Medical Advisor Journals

Monday, May 23, 2016

Most common Diseases of 50plus: The Obesity' Research and Studies - Obesity, growth hormone and weight loss

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) "Obesity, growth hormone and weight loss." by Rasmussen MH. (Department of Endocrinology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark. mhr@dadlnet.dk), US National Library of Medicine National Institutes of Health

Most common Diseases of 50plus: Obesity and Obesity's complication of Chronic Venus Insufficiency

How Obesity associates with Chronic Venus Insufficiency
1. In the examination of 36 limbs in 23 nonobese individuals and 44 limbs in 22 obese individuals of the study of "Impact of obesity on venous hemodynamics of the lower limbs" by Willenberg T, Schumacher A, Amann-Vesti B, Jacomella V, Thalhammer C, Diehm N, Baumgartner I, Husmann M., posted in PubMed, researchers filed the conclusion that Lower limb venous flow parameters differ significantly between healthy obese and nonobese individuals. These findings support the mechanical role of abdominal adipose tissue potentially leading to elevated risk for both venous thromboembolism and chronic venous insufficiency.

2. According to the study of "Obesity and impaired venous function" by van Rij AM, De Alwis CS, Jiang P, Christie RA, Hill GB, Dutton SJ, Thomson IA., posted inPubMed, researchers found that The CEAP clinical stage of venous disease is more advanced in obese patients than non-obese patients with comparable anatomical patterns of venous incompetence. This may be the result of raised intra-abdominal pressure reported in previous studies, leading to greater reflux, increased vein diameter and venous pressures.

3. In the study of "Clinical presentation and patterns of venous reflux in Thai patients with chronic venous insufficiency (CVI)" by Kanchanabat B, Wongmahisorn Y, Stapanavatr W, Kanchanasuttirak P, Manomaiphiboon A., posted in PubMed, the group found that Thai patients with CVI were relatively young. Visible varicose veins, pain, oedema and inflammation were uncommon and most patients could maintain their usual activities despite advanced venousdisease. An association with obesity was not common. Despite a low prevalence of a history of previous DVT, the prevalence of deep vein reflux was high and commonly combined with superficial venous reflux.

4. In the observation of 40,095 individuals from 803 registers of primary care in Poland of the study of "The influence of environmental factors in chronicvenous insufficiency" by

Jawien A., posted in PubMed, Jawien A. indicated that in the other developed countries was reported. It was more common in women, but female sex was not found to be a strong risk factor. Among the risk factors most closely associated with CVI were age, family history of varicose veins, and constipation, whatever the sex. This is in keeping with findings from recent epidemiologic studies. Obesity and lack of physical activity were strongly associated with CVI in women, more so than in men.

5. According to the study of "[Influence of environmental risk factors on the development of chronic vein insufficiency]" [Article in Polish] by Sudoł-Szopińska I, Błachowiak K, Koziński P., posted in PubMed, researchers wrote that this paper presents basic information on CVI epidemiology, etiopathogenesis and pathophysiology and also reviews the literature on the following CVI risk factors:obesity, lack of physical activity, dietary habits, including constipation, pregnancy, genetic factors as well as prolonged sedentary or upright position during job performance.

6. Etc.

Treatments of Obesity and Chronic Venus Insufficiency
1. According to the study of "In situ hemodynamics of perforating veins inchronic venous insufficiency" by Delis KT, Husmann M, Kalodiki E, Wolfe JH, Nicolaides AN., posted in PubMed, researchers found that In addition to an increase in diameter, perforator incompetence is characterized by significantly higher mean and peak flow velocities, volume flow, and venous volume displaced outward, and a lower flow pulsatility. Differences in early reflux enable a better hemodynamic stratification of incompetent perforators in CVI classes. In the presence of deep reflux, incompetent perforators sustain further hemodynamic impairment. In situ hemodynamics enable quantification of the function of perforators and can be used in the identification of the clinically relevant perforators and the impact of surgery.

2. In the study of "Effect of external valvuloplasty of the deep vein in the treatment of chronic venous insufficiency of the lower extremity" by Wang SM, Hu ZJ, Li SQ, Huang XL, Ye CS., posted in PubMed, researchers concluded that External valvuloplasty of the femoral vein combined with surgical repair of the superficial venous system improved the hemodynamic status of the lower limbs, restored valvular function more effectively, and achieved better outcomes than surgical repair of the superficial venous system alone.

