Medical Advisor Journals

Tuesday, July 5, 2016

Phytochemicals in Foods - The Effects of Cryptoxanthin

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cryptoxanthin

Cryptoxanthin is a phytochemincal of Yellow pigments in the class of Xanthophylls , belonging to the group of Carotenoids (tetraterpenoids), found abundantly in orange, papaya, peaches, avocado, pea, grapefruit, kiwi, etc.

Health Benefits
1. Antioxidant effects
In the investigation of the biological properties of beta-cryptoxanthin, a common carotenoid, in cell culture model systems, using the comet assay to measure DNA damage, found that At low concentrations, close to those found in plasma, beta-cryptoxanthin does not itself cause damage, but protects transformed human cells (HeLa and Caco-2) from damage induced by H(2)O(2) or by visible light in the presence of a photosensitizer. In addition, it has a striking effect on DNA repair, measured in different ways. Incubation of H(2)O(2)-treated cells with beta-cryptoxanthin led to a doubling of the rate of rejoining of strand breaks and had a similar effect on the rate of removal of oxidized purines by base excision repair, according to "The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells" by Lorenzo Y, Azqueta A, Luna L, Bonilla F, Domínguez G, Collins AR.(1)

2. Anti cancers
In the demonstration of CHRP and/or MJs (a pulp (CHRP) and citrus juices (MJ2 and MJ5) from a satsuma mandarin (Citrus unshiu Mar.) juice (MJ)) and theirs effects on rat colon, rat tongue, and mouse lung tumorigenesis,m found that gavage with CHRP resulted in an increase of activities of detoxifying enzymes in the liver, colon, and tongue rats'. CHRP and MJs were also able to suppress the expression of proinflammatory cytokines and inflammatory enzymes in the target tissues. This paper describes the findings of our in vivo preclinical experiments to develop a strategy for cancer chemoprevention of colon, tongue, and lung neoplasms by use of CHRP and MJs, according to "Cancer chemoprevention by citrus pulp and juices containing high amounts of β-cryptoxanthin and hesperidin" by Tanaka T, Tanaka T, Tanaka M, Kuno T.(2)

3. Pulmonary tumorigenesis
In the investigation of the inhibitory effect of mandarin juice rich in beta-cryptoxanthin and hesperidin on lung cancer, found that treatments with MJ, MJ2, and MJ5 reduced the incidence of lung tumors and the inhibition by MJ5 (29% reduction) was statistically significant (P<0.05). MJs treatment lowered the multiplicity of lung neoplasms without statistical significance. Immunohistochemically, MJs, especially MJ5, reduced proliferating cell nuclear antigen (PCNA)-positive index in the lung tumors without affecting PCNA index in hyperplastic alveolar cell lesions, according to "Inhibitory effect of mandarin juice rich in beta-cryptoxanthin and hesperidin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary tumorigenesis in mice" by Kohno H, Taima M, Sumida T, Azuma Y, Ogawa H, Tanaka T.(3)

4. Renal cell carcinoma
In the assessment of the association between renal cell cancer (RCC) and intake of fruit, vegetables and nutrients examined in a population-based case-control study of 323 cases and 1827 controls; dietary intake was obtained using a mailed questionnaire, found that β-Cryptoxanthin and lycopene were also associated with decreased risks, but when both were included in a mutually adjusted backwards stepwise regression model, only β-cryptoxanthin remained significant (OR 0·5; 95 % CI 0·3, 0·8). When other micronutrients and types of fibre were investigated together, only vegetable fibre and β-cryptoxanthin had significant trends (P < 0·01) (OR 0·6; 95 % CI 0·3, 0·9) (OR 0·5; 95 % CI 0·3, 0·9), respectively, according to "Fruit, vegetables, fibre and micronutrients and risk of US renal cell carcinoma" by Brock KE, Ke L, Gridley G, Chiu BC, Ershow AG, Lynch CF, Graubard BI, Cantor KP.(4)

