Thursday, April 28, 2016

The smoothie of celery, apple and green tea for Hypertensive complication caused by Nutcracker syndrome


Kyle J. Norton(Scholar), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Nutcracker syndrome is a vascular compression of the left renal vein between the superior mesenteric artery (SMA) and aorta, causing increased blood pressure inducing rupture of thin-walled veins to cause accumulation of haematuria. Surgical treatment may be the best option for patients with the syndrome(14)(15).
To reduce the complication of hypertension in induction of accumulation of haematuria, the following smoothie can be helpful.


Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. high blood pressure means raising pressure in your heart. If your blood pressure stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but also induced many irreversible adverse effects, including kidney damage.

The smoothie for people with Hypertensive complication caused by Nutcracker syndrome
Yield: 2 servings (about 8 ounces each)
3/4 cup celery
3/4 cup of apple with peel
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the celery, apple with peels, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Diet rich in fruits and vegetable and reduced intake of red meat, saturated fat and trans fat has shown to attenuated risk of hypertension(1). Recent study showed that celery(2) intake used conjunction with berries(3) and green tea(4) may be the potential drink for prevention and treatment of hypertension.

Celery is a species of Apium graveolens, belongings to the family Apiaceae, cultivated all around the globe as a vegetable. According to Chronic administration of hexanic, methanolic, and aqueous-ethanolic extracts of celery seed effectively exhibited an antihypertensive activity in chronic treatment of elevated BP in tested animals(5).

Dr. Dianat M and the research team at the Ahvaz Jundishapur University of Medical Sciences said," hydro-alcoholic celery leaf extract on systolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose"(6)

3‑n‑butylphthalide (NBP), an phytochemical found in celery seed used in traditional Chinese medicine exhibited significantly antihypertensive and attenuated progression of hypertensive effects through decreased oxidative stress and the expression of pro‑inflammatory cytokines(7).
Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. With phytochemical flavonoids, apple and its peel inhibited angiotensin converting enzyme (ACE) in promoted the development of high blood pressure, Dr Balasuriya N and Dr. Rupasinghe HP. Suggested(8)According to the Mount Sinai School of Medicine, "Flavonoid (found abundantly in fruits and vegetable)(10) intake has been inversely associated with mortality from coronary heart disease and stroke,..... Lowering blood pressure through increased dietary consumption of dietary antioxidants(such as flavonoid) may decrease the rate of end-organ damage that is secondary to hypertension"(9).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Epigallocatechin-3-O-gallate (EGCG), the main polyphenol presence in green tea is best known for its antioxidant and anti inflammatory effect. In animal model, the phytochemical exhibited anti hypertensive and progressive activity through reduction of oxidative stress in paraventricular nucleus of hypothalamus (PVN), the Xi'an Jiaotong University Health Science Center study showed(11).

Dr. Yarmolinsky J and the research team at the Federal University of Rio Grande do Sul, suggested that, intake of tea are shown to reduce blood pressure in individuals within prehypertensive and hypertensive ranges in the review of all relevant studies published from 1946 to September 27, 2013.(12).

Furthermore, green tea extract (GTE) inhibited the oxidative stress and ingiotensin (Ang) II induces endothelial dysfunction (ED) causes of hypertension through scavenging of superoxide anion generation, the University of Padova, insisted(13).

People who are at increased risk of hypertension caused by Nutcracker syndrome should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

