Medical Advisor Journals

Thursday, July 14, 2016

Phytochemicals in Foods - The Effects of Caffeic acid

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Caffeic acid

Caffeic acid is a organic phytochemical of the class of hydroxycinnamic acid, found in all plants, including burdock, hawthorn, artichoke, pear, basil, thyme, oregano, apple, etc.

Health Benefits
1. Liver cancer
In the studies of cancer chemoprevention with caffeic acid phenethyl ester (CAPE) in the resistant hepatocyte model of hepatocarcinogenesis, indicated that microsomal assays demonstrated that CAPE interfered with DEN activation diminishing nitrites similar to SKF525A and probably mediated by CYP2B1/2 inhibition. A single dose of CAPE before DEN treatment reduced the appearance of tumors by 43%, according to "Cancer Prevention Mediated by Caffeic Acid Phenethyl Ester Involves Cyp2b1/2 Modulation in Hepatocarcinogenesis" by Beltrán-Ramírez O, Macías Pérez R, Sierra-Santoyo A, Villa-Treviño S.(1)

2. Antioxidant Effect
In the testing the antioxidant properties of hydroalcoholic (HAB) and aqueous extracts (AB) from the bark and aqueous extract (AL) from the leaves of Stryphnodendron rotundifolium to determine a possible association between antioxidant activity and the popular use of this plant,
found that gallic acid, catechin, rutin and caffeic acid were the major components of the crude extracts of S. rotundifolium. Plant extracts inhibited Fe(II)-induced lipid peroxidation in brain homogenates. Iron chelation was also investigated and only HBA exhibited a weak activity. Taken together, the results suggest that S. rotundifolium could be considered an effective agent in the prevention of diseases associated with oxidative stress, according to "Antioxidant Effect of Stryphnodendron rotundifolium Martius Extracts from Cariri-Ceará State (Brazil): Potential Involvement in Its Therapeutic Use" by Costa JG, Leite Gde O, Dubois AF, Seeger RL, Boligon AA, Athayde ML, Campos AR, Rocha JB.(2)

3. Neurodegenerative effects
In the investigated Neuroprotective effect of CAPE in rat organotypic midbrain slice cultures and in vivo experimental mouse model of dopaminergic neurodegeneration by intranigral injection of lipopolysaccharide (LPS) and intrastriatal injection of 6-hydroxydopamine, found that neuroprotective effect of CAPE against LPS-induced injury was prevented by zinc protoporphyrin IX or anti-BDNF antibody. CAPE protected dopaminergic neurons and alleviated methamphetamine-induced rotational behavior also in 6-hydroxydopamine hemi-parkinsonian mice, according to "Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving heme oxygenase-1 and brain-derived neurotrophic factor" by Kurauchi Y, Hisatsune A, Isohama Y, Mishima S, Katsuki H.(3)

4. Immunoregulatory effects
In the study of PBMCs from asthmatic children (5.5 ± 3.3 years old, n=28) and healthy children (5.6 ± 2.8 years old, n=23) were co-cultured with CAPE in vitro with and without phorbol-12-myristate-13-acetate-ionomycin, found that he immunoregulatory effects of CAPE on human PBMCs may be through the induction of regulatory T cells, as evidenced by the enhanced transforming growth factor-beta 1 production from PBMCs from asthmatic children in our study, according to "The immunoregulatory effects of caffeic Acid phenethyl ester on the cytokine secretion of peripheral blood mononuclear cells from asthmatic children" by Sy LB, Yang LK, Chiu CJ, Wu WM.(4)

5. Antioxidant, anti-glycation and anti-inflammatory activities
In the investigation of 9 compounds isolated from the ethyl acetate soluble fraction of C. sinensis, namely protocatechuic acid (1), trans-caffeic acid (2), methyl rosmarinate (3), rosmarinic acid (4), kaempferide-3-O-β-D-glucopyranoside (5), kaempferol-3-O-β-D-glucopyranoside (6), quercetin-3-O-β-D-glucopyranoside (7), kaempferide-3-O-α-L-rhamnopyranosyl (1→6)-β-D-glucopyranoside (8) and kaempferol-3-O-α-L-rhamno-pyranosyl (1→6)-β-D-glucopyranoside (9) for biological activity and showed significant anti-inflammatory activity in the carrageen induced rat paw edema test and the antioxidant activities of isolated compounds 1-9 were evaluated by the DPPH radical scavenging test, and compounds 1, 2, 4 and 7-9 exhibited marked scavenging activity compared to the standard BHA. These compounds were further studied for their anti-glycation properties and some compounds showed significant anti-glycation inhibitory activity, according to "Antioxidant, anti-glycation and anti-inflammatory activities of phenolic constituents from Cordia sinensis" by Al-Musayeib N, Perveen S, Fatima I, Nasir M, Hussain A.(5)

6. Acute Chlamydia pneumoniae Infection
In the investigation of whether corn mint, a good source of natural phenols such as flavone glycosides and caffeic acid derivatives, extract would be beneficial against a universal respiratory tract pathogen, Chlamydia pneumoniae, infection, found that Linarin completely inhibited the growth at 100 μM. Inbred C57BL/6J mice were inoculated with C. pneumoniae K7. M. arvensis extract was given intraperitoneally once daily for 3 days prior to inoculation and continued for 10 days postinfection. The extract was able to diminish the inflammatory parameters related to C. pneumoniae infection and significantly (p = 0.019) lowered the number of C. pneumoniae genome equivalents detected by PCR at biologically relevant amounts, according to "Corn Mint ( Mentha arvensis ) Extract Diminishes Acute Chlamydia pneumoniae Infection in Vitro and in Vivo" by Salin O, Törmäkangas L, Leinonen M, Saario E, Hagström M, Ketola RA, Saikku P, Vuorela H, Vuorela PM.(6)

7. Male Fertility
In the assessment of the adverse effect of lambda cyhalothrin (LC) on reproductive organs and fertility in male rats and the protective role of caffeic acidphenethyl ester (CAPE), found that treatment with CAPE improved the reduction in the sperm characteristics, LC-induced oxidative damage of testes and the testicular histopathological alterations. Results indicate that LC exerts significant harmful effects on the male reproductive system and that CAPE reduced the deleterious effects of LC on male fertility, according to "Protective role of caffeic acid on lambda cyhalothrin-induced changes in sperm characteristics and testicular oxidative damage in rats" by Abdallah FB, Fetou H, Zribi N, Fakhfakh F, Keskes L.(7)

8. Anti-HIV Activity
In the sudy of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant DAPHNE ACUTILOBA Rehd. (Thymelaeceae), found that daphnenin ( 1) and caffeic acid N-octadecyl ester ( 13) showed definite anti-HIV activity with EC (50) values of 0.39 and 0.16 µg/mL, respectively, according to "Phenols with Anti-HIV Activity from Daphne acutiloba" by Huang SZ, Zhang XJ, Li XY, Jiang HZ, Ma QY, Wang PC, Liu YQ, Hu JM, Zheng YT, Zhou J, Zhao YX.(8)

9. Antihypertensive effect
In the investigation of the antihypertensive effect of Melothria maderaspatana leaf fractions on deoxycorticosterone acetate (DOCA)-salt-induced hypertensive rats and identification of compounds from the active fraction by GC-MS analysis, found that by GC-MS analysis, phytochemicals such as coumarin, vallinic acid, p-coumaric acid, gallic acid, caffeic acid, and ferulic acid were identified in EAFM. In conclusion, the EAFM controls blood pressure in DOCA-salt hypertensive rats and reverts the metabolic alterations in magnesium, copper and zinc., according to "Antihypertensive effect of Melothria maderaspatana leaf fractions on DOCA-salt-induced hypertensive rats and identification of compounds by GC-MS analysis" by Veeramani C, Al-Numair KS, Chandramohan G, Alsaif MA, Alhamdan AA, Pugalendi KV.(9)

10. Etc.

Chinese Food Therapy
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and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22291063
(2) http://www.ncbi.nlm.nih.gov/pubmed/22258340
(3) http://www.ncbi.nlm.nih.gov/pubmed/22224485
(4) http://www.ncbi.nlm.nih.gov/pubmed/22192260
(5) http://www.ncbi.nlm.nih.gov/pubmed/22158590
(6) http://www.ncbi.nlm.nih.gov/pubmed/22073967
(7) http://www.ncbi.nlm.nih.gov/pubmed/22025501
(8) http://www.ncbi.nlm.nih.gov/pubmed/21989641
(9) http://www.ncbi.nlm.nih.gov/pubmed/21964566

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Gou Teng or Jin Gou Teng (Ramulus cum uncis Uncariae)

Gou Teng or Jin Gou Teng (Ramulus cum uncis Uncariae)

Gou Teng is also known as Gamdir Vine. The sweet and cool herb has been used in TCM as sedative, anti platelet coagulation agent, etc. and to lower blood pressure, to release central nervous tension, treat epilepsy, rheumatoid arthritis, etc., as it calms convulsions, clears Heat, soothes the Liver, etc., by enhancing the functions of liver and pericardium channels.

Ingredients
1. Rhynchophylline
2. Isorhynchophylline
3. Isocorynoxeine
4. Corynantheine
5. Dihydrocorynantheine
6. Hirsutine
7. Hirsuteine
8. Corynoxeine
9. Isocorynoxeine
10. Hirsutine
11. Hirsuteine
12. Corynantheine
13. Etc.

Health Benefits
1. Tinnitus
In the investigation of the effect of TCM in treating tinnitus, different kinds of medicines were given to the patients of 2 groups with single blind trial. For the controls, only western medicines such as valium, nicotinic acid, mixture bromides, vitamin B Co, ATP and carbamazepine (if 100 mg of lidocaine added to 50% glucose solution intravenously was effective) were taken orally. For TCM-WM group patients, besides the drugs used above, herbal decoctions were given twice a day, and observed for 5 days per therapeutic course. The medicinal herbs consist of: Rhizoma Gastrodiae, Ramulus Uncariae cum Uncis, Poria cocos, Flos Chrysanthemi, Akebia quinata, Radix Polygoni Multiflori, Fructus Liquidambris, Radix Rehmanniae, Rhizoma Alismatis, Radix Scrophulariae, Fructus Lycii, Radix Glycyrrhizae, Semen Plantaginis and Semen Vaccariae, found that Of the therapeutic results in 32 cases of TCM-WM group, 11 cases (34.4%) showed absence of tinnitus, 16 (50%) improved, and 5 (15.6%) failed. The total effective rate was 84.4%. In 27 cases of the controls, 5 cases (18.6%) showed absence of tinnitus, 10 (37%) improved, and 12 (44.4%) failed. The total effective rate was 55.6%. It showed that the therapeutic results of TCM-WM group was better than those of the control, according to ” [Tinnitus treated with combined traditional Chinese medicine and Western medicine].[Article in Chinese]” by Yang DJ.(1).

2. Anti infection
In the investigation of a liquid and a powder made from a herbal complex consisting of Uncariae Ramulus cum Uncis, Agrimoniae Herba, Sanguisorbae Radix, Eclipta Prostrate Herba, Pulsatillae Radix, Sophorae Flavescentis Radix, Rehmanniae Radix and Glycyrrhizae Radix were studied for their anticoccidial activities in chickens, found that the birds medicated showed less bloody faeces than those without medication. The intestinal lesion was mild in the chicks medicated with herbal liquid without significantly different lesion score when compared with uninfected chicks, according to “Effects of a herbal complex against Eimeria tenella infection in chickens” by Du A, Hu S.(2).

3. Antioxidants
In the measurement the superoxide radical (O2) and hydroxyl radical (OH) scavenging activity from Mallotus repandus (Willd.) Muell.-Arg., Bauhinia championii Benth., Uncaria hirsuta Haviland and Uncaria rhynchophylla Miquel. O2- and OH, found that the scavenging potencies of water extracts of crude drugs were evaluated in terms of their ability to reduce the peaks of spin adducts. The extract of B. championii showed the greatest superoxide radical and hydroxyl radical scavenger activity, according to “Studies on Taiwan folk medicine, thang-kau-tin (II): Measurement of active oxygen scavenging activity using an ESR technique” by Lin JM, Lin CC, Chen MF, Ujiie T, Takada A(3).

4. Inflammatory effects
In the clarification of the effect of these crude drugs of “Thang-kau-tin” on Taiwan market: (1) the stem of Mallotus repandus (Willd.) Muell.-Arg, (2) the stem and root of M. repandus (Willd.) Muell.-Arg, (3) the stem of Bauhinia championii Benth, (4) the stem with hooks of Uncaria hirsuta Haviland and (5) as anti-inflammatory and liver-protective agents, found that the stem of M. repandus showed the best anti-inflammatory activity against the paw edema induced by carrageenan. Nevertheless, the acute increase of GOT and GPT levels caused by CCl4 were markedly decreased by the treatment of M. repandus (stem), B. championii and U. hirsuta as a recipe group. The pathological changes around the central vein including fatty change, ballooning degeneration, cell necrosis, the increase in lymphocytes and Kupffer cells were improved by the treatment with the group of crude drugs as mentioned above, according to “Studies on folk medicine “thang-kau-tin” from Taiwan. (I). The anti-inflammatory and liver-protective effect” by Lin CC, Lin JM, Chiu HF.(4).

5. Etc.

Side Effects
1. Overdoses may damage liver and heart
2. Do not use the herb in case of Qi deficiency
3. Do not use Gou Teng in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist.
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/2766421
(2) http://www.ncbi.nlm.nih.gov/pubmed/15228556
(3) http://www.ncbi.nlm.nih.gov/pubmed/7598091
(4) http://www.ncbi.nlm.nih.gov/pubmed/1605129

Most Common Diseases of 50plus: Thyroid disease: Thyroid adenoma – The Risk factors

Thyroid disease

Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.

Thyroid adenoma

Thyroid adenoma is a benign tumor started in the layer of cell lined the inner surface of the thyroid gland. The disease are relatively common among adults living in the United States. According to the study by the Mayo Clinic and Mayo Foundation, there is a report of 4 patients described in whom a follicular carcinoma developed following thyroidectomy for a benign follicular neoplasm. Most thyroid nodules are Thyroid adenoma.

The Risk factors

1. According to the study by the University of Campinas
a. Graves’ disease: the prevalence of thyroid nodules and thyroid carcinoma were 27.78% and 5.05%, respectively.
b. Older age (OR = 1.054; 95% CI = 1.029-1.080) and larger thyroid volumes (OR = 1.013; 95% CI = 1.003-1.022) increased the chance of nodules.
c. Younger age (OR = 1.073; 95% CI = 1.020-1.128) and larger thyroid volume (OR = 1.018; 95% CI = 1.005-1.030) predicted thyroid carcinoma.
d. Hashimoto’s thyroiditis: the prevalence of thyroid nodules and carcinomas were 50.7% and 7.8%, respectively. Nodules were predicted by thyroid volume (OR = 1.030; 95% CI = 1.001-1.062)(8).

2. Emotional stress and childbirth
98 patients with Graves’ disease have been compared to 95 patients with Hashimoto’s thyroiditis and to 97 patients with benign thyroid nodules (control group) in order to evaluate the triggering role of major stressors and pregnancy in the occurrence of autoimmune thyroid diseases. showed that Graves’ disease occurred after a pregnancy in 25% of the women in child bearing age versus 10% of the cases of Hashimoto’s (p 40 years and to explore the association between TN and its metabolic risk factors, found that the prevalence of TN was 46.6 % (39.7 %, men; 50.3 %, women) and it increased significantly with increasing age (P < 0.001). It was significantly higher in the group with hypertension than in that with normotension (P < 0.001) and was 43.0 % in the normal blood glucose group, 49.4 % in the prediabetes group, and 50.9 % in the diabetes group (P < 0.001). Logistic regression analysis indicated that hypertension [odds ratio (OR) = 1.121 (1.025-1.225)] as well as prediabetes and diabetes [OR = 1.130 (1.036-1.233)] were all independent risk factors for TN after adjustment for sex, age, body mass index, blood lipid levels, smoking status, and alcohol consumption(10).

4. Insulin resistance (IR)
According to the study by the Baskent University Faculty of Medicine, patients with impaired glucose metabolism have significantly increased thyroid volume and nodule prevalence(11). Other study indicated that MetS have significantly increased thyroid volume and nodule prevalence. Multivariate regression analysis model demonstrated that the presence of IR contributed substantially to this increased risk(12).

5. BRAF mutations and family history of thyroid disease
According to the study by the King Abdulaziz University, BRAF exon 15 was sequenced in 381 cases of thyroid lesions including Hashimoto´s thyroiditis, nodular goiters, hyperplastic nodules, follicular adenomas (FA), papillary TC (PTC), follicular variant PTC (FVPTC), microcarcinomas of PTC (micro PTC; tumor size ≤ 1 cm), follicular TC (FTC), and non-well differentiated TC (non-WDTC). Patients with PTC harboring no BRAF mutation (BRAFwt) were on average younger than those with a BRAF mutation (BRAFmut) in the PTC (36.6 years vs. 43.8 years). Older age (≥ 45 years) in patients with PTC was significantly associated with tumor size ≥ 4 cm (P = 0.018), vessel invasion (P = 0.004), and distant metastasis (P = 0.001). Lymph node (LN) involvement in PTC significantly correlated with tumor size (P = 0.044), and vessel invasion (P = 0.013). Of notice, taken the whole TC group, family history of thyroid disease positively correlated with capsular invasion (P = 0.025)(13).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(8) http://www.ncbi.nlm.nih.gov/pubmed/23762596
(9) http://www.ncbi.nlm.nih.gov/pubmed/9789594
(10) http://www.ncbi.nlm.nih.gov/pubmed/23720025
(11) http://www.ncbi.nlm.nih.gov/pubmed/23395200
(12) http://www.ncbi.nlm.nih.gov/pubmed/19633072
(13) http://www.ncbi.nlm.nih.gov/pubmed/22925390

The Best Weight Loss and Healthy Recipe - Fennel soup

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

The Obesity' Research and Studies of Obesity, disordered eating, and eating disorders

Women Health: Menstrual Disorder - Dysmenorrhea - Causes of Heat Pattern in TCM Perspective

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Dysmenorrhea

Dysmenorrhea (painful menstruation) is defined as a condition of severe uterine pain during menstruation. Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen as resulting of over production of certain hormones in the prostaglandins family. In traditional Chinese medicine, dysmenorrhea is defined as a pain in the lower abdomen, appearing with menstrual cycle that can spread over to the whole abdomen and lumbosacral region, depending to diagnosis.

Girls in South East Asia have learnt in their early women life from grand mother wisdom, that they do not engage in any activity that distorts their regular period. Menstruation disorders should be treated immediately, otherwise, it may cause wide range of women diseases, such as infertility, according to traditional Chinese medicine. In this article, we will discuss dysmenorrhea - causes of heat pattern in TCM perspective.

The Causes

1. Intake of spicy foods
Intake of spicy and hot foods may increase the body temperature that depletes the internal yin and causes liver's heat to rise and affects the normal function of nervous system in information transmitting between themselves and gland, leading stress, anxiety and emotional and physical stress.

3. Over drinking alcohol
Alcohol damages the liver that affects its ability in blood formation and storing, leading to liver blood stagnation in certain region in the productive organ, resulting in purple clots in the period.

4. Over exercises
Moderate exercise is helpful for blood circulation, over exercise diverts blood aways from the reproductive organ that cause not enough blood to support the normal function of the uterus in the yang phrase of menstrual cycle, leading to menstrual cramps and pains before, during and after menstruation

5. Kidney Yin deficiency
Kidney yin deficiency causes abnormal function of kidney in regulating the fluids the body tissues, leading to abnormal water retention in the body.

6. Infection or inflammation
Infection or inflammation caused by invasion of bacteria and virus due to weakening immune system in guarding our body from foreign substances, causing heat pattern in the body that affects the kidney yin, leading to its inability to support the normal function of uterus, thus increasing the risk of uterus contraction.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

General Health: Angina pectoris - Treatments In Traditional Chinese medicine perspective

C. In traditional Chinese medicine perspective
Traditional Chinese medicine defines angina as a diseases as a result of Ischemic heart disease (belongs to the categories of "xiong bi", "xin tong", "xin ji", "jue xin tong" and "zhen xin tong)either caused by Stagnation of Heart Blood of which leads to symptoms of localized stabbing chest pain aggravated at night, palpitation,restlessness, dark purple tongue, etc. in most cases or Heart Yin Deficiency of which lead to symptoms of chest pain and oppression, restlessness, insomnia, palpitation, night sweating, lumbago, weak waist and knees, dizziness, tinnitus. etc., in most cases
C.1. Formula(61)(62)
1. Jing Zhi Guan Xin Pian used for coronary heart disease, angina pectoris due tostagnation of heart blood
2. Ingredients
a. Radix Salviae Miltiorrhizae (Dan Shen)
b. Radix Rubra (Chi Shao)
c. Chuanxiong rhizome (Chuan Xion)
d. Flos Carthami. (Hong Hua)
e. Lignum Dalbergiae Odoriferae (Jiang Xiang0

C.2. Heart Yin Deficiency
1. Tian Wang Bu Xin Wan used for coronary heart disease, angina pectoris due toheart Yin Deficiency
2. Ingredients
a. Radix Salviae Miltiorrhizae (Dan Shen)
b. Rhizoma Acori Tatarinowii (Shi Chang Pu)
c. Radix Rehmanniae Glutinosae (Di Huang)
d. Radix Angelica Sinensis (Dang Gui)
e. Fructus Schisandrae Chinensis (Wu Wei Zi)
f. Tuber Ophiopogonis Japonici (Mai Men Dong)
g. Semen Ziziphi Spinosae (Suan Zao Ren)
h. Semen Biotae Orientalis (Semen Platycladi) (Bai Zi Ren)
i. Radix Codonopsis Pilosulae (Dang Shen)
j. Sclerotium Poriae Cocos (Fu Ling)
k. Radix Scrophulariae Ningpoensis (Xuan Shen)
l. Radix Polygalae Tenuifoliae (Yuan Zhi)
m. Radix Platycodi Grandiflori (Jie Geng)
n. Radix Glycyrrhizae Uralensis (Gan Cao)

Please consult with your doctor or related field specialist before applying.