorexiant use) seen in two university PAH clinics, showed that 5% of subjects had symptoms suggestive of major depressive disorder; 40% had mild-to-moderate depressive symptoms; and 45% had no-to-minimal depressive symptoms(1).
2. Other symptoms
In the study to use cluster analysis to describe the symptom profile in PAH and differences in the health outcomes of health status, health-related quality of life (HRQoL) and psychological states in the cluster groups, by University of Pennsylvania, School of Nursing, found that of the 151 participants, the mean age was 53.5 ± 15.1 with the majority female (n = 128, 85%). Fifty-eight (41%) were disabled and 67 (44%) were Functional Class IV. The most prevalent symptoms were shortness of breath with exertion (n = 149, 99%) and fatigue (n = 144, 93%). Three clusters emerged: Cluster 1 diffuse symptoms (n = 93), Cluster 2 severe cardiopulmonary symptoms (n = 32) and Cluster 3 moderate cardiopulmonary symptoms (n = 26). Overall, on the SF-36 the participants had poor general health, reduced physical function, role physical, vitality, and a low composite score for physical health. On the POMS the sample had limited vigor and increased fatigue. Other study showed that
The most common symptom of PH is breathlessness on exertion. Syncope may be the presenting symptom especially in children. Other PH symptoms include: angina pectoris, palpitations, dry cough, exertional nausea and vomiting(3).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://pulmonaryhypertensionrn.com/ph-vs-pah/
(1) http://www.ncbi.nlm.nih.gov/pubmed/20587763
(2) http://www.ncbi.nlm.nih.gov/pubmed/22357779
(3) http://www.ncbi.nlm.nih.gov/pubmed/23477017

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Misdiagnosis and Delay diagnosis

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).

Misdiagnosis and Delay diagnosis

1. Polyarticular gout
Polyarticular gout, a inflammatory condition with painful crystals forming in the joints has been found to be misdiagnosed as Rheumatoid Arthritis in elderly of that can constitute to poor treatment as well as failure to recognize underlying renal insufficiency, and increased cardiac risks(75), according to the Albert Einstein College of Medicine.

2. Hypercalcemia and Lytic Bone Lesions Masquerading Inflammatory Arthritis
According to the Mashhad University of Medical Sciences, a 50-year-old woman with hypercalcemia, lytic bone lesions and inflammatory arthritis of both hands was misdiagnosed as rheumatoid arthritis due to the presence of perparathyroidism in rheumatologic manifestations(76).

3. Systemic sclerosisSystemic sclerosis (SSc) is an autoimmune disease of the connective tissue may be misdiagnosed as rheumatoid arthritis. According to the Dr. Horimoto AM and Dr. Costa IP, arthritis, clinically observed, may be a feature often found in patient with Systemic sclerosis, often leading to early misdiagnosis with rheumatoid arthritis (RA)(77).

4. Jaccoud's arthropathy (JA)
Jaccoud's arthropathy (JA), a clinical situation foundt mostly in patient withsystemic lupus erythematosus (SLE) is found to be misdiagnosed as RA, due to swan neck," ulnar deviation and "Z-thumb which overlap with symptoms of patient with RA, according to the joint study lead by the Universidade Federal da Bahia, Salvador(78).

In fact, according to the joint study by the University of Texas Southwestern Medical Center and Victoria Hospital, the misdiagnosis of the atypical Infections versus Inflammatory Conditions of the Hand due to some similarity to inflammatory conditions regarding their clinical and imaging finding is rare but delay diagnosis can increase risk of severe bone and joint destruction, and higher morbidity(79).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(75) Misdiagnosis of rheumatoid arthritis in an elderly woman with gout by Sewell KL1, Petrucci R, Keiser HD(PubMed)
(76) Hypercalcemia and Lytic Bone Lesions Masquerading Inflammatory Arthritis Treated as Rheumatoid Arthritis by Salari M1, Aboutorabi RB2, Rezaieyazdi Z1(PubMed)
(77) [Overlap between systemic sclerosis and rheumatoid arthritis: a distinct clinical entity?][Article in Portuguese] by Horimoto AM1, Costa IP2.(PubMed)
(78) Severe Jaccoud's arthropathy in systemic lupus erythematosus by Santiago MB1,2, Galvão V3, Ribeiro DS3, Santos WD3, da Hora PR3, Mota AP3, Pimenta E3, Oliveira I4, Atta AM4, Reis MG5, Reis EA5, Lins C3(PubMed)
(79) Atypical Infections versus Inflammatory Conditions of the Hand: The Role of Imaging in Diagnosis by Soldatos T1, Omar H, Sammer D, Chhabra A.(PubMed)

