Medical Advisor Journals

Sunday, July 3, 2016

Anti Aging: The Research and Studies of Skin Aging - The Effects of Vitamins - E

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
All right reserved. Reproduction and Translation to other languages of this publication are prohibited without consent of the writer.

Who doesn't want to look 5, 10,15 or 20 years younger in comparison to people with the same age group?

The dream of finding the ingredients in rejuvenated aging skin has been ongoing since human civilization. Unfortunately, many ingredients with no commercial values have been discarded due to their effects in dampening the profits of all cosmetic companies.

Don't ask me about commercial anti-aging products. Most of them are produced for making profits and do not perform as theirs' claims. Truly, if one found to be effective, it will constitute to shelf-removal of many others with the same intention. Unfortunately, walking through the cosmetic section of health stores and super markets, thousands of these products are still packed on the shelves. How effective they are? You know the answer.

Skin aging is one of most visible process which occurs constantly in our skin organ. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals, to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin, affecting the skin elasticity and tightness(a). Other suggested that free radicals induced domino effects in production of reactive oxygen species, which can react with DNA, proteins, and fatty acids, causing oxidative damage and impairment of antioxidant system, resulting in injuries and damages regulation pathways of skin, including wrinkles, roughness, appearance of fine lines, lack of elasticity, and de- or hyperpigmentation marks(b).
Vitamin E, a fat soluble vitamin, consisting eight different variants (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) with varying levels of biological activity(2), found abundantly in corn oil, soybean oil, margarine, wheat germ oil, sunflower,safflower oils, etc. plays an important role in neurological functions and inhibition of platelet aggregation, regulation of enzymatic activity, free radical scavenger, etc..

Epidemiological studies, linking vitamin E in reduced progression of aging have been inconclusive(1)(2)(3)(4).

The effects
According to the Universiti Kebangsaan Malaysia, in stress-induced premature senescence (SIPS) model of human diploid fibroblasts (HDFs), γ-tocotrienol (GTT), a vitamin E variant showed to delay cellular senescence of human diploid fibroblasts through the inhibition of intrinsic mitochondria-mediated pathway which involved the regulation of pro- and anti-apoptotic genes and proteins(5) and prevented cellular aging in human diploid fibroblasts(6), probably through modulating gene expression(7) and protected against oxidative stress-induced cellular ageing by modulating the telomere length possibly via telomerase(8). The molecular mechanism of tocotrienol-rich fraction (TRF) study insisted that the variants protect against H(2)O(2)-induced oxidative stress in human skin fibroblast culture by modulating the expression of Skin Aging in COL I and COL III genes(Collagen gene) with concomitant increase in the rate of total collagen synthesis(9). According to the National University of Malaysia, f alpha-tocopherol (ATF), another variant of vitamin E protected against H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors(10) and topical administration of alpha-tocopherol (ATF), in medium doses, may provid some degree of photoprotection against UVA(11). Some researchers suggested the potent of vitamins in reduced aging progression is a result of the balance between various skin antioxidants of vitamin E and C, through new delivery systems, in delivering vitamins C and E into the skin simultaneously(12). Other antioxidant in improved skin health, includevitamin E, certain flavonoids, and the carotenoids, β-carotene, lycopene and lutein, may also effective through protection against inflammation, oxidative stress, breakdown of the extracellular matrix(13). In Indian women with facial signs ofaging study, the composition of niacinamide, panthenol, and tocopheryl acetate significantly reduced appearance of hyperpigmentation, improved skin tone evenness, appearance of lightening of skin, versus control in 6 weeks(14).

Taken altogether, composition of vitamin E and other antioxidants and its variants may be effective
in reduced early onset of skin aging and inhibited skin aging progression, but large sample size and multi centers studies to improve these validation are necessary. Over doses of vitamin E supplement can cause symptoms of blurred vision, weakness, dizziness, nausea, diarrhea, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies.

