The Delicious Green Tea and Tomato for Prevention and Treatment of Lichen planus(LP)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Lichen planus
Yield: 2 serving (about 8 ounce each)
1 1/2 cup tomato
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Lichen planus has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Lichen planus is a chronic inflammatory skin condition affecting skin and/or mucosal surfaces. The skin disease causes of lacy white patches and painful sores may be related to an allergic or immune over reaction. According to the Shahid Beheshti University of Medical Sciences, patients with lichen planus are associated to lower levels of vitamin C and high levels of free radicals induced oxidative damage(1). In fact, increased oxidative stress and imbalance in the antioxidant defense mechanisms in LP showed to play an essential role in the pathogenesis of LP(2)

Recent studies back by renowned institutions, conveyed that green tea(3) may be holding a key for extracting natural ingredient for reduced early onset and treatment of Lichen planus(LP).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. In the study of the effects of plant extracts/polyphenols on oral health, polyphenols (stilbenes, flavonoids and proanthocyanidins) found abundantly in green tea and berry may be the most effective in against oral chronic degenerative and inflammatory diseases(3)., including lichen planus(LP).

According Dr. Zhang J. and Dr. Zhou G. green tea ameliorated Oral lichen planus (OLP) through regulated on activation, normal T-cell expressed, and secreted of RANTES (CCL5) chemokine as well as signaling involved in the pathogenesis of OLP(4).

Lycopene, found in tomato also exhibited anti lichen planus in the prevention of various oral diseases, according to the Swami Devi Dyal Hospital and Dental College(5).
In a prospective, randomized, double-blind, placebo-controlled study, lycopene exhibited (84%) reduction in burning sensation than in the placebo group (67%), attenuated oxidative stress in the management of oral lichen planus(6).

The finding of the effectiveness of Green Tea, Tomato may serve as cornerstones of pharmaceutical target for further studies as well as a potential medication for treatment of  Lichen planus(LP).

People who are at increased risk of  Lichen planus(LP), due to family history, auto immunity,....should drink the juices at least one a day. People with  Lichen planus(LP) should drink the juice as much as  as they can depending to digestive toleration.

Life style and diet pattern change are recommended.

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References

(1) Antioxidant status in patients with lichen planus by Barikbin B1, Yousefi M, Rahimi H, Hedayati M, Razavi SM, Lotfi S.(PubMed)
(2) Alterations in Lipid Metabolism and Antioxidant Status in Lichen Planus by Panchal FH1, Ray S2, Munshi RP1, Bhalerao SS1, Nayak CS2.(PubMed)
(3) Plant polyphenols and oral health: old phytochemicals for new fields by Varoni EM1, Lodi G, Sardella A, Carrassi A, Iriti M.(PubMed)

(4) Green tea consumption: an alternative approach to managing oral lichen planus by Zhang J1, Zhou G.(PubMed)
(5) Role of Lycopene in Preventing Oral Diseases as a Nonsurgical Aid of Treatment by Gupta S1, Jawanda MK2, Arora V3, Mehta N4, Yadav V5.(PubMed)
(6) Lycopene in the management of oral lichen planus: a placebo-controlled study by Saawarn N1, Shashikanth MC, Saawarn S, Jirge V, Chaitanya NC, Pinakapani R.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Benign lung tumors - The Diet

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).

                Diet to prevent benign lung tumors

1. Mediterranean diet
Mediterranean diet and more specifically certain meats, fruits, vegetables, and olive oil found in certain parts of the Mediterranean region have been associated with a decreased cardiovascular and diabetes risk. According to the study by University of Illinois at Chicago, showed that one agent in particular, carnosol, has been evaluated for anti-cancer property in prostate, breast, skin, leukemia, and colon cancer with promising results. These studies have provided evidence that carnosol targets multiple deregulated pathways associated with inflammation and cancer that include nuclear factor kappa B (NFκB), apoptotic related proteins, phosphatidylinositol-3-kinase (PI3 K)/Akt, androgen and estrogen receptors, as well as molecular targets(19).
2. White cabbage, green pepper, strawberry, olive, mangoes and grapes
Lupeol, found in white cabbage, green pepper, strawberry, olive, mangoes and grapes was reported to possess beneficial effects as a therapeutic and preventive agent for a range of disorders. Last 15 years have seen tremendous efforts by researchers worldwide to develop this wonderful molecule for its clinical use for the treatment of variety of disorders. These studies also provide insight into the mechanism of action of Lupeol and suggest that it is a multi-target agent with immense anti-inflammatory potential targeting key molecular pathways which involve nuclear factor kappa B (NFkappaB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/beta-catenin in a variety of cells(20).

3. Apple peel
Flavonoids and triterpenes are two major groups of bioactive compounds in apple peels. According to the study by the Betulin Institut, the antitumour effects were subsequently confirmed in a series of cancer cell lines from other origins, for example breast, colon, lung and neuroblastoma. In addition, in the last decade many studies have shown further effects that justify the expectation that triterpenes are useful to treat cancer by several modes of action. Thus, triterpene acids are known mainly for their antiangiogenic effects as well as their differentiation inducing effects. In particular, lupane-type triterpenes, such as betulin, betulinic acid and lupeol, display anti-inflammatory activities which often accompany immune modulation. Triterpene acids as well as triterpene monoalcohols and diols also show an antioxidative potential, (21).

4. Cruciferous vegetables, soybean, garlic, tomato, rice, beans, and potatoes
Phytoalexins have been identified in at least 75 plants including cruciferous vegetables, soybean, garlic, tomato, rice, beans, and potatoes suggesting plants may be a rich source of cancer-fighting compounds. According to the study by The University of Arizona,
Preclinical evidence suggests these compounds possess anticancer properties including an inhibition of microbial activity, cell proliferation, invasion and metastasis, hormonal stimulation, and stimulatory effects on expression of metabolizing enzymes(22a).


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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(19) http://www.ncbi.nlm.nih.gov/pubmed/21382660
(20) http://www.ncbi.nlm.nih.gov/pubmed/19464787
(21) http://www.ncbi.nlm.nih.gov/pubmed/19742422
(22) http://www.ncbi.nlm.nih.gov/pubmed/22888839
(22a) http://www.ncbi.nlm.nih.gov/pubmed/22652763

Most common Diseases of 50plus: Heart Disease(The Articles) - The Nutritional Supplements

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                  Heart Disease

Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. There are many causes of heart disease. Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.


Heart Diseases and Nutritional Supplements


Heart diseases are caused by high blood pressure that contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. Beside foods and herbs, nutritional supplements also play an important role in preventing heart diseases and stroke.

1. L-Arginine
L-Arginine helps to increase the production of nitric oxide in our body, this has an anti-angina and anti-stress effect upon the arteries enabling the muscles in the arterial walls to relax. L-Arginine also helps to prevent the build up of plaque on the arterial walls. L- Arginne taken either orally or intravenously has been found to prevent and reverse atherosclerosis, improving the functional status of heart failure and increasing blood flow in heart disease patients.

2. L- Carnitine
L-Carnitine working with vitamin E will help the body to recover quickly from fatigue. L-Carnitine helps the body convert fatty acids into energy, which is used primarily for muscular activities throughout the body. When working with vitamin E, L-carnitine will help the body to recover quickly from fatigue and combat heart diseases.

3. Lecithin
Lecithin supplies the body with needed inositol, choline and phosphatidyl choline that help to maintain healthy arteries. Lecithin also helps to reduce plaque in the arteries, lower blood pressure and ameliorate angina pectoris.

4. Niacin
Niacin a B3 vitamin, helps decreases blood levels of cholesterol and triglycerides which may reduce the risk of atherosclerosis. Niacin can only be taken under medical supervision because of it's side effects.

5. Selenium
Selenium deficiency will cause increase in high blood pressure.

6. Taurine
Taurine is an amino acid that acts as an antioxidant helping to fortify cardiac contraction and enhance the outflow of blood from the heart. Intake of taurine will reduce the risk of congestive heart failure and arteriosclerosis.

