Medical Advisor Journals

Monday, June 13, 2016

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Weight Loss Vitamin C

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

The Treatments

In Weight Loss Perspective
Weight loss(733)(734) for obese patients is one of most vital factor to reduce PCOs symptoms(735)(737) and risk of PCOs complications(736)(737). Some researchers found that 5-10% of weight low will improve PCOs features(737) by 25%, including pregnancy(738). How can you lose weight and maintain healthybody for a healthy conception?

The Weight Loss Vitamins C

Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin, found in fresh fruits, berries and green vegetables. It is best known for its free radical scavengers activity and regenerating oxidized vitamin E for immune support.

Vitamin C deficiency and incidence of obesity
Vitamin C and other nutrients deficiency not only are associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808). According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin Cstatus(810)

Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin Cand indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase of Citrus spp. fruits of Spanish origin, grapefruit, containing higher contents of phytochemicals, vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid, in the study of whether the vitamin would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, indicated that addition of vitamin C in diet influences the reduction in body weight gain and food efficiency ratio, and increases in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814).

Taking altogether, deficiency of vitamin C and other nutrients are associated to increase risk of obese incidence. Vitamin C may be effective in induced weight loss for obese subjects due to its positive interaction in inhibiting oxidative stress causes of endothelial dysfunction. Daily ingestion of high-dose vitamin C may be considered safe, but in rare incidence, overdoses in a prolonged period of time, may cause intra-renal oxalate crystal deposition, a fatal nephrotoxicity(815)(816).

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The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

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References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M1.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M1, Kravos NA1, Pfeifer M1, Kocjan T1, Janez A1.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG1, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V1, Vansteelandt S2, T'Sjoen G3, Gerris J4, Somers S4, Vercruysse L4, De Sutter P4.(PubMed)
(807) High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice by Tranberg B1, Hansen AK, Lykkesfeldt J.(PubMed)
(808) Zinc, iron and vitamins A, C and e are associated with obesity, inflammation, lipid profile and insulin resistance in mexican school-aged children by García OP1, Ronquillo D, del Carmen Caamaño M, Martínez G, Camacho M, López V, Rosado JL.(PubMed)
(809) Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: results from a cross-sectional study by García OP1, Ronquillo D, Caamaño Mdel C, Camacho M, Long KZ, Rosado JL.(PubMed)
(810) Strategies for healthy weight loss: from vitamin C to the glycemic response by Johnston CS.(PubMed)
(811) Mechanisms of endothelial dysfunction in obesity(Science direct)
(812) Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C. by Perticone F1, Ceravolo R, Candigliota M, Ventura G, Iacopino S, Sinopoli F, Mattioli PL.(PubMed)
(813) Phytochemistry and biological activity of Spanish Citrus fruits by Gironés-Vilaplana A1, Moreno DA, García-Viguera C.(PubMed)
(814) Anti-obesity effects of chitosan and psyllium husk with L-ascorbic acid in guinea pigs by Jun SC1, Jung EY, Hong YH, Park Y, Kang Dh, Chang UJ, Suh HJ.(PubMed)
(815) Fatal vitamin C-associated acute renal failure by McHugh GJ, Graber ML, Freebairn RC.(PubMed)
(816) Ascorbic acid overdosing: a risk factor for calcium oxalate nephrolithiasis by Urivetzky M, Kessaris D, Smith AD.(PubMed)

Food therapy - Vegetables - Carrots (Daucus carota)

Carrot can grow to 3ft tall. It is root vegetable with orange color normally, a sub spices of Daucus carota, belongs to the family Apiaceae, native to Asian and Europe.

Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C 13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium
21. Etc.

Health benefits
A. Health Benefits according to studies
1. Colon cancer
Carrot juice has exerted the property in reducing the risk of colon cancer, according to the study of "Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans" by Schnäbele K, Briviba K, Bub A, Roser S, Pool-Zobel BL, Rechkemmer G.(a)

2. Cardiovascular health
Drinking carrot juice can enhance the cardiovascular health as it increases the total antioxidant status and decreases the lipid peroxidation, according to the study of "Drinking carrot juice increases total antioxidant status and decreases lipid peroxidation in adults" by Potter AS, Foroudi S, Stamatikos A, Patil BS, Deyhim F.(b)

3. LeukemiaCarrot juice extract with has exerted the properties of induced apoptosis and inhibited progression through the cell cycle in the treatment of leukemia, according to the study of "Bioactive Chemicals from Carrot (Daucus carota) Juice Extracts for the Treatment of Leukemia" by Zaini R, Clench MR, Le Maitre CL.(c)

4. Purple carrot juice
Purple carrot juice (usually orange inside) has demonstrated the antioxidant and anti-inflammatory properties in improving glucose tolerance as well as cardiovascular and hepatic structure and function, according to the study of "Comparison of purple carrot juice and β-carotene in a high-carbohydrate, high-fat diet-fed rat model of the metabolic syndrome" by Poudyal H, Panchal S, Brown L.(d)

5. Oxidative DNA damage
Carot juice may have a possible preventive effects in disease causation and progression caused by Oxidative DNA damage due to its antioxidant properties, according to the study of "Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies" by Møller P, Loft S.(e)

6. Etc.

B. Health Benefits according to the concentration
1. Antioxidant
Carrot contains high amount of antioxidants Vitamin A, it not only improves the immune system in fighting against invasion of foreign substances and regulates the normal cell growth, thus decreasing the risk of cancer and tumor, according to the study of "Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells" by Zhang X, Zhao WE, Hu L, Zhao L, Huang J.(1), but also protects vision health as it helps the eyes to adjust to light changes by preventing night blind blindness by increasing the adaptability of the human eye to bright light and darkness, according to the study of "Culture of highly differentiated humanretinal pigment epithelium for analysis of the polarized uptake, processing, and secretion of retinoids" by Hu J, Bok D.(2)

2. Coagulation and wrinkles
Carrot contains a measurable amount of vitamin K of that not only enhances the under layer of skin against skin aging, according to the study of "Vitamin K shows potential in the fight against wrinkle" katie Bird (3)by but also improve coagulation caused by bleeding of wound, acccording to the study of "Vitamin K-dependent coagulation factors deficiency" by Brenner B, Kuperman AA, Watzka M, Oldenburg J.(4)

3. Vitamin C
Vitamin C not only has been best known for its function in relieve the symptoms of common cold, according to the study of "Examining the evidence for the use ofvitamin C in the prophylaxis and treatment of the common cold" by Heimer KA, Hart AM, Martin LG, Rubio-Wallace S..(5) but also lowers the risk of upperrespiratory tract infection, according to the study of "Dietary intake and supplement use of vitamins C and e and upper respiratory tract infection" by Fondell E, Bälter O, Rothman KJ, Bälter K.(6)

4. Etc.

C. Other health Benefits
1. Diabetes

carrot contains high amount of fiber which helps to release the glucose slowly into blood stream as it has an inverse relationship with the prevalence of the metabolic syndrome and may contribute to both the prevention and treatment of type 2diabetes mellitu, according to the study of "[Dietary fibers: current trends and health benefits in the metabolic syndrome and type 2 diabetes].[Article in Portuguese]" by Mello VD, Laaksonen DE(7)
2. Colon cancer
The polyacetylene falcarinol, isolated from carrot may have the potential in benefiting colon cancer ,according to the study of "Biphasic effect of falcarinolon caco-2 cell proliferation, DNA damage, and apoptosis" by Young JF, Duthie SJ, Milne L, Christensen LP, Duthie GG, Bestwick CS.(8)

3. Hypertension
Potassium rich of carrot not only helps to maintain the of the levels of sodium but also reduces the rick of high blood pressure due to it diuretic effects, according to the study of "Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension' by Heran BS, Chen JM, Wang JJ, Wright JM.(9)
4. Obesity
Since it contains high amount of fiber, it makes the stomach feeling fullness longer, thus reducing the risk food craving, according to the study of "The role ofdietary fiber in the development and treatment of childhood obesity" by Kimm SY.(10)

4. Etc.

Side Effects
1. Over consumption of carrots can cause a benign condition of the skin turns orange.
2. Since it is a root vegetable, people with weakened kidney should consult with their doctor before consuming.
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/18254985
(b) http://www.ncbi.nlm.nih.gov/pubmed/21943297
(c) http://www.ncbi.nlm.nih.gov/pubmed/21864090
(d) http://www.ncbi.nlm.nih.gov/pubmed/20619064
(e) http://www.ncbi.nlm.nih.gov/pubmed/12144999
(1) http://www.ncbi.nlm.nih.gov/pubmed/21620794
(2) http://www.ncbi.nlm.nih.gov/pubmed/20552421
(3) http://www.nutraingredients.com/Research/Vitamin-K-shows-potential-in-the-fight-against-wrinkles(4) http://www.ncbi.nlm.nih.gov/pubmed/19598072
(5) http://www.ncbi.nlm.nih.gov/pubmed/19432914
(6) http://www.ncbi.nlm.nih.gov/pubmed/21917705
(7) http://www.ncbi.nlm.nih.gov/pubmed/19768242
(8) http://www.ncbi.nlm.nih.gov/pubmed/17263451
(9) http://www.ncbi.nlm.nih.gov/pubmed/20091662
(10) http://www.ncbi.nlm.nih.gov/pubmed/7494672

The #CurableSmoothie of Blueberry, Tomato and Pineapple for Reduced Risk and Treatment of Membranous Glomerulonephritis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Membranous glomerulonephritis
Yield: 2 servings (about 8 ounces each)
1/ 2 cup tomato
1/2 cup pineapple
1 1/2 cups blueberry juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Membranous glomerulonephritis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Membranous glomerulonephritis is a slowly progressive kidney disease caused by the thickening of part of the glomerular basement membrane as a result of autoimmune injury(1) probably caused by expression of anti-aldose reductase (AR) and anti-manganese superoxide dismutase (SOD2) IgG(6), affecting mostly Caucasian patients between ages of 30 and 50 years.
Recent study led by renowned institutions suggested that Resveratrol found abundantly may consist strong anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy(2), through attenuated renal Eathological changes in db/db mice model(3).

Ferulic Acid found in tomato may be used as phytochemicals derived from dietary components to combat human diseases, including membranous glomerulonephritis(4). According to the Taipei Medical University, the antioxidant also an Derived Polyphenol from Dang Qui, inhibited the progression of membranous Nephropathy in a Mouse Model, through involved the regulation of oxidative stresses, angiogenic and antiangiogenic factors, and attenuation of Th2 immune response(4)
Melatonin, boosted intake of pineapple, in animal model, exhibited anti expression of anti-inflammatory cytokines (interleukin 10), production of reactive oxygen species and induced apoptotic TUNEL-positive apoptotic cells in the kidney through amelioration of proteinuria and glomerular lesions,...of membranous glomerulonephritis((5).

The smoothie of Blueberry, Tomato and Pineapple may hold a key in further studies in production of effective natural ingredients for prevention and treatment of any type of Membranous glomerulonephritis without inducing adverse effects.

People who are at increased risk of any of Membranous glomerulonephritis, due to family history, weaken immunity... should drink at least one cup daily. People with Membranous glomerulonephritis, should drink no more than 4 servings daily, depending to the digestive toleration.

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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Rerences
(1) Biologics for the treatment of autoimmune renal diseases by Holdsworth SR1,2, Gan PY1, Kitching AR1,2.(PubMed)
(2) Resby veratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy Wu CC1, Huang YS2, Chen JS3, Huang CF4, Su SL5, Lu KC6, Lin YF7, Chu P3, Lin SH3, Sytwu HK8.(PubMed)
(3) Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway by Kitada M1, Kume S, Imaizumi N, Koya D.(PubMed)
(4)Ferulic Acid, an Angelica sinensis-Derived Polyphenol, Slows the Progression of Membranous Nephropathy in a Mouse Model by Cheng CW1, Chang WL, Chang LC, Wu CC, Lin YF, Chen JS.(PubMed)(5) Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy by Wu CC1, Lu KC, Lin GJ, Hsieh HY, Chu P, Lin SH, Sytwu HK.(PubMed)
(6) Autoimmunity in membranous nephropathy targets aldose reductase and SOD2 by Prunotto M1, Carnevali ML, Candiano G, Murtas C, Bruschi M, Corradini E, Trivelli A, Magnasco A, Petretto A, Santucci L, Mattei S, Gatti R,Scolari F, Kador P, Allegri L, Ghiggeri GM.(PubMed)

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs – Ban Xia (Rhizoma Pinelliae Ternatae)

Ingredients
1. β-sitosterol
2. Choline
3. Daucosterol
4. 3,4-dihydroxybenzaldehyde
5. Coniine
5. Protoanemonin
6. 1-ephedrine hydrochloride
7. Guanosine
8. Homogentisic acid
9. Etc.

