Wednesday, July 6, 2016

Herbal therapy: Popular Herbal Licorice (Glycyrrhiza Glabra)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


     Herbal  Licorice (Glycyrrhiza Glabra)


Licorice (Glycyrrhiza Glabra) also known as sweetwood, is the genus Glycyrrhiza, belonging to the family Fabaceae, native to the Mediterranean and certain areas of Asia. The herb has been used in traditional medicine to treat treat skin diseases, coughs, constipation, bronchitis, inflammation, arthritis, etc.

Health Benefits
1. Anti cancers
In the investigation of the effects of a hexane/ethanol extract of G. uralensis (HEGU), which contains undetectable amounts of glycyrrhizin, on the apoptosis of androgen-insensitive DU145 cells found that HEGU induced apoptosis and increased the levels of cleaved caspase-9, caspase-7, caspase-3 and poly (ADP-ribose) polymerase (PARP). HEGU also induced mitochondrial membrane depolarization and cytochrome c release to the cytosol. HEGU increased the levels of Fas, death receptor 4 (DR4), cleaved caspase-8, Mcl-1S, and truncated Bid proteins. A caspase-8 inhibitor suppressed HEGU-induced apoptosis, according to "Isoangustone A present in hexane/ethanol extract of Glycyrrhizauralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway" by Seon MR, Lim SS, Choi HJ, Park SY, Cho HJ, Kim JK, Kim J, Kwon DY, Park JH.(1)

2. Prostate cancer
In the evaluation of the effects of a hexane-ethanol extract of Glycyrrhiza uralensis (HEGU), which lacks glycyrrhizin, on the metastatic characteristics of DU145 prostate cancer cells.
found that HEGU, which contains licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. The observed reductions in the activation of proteases and the levels of adhesion molecules may constitute a component of the mechanisms by which HEGU inhibits the migration and adhesion of prostate cancer cells, according to "Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells" by Park SY, Lim SS, Kim JK, Kang IJ, Kim JS, Lee C, Kim J, Park JH.(2)

3. Anti cardiotoxicity
In the exploration of the possibility of Glycyrrhiza uralensis licorice effect on DOX-induced cardiotoxicity found that the cells were pretreated with 0-15 mg/L HEGU, then treated with doxorubicin. The pretreatment of cells with HEGU resulted in a significant mitigation of DOX-induced reductions in cell numbers (34 +/- 7%) and increases in apoptosis (53 +/- 1%). The Western blot analysis of cell lysates showed that HEGU suppressed DOX-induced increases in the levels of p53, phospho-p53 (Ser 15), and Bax. In addition, HEGU induced an increase in the levels of Bcl-xL, regardless of DOX-treatment. HEGU inhibited the DOX-induced cleavage of caspases 9, 3, and 7, as well as DOX-induced poly(ADP-ribose) polymerase cleavage, according to "Hexane/ethanol extract of Glycyrrhizauralensis licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts" by Choi HJ, Seon MR, Lim SS, Kim JS, Chun HS, Park JH.(3)

47. Hirsutism and polycystic ovary syndrome treatments
In the investigation the effect of licorice on androgen metabolism in nine healthy women 22-26 years old, in the luteal phase of the cycle by giving 3.5 g of a commercial preparation of licorice (containing 7.6% W.W. of glycyrrhizic acid) daily for two cycles found that serum testosterone decreased from 27.8+/-8.2 to 19.0+/-9.4 in the first month and to 17.5+/-6.4 ng/dL in the second month of therapy (p<0.05). It returned to pre-treatment levels after discontinuation. Androstenedione, 17OH-progesterone, and LH levels did not change significantly during treatment. Plasma renin activity and aldosterone were depressed during therapy, while blood pressure and cortisol remained unchanged, according to "Licorice reduces serum testosterone in healthy women" by Armanini D, Mattarello MJ, Fiore C, Bonanni G, Scaroni C, Sartorato P, Palermo M(4)