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References

(1) Fruit and Vegetable Consumption and the Incidence of Hypertension in Three Prospective Cohort Studies by Borgi L1, Muraki I2, Satija A2, Willett WC2, Rimm EB2, Forman JP2.(PubMed)
(2) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(3) Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors by Toh JY1, Tan VM, Lim PC, Lim ST, Chong MF.(PubMed)
(4) Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome by Ihm SH1, Jang SW, Kim OR, Chang K, Oak MH, Lee JO, Lim DY, Kim JH.(PubMed)
(5) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(6) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(7) Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats by Zhu J1, Zhang Y1, Yang C1.(PubMed)
(8) Antihypertensive properties of flavonoid-rich apple peel extract by Balasuriya N1, Rupasinghe HP.(PubMed)
(9) Dietary flavonoids and hypertension: is there a link? by Moline J1, Bukharovich IF, Wolff MS, Phillips R.(PubMed)
(10) Antihypertensive effects of the flavonoid quercetin by Perez-Vizcaino F1, Duarte J, Jimenez R, Santos-Buelga C, Osuna A.(PubMed)
(11) Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension by Yi QY1, Qi J, Yu XJ, Li HB, Zhang Y, Su Q, Shi T, Zhang DM, Guo J, Feng ZP, Wang ML, Zhu GQ, Liu JJ, Shi XL, Kang YM.(PubMed)
(12) Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials by Yarmolinsky J1, Gon G2, Edwards P2.(PubMed)
(13) Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts by Antonello M1, Montemurro D, Bolognesi M, Di Pascoli M, Piva A, Grego F, Sticchi D, Giuliani L, Garbisa S, Rossi GP.(PubMed)
(14) Surgical treatment of posterior nutcracker syndrome presented with hyperaldosteronism by Deser SB1, Onem K2, Demirag MK3, Buyukalpelli R2.(PubMed)
(15) Laparoscopic Extravascular Stent Placement for Nutcracker Syndrome: A Report of 13 Cases by Wang SZ1, Zhang WX1, Meng QJ1, Zhang XP1, Wei JX1, Qiao BP1.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary veno-occlusive disease The Risk Factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

   Pulmonary vascular disease:  Pulmonary veno-occlusive disease 


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

Pulmonary veno-occlusive disease (PVOD) is an extremely rare form of pulmonary hypertension, affecting mostly in children and young adults as a result of a progressive obstruction of small pulmonary veins that leads to elevation in pulmonary vascular resistance and right ventricular failure.

                      The Risk factors

1. Gender
If you are male, you are at increased risk to develop Pulmonary veno-occlusive disease (PVOD), according to the study by research team lead by Wagenvoort CA(13).
2. Genetic abnormality
PVOD is characterized by alterations of circulating cytotoxic cell subpopulations and by epigenetic dysregulation within the GNLY gene, according to the study by the Department of Pneumology and Intensive Care, Hôpital Antoine Béclère, Assistance Publique(14). Other study reported a patient with documented PVOD whose mother had severe pulmonary hypertension. Sequencing of the patient’s BMPR2 coding region revealed a del44C mutation in Exon 1 that is predicted to encode for a truncated proteindevelopment of PVOD(14a)
3. Injury
Injury may also have caused the arterialization of the venous walls, a common finding that cannot always be explained by distal narrowing of larger veins. Although the etiology of pulmonary veno-occlusive disease is obscure, it seems increasingly likely that multiple noxious agents may induce this condition(15).
4. Fenfluramine exposure
There is a report of a case of PVOD in a patient with a history of fenfluramine exposure, therefore suggesting a possible association between anorexigen exposure and PVOD(16).
5. Chemotherapy and bone marrow transplantation
PVOD has been reported in association with various chemotherapy regimens including bleomycin, bis-chloronitrosourea and mitomycin(17)
6. After bone marrow transplantation
There is areport of a case of pulmonary veno-occlusive disease (PVOD) following allogeneic bone marrow transplantation (BMT) for the treatment of acute myeloid leukemia (AML) from an HLA mismatched mother using a reduced-intensity conditioning (RIC) regimen including gemtuzumab ozogamicin(18). 

Wednesday, April 27, 2016

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Psychological intervention

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).



                            The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.2. Psychological intervention
Psychological intervention may be useful to reduce depression, anxiety and other symptoms in patient with RA due to associate to pain, distress and disability and reduced quality of life style in chronic pain patients, the University College London suggested(223). Dr. Matcham F and the research team at the joint study lead by King's College London said" The most consistent relationship was found between mood and fatigue, with low mood frequently associated with increased fatigue. Some evidence also highlighted the relationship between RA-related cognitions (such as RA self-efficacy) and fatigue, and non-RA-cognitions (such as goal ownership) and fatigue(224), as there is a psychological correlates of fatigue in rheumatoid arthritis.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offerrecommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References

(223) Psychological therapies for the management of chronic pain (excluding headache) in adults by Williams AC1, Eccleston C, Morley S.(PubMed)
(224) Psychological correlates of fatigue in rheumatoid arthritis: a systematic review by Matcham F1, Ali S2, Hotopf M3, Chalder T4.(PubMed)

The Smoothie of Green Tea, Coffee and Tomato for Prevention and Treatment of Liver Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Liver cancer
Yield: 2 serving (about 8 ounce each)
3/4 cup tomato
1/2 cup coffee
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Liver cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by renowned institutions, conveyed that Green Tea(3), Coffee(4) and Tomato(7) may be holding a key for extracting natural ingredient for reduced early onset and treatment of Liver cancer.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Tohoku University Graduate School of Medicine, Regular comsumption of green tea is associated with a reduced risk of liver cancer incidence(1).

Liver cancer is defined as a condition of out of controlled growth of hepatocellular cells in the liver. Since the organ is a soft tissue with less nerve, most liver cancer patient are diagnosed in the later stage of the cancer. According to the statistic, liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide. Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.

The Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University study in the review of nine prospective cohort articles involving 465,274 participants and 3694 cases of liver cancer from China, Japan, and Singapore, suggested that green tea exhibited a preventive effects on the risk for liver cancer in female Asian populations. However, additional studies are needed to make a convincing case for this association(2).

Epidemiologically, according to Dr. Fon Sing M and colleagues, consumption of green tea have an adverse relation with the onset of primary liver cancer(3).

Coffee is a brewed drink prepared from roasted coffee beans from the Coffee plant. According to the Japan Public Health Center-Based Prospective Study Group, regardless to hepatitis C (HCV) and B virus (HBV) infection, regular consumption may reduce the risk of liver cancer(4).In a prospective study in Japan, consisting 90,452 middle-aged and elderly Japanese subjects (43,109 men and 47,343 women) found that habitual coffee drinking may be associated with reduced risk of hepatocellular carcinoma (HCC)(5).
Dr. Petrick JL and the researchers at the The Liver Cancer Pooling Project convinced, coffee consumption is associated with reduced risk of HCC, particular in women(6).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. Its phytochemical lycopene is found to associated to liver prevention used conjunction with the formula Sho-saiko-to, the Kagawa Medical University confirmed(7).In Obese animal model, dietary lycopene can prevent (High fat diet) HFD-promoted hepatocellular carcinoma (HCC) incidence and multiplicity in mice, depending on antibody gene BCO2 expression in elicited different mechanisms(8).
Furthermore, Apo-10'-lycopenoic acid (apo-10-lycac), a metabolite of lycopene, ameliorated the HFD-promoted hepatic tumorigenesis by in stimulating the cell survival mechanism of SIRT1 gene(9).

The finding of the effectiveness of Green Tea, Coffee and Tomato may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of  Liver cancer 

People who are at increased risk of Liver cancer , due to family history, auto immunity,....should drink the juices at least one a day. People with Liver cancer  should drink the juice as much as  as they can depending to digestive toleration.
Life style and diet pattern change are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Green tea consumption and the risk of liver cancer in Japan: the Ohsaki Cohort study by Ui A1, Kuriyama S, Kakizaki M, Sone T, Nakaya N, Ohmori-Matsuda K, Hozawa A, Nishino Y, Tsuji I.(PubMed)
(2) Green tea and liver cancer risk: A meta-analysis of prospective cohort studies in Asian populations. by Huang YQ1, Lu X2, Min H1, Wu QQ1, Shi XT1, Bian KQ1, Zou XP3.(PubMed)
(3) Epidemiological studies of the association between tea drinking and primary liver cancer: a meta-analysis by Fon Sing M1, Yang WS, Gao S, Gao J, Xiang YB.(PubMed)
(4) Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status by Inoue M, Kurahashi N, Iwasaki M, Shimazu T, Tanaka Y, Mizokami M, Tsugane S; Japan Public Health Center-Based Prospective Study Group(PubMed)
(5) Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: a prospective study in Japan by Inoue M1, Yoshimi I, Sobue T, Tsugane S; JPHC Study Group(PubMed)
(6) Coffee Consumption and Risk of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Sex: TheLiver Cancer Pooling Project. by Petrick JL1, Freedman ND2, Graubard BI2, Sahasrabuddhe VV2, Lai GY3, Alavanja MC2, Beane-Freeman LE2, Boggs DA4, Buring JE5, Chan AT6, Chong DQ7,Fuchs CS8, Gapstur SM9, Gaziano JM10, Giovannucci EL11, Hollenbeck AR12, King LY6, Koshiol J2, Lee IM5, Linet MS2, Palmer JR4, Poynter JN13, Purdue MP14, Robien K15, Schairer C2, Sesso HD5, Sigurdson AJ2, Zeleniuch-Jacquotte A16, Wactawski-Wende J17, Campbell PT9, McGlynn KA2.(PubMed)
(7) Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of spontaneous liver cancer by Watanabe S1, Kitade Y, Masaki T, Nishioka M, Satoh K, Nishino H.(PubMed)
(8) Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice by Ip BC1, Liu C2, Ausman LM1, von Lintig J3, Wang XD4.(PubMed)
(9) Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice by Ip BC1, Hu KQ, Liu C, Smith DE, Obin MS, Ausman LM, Wang XD.(PubMed)