The Smoothie of Ginger, Alfalfa Sprout Juice and Orange Juice for Prevention and Treatment of Menorrhagia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Menorrhagia
1 cup of organic orange juice
1 large slice ginger root
1 cup alfalfa sprout juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Menorrhagia has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(such as Ginger, Alfalfa Sprout and Orange) for reduced risk and treatment of Menorrhagia

Menorrhagia is a menstrual condition of abnormal heavier vaginal bleeding. According to the bioflavonoids and vitamin C(1) may offer the potential treatment by preventing the breaking of vaginal capillaries inducing heavy bleeding(2).

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil. According to the Iran University of Medical Sciences, application of ginger in 92 young women who experienced HMB significantly reduced the level of menstrual blood loss during the three intervention cycles in ginger-receiving group(3).

Phytoestrogen found in alfalfa sprout juice expressed both estrogenic and anti estrogenic effect may also benefit women with heavy menstrual bleeding due to hormone imbalance(4). According to Fatih Yildiz, as in functional foods, intake of phytoestrogen may contribute to the deduction of heavy bleeding due to estrogen deficiency(5)(6).

Vitamin C, a water soluble vitamin found abundantly in orange may also be used to treat heavy
bleeding due to weaken uterine capillaries due to aging or vitamin C deficiency(1)(7). According to
the Burn Center-BG Trauma Center Ludwigshafen, high dose of vitamin C significantly reduced capillary leakage after burn plasma transfer in animal model(7).
In fact, the effectiveness of vitamin C in reduced risk of heavy bleeding may be due to its effect in wound healing of the breaking off of endometrial lining during menstruation(8)(9).

The effectiveness of Ginger, Alfalfa Sprout Juice and Orange Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Menorrhagia with little or no adverse effects.

Women who are at increased risk of Menorrhagia due to family history, aging,.....may drink at least one serving daily and women with Menorrhagia may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

References
(1) Functional menorrhagia: treatment with bioflavonoids and vitamin C. by COHEN JD, RUBIN HW.(PubMed)
(2) Capillary strength of women with menorrhagia by ALAN C, CLEMETSON B, BLAIR LM.(PubMed)
(3) Effect of ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-controlled, randomized clinical trial by Kashefi F1, Khajehei M, Alavinia M, Golmakani E, Asili J.(PubMed)
(4) Phytoestrogen content and estrogenic effect of legume fodder by Saloniemi H1, Wähälä K, Nykänen-Kurki P, Kallela K, Saastamoinen I.(PubMed)
(5) Phytoestrogens In Functional Foodsedited by Fatih Yildiz
(6) The New Harvard Guide to Women's Health By Karen J. Carlson, Stephanie A. Eisenstat, Terra Diane Ziporyn
(7) High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats by Kremer T1, Harenberg P, Hernekamp F, Riedel K, Gebhardt MM, Germann G, Heitmann C, Walther A.(PubMed)
(8) Vitamin C and human wound healing by Ringsdorf WM Jr, Cheraskin E.(PubMed)
(9) Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies by6 Ellinger S1, Stehle P.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary embolism- Treatment In Herbal and TCM medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

Pulmonary vascular disease: Pulmonary embolism

Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

Pulmonary embolism (PE) is defined as a condition of blockage of blood flow due to a blood clot of either in main artery of the lung or somewhere else in the body. In most cases, it is in the deep veins of the legs or pelvic. The disease is a common and affect as many as 500,000 persons annually in the United States

