Wednesday, June 22, 2016

Food therapy - Vegetables - Kale (Brassica Oleracea)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                      Kale

Kale is a species of Brassica Oleracea, belong to the family Brassicaceae, native to coastal southern and western Europe. Since kale's leave is highly nutritious and easy to growth with range of long season from the middle of winter through the beginning of spring, it is cultivated as foods in most part of Europe.

Nutrients
1. Carbohydrate
2. Dietary Fiber
3. Vitamin A
4. Vitamin C
5. Niacin
6. Vitamin B1 (thiamine)
7. Vitamin B2 (riboflavin)
8. Vitamin B6
9. Folate
10. Pantothenic Acid
11. Vitamin K
12. Vitamin E
13. Copper
14. Potassium - 296 mg
15. Phosphorus
16. Magnesium
17. Calcium
18. Iron
19. Sodium
20. Zinc
21. Copper
22. Manganese
23. Selenium
24. Omega 3 Fatty Acid
25. Tryptophan
26. Etc.

Health Benefits
A. Health benefits according to studies
1. Vitamin K1 (Phylloquinone)
Vitamin K1 is commonly used to treat warfarin toxicity, and an antidote for coumatetralyl. In the research of the absorption and plasma disappearance of vitamin K were investigated by uniformly labelling phylloquinone in kale with carbon-13 found that Modelling results demonstrated a mean (n 6) bioavailability of phylloquinone from kale to be 4.7%. Plasma and tissue half-times for phylloquinone were found to be 8.8 and 215 h, respectively, according to "Vitamin K absorption and kinetics in human subjects after consumption of 13C-labelled phylloquinone from kale" by Novotny JA, Kurilich AC, Britz SJ, Baer DJ, Clevidence BA.(a)

2. Beta-carotene, lutein, and retinol
In the investigation of plasma appearance of labeled beta-carotene, lutein, and retinol in humans after consumption of kale found that A positive relationship was observed between baseline plasma retinol levels and [13C]retinol plasma response. It is possible that this relationship was mediated either through some aspect of beta-carotene absorption or via the common pathways of metabolism for postdose and endogenous retinoid, according to "Plasma appearance of labeled beta-carotene, lutein, and retinol in humans after consumption of isotopically labeled kale" by Novotny JA, Kurilich AC, Britz SJ, Clevidence BA.(b)

3. Hepatic lutein concentrations
In the evaluation of the chemopreventive potential of water extracts of the Brassicavegetables cabbage and kale found that despite the absence of inhibitory effects of cabbage and kale aqueous extracts on placental glutathione S-transferase-positive preneoplastic lesions (PNL)., these Brassica vegetables presented protection against DNA damage, an effect possibly related to increased hepatic lutein concentrations. However, it must be pointed out that the cause-effect relationship between lutein levels and protection is hypothetical and remains to be demonstrated, according to "Water extracts of cabbage and kale inhibit ex vivo H(2)O(2)-induced DNA damage but not rat hepatocarcinogenesis" by Horst MA, Ong TP, Jordão AA Jr, Vannucchi H, Moreno FS, Lajolo FM.(c)

4. Ulcerative colitis
In the examination of PEO, an essential oil containing >95% natural PEITC, a phenethylisothiocyanate (PEITC) produced by Brassica food plants found that PEO might be a promising candidate to develop as a treatment for ulcerative colitis patients. The disease attenuation by PEO is likely associated with suppression of activation of STAT1 transcription and inhibition of pro-inflammatory cytokines, according to "Dietary phenethylisothiocyanate attenuates bowel inflammationin mice' by Dey M, Kuhn P, Ribnicky D, Premkumar V, Reuhl K, Raskin I.(d)

5. Arthritis and associated disorders
In the observation of 3,3'-Diindolylmethane (DIM), a natural compound formed during the autolysis of glucobrassicin present in Brassica food plants found that in vitro and in vivo studies confirmed the inhibition of RANKL by DIM. DIM has shown anti-arthritis activity in animal models via inhibiting the expression of RANKL, and thus may offer potential treatments for arthritis and associated disorders, according to "3,3'-Diindolylmethane attenuates experimental arthritis and osteoclastogenesis" by Dong L, Xia S, Gao F, Zhang D, Chen J, Zhang J.(e)

6. Etc

B. Health benefits according to concentration
1. Vitamin K
Vitamin K not only plays an important role in protecting our skin from aging, it is also needed for the proper clotting of blood, thus decreasing the risk of excessive bleeding, in a study of "Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!" by Kasatkar P, Shetty S, Ghosh K., posted inPubMed, researchers found that Laboratory tests confirmed acquired bleeding diathesis due to vitamin K deficiency, which was corrected after adequate vitamin K supplementation. VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis.

2. Vitamin A
Vitamin A is not only important in preventing types I diabetes, according to "A close relationship between type 1 diabetes and vitamin A-deficiency and matrix metalloproteinase and hyaluronidase activities in skin tissues" byTakahashi N, Takasu S.(I) but also may be associated with compromised bone health, according to "Vitamins and bone health: beyond calcium and vitamin D" by Ahmadieh H, Arabi A.(II)

3. Vitamin C
a. Asthma
Vitamin C is one of the key antioxidant vitamins which is abundant in the extracellular fluid lining the lung and low vitamin C intake has been associated with pulmonary dysfunction, such as asthma, according to the study of "Vitamin Csupplementation for asthma" by Kaur B, Rowe BH, Arnold E.(III)

b. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.(IV)

4. Manganese
Manganese beside plays an vital role for the proper and normal growth of human bone structure (accodring to the study of "Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants" by Pabbruwe MB,Standard OC, Sorrell CC, Howlett CR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/15109850)), it also helps to reduce the risk of cancer, (according to the study of "The effects of 3, 4 or 5 amino salicylic acids onmanganese-induced neuronal death: ER stress and mitochondrial complexes" by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

5. Dietary fiber
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(V)

6. Etc

C. Other health benefits
1. Free radicals
Since kale is a highly nutritious vegetable with powerful antioxidant properties, it enhances the immune system in guarding our body
a) Against the forming of free radical, cell damage caused by oxidation, irregular cell growth causes of tumors and cancer, according to the study of "Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: a meta-analysis of randomized controlled trials" by Jiang L, Yang KH, Tian JH, Guan QL, Yao N, Cao N, Mi DH, Wu J, Ma B, Yang SH., posted in PubMed(1)
b) Against the risk of inflammation and infection caused by foreign invasion, according to "IX. Immune System" posted in Antioxidants(2)

2. Bone density
Magnesium enhances the digestive system in absorbing calcium, by maintaining the proper ratio between them, according to the study of "Associations of calcium and magnesium in serum and hair with bone mineral density in premenopausal women" by Song CH, Barrett-Connor E, Chung JH, Kim SH, Kim KS., posted in PubMed(3)

3. Skin health
Vitamin C and K in kale decrease the risk of bleeding (Vitamin C and K) and protects the loss skin under layer (vitamin K) due to aging. Vitamin A maintains normal skin health by switching on genes and differentiating (immature skin cells) into mature epidermal cells and vitamin E and C protest skin from aging, according to the study of "Main approaches for delivering antioxidant vitamins through the skin to prevent skin ageing" by Gašperlin M, Gosenca M., posted in PubMed(4)

4. Vision health

Vitamin A protects against mascular degeneration caused by free radical, promotes good vision, according to the study of "The intake of carotenoids in an older Australian population: The Blue Mountains Eye Study" by Manzi F, Flood V, Webb K, Mitchell P., posted in PubMed(5)


5. Etc.

Side Effects
It is advised for people with untreated kidney and gallbladder should consult with their doctor before consuming kale due to measurable amount of oxalates.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20420753
(b) http://www.ncbi.nlm.nih.gov/pubmed/15897604
(c) http://www.ncbi.nlm.nih.gov/pubmed/20401431
(d) http://www.ncbi.nlm.nih.gov/pubmed/20423518
(e) http://www.ncbi.nlm.nih.gov/pubmed/19854159

(I) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(II) http://www.ncbi.nlm.nih.gov/pubmed/21967159
(III) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(IV) http://www.ncbi.nlm.nih.gov/pubmed/21986888
(V) http://www.ncbi.nlm.nih.gov/pubmed/20713332

(1) http://www.ncbi.nlm.nih.gov/pubmed/20661819
(2) http://the-anti-aging-guide.blogspot.com/2011/04/ix-immune-system.html
(3) http://www.ncbi.nlm.nih.gov/pubmed/17848724
(4) http://www.ncbi.nlm.nih.gov/pubmed/21599565
(5) http://www.ncbi.nlm.nih.gov/pubmed/12020387

Obesity and Obesity's complication - The association of Obesity on Dementia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)


Dementia is defined as a condition of deteriorate gradually of cognitive ability ofmemory, thinking, language, judgment, and behavior.

The association of Obesity on Dementia
1. In a study of "Midlife and late-life obesity and the risk of dementia: cardiovascular health study" by Fitzpatrick AL, Kuller LH, Lopez OL, Diehr P, O'Meara ES, Longstreth WT Jr, Luchsinger JA.,posted in PubMed, researchers found that these results help explain the "obesity paradox" as differences indementia risk across time are consistent with physical changes in the trajectory toward disability.

2. According to the abstract of study of "Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease" by Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kåreholt I, Winblad B, Helkala EL, Tuomilehto J, Soininen H, Nissinen A., posted in PubMed, researchers found that Obesity at midlife is associated with an increased risk of dementia and AD later in life. Clustering of vascular risk factors increases the risk in an additive manner. The role of weight reduction for the prevention of dementia needs to be further investigated.

3. In a study of "Central obesity and increased risk of dementia more than three decades later" by Whitmer RA, Gustafson DR, Barrett-Connor E, Haan MN, Gunderson EP, Yaffe K., posted in PubMed, researchers found that Centralobesity in midlife increases risk of dementia independent of diabetes and cardiovascular comorbidities. Fifty percent of adults have central obesity; therefore, mechanisms linking central obesity to dementia need to be unveiled.

4. According to the study of "Obesity in middle age and future risk ofdementia: a 27 year longitudinal population based study" by Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP Jr, Yaffe K., posted in PubMed, researchers found that Obesity in middle age increases the risk of future dementiaindependently of comorbid conditions.

5. In a study of "Measures of adiposity and dementia risk in elderly persons" by Luchsinger JA, Patel B, Tang MX, Schupf N, Mayeux R.posted in PubMed, researchers found that Compared with persons in the first quartile of BMI, persons in the third quartile had a lower dementia and Alzheimer disease risk and persons in the second quartile had a lower DAS risk. The association between BMI anddementia resembled a U shape in those younger than 76 years, while dementiarisk decreased with higher BMI in those 76 years and older. The fourth quartile of waist circumference was related to a higher DAS risk in the whole sample, and todementia and Alzheimer disease in persons younger than 76 years. Weight loss was related to a higher dementia and DAS risk, and weight gain was related to a higher DAS risk only.

6. Etc.

Treatments of Obesity and Dementia
1. In a study of "Strength training as a countermeasure to aging muscle and chronic disease?" by Hurley BF, Hanson ED, Sheaff AK., posted in PubMed, researchers wrote that There is no evidence that ST can reverse any of the major biological or behavioural outcomes of Alzheimer's disease, but there is evidence that the prevalence of this disease is inversely associated with muscle mass and strength. Some indicators of cognitive function may also improve with ST. Thus, ST is an effective countermeasure for some of the adverse effects experienced by patients of many chronic diseases, as discussed in this review.

2. According to the study of "[Course modifying therapy of Alzheimer'sdementia]" [Article in German] by Heneka MT., posted in PubMed, researchers found that the therapy of risk factors including arterial hypertension and obesity in midlife as well as a Mediterranean diet currently provides the highest chance of modifying the course of the disease.

3. In the abstract of "Gender differences in dementia risk factors" by Azad NA, Al Bugami M, Loy-English I., posted in PubMed, researchers found that It remains critical that large prospective clinical trials be designed to assess the effect of optimum management of vascular risk factors on cognitive functioning anddementia as the primary outcome, and include women and men in numbers adequate for assessment of gender effects.

4.Etc.

The Obesity's Weight Loss Recipes: Kale salad

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Best Vegan Weight Loss  and Healthy Recipe, quoted from Raw food, volume 2, Healthy, delicious vegetarian cuisine made with living foods by Lisa Montgomery, editor, Hatherleigh

Dr. Scott and Raechelle Walker
Prep. 15 minutes
16 ounces organic Tuscan kale, chopped
1 cup diced cucumber
1 cup diced red pepper
1 cup broccoli florets
1 tsp. crushed garlic
1 cup Bragg's liquid aminos
1/2 cup extra virgin olive oil
Toss ingredients together and enjoy.




Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Gout: The Risk Factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

                                                            The  risk factors


1. Improper diet
If you body can not get rid uric acid quickly, intake foods with high levels of purine such as Alcohol, Beverages, Beer, Anchovies, Smelt, Fish, Eggs, Herring, Mackerel, Sardine, Sweetbread, Liver, Kidney, etc., is at increased risk of gout(7)(8)(10). Several dietary factors increased the risk of incident gout, including meat intake, seafood intake, sugar sweetened soft drinks, and consumption of foods high in fructose(10).

2. Alcohol consumption
Dr. Singh JA and scientists at the Birmingham VA Medical Centre, indicated, of the 751 titles and abstracts, 53 studies met the criteria and were included in the review. Several risk factors were studied. Alcohol consumption increased the risk of incident gout, especially beer and hard liquor(10)(7).
Others suggested that combined with their activities as urinate transporters and their strong associations with serum uric acid concentrations,

3. Medical conditions
Hypertension, renal insufficiency, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, diabetes are associated to increased risk of gout(10). Patient with Chronic kidney disease are at higher risk of gout as a result of Serum uric acid control in gout was poor among patients without CKD and even worse among those with CKD(11). Distinct group differences by content of uric acid seem to arise from early onset of chronic renal failure in women.

4. Medication
Gout is also drug-related(21). Thiazide and loop diuretics users are at increased risk of gout(12)(10), according to Johns Hopkins University Bloomberg School of Public Health.

5. Race
Some ethnic groups are particularly susceptible to gout, probaby due to genetic predisposition(13)(14).
6. Age and sex are associated to risk of the develop of gout(14)(15).

7. Genetics
GLUT9 and ABCG2 appeared to be important modulators of uric acid levels and likely of the risk of gout. Together with a growing list of environmental risk factors, these genetic data add considerably to our understanding of the pathogenesis of hyperuricemia and gout(16)(17)(19).

8. Family history
Accoridng to the total of 543 cases of juvenile gout from the Ho-Ping Gout Database, and 5269 gouty cases with onset age of 40 to 50 years, family history is associated to increased risk of gout(18)(19)
9. Obesity, over weight, weight change
Obesity and overweight are associated with a higher risk of incident gout and/or gout flare(10)(19).
Higher adiposity and weight gain are strong risk factors for gout in men, while weight loss is protective(5).

10. Menopause
Early menopause is associated with a higher risk of incident gout and/or gout flare(10). According to the16 years of follow-up (1 240 231 person-years), 1703 incident gout cases, conducted by the Taipei Municipal Hospital Gout Research Group, compared with premenopausal women, postmenopausal women had a higher risk of incident gout. Risk of gout is decreased among postmenopausal hormone users(22).

11. Recent surgery or trauma
According to Cleveland Clinic, risk of early postoperative gout is higher after bariatric surgery in comparison of patients undergoing other procedures(23)(24). There is a report of monoarticular gout following trauma in Medical College of Wisconsin literature(25).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(*) Musculoskeletal disorders and disability in persons aged 85 and over: a community survey. by van Schaardenburg D1, Van den Brande KJ, Ligthart GJ, Breedveld FC, Hazes JM.(PubMed)
(4) Tophi as first clinical sign of gout by Thissen CA1, Frank J, Lucker GP.(PubMed)
(7) [Hyperuricemia and gout; the role of diet].[Article in Spanish]by Álvarez-Lario B1, Alonso-Valdivielso JL2.(PubMed)
(8) A perspective on diet and gout by Kedar E1, Simkin PA.(PubMed)
(10) Risk factors for gout and prevention: a systematic review of the literature by Singh JA1, Reddy SG, Kundukulam J.(PubMed)
(11) Chronic kidney disease in gout in a managed care setting by Fuldeore MJ1, Riedel AA, Zarotsky V, Pandya BJ, Dabbous O, Krishnan E.(PubMed)
(12) Diuretic Use, Increased Serum Urate and the Risk of Incident Gout in a Population-based Study of Hypertensive Adults: the Atherosclerosis Risk in the Communities Cohort by Mara A. McAdams DeMarco, MS, PhD,1 Janet W. Maynard, MD, MHS,2 Alan N. Baer, MD,2 Allan C. Gelber, MD, MPH, PhD,1,2 J. Hunter Young, MD, MHS,1,3 Alvaro Alonso, MD, MPH, PhD,4 and Josef Coresh, MD, PhD1,3(PMC)
(13) Global epidemiology of gout: prevalence, incidence and risk factors by Kuo CF1, Grainge MJ2, Zhang W3, Doherty M3.(PubMed)
(14) Gout: a review of nonmodifiable and modifiable risk factors by MacFarlane LA1, Kim SC2.(PubMed)
(15) The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets by Rasheed H1,2, McKinney C1, Stamp LK3, Dalbeth N4, Topless RK1, Day R5,6, Kannangara D5,6, Williams K5,6, Smith M7, Janssen M8, Jansen TL9, Joosten LA10, Radstake TR11, Riches PL12, Tausche AK13, Lioté F14,15, Lu L16, Stahl EA17, Choi HK16, So A18, Merriman TR1.(PubMed)
(16) Genetics of gout by Choi HK1, Zhu Y, Mount DB.(PubMed)
(17) ABCG2/BCRP dysfunction as a major cause of gout by Matsuo H1, Takada T, Ichida K, Nakamura T, Nakayama A, Suzuki H, Hosoya T, Shinomiya N(PubMed)
(18) Juvenile gout in Taiwan associated with family history and overweight by Chen SY1, Shen ML.(PubMed)
(19) Clinical features of familial gout and effects of probable genetic association between gout and its related disorders by Chen SY1, Chen CL, Shen ML, Kamatani N.(PubMed)
(20) Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study by Choi HK1, Atkinson K, Karlson EW, Curhan G.(PubMed)
(21) Hyperuricaemia and gout by Shipley M1.(PubMed)
(22) Menopause, postmenopausal hormone use and risk of incident gout by Hak AE1, Curhan GC, Grodstein F, Choi HK.(PubMed)
(23) The effect of bariatric surgery on gout: a comparative study by Romero-Talamás H1, Daigle CR1, Aminian A1, Corcelles R1, Brethauer SA1, Schauer PR2.(PubMed)
(24) Development of acute gouty attack in the morbidly obese population after bariatric surgery by Antozzi P1, Soto F, Arias F, Carrodeguas L, Ropos T, Zundel N, Szomstein S, Rosenthal R.(PubMed)
(25) Monoarticular gout following trauma: MR appearance by Ruiz ME1, Erickson SJ, Carrera GF, Hanel DP, Smith MD.(PubMed)


The Obesity' Research and Studies of risk of postpartum hemorrhage in women using high dose of low-molecular-weight heparins during pregnancy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of risk of postpartum hemorrhage in women using high dose of low-molecular-weight heparins during pregnancy

In the evaluation to study the low-molecular-weight heparins (LMWH) are the most commonly used anticoagulant during pregnancy for prevention or treatment of VTE. However, the size of the associated risk of postpartum haemorrhage (PPH) is unknown conducted by University Medical Centre Groningen, Risk of PPH aftervaginal delivery was 30% and 18% for LMWH-users and non-users, respectively (OR 1.9, 95%CI 1.1-3.5). Risk of severe PPH after vaginal delivery was not different (5.6 vs 5.0%; OR 1.1; 0.4-3.6). Risk of PPH after CS was 12% in LMWH-users and 4% in non-users (OR 2.9; 0.5-19.4). Both events of LMWH-users occurred after emergency CS. The risk of PPH associated with delivery within 24 hours after last dose of LMWH was 1.2 fold higher (95%CI 0.4-3.6) compared to a larger interval.(1)

General Health: Detoxification - The 2nd Step to Detoxify Your Body - Understand Your Health Conditions

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The 2nd Step to Detoxify Your Body - Understand Your Health Conditions

American diet contains high saturated fat, trans fat, and other harmful substances such as sugar, caffeine, pesticides, additive substances, and less in fruits and vegetables. These types of harmful substances are toxic. Our body's detoxifying functions try to get rid of them everyday, when they fail it causes a disruption of hormone production, damaging our body's detoxification organs and weakening our immune system resulting in hormone imbalance and many chronic illness consequently. By the time you read this article, I hope that you already have followed the the first step and replaced your daily intake of food with healthier ones. Here is the second step, you might want to understand the most common diseases associated with an unhealthy diet.

1. High blood cholesterol level and triglyceride
Consuming a high amount of saturated fat and trans fat (a typical American diet) with less fruits and vegetables causes bad cholesterol building up in the arteries and triglyceride in the blood stream causing less oxygen in the blood and interfering with circulation of the blood as well as transportation of nutrients to our body's cells causing a variety of chronic illness.

2. High blood Pressure
The accumulation of bad cholesterol in the arteries and triglyceride in the bloodstream as well as deficiency of minerals causing calcium building up in the arterial wall resulting in arterial wall hardening and less elasticity. These types of problems cause the blockage of circulation of the blood. In order to provide more nutrients to our body's cells, our heart must work harder which results in high blood pressure and heart diseases.

3. Heart diseases
Heart diseases are caused by high blood pressure and other chronic diseases, mineral and nutritional deficiency such as diabetes, and magnesium, iron, and, zinc deficiencies. In this case, the heart has to work harder to provide oxygen and nutrients to the body's cells. If any go wrong in this process, we have coronary heart diseases.

3. Weakened Immune system
With poor diet that is high in fat, protein, less in fluids and vegetable, causes the clot up of arteries making the circulation of blood difficult for absorption of oxygen and nutrition to our body. Without enough nutrition, our body becomes weaker and easier to be infected by bacteria and virus as well as causing inflammation to our vital organs.

4. Mini Stroke
Not all mini stroke cause damage to our body, but thousand of mini strokes will. Mini stroke is a symptom of poor diet caused by arteries and blood vessels being clogged up by cholesterol and triglyceride. If any part of our brain's cells can not get enough oxygen the cells will die off and never come back, then we have stroke. Stroke might also be caused by a rupture of small blood vessels in the brain resulting in a hardened and less elastic brain vessels. This causes cells being covered by blood and unable receive oxygen provided.

5. ObesityOver 60% of the North American population are considered to be overweight according to the BMI index because of unhealthy diet with foods high in saturated fat and trans fat, less fruits and vegetables, and excessive drinking causing fat building in the abdominal area resulting in obesity and other forms of chronic diseases.

6. Diabetes
Diabetes is caused by receptors being clotted up by fat and cholesterol due to typical American diet with high saturated fat, trans fat, deficiency of minerals and vitamin, and becoming insensitive to insulin making it unable to enter the cells, resulting in high amounts of glucose remaining in the bloodstream and we have diabetes.

Most Common Diseases of 50 Plus - Upper gastrointestinal disorders: Gastro-esophageal reflux disease (GERD) - The Causes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


          Upper gastrointestinal (GI) diseases


The prevalence of upper gastrointestinal (GI) diseases is increasing in subjects aged 65 years and over. Pathophysiological changes in esophageal functions that occur with aging may, at least in part, be responsible for the high prevalence of
1. Gastro-esophageal reflux disease (GERD) in old age.

2. The incidence of gastric and duodenal ulcers and their bleeding complications is increasing in old-aged populations worldwide.

3. H. pylori infection in elderly patients with H. pylori-associated peptic ulcer disease and severe chronic gastritis.

4. Almost 40% of GU and 25% of DU in the elderly patients are associated with the use of NSAID(1) and/or aspirin(2).(a)

        Gastro-esophageal reflux disease (GERD)

Gastroesophageal reflux disease (GERD), also known as gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease, is defined as a chronic condition of liquid stomach acid refluxing back up from the stomach into the esophagus, causing heartburn. According to the study of “Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease.” by DeVault KR, Castell DO; American College of Gastroenterology, GERD is defined as symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus.

                                The Causes

1. Slower in emptying of the stomach after eating
Most uncommon causes of Gastroesophageal reflux disease (GERD) is due to the distention of the stomach with food over prolonged period of time that can lead to reflux. Approximately 20% of Gastroesophageal reflux disease (GERD) are caused the reason above. 

2. Cardia
Cardia is the area between the part of the stomach and the esophagus. It is angle where the esophagus enters the stomach and acts as a valve to prevent foods and others to reflux back to the esophagus. If the cardia is not functioning well, it can cause Gastroesophageal reflux disease (GERD with burning sensation of the esophagus. 

3. Esophageal contractile defection
If the esophageal contraction fails to performed its function of proper swallowing food, it may not generate enough waves of contractions to push the foods down to the stomach after swallowing and the acid back into the stomach. 

4. Hiatal hernia
Hiatal hernia is a condition of a portion of the stomach protrudes upward into the chest, through a tear or weakness in the diaphragm. According to the study of Nocturnal Reflux Episodes Following the Administration of a Standardized Meal. Does Timing Matter?Michael Piesman, M.D.; Inku Hwang, M.D.; Corinne Maydonovitch, B.S.; Roy K.H. Wong, M.D, posted in Medscape news Today, researchers found that GERD patients consuming a late-evening meal had significantly greater supine acid reflux compared to when they consumed an early meal, especially in overweight patients, and in patients with esophagitis or HH. These findings support the recommendations to our GERD patients to eat dinner early and to lose weight. 

5. Obesity
Obesity increase the risk of Gastroesophageal reflux disease (GERD). In a sudy of“The association between gastroesophageal reflux disease and obesity.” by Friedenberg FK, Xanthopoulos M, Foster GD, Richter JE., the authors wrote that weight loss, through caloric restriction and behavioral modification, has been studied infrequently as a means of improving reflux. Bariatric surgery and its effects on a number of obesity-related disorders have been studied more extensively. Roux-en-Y gastric bypass (RYGB) has been consistently associated with improvement in the symptoms and findings of GERD. 

6. Esophageal mucosa
In a study of “Halimeter ppb Levels as the Predictor of Erosive Gastroesophageal Reflux Disease.” by Kim JG, Kim YJ, Yoo SH, Lee SJ, Chung JW, Kim MH, Park DK, Hahm KB. posted in US National Library of Medicine National Institutes of Health, researchers found that Erosive changes in the esophageal mucosa were strongly associated with VSC levels, supporting the hypothesis that halitosis can be a potential biomarker for the discrimination between ERD and NERD, reflecting the presence of erosive change in the lower esophagogastric junction. 

7. Medication
The use of medication such as prednisolone acetate ophthalmic suspension, an adrenocortical steroid product can increase the risk of Gastroesophageal reflux disease (GERD). 

8. Chronic diseases
Chronic diseases, including cough, pulmonary fibrosis, earache, and asthma are also associated with the higher risk of develop Gastroesophageal reflux disease (GERD).

9. Infection
Infection caused by H. pylori can increase the risk of Gastroesophageal reflux disease (GERD). According to the study of “Helicobacter pylori infection and chronic gastric acid hyposecretion” by EM El-Omar, K Oien, A El-Nujumi, D Gillen, A Wirz, S Dahill, C Williams, JE Ardill, KE McColl posted in Gastroenterology, researchers concluded that in some subjects, chronic H. pylori infection produces a body-predominant gastritis and profound suppression of gastric acid secretion that is partially reversible with eradication therapy. (Gastroenterology 1997 Jul;113(1):15-24). 

10. Etc.