3. Etc.

Sunday, May 22, 2016

Most Common Disease of 50plus: Hypertension- The Effect of Diet on High Blood Pressure

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising pressure in your heart and staying high over time, damaging the body in many ways. High blood pressure or arterial hypertension is almost never a serious health threat. However, doctors attempt to lower it in their patients because it can have serious long-term consequences. Since general approaches and supplements have provided us with many clues in controlling high blood pressure. We can control it with natural foods.

1. Celery
If you are asking advice from your doctor about high blood pressure, chances are he will tell you to take 4 stalks of celery daily. Study shows that celery contains a chemical called limonene that acts as a mild tranquilizer that can lower levels of stress hormones in your blood. This allows your blood vessels to expand, giving your blood more room and reducing pressure.

2. Red tea
Red tea has flavonoids, which have been proven effective in treating assorted skin and circulation problems.

3.Fresh water algae or dark green vegetable
Fresh water algae contains a high amount of chlorophyll. Study shows that regular use of chlorella reduces high blood pressure and prevents strokes. When chlorella has been used consistently over a period of months, the low pressure often increases to normal.

4. Avocado
Avocados are a good source of potassium, a mineral that helps regulate blood pressure. Adequate intake of potassium can help to guard against circulatory diseases like heart disease or stroke.

5. Whole grain
Whole grains which provide all edible parts of the grain include whole-grain corn, oats, popcorn, brown rice, whole rye, etc. Study shows that eating just one daily serving of whole grains may help prevent high blood pressure - and more servings could slash your risk even further.

6. Cold water fish
Cold-water fish like wild Alaskan salmon and sardines which are rich in omega-3 fatty acids that has been proven record of lowering cholesterol levels and increasing blood circulation in your body, and subsequently reducing high blood pressure. Take fish-oil supplements if you cannot get enough omega-3-rich foods.

7. Gracefruit and beet juice
The effect was traced to nitrate in the gracefruit and beet juice that reacted with bacteria in the mouth. This led to chemical changes which resulted in blood vessels dilating to increase blood flow and reducing blood pressure.
Foods help to control high blood pressure also have the function of lowering cholesterol level as well as increase circulation of blood in the body, therefore it reduces the risk of heart disease and stroke.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Most Common Disease of 50plus: High Blood Cholesterol - Cholesterol Level and Nutritional Supplements

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cholesterol level is controllable through intake of healthy foods because healthy foods contain high levels of HDL that help to remove LDL from blood to the liver where it is eliminated. In this article, we will provide the information of how nutritional supplements help in lowering cholesterol.
Nutritional supplements place an important role in lowering cholesterol levels for cost effectiveness and little side effects compared to prescription medications.

Some of the below nutritional supplements have proven record of lowering cholesterol levels:
1. Vitamin C
Vitamin C is a water soluble vitamin, which means it isn't stored by your body. That makes it even more important to get as much as you need on a daily basic. Vitamin C contains antioxidants that reduce heart attack risk by blocking chemical changes that causes LDL cholesterol to stick to arterial walls and subsequently lowering cholesterol levels.

2. Vitamin E
Vitamin E is a fat-soluble vitamin which may not help to lower cholesterol levels, but it can help to prevent LDL cholesterol from becoming oxidized and sticking to your artery walls in result of lowering cholesterol levels. Be sure to talk to your doctor if you are taking any blood thinning medications.

3. Niacin
Niacin is one of the water-soluble B vitamins. Niacin lowers the bad LDL cholesterol and triglyceride levels while raising the good HDL cholesterol level. People taking niacin to lower serum cholesterol should be closely monitored by their doctor to avoid complications.

4. Magnesium
Magnesium deficiency increases the danger of heart disease and stroke as we mentioned in the previous article. Study shows that adding this mineral to your diet could lower your cholesterol level by 33%.

5. Green tea extract
Green tea extract counters the effect of radication, keeps the pH of blood balanced and is high in antioxidants. Green teas that contain polyphenolic catechins are actually stronger than vitamin E. This helps to prevent LDL cholesterol from becoming oxidized and sticking to your artery walls in result of lowering cholesterol levels.

6. Lutein
Study shows that people that have alot of lutein in their blood stream see no increase in the thickness of their carotid arteries. That means LDL cholesterol have not oxidized causing formation of dangerous plaque at their arteries wall leading to heart attacks and lowering cholesterol levels.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Food Therapy: Miso

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Miso is a traditional Japanese seasoning produced by fermenting rice, barley andsoybeans, with salt and the fungus. Depending to the time required for fermentation, it is classified into difference types of miso. Since it contains high amount of in protein, vitamins and minerals, it now becomes increasingly popular in the West.