Most Common Diseases of 50plus: Pulmonary vascular disease(Respiratory disease): Pulmonary veno-occlusive disease The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing, etc,.

   Pulmonary vascular disease:  Pulmonary veno-occlusive disease 


Pulmonary vascular disease is defined as a condition of blood flow to the lung’s artery is blocked suddenly due to a blood clot somewhere in the body, including pulmonary embolism, chronic thromboembolic disease, pulmonary arterial hypertension, pulmonary veno-occlusive disease, pulmonary arteriovenous malformations, pulmonary edema, etc.

Pulmonary veno-occlusive disease (PVOD) is an extremely rare form of pulmonary hypertension, affecting mostly in children and young adults as a result of a progressive obstruction of small pulmonary veins that leads to elevation in pulmonary vascular resistance and right ventricular failure.

                             The Causes

Although the cause of Pulmonary veno-occlusive disease (PVOD) is considered unknown, some studies suggested the following
1. Oral contraceptives
According to the study by the University of California San Francisco, there ia 2 cases of PVOD that developed in 2 young women soon after the initiation of oral contraceptives (OCs). The first patient is a 14-year-old girl, with no medical history, who started taking an OC 3 weeks before the onset of symptoms. The second patient is an 18-year-old girl, diagnosed 2 years previously with systemic lupus erythematosus and lupus anticoagulant, who started taking an OC 4 months before the onset of symptoms(7).
2. Idiopathic or complicating other conditions
According to the study by the Hôpital Antoine Béclère, Assistance Publique – Hôpitaux de Paris, Université Paris-Sud, Clamart, France, PVOD has been described as idiopathic or complicating other conditions, including connective tissue diseases, HIV infection, bone marrow transplantation, sarcoidosis and pulmonary Langerhans cell granulomatosis(8).
3. Infections, Toxic Exposures, Thrombotic Diathesis, Autoimmune Disorders may also be the possible causes of PVOD
a. Infection and Toxic Exposures
No convincing data have linked PVOD to a specific infectious insult, although an “influenzalike illness” has preceded the development of PVOD in many cases, and serologic evidence suggestive of recent infection with one of several agents (including Toxoplasma gondii and measles) has been documented around the time when PVOD was diagnosed(8a). According to the study by the Service de Pneumo-Allergologie, there is a report of case of a 27 year old male intravenous drug abuser with HIV infection and pulmonary hypertension. Open lung biopsy led to the diagnosis of pulmonary veno-occlusive disease. This second case of pulmonary veno-occlusive disease raises the question of a relationship between HIV infection and lesions involving the pulmonary veins. However, the pathogenesis of vascular changes remains to be elucidated(9). Other study report a case of a Caucasian female with a long history of progressive dyspnoea ultimately diagnosed as focal granulomatous venulitis leading to a pulmonary veno-occlusive disease-like pathology(10).
b. Thrombotic Diathesis
According to the study by research team lead by Tsou E, there is a report of a 23-year-old woman in her 27th week of gestation presented with clinical findings of progressive pulmonary hypertension. After cardiac catheterization she went into labor and was delivered by cesarean section. She died shortly thereafter from right heart failure. Pulmonary venoocclusive disease was found at autopsy. Hemodynamic changes during pregnancy, labor, delivery, and the postpartum period may have contributed to her deterioration and death(11).
c. Autoimmune Disorders
There is a report of a 26-year-old woman with systemic lupus erythematosus (SLE) developed dyspnea and hypoxemia on exertion. She died from rapidly progressive respiratory failure. Autopsy revealed right ventricular hypertrophy and occlusion of the pulmonary veins compatible with pulmonary venoocclusive disease (PVOD), according to the study by Keio University School of Medicine(12).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(7) http://www.ncbi.nlm.nih.gov/pubmed/22884388
(8) http://www.ncbi.nlm.nih.gov/pubmed/19118230
(8a) http://www.atsjournals.org/doi/full/10.1164/ajrccm.162.5.9912045#h15
(9) http://www.ncbi.nlm.nih.gov/pubmed/8620974
(10) http://www.ncbi.nlm.nih.gov/pubmed/19251802
(11) http://www.ncbi.nlm.nih.gov/pubmed/6738961
(12) http://www.ncbi.nlm.nih.gov/pubmed/8014950

Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Life style modification according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia



                                                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).



                               The Treatment
B. Treatment in herbal and traditional Chinese medicine
B.1. Life style modification according herbal and TCM medicine specialist
Life style modification has shown to be beneficiary for patients with Rheumatoid Arthritis to improve musculoskeletal and bone health and reduce disability. Dr. Jones G. and the research team at the joint study lead by University of Tasmania said" Lifestyle is of considerable importance in the first two and there is emerging evidence for rheumatoid arthritis despite it not traditionally being considered a lifestyle disease"(205). Modern herbal and TCM medicine specialists may suggest the following
B.1.1. Maintain balance weight
Maintain healthy weigh is important not only for reduce cost of treatment according to the study of retrospective analysis of 66 patients from a Spanish 1,000 beds-hospital Rheumatology Clinic Service(206) but also attenuate the risk of motility in patient with rheumatoid arthritis(207).
Dr. Baker JF and the research team at the joint study lead by Philadelphia VA Medical Center and University of Pennsylvania said" . Weight loss at an annualized rate of ≥3 kg/m(2) was associated with the greatest risk of death (HR 2.49, 95% CI 1.73-3.57, P < 0.001). Low BMI (<20 kg/m(2) ) in patients with a history of obesity (>30 kg/m(2) ) was associated with the greatest risk (HR 8.52, 95% CI 4.10-17.71, P < 0.001)(208).
In fact, many scientists have concerned for the rapidly increasing prevalence of obesity may contribute to recent increase in the incidence of rheumatoid arthritis(RA)(209).

B.1.2. Exercise
Exercise, today is less popular leisure-time activity in many countries throughout the Western world, especially in the youth due to promotion of information collection through mobile phone. Exercise as medicine has been found to benefit to many forms of chronic diseases, including rheumatoid arthritis(210). Dr. Pedersen BK and Dr.Saltin B. Said" Considerable knowledge has accumulated in recent decades concerning the significance of physical activity in the treatment of a number of diseases,....... muscle, bone and joint diseases"(211).
Arobic capacity and/or muscle strength training(212), physical training exercise(213) are recommended as routine practice in patients with RA. In fact, according to the Bowman Gray School of Medicine, therapeutic exercise performance in patient with rheumatoid arthritis have shown in improving aerobic capacity, strengthening muscles, improving endurance and increasing flexibility(214).


B.1.3. Quite smoking
Smoking is a risk factor for RA,and heavy smokers, according to the Kobe University Graduate Schoolof Medicine(217)(218)
Smoking has been found to induce many forms of lung disease, and cancer,. According to statistic, smoking cause death of over 83% of patient with lung cancer. Recent study suggested of the associated of lung diseases suchas bronchiectasis and unexplained dyspnea as predictor for the future development of rheumatoid arthritis, due to inflammation induced by external triggers (such as smoking) (215).
In a total of 857 patients, for determination of the effects of cigarette smoking in RA disease severity,pack years of cigarette smoking was significantly associated with rheumatoid factor seropositivity and radiographic erosions but less severe radiographic disease seemed to be more strongly associated with cigarette smoking than more severe disease(216).

B.1.4. Reduced intake of coffee
Coffee, one of many flavor drink in many culture may be associate to risk of rheumatoid arthritis, as coffee drunk daily was found directly proportional to the prevalence of RF positivity in dose depend-manner, according to the National Public Health Institute in a cohort of 18 981 men and women who had neither arthritisnor a history of it at the baseline examination in 1973-76. Up to late 1989(218). Recent study by the University of Alabama at Birmingham also suggested that decaffeinated coffee intake is independently and positively associated with RA onset(219).
Other studies insisted of little evidence of an association between coffee, decaffeinated coffee, or tea consumption and the risk of RA among women, including the Harvard Medical School, and Brigham and Women's Hospital(220).

B.1.5. Moderate alcohol drinking
Intake of moderate alcohol has been found to induce diseases protection. According to the Brigham and Women's Hospital and Harvard Medical School, long term moderate alcohol drinking are also associate to reduce risk of RA(221) and study of 34,141 women born between 1914 and 1948, followed up from 1 January 2003 to 31 December 2009 by the Institute of Environmental Medicine(222).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References

(201) Selective JAK inhibitors in development for rheumatoid arthritis by Norman P1.(PubMed)
(202) Targeting the Janus kinases in rheumatoid arthritis: focus on tofacitinib by Yamaoka K1, Tanaka Y.(PubMed)
(203) Methotrexate and early postoperative complications in patients with rheumatoid arthritis undergoing elective orthopaedic surgery by Grennan DM1, Gray J, Loudon J, Fear S.(PubMed)
(204) 2012 Brazilian Society of Rheumatology Consensus for the treatment of rheumatoid arthritis.[Article in English, Portuguese] by da Mota LM1, Cruz BA, Brenol CV, Pereira IA, Rezende-Fronza LS, Bertolo MB, de Freitas MV, da Silva NA, Louzada-Júnior P, Giorgi RD, Lima RA, da Rocha Castelar Pinheiro G; Brazilian Society of Rheumatology.(PubMed)

(205) Lifestyle modifications to improve musculoskeletal and bone health and reduce disability--a life-course approach by Jones G1, Winzenberg TM2, Callisaya ML3, Laslett LL4.(PubMed)
(206) Cost analysis of biologic drugs in rheumatoid arthritis first line treatment after methotrexate failure according to patients' body weight.[Article in English, Spanish] by Román Ivorra JA1, Ivorra J1, Monte-Boquet E2, Canal C3, Oyagüez I4, Gómez-Barrera M5.(PubMed)
(207) Paradoxical effect of body mass index on survival in rheumatoid arthritis: role of comorbidity and systemic inflammation by Escalante A1, Haas RW, del Rincón I.(PubMed)
(208) Weight Loss, the Obesity Paradox, and the Risk of Death in Rheumatoid Arthritis. by Baker JF1, Billig E2, Michaud K3, Ibrahim S1, Caplan L4, Cannon GW5, Stokes A6, Majithia V7, Mikuls TR8.(PubMed)
(209) Contribution of obesity to the rise in incidence of rheumatoid arthritis by Crowson CS1, Matteson EL, Davis JM 3rd, Gabriel SE.(PubMed)
(210) Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases by Pedersen BK1, Saltin B2.(PubMed)
(211) Evidence for prescribing exercise as therapy in chronic disease by Pedersen BK1, Saltin B.(PubMed)
(212) Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis by Hurkmans E1, van der Giesen FJ, Vliet Vlieland TP, Schoones J, Van den Ende EC.(PubMed)




(213) Effects of a group-based exercise and educational program on physical performance and disease self-management in rheumatoid arthritis: a randomized controlled study by Breedland I1, van Scheppingen C, Leijsma M, Verheij-Jansen NP, van Weert E.(PubMed)
(214) Therapeutic exercise for rheumatoid arthritis and osteoarthritis by Semble EL1, Loeser RF, Wise CM.(PubMed)
(215) The lung in rheumatoid arthritis, cause or consequence? by Chatzidionisyou A1, Catrina AI.(PubMed)
(216) Cigarette smoking and rheumatoid arthritis severity by Saag KG1, Cerhan JR, Kolluri S, Ohashi K, Hunninghake GW, Schwartz DA.(PubMed)
(217) Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies by Sugiyama D1, Nishimura K, Tamaki K, Tsuji G, Nakazawa T, Morinobu A, Ku) .(PubMed)
(218) Coffee consumption, rheumatoid factor, and the risk of rheumatoid arthritis. by Heliövaara M1, Aho K, Knekt P, Impivaara O, Reunanen A, Aromaa A.magai S(PubMed)
(219) Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study by Mikuls TR1, Cerhan JR, Criswell LA, Merlino L, Mudano AS, Burma M, Folsom AR, Saag KG.(PubMed)
(220) Coffee consumption and risk of rheumatoid arthritis by Karlson EW1, Mandl LA, Aweh GN, Grodstein F.(PubMed)
(221) Alcohol consumption and risk of incident rheumatoid arthritis in women: a prospective study. by Lu B1, Solomon DH, Costenbader KH, Karlson EW.(PubMed)
(222) Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study by Di Giuseppe D1, Alfredsson L, Bottai M, Askling J, Wolk A.(PubMed)

The Smoothie of Sweet Potato, Peony and Licorice for Reduced Risk and Treatment of Galactorrhea

 Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Galactorrhea
Yield: 2 servings (about 8 ounces each)
1 1/2  cup cooked sweet potato
1/2 cup Peony herbal tea drink (make from one tea bag about 2 gram)
1/2 cup Licorice herbal tea drink(make from one tea bag about 2 gram)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Galactorrhea is an excessive or inappropriate production of milk not related to to the normal milk production of breast-feeding.

The finding the natural ingredients for treatment of Galactorrhea is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine to other organs in the body.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Recent reports from numbers of well known institutions insisted, intake of vitamin B6(1), may be the next generation ingredient to be used on prevention and treatment of Galactorrhea(1).
Vitamin B6 is water soluble and a member of vitamin B complex, found abundantly in sweet potato, played an important role in amino acids metabolism for to maintaining the proper function in our body. According to Dr. McIntosh EN., vitamin B6 at doses of 200-600 mg/day effectively decreased the excessive secretion of prolactina(1).
Also in women with galactorrhea-amenorrhea syndromes, the vitamin exhibited acute effect on serum GH and PRL levels, through suppressing galactorrhea and restoring normal menses(2).

Shao Yao Gan Cao Tang (Shakuyaku-kanzo-to), a traditional Chinese medicine formula containing
Peony and Licorice, in Randomized, Open-Label Study showed to improve complication of  olanzapine-associated hyperprolactinemia(3), attenuated neuroleptic-induced hyperprolactinemia(4).
According to Dr. Yamada K and colleagues at the Keio University, School of Medicine, intake of Shakuyaku-kanzo-to (TJ-68) reduced the mean plasma prolactin level decreased significantly from 28.9 +/- 14.5 ng/mL at baseline to 22.0 +/- 15.2 ng/mL at 4 weeks(5).

The Smoothie of Sweet Potato, Peony and Licorice may hold a key for further studies in production of curable natural remedy in reduced risk and treatment of Galactorrhea.

Women who are at increased risk of Galactorrhea due to family history, ... should drink at least one cup or more daily and women with Galactorrhea should drink as much as they can, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

References
(1) Treatment of women with the galactorrhea-amenorrhea syndrome with pyridoxine (vitamin B6).by McIntosh EN.(PubMed)
(2) Ineffectiveness of pyridoxine (B6) to alter secretion of growth hormone and prolactin and absence of therapeutic effects on galactorrhea-amenorrhea syndromes by Tolis G, Laliberté R, Guyda H, Naftolin F.(PubMed)
(3) Herbal medicine (Shakuyaku-kanzo-to) improves olanzapine-associated hyperprolactinemia: a case report by Hori H, Yoshimura R, Katsuki A, Nakamura J.(PubMed)
(4) Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia by Yamada K, Kanba S, Yagi G, Asai M.(PubMed)
(5) Effectiveness of shakuyaku-kanzo-to in neuroleptic-induced hyperprolactinemia: a preliminary report by Yamada K1, Kanba S, Murata T, Fukuzawa M, Terashi B, Yagi G, Asai M.(PubMed)