The Treatment

B. In Herbal medicine perspective
In the study to investigate the effect of aqueous extract of several herbs on human platelet aggregation in vitro of of 28 herbs/nutriceuticals investigated, camomile, nettle alfalfa, garlic and onion exhibited most significant anti-platelet activity (>or=45% inhibition), indicated that queous extracts of alfalfa, fresh nettle, and camomile inhibited ADP induced-platelet aggregation by 73, 65 and 60%, respectively, compared with control (P < 0.05). Camomile and alfalfa inhibited collagen-induced platelet aggregation by 84 and 65%, respectively, but nettle could not inhibit collagen-induced aggregation. In contrast, nettle was the most potent inhibitor (66%) of whole blood aggregation induced by collagen, followed by alfalfa (52%), and camomile (30%) compared with control (P < 0.05). None of these three herbs however could inhibit arachidonic acid or thrombin induced platelet aggregation. Camomile and alfalfa strongly inhibited thromboxane B2 synthesis induced by ADP or collagen, but nettle had no effect. Alfalfa and nettle increased cGMP levels in platelets by 50 and 35%, respectively, compared with the control (1.85 +/- 0.23 nM) (P < 0.005). All these data indicate that camomile, nettle and alfalfa have potent anti-platelet properties, and their inhibitory actions are mediated via different mechanisms(53).
C. In traditional Chinese perspective
According to the China Academy of Traditional Chinese Medicine, in the study of Herbs of activating blood circulation to remove blood stasis, drugs of anti-hyperviscosemia, anti-coagulants, anti-platelet drugs, anti-thrombotics, vasodilators, endothelial cell protectors and anti-arthrosclerosis should be considered as hemorheologicals due to the actions in keeping blood fluidity and in maintaining normal vascular functions. Hemorheologicals are importance for and aging and life-threatening diseases. Blood stasis syndrome is a common pathological syndrome in the elderly. In traditional Chinese medicine, the treatment for the syndrome is by herbs which activates blood circulation to remove blood stasis. The herbs have the efficacy of improving hemorheological events. Therefore, the herbs are the source for developing hemorheologicals. Ligustrazine isolated from Chuangxiong is an example. It showed significant inhibition on shear induced platelet aggregation and on platelet intracellular calcium demonstrated by laser confocal microscope(54).

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(53) http://www.ncbi.nlm.nih.gov/pubmed/16287614
(54) http://www.ncbi.nlm.nih.gov/pubmed/11321431

Wednesday, April 20, 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The Diagnosis

The Diagnosis

If you are experience certain subtle symptoms, such as achy joints or a morning stiffness, etc,....you may be at the early stage onset of rheumatoid arthritis. If your doctor suspect that have develop RA because of some RA symptoms such as such as warmth, swelling and pain in the joints, after physical exam, certain blood tests may be necessary, including
1. Erythrocyte sedimentation rate
ESR is a a common hematology test to calculate the rate of red blood cells sediment in a period of one hour. According to Dr. Wolfe F said " ESR is sensitive to immunoglobulins and rheumatoid factor (RF),... but a a poorer measure of inflammation"(64a) and may be effected by other factors. Other clinical findings, the individual's health history, and results from laboratory tests are necessary, such as C-reactive protein(64a) to rule out a suspected diagnosis for the confirmation of the result. Dr Sokka T and Dr. Pincus T. normal ESR and CRPC-reactive protein, are seen in a substantial proportion of patients with RA.(65a)

2. C-reactive protein
A group of "acute phase reactants" protein produced by liver and found in patient with rheumatoid arthritis.,tends to elevate in case of inflammation. According to the Copenhagen University Hospital, oral nonsteroidal antiinflammatory drugs (NSAIDs) does not effects the levels of protein but may be constituted to the influence of NSAIDs on cardiovascular complications in patient with RA(66).

3. Test for Anemia
According to statistic, the prevalence of mild anemia characterized by low serum iron concentration ranged between 33% and 60% are found in patient with rheumatoid arthritis(67), such as aplastic anemia and iron deficiency anemia. In fact, patient with combination of RA and amenia are mostly experience severe forms of joint disease and improvement of anemia is found to contribute to over all quality of life (QOL) and response to RA therapy(67).

4. Anti-cyclic citrullinate d peptide (anti-CCP antibodies)
Cyclic citrullinated peptides (CCP) in most cases is ordered in conjunction with the test of rheumatoid factor in patient with RA. The positive find of anti-citrullinated peptide/protein antibodies may contribute to the presence of the early event in the disease(68). Dr van Venrooij WJ and the research team at the Radboud University said"...., the presence of these antibodies was highly predictive of and specific for RA, and illustrating the importance of ACPA"(69).
5. Rheumatoid factor
Rheumatoid factor test is a blood test to measure the antibody in patient with rheumatoid arthritis.
The study of 71 patients with rheumatoid arthritis and 25 control subjects. AIF-1 is found to associated with the pathogenesis of RA involved in the immunological process underlying RA(70).
Others such as elevation of interleukin-7 receptor (IL-7Ralpha)(71), interleukin-18(72),.... also involve in the presence of RA.
6. X ray
X ray may be important to determine the changes of bone mineral density. Patient with RA are found to have an lower BMD of that can lead to increased risk of major fracture and hip fracture(73). The family notebook suggested the relative change of Rheumatoid Arthritis found in X ray according to Dr. Kirwan J and Dr. Byron M, Watt I. include soft tissue swelling, joint space narrowing and erosive damage(74).
Arthritis Is Curable You Can Eliminate Osteoarthritis By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)
(64) Risk of rheumatoid arthritis following vaccination with tetanus, influenza and hepatitis B vaccines among persons 15-59 years of age by Ray P1, Black S, Shinefield H, Dillon A, Carpenter D, Lewis E, Ross P, Chen RT, Klein NP, Baxter R; Vaccine Safety Datalink Team.(PubMed)
(65) Can immunisation trigger rheumatoid arthritis? by D P Symmons and K Chakravarty(PubMed)
(64a) Comparative usefulness of C-reactive protein and erythrocyte sedimentation rate in patients with rheumatoid arthritis by Wolfe F1.(PubMed)
(65a) Erythrocyte sedimentation rate, C-reactive protein, or rheumatoid factor are normal at presentation in 35%-45% of patients with rheumatoid arthritis seen between 1980 and 2004: analyses from Finland and the United States by Sokka T1, Pincus T.(PubMed)
(66) Effect of nonsteroidal antiinflammatory drugs on the C-reactive protein level in rheumatoid arthritis: a meta-analysis of randomized controlled trials by Tarp S1, Bartels EM, Bliddal H, Furst DE, Boers M, Danneskiold-Samsøe B, Rasmussen M, Christensen R.(PubMed)
(67) Prevalence and outcomes of anemia in rheumatoid arthritis: a systematic review of the literature by Wilson A1, Yu HT, Goodnough LT, Nissenson AR.(PubMed)
(68) Anti-CCP antibodies: the past, the present and the future by van Venrooij WJ1, van Beers JJ, Pruijn GJ.(PubMed)
(69) Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis by Suwannalai P1, Trouw LA, Toes RE, Huizinga TW(PubMed)
(70) Expression of allograft inflammatory factor-1 in peripheral blood monocytes and synovial membranes in patients with rheumatoid arthritis by Pawlik A1, Kotrych D2, Paczkowska E3, Roginska D3, Dziedziejko V4, Safranow K4, Machalinski B5.(PubMed)
(71) Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis by Hartgring SA1, van Roon JA, Wenting-van Wijk M, Jacobs KM, Jahangier ZN, Willis CR, Bijlsma JW, Lafeber FP.(PubMed)
(72) Interferon-gamma-inducing activity of interleukin-18 in the joint with rheumatoid arthritis by Yamamura M1, Kawashima M, Taniai M, Yamauchi H, Tanimoto T, Kurimoto M, Morita Y, Ohmoto Y, Makino H.(PubMed)
(73) [Risk factors for bone mineral density changes in patients with rheumatoid arthritis and fracture risk assessment].[Article in Chinese] by Wang Y1, Hao YJ1, Deng XR1, Li GT1, Geng Y1, Zhao J1, Zhou W1, Zhang ZL1.(PubMed)
(74) The relationship between soft tissue swelling, joint space narrowing and erosive damage in hand X-rays of patients with rheumatoid arthritis by Kirwan J1, Byron M, Watt I.(PubMed)