Nutrients
1. Protein
2. Omega 3 fatty acid
3. Thiamin
4. Niacin
5. Vitamin K
6. Calcium
7. Copper
8. Iron
9. Manganese
10. Zinc
11. Etc

Health Benefits
A. Health benefits according to Studies
1. Type II diabetes
In the valuation of the association between soy products and their components and theirs effect in type II diabetes found that the current findings support a protective role for unsweetened soy foods and isoflavones on risk of type 2 diabetes, according to "Soy intake and risk of type 2 diabetes mellitus in Chinese Singaporeans : Soy intake and risk of type 2 diabetes" by Mueller NT, Odegaard AO, Gross MD, Koh WP, Yu MC, Yuan JM, Pereira MA.(a)

2. Obesity
In the investigation of a Fermented Soybean Paste and its anti obese effect found that fermented soybean product, was more effective than soybeans for preventing diet-induced visceral fat accumulation, possibly because of its greater effects on CPT-1 activity stimulation and FAS activity suppression. These effects may be due in part to the higher content of aglycone isoflavones in doenjang, according to "Doenjang, a Fermented Soybean Paste, Decreased Visceral Fat Accumulation and Adipocyte Size in Rats Fed with High Fat Diet More Effectively than Nonfermented Soybeans" by Kwak CS, Park SC, Song KY.(b)

3. Breast cancer
In the observation of high concentration of isoflavones and peptides of fermentedsoybeanand theirs effect in breast cancer wrote that based on the experimental results, taking fermented soybean might be helpful for preventing breast cancer by a mechanism activating TGFβ pathway and depressing inflammation, according to "Inflammation-related signaling pathways implicating TGFβ are revealed in the expression profiling of MCF7 cell treated with fermented soybean, chungkookjang" by Hwang JS, Yoo HJ, Song HJ, Kim KK, Chun YJ, Matsui T, Kim HB.(c)

4. Antioxidant activity
In the assessment of a Chinese traditional fermented product of soybean and its antioxidant effect found that taking into account of extraction yields, the sufu product ripened at 45°C for 16 days showed the most profound enhancement in the DPPH radical-scavenging effect and Fe(2+)-iron-chelating ability, which is 3.4 and 11.5 folds, respectively, that noted with the non-fermented tofu, according to "Fermentation temperature affects the antioxidant activity of the enzyme-ripened sufu, an oriental traditional fermented product of soybean" by Huang YH, Lai YJ, Chou CC.(d)

5. Iron deficiency anemia
In the examination of fermented soybean and it effect in Iron deficiency anemia of cjildren found that The iron absorption rate (21.8%) in the children given the diet containing fermented soy was significantly higher than that of (14.2%) in the children given the bland diet (control group) and about the same as that in the FeSO4 group (22.48%) 58Fe, according to "[A study on the effect of fermentedsoybean in preventing iron deficiency anemia in children][Article in Chinese] by Qin HS.(e)

6. Etc.

B. Health benefits according to concentration
1. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(1)

2. Manganese
Manganese beside plays an vital role for the proper and normal growth of human bone structure (accodring to the study of "Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants" by Pabbruwe MB,Standard OC, Sorrell CC, Howlett CR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15109850)), it also helps to reduce the risk of cancer, (according to the study of "The effects of 3, 4 or 5 amino salicylic acids onmanganese-induced neuronal death: ER stress and mitochondrial complexes" by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

3. Vitamin K
Vitamin K not only plays an important role in protecting our skin from aging, it is also needed for the proper clotting of blood, thus decreasing the risk of excessive bleeding, in a study of "Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!" by Kasatkar P, Shetty S, Ghosh K., posted inPubMed, researchers found that Laboratory tests confirmed acquired bleeding diathesis due to vitamin K deficiency, which was corrected after adequate vitamin K supplementation. VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis.

4. Protein
In the evaluation of soy protein diet abd it effects on serum creatinine, found thatsoy feeding was associated with higher renal and hepatic linoleic acid content and higher hepatic alpha-linolenic acid, but lower hepatic arachidonic acid content. and concluded that Isocaloric soy protein feeding ameliorates both epithelial and interstitial changes in the Han:SPRD-cy rat independent of a hypocholesterolemic effect. The histologic benefit is associated with changes in polyunsaturated fatty acid metabolism that may influence both inflammatory and proliferative pathways, according to the study of "Modification of polycystic kidney disease and fatty acid status by soy protein diet" by Ogborn MR, Nitschmann E, Weiler HA, Bankovic-Calic N.(4)

5. Etc.

C. Other health benefits
1. Antiging
Vitamin K beside is essential to the coagulation of blood by stopping the skin from bleeding after wound or cut, it also helps to protect the under layer of the skin against leaking due to aging, depending to the level of vitamin K-dependent coagulation factors, according to the study of "The pharmacology of oral anticoagulants: implications for therapy" Shetty HG, Woods F, Routledge PA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/8269110), researchers indicated that a number of factors such as altered absorption, distribution, elimination, genetic factors, aging, vitamin K excess or deficiency, alterations in the level of vitamin K-dependent coagulation factors and drug interactions may affect response to oral anticoagulants. Adverse effects include hemorrhage, skin necrosis and teratogenicity. Phenindione can also cause serious hypersensitivity reactions.

2. Omega 3 fatty acid
Beside is important to reduce the over reaction of the abdominal muscle by balancing the ratio of omega 3 and 6 fatty acid, omega 3 fatty acid also helps to increase the good cholesterol HDL in the blood stream, thus reducing the risk of hypertension causes of heart diseases., according to the study of "Effects ofOmega-3 Fatty Acids on Serum Lipids, Lipoprotein (a), and Hematologic Factors in Hemodialysis Patients" by Kooshki A, Taleban FA, Tabibi H, Hedayati M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21859401)

3. Bone heath
Magnesium beside plays an important in stabilizing the heart rhythm and prevents the abnormal blood clotting in the heart ( according to the study of "Dietarymagnesium deficiency induces heart rhythm changes, impairs glucose tolerance, and decreases serum cholesterol in post menopausal women" by Nielsen FH, Milne DB, Klevay LM, Gallagher S, Johnson L., posted in OubMed, (http://www.ncbi.nlm.nih.gov/pubmed/17536123)), it also helps to maintain the ratio of calcium, thus enhancing the body in calcium absorption in building healthy bone (according to the study of "A moderately high intake compared to a low intake of zinc depresses magnesium balance and alters indices of bone turnover in postmenopausal women" by Nielsen FH, Milne DB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15116072)).

4. Protein
Protein beside is important building block of bones, muscles, cartilage, skin, and blood, it also enhances the nervous system in information transmitting between cells and cells of the other parts of the body, thus reducing the risk of nervous tension, (according to the study of "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function" by
Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N, posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20660256)

5. Iron
Iron, the trace minerals, is not only important to reduce the implication of oxidative stress and cardiovascular health (according to the study of "[Iron deficiency and overload. Implications in oxidative stress and cardiovascular health].[Article in Spanish]" by Toxqui L, De Piero A, Courtois V, Bastida S, Sánchez-Muniz FJ,Vaquero MP., posted in PubMed, (http://www.ncbi.nlm.nih.gov/pubmed/20593115) it also helps in production of red blood cells and formation of hemoglobin which enhances the absorption oxygen from the lung to nourish the cells in the body.

6. Reproductive health
Zinc is essential for the health prostate gland. Deficiency of zinc not only causes prostate enlargement, but also decreases the prostate function in production of semen and increases the risk of abnormal sperm production. In a study of "Disturbed homeostasis of zinc and other essential elements in the prostate glanddependent on the character of pathological lesions" by
Sapota A, Darago A, Taczalski J, Kilanowicz A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19629715), researchers found that The results apparently confirm the disturbed homeostasis of zinc and other essential elements in the etiology of BPH and PCa.
7. Etc.

Side effect
1. It contain a measure amount of sodium but you can choose with less
2. Since it has soybean as an ingredient, it may cause allergic effect.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22094581
(b) http://www.ncbi.nlm.nih.gov/pubmed/22082067
(c) http://www.ncbi.nlm.nih.gov/pubmed/21547849
(d) http://www.ncbi.nlm.nih.gov/pubmed/21497549
(e) http://www.ncbi.nlm.nih.gov/pubmed/2627849
(1) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(2) http://www.millipore.com/references/tech1/7yv3hk

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Cause

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

Polymyalgia Arthritis (Rheumatica)

Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

The causes

The cause of PMR is not well understood, but researchers believe it is a result of the abnormal inflammatory activity of inflammatory cells and proteins of the immune system due to the presence of a synovitis in proximal joints and periarticular structures, causes by the following