7. Calcium and potassium
Calcium and potassium deficiency may result in heart palpitation.

8. Magnesium
Magnesium helps to improve blood circulation by permitting the muscles in the arterial wall to rest.

9. Lutein
Lutein is one of the carotenoids, yellow and orange pigments found in many fruits and vegetables. Lutein supplementation has already been proven in helping prevent muscular degeneration, the most common cause of irreversible blindness in the elderly. Study shows that increased dietary intake of lutein may protect against the development of early atherosclerosis. It also helps explain why diets rich in fruits and vegetables are associated with reduced risk of heart disease.

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The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Causes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

The Causes

The causes of polycystic ovarian syndrome are still unknown(69)(70), but there are some suggestions
1. Genetic predisposition
A genetic predisposition is defined as a genetic mutation of some women who were born predisposed to certain health problems(75). In this case, it is polycystic ovarian syndrome(70)(71)(72)(73)(74) .

2. Insulin resistance(82)
Insulin resistance is defined as abnormal levels of insulin in the blood of a person found to be associated to women with PCOs(83). It may be caused by certain health problems such as diabetes(76)(77), abnormal function of pancreas(78)(79) or caused low numbers of the insulin sensitivity of cells(79)(80), which impair the process of glucose in energy conversion(81), induced high blood glucose levels in the body, cause of increasing the risks of ovarian cysts development(83).

3. Obesity(84)
Obesity is defined as a person whose BMI index is over 24. As we known, obesity women in most cases are associated to clinical feature of insulin resistance(76). According to Università Cattolica del Sacro Cuore, low 25(OH)D levels(86) accompanied with the degree of adiposity may induce the causation of PCOs(85).

4. Hyperandrogenism
Hyperandrogenism is a medical condition characterized by excessive production and/or secretion of androgens leading to male pattern hair growth, probably due to mutation in the polymorphism rs12720071 in women(88). According to Erciyes University, there is a relation between IR(Insulin resistance) and androgenetic alopecia (AGA)(87), a male pattern baldness.
Hirsutism develops when follicles in androgen sensitive areas start to form thick, pigmented hair as opposed to thin, short, non-pigmented hair normally seen in those areas in women with PCOs(89). Evaluating terminal hair growth on the chin or lower abdomen may be a reliable source for predicting hirsutism, according to Ahvaz Jundishapur University of Medical Sciences(90).

5. Environmental chemicals
Environment chemicals endocrine disruptors(91)(92), such as such as xanoestrogen, and lifestyle(91)(92) can causes over production of certain hormone and reduction of others, leading to abnormal function of the reproductive organs including the development of follicles and increasing the risk of PCOs(93).

6. Food adulteration
Food adulteration, including mixing, substituting, concealing the quality of food by mislabeling, putting up decomposed or expired food, and adding toxic substances(94) can lead to hormone imbalance(98) and distort the natural process of women reproductive system(97) and in same cases, result in death(95)(96).

7. Chronic inflammation
Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process(99)(100)(101).

8. Disorders of cortisol metabolism
Cortisol is usually referred to as the stress hormone, presented in high levels in patients with schizophrenia and bipolar disorder(104) as it is secreted in large volume for our body to response to stress and anxiety(103). Disorders of cortisol metabolism is defined as a condition of which cortisol hormone has lost its function in restoring glucose homeostasis(105) in balancing insulin and glucagon in the blood stream(107). According to University College London Hospitals, altered cortisol metabolism does not seem to be the primary cause of PCOS(102).


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)


(65) [Association between levels of serum leptin and insulin resistance in patients with polycystic ovary syndrome].[Article in Chinese]by Cheng X1, Guo J2, Xie J3.(PubMed)
(66) [Clinical study on treating insulin resistance and promoting ovulation in polycystic ovary syndrome].[Article in Chinese]by Liu ZA1, Xue YM, Chen LX, Cai Q, Chen H, Zhang J, Cui QH, Ge J, Yuan T.(PubMed)
(67) Randomized clinical trial evaluating metformin versus oral contraceptive pills in the treatment of adolescents with polycystic ovarian syndrome by Al-Zubeidi H, Klein KO.(PubMed)
(68) Randomized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome by Allen HF1, Mazzoni C, Heptulla RA, Murray MA, Miller N, Koenigs L, Reiter EO.(PubMed)
(69) [Polycystic ovary syndrome: physiopathology review].[Article in Spanish]by Fux Otta C, Fiol de Cuneo M, Szafryk de Mereshian P.(PubMed)
(70) Trp28Arg/Ile35Thr LHB gene variants are associated with elevated testosterone levels in women with polycystic ovary syndrome by Batista MC1, Duarte Ede F2, Borba MD3, Zingler E4, Mangussi-Gomes J3, dos Santos BT5, de Moraes OL5, Hayashida SA6, Baracat EC6, da Rocha Neves Fde A5, Maciel GA6, Bachega TA7, Barra GB8, Lofrano-Porto A9.(PubMed)
(71) Polycystic ovary syndrome woman with heterozygous androgen receptor genemutation who gave birth to a child with androgen insensitivity syndrome by Nam H1, Kim CH2, Cha MY1, Kim JM3, Kang BM1, Yoo HW3.(PubMed)
(72) The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS by Baculescu N1.(PubMed)
(73) Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome by Meczekalski B1, Nawrot R, Nowak W, Czyzyk A, Kedzia H, Gozdzicka-Jozefiak A.(PubMed)
(74) Association study of polymorphism of FXIIIVal34Leu gene and polycystic ovary syndrome by Wang X1, Yang Y1, Huang Y2, Wang Q3.(PubMed)
(75) Epigenetics and migraine; complex mitochondrial interactions contributing todisease susceptibility by Roos-Araujo D1, Stuart S1, Lea RA1, Haupt LM1, Griffiths LR2.(PubMed)
(76) Mechanisms linking obesity to insulin resistance and type 2 diabetes by Kahn SE1, Hull RL, Utzschneider KM.(PubMed)
(77) The effect of past antibiotic exposure on diabetes risk by Boursi B1, Mamtani R2, Haynes K3, Yang YX4.(PubMed)
(78) Portal versus systemic venous drainage of the pancreatic graft: the effect on glucose metabolism in pancreas and kidney transplant recipients by Havrdova T1, Boucek P2, Jedinakova T2, Lipar K3, Kocik M3, Skibova J4, Saudek F2.(PubMed)
(79) The mechanisms linking adiposopathy to type 2 diabetes by Yang J1, Kang J, Guan Y.(PubMed)
(80) Caffeic acid, naringenin and quercetin enhance glucose-stimulated insulinsecretion and glucose sensitivity in INS-1E cells by Bhattacharya S1, Oksbjerg N, Young JF, Jeppesen PB.(PubMed)
(81) Insulin resistance and adipogenesis: role of transcription and secreted factors by Penkov DN1, Egorov AD, Mozgovaya MN, Tkachuk VA.(PubMed)
(82) Insulin resistance in PCOS by Diamanti-Kandarakis E1(PubMed)
(83) Mouse models to study polycystic ovary syndrome: a possible link between metabolism and ovarian function? by van Houten EL1, Visser JA2.(PubMed)
(84)Epidemiologic investigation of polycystic ovarian syndrome (PCOS) in Han ethnic women of reproductive age in Liaoning Province, China by Jiao J, Fang Y, Wang T, Wang Z, Zhou M, Wang X.(PubMed)
(85) Low levels of 25(OH)D and insulin-resistance: 2 unrelated features or a cause-effect in PCOS?by Muscogiuri G1, Policola C, Prioletta A, Sorice G, Mezza T, Lassandro A, Della Casa S, Pontecorvi A, Giaccari A.(PubMed)
(86) Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome by Wehr E1, Pilz S, Schweighofer N, Giuliani A, Kopera D, Pieber TR, Obermayer-Pietsch B.(PubMed)
(87) The association of androgenetic alopecia and insulin resistance is independent of hyperandrogenemia: A case-control study by Kartal D1, Borlu M, Çınar SL, Ferahbaş A, Ulaş Y, Ünlühızarcı K, Ukşal Ü, Keleştimur F.(PubMed)
(88) GG genotype Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome by Jędrzejuk D1, Laczmański L, Kuliczkowska J, Lenarcik A, Trzmiel-Bira A, Hirnle L, Dorobisz U, Milewicz A, Lwow F, Urbanovych A, Słoka N.(PubMed)
(89) Women self-perception of excess hair growth, as a predictor of clinical hirsutism: a population-based study by Kazemi H1, Ramezani Tehrani F, Minooee S, Khalili D, Azizi F.(PubMed)
(90) Evaluation of only the chin or lower abdomen for predicting hirsutism by Rashidi H1, Parizi ZT, Mohammadi M.(PubMed)
(91) The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS) by Mick Rae, Cathal Grace, Kirsten Hogg, Lisa Marie Wilson, Sophie L. McHaffie,2 Seshadri Ramaswamy, Janis MacCallum, Fiona Connolly, Alan S. McNeilly,and Colin Duncan (PubMed)
(92) Prenatal androgen exposure leads to alterations in gene and protein expression in the ovine fetal ovary by Hogg K1, McNeilly AS, Duncan WC.(PubMed)
(93) Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction by Ewa L. Gregoraszczuk* and Anna Ptak(PubMed)
(94) Food Adulteration and Consumer Awareness in Dhaka City, 1995-2011 By Sharifa Nasreencorresponding author1 and Tahmeed Ahmed(PubMed)
(95) FAO/WHO. Assuring food safety and quality: guidelines for strengthening national food control systems. Rome: Food and Agriculture Organization; 2003. p. 28. (FAO food and nutrition paper no. 76).
(96) Park K. Park's textbook of preventive and social medicine. 18th ed. Jabalpur: Banarsidas Bhanot; 2005. p. 481.
(97) Menstrual effects among women exposed to polychlorinated biphenyls and dibenzofurans by Yang CY1, Huang TS, Lin KC, Kuo P, Tsai PC, Guo YL.(PubMed)
(98) Endocrine modulators in the food chain and environment by Nilsson R1.(PubMed)
(99) Adipose tissue dysfunction, adipokines and low-grade chronic inflammation inPCOS by Spritzer PM1, Lecke SB2, Satler F3, Morsch DM4.(PubMed)
(100) Adipose tissue dysfunction in polycystic ovary syndrome by Villa J1, Pratley RE.(PubMed)
(101) Adipose tissue, metabolic syndrome and polycystic ovary syndrome: from pathophysiology to treatment by Garruti G1, Depalo R, Vita MG, Lorusso F, Giampetruzzi F, Damato AB, Giorgino F.(PubMed)
(102) Altered cortisol metabolism in polycystic ovary syndrome: insulin enhances 5alpha-reduction but not the elevated adrenal steroid production rates by Tsilchorozidou T1, Honour JW, Conway GS.(PubMed)
(103) Increased testosterone levels and cortisol awakening responses in patients with borderline personality disorder: Gender and trait aggressiveness matter by Rausch J1, Gäbel A1, Nagy K1, Kleindienst N2, Herpertz SC1, Bertsch K3.(PubMed|)
(104) Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability? by Steen NE1, Methlie P, Lorentzen S, Hope S, Barrett EA, Larsson S, Mork E, Almås B, Løvås K, Agartz I, Melle I, Berg JP, Andreassen OA.(PubMed)
(105) Elevated maternal cortisol leads to relative maternal hyperglycemia and increased stillbirth in ovine pregnancy by Keller-Wood M1, Feng X2, Wood CE3, Richards E2, Anthony RV4, Dahl GE5, Tao S5.(PubMed)
(106) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man by Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC.(PubMed)
(107) Glucose Homeostasis and Starvation(Glucose Homeostasis)

Herbal therapy: Popular Herbal Fennel (Foeniculum vulgare)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

               Fennel (Foeniculum vulgare)

Fennel (Foeniculum vulgare) is a plant species of genus, belonging toApiaceae (Umbelliferae), native to the Mediterranean. It has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS, etc.

Health Benefits
1. Antioxidant activity
In the study of Fennel and it antioxidant effects found that fennel seems a new antioxidant for use in sperm cryopreservation, but its particular effects on sperm physiology must be further studied, especially the causes of motility stimulation and its effect on lipoxidation, according to "Fennel (Foeniculum vulgare) provides antioxidant protection for boar semen cryopreservation" by Malo C, Gil L, Cano R, González N, Luño V.(1)

2. Peptic ulcer
In the investigation of phenolic compounds of herbal plants, including toFoeniculum vulgare and theirs effect on human health found that various polyphenolic compounds have been reported for their anti-ulcerogenic activity with a good level of gastric protection. Besides their action as gastroprotective, these phenolic compounds can be an alternative for the treatment of gastric ulcer, according to "Role of phenolic compounds in peptic ulcer: An overview" by Sumbul S, Ahmad MA, Mohd A, Mohd A.(2)

3. Digestive system
In the investigation of ginger, peppermint, aniseed and fennel, citrus fruits, dandelion and artichoke, melissa and chamomile and theirs effect on digestive disturbances and ailments found that The plants that have a substantial body of data in support of their digestion-enhancing activities mainly belong to one of three groups: bitter, aromatic and pungent plants, including fenel, according to "Functional foods with digestion-enhancing properties" by Valussi M.(3)

4. Anti cancers
In the observation of methanolic extract and volatile oil of fennel seeds and its anti cancer effect found that the FSME exhibited an antitumor effect by modulating lipid peroxidation and augmenting the antioxidant defense system in EAC-bearing mice with or without exposure to radiation, according to "Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare)" by Mohamad RH, El-Bastawesy AM, Abdel-Monem MG, Noor AM, Al-Mehdar HA, Sharawy SM, El-Merzabani MM.(4)

5. Antimicrobial activity
In the identification of The essential oils extracted from thyme (Thymus vulgaris L.), basil (Ocimum basilicum L.), coriander (Coriandrum sativum L.), rosemary (Rosmarinus officinalis L.), sage (Salvia officinalis L.), fennel (Foeniculum vulgare L.), spearmint (Mentha spicata L.) and carraway (Carum carvi L.) and theirs anti microbial effects found that the majority of the tested essential oils exhibited considerable inhibitory capacity against all the organisms tested, according to "Antimicrobial activity of plant essential oils against bacterial and fungal species involved in food poisoning and/or food decay" by Lixandru BE, Drăcea NO, Dragomirescu CC, Drăgulescu EC, Coldea IL, Anton L, Dobre E, Rovinaru C, Codiţă I.(5)

6. Urinary system
In a historical review of urological pharmacotherapy including drumstick tree, agaricus, mechoacan, lupine, fennel, acacia gum, myrtle, Armenian bole, oleum scorpionum, hartshorn plantain, cantharides found that The basis of general and urological pharmacotherapy was concentrated on nature. Medicines of plant origin were the most used. The therapeutic inventory that mankind has accumulated throughout history is the result of a lengthy process of combining practices and knowledge of different cultures and societies, according to "[Contribution to the history of urological pharmacotherapy].[Article in Spanish]" by Mercant J.(6)

7. Antiadhesive activity
In the analyzing herbal medicine, including Foeniculum vulgare (fennel) and theirs anti-Campylobacter effects found that twenty-one herbal extracts were screened for antiadhesive activity against C. jejuni using modifications of previously published antiadhesion assays, according to "Investigations into the antiadhesive activity of herbal extracts against Campylobacter jejuni" by Bensch K, Tiralongo J, Schmidt K, Matthias A, Bone KM, Lehmann R, Tiralongo E.(7)

8. Parasitic effects
In the observation of the nematicidal activity and the chemical composition of essential oils (EOs) isolated from seven plants grown in Greece and their anti parasitic effects found that the activity of F. vulgare, P. anisum, E. meliodora and P. terebinthus, and additionally on synergistic/antagonistic nematicidal terpene interactions, against M. incognita, providing alternative methods for nematode control, according to "Synergistic and antagonistic interactions of terpenes against Meloidogyne incognita and the nematicidal activity of essential oils from seven plants indigenous to Greece" by Ntalli NG, Ferrari F, Giannakou I, Menkissoglu-Spiroudi U.(8)