The Smoothie of Orange, Yogurt, Honey and Ginger in Prevention and Treatment of Vaginal yeast infection

1 cup ginger herbal tea

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast, fungi, and mold that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that do not cause harmful effects, but overgrowth results in candidiasis(1)

The finding of a natural source for reduced risk and treatment of vaginal yeast infection to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Yogurt, make from whole milk may consist a powerful ingredient for prevention and treatment of Vaginal yeast infection as its promote the suppression of C. albicans growth through Lactobacillus colonization the in the reproductive tract(2).

The study of the Central Emek Hospital, Afula, Israel, insisted, "daily ingestion of 150 mL of yogurt, enriched with live L acidophilus, was associated with an increased prevalence of colonization of the rectum and vagina by the bacteria, and this ingestion of yogurt may have reduced episodes of BV."(3).

Vitamin C found abundantly in orange, a water soluble vitamin, as free radical scavengers and regenerated oxidized vitamin E for immune support may be a potential ingredient for treatment of vaginal yeast infection(4).
Feminella Vagi C, a commercial product of Vitamin C (Ascorbic Acid) exhibited anti bacterial vaginosis (BV) and/or mycotic infection activity when used conjunction with Nifuratel, Nistatin)(5) leading to higher percentage of clinically recovery (86.7% vs 84.6%), better microbiological cleaning (86.7% vs 82.1%) and longer effect of treatment.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat morning sickness, gastroparesis, constipation,...etc. According to the Teikyo University Institute of Medical Mycology, ginger essential oils, and particularly those from seed and air-dried rhizomes, had potent inhibitory activity, particular the 6]-shogaol constituent(6).

Dr. Giriraju A and Dr. Yunus GY. said, " 10% ethanolic ginger extract showed: (a) Maximum zone of inhibition of 8 mm, 14 mm, and 11 mm against S. mutans, C. albicans, and E. faecalis respectively. (b) MIC of 1.25%, 2.5%, and 2.5% against S. mutans, C. albicans, and E. faecalis respectively"(7).

Interestingly, the Institute of Veterinary Sciences University Ibn-KhadounTiaret, study suggested that use of ginger starch may allow honey benefit in constituted an alternative way against the resistance to antifungal agents(8).

The effectiveness of Orange, Yogurt, Honey and Ginger may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of vaginal yeast infection with little or no adverse effects.

Women who are at increased risk of vaginal yeast infection may drink at least one serving daily and women with vaginal yeast infection may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

References
(1) The Reader Guide To Cure Candidiasis: Testing Candidiasis by Kyle J. Norton

(2) Utility of the oestrogen-dependent vaginal candidosis murine model in evaluating the efficacy of various therapies against vaginal Candida albicans infection by Hamad M1, Muta'eb E, Abu-Shaqra Q, Fraij A, Abu-Elteen K, Yasin SR.(PubMed)

(3) Ingestion of yogurt containing Lactobacillus acidophilus compared with pasteurized yogurt as prophylaxis for recurrent candidal vaginitis and bacterial vaginosis by Shalev E1, Battino S, Weiner E, Colodner R, Keness Y.(PubMed)
(4) Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis by van Schalkwyk J1, Yudin MH2; Infectious Disease Committee, Yudin MH2, Allen V3, Bouchard C4, Boucher M5, Boucoiran I1, Caddy S6, Castillo E6, Kennedy VL2, Money DM1, Murphy K2, Ogilvie G1, Paquet C7, van Schalkwy JK1; Society of Obstetricians and Gynaecologists of Canada.(PubMed)
(5) [Multipurpose treatment of vaginal infections].[Article in Bulgarian] by Nikolov A, Masseva A, Shopova E, Georgiev S.(PubMed)
(6) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(7) Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: an in vitro study by Giriraju A1, Yunus GY.(PubMed)
(9) Additive potential of ginger starch on antifungal potency of honey against Candida albicans by Moussa A1, Noureddine D, Hammoudi SM, Saad A, Bourabeh A, Houari H(PubMed)