Monday, June 13, 2016

Herbal therapy: Popular Herbal Goat's Rue

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                     Goat's rue 

Goat's rue is is an herbaceous plant, in the genus Galega, belonging to the family Fabaceae, native to to the Middle East. The herb has been used in traditional medicine to increase milk flow, treat diabetes

Health benefits
1. Anti-bacterial activity
In the testing of Alcoholic extracts of Goat's Rue (Galega officinalis L.; Papilionaceae) on Gram +ve and Gram -ve bacteria found that Ethanolic (60%) extract exhibited significant inhibition on growth of both Gram +ve and Gram -ve bacteria, according to "Anti-bacterial activity of Galega officinalis L. (Goat's Rue)" by Pundarikakshudu K, Patel JK, Bodar MS, Deans SG.(1)

2. Weight Loss
In the pharmacological investigations in mice of an ethanolic extract of a powdered mixture of equal proportions of G. officinalis, Cressa cretica, Mangifera indica and Syzygium jambolanum, found that together with its established hypoglycaemic effects, galega has a novel weight reducing action that, in normal mice, is largely independent of a reduction in food intake. The mechanism of the weight reducing action of galega is unclear but involves loss of body fat, according to "Novel weight-reducing activity of Galega officinalis in mice" by Palit P, Furman BL, Gray AI.(2)

3. Platelet aggregation
In the testing of the inhibiting and disaggregating effect of desalted and fractionated herbal extract of Galega officinalis L. on platelet aggregation in vitro, found that at a concentration of 40 micrograms/ml PRP the fraction inhibits the initiation of platelet aggregation by collagen and at 50 micrograms/ml PRP inhibits the initiation of aggregation by thrombin. At a concentration of 65 micrograms/ml PRP the fraction can disaggregate 50% of the aggregated platelet-rich plasma by ADP and 25% of aggregated PRP by collagen, according to "Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation" by Atanasov AT, Spasov V.(3)

4. Anti diabetes
Metformin, derived from the plant Goal's rue is a medication used in treating type 2 diabetes. In the investigation of the exposure-response properties of metformin were characterized in 12 subjects with type 2 diabetes mellitus suggested that the clinical utility of metformin was maintained over the dose range evaluated with respect to fasting plasma glucose and lactic acid response, according to "Population exposure-response modeling of metformin in patients with type 2 diabetes mellitus" by Hong Y, Rohatagi S, Habtemariam B, Walker JR, Schwartz SL, Mager DE.(4)

5. Anti cancers
In the testing of the new cancer drug with two new guanidine-type alkaloids, nitensidines D and E (1, 2), and the known pterogynine (3), pterogynidine (4), andgalegine(found abundant in Goal's rue) (5), were isolated from the leaves of Pterogyne nitens found that These compounds were tested against a small panel of human cancer cell lines. Compound 2 exhibited cytotoxicity for HL-60 (human myeloblastic leukemia) and SF-245 (human glioblastoma) cells, according to"Cytotoxic guanidine alkaloids from Pterogyne nitens" by Regasini LO, Castro-Gamboa I, Silva DH, Furlan M, Barreiro EJ, Ferreira PM, Pessoa C, Lotufo LV, de Moraes MO, Young MC, Bolzani Vda S."(5)

6. Antihyperglycemic agent
In the synthesis and evaluation of aminoalkylguanidine analogues and derivatives in C57BL/KsJ db/db diabetic mice, found that these compounds are related togalegine, a gamma,gamma-dimethylallylguanidine. Between the newly identified compounds, 1h N-(cyclopropylmethyl)- N'-(4-(aminomethyl)cyclohexylmethyl)guanidine showed the most balanced activity as antihyperglycemic and food intake-reducing agent., according to "Novel substituted aminoalkylguanidines as potential antihyperglycemic and food intake-reducing agents" by Tassoni E, Giannessi F, Brunetti T, Pessotto P, Renzulli M, Travagli M, Rajamäki S, Prati S, Dottori S, Corelli F, Cabri W, Carminati P, Botta M.(6)

7. Etc.


Side effects
1. Overdoses can be danger, please consult with your doctor before taking (a)
2. Do not use the herb in children or if you are pregnant or breast feeding without approval from the related field specialist
3. Do not take Goat's rue if you are on hypoglycemic medication.
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/18055147
(1) http://www.ncbi.nlm.nih.gov/pubmed/11483386
(2) http://www.ncbi.nlm.nih.gov/pubmed/10632090
(3) http://www.ncbi.nlm.nih.gov/pubmed/10462920
(4) http://www.ncbi.nlm.nih.gov/pubmed/18372428
(5) http://www.ncbi.nlm.nih.gov/pubmed/19159272
(6) http://www.ncbi.nlm.nih.gov/pubmed/18465847

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalgia Arthritis (Rheumatica) Treatment: The Individual herb - Green Tea

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                 Polymyalgia Arthritis (Rheumatica)


Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                             Treatments


B.2. Herbal and Traditional Chinese medicine

Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
B.2.1. The Individual Herbs
6. Green Tea
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years.
Epigallocatechin 3-gallate (EGCG), a polyphenol present in green tea, according to the Huazhong University of Science and Technology, Wuhan, exhibited beneficial therapeutic functions including antioxidant, anti-inflammatory and anti-cancer effects, through suppressing MAPK mediated inflammatory responses and oxidative stress(209).
In vascular inflammation, the phytochemical EGCG also regulated the overproduction of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in inhibition of inflammatory rheumatic activity(210).

According to the Texas Tech University Health Sciences Center, epigallocatechin gallate and green tea extract, suppressed the condition caused in part by injury, loss of cartilage structure and function, through their effects in balanced inflammatory and anti-inflammatory pathways(454,211), probably caused by IL-1β, a major cytokine driving the inflammatory processes(455,212)(456,213).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(209) Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress by Chen J1, Xu J1, Li J1, Du L1, Chen T2, Liu P1, Peng S1, Wang M1, Song H3.(PubMed)
(210) Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis by Riegsecker S1, Wiczynski D, Kaplan MJ, Ahmed S.(PubMed)(454,211) Dietary polyphenols and mechanisms of osteoarthritis by Shen CL1, Smith BJ, Lo DF, Chyu MC, Dunn DM, Chen CH, Kwun IS.(PubMed)
(455,212) Green tea: a new option for the prevention or control of osteoarthritis by Katiyar SK, Raman C.(PubMed)
(456,213) Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes by Singh R1, Ahmed S, Malemud CJ, Goldberg VM, Haqqi TM.(PubMed)

Most Common Diseases of Men of 50Plus - Erectile Dysfunction: The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299

With either mental or physical stimulation, your brain signals the nerve ending in the penis to release nitric oxide. Nitric oxide relaxes or dilates blood vessels, enabling them to open up and bring more blood to the penis and helping to create an erection. In this article, we will discuss what causes erectile dysfunction in men.

1. Aging
Starting at the age of 40 the levels of prolactin increases, stimulating the conversion of dihydro-testosterone, causing enlarged prostate and erection difficulty in some men.

2. Uncontrolled diet
Uncontrolled diet that is high in saturated fat and trans fat causing excessive fat build up in the arteries and veins in the penis. Remember that fat is required for function of the brain but excessive intake of fat causes fat to build up in the arteries as well as small veins in the penis and brain. That is also the reason that some experts indicate that erectile dysfunction in men is one of many symptoms of heart diseases and stroke.

3. Smoking
Nicotine is a stimulative, it causes the depletion of oxygen in the bloodstream resulting in the heart to beat faster than usual so that it can carry more oxygen to the cells in our body. It also causes the deduction of the amount of nitric oxide (the substance that relaxes or dilates blood vessels, enabling them to open up and bring more blood to the penis and helping to create and maintain an erection) released from the head of the penis resulting in erectile dysfunction. Cigarette fume contains high amounts of cadmium, the harmful and toxic substance causing calcium to stick on the arterial wall resulting in blocking blood flow to the penile veins creating erectile problems.

4. Excessive alcohol drinking
Excessive alcohol drinking over a long period of time not only damages the liver but also raises the levels of triglycerides in the blood. It also leads to high blood pressure, heart failure and an increased calorie intake causing the arteries and vessels in the penis to be clogged up by harmful cholesterol resulting in erection difficulty.

5. Enlarged ProstateStudies found that there are strong relations between lower urinary tract symptoms and the rate of erectile dysfunction in men with symptoms of enlarged prostate. The main role of the prostate gland is to squeeze fluid into the urethra as sperm moves through during sexual climax. As the prostate enlarges, the layer of tissue surrounding it stops it from expanding, causing the gland to press against the urethra like a clamp on a garden hose resulting in prostate gland muscles surrounding the prostate making it contract and shrink down, increasing the erectile problem.

6. High levels of LDL
The hardening and narrowing of the arteries, causes a reduction in blood flow throughout the body including the vessels in the penis, leading to impotence.

7. Hormone imbalance
Testosterone deficiency can result in a loss of libido and loss of erection. An excess of the hormone prolactin also reduces levels of testosterone. Hormone imbalances can also result from kidney or liver disease.

8. Diabetes
Chronic high levels of blood sugar often damages small blood vessels and nerves throughout the body, impairing the nerve impulses and reducing the blood flow needed for erection.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Erectile Dysfunction 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods LibraryEat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity's Article: Lose Weight with Herbs

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Weight loss is simple: burn more calories than you consume. If you have a healthy diet plan that contains a lot of fruits, vegetables, less meat and dairy foods andare low in saturated and trans fat, it will help you to lose weight and keep it off longer. In this article, beside some other diet plans, we find that some herbs can help you to lose weight and keep it off forever:


1. Fennel seeds
Fennel is known to metabolize and throw off fatty substances through the urinary tract. It has a spicy smell and is rich in vitamin A that helps to improve eyesight. Fennel seeds also aid in digesting and promotes the functioning of the liver, kidneys, and spleen, thereby ensuring the healthy processing and elimination of dietary fat.
2. Cleavers
Cleavers is one of the most well known tonics available to assist the lymphatic system with the healthy clearing of waste and toxins and is an excellent detoxifying agent. Cleavers are not known to lesson the appetite but rather accelerate the fat metabolism.

3. Raspberry leaves
Red Raspberry leaves are very beneficial to the health of many people. Red Raspberry leaves can be used to treat a wide variety of problems. Beside having a reputation as a weight loss aid, raspberry leaf tea is said to help control diarrhea, nausea and help pregnancy, delivery and post delivery easier for the mother.

4. Japanese Green tea
Drinking 3 to 5 cups of green tea at each meal will help to boost your metabolism, which means burning more calories faster.

5. Burdock Roots
Burdock root helps to increase carbohydrate metabolism, and aid the healthy pituitary gland in the regulation of hormones and body weight because of its cleansing and detoxifying abilities.
6 Chickweed
Chickweed was commonly used as a wash for soothing sore eyes, while the leaves were used to ease cuts and sores. It contains high amounts of Vitamin C, protein, flavonoids, phytosterols and glycosides as well. Chickweed may be beneficial to weight loss when included in a healthy lifestyle, proper diet and exercise.


7. Chlorella
Chlorella helps to restore the natural balance of the body and aids any weight loss program by stimulating peristalsis in the intestines.

8. Royal Jelly
Royal jelly is a milky secretion from worker honey bees that's fed to the queen bee to stimulate her growth and development. Royal Jelly has also been said to improve athletic and sexual performance, slowing down the aging process and promoting weight loss.

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Weight Loss Vitamin D

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

                           The Treatments          


In Weight Loss Perspective
Weight loss(733)(734) for obese patients is one of most vital factor to reduce PCOs symptoms(735)(737) and risk of PCOs complications(736)(737). Some researchers found that 5-10% of weight low will improve PCOs features(737) by 25%, including pregnancy(738). How can you lose weight and maintain healthybody for a healthy conception?

                The Weight Loss Vitamin D



Vitamin D is a fat-soluble secosteroids found in small amount in few foods, including salmon, mackerel, sardines and tuna. The vitamin plays an important role in modulation of cellular proliferation, apoptosis induction, tumor growth suppression and promotion in absorption of minerals, including calcium, iron, magnesium, phosphate and zinc.
The serum level of vitamin D
Low levels of micronutrients, including vitamin D are most common among overweight and obese children. According to the study, low serum 25-hydroxyvitamin D3 (25(OH)D) levels not only is associated to insulin resistance and cardiovascular diseases risks(817) but also incidence of obesity(818).
The study of Suspected Nonalcoholic Fatty Liver Disease in Chinese AmericanChildren also supported the link of obesity and metabolic syndrome among Chinese American childrenand suggested that testing for metabolic disorders and low vitamin D levels would be necessary to identify the early indication of NAFLD in childhood will allow for intervention with lifestyle modification, providing a means to reduce the prevalence of NAFLD in children and adults(819).
DR, Peterson CA, and Dr. Belenchia AM. told PubMed "There is a well-established inverse relationship between vitamin D status and obesity; however, it is unknown as to whether vitamin D deficiency contributes to, or is a consequence of obesity"(820). Some researchers suggested that correction of poor vitamin Dstatus through dietary supplementation may be an effective addition to the standard treatment of obesity and its associated insulin resistance(821) as vitamin D deficiency is accounted for the secular trends in the prevalence of obesity and for individual differences in its onset and severity(822).

Vitamin D and adiponectin
A suggestion of association of low levels of Vitamin D and adiponectin is associated to obesity instead of vitamin D itself(823).
Adiponectin is a protein involved in regulating glucose levels as well as fatty acid breakdown.
According to the study by the Università del Piemonte Orientale, in the confirmation Adiponectin tight association with obesity and diabetes mellitus, suggested that multimeric adiponectin may be a key plasma protein that links vitamin D deficiency to pediatric obesity(824).
In support the link between Vitamin D and adiponectin and obesity, the Ramathibodi Hospital, Mahidol University study showed that circulating adiponectin appears to be inversely related to beta cell dysfunction in addition to insulin resistance only in obese women(825). Other in the study insisted that since low serum levels of 1α,25-dihydroxycholecalciferol (DHCC) attenuates (monocyte chemotactic protein-1)MCP-1 and adiponectin production in human adipocytes, thereby reducing the expression of both pro- and anti-inflammatory factors may explain the difficulties so far in determining the role of DHCC in insulin sensitivity and obesity in human(826).

Taking altogether, low serum levels of vitamin D and vitamin D deficiency are associated to increase risk of obesity and obese complications through involvement of vary mechanisms. Over doses of vitamin D supplement may cause excessive calcium absorption, calcification, Urinary stones etc. please make sure to follow the guideline of the Institute of Medicine of the National Academies.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M1.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M1, Kravos NA1, Pfeifer M1, Kocjan T1, Janez A1.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG1, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V1, Vansteelandt S2, T'Sjoen G3, Gerris J4, Somers S4, Vercruysse L4, De Sutter P4.(PubMed)
(817) The association of vitamin D status with cardiometabolic risk factors, obesityand puberty in children by Aypak C1, Türedi O, Yüce A.(PubMed)
(818) Serum 25-hydroxyvitamin D (25-OH-D) in obese adolescents by Garanty-Bogacka B1, Syrenicz M, Goral J, Krupa B, Syrenicz J, Walczak M, Syrenicz A.(PubMed)
(819) Prevalence and Correlates of Suspected Nonalcoholic Fatty Liver Disease in Chinese American Children by Malespin M1, Sleesman B, Lau A, Wong SS, Cotler SJ.(PubMed)
(820) Vitamin D deficiency & childhood obesity: a tale of two epidemics by Peterson CA, Belenchia AM.(PubMed)
(821) Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial by Belenchia AM1, Tosh AK, Hillman LS, Peterson CA.(PubMed)
(822) Vitamin D deficiency is the cause of common obesity by Foss YJ.(PubMed)
(823) Cardiometabolic risk factors related to vitamin d and adiponectin in obese children and adolescents by Kardas F1, Kendirci M, Kurtoglu S.(PubMed)
(824) Pediatric obesity and vitamin D deficiency: a proteomic approach identifies multimeric adiponectin as a key link between these conditions by Walker GE1, Ricotti R2, Roccio M1, Moia S1, Bellone S2, Prodam F2, Bona G2.(PubMed)
(825) Differences in insulin sensitivity, pancreatic beta cell function and circulating adiponectin across glucose tolerance status in Thai obese and non-obese women by Chailurkit LO1, Chanprasertyothin S, Jongjaroenprasert W, Ongphiphadhanakul B.(PubMed)
(826) Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 andadiponectin production in human white adipocytes by Lorente-Cebrián S1, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Aström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M.(PubMed)
(827) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)

The Obesity' Research and Studies - Weight changes in a couples program

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

In the investigation the difference in weight changes of subjects who rated their marriages as more adjusted vs subjects who rated their marriages as less adjusted, conducted by Purdue University, West Lafayette (1),researchers found that Significantly more subjects in the unhappy group also reached ideal weightthan subjects in the happy group (50% vs 7.7%). Subjects' initial MAS scores were significantly and negatively correlated with weight changes at post-treatment and follow-up; partners' MAS scores at the end of treatment were also significantly and negatively correlated to subjects' weight losses at post-treatment. None of the couples was initially maritally distressed but one couple met this criterion (MAS less than or equal to 85) by the end of treatment and follow-up


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) "Weight changes in a couples program: negative association of marital adjustment" by

Black DR.




The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Weight Loss Vitamin C

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

                          The Treatments           


In Weight Loss Perspective
Weight loss(733)(734) for obese patients is one of most vital factor to reduce PCOs symptoms(735)(737) and risk of PCOs complications(736)(737). Some researchers found that 5-10% of weight low will improve PCOs features(737) by 25%, including pregnancy(738). How can you lose weight and maintain healthybody for a healthy conception?


                 The Weight Loss Vitamins C


Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin, found in fresh fruits, berries and green vegetables. It is best known for its free radical scavengers activity and regenerating oxidized vitamin E for immune support.

Vitamin C deficiency and incidence of obesity
Vitamin C and other nutrients deficiency not only are associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808). According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin Cstatus(810)

Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin Cand indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase of Citrus spp. fruits of Spanish origin, grapefruit, containing higher contents of phytochemicals, vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid, in the study of whether the vitamin would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, indicated that addition of vitamin C in diet influences the reduction in body weight gain and food efficiency ratio, and increases in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814).

Taking altogether, deficiency of vitamin C and other nutrients are associated to increase risk of obese incidence. Vitamin C may be effective in induced weight loss for obese subjects due to its positive interaction in inhibiting oxidative stress causes of endothelial dysfunction. Daily ingestion of high-dose vitamin C may be considered safe, but in rare incidence, overdoses in a prolonged period of time, may cause intra-renal oxalate crystal deposition, a fatal nephrotoxicity(815)(816).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
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(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
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(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
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(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M1.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M1, Kravos NA1, Pfeifer M1, Kocjan T1, Janez A1.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG1, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V1, Vansteelandt S2, T'Sjoen G3, Gerris J4, Somers S4, Vercruysse L4, De Sutter P4.(PubMed)
(807) High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice by Tranberg B1, Hansen AK, Lykkesfeldt J.(PubMed)
(808) Zinc, iron and vitamins A, C and e are associated with obesity, inflammation, lipid profile and insulin resistance in mexican school-aged children by García OP1, Ronquillo D, del Carmen Caamaño M, Martínez G, Camacho M, López V, Rosado JL.(PubMed)
(809) Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: results from a cross-sectional study by García OP1, Ronquillo D, Caamaño Mdel C, Camacho M, Long KZ, Rosado JL.(PubMed)
(810) Strategies for healthy weight loss: from vitamin C to the glycemic response by Johnston CS.(PubMed)
(811) Mechanisms of endothelial dysfunction in obesity(Science direct)
(812) Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C. by Perticone F1, Ceravolo R, Candigliota M, Ventura G, Iacopino S, Sinopoli F, Mattioli PL.(PubMed)
(813) Phytochemistry and biological activity of Spanish Citrus fruits by Gironés-Vilaplana A1, Moreno DA, García-Viguera C.(PubMed)
(814) Anti-obesity effects of chitosan and psyllium husk with L-ascorbic acid in guinea pigs by Jun SC1, Jung EY, Hong YH, Park Y, Kang Dh, Chang UJ, Suh HJ.(PubMed)
(815) Fatal vitamin C-associated acute renal failure by McHugh GJ, Graber ML, Freebairn RC.(PubMed)
(816) Ascorbic acid overdosing: a risk factor for calcium oxalate nephrolithiasis by Urivetzky M, Kessaris D, Smith AD.(PubMed)