5. Adiposity
In the identification of Oral administration of β-CRX and the effect on the mechanism, obese model mouse, TSOD used in the study, found that DNA microarray analysis strongly indicates that the oral administration of β-CRX represses the inflammatory cytokine secretion and improves the lipid metabolism and the energy consumption. It also suggests these effects are partly mediated by PPAR-α, not only lipid metabolism and adipocyte differentiation control but possibly internal circadian clock modulation, according to "Prevention of Adiposity by the Oral Administration of β-Cryptoxanthin" by Takayanagi K.(5)

6. Non-Hodgkin lymphoma (NHL)
In the evaluation of the potential association between consumption of fruit and vegetables and non-Hodgkin lymphoma (NHL) by histologic, indicated that for nutrients, the risk of NHL overall was inversely associated with a higher intake of β-cryptoxanthin (OR = 0.6; CI = 0.4-0.9), magnesium (OR = 0.4; CI = 0.2-0.6), potassium (OR = 0.5; CI = 0.3-1.0), and fiber (OR = 0.6; CI = 0.3-1.0), but positively associated with a higher intake of retinol (OR = 1.7; CI = 1.1-2.8). Intakes of vitamin E, magnesium, and potassium were inversely associated with the risk of DLBCL, according to "Dietary intake of fruit and vegetables and risk of non-Hodgkin lymphoma" by Chiu BC, Kwon S, Evens AM, Surawicz T, Smith SM, Weisenburger DD.(6)

7. Anti lung inflammation, oxidative damage, and squamous metaplasia
In the evaluation of the effects of β-cryptoxanthin supplementation on cigarette smoke-induced squamous metaplasia, inflammation, and changes in protein levels of proinflammatory cytokine [tumor necrosis factor alpha (TNFα)] and transcription factors [nuclear factor kappa B (NF-κB) and activator protein-1 (AP-1)], as well as on smoke-induced oxidative DNA damage [8-hydroxy-2'-deoxyguanosine (8-OHdG)] in the lung tissue of ferrets, found that β-Cryptoxanthin supplementation dose-dependently increased plasma and lung β-cryptoxanthin levels in ferrets, whereas cigarette smoke exposure lowered plasma and lung β-cryptoxanthinlevels. β-Cryptoxanthin at both doses significantly decreased smoke-induced lung squamous metaplasia and inflammation. β-Cryptoxanthin also substantially reduced smoke-elevated TNFα levels in alveolar, bronchial, bronchiolar, and bronchial serous/mucous gland epithelial cells and in lung macrophages. Moreover, β-cryptoxanthin decreased smoke-induced activation of NF-κB, expression of AP-1 and levels of 8-OHdG. The beneficial effects of β-cryptoxanthin were stronger for high-dose β-cryptoxanthin than for low-dose β-cryptoxanthin, according to "β-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage, and squamous metaplasia in ferrets" by Liu C, Bronson RT, Russell RM, Wang XD.(7)

8. Insulin resistance
In the investigation of a fat-soluble extract from persimmon peel (PP) and fed type 2 diabetic Goto-Kakizaki (GK) rats an AIN-93G rodent diet supplemented with persimmon peel extract (PP diet) for 12 weeks, found that compared with the control AIN-93G diet, the PP diet significantly reduced plasma glutamic-pyruvate transaminase activity, with accumulation of β-cryptoxanthin in the liver. DNA microarray analysis revealed that the PP diet altered hepatic gene expression profiles. In particular, expression of insulin signaling pathway-related genes was significantly enriched in differentially expressed gene sets. Moreover, Western blotting analysis showed an increase in insulin receptor beta tyrosine phosphorylation in rats fed the PP diet, according to "Hepatic gene expression of the insulin signaling pathway is altered by administration of persimmon peel extract: a DNA microarray study using type 2 diabetic Goto-Kakizaki rats" by Izuchi R, Nakai Y, Takahashi H, Ushiama S, Okada S, Misaka T, Abe K.(8)

9. Anti Breast cancer
In the study consisting of 604 breast cancer cases and 626 controls with prospectively measured circulating carotenoid levels and mammographic density in the Nurses' Health Study,
found that no evidence that circulating carotenoids are inversely associated with mammographic density. However, mammographic density significantly modified the association between total circulating carotenoids and breast cancer (P heterogeneity = 0.008). Overall, circulating total carotenoids were inversely associated with breast cancer risk (P trend = 0.01). Among women in the highest tertile of mammographic density, total carotenoids were associated with a 50% reduction in breast cancer risk (odds ratio, 0.5; 95% confidence interval, 0.3-0.8). In contrast, there was no inverse association between carotenoids and breast cancer risk among women with low mammographic density. Similarly, among women in the highest tertile of mammographic density, high levels of circulating alpha-carotene, beta-cryptoxanthin, lycopene, and lutein/zeaxanthin were associated with a significant 40% to 50% reduction in breast cancer risk (P trend < 0.05), according to "Circulating carotenoids, mammographic density, and subsequent risk of breast cancer" by Tamimi RM, Colditz GA, Hankinson SE.(9)

10. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19056931
(2) http://www.ncbi.nlm.nih.gov/pubmed/22174562
(3) http://www.ncbi.nlm.nih.gov/pubmed/11689289
(4) http://www.ncbi.nlm.nih.gov/pubmed/22186835
(5) http://www.ncbi.nlm.nih.gov/pubmed/22131983
(6) http://www.ncbi.nlm.nih.gov/pubmed/21695384
(7) http://www.ncbi.nlm.nih.gov/pubmed/21421799
(8) http://www.ncbi.nlm.nih.gov/pubmed/21370910
(9) http://www.ncbi.nlm.nih.gov/pubmed/19934322

Anti Aging: The Research and Studies of Skin Aging - The Effects of Vitamins - B5

Vitamin B5, also known as Pantothenic acid, is a water-soluble vitamin found abundantly in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado, and yogurt. The vitamin plays an important role in synthesized and metabolized proteins, carbohydrates, and fats.

According to 1Nutrition Science Solutions LLC, in the study of Hass avocados, containing high amounts of pantothenic acid and other antioxidants, showed a positive effect in supported cardiovascular health and might support weight management and healthy aging(1). A facial lotion containing vitamins B3 and E and provitamin B5, showed a significantly reduced appearance of hyperpigmentation, improved skin tone evenness, appearance of lightening ofskin in a total of 246 women randomized to treatment, 207 (84%) completed the study(2). Panthenyl triacetate, a Water- and oil-soluble derivative of pantothenic acid (vitamin B5) used combination with Ethyl linoleate (bioactive complex) and given both pre- and post-irradiation, showed to stimulate the repairing enzyme expression caused by skin photo-ageing induced accumulation of oxidized protein(3). Composition of Dead Sea (DS) mud and other ingredients like DS water, zinc oxide, aloe-vera extract, pro-vitamin B5 and vitamin E, exhibited its protective, anti-oxidant and anti-inflammatory properties antagonized biological effects of UVB irradiation in skin(4). Topical application of Dexpanthenol, asupplemental source of pantothetic acid considerably improved the symptoms ofskin irritation, such as dryness of the skin, roughness, scaling, pruritus, erythema, erosion/fissures, over 3 to 4 weeks, according to the study by 1Technical University of Munich, Allershausen(5) and enhanced skin barrier repair and stratum corneum hydration, while reduced skin roughness and inflammation(6).

Taken altogether, vitamin B5 may be effective in reduced the onset of skin aging and aging progression through its antioxidant activity, but further studies are necessary to confirm its claim. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & Related field specialist before applying.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(a) Skin ageing: natural weapons and strategies by Binic I1, Lazarevic V, Ljubenovic M, Mojsa J, Sokolovic D.(PubMed)
(b) Phytoconstituents as photoprotective novel cosmetic formulations by Saraf S1, Kaur CD.(PubMed)
(1) Hass avocado composition and potential health effects by Dreher ML1, Davenport AJ.(PubMed)
(2) The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: a randomized, double-blind trial by Jerajani HR1, Mizoguchi H, Li J, Whittenbarger DJ, Marmor MJ(PubMed)
(3) A bioactive complex to protect proteins from UV-induced oxidation in human epidermis, by Schweikert K1, Gafner F, Dell'Acqua G.(PubMed)
(4) Protective effects of a cream containing Dead Sea minerals against UVB-induced stress in human skin by Portugal-Cohen M1, Soroka Y, Ma'or Z, Oron M, Zioni T, Brégégère FM, Neuman R, Kohen R, Milner Y.(PubMed)
(5) Topical use of dexpanthenol in skin disorders by Ebner F1, Heller A, Rippke F, Tausch I.(PubMed)
(6) Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation by Proksch E1, Nissen HP.(PubMed)

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: TCM Foods Suggestion for Kidney Yin deficiency - Organic soy products and whole food

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into

Kidney yin deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yin deficiency may also experience yin vacuity induced cold expressive syndrome, including soreness of waist and knees(1848), lassitude(1848) and fatigue(1848), short breath(1848), poor appetite(1848), aversion to cold(184), cold extremities(1848), ringing in the ears(1850), migraine(1849), hearing problems(1850), a dry mouth and throat(1851), pale fingernails(1851), tidal fever(1851)and night sweating(1851), soles(1851) and chest(1851), constipation(1852),,......... as the kidneys no longer perform their functions of regulating fluid in moistening and nourishing organs and tissues of the body. According to TCM, too much cold/raw foods can aggravate the condition.

In the review of the Data base provided by PubMed, kidney yin deficiency may induce functional impairment or metabolic derangements in vital organs/tissues(1853) persuaded a conglomeration of sundry chronic disease state(1853), cognitive dysfunction(1854), vasomotor symptoms(1855),..... leading to accumulation of fluid in the body organ, promoted accentuation of inflammatory development of phlegm.
Kidney yin deficiency has shown to alter amino acid metabolism(1856), energy metabolism(1856) and gut microflora(1856), anovulatory infertility(1857) and
hypertension(1858), hyperinsulinemia(1859) and hyperandrogenia(1859)..... of which related to symptoms of PCOs(1859).

Foods for Kidney yin deficiency

List of foods suggested by TCM doctors for management and treatment of PCOs' women diagnosed with kidney yin deficiency, including

4. Organic soy products and whole food
Made from organic soy bean has induced many controversies due to conflict of Western cancer studies. Readers in the Western world should consult their caregivers before taking any of these products.
Soybean is genus Glycine, the family Fabaceae, one of the legumes that contains twice as much protein per acre as any other major vegetable or grain crop, native to Southeast Asia. Now, it is grown worldwide massively in suitable climate for commercial profit and a a healthy foods(1873). According to GMO compass, in 2113, 79% of soybean production were genetic modified(1874).

Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Essential amino acid
6. Vitamin A
7. Vitamin B6
8. Vitamin B12
9. Vitamin C
10. Vitamin K
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc
18. Etc.

According to the data base from PubMed, organic soy bean has shown to inhibit certain effects in metabolic syndrome, including hypertension(1875)(1884), hypercholesterolemia(1875)(1876)(1877), dyslipidemia(1878)(1884) inflammation(1875)(1883), insulin resistance(1876)(1884), impaired fasting glucose(1880)(1881), prediabetes(1884)(1885), hyperglycerolemia(1887), weight control(1888)(1889) and obesity(1876)(1886) as well as reduced risk of diabetes(1885) and cardiovascular disease(1875)(1877)(1892), probably due to its protein(1876) and phytochemicals(1883)(1893) effects on lipid(1890)(1891)(1893) and glucose(1893) metabolism andin regulation of insulin-mediated glucose homeostasis in adipose tissue(1882).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
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(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
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(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
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(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
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(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
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(1873) Healthy Foods- Soybeans (Glycine) by Kyle J. Norton
(1874) Genetically modified plants: Global Cultivation Area Soybean(GMO compass)
(1875) Effect of soy nuts and equol status on blood pressure, lipids and inflammation in postmenopausal women stratified by metabolic syndrome status by Acharjee S1, Zhou JR2, Elajami TK1, Welty FK3.(PubMed)
(1876) Partly replacing meat protein with soy protein alters insulin resistance and blood lipids in postmenopausal women with abdominal obesity by van Nielen M1, Feskens EJ1, Rietman A1, Siebelink E1, Mensink M2.(PubMed)
(1877) Effect of soy protein from differently processed products on cardiovascular disease risk factors and vascular endothelial function in hypercholesterolemic subject by Matthan NR1, Jalbert SM, Ausman LM, Kuvin JT, Karas RH, Lichtenstein AH.(PubMed)
(1878) The effects of a diet formulation with oats, soybeans, and flax on lipid profiles and uricemia in patients with AIDS and dyslipidemia by Ferreira Rdos S1, Cassaro DC2, Domingos H3, Pontes ER4, Aiko PH4, Meira JE5.(PubMed)
(1879) Dietary patterns and cardiovascular disease-related risks in chinese older adults by Sun J1, Buys N1, Shen S2.(PubMed)
(1880) A meal replacement regimen improves blood glucose levels in prediabetic healthy individuals with impaired fasting glucose by König D1, Kookhan S2, Schaffner D2, Deibert P3, Berg A2.(PubMed)
(1881) Oral administration of soybean peptide Vglycin normalizes fasting glucose and restores impaired pancreatic function in Type 2 diabetic Wistar rats by Jiang H1, Feng J2, Du Z1, Zhen H3, Lin M2, Jia S4, Li T5, Huang X6, Ostenson CG7, Chen Z8.(PubMed)
(1882) Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue. Wang M1, Gao XJ, Zhao WW, Zhao WJ, Jiang CH, Huang F, Kou JP, Liu BL, Liu K.(PubMed)
(1883) Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers by Ferguson JF1, Ryan MF2, Gibney ER2, Brennan L2, Roche HM3, Reilly MP4.(PubMed)
(1884) The beneficial effect of soybean (Glycine max (L.) Merr.) leaf extracts in adults with prediabetes: a randomized placebo controlled trial by Choi MS1, Ryu R, Seo YR, Jeong TS, Shin DH, Park YB, Kim SR, Jung UJ.(PubMed)
(1885)Equol producers can have low leptin levels among prediabetic and diabetic females by Sakane N1, Kotani K2, Tsuzaki K3, Takahashi K4, Usui T5, Uchiyama S6, Fujiwara S7.(PubMed)
(1886) Obesity prevalence in relation to gut microbial environments capable of producing equol or O-desmethylangolensin from the isoflavone daidzein by Frankenfeld CL1, Atkinson C2, Wähälä K3, Lampe JW4.(PubMed)
(1887) Effect of soy product kinako and fish oil on serum lipids and glucose metabolism in women with metabolic syndrome by Simão AN1, Lozovoy MA, Dichi I.(PubMed)
(1888) Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial by Neacsu M1, Fyfe C1, Horgan G1, Johnstone AM1.(PubMed)
(1889) Soy fiber improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial by Hu X1, Gao J, Zhang Q, Fu Y, Li K, Zhu S, Li D.(PubMed)
(1890) Effects of soya oligosaccharides and soya oligopeptides on lipid metabolism in hyperlipidaemic rats by Xie S1, Zhu J, Zhang Y, Shi K, Shi Y, Ma X.(PubMed)
(1891) Effects of dietary plant meal and soya-saponin supplementation on intestinal and hepatic lipid droplet accumulation, lipoprotein and sterol metabolism in Atlantic salmon (Salmo salar L.) - CORRIGENDUM. Gu M, Kortner TM, Penn M, Hansen AK, Krogdahl A.(PubMed)
(1892) Soy food consumption, cardiometabolic alterations and carotid intima-media thickness in Chinese adults by Liu J1, Sun LL1, He LP2, Ling WH1, Liu ZM3, Chen YM4.(PubMed)
(1893) Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production by Hall WL1, Vafeiadou K, Hallund J, Bugel S, Reimann M, Koebnick C, Zunft HJ, Ferrari M, Branca F, Dadd T, Talbot D, Powell J, Minihane AM, Cassidy A, Nilsson M, Dahlman-Wright K, Gustafsson JA, Williams CM.(PubMed)

General Health: Allergies - Latex allergy

Types of Allergy
Latex allergy
Latex allergy is defined as a condition of immune over reaction of an individualize after exposing to natural rubber latex, a product made from fluids of the rubber tree.

K.1.How to determine the severity of the allergic effects
Depending to the allergy stimulating effect, some researchers suggested to scale the severity from 1 to 4 and followed by degeneration scale, but from -1 to -4
K.1.1. The severity scale from +1 to +4
+1. The first level of stimulationIf there is no symptoms at all or If the patient is alert and function morally after exposing
+2. The second level of stimulationThe patient have become irritable, hyperactive, tense, thirsty, etc. after exposing
+3. The third level of stimulation
The patient have become hypomanic, aggressive, apprehensive, etc.
+4. The fourth level of stimulationThe patient have become mania, agitation, over excitement, etc.
K.1.2. Degeneration scale from -1 to -4
-1. If a patient is experience symptoms of reaction of runny nose, hive, diarrhea, etc.
-2. If a patient is experience symptoms of reaction of tiredness, fatigue, swelling etc.-3. If a patient is experience symptoms of reaction of depression, mental disturbance, confusion, mood change, etc.-4. If a patient is experience symptoms of reaction of sever depression, paranoia, etc.

K.2. Symptoms
Symptoms are the result in nasal congestion, due to Grass Pollen cause of a chain reaction that leads the mast cells in these tissues to release histamine, causing dilation of many small blood vessels in the nose and swelling to nasal pathway of which can affects the daily activity including quality of life, productivity, and other chronic conditions, including asthma. of which can affects the daily activity including quality of life, productivity, and other chronic conditions, including asthma. According to the study of "Latex allergy" by Gawchik SM. (Source from Crozer Chester Medical Center, President's House, Chester, PA 19013. drgawchik@yahoo.com). posted in PubMed, researchers indicated in abstract thatAllergy to natural rubber latex is an important clinical condition that occurred after the institution of universal precautions to protect healthcare workers. A rapid increase and production of both examination and surgical gloves resulted in an epidemic of allergy to latex protein. Healthcare workers in both the medical and dental environments, as well as specific groups of individuals including those with spina bifida, myelodysplasia, and food allergies (banana, kiwi, avocado, and others), were at increased risk of sensitization. Clinical symptoms in the latexallergic individual ranged from type I hypersensitivity reaction including rhinoconjunctivitis, asthma, and systemic reaction to type IV hypersensitivityreaction, which occur from the chemicals added during the manufacturing process.
and
1. Asthma-like symptoms
2. Itching
3. Sneezing
4. Wheezing
5. Sinus pain
6. Tearing eyes
7. Runny nose
8. Itchy eyes and throat
9. Etc.

K.3. Diagnosis
If you are experience Latex Allergy, it is possible to find what types of allergen have trigger that. After recording the family history and a complete physical exam. you doctor may order
1. Skin test
a. Intradermal test
It is one of most common test but time consuming( some patient may return for more 20 time for the injection) in diagnosis of allergy and depending to the symptoms, by injecting small amounts of diluted allergens into the top layers of the skin to see how the immune system react to them.
b. Skin prick testing
Similar to the Intradermal test, but the diagnosis involves in applying a drop of allergen into to punctures made on the skin.

2. Blood test (RadioAllergoSorbent Test)
This is the test for evaluating of the levels of IgE-mediated food allergies react to a particular allergen. If you RAST score is higher than the predictive value for that food, 95% chance you will have an allergic reaction. Unfortunately, non-IgE mediated allergies cannot be detected by this method.

3. Challenge Tests
Because of the risk of anaphylaxis, most doctors will avoid the test unless it is absolutely necessary and the test is performed only in the hospital. In this test, suspected allergen package into capsule taken by patient and signs or symptoms of an allergic reaction are observed.

4. Etc.

K.4. Prevention
There is no way to prevent them unless you can prevent yourself from contact them. But one can always enhance the immune system by eating healthy and living a healthy lifestyle. For more information of healthy foods, visit 100+ Healthy Foods Classification

K.5. Treatments
K.5.1. In conventional Medicine
According to the "Latex allergy" by Gawchik SM. (Source from Crozer Chester Medical Center, President's House, Chester, PA 19013. drgawchik@yahoo.com, Mt Sinai J Med 78:759-772, 2011. © 2011 Mount Sinai School of Medicine), researchers suggested that diagnosis of latex allergy is based on a clinical history that correlates the development of symptoms in relationship to exposure. In the United States there are no skin tests approved by the Food and Drug Administration. Therefore a combination of clinical judgment and serologic testing such as ImmunoCAP and Immulite is helpful. The primary treatment of latex allergyis avoidance of exposure to the latex protein.
1. There is no specific treatment for Hay fever, but depending to the symptoms. Medication includes bronchodilators, anti-allergics, antihistamines, NSAIDs, etc.
2. Allergic shot
Allergy shot, also known as immunotherapy, contains extracts from the most common substance which people are allergic to, including pollen, insects, pets, etc., by providing long-term relief from certain symptoms. In some people, after series of allergic shot, the disease is cured.

K.5.2. Herbs
1. Garlic
It is best known for treating cold and flu and enhances immune system against alll types of foreign invasion. According to the study of "Immunomodulatory Effects of Aged Garlic Extract" Eikai Kyo, Naoto Uda, Shigeo Kasuga and Yoichi Itakur, Posted in the "Journal of Nutrition" in March 2001, researchers strongly suggest that AGE (Aged Garlic Extract) could be a promising candidate as an immune modifier, which maintains the homeostasis of immune functions; further studies are warranted to determine when it is most beneficial.

2. Turmeric
Turmeric paste has been used in traditional herbal medicine as an antimicrobial and anti-inflammatory agent, it also helps to treat allergy. According to an article "Vitamin D and turmeric for allergies" by Joe Graedon and Teresa Graedon posted in Washington Post, May 11-2009, the authors wrote that In animal studies, turmeric prevents the release of histamine from mast cells (Molecular Nutrition and Food Research, September 2008). If it works similarly in humans, this would prevent allergy symptoms from developing.

3. Grape seed extract
Grape seed extract is best known for its antioxidant property in delay aging, it also acts as a natural histamine inhibitor, thus reducing the risk of allergic responses.

4. Licorice root
Beside is nest known to lower stomach acid levels, relieve heartburn and indigestion, licorice root is also boost the levels of interferon of immune system to fight off attacking viruses. According to the article of "Licorice, plantain and nettle herbs used in the treatment of Allergies" posted in Bitteroot restorationthe author wrote that This ( Licorice root) can actually help to counteract many of the symptoms that are associated with allergies.: It also contains substances which work to thin the mucus and soothe to respiratory passages, which can reduce irritation that often accompanies allergies and their symptoms.

5. Etc.

K.5.3. In traditional Chinese medicine
In a study of "Complementary and alternative medicine in pediatric allergic disorders." by Li XM. (Source from Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA., posted in PubMed, researcher indicated that in the last 2-3 years, there have been more controlled studies of TCM for allergic asthma and allergic rhinitis. Several publications including ours indicate that some TCM herbal formulas are well tolerated and produce some level of efficacy. Some herbal formulas also showed beneficial immunomodualtory effects. Several preclinical studies demonstrated that the food allergy herbal formula-2 was effective in protecting against peanut anaphylaxis in animal models. Two TCM products have entered clinical trials in the United States for treating asthma and food allergy, respectively. Both of these trials include children. In Summary, researcher concluded that Recent studies indicate that TCM therapy including herbal medicines and acupuncture for allergic disorders in children is well tolerated. There are also promising clinical and objective improvements. More controlled clinical studies are encouraged.

1. Xin Yi Hua is a lily-shaped flower with a hairy bud and Xin-yi-san (Magnolia Flower Powder)a. It is a type of traditional Chinese medicine used to treat allergy and dramatically reduces the symptoms of sneezing, anosmia, nasal congestion and profuse rhinorrhea (runny nose) caused by allergies triggered by dust mites, pets and fungi.According to the study of "Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects" bySien-Hung Yang, Chia-Li Yu, Ying-Lin Chen, Sheng-Lin Chiao, Mei-Ling Chen f. Posted in International Immunopharmacology 10 (2010) 951–958, researchers found that this proposal is based on the fact that different combinations of Chinese herbs involve different mechanisms. It appears that the immunosuppressive and anti-inflammatory effects derived from the mixed formula of Chinese herbs are broader than XYS. Nevertheless,we found that XYS alone sufficiently exerts immunomodulatory effects on patients with AR.In conclusion, this study provides evidence to support that XYS, when used singly, is beneficial in nasal allergic inflammation through enhancing IL-10 and IL-8 production.

b. Ingredient
Main use: Expels wind-cold, unblocks nasal passages, congestion, loss of smell, sinus headache.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

General Health: Anemia - The Association of Anemia and Cancer

The Best Weight Loss and Healthy Recipe - Just minutes to prepare Spring salad

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Best Weight Loss and Healthy Recipe - Just minutes to prepare Spring salad
Recipes attributed to Company Coming salad by Jean Pare

Takes just minutes to prepare this fruit, everyone enjoys
Lettuce cups 4 - 6
Orange sections, drained (or flesh) 10 Oz. 284 g
Banana sliced (see note) 2
Red grapes, halves. seeded 24
Whipping cream ( or 1 envelop topping) 1/4 cup, 50 mL
Salad dressing ( or mayonnaise) 1/4 cup 50 mL
Raisins 1/2 cup, 75 mL
Chopped walnuts or pecans ( optional)
Put lettuce on 4 to 6 plated
Arrange orange section, bananas and grapes on lettuce
Whip cream in small bowl until stiff. Fold salad dressing into whipped cream. Spoon over top of fruit.
Sprinkle with raisins and also with walnuts if you are using them. Serve 4 - 6.
Note: Dip banana in orange juice to keep from darkening.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Use of Orlistat 60 mg in the Management of Weight Loss Before Bariatric Surgery

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Orlistat 60 mg in the Management of Weight Loss Before Bariatric Surgery

In the study to evaluate the use of orlistat 60 mg taken up to 3 times daily as an adjunct to achieve the 10% preoperative weight loss recommended in this bariatric program prior to gastric bypass surgery, showed that Nineteen patients (5 males) and 19 age- and sex-matched controls were included. The mean (SD) initial body mass index for the treatment versus control group was, respectively, 49.5 (10.5) versus 47.2 (4.9) kg/m(2) (p = 0.559). At 3 months, the percent excess weight(EW) loss was 2.4 (3.8) (n = 15) versus 5.5 (7.6) (n = 19) (p = 0.111) and the percent total body weight (TBW) loss was 1.2 (1.9) versus 2.9 (4.1) (p = 0.103). At 6 months, the percent EW loss was 3.6 (6.4) (n = 9) versus 10.2 (8.0) (n = 16) (p = 0.036) and the percent TBW loss was 2.0 (3.4) versus 5.4 (4.2) (p = 0.048)(1).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1) "Use of Orlistat 60 mg in the Management of Weight Loss Before Bariatric Surgery (June)" by Malone M, Alger-Mayer SA, Lindstrom J.