1. Influenza B infectionNumber of infectious agents have been found to induce the cause of polymyalagia rheumatica(PMR) associated to human leukocyte antigens (HLAs), such as HLA-DRB1 and HLA-DQB(10). According to the Kobe University Hospital, contracting influenza virus B is also found to influence to the development of PMR(9). Dr. Peris P said," Onset of symptoms in PMR is unrelated to seasonal pattern. Yet almost 50% of cases occurred in the months of May, February, and August"(12) and there is no association between infection and onset of polymyalgia rheumatica(13), the Ciudad Sanitaria y Universitaria de Bellvitge argued.

2. Genetic factors
In the study to evaluate HLA-DRB1 associations in patients with polymyalgi arheumatica (PMR), acording to the study based HLA-DRB1 genotyping in 89 PMR patients, 44 GCA patients, and 99 unrelated healthy controls from the same geographic area(10). Dr Pease CT and the research team at the University of Leeds, in the diagnosed of musculoskeletal disorder said, "the presence of HLA-DRB1*04 may indicate underlying RA or TA."(11)

3. Environmental factors
Environmental contagious factors have been found to link to the onset of at least 1/4 percent of the patient with PMR, according to the study of 460 patients (128 with isolated PMR, 227 with isolated GCA, 105 with PMR/CGA), by the Dupuytren University Hospital, Limoges(14).

According to the database of the World Health Organisation (WHO), statin, the prescribed medication for lowering blood cholesterol levels, using Anatomical Therapeutic Chemical (ATC) classification, may be may be associated with the occurrence of PMR(15).

Some researchers including Goëb V also concerned the risk of Cerivastatin-induced PMR(16) and patient reexposure to a statin is also associated to the developed polymyalgia rheumatica(17).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(9) HLA-DRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis by Martínez-Taboda VM1, Bartolome MJ, Lopez-Hoyos M, Blanco R, Mata C, Calvo J, Corrales A, Rodriguez-Valverde V.(PubMed)
(10) HLA-DRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis by Martínez-Taboda VM1, Bartolome MJ, Lopez-Hoyos M, Blanco R, Mata C, Calvo J, Corrales A, Rodriguez-Valverde V.(PubMed)
(11) Diagnosing late onset rheumatoid arthritis, polymyalgia rheumatica, and temporal arteritis in patients presenting with polymyalgic symptoms. A prospective longterm evaluation by Pease CT1, Haugeberg G, Morgan AW, Montague B, Hensor EM, Bhakta BB.(PubMed)
(12) Polymyalgia rheumatica is not seasonal in pattern and is unrelated to parvovirus b19 infection by Peris P1.(PubMed)
(13) Lack of association between infection and onset of polymyalgia rheumatica by Narváez J1, Clavaguera MT, Nolla-Solé JM, Valverde-Garcia J, Roig-Escofet D.(PubMed)
(14) Familial aggregation in giant cell arteritis and polymyalgia rheumatica: a comprehensive literature review including 4 new families by Liozon E1, Ouattara B, Rhaiem K, Ly K, Bezanahary H, Loustaud V, Letellier P, Drouet M, Vidal E.(PubMed)
(15) Statin-associated polymyalgia rheumatica. An analysis using WHO global individual case safety database: a case/non-case approach by de Jong HJ1, Saldi SR, Klungel OH, Vandebriel RJ, Souverein PC, Meyboom RH, Passier JL, van Loveren H, Cohen Tervaert JW.(PubMed)
(16) Cerivastatin-induced polymyalgia rheumatica-like illness by Goëb V, Guillemant N, Vittecoq O, Le Loët X.(PubMed)
(17) Giant cell arteritis and polymyalgia rheumatica after reexposure to a statin: a case report by de Jong HJ, Meyboom RH, Helle MJ, Klungel OH, Niskanen L, Cohen Tervaert JW.(PubMed)

The Delicious Smoothie of Cooked Sweet Potato, Olive and Grape Juice for Complication Prevention and Treatment of Chronic Kidney Diseases(CKD)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post

Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Chronic Kidney Diseases(CKD)

Yield: 2 servings (about 8 ounces each)

1/2 cup olive
1 cup cooked sweet potato
1 cup organic grape juice

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Chronic Kidney Diseases(CKD) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Cooked Sweet Potato, Olive and Grape Juice may be the next generation of natural ingredients for prevention and treatment of Chronic Kidney Diseases(CKD).

Chronic Kidney Diseases(CKD) is a progressive loss of kidney function over period longer than 3 months through different stages, deepening to the GFR (Glomerular Filtration Rate). According to the Tri-Service General Hospital, Excessive oxidative stress increased oxidative nucleicacid damage and exagerated the development of complication of Chronic Kidney Diseases(1).

The Anti-Odxidant Therapy in Chronic Renal Insufficiency (ATIC) study suggested, combination of pravastatin, vitamin E, and homocysteine treatment in 18 months together with hypertension controlled effectively attenuated expression of Chronic Kidney Diseases(CKD) through reduced oxidative stress against renal function(2).Vitamin E-coated membranes (VECMs) consist of a multilayer membrane with liposoluble vitamin E, used in dialysis significantly improved Hb levels and lower rHuEpo requirements in chronic HD patients(3).Dr. Rashid Khan M and colleagues insisted, vitamin E significantly reduced dyslipidemia and inhibited the development of CRD caused by atherogenic factors after six weeks. particular in hypolipidemic and nephroprotective activity against free radical-related diseases(4).

N-3 fatty acids found abundantly in olive may also contribute to the potential benefits of dietary fat
modification in CKD patients, according to the Karolinska Institutet(5).
Dr. Lee SM and Dr. An WS., professors at the Seoul National University Hospital, insisted, intake of Omega 3 fatty acid exhibited cardioprotective effects in chronic kidney disease, the main cause of death, through attenuated inflammation, dyslipidemia, malnutrition, atherosclerosis, and vascular calcification(6).
Dr. Friedman AN said, " Long-chain polyunsaturated omega-3 fatty acids (n-3 PUFA), which are obtained primarily from dietary sources such as coldwater fish, have diverse and potent mediating effects on the immune, inflammatory, and metabolic pathways, signal transduction, and cell membrane physiology" and "In the meantime, the current American Heart Association n-3 PUFA intake guidelines can be applied to CKD patients"(7).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry, may also benefit in attenuated complications and treatment of Chronic Kidney Diseases(CKD), through its inflammation and oxidative stress modulation (8).
According to the joint study led by the The Catholic University of Korea, Bucheon, resveratrol expressed renoprotective effects by activating NRF2 signaling against against oxidative or electrophilic stress(9).Furthermore by suppressing the pro inflammatory cytokines, consumption of white wine and olive oil, significantly reduced plasma markers of chronic inflammation in CKD patients(10).

The effectiveness of Cooked Sweet Potato, Olive and Grape Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Albuminuria with little or no adverse effects.

People who are at high risk of Chronic Kidney Diseases(CKD) due to aging, weaken reno function... should drink at least one serving daily and People with Chronic Kidney Diseases(CKD) should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary.

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References
(1) Oxidative stress and nucleic acid oxidation in patients with chronic kidney disease by Sung CC1, Hsu YC, Chen CC, Lin YF, Wu CC.(PubMed)
(2) Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study by Nanayakkara PW1, van Guldener C, ter Wee PM, Scheffer PG, van Ittersum FJ, Twisk JW, Teerlink T, van Dorp W, Stehouwer CD.(PubMed)
(3) Effect of vitamin E-coated dialysis membranes on anemia in patients with chronic kidney disease: an Italian multicenter study by Cruz DN1, De Cal M, Garzotto F, Brendolan A, Nalesso D, Corradi V, Ronco C.(PubMed)
(4) Tocotrienols have a nephroprotective action against lipid-induced chronic renal dysfunction in rats by Rashid Khan M1, Ahsan H, Siddiqui S, Siddiqui WA.(PubMed)
(5) Dietary fat modification in patients with chronic kidney disease: n-3 fatty acids and beyond by Huang X1, Lindholm B, Stenvinkel P, Carrero JJ.(PubMed)
(6) Cardioprotective effects of ω -3 PUFAs in chronic kidney disease. by Lee SM1, An WS.(PubMed)
(7) Omega-3 fatty acid supplementation in advanced kidney disease by Friedman AN1.(PubMed)
(8) Resveratrol: why is it a promising therapy for chronic kidney disease patients?by Saldanha JF1, Leal Vde O2, Stenvinkel P3, Carraro-Eduardo JC4, Mafra D1.(PubMed)
(9) Effect of redox modulating NRF2 activators on chronic kidney disease.by Choi BH1, Kang KS2, Kwak MK3.(PubMed)