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References
(1) Evaluation of the photoprotective effect of oral vitamin E supplementation by Werninghaus K1, Meydani M, Bhawan J, Margolis R, Blumberg JB, Gilchrest BA.(PubMed)
(2) Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-alpha-tocopherol (vitamin E) by Eberlein-König B1, Placzek M, Przybilla B(PubMed)
(3) Effects of oral vitamin E and beta-carotene supplementation on ultraviolet radiation-induced oxidative stress in human skin by McArdle F1, Rhodes LE, Parslew RA, Close GL, Jack CI, Friedmann PS, Jackson MJ(PubMed)
(4) Effect of UV exposure and beta-carotene supplementation on delayed-type hypersensitivity response in healthy older men by Herraiz LA1, Hsieh WC, Parker RS, Swanson JE, Bendich A, Roe DA.(PubMed)
(5) Inhibition of mitochondrial cytochrome c release and suppression of caspases by gamma-tocotrienol prevent apoptosis and delay aging in stress-induced premature senescence of skin fibroblasts by Makpol S1, Abdul Rahim N, Hui CK, Ngah WZ(PubMed)
(6) Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts by Makpol S1, Zainuddin A, Chua KH, Yusof YA, Ngah WZ.(PubMed)
(7) Gamma-tocotrienol modulated gene expression in senescent human diploid fibroblasts as revealed by microarray analysis by Makpol S1, Zainuddin A, Chua KH, Mohd Yusof YA, Ngah WZ.(PubMed)
(8) Gamma-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals by Makpol S1, Abidin AZ, Sairin K, Mazlan M, Top GM, Ngah WZ.(PubMed)
(9) Modulation of collagen synthesis and its gene expression in human skinfibroblasts by tocotrienol-rich fraction by Makpol S1, Azura Jam F, Anum Mohd Yusof Y, Zurinah Wan Ngah W.(PubMed)
(10) Alpha-tocopherol modulates hydrogen peroxide-induced DNA damage and telomere shortening of human skin fibroblasts derived from differently aged individuals by Makpol S1, Zainuddin A, Rahim NA, Yusof YA, Ngah WZ.(PubMed)
(11) A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent by Evans-Johnson JA1, Garlick JA, Johnson EJ, Wang XD, Oliver Chen CY.(PubMed)
(11) Main approaches for delivering antioxidant vitamins through the skin to prevent skin ageing by Gašperlin M1, Gosenca M(PubMed)
(12) The role of phytonutrients in skin health by Evans JA1, Johnson EJ.(PubMed)
(14) The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: a randomized, double-blind trial by Jerajani HR1, Mizoguchi H, Li J, Whittenbarger DJ, Marmor MJ.(PubMed)

Women Health: Fibrocystic breast disease - Symptoms, Causes and Risk Factors

Fibrocystic breast disease also known as fibrocystic breast condition is defined as a condition in which cysts, and noncancerous lump found in the breast tissue as result of hormonal change from the menstrual cycle. Fibrocystic breast diseases sometime cause pain and discomfort which affects approximately 30-60% of women.

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The Symptoms

1. Lumps
As a result of the presence of fibrous tissue. Such lumps found nearby armpit, are smooth usually free-moving and become large before the menstrual cycle andwill slowly shrink when the cycle starts.
2. Breast pain
It may last through the whole cycle.
3. breast tenderness
As a result of the swollen breast tissue
4. Breasts and nipples may be tender or itchy.
5. Breast feel full
6. Etc.

The Causes and risk factors

1. Hormonal change
It is caused by hormonal change due to the normal hormonal variation during a woman's monthly cycle, as researchers that there are no such condition after menopause.

2. Family history of breast cancer
Some theories suggested that fibrocystic breast disease may be caused by family history in the direct family members. In a study of Cystic disease, family history of breast cancer, and use of oral contraceptives researchers found that the possibility that a woman is more protected against benign breast disease by using oral contraceptives if she has a family history of breast cancer deserves more attention in future investigations on the long-term effects of birth control pills.

3. Diet high in caffeine
Some theories suggested caffeine may be the cause but, in a study of Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study, researchers found that the association with caffeine consumption was especially high among women with atypical lobular hyperplasia and with sclerosing adenosis with concomitant papillomatosis or papillary hyperplasia, both of which have been associated with an increased breast cancer risk. The association was specific to fibrocystic breast disease in that there was no association of caffeine consumption with fibroadenoma or other forms of benign breast disease.

4. Diet high in unsaturated and trans fat
Intake high in unsaturated and trans fat elevates the production of estrogen, lower estrogen levels by eating fewer high-fat foods, especially from animal source will be helpful.

5. Colas and soda beverages
disturb the female hormones, so they should not be used in excess.

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General Health: Depression - the Preventive Supplements

The Preventive Supplements

1. DHEA
DHEA is the procusor for estrogen and testosterone, it helps to maintain mood, anxiety and menopausal women to have a better sense of well being and confident.

2. Chlorella
Chlorella contains high amounts of chlorophyll that not only help to prevent the forming of free radicals by aiding the moving of heavy metals that cause memory loss, increasing the phospholipid found on the surface of brain cell membrane resulting in delaying of memory loss and fending off the ravages of stress hormones.

3. Omega 3 fatty acid Omega-3 fatty acids play a crucial role in brain function as well as normal growth and development. Deficiency of Omega 3 includes extreme tiredness , poor memory, dry skin, heart problems, mood swings or depression .

4. L-cartinine
Amino acid acetyl L cartinine helps to regulate the hormone pregnenolone produced by the adrenal gland. Low levels of pregnenolone is associated with low energy, extreme tiredness and depression. Study shows that intake of amino acid acetyl L- cartinine helps to alleviate depression.

5. DMAE (Dimethylaminoethanol)
DMAE helps to stimulate the production of acetylcholine that helps to regulate the mood and energy level of our body and increase the ability of memory and learning.

6. Pumpkin seed extract
Pumpkin seed extract contains high amounts of zinc that helps to exhibit antidepressants such as stress suppresses brain-derived neurotrophic factor. Zinc also helps in promoting hormone balancing in our body by stimulating the production of growth hormones resulting in improve energy and well being.

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General Health: Acne and Acne Care

1. Acne care treatment: cream and lotion
Be sure before applying skin cream or lotion in acne effected area, wash it with mild soap and tepid water because water too hot or too cold might cause the breaking of capillaries (small veins). The best choice of acne cream and lotion is the one made by using ingredients of natural remedies that exist in the kitchen of your home for cost effectiveness and little or no side effect. You can find some acne formulas in this article. For convenience, there are plenty of acne creams and lotions in pharmacy drug stores. Be sure to choose one that does not contain chemicals causing side effects to your sensitive skin. Ask the pharmacist in the drug store which is the best approach. Please note that chemicals help to preserve the product might cause side effects to your sensitive skin.

2. Reducing the intake of saturated fat
Saturated fat intake causing the build up of cholesterol in capillaries, the small veins in your skin. Without giving enough oxygen to it, your skin becomes oily and easy to attract dirt, causing acne. To avoid this, you should substitute your red meat intake by 4- 8 servings every week with fish. They not only have good sources of protein as meat but also guards against the cholesterol build up in small veins in your skin.

3. Lower your body toxins
The system of toxins in your body exist in result of poor diet. If the liver and kidney are not able to get rid of these toxins completely, the skin becomes an extra burden to remove them, causing acne. To avoid this, adding some delicious antioxidants super-foods in your diet will help to solve this problem quickly such as garlic, ginger, etc.

4. Eat foods that purify your blood
Foods that help to purify your blood stream will increase the circulation of blood to your skin, helping the skin to become more healthy and immune from any skin problems such as acne. you can find these foods in these articles.
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General Health: Allergies - Dust Mite Allergy

Types of Allergy

Dust Mite Allergy is a defined as a condition caused by over reaction of immune system over the allergen of microscopic organism, found in house dust of all dwellings. In most case, dust mikes are found in warm, humid environments and bedding, upholstered furniture, carpeting, etc. According to statistic, dust mite, rye, ragweed, or cockroach caused allergic effects in approximately 25% of the population in US alone.

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D. 1. How to determine the severity of the allergic effects
Depending to the allergy stimulating effect, some researchers suggested to scalethe severity from 1 to 4 and followed by degeneration scale, but from -1 to -4
D.1.1. The severity scale from +1 to +4
+1. The first level of stimulation
If there is no symptoms at all or If the patient is alert and function morally after allergic is eaten
+2. The second level of stimulation
The patient have become irritable, hyperactive, tense, thirsty, etc. after a suspected allergic foods is eaten
+3. The third level of stimulation
The patient have become hypomanic, aggressive, apprehensive, etc.
+4. The fourth level of stimulation
The patient have become mania, agitation, over excitement, etc.

D.1.2. Degeneration scale from -1 to -4
-1. If a patient is experience symptoms of reaction of runny nose, hive, diarrhea, etc.
-2. If a patient is experience symptoms of reaction of tiredness, fatigue, swelling etc.
-3. If a patient is experience symptoms of reaction of depression, mental disturbance, confusion, mood change, etc.
-4. If a patient is experience symptoms of reaction of sever depression, paranoia, etc.

D.2. Risk factors
1. Family history
Increased risk of Dust Mite Allergy for people who have a family history of the disease.
2. Exposure
Risk of dust mike allergy increases if you are exposed to high levels of dust mites in a young age.
3. Age
Childhood or young adult are at higher risk of the disease.
4. Etc.

D.3. Symptoms
1, Asthma in sever case
In a study of "House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program." by Huss K, Adkinson NF Jr, Eggleston PA, Dawson C, Van Natta ML, Hamilton RG. (Johns Hopkins Asthma and Allergy Center, Baltimore, MD, USA.) posted in US National Library of Medicine National Institutes of Health, researchers found that levels of exposure determined by house dust analysis are important determinants of sensitization for dust mite and cockroach allergen. This relationship was not demonstrable for cat, dog, or mold allergens, possibly because of confounding factors. For all allergens studied, the degree of atopy, determined by the total number of positive skin test responses or by total serum IgE levels, is an important contributing risk factor for sensitization.

a. Breathing difficult
b. Air way tighten
c. Whistling or wheezing sound when breath
d. Etc.
2. Other mild common symptoms include
a. Sneezing
b. Itchy nose, roof of mouth or throat
c. Runny nose
d. Nasal congestion
e. Itchy, red or watery eyes
f. Cough
g. Etc.

D.4. Diagnosis
If you are experience Dust Mite Allergy, After recording the family history and a complete physical exam. you doctor may order
1. Skin test
a. Intradermal test
It is one of most common test but time consuming( some patient may return for more 20 time for the injection) in diagnosis of allergy and depending to the symptoms, by injecting small amounts of diluted allergens into the top layers of the skin to see how the immune system react to them.
b. Skin prick testing
Similar to the Intradermal test, but the diagnosis involves in applying a drop of allergen into to punctures made on the skin.

2. Blood test ((RadioAllergoSorbent Test)
This is the test for evaluating of the levels of IgE-mediated food allergies react to a particular allergen. If you RAST score is higher than the predictive value for that food, 95% chance you will have an allergic reaction. Unfortunately, non-IgE mediated allergies cannot be detected by this method.

5. Challenge Tests
Because of the risk of anaphylaxis, most doctors will avoid the test unless it is absolutely necessary. The test is performed only in the hospital. In this test, suspected allergen package into capsule taken by patient and signs or symptoms of an allergic reaction are observed.

5. Etc.

D.5. Prevention
In general, if we can keep our home clean and reduce the accumulation of dust and not suitable environment for the pests, we can decrease the risk of dust mike allergy.

D.6. Treatments
D.6.1. Conventional medicine
1. There is no specific treatment for Dust Mite Allergy, but depending to the symptoms. Medication includes bronchodilators, anti-allergics, antihistamines,NSAIDs, etc.
2. Allergic shot
Allergy shot, also known as immunotherapy, contains extracts from the most common substance which people are allergic to, including pollen, insects, pets, Dust Mite, etc., by providing long-term relief from certain symptoms. In some people, after series of allergic shot, the disease is cured.

D.6.2. Nutritional supplements
1. Antioxidants
Since Allergies are caused by immune over reaction of certain harmless substance, enhancing immune system is one of the best way to prevent and treat them as some researchers suggested that allergies may be caused by over aggression of a weakened immune system.. Vitamin A, E, C are antioxidants and free radical scavengers, they protect the immune system from free radicals attack and help to reduce levels of histamine in the blood. For more information ofantioxidants and health effects

2. Vitamin D
According to the article " Vitamin D deficiency may be a factor in development of allergies posted in Washing Post, Monday, March, 7, 2011, " Allergies and Vitamin D, Youths low in 'sunshine vitamin' may be more prone to allergies",the author wrote that analyzed data on 6,590 people, roughly half of them 21 years of age and younger and half older. The group was deemed representative of the U.S. population. Vitamin D levels were determined by blood tests, as was sensitivity to 17 common allergens. Among the youths, food and environmental allergies were greater in those with lower levels of Vitamin D. Young people deficient in Vitamin D were about twice as likely as those with higher levels of the nutrient to have peanut or ragweed allergies and nearly five times as likely to be allergic to oak.

3. B-complex
in a study of "Vitamin B-6 deficiency impairs interleukin 2 production and lymphocyte proliferation in elderly adults." by Meydani SN, Ribaya-Mercado JD, Russell RM, Sahyoun N, Morrow FD, Gershoff SN., USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111. posted in US National Library of Medicine National Institutes of Health, researchers found that Vitamin B-6 deficiency impairs in vitro indices of cell-mediated immunity in healthy elderly adults. This impairment is reversible by vitamin B-6 repletion.

4. N-accetyl-cysteine (NAC)
It is an antioxidant and an amino acid precursor to glutathione which helps to strengthen immune system against cold, flu and allergy and enhances the respiratory system functioning.

5. Coenzyme Q10
It is an immune and nervous system enhancer, according to the article of "CoQ10 Helps the Immune System and Brain Function" by A.S. Gissen, posted in Immunesupport.com, the author wrote that In 1970, it was first reported that CoQ6 and CoQ10, when administered to rats, significantly enhanced immune cells' ability to kill bacteria, as well as elevated their antibody response.

6. Alpha lipoic acid
Alpha lipoic acid is another antioxidant which promotes the immune system by enhabcing the function of other antioxidants such as vitamin C, E, glutathione, etc. according to the article of "A relatively unknown antioxidant, alpha-lipoic acid, may be more potent than vitamins C and E" by Robert Sander, the author wrote that Because both alpha-lipoic acid and dihydrolipoic acid are antioxidants, their combined actions give them greater antioxidant potency than any natural antioxidant now known, Packer says. He notes another property of alpha-lipoic acid that makes it a great antioxidant. Since it is soluble in both water and fat, it can move into all parts of the cell to neutralize free radicals. Vitamin C, on the other hand, is limited to the watery parts of cells because it is soluble only in water; while vitamin E is soluble only in fat and sticks to the fatty parts of cells.
7. Minerals
a. Calcium
It beside is considered as essential mineral for healthy bone, calcium is also important to reduce the risk of allergy. According to the study of "Calcium-deficiency rickets in a four-year-old boy with milk allergy." by Davidovits M, Levy Y, Avramovitz T, Eisenstein B.(Nephrology Unit, Children's Medical Center, Petah Tiqva, Israel) posted in US National Library of Medicine National Institutes of Health, researchers found that These findings were thought to be the result of dietary calcium deficiency caused by the prolonged elimination from his diet of cow milk and milk products because of allergy. Adequate intake of calcium resulted in rapid improvement.

c. Potassium
It enhance the adrenal gland function, thus reducing the symptoms of allergy cause of fatigue, weakness, tiredness
d. Magnesium
It is vital to relieve the allergy symptom of asthma and respiratory problems.
e. Etc.

10. Etc.

D.6.3. Herbs
1. Ginkgo
Ginkgo leaves contain ginkgolides, which inhibit platelet-activating factor cause of asthma and allergies. according to the study of "Ginkgolides Antagonizing Some Effects of Platelet-activating Factor in Vitro" vy Dong JC, Li M, Shi ZY (Huashan Hospital, Shanghai Medical University) posted in Chiro.org, researchers found thatexposure of guinea pigs' bronchus to PAF in vitro resulted in a loss of beta-adrenergic receptors and responses to isoproterenol, and this effect of PAF was prevented by prior incubation of the guinea pigs' bronchus with ginkgolides (P < 0.05). The results showed ginkgolides were a potent PAF antagonist.

2. Panax Ginseng
In a study of "Effects of Red Ginseng extract on allergic reactions to food in Balb/c mice." by

Sumiyoshi M, Sakanaka M, Kimura Y. (Division of Functional Histology, Department of Functional Biomedicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.) posted in US National Library of Medicine National Institutes of Health, researchers suggested that It may also protect against sensitization to antigens as an immunomodulator by increasing intestinal IgA secretion without affecting antigen-specific IgE levels. In conclusion, Red Ginseng roots may be a natural preventative of food allergies.

3. Garlic
It is best known for treating cold and flu and enhances immune system against alll types of foreign invasion. According to the study of "Immunomodulatory Effects of Aged Garlic Extract"
Eikai Kyo, Naoto Uda, Shigeo Kasuga and Yoichi Itakur, Posted in the "Journal of Nutrition" in March 2001, researchers strongly suggest that AGE (Aged Garlic Extract) could be a promising candidate as an immune modifier, which maintains the homeostasis of immune functions; further studies are warranted to determine when it is most beneficial.

4. Grape seed extract

Grape seed extract is best known for its antioxidant property in delay aging, it also acts as a natural histamine inhibitor, thus reducing the risk of allergic responses.

5. Turmeric
Turmeric paste has been used in traditional herbal medicine as an antimicrobial and anti-inflammatory agent, it also helps to treat allergy. According to an article "Vitamin D and turmeric for allergies" by Joe Graedon and Teresa Graedon posted in Washington Post, May 11-2009, the authors wrote that In animal studies, turmeric prevents the release of histamine from mast cells (Molecular Nutrition and Food Research, September 2008). If it works similarly in humans, this would prevent allergy symptoms from developing.

6. Licorice root

Beside is nest known to lower stomach acid levels, relieve heartburn and indigestion, licorice root is also boost the levels of interferon of immune system to fight off attacking viruses. According to the article of "Licorice, plantain and nettle herbs used in the treatment of Allergies" posted in Bitteroot restorationthe author wrote that This ( Licorice root) can actually help to counteract many of the symptoms that are associated with allergies.: It also contains substances which work to thin the mucus and soothe to respiratory passages, which can reduce irritation that often accompanies allergies and their symptoms.

7. Etc.

D.6.4. Traditional Chinese medicine
Xin Yi Hua is a lily-shaped flower with a hairy bud and Xin-yi-san (Magnolia Flower Powder)
a. It is a type of traditional Chinese medicine used to treat allergy and dramatically reduces the symptoms of sneezing, anosmia, nasal congestion and profuse rhinorrhea (runny nose) caused by allergies triggered by dust mites, pets and fungi.
According to the study of "Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects" by
Sien-Hung Yang, Chia-Li Yu, Ying-Lin Chen, Sheng-Lin Chiao, Mei-Ling Chen f. Posted in International Immunopharmacology 10 (2010) 951–958, researchers found that this proposal is based on the fact that different combinations of Chinese herbs involve different mechanisms. It appears that the immunosuppressive and anti-inflammatory effects derived from the mixed formula of Chinese herbs are broader than XYS. Nevertheless,we found that XYS alone sufficiently exerts immunomodulatory effects on patients with AR.
In conclusion, this study provides evidence to support that XYS, when used singly, is beneficial in nasal allergic inflammation throughenhancing IL-10 and IL-8 production.
b. Ingredient
Main use: Expels wind-cold, unblocks nasal passages, congestion, loss of smell, sinus headache.Chinese Food Therapy
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The Obesity' Research and Studies of Diet, insulin resistance, and obesity: data for Atkins dieters

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Diet, insulin resistance, and obesity: data for Atkins dieters

In the study to evaluate dietary interventions regarding their safety and metabolic effects, indicated that these high-fat diets have been shown to be safe in the short term; however, their long-term safety has not been established. With respect to insulin sensitivity, diets enriched in saturated fats can induce insulin resistance, whereas fat substitution with monounsaturated fats can enhance insulin sensitivity. On the other hand, high-fiber, high-carbohydrate diets comprised of foods with low caloric density can similarly be used for effective weight reduction and to ameliorate insulin resistance. Although some data suggest that low-glycemic index diets are most advantageous in this regard, these effects may have more to do with increments in dietary fiber than differences in available carbohydrates. Popular low-carbohydrate, high-fat diets are being fervently embraced as an alternative to challenging modifications in lifestyle and intentional calorie reduction. Current data do not support such unbridled enthusiasm for these diets, particularly in relationship to high-fiber, high-carbohydrate diets emphasizing intake of fresh vegetables and fruits(1).

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The Best Way to prevent, treat your disease, including Obesity
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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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(1) "Diet, insulin resistance, and obesity: zoning in on data for Atkins dieters living in South Beach" by Lara-Castro C, Garvey WT.