The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Stress Response and Management herbal Ashwagandha

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).


 The prevention and management In Herbal Medicine

Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).


                 The stress management herbs

Stress in a natural reaction of human fight or fight response induced by pressure due to environmental condition or a stimulus. Long term stress can cause deleterious and cumulative effects on human body(1104), including emotional or cognitive problems, such as an increased risk of attentional deficit/hyperactivity, anxiety, and language delay(1103), especially for people with chronic illness, including women with Polycystic Ovarian Syndrome (PCOs)(1105).


                             Ashwagandha (Withania somnifera)


Ashwagandha(Withania somnifera), also known as Indian Ginseng is a nightshade plant belongings to the family Solanaceae, native to India, northern Africa, and the Middle East, used in Ayurvedic medicine over 3000 years(1101) as antitumors(1107)(1108), anti ulcers(1111), anti-stress(1112)(1115)(1118), improved cognition dysfunction(1109)(1110)(1118), anti-inflammatory(1113)(1116), antioxidant(1114)(1117), promoted immunity(1120)(1121), anti-aging(1119), etc., herbal medicine.

Phytochemicals(1102)
1. Isopelletierine
2. Anaferine
3. Cuseohygrine
4. Anahygrine
5. Withanolides
6. Withaferins
7. Saponins
8. Sitoindosides
9. Acylsterylglucosides
10. Z-Guggulsterone(1106)

10. Etc.

Epidemiologically strong evidences suggested that herbal ashwagandha processes anti stress related disorders( induced by oxidative stress(1122)(1123) and long term stress(1123) effects, probably through its antioxidant(1123)(1124)(1126)(1114)(1117), anti-stress(1112)(1115)(1118), anti-inflammatory(1113)(1116), immunomoduratory(1120)(1121) effects. In rat model, hydroalcoholic extract exerted its antioxidant effect against psychological symptoms(1132) induced by long term stress, such as reduced motor performance(1124), cognitive impairment(1125)(1126, anxiety(1127)(1128), sleep disorder(1129)(1130), depression(1131), etc. In stress induced by phyisological symptoms, the herb has showen to reduce fatigue(1133) risk of hypertension(1134), risk of stroke(1135). risk of diabetes(1136), improve energy(1132), etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed) (1106) Simultaneous Estimation of Withaferin A and Z-Guggulsterone in Marketed Formulation by RP-HPLC by Agrawal P1, Vegda R2, Laddha K2.(PubMed)
(1101) Steroidal lactones from Withania somnifera, an ancient plant for novel medicine by Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J.(PubMed)
(1102) An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda by Narendra Singh, Mohit Bhalla, Prashanti de Jager, and Marilena Gilca(PubMed)
(1103) Antenatal maternal stress and long-term effects on child neurodevelopment: how and why? by Talge NM1, Neal C, Glover V; Early Stress, Translational Research and Prevention Science Network: Fetal and Neonatal Experience on Child and Adolescent Mental Health.(PubMed)
(1104) Immediate and long-term effects of meditation on acute stress reactivity, cognitive functions, and intelligence by Singh Y1, Sharma R, Talwar A.(PubMed)
(1105) The potential implications of a PCOS diagnosis on a woman's long-termhealth using data linkage by Hart R1, Doherty DA.(PubMed)
(1106) Simultaneous Estimation of Withaferin A and Z-Guggulsterone in Marketed Formulation by RP-HPLC by Agrawal P1, Vegda R2, Laddha K2.(PubMed)

(1107) Selective killing of cancer cells by leaf extract of Ashwagandha: components, activity and pathway analyses by Widodo N1, Takagi Y, Shrestha BG, Ishii T, Kaul SC, Wadhwa R.(PubMed)
(1108) Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect by Widodo N1, Kaur K, Shrestha BG, Takagi Y, Ishii T, Wadhwa R, Kaul SC.(PubMed)
(1109) Effect of standardized aqueous extract of Withania somnifera on tests ofcognitive and psychomotor performance in healthy human participants by Pingali U1, Pilli R1, Fatima N1.(PubMed)
(1110) Randomized placebo-controlled adjunctive study of an extract of withaniasomnifera for cognitive dysfunction in bipolar disorder by Chengappa KN1, Bowie CR, Schlicht PJ, Fleet D, Brar JS, Jindal R.(PubMed)
(1111) Evaluation of the anti-ulcer activity of NR-ANX-C (a polyherbal formulation) in aspirin & pyloric ligature induced gastric ulcers in albino rats by Nair V1, Arjuman A, Gopalakrishna HN, Dorababu P, Mirshad PV, Bhargavan D, Chatterji D.(PubMed)
(1112) Effect of Withania somnifera (Ashwagandha) root extract on amelioration of oxidative stress and autoantibodies production in collagen-induced arthritic rats by Khan MA, Subramaneyaan M, Arora VK, Banerjee BD, Ahmed RS.(PubMed)
(1113) Evaluation of anti-inflammatory effect of Withania somnifera root on collagen-induced arthritis in rats by Gupta A1, Singh S.(PubMed)
(1114) Protective effect of Withania somnifera root powder in relation to lipid peroxidation, antioxidant status, glycoproteins and bone collagen on adjuvant-induced arthritis in rats by Rasool M1, Varalakshmi P.(PubMed)
(1115) Withania somnifera Improves Semen Quality in Stress-Related Male Fertility by Mahdi AA1, Shukla KK, Ahmad MK, Rajender S, Shankhwar SN, Singh V, Dalela D.(PubMed)
(1116) Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation by SoRelle JA1, Itoh T, Peng H, Kanak MA, Sugimoto K, Matsumoto S, Levy MF, Lawrence MC, Naziruddin B.(PubMed)
(1117) Evaluation of antioxidant potential of Rasayana drugs in healthy human volunteers by Kuchewar VV1, Borkar MA2, Nisargandha MA3.(PubMed)
(1118) Withania somnifera (Ashwagandha) in neurobehavioural disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis by Durg S1, Dhadde SB, Vandal R, Shivakumar BS, Charan CS.(PubMed)
(1119) In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and β-amyloid(1-42)-induced cytotoxicity in differentiated PC12 cells by Kumar S1, Seal CJ, Howes MJ, Kite GC, Okello EJ.(PubMed)
(1120) Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice by Kushwaha S1, Roy S, Maity R, Mallick A, Soni VK, Singh PK, Chaurasiya ND, Sangwan RS, Misra-Bhattacharya S, Mandal C.(PubMed)
(1121) Molecular insight into the immune up-regulatory properties of the leaf extract of Ashwagandha and identification of Th1 immunostimulatory chemical entity by Khan S1, Malik F, Suri KA, Singh J.(PubMed)
(1122) Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha by Kaur K1, Rani G, Widodo N, Nagpal A, Taira K, Kaul SC, Wadhwa R.(PubMed)
(1123) Anti-oxidant effect of Withania somnifera glycowithanolides in chronic footshock stress-induced perturbations of oxidative free radical scavenging enzymes and lipid peroxidation in rat frontal cortex and striatum by Bhattacharya A1, Ghosal S, Bhattacharya SK.(PubMed)
(1124) Evaluation of Withania somnifera in a middle cerebral artery occlusion model of stroke in rats by Chaudhary G1, Sharma U, Jagannathan NR, Gupta YK.(PubMed)
(1125) Propoxur-induced acetylcholine esterase inhibition and impairment of cognitive function: attenuation by Withania somnifera by Yadav CS1, Kumar V, Suke SG, Ahmed RS, Mediratta PK, Banerjee BD.(PubMed)
(1126) Attenuation of oxidative damage-associated cognitive decline by Withaniasomnifera in rat model of streptozotocin-induced cognitive impairment by Ahmed ME1, Javed H, Khan MM, Vaibhav K, Ahmad A, Khan A, Tabassum R, Islam F, Safhi MM, Islam F.(PubMed)
(1127) An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera) by Pratte MA1, Nanavati KB, Young V, Morley CP.(PubMed)
(1128) Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence by Sarris J1, McIntyre E, Camfield DA.(PubMed)
(1129) Effect of Withania somnifera on Sleep-Wake Cycle in Sleep-Disturbed Rats: Possible GABAergic Mechanism by Kumar A1, Kalonia H.(PubMed)
(1130) Protective effect of Withania somnifera Dunal on the behavioral and biochemical alterations in sleep-disturbed mice (Grid over water suspended method) by Kumar A1, Kalonia H.(PubMed)
(1131) Protective effect of Withania somnifera dunal root extract against protracted social isolation induced behavior in rats by Gupta GL1, Rana AC.(PubMed)
(1132) An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda by Singh N1, Bhalla M, de Jager P, Gilca M.(PubMed)
(1133) Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients by Biswal BM1, Sulaiman SA, Ismail HC, Zakaria H, Musa KI.(PubMed)
(1134) Withania somnifera shows a protective effect in monocrotaline-induced pulmonary hypertension by Kaur G1, Singh N, Samuel SS, Bora HK, Sharma S, Pachauri SD, Dwivedi AK, Siddiqui HH, Hanif K.(PubMed)
(1135) Withania somnifera Improves Ischemic Stroke Outcomes by Attenuating PARP1-AIF-Mediated Caspase-Independent Apoptosis by Raghavan A1, Shah ZA.(PubMed)
(1136) The aqueous extract of Withania coagulans fruit partially reverses nicotinamide/streptozotocin-induced diabetes mellitus in rats by Shukla K1, Dikshit P, Shukla R, Gambhir JK.(PubMed)

Most Common Diseases of Men of 50Plus - Prostate Health - The Effects of Chinese Herbs

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Starting at age 40, the levels of by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Besides aging there are many other causes of enlarged prostate and some of them might result in prostate cancer. In this article, we will discuss how to use herbs to prevent and treat enlarged prostate as well as prostate cancer. Chinese herbalists believe that prostate gland enlargement results from an accumulation of dampness and heat in the Urinary Bladder, deficiency of Kidney Qi and blood stagnation. Therefore eliminating the stagnation, activating the blood circulation, regulating the Qi and clearing the damp-heat will help to cure enlarged prostate and some of them might become prostate cancer if left untreated.

1. Saw palmetto
Saw palmetto has been used for over a century in traditional Chinese medicine in treating pain in the lower back, inflammation and enlargement by inhibiting dihydrotestosterone, thereby reducing its stimulation for cancerous cell multiplication.

2. Patrinia (Bai jiang cao)
Patrinia helps the body get rid of prostate inflammation and damp heat that exists in the body. In Chinese medicine damp heat in the prostate could be caused by bacteria infection, drugs and other conditions such as a habit of eating hot, spicy or greasy foods.

3. Lu lu tong (liquid amber)
Lu lu tong has the ability to improve qi and blood circulation . It also helps to reduce the abdominal, back and knee pain caused by damp heat as well as difficult urination because of bladder or prostate inflammation.

4. He shou wu
He shou wu contains several derivatives of tetrahydroxystilbene. These antioxidants and anti-inflammatory compounds may act as an estrogen, reducing levels of circulating male hormones such as DHT that fuel the growth of prostate cancer.

5. Niu xi (Achyranthes)
Niu xi contains triterpenoid saponins and sitosterol that possesses anti-inflammatory effects in both enlarged prostate and prostate cancer inflammation. It also helps to nourish the kidney liver and reduce symptoms of damp heat and difficult urination as well as stiffness and pain of lower back.
6. Gui Zhi (tokoro)Gui Zhi is used for urinary tract disorder that pertains to ying qi levels which is the main cause of prostate inflammation. It also is used as a tonic and blood purifier.

7. Astragalus root
Astragalus root is a sprawling perennial legume. The Chinese medicine uses the dried sliced or powdered root of the plant to enhance immune function by increasing the activity of certain white blood cells, which increases the production of antibodies. It also helps to increase the body's resistance to infections, to heal the allergies, and to raise and renew the vitality.

8. Che Qian zi (plantago seed)
It is mainly used for stone strangury caused by lower burner damp-heat, such as the symptoms of aching pain in the lumbus and abdomen, poor urination or with hematuria, and urinary tract stones.

9. Vaccaria seed
It is used to reduce pain and stiffness in the lower back, drain excessive damp heat, invigorate blood and treat difficult urination.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Erectile Dysfunction
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity's Weight Loss Recipes: Onion salad

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The best Weight Loss and Immune Protection Recipe attributed to Company's Coming Salads by Jean Parè

One of the best creamy good extras to serve
Granulated sugar 1/2 cup (125ml)
Water 1/3 cup (75 ml)
Vinegar 1/3 cup (75ml)
Salt 11/2 tsp. (7 ml)
Spanish onion, sliced and cut up 4
salad dressing (mayonnaise) 1 cup (250ml)
celery seed 1tsp. (5ml)
Combined sugar, vinegar and salt in bowl. Stir sugar until dissolves. Add onion to vinegar mixture. let stand for 3 hours or overnight.
Combine salad dressing with celery seed. Drain onion well. Stir into salad dressing mixture. Serve 8 to 10.
variation. Use older vinegar instead of white.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Eat, Play, Love: Adolescent and Parent Perceptions of the Components of a Multidisciplinary Weight Management Program

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Eat, Play, Love: Adolescent and Parent Perceptions of the Components of a Multidisciplinary Weight Management Program

In the interviews performed (spring 2010) with past participants of the Michigan Pediatric Outpatient Weight Evaluation and Reduction program. Transcripts were reviewed and themes identified, found that parents (38) and adolescents (25) were interviewed separately; similar themes emerged. Theme 1: Support/encouragement-Participants emphasized the importance of a supportive environment with a positive, compassionate approach from providers. Theme 2: Exercise-Fun, achievable activities were a valued means of making exercise enjoyable and building self-efficacy. Theme 3: Nutrition-Hands on demonstrations and tangible suggestions were preferred over activities such as self-monitoring. Theme 4: Behavioral factors-Participants valued the opportunity to hear their peers' experiences. However, individual/family sessions addressing their personal concerns were also viewed as important. Conclusion. Beyond program content, participants valued a supportive environment emphasizing health over habitus(1)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) " Eat, Play, Love: Adolescent and Parent Perceptions of the Components of a Multidisciplinary Weight Management Program" by Woolford SJ, Sallinen BJ,Schaffer S, Clark SJ.

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Food therapy - Vegetables - GINGER-ROOTS (Zingiber officinale)(1)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

GINGER-ROOTS (Zingiber officinale)







The second superfood has been used for thousand of years by mankind, we will try to give you as much information as possible. Here are some ways that ginger has been used medicinally.

**GINGER for treating Migraine: Mix some powdered gingers into a glass of hot water and drink. Daily approach worked for long time migraine sufferer.

** GINGER for NAUSEA: For centuries, sailors have relied on ginger to keep them free of seasickness and prevent nausea when you go on board. Eat some Ginger 1/2 hour before boarding.

**GINGER for OSTEOARTHRITIS:Ginger has a thytochemical called curcumin that helps reduce inflammation. It helps to protect your joints.Before we go further, we would like to remind you of cautions of using Superfood GINGER. While GINGER can help to strengthen anticoagulants such as heparin, warfarin and ticlopidine by helping your blood get less sticky but ginger raises the odd of bleeding.

**GINGER for EYE disorders: Taking Ginger will increase blood circulation so that more nutrition can reach your eye.

**GINGER for HEART DISEASE: Ginger helps to lower cholesterol levels, elevated blood pressure and prevent blood clots in the arterial walls when taken with vitamin E. It also helps to stimulate and revitalize the heart muscle and strengthen the peripheral's circulation.

**GINGER for HYPOGLYCEMIA: Ginger helps to Balance Blood Sugar. Please note that hypoglycemia people generally need to eat frequently, small meals to provide the body with steady supply of food that easily and slowly converts to glucose.

**GINGER for Motion Sickness: The key to ginger's effectiveness appears to stem from the oils it contain. Gingerols and shogaols. These oils calm the intestinal tract and slowly depresses the central nervous system.

** GINGER for ARTHIRITIS: Traditionally used as an Ayurvedic herb, it is capable of relieving pain caused by arthiritis joints.

** GINGER for Cancer: Ginger will alleviate nausea associated with chemotherapy. It can be taken as tea.Above are only some of Ginger's uses to treat diseases. There are many more effectivenesses of ginger, such as carpal tunnel syndrome, Cerebral Palsy, Cholesterol, Cold, Depression, digestive disorders,..........

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Phytochemicals in Foods - The Effects of Gallic acid

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                       Gallic acid


Gallic acid is a phytochemical in the class of Phenolic acids, found abundantly in tea, mango, strawberries, rhubarb, soy, etc.

Health Benefits
1. Cytotoxic and antioxidative activities
In the investigation of the bioactivity guided isolation and characterization of phytoconstituents, indicated the extract showed strong radical scavenging effects against DPPH, nitric oxide (NO) and superoxide (SO) radicals comparable to that of known antioxidants 3-t-butyl-4-hydroxyanisole, ascorbic acid (vitamin C), and quercetin in addition to its cytotoxic activities against HEP-2 (human larynx epidermoid carcinoma) and RD (human rhabdomyosarcoma) cell lines based on MTT assay for growth inhibition. The gallic acid equivalent total phenolic content of the plant was found to be 79.94mg/g dry extract. Phenylethanoid glycosides, verbascoside and calceorioside A were isolated from the most active fraction and both compounds showed strong radical scavenging activity against tested radicals and cytotoxicity against HEP-2, RD and MCF-7 (human breast adenocarcinoma) cell line, according to "Cytotoxic and antioxidative activities of Plantago lagopus L. and characterization of its bioactive compounds" by Sebnem Harput U, Genc Y, Saracoglu I.(1)

2. Breast cancer
In the analyzing the Sanguisorba officinalis L. (SA) effects on human breastcancer utilizing in vitro and in vivo methodologies, found that SA inhibited proliferation, induced S phase arrest and triggered mitochondrial pathway apoptosis in both cancer cells. Angiogenesis experiments revealed that SA inhibited VEGF expression in both cancer cell lines. Meanwhile, the proliferation, tube formation and migration abilities of endothelial cells were also inhibited. In vivo experiments demonstrated that SA reduced tumor size and neoangiogenesis in both cancer xenografts. Gallic acid and ellagic acid were finally identified as bioactive compounds in SA, according to "Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis" by Wang Z, Loo WT, Wang N, Chow LW, Wang D, Han F, Zheng X, Chen JP.(2)

3. Anti-leukemic effects
In the investigation of the apoptotic activity induced by GA on chronic myeloid leukemia (CML) cell line-K562 and the underlying mechanism, found that GA inhibited BCR/ABL tyrosine kinase and NF-κB. In conclusion, GA induced apoptosis in K562 cells involves death receptor and mitochondrial-mediated pathways by inhibiting BCR/ABL kinase, NF-κB activity and COX-2, according to "Anti-leukemic effects of gallic acid on human leukemia K562 cells: Downregulation of COX-2, inhibition of BCR/ABL kinase and NF-κB inactivation" by

Chandramohan Reddy T, Bharat Reddy D, Aparna A, Arunasree KM, Gupta G, Achari C, Reddy GV, Lakshmipathi V, Subramanyam A, Reddanna P.(3)

4. Antioxidants
In the evaluation of the antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from Cystoseira sedoides (Desfontaines) C. Agardh, indicated that the F-CHCl(3) and F-AcOEt fractions showed significant total phenolic content at 55.09 and 61.30 mg gallic-acid equivalent/g dried sample, respectively. Using the DPPH method, the F-CHCl(3) and the F-AcOEt fractions exhibited the strongest radical scavenging activity, with IC(50) 120 µg/mL for F-CHCl(3) and 121 µg/mL for F-AcOEt, which approaches the activity of the powerful antioxidant standard, Trolox (IC(50) = 90 µg/mL), according to "Antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from the Mediterranean brown seaweed Cystoseira sedoides" by Mhadhebi L, Laroche-Clary A, Robert J, Bouraoui A.(4)

5. Anti cancers
In the identification of gallic acid (GA) as a major bioactive cytotoxic constituent of a polyherbal Ayurvedic formulation - triphala (TPL) on (AR)(+) LNCaP prostatecancer and normal epithelial cells, found that TPL contains 40% unidentified polyphenolic acids, of which 2.4% comprised GA. GA induced severe morphological alterations and was about 3-fold more cytotoxic towards cancercells than TPL. This activity increased further in the presence of dihydrotestosterone. GA toxicity on normal cells was low at 72 h. Combination of GA with flutamide caused higher toxicity to cancer cells than either of the compounds alone, according to "Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells" by Russell LH Jr, Mazzio E, Badisa RB, Zhu ZP, Agharahimi M, Millington DJ, Goodman CB.(5)

6. Leukemia
In the investigation of the apoptotic effects induced by GA in human promyelocytic leukemia HL-60 cells, and clarify the underlying mechanism, found that GA-mediated apoptosis of HL-60 cells mainly depended on up-regulation of the mRNA of caspase-8, caspase-9, caspase-3, AIF and Endo G. In conclusion, GA-induced apoptosis occurs through the death receptor and mitochondria-mediated pathways, according to "Gallic acid induces G₀/G₁ phase arrest and apoptosis in human leukemia HL-60 cells through inhibiting cyclin D and E, and activating mitochondria-dependent pathway" by Yeh RD, Chen JC, Lai TY, Yang JS, Yu CS, Chiang JH, Lu CC, Yang ST, Yu CC, Chang SJ, Lin HY, Chung JG(6)

7. Colon cancer
found that In vivo, GT (25 mg/kg body weight) injected intraperitoneally (i.p.) prior to or after tumor inoculation significantly decreased the volume of human coloncancer xenografts in NOD/SCID mice. GT-treated xenografts showed significantly lower microvessel density (CD31) as well as lower mRNA expression levels of IL-6, TNF-α and IL-1α and of the proliferation (Ki-67) and angiogenesis (VEGFA) proteins, which may explain GTs in vivo anti-tumorigenic effects, according to "Gallotannin inhibits NFĸB signaling and growth of human colon cancerxenografts" by Al-Halabi R, Bou Chedid M, Abou Merhi R, El-Hajj H, Zahr H, Schneider-Stock R, Bazarbachi A, Gali-Muhtasib H.(7)

8. Anti-neoplastic effects
In the investigation of the effects of TS on various human oral squamous carcinoma cell lines (HOSCC), including UM1, UM2, SCC-4, and SCC-9, found that FACScan analysis revealed that the leaf extract induced apoptosis or a combination of apoptosis and necrosis, depending on cell type. Microarray and semi-quantitative RT-PCR analysis for apoptotic-related gene expression revealed that 3,4,5-trihydroxybenzoic acid (gallic acid, one of the major bioactive compounds purified from TS extract) up-regulated pro-apoptotic genes such TNF-α, TP53BP2, and GADD45A, and down-regulated the anti-apoptotic genes Survivin and cIAP1, resulting in cell death. This study suggests that gallic acid, the major bioactive compound present, is responsible for the anti-neoplastic effect of Toona sinensis leaf extract, according to "Anti-neoplastic effects of gallic acid, a major component of Toona sinensis leaf extract, on oral squamous carcinoma cells" by Chia YC, Rajbanshi R, Calhoun C, Chiu RH.(8)

9. Anti cancers, anti inflammatory and anti diabetic effects
In the review of 1, 2, 3, 4, 6-penta-O-galloyl-beta-D-glucose (PGG) is a polyphenolic compound highly enriched in a number of medicinal herbals, indicated that Chemically and functionally, PGG appears to be distinct from its constituentgallic acid or tea polyphenols. For anti-cancer activity, three published in vivo preclinical cancer model studies with PGG support promising efficacy to selectively inhibit malignancy without host toxicity. Potential mechanisms include anti-angiogenesis; anti-proliferative actions through inhibition of DNA replicative synthesis, S-phase arrest, and G(1) arrest; induction of apoptosis; anti-inflammation; and anti-oxidation. Putative molecular targets include p53, Stat3, Cox-2, VEGFR1, AP-1, SP-1, Nrf-2, and MMP-9. For anti-diabetic activity, PGG and analogues appear to improve glucose uptake, according to "Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose" by Zhang J, Li L, Kim SH, Hagerman AE, Lü J(9)

10. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22289578
(2) http://www.ncbi.nlm.nih.gov/pubmed/22316502
(3) http://www.ncbi.nlm.nih.gov/pubmed/22245431
(4) http://www.ncbi.nlm.nih.gov/pubmed/22115493
(5) http://www.ncbi.nlm.nih.gov/pubmed/22110195
(6) http://www.ncbi.nlm.nih.gov/pubmed/21868525
(7) http://www.ncbi.nlm.nih.gov/pubmed/21532339
(8) http://www.ncbi.nlm.nih.gov/pubmed/21081858
(9) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822717/