9. Immunotoxicity activity
In the demonstration of The extract and essential oil composition of leaves ofFoeniculum vulgare (Umbelliferae) the major essential oil composition and theirs Immunotoxicity activity found that indicate that major compounds interaction may play a more important role in the toxicity of essential oil against the F(21) laboratory strain of A. aegypti, according to "Major essential oils composition and immunotoxicity activity from leaves of Foeniculum vulgare against Aedes aegypti L.' by Chung IM, Ro HM, Moon HI.(9)

10. Diabetes
In the investigation of , rho-isoalpha acids, Acacia nilotica bark, fennel, and wasab and theirs anti diabetes effect found that All 21 subset samples inhibited TNFalpha-stimulated free fatty acid release and attenuated TNFalpha inhibition of adiponectin secretion. Both rho-isoalpha acids and A. nilotica reduced nonfasting glucose in the db/db mouse model, whereas A. nilotica also decreased nonfasting insulin levels, according to "Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice" by Babish JG, Pacioretty LM, Bland JS, Minich DM, Hu J, Tripp ML.(10)

11. Estragole metabolism
in the research of the metabolism of the potent carcinogen estragole after consumption of fennel tea found that an excess of the major fennel odorant trans-anethole principally does not interfere with estragole metabolism, whereas influences on the quantitative composition of metabolites cannot be excluded. The presence of a sulfuric acid conjugate of estragole could not be confirmed, possibly due to its high reactivity and lability, according to "Study of the metabolism of estragole in humans consuming fennel tea" by Zeller A, Horst K, Rychlik M.(11)

12. Obesity
in the consideration of L-carnitine and an Egyptian Herbal mixture formulation (HMF) (consisting of T. chebula, Senae, rhubarb, black cumin, aniseed, fennel and licorice) and theirs effect on the development of obesity in response to a high fat diet (HFD) found that Treatment with L-carnitine, or HMF extract improved obesity and its associated metabolic problems in different degrees. Also HMF has antioxidant, hypolipidaemic insulin sensitizing effects. Moreover HMF might be a safe combination on the organs whose functions were examined, as a way to surmount the obesity state; and it has a distinct anti-obesity effect, according to "Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats" by Amin KA, Nagy MA.(12)

13. Etc.

Side effects
1. Epileptic seizure
Essential oil may cause Epileptic seizure and should probably be avoided by patients with epilepsy, according to "Epileptic seizure induced by fennelessential oil" by

Skalli S, Soulaymani Bencheikh R.(a)
2. Overdose may cause nervous tension and vomiting , upset stomach & convulsions
3. Fennel may cause photo and dermatitis
4. Do not use the herb if you are pregnant or breast feeding without permission of related field specialist.
5. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22106928
(2) http://www.ncbi.nlm.nih.gov/pubmed/21966156
(3) http://www.ncbi.nlm.nih.gov/pubmed/22010973
(4) http://www.ncbi.nlm.nih.gov/pubmed/21812646
(5) http://www.ncbi.nlm.nih.gov/pubmed/21462837
(6) http://www.ncbi.nlm.nih.gov/pubmed/21292351
(7) http://www.ncbi.nlm.nih.gov/pubmed/21280113
(8) http://www.ncbi.nlm.nih.gov/pubmed/21170935
(9) http://www.ncbi.nlm.nih.gov/pubmed/21077804
(10) http://www.ncbi.nlm.nih.gov/pubmed/20521979
(11) http://www.ncbi.nlm.nih.gov/pubmed/19908891
(12) http://www.ncbi.nlm.nih.gov/pubmed/19835614

Most common Diseases of 50plus: Heart Disease(The Articles) - The Phytochemicals

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                  Heart Disease

Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease. There are many causes of heart disease. Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.


Phytochemicals and Heart Diseases

Heart diseases are caused by high blood pressure that contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. Therefore, in order to lower the risk of heart diseases foods consumed in everyday diet become one of many important factors. Here are some foods can actually lower high blood pressure and levels of cholesterol resulting in lowering the risk of heart diseases

1. Fresh water algae
Fresh water algae contains chlorophyII-rich foods that is a powerful antioxidant for protection of build up of free radicals and restoring DNA of damaged cells. It also contains high amounts of Omega 3 and 6 fatty acids that can help to maintain normal blood pressure as well as cholesterol levels. Omega 3 and 6 fatty acids also inhibit blood clotting that causes the blockage of arteries and heart diseases.

2. Onions and garlic
Garlic and onions contain high amounts of sulfur compounds that not only help to improve circulation of blood but also help to keep your platelets from clumping together. Daily consumption of both garlic and onions help to keep blood pressure and cholesterol levels in healthy range. Be sure to talk to your doctor if you are taking any blood thinner medicines.

3. Nuts and seeds
Nuts and seeds contain high amounts of unsaturated fat and vitamin E. Unsaturated fat helps to prevent clots of arteries and lower cholesterol levels. Vitamin E, and the antioxidants beta varotene on the other hand stops bad cholesterol LDL from building up in the arteries, decreasing the risk of heart attacks.

4. Vegetables and fruits
Vegetable and fruits contain high amounts vitamins A, E, C and B. Vitamin E, the antioxidants beta carotene and vitamin C help to strengthen your small blood vessels and thins your blood so it can flow smoothly in result of lowering the risk ofheart disease and strokes. Plums, tomatoes, and watercress are the best choices.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Most Common Diseases of elder: Respiratory Disease: Benign lung tumors - The Diagnosis and tests

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).


                     Diagnosis and tests

Most case of lung tumors are found accidentally in chest X ray.
Solitary pulmonary nodule represents 0.2% of incidental findings in routine chest X-ray images. One of the main diagnoses includes lung cancer in which small-cell subtype has a poor survival rate. Recently, a new classification has been proposed including the very limited disease stage (VLD stage) or T1-T2N0M0 with better survival rate, specifically in those patients who are treated with surgery(15).
The aim of the differentiation is to prevent the spreading of the lung nodules if they have become malignancy
1. Comparison chest X ray and repeat chest X ray
The lung tumor will be compared with chest X ray taken in last year for the potentail of malidnancy.
If lung nodule found in the X ray is new and can not be compared than Repeat chest X ray if your doctor suspected that nodule is likely benign.

2. Bronchoscopy
In the study in comparison of transbronchial needle aspiration (TBNA) with cytology brush and forceps biopsy, in the diagnosis of a pulmonary mass or coin lesions has been studied by Shure and Wang in the past, found that the needle brush and TBNA have a higher diagnostic yield in malignant lung masses or nodules. The use of regular brush and forceps biopsy did not increase the diagnostic yield in malignancy. Forceps biopsy might be more useful in benign diseases(15a).
3. Biopsy, Thoracoscopy and neodymium:yttrium-aluminum garnet laser
Between January 1991 and June 1992, 242 patients with indeterminate solitarylung nodules underwent thoracoscopic excisional biopsy as the primary diagnostic method. Wedge excisions of the nodules were all performed by thoracoscopic techniques using an endoscopic stapler alone (72%), neodymium:yttrium-aluminum garnet laser (18%), or both (10%)(16).

4. CT scan
Proposed is a method for statistical analysis for a small sample size, repeated measure experiment with nesting factors. In the original experiment the Student t-test was used for analysis. Using the same data, we modeled the experiment into two groups of mice with benign and malignant primary lung tumors. 4 tumor nodules were selected from each mouse (N= 36). The dependent variables are the volume, diameter, and signal attenuation measured using computed tomography(CT), according to the study by The University of Texas Health Sciences Center at Houston, Houston(17).

5. Radial EBUS navigation
In the study to examine the sensitivity and factors that may impact the diagnostic yield of a similar technology, namely, radial endobronchial ultrasound (EBUS), found that lesion size, distance, presence of a computerized tomography bronchus sign, or lobar location may not impact the diagnostic yield of bronchoscopic biopsy of peripheral lung nodules with radial EBUS navigation(18).

6. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(15) http://www.ncbi.nlm.nih.gov/pubmed/22345914
(15a) http://www.ncbi.nlm.nih.gov/pubmed/1914576
(16) http://www.ncbi.nlm.nih.gov/pubmed/8215658
(17) http://www.ncbi.nlm.nih.gov/pubmed/23304269
(18) http://www.ncbi.nlm.nih.gov/pubmed/23207256