5. Estrogenic activity
In the determination of glabridin and glabrene from licorice roots and its estrogenic effect on post-menopausal women, found that Glabrene activity was not inhibited by raloxifene. Therefore, glabridin shows greater similarity to estradiol-17beta and thus greater potential, with or without Vitamin D, to modulate bone disorders in post-menopausal women, according to "Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues" by Somjen D, Katzburg S, Vaya J, Kaye AM, Hendel D, Posner GH, Tamir S.(5)

6. Body fat mass
In the experiment of the effect of licorice in reducing body fat mass found thatlicorice was able to reduce body fat mass and to suppress aldosterone, without any change in BMI. Since the subjects were consuming the same amount of calories during the study, we suggest that licorice can reduce fat by inhibiting 11beta-hydroxysteroid dehydrogenase Type 1 at the level of fat cells, according to "Effect of licorice on the reduction of body fat mass in healthy subjects" byArmanini D, De Palo CB, Mattarello MJ, Spinella P, Zaccaria M, Ermolao A, Palermo M, Fiore C, Sartorato P, Francini-Pesenti F, Karbowiak I.(6)

7. Anti-inflammatory effects
In evaluation of the anti-inflammatory activity of licorice (LE) and roasted licorice(rLE) extracts
found that LE and rLE have benefits in protecting against both acute inflammation and chronic inflammatory conditions including rheumatoid arthritis. rLE may inhibit the acute inflammation more potently than LE, according to "Anti-inflammatory effects of licorice and roasted licorice extracts on TPA-induced acute inflammation and collagen-induced arthritis in mice" by Kim KR, Jeong CK, Park KK, Choi JH, Park JH, Lim SS, Chung WY.(7)

8. Osteoclastogenesis
In the assessment of the inhibitory effects of glabridin, a flavonoid purified fromlicorice root, on the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation and its molecular mechanisms in murine osteoclast progenitor RAW264.7 cells, found that that glabridin holds great promise for use in preventing osteoclastogenesis by inhibiting RANKL-induced activation of signaling molecules and subsequent transcription factors in osteoclast precursors and these findings may be useful for evaluating treatment options in bone-destructive diseases, according to "The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced osteoclastogenesis in RAW264.7 cells" by Kim HS, Suh KS, Sul D, Kim BJ, Lee SK, Jung WW(8)

9. Eosinophilic meningitis
In the determination of Diammonium glycyrrhizinate (DG), a compound related to glycyrrhizin (GL), a triterpene glycoside extracted from liquorice root and theirs effect on A. cantonensis, and compared these with therapy involving albendazole and dexamethasone found that The observations presented here suggest that the albendazole and dexamethasone combination could be replaced by the combination of albendazole and DG in treating eosinophilic meningitis, according to "The use of albendazole and diammonium glycyrrhizinate in the treatment of eosinophilic meningitis in mice infected with Angiostrongylus cantonensis" by Li Y, Tang JP, Chen DR, Fu CY, Wang P, Li Z, Wei W, Li H, Dong WQ.(9)

10. Caries
In the identification of functional foods and their components with the attemption of the use of synthetic chlorhexidine, and at the reduction or prevention of caries found that Some other foods able to act against MGS growth and/or their virulence factors in in vitro tests are: apple, red grape seeds, red wine (proanthocyanidins), nutmeg (macelignan), ajowan caraway (nafthalen-derivative), coffee (trigonelline, nicotinic and chlorogenic acids, melanoidins), barley coffee (melanoidins), chicory and mushroom (quinic acid). In vivo anticaries activity has been shown by cranberry (procyanidins), glycyrrhiza root (glycyrrhizol-A), myrtus ethanolic extract, garlic aqueous extract, cocoa extracts (procyanidins), and propolis (apigenin, tt-farnesol), according to "Food components with anticaries activity" by Gazzani G, Daglia M, Papetti A.(10)

11. Etc.

Side effects
1. The herb may interact with blood thin medicine such as warfarin
2. Do not use the herb if you have high blood pressure or heart diseases without approval from the related field specialist(a)
3. Do not use the herb in children or if you are pregnant
4. Licorice can lower potassium in the blood, if you are diagnosed with hypokalemia(a)
5. Do not use the herb, if you have untreated kidney diseases(a)
6. It may cause cognitive impairment(b)
7. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/8070427
(b) http://www.ncbi.nlm.nih.gov/pubmed/15869044