Health Benefits
1. Anti-obesity
Pinellia ternata water extract (PE) has significantly increased the expression of both UCP1 mRNA in brown adipose tissue (BAT) (p<0.001) and PPARalpha and PGC1alpha mRNA in white visceral adipose tissue (WAT) (p<0.05 and p<0.001, respectively) that may br suggested to be used affect anti-obesity through thermogenesis and fatty acid oxidation, according to the study of “Anti-obesity effect of Pinellia ternata extract in Zucker rats” by Kim YJ, Shin YO, Ha YW, Lee S, Oh JK, Kim YS.(1).

2. Neuroprotective effect
Chukmesundan (CMSD), composed of the following 8 medicinal herbs, including Ban Xia(Pinellia ternata BREIT) has shown to protect primary cultured neurons from N-methyl-D: -aspartate receptor-mediated glutamate toxicity. It was in vivo evidenced that CMSD protects neurons against ischemia-induced cell death, according to the study of “Neuroprotective effect of a chuk-me-sun-dan on neurons from ischemic damage and neuronal cell toxicity” by Chung TW, Koo BS, Choi EG, Kim MG, Lee IS, Kim CH.(2).

3. Anti-microbial effects
Pinelloside isolated from the air-dried tubers of Ban Xia (Pinellia ternata (Thunb)Breit) have shown the inhibitory effects to the growth of Bacillus subtilis, Staphylococcus aureus, Aspergillus niger and Candida albicans, with minimum inhibitory concentrations (MICs) of 20, 50, 30 and 10 microg/ml, respectively, according to the study of “Pinelloside, an antimicrobial cerebroside from Pinellia ternata” by Chen JH, Cui GY, Liu JY, Tan RX.(3).

4. Nasal influenza HA vaccine
Pinellic acid of the tuber of Pinellia ternata Breitenbach (1 microg) has enhanced antiviral IgA antibody (Ab) titers 5.2- and 2.5-fold in nasal and bronchoalveolar washes in mice, as it may provide a safe and potent oral adjuvant for nasal influenza HA vaccine, according to the study of “Pinellic acid from the tuber of Pinellia ternata Breitenbach as an effective oral adjuvant for nasal influenza vaccine” by Nagai T, Kiyohara H, Munakata K, Shirahata T, Sunazuka T, Harigaya Y, Yamada H.(4).

5. Anti-allergic activity
pinellic acid of Pinellia ternata Breitenbach found in “Sho-seiryu-to (SST, Xiao-Qing-Long-Tang in Chinese) has reduced the OVA-specific IgE antibody titer in bronchoalveolar lavage (BAL) fluids at 7 days after orally administered at 0.5 g/kg/day from day 1 to 6 days of OVA (ovalbumin) inhalatiom. CD4(+) T cells obtained from the mouse lung produced more interleukin (IL)-4 and IL-5 but less interferon (IFN)-gamma than T cells from nonsensitized control animals, accoring to the study of “Anti-allergic activity of a Kampo (Japanese herbal) medicine “Sho-seiryu-to (Xiao-Qing-Long-Tang)” on airway inflammation in a mouse model” by Nagai T, Arai Y, Emori M, Nunome SY, Yabe T, Takeda T, Yamada H.(5).

6. Antidepressant effects
Banxia Houpu Decoction, a traditional Chinese medicine, including Ban Xia has shown to possess an antidepressant activity that was close to that of Prozac in ethanol extract, according to the study of “Antidepressant effects of Banxia Houpu decoction, a traditional Chinese medicinal empirical formula” by Luo L, Nong Wang J, Kong LD, Jiang QG, Tan RX.(6).

7. Etc.

Side Effects
1. Since the herb is toxic, Do not use the lone herb, but with other antitoxicity herbs such as mung bean, fang feng, gan cao.
2. Do not use if you are pregnant or breast feeding, or only with the permission of the related field specialist.
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16755034
(2) http://www.ncbi.nlm.nih.gov/pubmed/16474991
(3) http://www.ncbi.nlm.nih.gov/pubmed/14559289
(4) http://www.ncbi.nlm.nih.gov/pubmed/12349955
(5) http://www.ncbi.nlm.nih.gov/pubmed/15313433

Most Common Diseases of 50Plus:The Research and Studies of Ischemic heart disease - The Diagnosis and tests

Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).

Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

Ischemic heart disease

Ischemic heart disease is defined as a condition of reduced blood supply of the heart muscle, as a result of coronary artery disease caused by plague building up in the arteries.

The Diagnosis and tests

Diagnosis of ischemic heart disease are depending to the nature symptoms for discovering the disease in its early stages to prevent a heart attack from occurring
1. Electrocardiogram or electrocardiography (ECG)
Electrocardiogram or electrocardiography (ECG) is the test to diagnose the heart conditions by measuring the electrical activity of the heart and highly recommendation for patients showing symptoms of severe chest pain. An abnormal patterns on the EKG may be an indication of Ischemia. In some cases, exercise testing, an exercise ECG test or 'stress test' as ECG recording is taken while you are exercising to induce the symptoms of chest pain in finding the causes.

2. X ray
X ray may be necessary to rule out other causes of the symptoms.

3. Blood tests
The aim of the blood test is to monitor the activity of the heart, including cardiac enzyme tests to test for the damage of heart muscle.
4. Echocardiogram (echo)

Echocardiogram (echo) provide your doctor an image of your heart using sound waves by identifying the overall function of your heart, including the structure, thickness, movement of each heart valve, etc.
Some researchers indicated that Exercise testing, whether by echocardiographyor ECG, is more useful at excluding CAD than confirming it. Clinicians have concentrated on individualising the treatment of CAD, but there is great scope for individualising the diagnosis of CAD using exercise testing(16).

5. Coronary angiography
The aim of the test is to provide information of providing information of your heart functioning and to identify the narrowing and blockage of the coronary arteries.
6. Radionuclide stress test
The aim of the test is to identify whether the blockage in a coronary artery results in diminished blood flow to a part of the cardiac muscle.
7. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(16) http://www.ncbi.nlm.nih.gov/pubmed/22512607

The Obesity's Article: Weight Loss - The Tips

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

For a healthy person weight loss is simple: burn more calories than you consume. The healthiest weight is determine by height to weight ratio or Body Mass Index (BMI) and the amount of fat in your body. Unfortunately over 60% of the North American population is considered to be overweight, according to the BMI index.

Together with a healthy diet and consuming more of fruits, vegetables and meat and dairy foods that are low in saturated and trans fat would help you to lose weight and keep it off longer. Be sure to talk to your doctor before you would like to start any weight loss program.
Here are some common sense approaches that might help you to lose weight:

1. Don't skip your breakfast
Skipping meals will only cause you to eat more in the next meal. After a long period of hunger, your stomach triggers the brain to release more chemicals that ask you to eat more (more than 2 meals combine) in the next meal.

2. Follow the BMI index
According to the National Institution of Health, the definition of healthy weight is a BMI of 24 or less. Men and Women with a BMI of 25-30 are considered to beoverweight. BMI is reliable for people from 19-70 years of age. Study reveals that for people over 64 years of age, the risk of dying from heart disease does not go up with a BMI between 25-27. A BMI over 28 seems to increase risk of heart disease.

3. Slowly and Surely
Change your lifestyle habits slowly. Each day replace some of the saturated and trans fat foods
with healthier foods.
Start Exercising gradually. Walk 10 minutes a day for a few days then 15 minutes, 30 minutes. Keep going until you work your way up to doing a supervised exercise program. Be happy if you lose 2 to 3 Lbs a week.

4. Stay Moderately active
Sitting in front of the computer or television all day will increase the risk of arthritis, type II diabetes, obesity, heart diseases, and depression.

5. Shopping parking
Parking your car at the far end of the parking lot will help you to burn more calories. If you calculate the calories which you burn from all the trips that you take such as mall shopping, grocery shopping, working, picking up the kid from school, you will be surprised. Each mile will burn somewhere around 125 calories.

6. Moderate intake of alcohol
Moderate drinking of alcohol beverages containing no fat, no cholesterol, and very little sodium and is often associated with weight loss in women. Moderate consumption of alcohol is associated with better health and longer life. Drinking a cup of red wine for women and two cups for men daily will help increase blood circulation and decrease risk of heart attack.

7. Study shows that eating chicken soup with rice and drinking water together before meal will help to curb your appetite.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer