Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
In the presents the highlights of an advisory report on the prevention and treatment of overweight and obesity, produced by the Health Council of The Netherlands,
researchers indicated that healthy diet (including plenty of fruit, vegetables and cereal products) and at least one hour a day of moderate physical activity are recommended for the maintenance of energy balance and for the prevention of weight gain. While genetic factors play a part in the development of overweight and obesity, environmental factors appear to be of overriding importance. The so-called 'obesogenic environment' prompts individuals to eat more and to take less exercise. There are still no effective intervention strategies for the prevention of weight gain. However, the explosive increase in the prevalence of obesity and of its associated serious medical problems demands a common-sense approach involving preventive interventions, which are based on modern views of health promotion. These interventions require a broad coalition of actors, in which local and national authorities, industry, the healthcare system and the population at risk must each shoulder their own share of responsibility. The primary aim of obesity treatment should be a long-lasting weight loss of about 10%. Even this relatively small weight loss can produce significant health gains. Treatment methods must involve an integrated (lifestyle) approach, dependent on the amount of overweight involved and on the presence of comorbidity. Obesity should be treated chronically and prevention of weight regain must be part of any obesity treatment programme.(1)
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1) "The prevention and treatment of overweight and obesity. Summary of the advisory report by the Health Council of The Netherlands" by Kemper HC, Stasse-Wolthuis M, Bosman W.
Thursday, June 9, 2016
Wednesday, June 8, 2016
Phytochemicals in Foods - The Effects of Betulinic acid
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Betulinic acid
Betulinic acid is a phytochemincal in the subclass of Triterpenoid, belonging to the group of Terpenes found abundantly in Ber tree, white birch, rosemary etc.
Health Benefits
1. Colorectal cancer
In the investigation of the enhancement of Betulinic acid (BA) cytotoxicity by α-mangostin, and the cytoprotection effect of α-mangostin and BA on cisplatin-induced cytotoxicity on HCT 116 human colorectal carcinoma cells, found that α-Mangostin and BA were more cytotoxic to the colon cancer cells than to the normal colonic cells, and both compounds showed a cytoprotective effect against cisplatin-induced cytotoxicity. On the other hand, α-mangostin enhanced the cytotoxic and apoptotic effects of BA. Combination therapy hits multiple targets, which may improve the overall response to the treatment, and may reduce the likelihood of developing drug resistance by the tumor cells, according to 'α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells" by Aisha AF, Abu-Salah KM, Ismail Z, Majid AM.(1)
2. Anti cancers
In the identifitification of the agent as potently effective against a wide variety of cancer cells, also those derived from therapy-resistant and refractory tumors, found that In-vivo preclinically applied BetA showed some remarkable anticancer effects and a complete absence of systemic toxicity in rodents. BetA also cooperated with other therapies to induce tumor cell death and several potent derivatives have been discovered. Its antitumor activity has been related to its direct effects on mitochondria where it induces Bax/Bak-independent cytochrome-c release, according to 'Betulinic acid, a natural compound with potent anticancer effects" by Mullauer FB, Kessler JH, Medema JP.(2)
3. Anti inflammatory effects
In the investigation of the effect of betulinic acid (BA) on acute lung damage induced by bacterial endotoxin (lipopolysaccharide, LPS) in male Sprague-Dawley rats, found that Treatment with BA was found to significantly attenuate all these alterations. The present results suggest that BA is endowed with antiinflammatory and antioxidant properties that protect the lung against the deleterious actions of LPS, according to 'Effect of betulinic acid on neutrophil recruitment and inflammatory mediator expression in lipopolysaccharide-induced lung inflammation in rats" by Nader MA, Baraka HN.(3)
4. Ovarian Cancer
In elucidation of the effect of BH3-only proteins on cisplatin-resistant ovarian cancer cells,
indicate that Puma plays a critical role in the apoptosis of chemo-resistant ovarian cancer cells treated with betulinic acid (BetA). The reduction of Puma expression inhibits Bax activation and apoptosis, according to "JNK and Akt-mediated Puma Expression in the Apoptosis of Cisplatin-resistant Ovarian Cancer Cells" by Zhao Z, Wang J, Tang J, Liu X, Zhong Q, Wang F, Hu W, Yuan Z, Nie C, Wei Y.(4)
5. Anti-fibrotic effect
In the to investigation of the anti-fibrotic effect and the potential mechanisms of action of betulinic acid (BA) against hepatic fibrosis in vivo and in vitro, showed that BA effectively decreased the HSC-T6 cell viability induced by TNF-α and showed low toxicity in normal human chang liver cells. Moreover, BA significantly attenuated the expression of α-SMA and tissue inhibitor of metalloproteinase-1 (TIMP-1) and increased the levels of matrix metalloprotease (MMP)-13. BA also inhibited the expression of Toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) and the activation of nuclear factor-κB (NF-κB) in a time-dependent manner, according to 'The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation" by Wan Y, Wu YL, Lian LH, Xie WX, Li X, Ouyang BQ, Bai T, Li Q, Yang N, Nan JX.(5)
6. Antifungal metabolites
In the investigation of the Antifungal effects of two new natural compounds, 4-hydroxy-5,6-dimethoxynaphthalene-2-carbaldehyde (1) and 12,13-didehydro-20,29-dihydrobetulin (2) together with nine known compounds, including 7-methyljuglone (3), diospyrin (4), isodiospyrin (5), shinanolone (6), lupeol (7), betulin (8), betulinic acid (9), betulinaldehyde (10), and ursolic acid (11) from the acetone extract of the roots of Diospyros virginiana, found that All the isolated compounds were evaluated for their antifungal activities against Colletotrichum fragariae, C. gloeosporioides, C. acutatum, Botrytis cinerea, Fusarium oxysporum, Phomopsis obscurans, and P. viticola using in vitro micro-dilution broth assay, according to'Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography" by Wang X, Habib E, León F, Radwan MM, Tabanca N, Gao J, Wedge DE, Cutler SJ.(6)
7. Antileukemic activity
In an easy and efficient route to partial synthesis of bioactive 28-hydroxy-3-oxolup-20(29)-en-30-al (1), starting from betulinic acid (2), found that Compound 1 and the precursors (2, 3, 5, and 7) showed antiproliferative activities against human K562 leukemia, murine WEHI3 leukemia, and murine MEL erythroid progenitor, according to 'Synthesis of bioactive 28-hydroxy-3-oxolup-20(29)-en-30-al with antileukemic activity by Ghosh P, Mandal A, Ghosh J, Pal C, Nanda AK.(7)
8. HIV maturation inhibitor
In the study of triterpene derivatives as potent anti-HIV agents, different C-3 conformationally restricted betulinic acid (BA, 1) derivatives were designed and synthesized in order to explore the conformational space of the C-3 pharmacophore. 3-O-Monomethylsuccinyl-betulinic acid (MSB) analogues were also designed to better understand the contribution of the C-3' dimethyl group of bevirimat (2), the first-in-class HIV maturation inhibitor, which is currently in phase IIb clinical trials. In addition, another triterpene skeleton, moronic acid (MA, 3), was also employed to study the influence of the backbone and the C-3 modification toward the anti-HIV activity of this compound class, may lead to led to the design and synthesis of compound 12 (EC(50): 0.0006 microM), which displayed slightly better activity than 2 as a HIV-1 maturation inhibitor, according to " Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors" by Qian K, Kuo RY, Chen CH, Huang L, Morris-Natschke SL, Lee KH.(8)
9. Cytokine production and proliferation of CD4(+) T cells and CD19(+) B cells
In the examination of the effects of the triterpene acid mixture on the cytokine production and proliferation of CD4(+) T cells and CD19(+) B cells induced by a self-antigen, human thyroglobulin and by lipopolysaccharide in cultures of normal mononuclear cells, found that the mixture also inhibited CD4(+) T-cell and CD19(+) B-cell proliferation (IC(50) value 22 and 12 µg/mL, respectively). Together, these data demonstrate that oleanolic, ursolic and betulinic acid are active immunomodulatory constituents of the standardized rose hip powder, according to "Triterpene Acids from Rose Hip Powder Inhibit Self-antigen- and LPS-induced Cytokine Production and CD4(+) T-cell Proliferation in Human Mononuclear Cell Cultures" by Saaby L, Nielsen CH.(9)
10. Antiobesity effects
In the investigation of the antilipase function of betulinic acid, the ability ofbetulinic acid to inhibit pancreatic lipase activity in vitro and and prevention of the elevation of plasma triacylglycerol levels tested after oral administration of a lipid emulsion in rats, suggested that betulinic acid may exert antiobesity effects by directly inhibiting pancreatic lipase, which would prevent the absorption of lipid from the small intestine. In addition, it was found that betulinic acid may further accelerate fat mobilization by enhancing the levels of lipolysis in adipose tissues, according to "Betulinic Acid has an Inhibitory Effect on Pancreatic Lipase and Induces Adipocyte Lipolysis" by Kim J, Lee YS, Kim CS, Kim JS.(10)
11. Antimicrobial activity
In the investigation of the extract from of the isolation from leaves of Clusia burlemarxii, (3-O-α-L- rhamnopyranosylquercetin, 3-O-α-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-δ-tocotrienoloic acid and friedelin) and from trunk (betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane), found that the extracts and compounds showed significant activity against tested Gram-positive bacteria, none activity against tested Gram-negative bacteria and fungi, according to "A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii" by Ribeiro PR, Ferraz CG, Guedes ML, Martins D, Cruz FG.(11)
12. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22402764
(2) http://www.ncbi.nlm.nih.gov/pubmed/20075711
(3) http://www.ncbi.nlm.nih.gov/pubmed/22402186
(4) http://www.ncbi.nlm.nih.gov/pubmed/22394200
(5) http://www.ncbi.nlm.nih.gov/pubmed/22285267
(6) http://www.ncbi.nlm.nih.gov/pubmed/22162171
(7) http://www.ncbi.nlm.nih.gov/pubmed/22166062
(8) http://www.ncbi.nlm.nih.gov/pubmed/20329730
(9) http://www.ncbi.nlm.nih.gov/pubmed/22170858
(10) http://www.ncbi.nlm.nih.gov/pubmed/22114077
(11) http://www.ncbi.nlm.nih.gov/pubmed/21893172
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Betulinic acid
Betulinic acid is a phytochemincal in the subclass of Triterpenoid, belonging to the group of Terpenes found abundantly in Ber tree, white birch, rosemary etc.
Health Benefits
1. Colorectal cancer
In the investigation of the enhancement of Betulinic acid (BA) cytotoxicity by α-mangostin, and the cytoprotection effect of α-mangostin and BA on cisplatin-induced cytotoxicity on HCT 116 human colorectal carcinoma cells, found that α-Mangostin and BA were more cytotoxic to the colon cancer cells than to the normal colonic cells, and both compounds showed a cytoprotective effect against cisplatin-induced cytotoxicity. On the other hand, α-mangostin enhanced the cytotoxic and apoptotic effects of BA. Combination therapy hits multiple targets, which may improve the overall response to the treatment, and may reduce the likelihood of developing drug resistance by the tumor cells, according to 'α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells" by Aisha AF, Abu-Salah KM, Ismail Z, Majid AM.(1)
2. Anti cancers
In the identifitification of the agent as potently effective against a wide variety of cancer cells, also those derived from therapy-resistant and refractory tumors, found that In-vivo preclinically applied BetA showed some remarkable anticancer effects and a complete absence of systemic toxicity in rodents. BetA also cooperated with other therapies to induce tumor cell death and several potent derivatives have been discovered. Its antitumor activity has been related to its direct effects on mitochondria where it induces Bax/Bak-independent cytochrome-c release, according to 'Betulinic acid, a natural compound with potent anticancer effects" by Mullauer FB, Kessler JH, Medema JP.(2)
3. Anti inflammatory effects
In the investigation of the effect of betulinic acid (BA) on acute lung damage induced by bacterial endotoxin (lipopolysaccharide, LPS) in male Sprague-Dawley rats, found that Treatment with BA was found to significantly attenuate all these alterations. The present results suggest that BA is endowed with antiinflammatory and antioxidant properties that protect the lung against the deleterious actions of LPS, according to 'Effect of betulinic acid on neutrophil recruitment and inflammatory mediator expression in lipopolysaccharide-induced lung inflammation in rats" by Nader MA, Baraka HN.(3)
4. Ovarian Cancer
In elucidation of the effect of BH3-only proteins on cisplatin-resistant ovarian cancer cells,
indicate that Puma plays a critical role in the apoptosis of chemo-resistant ovarian cancer cells treated with betulinic acid (BetA). The reduction of Puma expression inhibits Bax activation and apoptosis, according to "JNK and Akt-mediated Puma Expression in the Apoptosis of Cisplatin-resistant Ovarian Cancer Cells" by Zhao Z, Wang J, Tang J, Liu X, Zhong Q, Wang F, Hu W, Yuan Z, Nie C, Wei Y.(4)
5. Anti-fibrotic effect
In the to investigation of the anti-fibrotic effect and the potential mechanisms of action of betulinic acid (BA) against hepatic fibrosis in vivo and in vitro, showed that BA effectively decreased the HSC-T6 cell viability induced by TNF-α and showed low toxicity in normal human chang liver cells. Moreover, BA significantly attenuated the expression of α-SMA and tissue inhibitor of metalloproteinase-1 (TIMP-1) and increased the levels of matrix metalloprotease (MMP)-13. BA also inhibited the expression of Toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) and the activation of nuclear factor-κB (NF-κB) in a time-dependent manner, according to 'The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation" by Wan Y, Wu YL, Lian LH, Xie WX, Li X, Ouyang BQ, Bai T, Li Q, Yang N, Nan JX.(5)
6. Antifungal metabolites
In the investigation of the Antifungal effects of two new natural compounds, 4-hydroxy-5,6-dimethoxynaphthalene-2-carbaldehyde (1) and 12,13-didehydro-20,29-dihydrobetulin (2) together with nine known compounds, including 7-methyljuglone (3), diospyrin (4), isodiospyrin (5), shinanolone (6), lupeol (7), betulin (8), betulinic acid (9), betulinaldehyde (10), and ursolic acid (11) from the acetone extract of the roots of Diospyros virginiana, found that All the isolated compounds were evaluated for their antifungal activities against Colletotrichum fragariae, C. gloeosporioides, C. acutatum, Botrytis cinerea, Fusarium oxysporum, Phomopsis obscurans, and P. viticola using in vitro micro-dilution broth assay, according to'Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography" by Wang X, Habib E, León F, Radwan MM, Tabanca N, Gao J, Wedge DE, Cutler SJ.(6)
7. Antileukemic activity
In an easy and efficient route to partial synthesis of bioactive 28-hydroxy-3-oxolup-20(29)-en-30-al (1), starting from betulinic acid (2), found that Compound 1 and the precursors (2, 3, 5, and 7) showed antiproliferative activities against human K562 leukemia, murine WEHI3 leukemia, and murine MEL erythroid progenitor, according to 'Synthesis of bioactive 28-hydroxy-3-oxolup-20(29)-en-30-al with antileukemic activity by Ghosh P, Mandal A, Ghosh J, Pal C, Nanda AK.(7)
8. HIV maturation inhibitor
In the study of triterpene derivatives as potent anti-HIV agents, different C-3 conformationally restricted betulinic acid (BA, 1) derivatives were designed and synthesized in order to explore the conformational space of the C-3 pharmacophore. 3-O-Monomethylsuccinyl-betulinic acid (MSB) analogues were also designed to better understand the contribution of the C-3' dimethyl group of bevirimat (2), the first-in-class HIV maturation inhibitor, which is currently in phase IIb clinical trials. In addition, another triterpene skeleton, moronic acid (MA, 3), was also employed to study the influence of the backbone and the C-3 modification toward the anti-HIV activity of this compound class, may lead to led to the design and synthesis of compound 12 (EC(50): 0.0006 microM), which displayed slightly better activity than 2 as a HIV-1 maturation inhibitor, according to " Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors" by Qian K, Kuo RY, Chen CH, Huang L, Morris-Natschke SL, Lee KH.(8)
9. Cytokine production and proliferation of CD4(+) T cells and CD19(+) B cells
In the examination of the effects of the triterpene acid mixture on the cytokine production and proliferation of CD4(+) T cells and CD19(+) B cells induced by a self-antigen, human thyroglobulin and by lipopolysaccharide in cultures of normal mononuclear cells, found that the mixture also inhibited CD4(+) T-cell and CD19(+) B-cell proliferation (IC(50) value 22 and 12 µg/mL, respectively). Together, these data demonstrate that oleanolic, ursolic and betulinic acid are active immunomodulatory constituents of the standardized rose hip powder, according to "Triterpene Acids from Rose Hip Powder Inhibit Self-antigen- and LPS-induced Cytokine Production and CD4(+) T-cell Proliferation in Human Mononuclear Cell Cultures" by Saaby L, Nielsen CH.(9)
10. Antiobesity effects
In the investigation of the antilipase function of betulinic acid, the ability ofbetulinic acid to inhibit pancreatic lipase activity in vitro and and prevention of the elevation of plasma triacylglycerol levels tested after oral administration of a lipid emulsion in rats, suggested that betulinic acid may exert antiobesity effects by directly inhibiting pancreatic lipase, which would prevent the absorption of lipid from the small intestine. In addition, it was found that betulinic acid may further accelerate fat mobilization by enhancing the levels of lipolysis in adipose tissues, according to "Betulinic Acid has an Inhibitory Effect on Pancreatic Lipase and Induces Adipocyte Lipolysis" by Kim J, Lee YS, Kim CS, Kim JS.(10)
11. Antimicrobial activity
In the investigation of the extract from of the isolation from leaves of Clusia burlemarxii, (3-O-α-L- rhamnopyranosylquercetin, 3-O-α-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-δ-tocotrienoloic acid and friedelin) and from trunk (betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane), found that the extracts and compounds showed significant activity against tested Gram-positive bacteria, none activity against tested Gram-negative bacteria and fungi, according to "A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii" by Ribeiro PR, Ferraz CG, Guedes ML, Martins D, Cruz FG.(11)
12. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22402764
(2) http://www.ncbi.nlm.nih.gov/pubmed/20075711
(3) http://www.ncbi.nlm.nih.gov/pubmed/22402186
(4) http://www.ncbi.nlm.nih.gov/pubmed/22394200
(5) http://www.ncbi.nlm.nih.gov/pubmed/22285267
(6) http://www.ncbi.nlm.nih.gov/pubmed/22162171
(7) http://www.ncbi.nlm.nih.gov/pubmed/22166062
(8) http://www.ncbi.nlm.nih.gov/pubmed/20329730
(9) http://www.ncbi.nlm.nih.gov/pubmed/22170858
(10) http://www.ncbi.nlm.nih.gov/pubmed/22114077
(11) http://www.ncbi.nlm.nih.gov/pubmed/21893172
The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: Antioxidants Bilirubin and Carotenoids
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
The Antioxidants
1. Bilirubin
Bilirubin is a prosthetic group helped to break down molecules into smaller units in releasing energy, excreted in bile and urine. It is a cellular antioxidant(511), by reverting to biliverdin, a green tetrapyrrolic bile pigment, once again when oxidized, it inhibits the effects of mutagens(512). The antioxidant showed to inhibit digestive proteases like trypsin and chymotrypsin(504), benefit heart health(505) and nonalcoholic fatty liver disease(507), reduce risk of diabetes(506). Recent studies also found that the antioxidant exhibits its anti inflammatory effects(511) against certain chronic inflammatory diseases, including psoriasis(508), chronic obstructive pulmonary disease(509), .... and enhances immunity activities(510)
2. Carotenoids
Carotenoids are organic pigments, occurring in the chloroplasts and chromoplasts(513) of plants and some photosynthetic organisms like algae and bacteria(514).
a. Beta-carotene
Beta-carotene, an organic compound classified as a terpenoid, is a strongly-coloured red-orange pigment in plants and fruits, stored in liver for the production of vitamin A. Epidemiological evidences sugested that beta-carotene neutralizes singlet oxygen before giving rise of free radicals(515) which can damage of DNA, leading to improper cell DNA replication(516)(517), causing irregual cells growth, such as cancers(518)(519)(520). The phytochemical also promotes immunity(521)(522) against foreign invasion and symptoms of chronic inflammatory disease(523)(524) and improve low-density lipoprotein cholesterol resistance to oxidation causes of cardiovascular disease related to atherosclerosis(527) through its antioxidant anti inflammatory activities(525)(526).....
b. Alpha-carotene
Alpha-carotene, one of the most abundant carotenoids in the North American diet, is a form of carotene with a β-ring at one end and an ε-ring at the other, not only protects cells from the damaging effects of free radicals(526) and enhances the immune system(528) in fighting against bacteria and virus infection and inflammation(529)(530), but also inhibits irregular cell growth(531)(532) cause of benign tumors(531) and cancers(532).
c. Beta-cryptoxanthin
Chemically Beta-cryptoxanthin is a xanthophyll which protects our cells from oxidation(538) and provides a source of vitamin A. The phytochemical showed to enhances the immune system functioning(533)(534) against infectious(537) and inflammatory diseases(535)(536) and reduces insulin resistance(536) and cancers(539)(540) risks
d. Lycopene
Lycopene is a red carotene of the carotenoids group found in tomatoes, watermelons, and grapefruits. This antioxidant is believed to be a powerful fighter against irregular growth(543), such as prostate cancer(541)(542), breast cancer(544)(545) and liver diseases(546)(547). Lycopene has many anti-aging(549) capabilities as well as enhancing immune function(548) against oxidative stress(550)(551) and inflammatory diseases(551)(552).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatorydiseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(507) Serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease by Kwak MS1, Kim D, Chung GE, Kang SJ, Park MJ, Kim YJ, Yoon JH, Lee HS.(PubMed)
(508) Antioxidant status in patients with psoriasis by Nemati H, Khodarahmi R, Sadeghi M, Ebrahimi A, Rezaei M, Vaisi-Raygani A.(PubMed)
(509) Serum Bilirubin and Disease Progression in Mild Chronic Obstructive Pulmonary Disease by Apperley S, Park HY, Holmes DT, Man SF, Tashkin D, Wise RA, Connett JE, Sin DD.(PubMed)(510) Cellular-mediated immune responses in the liver tissue of patients with severe Plasmodiumfalciparum malaria by Punsawadl C, Setthapramote C, Viriyavejakul P.(PubMed)
(511) Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration by Bulmer AC1, Coombes JS, Blanchfield JT, Toth I, Fassett RG, Taylor SM.(PubMed)
(512) Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide by Mölzer C1, Huber H, Steyrer A, Ziesel GV, Wallner M, Hong HT, Blanchfield JT, Bulmer AC, Wagner KH.(PubMed)
(513) Confocal laser scanning microscopy detection of chlorophylls and carotenoids in chloroplasts and chromoplasts of tomato fruit by D'Andrea L1, Amenós M, Rodríguez-Concepción M.(PubMed)
(514) Carotenoids(Wikipedia)
(515) Lycopene Inhibits the Isomerization of β-Carotene during Quenching of Singlet Oxygen and Free Radicals by Heymann T1, Heinz P1, Glomb MA1.(PubMed)
(516) Wood smoke particles generate free radicals and cause lipid peroxidation,DNA damage, NFkappaB activation and TNF-alpha release in macrophages by Leonard SS1, Wang S, Shi X, Jordan BS, Castranova V, Dubick MA.(PubMed)
(517) The Effects of Babesiosis on Oxidative Stress and DNA Damage in Anatolian Black Goats Naturally Infected with Babesia ovis by Kucukkurt I1, Cigerci IH2, Ince S3, Kozan E4, Aytekin I5, Eryavuz A6, Fidan AF1.(PubMed)
(518) Beta-carotene and lung cancer in smokers: review of hypotheses and status of research by Goralczyk R1.(PubMed)
(519) Beta-carotene in multivitamins and the possible risk of lung cancer among smokers versus former smokers: a meta-analysis and evaluation of national brands by Tanvetyanon T1, Bepler G.(PubMed)
(520) Dietary Risk Reduction Factors for the Barrett's Esophagus-Esophageal Adenocarcinoma Continuum: A Review of the Recent Literature by Petrick JL1, Li N1, McClain KM1, Steck SE2, Gammon MD3.(PubMed)
(521) Short- and long-term beta-carotene supplementation do not influence T cell-mediated immunity in healthy elderly persons by Santos MS1, Leka LS, Ribaya-Mercado JD, Russell RM, Meydani M, Hennekens CH, Gaziano JM, Meydani SN.(PubMed)
(522) A and beta-carotene concentrations in adults with HIV/AIDS on highly active antiretroviral therapy by Kaio DJ1, Rondó PH, Souza JM, Firmino AV, Luzia LA, Segurado AA.(PubMed)
(523) Plasma antioxidant levels in chronic cholestatic liver diseases by Floreani A1, Baragiotta A, Martines D, Naccarato R, D'odorico A.(PubMed)
(524) Use of antioxidants to treat pain in chronic pancreatitis.[Article in English, Spanish by De las Heras Castaño G1, García de la Paz A, Fernández MD, Fernández Forcelledo JL.(PubMed)
(525) Functional nutraceutical profiling of wild edible and medicinal mushrooms consumed by ethnic tribes in India by Khaund P1, Joshi SR1.(PubMed)
(526)Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular cares. by Ciccone MM1, Cortese F1, Gesualdo M1, Carbonara S1, Zito A1, Ricci G1, De Pascalis F1, Scicchitano P1, Riccioni G2.(PubMed)
(527) Carotenoids and cardiovascular risk by Giordano P1, Scicchitano P, Locorotondo M, Mandurino C, Ricci G, Carbonara S, Gesualdo M, Zito A, Dachille A, Caputo P, Riccardi R, Frasso G, Lassandro G, Di Mauro A, Ciccone MM.(PubMed)
(528) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G.(PubMed)
(529) Nutritional biomarkers associated with gynecological conditions among US women with or at risk of HIV infection by Tohill BC1, Heilig CM, Klein RS, Rompalo A, Cu-Uvin S, Piwoz EG, Jamieson DJ, Duerr A.(PubMed)
(530) Low levels of plasma carotenoids are associated with an increased risk of atrial fibrillation by Karppi J1, Kurl S, Mäkikallio TH, Ronkainen K, Laukkanen JA.(PubMed)
(531)Adolescent carotenoid intake and benign breast disease by Boeke CE1, Tamimi RM2, Berkey CS3, Colditz GA4, Eliassen AH2, Malspeis S5, Willett WC6, Frazier AL7.(PubMed)
(532) Dietary carotenoids and risk of breast cancer in Chinese women by Huang JP1, Zhang M, Holman CD, Xie X.(PubMed)
(533) Effect of carotenoid β-cryptoxanthin on cellular and humoral immune response in rabbit by Ghodratizadeh S1, Kanbak G, Beyramzadeh M, Dikmen ZG, Memarzadeh S, Habibian R.(PubMed)
(534) beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages by Katsuura S1, Imamura T, Bando N, Yamanishi R.(PubMed)
(535) β-Cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice by Kobori M1, Ni Y2, Takahashi Y1, Watanabe N1, Sugiura M3, Ogawa K4, Nagashimada M5, Kaneko S6, Naito S1, Ota T2.(PubMed)
(536) Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin by Ni Y1, Nagashimada M, Zhan L, Nagata N, Kobori M, Sugiura M, Ogawa K, Kaneko S, Ota T.(PubMed)
(537) The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence by García-Closas R1, Castellsagué X, Bosch X, González CA.(PubMed)
(538) The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells by Lorenzo Y1, Azqueta A, Luna L, Bonilla F, Domínguez G, Collins AR.(PubMed)
(539) Antiproliferative activity of Cyanophora paradoxa pigments in melanoma, breast and lung cancer cells by Baudelet PH1, Gagez AL, Bérard JB, Juin C, Bridiau N, Kaas R, Thiéry V, Cadoret JP, Picot L.(PubMed)
(540) Dietary carotenoids and risk of breast cancer in Chinese women by Huang JP1, Zhang M, Holman CD, Xie X.(PubMed)
(541) Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies by Chen J1, Song Y, Zhang L.(PubMed)
(542) The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies by Etminan M1, Takkouche B, Caamaño-Isorna F.(PubMed)
(543) The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity by Linnewiel-Hermoni K1, Khanin M1, Danilenko M1, Zango G1, Amosi Y1, Levy J1, Sharoni Y2.(PubMed)
(544) Inhibitory effects of combination of lycopene and genistein on 7,12- dimethyl benz(a)anthracene-induced breast cancer in rats by Sahin K1, Tuzcu M, Sahin N, Akdemir F, Ozercan I, Bayraktar S, Kucuk O.(PubMed)
(545) Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in humanbreast cancer cell lines by Gloria NF1, Soares N, Brand C, Oliveira FL, Borojevic R, Teodoro AJ.(PubMed)
(546) Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications forlycopene intervention by Ip BC1, Wang XD2.(PubMed)
(547) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liverof rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ.(PubMed)
(548) Lycopene enhances antioxidant enzyme activities and immunity function in N-methyl-N'-nitro-N-nitrosoguanidine-enduced gastric cancer rats by Luo C1, Wu XG.(PubMed)
(549) Anti-aging effect of Blakeslea trispora powder on adult mice by Hu W1, Dai D, Li W.(PubMed)
(550) The effects of lycopene on DNA damage and oxidative stress on indomethacin-induced gastric ulcer in rats by Boyacioglu M1, Kum C2, Sekkin S2, Yalinkilinc HS2, Avci H3, Epikmen ET3, Karademir U2.(PubMed)
(551) Beneficial effect of lycopene on anti-diabetic nephropathy through diminishing inflammatory response and oxidative stress by Guo Y1, Liu Y, Wang Y.(PubMed)
(552) Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors by Pall ML1, Levine S2.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Polycystic Ovarian Syndrome
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
The Antioxidants
1. Bilirubin
Bilirubin is a prosthetic group helped to break down molecules into smaller units in releasing energy, excreted in bile and urine. It is a cellular antioxidant(511), by reverting to biliverdin, a green tetrapyrrolic bile pigment, once again when oxidized, it inhibits the effects of mutagens(512). The antioxidant showed to inhibit digestive proteases like trypsin and chymotrypsin(504), benefit heart health(505) and nonalcoholic fatty liver disease(507), reduce risk of diabetes(506). Recent studies also found that the antioxidant exhibits its anti inflammatory effects(511) against certain chronic inflammatory diseases, including psoriasis(508), chronic obstructive pulmonary disease(509), .... and enhances immunity activities(510)
2. Carotenoids
Carotenoids are organic pigments, occurring in the chloroplasts and chromoplasts(513) of plants and some photosynthetic organisms like algae and bacteria(514).
a. Beta-carotene
Beta-carotene, an organic compound classified as a terpenoid, is a strongly-coloured red-orange pigment in plants and fruits, stored in liver for the production of vitamin A. Epidemiological evidences sugested that beta-carotene neutralizes singlet oxygen before giving rise of free radicals(515) which can damage of DNA, leading to improper cell DNA replication(516)(517), causing irregual cells growth, such as cancers(518)(519)(520). The phytochemical also promotes immunity(521)(522) against foreign invasion and symptoms of chronic inflammatory disease(523)(524) and improve low-density lipoprotein cholesterol resistance to oxidation causes of cardiovascular disease related to atherosclerosis(527) through its antioxidant anti inflammatory activities(525)(526).....
b. Alpha-carotene
Alpha-carotene, one of the most abundant carotenoids in the North American diet, is a form of carotene with a β-ring at one end and an ε-ring at the other, not only protects cells from the damaging effects of free radicals(526) and enhances the immune system(528) in fighting against bacteria and virus infection and inflammation(529)(530), but also inhibits irregular cell growth(531)(532) cause of benign tumors(531) and cancers(532).
c. Beta-cryptoxanthin
Chemically Beta-cryptoxanthin is a xanthophyll which protects our cells from oxidation(538) and provides a source of vitamin A. The phytochemical showed to enhances the immune system functioning(533)(534) against infectious(537) and inflammatory diseases(535)(536) and reduces insulin resistance(536) and cancers(539)(540) risks
d. Lycopene
Lycopene is a red carotene of the carotenoids group found in tomatoes, watermelons, and grapefruits. This antioxidant is believed to be a powerful fighter against irregular growth(543), such as prostate cancer(541)(542), breast cancer(544)(545) and liver diseases(546)(547). Lycopene has many anti-aging(549) capabilities as well as enhancing immune function(548) against oxidative stress(550)(551) and inflammatory diseases(551)(552).
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References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatorydiseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(507) Serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease by Kwak MS1, Kim D, Chung GE, Kang SJ, Park MJ, Kim YJ, Yoon JH, Lee HS.(PubMed)
(508) Antioxidant status in patients with psoriasis by Nemati H, Khodarahmi R, Sadeghi M, Ebrahimi A, Rezaei M, Vaisi-Raygani A.(PubMed)
(509) Serum Bilirubin and Disease Progression in Mild Chronic Obstructive Pulmonary Disease by Apperley S, Park HY, Holmes DT, Man SF, Tashkin D, Wise RA, Connett JE, Sin DD.(PubMed)(510) Cellular-mediated immune responses in the liver tissue of patients with severe Plasmodiumfalciparum malaria by Punsawadl C, Setthapramote C, Viriyavejakul P.(PubMed)
(511) Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration by Bulmer AC1, Coombes JS, Blanchfield JT, Toth I, Fassett RG, Taylor SM.(PubMed)
(512) Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide by Mölzer C1, Huber H, Steyrer A, Ziesel GV, Wallner M, Hong HT, Blanchfield JT, Bulmer AC, Wagner KH.(PubMed)
(513) Confocal laser scanning microscopy detection of chlorophylls and carotenoids in chloroplasts and chromoplasts of tomato fruit by D'Andrea L1, Amenós M, Rodríguez-Concepción M.(PubMed)
(514) Carotenoids(Wikipedia)
(515) Lycopene Inhibits the Isomerization of β-Carotene during Quenching of Singlet Oxygen and Free Radicals by Heymann T1, Heinz P1, Glomb MA1.(PubMed)
(516) Wood smoke particles generate free radicals and cause lipid peroxidation,DNA damage, NFkappaB activation and TNF-alpha release in macrophages by Leonard SS1, Wang S, Shi X, Jordan BS, Castranova V, Dubick MA.(PubMed)
(517) The Effects of Babesiosis on Oxidative Stress and DNA Damage in Anatolian Black Goats Naturally Infected with Babesia ovis by Kucukkurt I1, Cigerci IH2, Ince S3, Kozan E4, Aytekin I5, Eryavuz A6, Fidan AF1.(PubMed)
(518) Beta-carotene and lung cancer in smokers: review of hypotheses and status of research by Goralczyk R1.(PubMed)
(519) Beta-carotene in multivitamins and the possible risk of lung cancer among smokers versus former smokers: a meta-analysis and evaluation of national brands by Tanvetyanon T1, Bepler G.(PubMed)
(520) Dietary Risk Reduction Factors for the Barrett's Esophagus-Esophageal Adenocarcinoma Continuum: A Review of the Recent Literature by Petrick JL1, Li N1, McClain KM1, Steck SE2, Gammon MD3.(PubMed)
(521) Short- and long-term beta-carotene supplementation do not influence T cell-mediated immunity in healthy elderly persons by Santos MS1, Leka LS, Ribaya-Mercado JD, Russell RM, Meydani M, Hennekens CH, Gaziano JM, Meydani SN.(PubMed)
(522) A and beta-carotene concentrations in adults with HIV/AIDS on highly active antiretroviral therapy by Kaio DJ1, Rondó PH, Souza JM, Firmino AV, Luzia LA, Segurado AA.(PubMed)
(523) Plasma antioxidant levels in chronic cholestatic liver diseases by Floreani A1, Baragiotta A, Martines D, Naccarato R, D'odorico A.(PubMed)
(524) Use of antioxidants to treat pain in chronic pancreatitis.[Article in English, Spanish by De las Heras Castaño G1, García de la Paz A, Fernández MD, Fernández Forcelledo JL.(PubMed)
(525) Functional nutraceutical profiling of wild edible and medicinal mushrooms consumed by ethnic tribes in India by Khaund P1, Joshi SR1.(PubMed)
(526)Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular cares. by Ciccone MM1, Cortese F1, Gesualdo M1, Carbonara S1, Zito A1, Ricci G1, De Pascalis F1, Scicchitano P1, Riccioni G2.(PubMed)
(527) Carotenoids and cardiovascular risk by Giordano P1, Scicchitano P, Locorotondo M, Mandurino C, Ricci G, Carbonara S, Gesualdo M, Zito A, Dachille A, Caputo P, Riccardi R, Frasso G, Lassandro G, Di Mauro A, Ciccone MM.(PubMed)
(528) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G.(PubMed)
(529) Nutritional biomarkers associated with gynecological conditions among US women with or at risk of HIV infection by Tohill BC1, Heilig CM, Klein RS, Rompalo A, Cu-Uvin S, Piwoz EG, Jamieson DJ, Duerr A.(PubMed)
(530) Low levels of plasma carotenoids are associated with an increased risk of atrial fibrillation by Karppi J1, Kurl S, Mäkikallio TH, Ronkainen K, Laukkanen JA.(PubMed)
(531)Adolescent carotenoid intake and benign breast disease by Boeke CE1, Tamimi RM2, Berkey CS3, Colditz GA4, Eliassen AH2, Malspeis S5, Willett WC6, Frazier AL7.(PubMed)
(532) Dietary carotenoids and risk of breast cancer in Chinese women by Huang JP1, Zhang M, Holman CD, Xie X.(PubMed)
(533) Effect of carotenoid β-cryptoxanthin on cellular and humoral immune response in rabbit by Ghodratizadeh S1, Kanbak G, Beyramzadeh M, Dikmen ZG, Memarzadeh S, Habibian R.(PubMed)
(534) beta-Carotene and beta-cryptoxanthin but not lutein evoke redox and immune changes in RAW264 murine macrophages by Katsuura S1, Imamura T, Bando N, Yamanishi R.(PubMed)
(535) β-Cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice by Kobori M1, Ni Y2, Takahashi Y1, Watanabe N1, Sugiura M3, Ogawa K4, Nagashimada M5, Kaneko S6, Naito S1, Ota T2.(PubMed)
(536) Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin by Ni Y1, Nagashimada M, Zhan L, Nagata N, Kobori M, Sugiura M, Ogawa K, Kaneko S, Ota T.(PubMed)
(537) The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence by García-Closas R1, Castellsagué X, Bosch X, González CA.(PubMed)
(538) The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells by Lorenzo Y1, Azqueta A, Luna L, Bonilla F, Domínguez G, Collins AR.(PubMed)
(539) Antiproliferative activity of Cyanophora paradoxa pigments in melanoma, breast and lung cancer cells by Baudelet PH1, Gagez AL, Bérard JB, Juin C, Bridiau N, Kaas R, Thiéry V, Cadoret JP, Picot L.(PubMed)
(540) Dietary carotenoids and risk of breast cancer in Chinese women by Huang JP1, Zhang M, Holman CD, Xie X.(PubMed)
(541) Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies by Chen J1, Song Y, Zhang L.(PubMed)
(542) The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies by Etminan M1, Takkouche B, Caamaño-Isorna F.(PubMed)
(543) The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity by Linnewiel-Hermoni K1, Khanin M1, Danilenko M1, Zango G1, Amosi Y1, Levy J1, Sharoni Y2.(PubMed)
(544) Inhibitory effects of combination of lycopene and genistein on 7,12- dimethyl benz(a)anthracene-induced breast cancer in rats by Sahin K1, Tuzcu M, Sahin N, Akdemir F, Ozercan I, Bayraktar S, Kucuk O.(PubMed)
(545) Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in humanbreast cancer cell lines by Gloria NF1, Soares N, Brand C, Oliveira FL, Borojevic R, Teodoro AJ.(PubMed)
(546) Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications forlycopene intervention by Ip BC1, Wang XD2.(PubMed)
(547) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liverof rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ.(PubMed)
(548) Lycopene enhances antioxidant enzyme activities and immunity function in N-methyl-N'-nitro-N-nitrosoguanidine-enduced gastric cancer rats by Luo C1, Wu XG.(PubMed)
(549) Anti-aging effect of Blakeslea trispora powder on adult mice by Hu W1, Dai D, Li W.(PubMed)
(550) The effects of lycopene on DNA damage and oxidative stress on indomethacin-induced gastric ulcer in rats by Boyacioglu M1, Kum C2, Sekkin S2, Yalinkilinc HS2, Avci H3, Epikmen ET3, Karademir U2.(PubMed)
(551) Beneficial effect of lycopene on anti-diabetic nephropathy through diminishing inflammatory response and oxidative stress by Guo Y1, Liu Y, Wang Y.(PubMed)
(552) Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors by Pall ML1, Levine S2.(PubMed)
Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica) Treatment: Individual herb: Comfrey
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Polymyalagia Arthritis (Rheumatica)
Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.
Treatments
B.2. Herbal and Traditional Chinese medicine
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
B.2.1. Individual herb
1. Comfrey
Comfrey is a perennial Plant in the genus of Symphytum, belongings to the family Boraginaceae, native to Europe, used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relief pain and swollen, treat circulation issues, reduce cholesterol, etc. According to Merck Selbstmedikation GmbH, in the searching of the literature of multiple randomized controlled trials suggested that topical comfrey treatment significantly reduce pain, inflammation and swelling of muscles and joints in degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after sports injuries and accidents, also in children aged 3 or 4 and over(194)
Dr. Staiger C said, "Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints. It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains"(195).
Furthermore, the Universidade Federal dos Vales do Jequitinhonha e Mucur study in the investigation of the efficacy of comfrey expressed the promising result in control the inflammatory process and to induce collagen deposition at 8% concentration(196).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(194) Comfrey: a clinical overview by Staiger C1.(PubMed)
(195) Comfrey root: from tradition to modern clinical trials by Staiger C1.(PubMed)
(196) In vivo wound healing effects of Symphytum officinale L. leaves extract in different topical formulations by Araújo LU1, Reis PG, Barbosa LC, Saúde-Guimarães DA, Grabe-Guimarães A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Polymyalagia Arthritis (Rheumatica)
Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.
Treatments
B.2. Herbal and Traditional Chinese medicine
Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
B.2.1. Individual herb
1. Comfrey
Comfrey is a perennial Plant in the genus of Symphytum, belongings to the family Boraginaceae, native to Europe, used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relief pain and swollen, treat circulation issues, reduce cholesterol, etc. According to Merck Selbstmedikation GmbH, in the searching of the literature of multiple randomized controlled trials suggested that topical comfrey treatment significantly reduce pain, inflammation and swelling of muscles and joints in degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after sports injuries and accidents, also in children aged 3 or 4 and over(194)
Dr. Staiger C said, "Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints. It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains"(195).
Furthermore, the Universidade Federal dos Vales do Jequitinhonha e Mucur study in the investigation of the efficacy of comfrey expressed the promising result in control the inflammatory process and to induce collagen deposition at 8% concentration(196).
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(194) Comfrey: a clinical overview by Staiger C1.(PubMed)
(195) Comfrey root: from tradition to modern clinical trials by Staiger C1.(PubMed)
(196) In vivo wound healing effects of Symphytum officinale L. leaves extract in different topical formulations by Araújo LU1, Reis PG, Barbosa LC, Saúde-Guimarães DA, Grabe-Guimarães A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM.(PubMed)
Most Common Diseases of 50Plus:The Research and Studies of Coronary heart disease - the Symptoms
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cardiovascular Disease
Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cardiovascular Disease
Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
Coronary heart disease
Coronary heart disease is defined as a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial wall, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc. affecting the small blood vessels that supply blood and oxygen to the heart. Coronary heart disease (CHD) is the leading cause of death in the United States.
The Symptoms
Some people may have the diseases without any noticeable symptoms
1. Chest pain
Chest pain raises concern for the possibility of coronary heart disease. Data collected from a multicenter Swiss clinical cohort study including 672 consecutive patients with chest pain, who had visited one of 59 family practitioners’ offices, showed that based only on history and physical examination, is a complementary tool for ruling out coronary heart disease in primary care patients complaining ofchest pain(2).
2. Emotional distress and fatigue
Evidence indicates that emotional distress has a long-term impact on morbidity and mortality in patients with coronary heart disease (CHD). In the study to investigate : (1) devise a sound and practical measure of emotional distress in CHD patients; (2) examine the relationship between emotional distress and fatiguefollowing CHD; and (3) examine changes in emotional distress as a function of cardiac rehabilitation, Dr Denollet J. at the University Hospital of Antwerp, indicated that the Global Mood Scale (GMS).
is a theoretically and psychometrically sound measure of emotional distress in CHD patients, and that this scale is sufficiently sensitive to assess change(3).
3. Dyspnoea
Dr. Fatima S, and the research team at the Ziauudin University, in the study to observe the relationship between chest pain/dyspnoea-heart rate during exertion in patients with angiographically proved Coronary artery disease compared to patients having negative Exercise Tolerance Test in a private and public sector hospital, In patients having positive ETT and referred for angiography, the chest pain-heart rate relationship correlated well with number of vessel disease. The dyspnoea-heart rate relationship was not different in the two groups(4).
4. Weakness
It may be a result of not enough blood flow to nourish the organs in the body.
5. Depression and anxiety
Dr. Rohani A, and the research team at the Yasouj University of Medical Sciences, in the investigation to determine the prevalence of anxiety and depressive symptoms in patients referred to a cardiology outpatient clinic for performing the stress test, showed that the prevalence of anxiety and depressive symptoms was estimated to be 42% and 31%, respectively, in the total chest pain population. Males with abnormal test were depressed but females experienced more anxiety symptoms. Patients with negative tests had significantly higher scores for anxiety and higher depression scores than those with positive tests. Eleven percent of the patients with positive tests were women and 23% were men(5).
7. Other symptoms
In the evaluation to examine and compare the factors associated with atypical symptoms other than chest pain in younger (<70 yr) and older (> or =70 yr) patients with first-time ACS, Dr. Hwang SY, at the Chosun University, indicated that Data were obtained from the electronic medical records of the patients (n=931) who were newly diagnosed as ACS and hospitalized from 2005 to 2006. The 7.8% (n=49) of the younger patients and 13.4% (n=41) of the older patients were found to have atypical symptoms. Older patients were more likely to complain ofindigestion or abdominal discomfort (P=0.019), nausea and/or vomiting(P=0.040), and dyspnea (P<0.001), and less likely to have chest pain (P=0.007) and pains in the arm and shoulder (P=0.018). A logistic regression analysis showed that after adjustment made for the gender and ACS type, diabetes and hyperlipidemia significantly predicted atypical symptoms in the younger patients. In the older patients, the co-morbid conditions such as stroke or chronic obstructive pulmonary disease were positive predictors(6).
8. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References(1) http://ageing.oxfordjournals.org/content/35/6/633.full
(2) http://www.ncbi.nlm.nih.gov/pubmed/20092615
(3) http://www.ncbi.nlm.nih.gov/pubmed/8475198
(4) http://www.ncbi.nlm.nih.gov/pubmed/22360019
(5) http://www.ncbi.nlm.nih.gov/pubmed/22574242
(6) http://www.ncbi.nlm.nih.gov/pubmed/19794972
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
Coronary heart disease
Coronary heart disease is defined as a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial wall, cholesterol building up in the arteries, chemicals, such as cadmium clog up arteries, etc. affecting the small blood vessels that supply blood and oxygen to the heart. Coronary heart disease (CHD) is the leading cause of death in the United States.
The Symptoms
Some people may have the diseases without any noticeable symptoms
1. Chest pain
Chest pain raises concern for the possibility of coronary heart disease. Data collected from a multicenter Swiss clinical cohort study including 672 consecutive patients with chest pain, who had visited one of 59 family practitioners’ offices, showed that based only on history and physical examination, is a complementary tool for ruling out coronary heart disease in primary care patients complaining ofchest pain(2).
2. Emotional distress and fatigue
Evidence indicates that emotional distress has a long-term impact on morbidity and mortality in patients with coronary heart disease (CHD). In the study to investigate : (1) devise a sound and practical measure of emotional distress in CHD patients; (2) examine the relationship between emotional distress and fatiguefollowing CHD; and (3) examine changes in emotional distress as a function of cardiac rehabilitation, Dr Denollet J. at the University Hospital of Antwerp, indicated that the Global Mood Scale (GMS).
is a theoretically and psychometrically sound measure of emotional distress in CHD patients, and that this scale is sufficiently sensitive to assess change(3).
3. Dyspnoea
Dr. Fatima S, and the research team at the Ziauudin University, in the study to observe the relationship between chest pain/dyspnoea-heart rate during exertion in patients with angiographically proved Coronary artery disease compared to patients having negative Exercise Tolerance Test in a private and public sector hospital, In patients having positive ETT and referred for angiography, the chest pain-heart rate relationship correlated well with number of vessel disease. The dyspnoea-heart rate relationship was not different in the two groups(4).
4. Weakness
It may be a result of not enough blood flow to nourish the organs in the body.
5. Depression and anxiety
Dr. Rohani A, and the research team at the Yasouj University of Medical Sciences, in the investigation to determine the prevalence of anxiety and depressive symptoms in patients referred to a cardiology outpatient clinic for performing the stress test, showed that the prevalence of anxiety and depressive symptoms was estimated to be 42% and 31%, respectively, in the total chest pain population. Males with abnormal test were depressed but females experienced more anxiety symptoms. Patients with negative tests had significantly higher scores for anxiety and higher depression scores than those with positive tests. Eleven percent of the patients with positive tests were women and 23% were men(5).
7. Other symptoms
In the evaluation to examine and compare the factors associated with atypical symptoms other than chest pain in younger (<70 yr) and older (> or =70 yr) patients with first-time ACS, Dr. Hwang SY, at the Chosun University, indicated that Data were obtained from the electronic medical records of the patients (n=931) who were newly diagnosed as ACS and hospitalized from 2005 to 2006. The 7.8% (n=49) of the younger patients and 13.4% (n=41) of the older patients were found to have atypical symptoms. Older patients were more likely to complain ofindigestion or abdominal discomfort (P=0.019), nausea and/or vomiting(P=0.040), and dyspnea (P<0.001), and less likely to have chest pain (P=0.007) and pains in the arm and shoulder (P=0.018). A logistic regression analysis showed that after adjustment made for the gender and ACS type, diabetes and hyperlipidemia significantly predicted atypical symptoms in the younger patients. In the older patients, the co-morbid conditions such as stroke or chronic obstructive pulmonary disease were positive predictors(6).
8. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References(1) http://ageing.oxfordjournals.org/content/35/6/633.full
(2) http://www.ncbi.nlm.nih.gov/pubmed/20092615
(3) http://www.ncbi.nlm.nih.gov/pubmed/8475198
(4) http://www.ncbi.nlm.nih.gov/pubmed/22360019
(5) http://www.ncbi.nlm.nih.gov/pubmed/22574242
(6) http://www.ncbi.nlm.nih.gov/pubmed/19794972
Obesity and Obesity's complication - The association of Obesity on Increased Uric Acid
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Uric acid, the form of ions and salts is a by product of chemical after the body breaks down purines, the substance is found in many foods, including Asparagus, Bacon, Beef, Bluefish, Bouillon, Calf tongue, Carp, Cauliflower, Chicken, Chicken soup, Codfish, Crab, Duck, Goose, etc.. High levels of uric acid in blood serum can be harmful, leading to gout and forming of kidney stones.
The association of Obesity with Increased Uric Acid
1. Acccording to the study of "Serum uric acid as an obesity-related indicator in early adolescence" by Oyama C, Takahashi T, Oyamada M, Oyamada T, Ohno T, Miyashita M, Saito S, Komatsu K, Takashina K, Takada G. (Source from Department of Pediatrics, Akita University School of Medicine, Akita, Japan. Tohoku J Exp Med. 2006 Jul;209(3):257-62), posted in PubMed, researchers found that In general, children are evaluated as obesity, when POW is equal to or more than 20% (>or= 20%). Serum uric acid levels are positively correlated with obesity-related indicators, BMI and POW, in both boys and girls. Serum uric acid levels of the subjects with high POW (>or= 20%) are significantly higher than those of the subjects with low POW (< 20%) in both boys and girls. These results suggest that serum uric acid levels are significantly increased with obesity and could be used as one of obesity-related indicators even in early adolescence.
2. In an abstract of study of "Recent trends of hyperuricemia and obesity in Japanese male adolescents, 1991 through 2002" by Ogura T, Matsuura K, Matsumoto Y, Mimura Y, Kishida M, Otsuka F, Tobe K. (Source from Health and Medical Center, Okayama University, Okayama, Japan. Metabolism. 2004 Apr;53(4):448-53), posted in PubMed, researchers found rhat Hyperuricemia was related to the presence of other risk factors, including hypercholesterolemia, liver function abnormality, and hypertension. The frequencies of such abnormalities were higher than euuricemic subjects and this trend was notable in the most recent students enrolled from 1999 through 2002. Hyperuricemia was even found in the group of non-obese male adolescents. Taking into consideration that hyperuricemia is associated with a high prevalence of lifestyle-related diseases in adults, it is of great importance to prevent hyperuricemia at the early stage in Japanese adolescents.
3. In a study of "[Uric acid nephrolithiasis]", [Article in French], by Dussol B.(Source from Centre de néphrologie et de transplantation rénale, hôpital de la Conception, 13385 Marseille Cedex 05. bertrand.dussol@ap-hm, Rev Prat. 2011 Mar;61(3):389-92), posted in PubMed, researcher indicated that Its frequency will increase in the next decades because of the ageing and the increasing prevalence of obesity and type 2 diabetes mellitus. The pathophysiologic defect is an excessively acidic urine pH rather than hyperuricosuria. Undissociated uric acid is poorly soluble in acidic urines (pH < 5.5) but solubility increases when sodium urate forms at higher pH. Insulin resistance may contribute to the development of acidic urine because of higher net acid excretion. Because uric acid kidney stones are radiolucent, diagnosis is based on echography and tomodensitometry. Medical management strategies focus primarily on alkali treatment and/or decreasing hyper-uricosuria.
4. According to a study of "Uric acid nephrolithiasis" by Liebman SE, Taylor JG, Bushinsky DA. (Source from University of Rochester School of Medicine and Dentistry, Nephrology Division, Strong Memorial Hospital, Rochester, NY 14642, USA. scott_liebman@urmc.rochester.edu, Curr Rheumatol Rep. 2007 Jun;9(3):251-7.), posted in PubMed, researchers found that Uric acidnephrolithiasis is typically found in individuals with a low urine pH and a normal concentration of urinary uric acid. Patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or the complete metabolic syndrome. The unifying renal tubular abnormality of these disorders appears to be the excretion of abnormally acidic urine. This article focuses on the relationship of these disorders to the development of uric acid stones.
5. According to a study of "Relation of uric acid with components of metabolic syndrome before and after Roux-en-Y gastric bypass in morbidly obese subjects" by Serpa Neto A, Rossi FM, Valle LG, Teixeira GK, Rossi M. (Source from Division of Clinical and Surgical Treatment of Obesity, Faculdade de Medicina do ABC, Santo André, SP, Brazil. aryserpa@terra.com.br, Arq Bras Endocrinol Metabol. 2011 Feb;55(1):38-45.), posted in PubMed, researchers indicated in abstract that Concentrations of uric acid were associated with the prevalence of metabolic abnormalities in this sample of morbidly obese patients. Also, weight loss after RYGBP can reduce uric acid levels and the prevalence of hyperuricemia.
6. Etc.
Treatments of Obesity and Increased Uric Acid
1. According to the abstract of the study of "Obesity and urolithiasis" by Asplin JR. (Source from Litholink Corporation, Chicago, IL 60612, USA. jasplin@litholink.com, Adv Chronic Kidney Dis. 2009 Jan;16(1):11-20), posted in PubMed, researchers stated that Obesity can increase stone risk in multiple ways. Excess nutritional intake increases traffic of lithogenic substances such as calcium, oxalate, and uric acid. Metabolic syndrome, commonly associated withobesity, alters renal acid-base metabolism, resulting in a lower urine pH andincreased risk of uric acid stone disease......, Certainly, the many health risks ofobesity, including urolithiasis, necessitate weight loss, but recognition of the potential complications of such therapies is required to prevent induction of new and equally severe medical problems. The optimal approach to weight control that minimizes stone risk needs to be determined.
2. In a study of "Body size and 24-hour urine composition" by Taylor EN, Curhan GC. (Source from Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. entaylor@partners.org, Am J Kidney Dis. 2006 Dec;48(6):905-15), posted in PubMed, researchers filed the conclusion of Positive associations between BMI and urinary calcium excretion likely are due to differences in animal protein and sodium intake. The greater incidence of kidney stones in the obese may be due to an increase in uric acid nephrolithiasis.
3. In abstract of the study of "Benefits of sustained moderate weight loss inobesity" by Pasanisi F, Contaldo F, de Simone G, Mancini M. (Source from Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy. pasanisi@unina.itm Nutr Metab Cardiovasc Dis. 2001 Dec;11(6):401-6.), posted in PubMed, researchers found that a large number of obese patients may be sensitive to a modest weight loss even without the achievement of ideal body weight. Sustained moderate weight loss by itself is definitely beneficial in obesity(especially "malignant" and "morbid" obesity), but also in diabetes, hypertension, hyperlipidaemia, cardiorespiratory diseases and other chronic degenerative diseases associated with any degree of excess body fat.
4. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Uric acid, the form of ions and salts is a by product of chemical after the body breaks down purines, the substance is found in many foods, including Asparagus, Bacon, Beef, Bluefish, Bouillon, Calf tongue, Carp, Cauliflower, Chicken, Chicken soup, Codfish, Crab, Duck, Goose, etc.. High levels of uric acid in blood serum can be harmful, leading to gout and forming of kidney stones.
The association of Obesity with Increased Uric Acid
1. Acccording to the study of "Serum uric acid as an obesity-related indicator in early adolescence" by Oyama C, Takahashi T, Oyamada M, Oyamada T, Ohno T, Miyashita M, Saito S, Komatsu K, Takashina K, Takada G. (Source from Department of Pediatrics, Akita University School of Medicine, Akita, Japan. Tohoku J Exp Med. 2006 Jul;209(3):257-62), posted in PubMed, researchers found that In general, children are evaluated as obesity, when POW is equal to or more than 20% (>or= 20%). Serum uric acid levels are positively correlated with obesity-related indicators, BMI and POW, in both boys and girls. Serum uric acid levels of the subjects with high POW (>or= 20%) are significantly higher than those of the subjects with low POW (< 20%) in both boys and girls. These results suggest that serum uric acid levels are significantly increased with obesity and could be used as one of obesity-related indicators even in early adolescence.
2. In an abstract of study of "Recent trends of hyperuricemia and obesity in Japanese male adolescents, 1991 through 2002" by Ogura T, Matsuura K, Matsumoto Y, Mimura Y, Kishida M, Otsuka F, Tobe K. (Source from Health and Medical Center, Okayama University, Okayama, Japan. Metabolism. 2004 Apr;53(4):448-53), posted in PubMed, researchers found rhat Hyperuricemia was related to the presence of other risk factors, including hypercholesterolemia, liver function abnormality, and hypertension. The frequencies of such abnormalities were higher than euuricemic subjects and this trend was notable in the most recent students enrolled from 1999 through 2002. Hyperuricemia was even found in the group of non-obese male adolescents. Taking into consideration that hyperuricemia is associated with a high prevalence of lifestyle-related diseases in adults, it is of great importance to prevent hyperuricemia at the early stage in Japanese adolescents.
3. In a study of "[Uric acid nephrolithiasis]", [Article in French], by Dussol B.(Source from Centre de néphrologie et de transplantation rénale, hôpital de la Conception, 13385 Marseille Cedex 05. bertrand.dussol@ap-hm, Rev Prat. 2011 Mar;61(3):389-92), posted in PubMed, researcher indicated that Its frequency will increase in the next decades because of the ageing and the increasing prevalence of obesity and type 2 diabetes mellitus. The pathophysiologic defect is an excessively acidic urine pH rather than hyperuricosuria. Undissociated uric acid is poorly soluble in acidic urines (pH < 5.5) but solubility increases when sodium urate forms at higher pH. Insulin resistance may contribute to the development of acidic urine because of higher net acid excretion. Because uric acid kidney stones are radiolucent, diagnosis is based on echography and tomodensitometry. Medical management strategies focus primarily on alkali treatment and/or decreasing hyper-uricosuria.
4. According to a study of "Uric acid nephrolithiasis" by Liebman SE, Taylor JG, Bushinsky DA. (Source from University of Rochester School of Medicine and Dentistry, Nephrology Division, Strong Memorial Hospital, Rochester, NY 14642, USA. scott_liebman@urmc.rochester.edu, Curr Rheumatol Rep. 2007 Jun;9(3):251-7.), posted in PubMed, researchers found that Uric acidnephrolithiasis is typically found in individuals with a low urine pH and a normal concentration of urinary uric acid. Patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or the complete metabolic syndrome. The unifying renal tubular abnormality of these disorders appears to be the excretion of abnormally acidic urine. This article focuses on the relationship of these disorders to the development of uric acid stones.
5. According to a study of "Relation of uric acid with components of metabolic syndrome before and after Roux-en-Y gastric bypass in morbidly obese subjects" by Serpa Neto A, Rossi FM, Valle LG, Teixeira GK, Rossi M. (Source from Division of Clinical and Surgical Treatment of Obesity, Faculdade de Medicina do ABC, Santo André, SP, Brazil. aryserpa@terra.com.br, Arq Bras Endocrinol Metabol. 2011 Feb;55(1):38-45.), posted in PubMed, researchers indicated in abstract that Concentrations of uric acid were associated with the prevalence of metabolic abnormalities in this sample of morbidly obese patients. Also, weight loss after RYGBP can reduce uric acid levels and the prevalence of hyperuricemia.
6. Etc.
Treatments of Obesity and Increased Uric Acid
1. According to the abstract of the study of "Obesity and urolithiasis" by Asplin JR. (Source from Litholink Corporation, Chicago, IL 60612, USA. jasplin@litholink.com, Adv Chronic Kidney Dis. 2009 Jan;16(1):11-20), posted in PubMed, researchers stated that Obesity can increase stone risk in multiple ways. Excess nutritional intake increases traffic of lithogenic substances such as calcium, oxalate, and uric acid. Metabolic syndrome, commonly associated withobesity, alters renal acid-base metabolism, resulting in a lower urine pH andincreased risk of uric acid stone disease......, Certainly, the many health risks ofobesity, including urolithiasis, necessitate weight loss, but recognition of the potential complications of such therapies is required to prevent induction of new and equally severe medical problems. The optimal approach to weight control that minimizes stone risk needs to be determined.
2. In a study of "Body size and 24-hour urine composition" by Taylor EN, Curhan GC. (Source from Renal Division and Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. entaylor@partners.org, Am J Kidney Dis. 2006 Dec;48(6):905-15), posted in PubMed, researchers filed the conclusion of Positive associations between BMI and urinary calcium excretion likely are due to differences in animal protein and sodium intake. The greater incidence of kidney stones in the obese may be due to an increase in uric acid nephrolithiasis.
3. In abstract of the study of "Benefits of sustained moderate weight loss inobesity" by Pasanisi F, Contaldo F, de Simone G, Mancini M. (Source from Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy. pasanisi@unina.itm Nutr Metab Cardiovasc Dis. 2001 Dec;11(6):401-6.), posted in PubMed, researchers found that a large number of obese patients may be sensitive to a modest weight loss even without the achievement of ideal body weight. Sustained moderate weight loss by itself is definitely beneficial in obesity(especially "malignant" and "morbid" obesity), but also in diabetes, hypertension, hyperlipidaemia, cardiorespiratory diseases and other chronic degenerative diseases associated with any degree of excess body fat.
4. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
The Obesity' Research and Studies - Effect of weight reduction on cardiovascular risk factors
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Overweight or obese is aleady proven to be associated with an increased risk for the development of non-insulin-dependent diabetes mellitus, hypertension, and cardiovascular disease, etc. In the study of the effect of a low calorie diet in combination with oral supplementation by vitamins, minerals, probiotics and human chorionic gonadotropin (hCG, 125-180 IUs) on the body composition, lipid profile and CD34-positive cells in circulation. During this dieting program, the following parameters were assessed weekly for all participants: fat free mass, body fat, BMI, extracellular/intracellular water, total body water and basal metabolic rate. For part of participants blood chemistry parameters and circulating CD34-positive cells were determined before and after dieting. The data indicated that the treatments not only reduced body fat mass and total mass but also improved the lipid profile. The changes in body composition correlated with the level of lipoproteins responsible for the increased cardiovascular risk factors. These changes in body composition and lipid profile parameters coincided with the improvement of circulatory progenitor cell numbers(1)
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1) "Effect of weight reduction on cardiovascular risk factors and CD34-positive cells in circulation" by Mikirova NA, Casciari JJ, Hunninghake RE, Beezley MM.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Overweight or obese is aleady proven to be associated with an increased risk for the development of non-insulin-dependent diabetes mellitus, hypertension, and cardiovascular disease, etc. In the study of the effect of a low calorie diet in combination with oral supplementation by vitamins, minerals, probiotics and human chorionic gonadotropin (hCG, 125-180 IUs) on the body composition, lipid profile and CD34-positive cells in circulation. During this dieting program, the following parameters were assessed weekly for all participants: fat free mass, body fat, BMI, extracellular/intracellular water, total body water and basal metabolic rate. For part of participants blood chemistry parameters and circulating CD34-positive cells were determined before and after dieting. The data indicated that the treatments not only reduced body fat mass and total mass but also improved the lipid profile. The changes in body composition correlated with the level of lipoproteins responsible for the increased cardiovascular risk factors. These changes in body composition and lipid profile parameters coincided with the improvement of circulatory progenitor cell numbers(1)
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1) "Effect of weight reduction on cardiovascular risk factors and CD34-positive cells in circulation" by Mikirova NA, Casciari JJ, Hunninghake RE, Beezley MM.
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