(1) http://www.ncbi.nlm.nih.gov/pubmed/20229524
(2) http://www.ncbi.nlm.nih.gov/pubmed/20487583
(3) http://www.ncbi.nlm.nih.gov/pubmed/18849542
(4) http://www.ncbi.nlm.nih.gov/pubmed/15579328
(5) http://www.ncbi.nlm.nih.gov/pubmed/15336701
(6) http://www.ncbi.nlm.nih.gov/pubmed/14594116
(7) http://www.ncbi.nlm.nih.gov/pubmed/20300198
(8) http://www.ncbi.nlm.nih.gov/pubmed/22038020
(9) http://www.ncbi.nlm.nih.gov/pubmed/22152396
(10) http://www.ncbi.nlm.nih.gov/pubmed/22030309

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Feng Wei Cao (Herba Pteridis Multifidae)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Feng Wei Cao (Herba Pteridis Multifidae)


Feng Wei Cao is also known as Pteris. The bland, slightly bitter and cold herb has been used in TCM as antibiotic, anti tumor and anti-hyperlipidemic and to treat infection, dysentery, diarrhea, vomiting blood, hepatitis, leukorrhea, tumors in intestine, lung and bladder, cancers of gynecology, etc., as it clears Heat, expels toxins, cools Blood, stops bleeding, etc., by enhancing the functions of large intestine, heart, liver, stomach and kidney channels.

Ingredients
1. Pterosin B,C,F,O,S
2. Pterosin C-3-O-β-D-glucoside
3. 2β,15α-dihydroxy-ent-kaur- 16-ene
4. 2β,16α-dihydroxy-ent-kaurane
5. Creticoside A, B
6. Apigenin-7-O-β-D-glucoside
7. Luteolin-7-O-β-D-glucoside
8. Tannin
9. Etc.

Health Benefits
1. Hypercholesteremic effects
In the investigation of the effect of G. paraguayense consumption on antioxidative status and serum lipid profiles in hypercholesterolemic subject, found that consumption of G. paraguayense may increase in vivo antioxidant activities and have some protective effects in decreasing oxidative stress in hypercholesterolemic subjects, according to “Effects of Graptopetalum paraguayense consumption on serum lipid profiles and antioxidative status in hypercholesteremic subjects’ byYu-Ling L, Hsin-Yi P, Hui-Min H, Ching-Hsiu L, Su-Tze C.(1).

 2. Hepatoprotective effects
In the evaluation of the water extracts of Graptopetalum paraguayense E. Walther (WGP) for 8 consecutive weeks in Sprague-Dawley rats, suggested that Graptopetalum paraguayense E. Walther exerts hepatoprotection via promoting antioxidative and anti-inflammatory properties against CCl(4)-induced oxidative liver damage, according to “Hepatoprotection of Graptopetalum paraguayense E. Walther on CCl₄-induced liver damage and inflammation” by Duh PD, Lin SL, Wu SC.(2).

3. Neuroprotective effects
In the evaluation of the neuroprotective potential of Graptopetalum paraguayense E. Walther leaf extracts on inflammation-mediated ischemic brain injury, found that the neuroactive effects of GEE were markedly associated with anti-oxidative potential, activation of serine/threonine and tyrosine phosphatases, and down-regulation of extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38, Akt, Src, Janus kinase-1, Tyk2, signal transducer and activator of transcription-1, and NF-kappaB and might be attributed to the presence of polyphenolic compounds such as gallic acid, genistin, daidzin, and quercetin, according to “Graptopetalum paraguayense E. Walther leaf extracts protect against brain injury in ischemic rats” by Kao TK, Ou YC, Raung SL, Chen WY, Yen YJ, Lai CY, Chou ST, Chen CJ.(3).

4. Antioxidant and antiproliferative activity
In the investigation of the antioxidant abilities of water (SGWE), 50% ethanolic (SGE50) and 95% ethanolic (SGE95) extracts from the stem of Graptopetalum paraguayense, and the extract with the highest antioxidant activity for its inhibitory effect on proliferation of human hepatoma (Hep G2) cell line, found that SGWE lowered cell viability, and induced G1 phase arrest and apoptosis in Hep G2 cells. These results demonstrated the antioxidant and anti-hepatoma potential of stem of Graptopetalum paraguayense, according to “In vitro antioxidant and antiproliferative activity of the stem extracts from Graptopetalum paraguayense” by Chen SJ, Chung JG, Chung YC, Chou ST.(4).

Etc.


Side Effects
1. Overdoses can be toxic
2. Do not use the herb in weak elder, or in case chronic diarrhea

3. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting with the related field specialist.
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21387322
(2) http://www.ncbi.nlm.nih.gov/pubmed/21195152
(3) http://www.ncbi.nlm.nih.gov/pubmed/20503468
(4) http://www.ncbi.nlm.nih.gov/pubmed/18457367




The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: TCM Herbal Medicine for Kidney Yin deficiency - Sheng Di Huang

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).


Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into          
                        

                   Kidney yin deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yin deficiency may also experience yin vacuity induced cold expressive syndrome, including soreness of waist and knees(1848), lassitude(1848) and fatigue(1848), short breath(1848), poor appetite(1848), aversion to cold(184), cold extremities(1848), ringing in the ears(1850), migraine(1849), hearing problems(1850), a dry mouth and throat(1851), pale fingernails(1851), tidal fever(1851)and night sweating(1851), soles(1851) and chest(1851), constipation(1852),,......... as the kidneys no longer perform their functions of regulating fluid in moistening and nourishing organs and tissues of the body. According to TCM, too much cold/raw foods can aggravate the condition.

In the review of the Data base provided by PubMed, kidney yin deficiency may induce functional impairment or metabolic derangements in vital organs/tissues(1853) persuaded a conglomeration of sundry chronic disease state(1853), cognitive dysfunction(1854), vasomotor symptoms(1855),..... leading to accumulation of fluid in the body organ, promoted accentuation of inflammatory development of phlegm.
Kidney yin deficiency has shown to alter amino acid metabolism(1856), energy metabolism(1856) and gut microflora(1856), anovulatory infertility(1857) and
hypertension(1858), hyperinsulinemia(1859) and hyperandrogenia(1859)..... of which related to symptoms of PCOs(1859).

         Herbal medicine for Kidney yin deficiency


1. Sheng Di Huang

(See kidney yang tonified herbal medicine)
[Shen di huang (The bitter, sweet, bitter and cold in nature)(1724) has been used in TCM as diuretic(1734), anti hyperglycemicagent(1726), anti cancers(1731)(1732) and to treat cough(1743), asthma(1744)(1746), lung inflammation induced shortness of breath(1745), and wheezing(1746), tinnitus(1747) and hearing loss(17447), poor memory(1741), bronchial contraction)1746), and chest tightness(1746), lower plasma glucose(1725)(1727), enhance heart function(1734)(1735) (small doses constrict the blood vessels and large doses dilate the blood vessel)(1724), and regulate steroid hormone(1736),..... by promoting the functions of heart, kidney, and liver channels(1724).



Chemical constituents(1724)
1. Leonuride
2. Aucubin
3. Catalpol
4. Melittoside
5. Melittoside
6. Rehmannioside A、B、C、D
7. 8-epiloganic acid 8
8. Ajugoside
9. Lysine
10. Histidine
11. Arginine
12. Sapartic acid
13. Glutamic acid)
14. Threonine
15. Serine
16. Gluycine
17. Alanine
18. Valine
19. Isoleucine
20. Leucine
21. Tyrosine
22. Phenylalnine
23. Etc.


Epidemiological studies proposed that rehmannia also displays anti metabolic syndrome(1728), including fatigue(1728), prediabetes(1728)(1737), LDL-C, hypertension(1729), lipid profile(1728)(1737), including total cholesterol (TC), triglyceride (TG), high and low density lipoprotein cholesterol (HDL-C, LDL-C)(1736)(1737), insulin resistance(1730), waist size(1736) and obesity(1742), through its effects in carbohydrate(1740)(1741) and lipid metabolism(1728) of which reduce risk of diabetes(1728)(1739) and cardiovascular disease(1728)(1736).
According to Kyung Hee University. formula Kyung-Ok-Ko, containing rehmannia, prevented and alleviated dehydroepiandrosterone-induced polycystic ovarian syndrome in rats model(1738).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(1246) [Clinical study of area of Jiangsu province of polycystic ovarian syndrome correlation distribution of traditional Chinese medicine syndrome type and improper diet]. [Article in Chinese] by Feng Y, Gao YP.(PubMed)
(1247) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan, J.(PubMed)
(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) by Liqin Zhao(1848) ontrolled trail on moxibustion for maintenance hemodialysis patients in deficiency syndrome]. [Article in Chinese] Li N1, Qiu MY, Hao JR, Zhang QM, Wang SH, Liang F, Yin Y, Luan J, Ge GZ, Qin T, Li BQ.(PubMed)
(1848) ontrolled trail on moxibustion for maintenance hemodialysis patients in deficiency syndrome]. [Article in Chinese] Li N1, Qiu MY, Hao JR, Zhang QM, Wang SH, Liang F, Yin Y, Luan J, Ge GZ, Qin T, Li BQ.(PubMed)
(1849) [Observation on therapeutic effect of the new Bianshi (stone needle) therapy on migraine]. [Article in Chinese] Yin ZJ1, Yan YJ, Bao HL(PubMed)
(1850) [Study on relation of kidney-deficiency with hearing damage and serum trace elements in patients with chronic nephropathy]. [Article in Chinese] by Yu J1, Xu Y, Fu XD.(PubMed)
(1851) [A family survey of syndromes of traditional Chinese medicine in patients with beta-thalassemia]. [Article in Chinese] by Wang WJ1, Wu ZK, Zhang XH, Liu WJ, Liu YM, Fang SP, Wang RX, Zhang C, Li PP, Luo RG.(PubMed)
(1852) The clinical experiences of Dr. CAI Gan in treating chronic constipation by Zhang ZL1, Zhu MP, Liu Q, Lei YX.(PubMed)
(1853) [Analysis of 35 cases of pathology in yin deficiency syndrome]. [Article in Chinese] by Dai HL, Chen ZL, Song QL.(PubMed)
(1854) Liuwei Dihuang decoction facilitates the induction of long-term potentiation (LTP) in senescence accelerated mouse/prone 8 (SAMP8) hippocampal slices by inhibiting voltage-dependent calcium channels (VDCCs) and promoting N-methyl-d-aspartate receptor (NMDA) receptors by Huang Y1, Zhang H, Yang S, Qiao H, Zhou W, Zhang Y.(PubMed)
(1855) Diagnosis of symptomatic postmenopausal women by traditional Chinese medicine practitioners by Zell B1, Hirata J, Marcus A, Ettinger B, Pressman A, Ettinger KM.(PubMed)
(1856) An integrated metabonomic and proteomic study on Kidney-Yin Deficiency Syndrome patients with diabetes mellitus in China by Jiang N1, Liu HF2, Li SD1, Zhou WX1, Zhang YX1, Zhang Q3, Yan XZ3.(PubMed)
(1857) [Preliminary study on relationship of disease-syndrome-symptom of ovulatory disorder infertility based on factor analysis]. [Article in Chinese] by Li M, Ma K, Shan J.(PubMed)
(1858) Traditional chinese medicine syndromes for essential hypertension: a literature analysis of 13,272 patients by Wang J1, Xiong X1, Liu W1.(PubMed)
(1859) [Clinical observation on treatment of hyperinsulinemia and hyperandrogenism anovulatory patient with replenishing kidney-yin drugs]. [Article in Chinese] by Zhou LR1, Yu J.(PubMed)

(1724) Di Huang(Complementary and Alternative Healing University)
(1725) Stachyose extract from Rehmannia glutinosa Libosch. to lower plasma glucose in normal and diabetic rats by oral administration by Zhang RX1, Jia ZP, Kong LY, Ma HP, Ren J, Li MX, Ge X.(PubMed)
(1726) Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism by Zhang R1, Zhou J, Jia Z, Zhang Y, Gu G.(PubMed)
(1727) Plasma glucose lowering mechanisms of catalpol, an active principle from roots of Rehmannia glutinosa, in streptozotocin-induced diabetic rats by Shieh JP1, Cheng KC, Chung HH, Kerh YF, Yeh CH, Cheng JT.(PubMed)
(1728) Evaluation of symptom, clinical chemistry and metabolomics profiles during Rehmannia six formula (R6) treatment: an integrated and personalized data analysis approach by van Wietmarschen HA1, van der Greef J, Schroën Y, Wang M.(PubMed)
(1729) The protective effect of Liu-Wei-Di-Huang-Fang in salt-sensitive hypertension rats byYang Q1, He Y, Wang W.(PubMed)
(1730) [Effect of Rehmannia glutinosa water extraction on insulin resistance and gene expression of resistin in type 2 diabetes mellitus rats]. [Article in Chinese] by Lv XF1, Meng QY, Guo XM.(PubMed)
(1731) Catalpol Inhibited the Proliferation of T24 Human Bladder Cancer Cells by Inducing Apoptosis Through the Blockade of Akt-Mediated Anti-apoptotic Signaling by Jin D1, Cao M, Mu X, Yang G, Xue W, Huang Y, Chen H.(PubMed)
(1732) Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells by Chao JC1, Chiang SW, Wang CC, Tsai YH, Wu MS.(PubMed)
(1733) Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats by Jang M1, Lee MJ1, Lee JM2, Bae CS3, Kim SH4, Ryu JH5, Cho IH6.(PubMed)
(1734) Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult byHuang C1, Cui Y, Ji L, Zhang W, Li R, Ma L, Xing W, Zhou H, Chen B, Yu J, Zhang H.(PubMed)
(1735) Saeng-Ji-Hwang has a protective effect on adriamycin-induced cytotoxicity in cardiac muscle cells by Chae HJ1, Kim HR, Kim DS, Woo ER, Cho YG, Chae SW.(PubMed)
(1736) [Effect of dandi tablet on blood lipids and sex hormones in women of postmenopausal stage]. [Article in Chinese] by Liang R1, Chen MR, Xu X.(PubMed)
(1737) Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice by Zhou J1, Xu G2, Yan J2, Li K2, Bai Z2, Cheng W2, Huang K3.(PubMed)


(1738) Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats by Jang M1, Lee MJ1, Lee JM2, Bae CS3, Kim SH4, Ryu JH5, Cho IH6.(PubMed)
(1739) Antidiabetic Effects of Carassius auratus Complex Formula in High Fat Diet Combined Streptozotocin-Induced Diabetic Mice by Wang ZH1, Hsu CC2, Lin HH3, Chen JH2.(PubMed)
(1740) Ameliorating effect and potential mechanism of Rehmannia glutinosa oligosaccharides on the impaired glucose metabolism in chronic stress rats fed with high-fat diet by Zhang R1, Zhou J2, Li M2, Ma H3, Qiu J2, Luo X4, Jia Z5.(PubMed)
(1741) d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol by Zhang XL1, An LJ, Bao YM, Wang JY, Jiang B.(PubMed)
(1742) Rehmannia inhibits adipocyte differentiation and adipogenesis by Jiang L1, Zhang NX, Mo W, Wan R, Ma CG, Li X, Gu YL, Yang XY, Tang QQ, Song HY.(PubMed)
(1743) The effect of a traditional Chinese prescription for a case of lung carcinoma by Kamei T1, Kumano H, Iwata K, Nariai Y, Matsumoto T.(PubMed)
(1744) The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma by Jung KH1, Choi HL2, Park S3, Lee G4, Kim M5, Min JK6, Min BI7, Bae H8.(PubMed)
(1745) [Shengdi injection on rat model of lung inflammation induced by lipopolysaccharides]. [Article in Chinese] by Liu L1, Tang L, Xu DS, Xia HL, Xie QM.(PubMed)
(1746) The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma by Jung KH1, Choi HL2, Park S3, Lee G4, Kim M5, Min JK6, Min BI7, Bae H8.(PubMed)
(1747) Rehmannia glutinosa activates intracellular antioxidant enzyme systems in mouse auditory cells by Yu HH1, Kim YH, Jung SY, Shin MK, Park RK, So HS, Kim KY, Lee DH, You YO.(PubMed)]

General Health: Anemia - The Effect of Anemia on Surgery

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                 Anemia 

Anemia is defined as a health condition in which our body do not have enough red blood cells or less than the normal quantity of hemoglobin in the blood to carry the function of delivery oxygen and nutrient to the tissue, including organs and cells. To read more about Anemia, click here


          The Effect of Anemia on Surgery


People with anemia are at risk during and after surgery due to not enough of red blood cells and sometime it can cause perioperative anemia as a result of losing too much blood, leading to insufficient hemoglobin to carry oxygen and nutrients for our body's organs and cells need.

1. Benefit of treating Anemia before surgery
If you are required surgery for whatever reasons, there are something you should consider to prevent complication during and after surgery.
Increase your red blood cells count or raise level of hemoglobin will reduce the need for blood transfusion during surgery, especial surgery that result in heavy blood loss.
1. Intake of foods with rich of folate, vitamin B12 and iron such as peas, lentil, soybeans and chickpeas, etc.
2. Vitamin C
Vitamin C is vital for the absorption of iron by increasing intake of vitamin C rich vegetables and fruits such as kiwi fruit, strawberries, and cantaloupes.
To increase to red blood cells, your doctor may prescribe
3. Vitamin pills
Folate, Vitamin B12, vitamin C and iron
4. Erythropoiesis-stimulating Agents
ESAs are given by injection or intravenously (through an IV) to stimulate the bone marrow to produce more red blood cells, thus raising the level of hemoglobin.
5. Contraceptive pill
Women who take the pill have reduced bleeding during period.
6. Etc.

It is important that you increase your red red blood cells well before the surgery to avoid the needs of blood transfusion, staying in hospital longer and decreasing the speed of healing of your incision and surgery.

Types of blood transfusion if necessary
You surgeon will suggest some of the best options for blood transfusion if necessary during surgery, please make sure you well understood and make your choice
1. Autologous transfusion
This may be a good choice, it is a blood transfusion that uses you own blood that has been previous stored, donated before the surgery, during an operation or post-operation.
2. Allogeneic transfusion
The type of blood transfusion with the use of donated blood
3. Collect and return
With the use of a special medical machine to collect your blood during or before surgery, then return them to your body following surgery.
4. Etc.

Blood loss minimization
Minimizing blood loss is always be considered for the best of the patient, especially for patience with anemia.
1. Lower blood pressure
Lower blood pressure helps to slower the blood flow, thus reducing the blood loss during surgery.
2. Position you body to reduce the blood flow, thus reducing the blood loss during surgery.
3. Using special medical instruments to minimize incision and control blood loss.
Etc.

  
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Best Weight Loss and Healthy Recipe - Old fashioned waldorf

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Best Weight Loss and Healthy Recipe - Old fashioned waldorf
Recipes attributed to Company Coming salad by Jean Pare

Just as good as way back then. Dressing is delicious
Diced peeled apple 1 cup, 250 mL
Chopped celery 1 cup, 250 mL
Halved and seeded red grapes 1/2 cup, 125 mL
Chopped walnuts 1/2 cup, 125 mL
Dressing whipping cream ( or 1 envelope topping) 1 cup, 250 mL
Granulated sugar 1/4 cup 60 mL
Vinegar 3 tbsp., 50 mL
Combine apples, celery, grade and nuts. Stir.
Whip cream until almost stiff. Add sugar. Beat in vinegar slowly. Pour over apple. Fold together. Serve 4.


Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of  Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss


In the study of Ninety participants were randomized to 3 groups (n = 30/group): high protein, high dairy (HPHD), adequate protein, medium dairy (APMD), and adequate protein, low dairy (APLD) differing in the quantity of total dietary protein and dairy food-source protein consumed: 30 and 15%, 15 and 7.5%, or 15 and <2% of energy, respectively. Body composition was measured by DXA at 0, 8, and 16 wk and MRI (n = 39) to assess visceral adipose tissue (VAT) volume at 0 and 16 wk. All groups lost body weight (P < 0.05) and fat (P < 0.01); however, fat lossduring wk 8-16 was greater in the HPHD group than in the APMD and APLD groups (P < 0.05) showed that The HPHD group gained lean tissue with a greater increase during 8-16 wk than the APMD group, which maintained lean mass and the APLD group, which lost lean mass (P < 0.05). The HPHD group also lost more VAT as assessed by MRI (P < 0.05) and trunk fat as assessed by DXA (P < 0.005) than the APLD group. The reduction in VAT in all groups was correlated with intakes of calcium (r = 0.40; P < 0.05) and protein (r = 0.32; P < 0.05). Therefore,diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain(1).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


(1)" Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women" by Josse AR, Atkinson SA, Tarnopolsky MA,Phillips SM.


Women Health: Menstrual Disorder - Dysmenorrhea - The Causes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                             Dysmenorrhea

Dysmenorrhea (painful menstruation) is defined as a condition of severe uterine pain during menstruation. Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen as resulting of over production of certain hormones in the prostaglandins family. In traditional Chinese medicine, dysmenorrhea is defined as a pain in the lower abdomen, appearing with menstrual cycle that can spread over to the whole abdomen and lumbosacral region, depending to diagnosis.

Types of dysmenorrhea
1. Primary dysmenorrhea
Primary dysmenorrhea is defined as no underlying cause for menstrual cramps or difficult menstruation occurring just before or during menstruation. It occurs about 90% in the girls in the first 2 years of menstruation. Some researchers suggested that it may be caused immature of the reproductive organs.

2. Secondary dysmenorrhea
Secondary dysmenorrhea is caused by gynecological diseases. including hormone imbalance, endometriosis, fibromas, pelvic immflammatory disease, etc.

                                       The Causes
A. Primary dysmenorrhea
1. Allergic reactions
Women eating food that causes the immune system to react over-aggressively and negatively due to a weakened immune system as well as resulting in an over-production of prostaglandins.

2. Nutritional deficiency
Deficiency of magnesium and DHEA encourages the excess prostaglandins that can facilitate onset of dysmenorrhea.

3. Unhealthy diet
Intake of high amounts of foods containing synthetic preservatives, color agents, additives, and caffeine causes tension in the nervous system, weakens the immune system, and increases inflammation of our body's system resulting in a distortion of hormone production.

4. Excessive estrogen
Balancing of estrogen and progesterone is necessary for a normal menstrual cycle. Women who are taking estrogen enhancing medications may cause an imbalance of estrogen and progesterone resulting in a hormone imbalance and menstrual cramps.

5. Over weight
Women who are overweight have twice the risk for having stronger and more persistent menstrual pain than women who are not.

6. Smoking.
Cigarettes are a stimulant that not only causes tension in our nervous system, but also distorts hormone production causing excessive production of prostaglandins. Women smokers are more likely to suffer from menstrual pain.

7. Stress
Stress is a psychological and physiological response to events that upset our personal balance in some way causing chemical imbalances in the brain resulting in irregular menstruation or menstrual cramps.

8. Etc.

B. Secondary dysmenorrhea (including those in primary dysmenorrhea)
1. Endometriosis
Endometriosis is a condition in which the cells that line the interior of the uterus dislodge and grows outside the uterine cavity resulting in no exit for the blood when estrogen levels drop causing dysmenorrhea.

2. Fibromas
These benign tumors form and grow in the uterus or the ovaries as a result of prolonged, dilatory menstruation or abortion as well as imbalances between estrogen and progesterone causing pain during the menstrual flow.

3. Pelvic inflammatory disease (PID)
PID is a bacterial infection of the uterus, fallopian tubes and ovaries.

4. Ectopic pregnancy
is defined as a condition in which the fertilized implant in somewhere else other than in the uterus. In most case, ectopic pregnancy occurs in the one of the Fallopian tube, causing tubal pregnancy. Ectopic pregnancy will end up in miscarriage cause of dysmenorrhea as the fertilized can not survive outside of uterus.

5. Sexual transmitting diseases
also known as sexually transmitted infection is an illness which can only transmit through sexual intercourse as a result from the infectious partner or IV drug needles after its use by an infected person, through childbirth or breastfeeding, including vaginal intercourse, oral sex, and anal sex. The disease can lead to infectious causes of dysmenorrhea.

6. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer