Friday, August 12, 2016

Children Health: Attention Deficit Disorder (ADHD/ADD) - The Classification

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Attention Deficit Disorder (ADHD/ADD)

Attention Deficit Disorder (ADHD/ADD) also known as attention deficit hyperactivity disorder is a chronic disease occurs in certain age and years of a children, defined as a condition with characteristics of co-existence of attentional problems and hyperactivity. It effects about 5% of the all children in the world with boys have 3-4 times higher risk than girl. Over one third of children with ADHD will have continued symptoms existed into their adult life.


                       The Classification


ADHD is classified with coexistence of Disruptive behavior disorder
Although any disorder can be co-existed with ADHD, disruptive behavior disorder is one of most common one, including
1. Oppositional defiant disorder
Oppositional defiant disorder is defined as a behavior of defiance and disobedience to the authority.

2. Conduct disorder
Conduct disorder is defined as long-term (chronic) behavior problems, including Defiant or impulsive behavior such as aggression, destruction of property, stealing, etc.

3. Antisocial personality disorder
Antisocial personality disorder is defined as a characteristic of persistently disregard and violation of the rights of others, such as deceit, manipulation, etc.

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Regular Walking Reduces Risk and Progression of Impaired Fasting Glucose in 50 plus Adults

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Impaired fasting glucose is a condition of elevated glucose circulates in the blood plasma. According to definition, fasting blood sugar level from 100 to 125 mg/dL (5.6 to 6.9 mmol/L) is considered prediabetes.h
The joint study led by the Anton de Kom University of Suriname, suggested that the prevalence of diabetes in as risk factors among ethnic groups might be differences between these groups(1).

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk and progression of  Impaired Fasting Glucose in the younger and older elderly have been lacking, probably due to the effectiveness of modern diet restriction(2)(3) in syndrome controlling.

The Anhui Provincial Center for Disease Control and Prevention joint study in Primary Care and Community Settings in Anhui Province, China, showed the prominent of organized informal health promotion activities (eg, walking and tai chi groups) in improving systolic blood pressure, diastolic blood pressure, and both fasting and 2-hour post-prandial blood glucose(4).

In deed, active participants. in a randomly to control of one of five 13-week exercise programs such as walking, profoundly improved blood pressure, body composition, fasting lipids and glucose, and maximal aerobic power (VO2max)(5).

Dr. Walker KZ and colleagues at the Deakin University in support of regular walking inreduced risk of Impaired Fasting Glucose said, in a 12 weeks of walking study "walking increased the fitness of diabetic and normoglycemic women. Improvement of fasting blood glucose was related to the loss of centralized body fat rather than to improved fitness"(6).

In fact, Regular Walking is also found to reduce risk of Progression of Impaired Fasting Glucose to Early onset of  type 2 diabetes and  Diabetes Complications in older Adult. As we have mentioned in previous article provided below(7).

[ Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of health benefits of the younger elderly have not been explored.
According to Catholic University of Daegu, implementing a regular walking and exercise program in older adult reduce incidence of type II diabetes complications, through expressions of physical strength, and energy consumption (behavioral aspects), and decreased FBG, HbA1c, and TG levels (biochemical aspects(1).

In the review of Three databases, searched up to August 2014.of Eighteen studies involving 20 RCTs (866 participants) among type 2 diabetes patients, regular walking not only supported the decrease of HbA1c and BMI but also lowered the DBP among type 2 diabetes patients(2).

Dr. Fritz T and colleagues at the Center of Family Medicine, Karolinska Institutet said, "increase of regular physical activity equivalent to 45 min of walking 3 days/week may suffice to improve systolic and diastolic blood pressure, lipid metabolism and BMI "(3); improvement of plasma protein concentrations that promote blood hyperviscosity(4) and on cardiovascular risk factors and body composition in normoglycemic in patients with type 2 diabetes(5)

In fact, regular exercise not only reduces complications of types 2 diabetes in older adult(1)(2)(3) but
also prevents an early onset of the disease, due to its effect on reduced prevalence of hyperglycaemia and improved glycaemic control(9). According to Dr. Thyfault JP and Dr. Booth FW, physical inactivity (bed rest, increased sitting time, and reduced daily ambulatory activity), increases risk of metabolic dysfunctions in contribution to in the development of obesity and type 2 diabetes(6).

Physical inactivity, in sedentary behaviors, especially sitting may have a major impact on mortality, cardiovascular disease, type 2 diabetes, metabolic syndrome risk factors, and obesity as a result of inactivity initiated unique cellular processes involved metabolically unfit(7) of which may contribute to early onset diabetes.
Dr. Thyfault JP and Dr. Krogh-Madsen R.at the University of Missouri said, ' The transition from physical active to inactivity may result in insulin sensitivity, central adiposity and risk of chronic disease(8)].


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References
(1) Ethnic differences in prediabetes and diabetes in the Suriname Health Study by Krishnadath IS1, Nahar-van Venrooij LM1, Jaddoe VW2, Toelsie JR3.(PubMed)
(2) Low-glycaemic index diet to improve glycaemic control and cardiovascular disease in type 2diabetes: design and methods for a randomised, controlled, clinical trial by Chiavaroli L1, Mirrahimi A2, Ireland C1, Mitchell S1, Sahye-Pudaruth S1, Coveney J3, Olowoyeye O4, Maraj T4, Patel D1, de Souza RJ5,Augustin LS6, Bashyam B1, Blanco Mejia S1, Nishi SK1, Leiter LA7, Josse RG7, McKeown-Eyssen G8, Moody AR4, Berger AR9, Kendall CW10, Sievenpiper JL1, Jenkins DJ1.(PubMed)
(3) Comparison of control fasting plasma glucose of exercise-only versus exercise-diet among a pre-diabetic population: a meta-analysis by Zheng L1, Wu J2, Wang G3, Persuitte G4, Ma Y4, Zou L2, Zhang L2, Zhao M2, Wang J5, Lan Q1, Liu Z1, Fan H1, Li J2,6,7.(PubMed)
(4) Peer Support for Diabetes Management in Primary Care and Community Settings in Anhui Province, China by Zhong X1, Wang Z1, Fisher EB2, Tanasugarn C3.(PubMed)
(5) Exercise volume and intensity: a dose-response relationship with health benefits by Foulds HJ1, Bredin SS, Charlesworth SA, Ivey AC, Warburton DE.(PubMed)
(7) Regular Walking(4 Diseases Free to Age 100+) Reduces risk of Diabetes Complications in older Adult and Early onset of Diabetes by Kyle J. Norton

Phytochemicals in Foods- The Effects of Epigallocatechin

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                      Epigallocatechin


Epigallocatechin, including catechins, is phytochemicals of Flavan-3-ols, in the group of Flavonoids (polyphenols) with with the gallate residue being in an isomeric cis position, found abundantly in green tea, St John wort, black Tea, carob flour, Fuji apples, etc.

Health Benefits
1. Anti-Breast Cancer Activities
In the testing the hypothesis that administration of epigallocatechin-3-gallate (EGCG), a polyphenol present in abundance in widely consumed tea, and its inhibition of cell proliferation, invasion, and angiogenesis in breast cancer, found that treatment with combination of radiotherapy and EGCG feeding for 2-8 weeks to in vitro cultures of highly-metastatic human MDA-MB-231 breast cancer cells resulted in the following significant changes: (1) suppression of cell proliferation and invasion; (2) arrest of cell cycles at the G0/G1 phase; (3) reduction of activation of MMP9/MMP2, expressions of Bcl-2/Bax, c-Met receptor, NF-κB, and the phosphorylation of Akt. MDA-MB-231 cells exposed to 5-10 µM EGCG also showed significant augmentation of the apoptosis inducing effects of γ-radiation, concomitant with reduced NF-κB protein level and AKT phosphorylation, according to "Anti-Cancer Activities of Tea Epigallocatechin-3-Gallate in Breast Cancer Patients under Radiotherapy" by Zhang G, Wang Y, Zhang Y, Wan X, Li J, Liu K, Wang F, Liu Q, Yang C, Yu P, Huang Y, Wang S, Jiang P, Qu Z, Luan J, Duan H, Zhang L, Hou A, Jin S, Hsieh TC (1)

2. Anti cancers
In the review and outline the wide range of mechanisms by which epigallocatechingallate (ECGC) and other green and black tea polyphenols' inhibition of cancer cell found that EGCG reduced dihydrofolate reductase activity, which would affect nucleic acid and protein synthesis. It also acted as an aryl hydrocarbon receptor an-tagonist by directly binding the receptor's molecular chaperone, heat shock protein 90. In conclusion, green and black tea polyphenols act at numerous points regulating cancer cell growth, survival, and metastasis, including effects at the DNA, RNA, and protein levels, according to "Mechanisms of cancer prevention by green and black tea polyphenols" by Beltz LA, Bayer DK, Moss AL, Simet IM.(2)

3. Anti-atherosclerotic effects
In the localization and target sites of tea catechins underlying their biological activity including anti-atherosclerotic activity, found that ECg could suppress the gene expression of a scavenger receptor CD36, a key molecule for foam cell formation, in macrophage cells. These results, for the first time, showed the target site of a tea component ECg in the aorta and might provide a mechanism for the anti-atherosclerotic actions of the catechins, according to "(-)-Epicatechin gallateaccumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechins" by Kawai Y, Tanaka H, Murota K, Naito M, Terao J.(3)

4. Inflammatory effects
In the determination of the up-regulated expressions of IL-8 or PGE(2) in Streptococci or PAMP-stimulated HDPF were inhibited by catechins, (-)-epicatechin gallate (ECG) and (-)-epigallocatechin gallate (EGCG). In TLR2 ligand-stimulated HDPF, found that catechins might be useful therapeutically as an anti-inflammatory modulator of dental pulpal inflammation, according to "Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells" by Hirao K, Yumoto H, Nakanishi T, Mukai K, Takahashi K, Takegawa D, Matsuo T.(4)

5. Cardiovascular diseases
In the identification of green tea catechins and its lowering the risk of cardiovascular diseases, found that green tea catechins, particularly (-)-epigallocatechin gallate, interfere with the emulsification, digestion, and micellar solubilization of lipids, critical steps involved in the intestinal absorption of dietary fat, cholesterol, and other lipids. Based on the observations, it is likely that green tea or its catechins lower the absorption and tissue accumulation of other lipophilic organic compounds, according to "Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect" by Koo SI, Noh SK.(5)

6. Antiviral activities
In the observation of Catechin derivatives including (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and green tea extract (GTE) and theirs inhibition of the activities of cloned human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT), duck hepatitis B virus replication complexes reverse transcriptase (DHBV RCs RT), herpes simplex virus 1 DNA polymerase (HSV-1 DNAP) and cow thymus DNA polymerase alpha (CT DNAP alpha, found that GCG exerts a mixed inhibition with respect to external template inducer poly (rA).oligo (dT) 12-18 and a noncompetitive inhibition with respect to substrate dTTP for HIV-1 RT. Bovine serum albumin significantly reduced the inhibitory effects of catechin analogues and GTE on HIV-1 RT. In tissue culture GTE inhibited the cytopathic effect of coxsackie B3 virus, but did not inhibit the cytopathic effects of HSV-1, HSV-2, influenza A or influenza B viruses, according to "[The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases].[Article in Chinese]" by Tao P.(6)

7. Metabolic syndrome
In the investigation of Tea catechins, including the gallate esters of catechins, (-)-epicatechin gallate (ECG) and (-)-epigallocatechin gallate (EGCG). in reducing serum cholesterol concentrations and suppressing postprandial hypertriacylglycerolemia in experimental animals and humans, found that tea catechins and heat-treated tea catechins with the galloyl moiety improve lipid metabolism and contribute to the prevention of the metabolic syndrome, according to "Multifunctional effects of green tea catechins on prevention of the metabolic syndrome" by Ikeda I.(7)

8. Cognitive effects
in the examination of examined whether long-term administration of green tea catechins [Polyphenon E (PE): 63% of epigallocatechin-3-gallate, 11% of epicatechin, 6% of (-)-epigallocatechin and 6% of (-)-epicatechin-gallate] preventscognitive impairment in an animal model of AD, rats infused with Abeta1-40 into the cerebral ventricle, found that rats with preadministered PE had higher ferric-reducing antioxidation power of plasma as compared with the Vehicle group. Our results suggest that long-term administration of green tea catechins provides effective prophylactic benefits against Abeta-induced cognitive impairment by increasing antioxidative defenses, according to "Green tea catechins preventcognitive deficits caused by Abeta1-40 in rats" by Haque AM, Hashimoto M, Katakura M, Hara Y, Shido O.(8)

9. Cholesterol
In the examination of the influence of green tea extract, epicatechin (EC), epicatechin galate (ECG) as well as epigallocatechin galate (EGCG) on oxidative modifications of LDL of human blood serum, found that Catechins and green tea abilities to protect lipophilic antioxidant--alpha-tocopherol against oxidation have been also examined. The results reveal that peroxidation of LDL is markedly prevented by green tea extract and in a slightly weaker way by catechins (EGCG in particular), which is manifested by a decrease in concentration of conjugated dienes, lipid hydroperoxides, MDA, dityrosine and by an increase in tryptophan content, according to "The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro" by Ostrowska J, Skrzydlewska E.(9)

10. Anti diabetes
In the observation of the effect of tea catechins (epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicatechin gallate (ECG) and epicatechin (EC)) on markers of oxidative stress (malondialdehyde (MDA), reduced glutathione (GSH) and membrane -SH group) in erythrocytes from type 2 diabetics, found that tea catechins protect erythrocytes from t-BHP-induced oxidative stress, the effect being more pronounced in diabetic erythrocytes. The relative effectiveness of individual catechins are in the order of EGCG>ECG>EGC>EC. 7. We hypothesise that a higher intake of catechin-rich food by diabetic patients may provide some protection against the development of long-term complications of diabetes, according to "Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes" by Rizvi SI, Zaid MA, Anis R, Mishra N.(10)

11. Antioxidants
In the evaluation of the effects of the main polyphenolic components extracted from green tea leaves, i.e. (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG) and gallic acid (GA), against free radical initiated peroxidation of human low density lipoprotein (LDL), found that The antioxidative action of the green tea polyphenols includes trapping the initiating and/or propagating peroxyl radicals with the activity sequence EC>EGCG>ECG>EGC>GA for the AAPH initiated peroxidation, and reducing the alpha-tocopheroxyl radical to regenerate alpha-tocopherol with the activity sequence of ECG>EC>EGCG>EGC>GA and ECG>EGCG>GA>EC>EGC for the AAPH-initiated and BP-photosensitized peroxidations respectively, according to "Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized peroxidation of human low density lipoprotein" by Liu Z, Ma LP, Zhou B, Yang L, Liu ZL.(11)

12. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22280355
(2) http://www.ncbi.nlm.nih.gov/pubmed/17017850
(3) http://www.ncbi.nlm.nih.gov/pubmed/18657514
(4) http://www.ncbi.nlm.nih.gov/pubmed/20176036
(5) http://www.ncbi.nlm.nih.gov/pubmed/17296491
(6) http://www.ncbi.nlm.nih.gov/pubmed/1284389
(7) http://www.ncbi.nlm.nih.gov/pubmed?term=epicatechin%20gallate%20and%20fat%20oxidation
(8) http://www.ncbi.nlm.nih.gov/pubmed?term=epicatechin%20gallate%20and%20coginive%20effects
(9) http://www.ncbi.nlm.nih.gov/pubmed/17357329
(10) http://www.ncbi.nlm.nih.gov/pubmed/15730438
(11) http://www.ncbi.nlm.nih.gov/pubmed/10878235

Women Health: Premenstrual syndrome(PMS): Caused by Liver Qi stagnation in Chinese Herbs Perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                          Premenstrual syndrome(PMS)


Premenstrual syndrome is defined as faulty function of the ovaries related to the women's menstrual cycle, effected over 70% to 90% of women in the US and lesser for women in Southeast Asia because of difference in living style and social structure. The syndrome also interferes women's physical and emotional states, and daily activities as a result of hormone fluctuation and occurs one to two weeks before menstruation and then declines when the period starts.

Caused by Liver Qi stagnation in Chinese Herbs Perspective

Traditional Chinese medicine used over 4000 thousand years in treating women reproductive system disorder believed Pre menstrual syndrome is also caused by Liver Qi Stagnation in many cases.

Liver is important in carbohydrate synthesis and fat and protein metabolism(1). Liver qi stagnation causes abnormal function of liver in regulating the production of estrogen(2) and other hormones by glands(2) for controlling menstrual blood(3), leading to blood stagnation in the productive system and inducing symptoms of premenstrual syndrome including irritability, anger, depression(4)(5), etc,.

1. Angelica synthesis (Dang Qui)
Angelica synthesis, a queen herb for women reproductive tonic, has been used in traditional Chinese medicine in treating all women productive disorder(6) by releasing the qi stagnation cause of blood stasis(7) including pre menstrual syndrome. probably through its phytochemicals estrogenic(8)(9) and antiestrogenic(10) activities in restored hormone imbalance before ovulation and inhibited the over active uterus muscles(11)(12)(13) cause of pre menstrual pain and cramps(14)(15) and irregular menstruation(15).

2. Milk thistle seed
Milk thistle seed used in the traditional Western medicine over thousand year for liver tonic, showed to restore the liver qi stagnation caused by environment toxins and other toxins(16) and regenerate the liver's cells(16) in reduced symptoms of PMS(17) caused by the changes in monoamine neurotransmitters(17)

3. Peony (Shao Yao)
White peony showed to sooth liver qi stagnation(18) through a blood purifier and induced blood flow by increasing the liver in blood formation(19) and nourishing menstruation(20), relaxing spasm(22), relieving pain(22) and liver dysfunction(20) causes of tension of nervous system, such as anxiety(23)

4. Fennel seed (Xiao Hu Xiang)
Fennel seed released the stagnation caused by imbalance of yin yang qi in the liver(24) causes of reduced blood flow in inhibition symptoms of pain and cramps(25).

5. Yellow dock root
Yellow dock root, a liver tonic medicine(26), detoxifies liver by removing oxidative damage accumulated in the liver(27) induced liver dysfunction in regulating the production of hormones(2) before and after ovulation. 

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References
(1) Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle. Elmadhun NY1, Lassaletta AD, Chu LM, Bianchi C, Sellke FW.(PubMed)
(2) http://en.wikipedia.org/wiki/Estrogen
(3) http://www.ncbi.nlm.nih.gov/pubmed/23822457
(4) http://www.ncbi.nlm.nih.gov/pubmed/25211539
(5) http://www.ncbi.nlm.nih.gov/pubmed/20450050
(6) Dang Gui (Chinese Angelica Root) - Chinese Herbal Medicine
(7) http://www.ncbi.nlm.nih.gov/pubmed/21315572
(8)Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease by Choi RC1, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TT, Tsim KW.(PubMed)
(9) Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death by Zhu JT1, Choi RC, Chu GK, Cheung AW, Gao QT, Li J, Jiang ZY, Dong TT, Tsim KW.(PubMed)
(10) Isoflavones: chemistry, analysis, functions and effects on health and cancer by Ko KP.(PubMed)
(11) http://www.ncbi.nlm.nih.gov/pubmed/20195064
(12) http://www.ncbi.nlm.nih.gov/pubmed/12802720
(13) http://www.ncbi.nlm.nih.gov/pubmed/16573009
(14) http://www.ncbi.nlm.nih.gov/pubmed/23729340
(15) http://www.ncbi.nlm.nih.gov/pubmed/23883364
(16) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(17) http://www.ncbi.nlm.nih.gov/pubmed/22883410
(18) http://www.ncbi.nlm.nih.gov/pubmed/22779188
(19) Hemopoietic effect of extracts from constituent herbal medicines of Samul-tang on phenylhydrazine-induced hemolytic anemia in rats by Lee HW1, Kim H1, Ryuk JA1, Kil KJ2, Ko BS1.(PubMed)
(20) Characterization of the anti-influenza activity of the Chinese herbal plantPaeonia lactiflora by Ho JY1, Chang HW2, Lin CF3, Liu CJ4, Hsieh CF5, Horng JT6(PubMed)
(21) Anti-viral activity of water extract of Paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines by Lin TJ1, Wang KC, Lin CC, Chiang LC, Chang JS.(PubMed)
(23) Anxiolytic-like effect of paeonol in mice by Mi XJ1, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL.(PubMed)
(24) http://www.ncbi.nlm.nih.gov/pubmed/25211539
(25) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+seed+and+pain
(26) http://www.ncbi.nlm.nih.gov/pubmed/23766852
(27) http://www.ncbi.nlm.nih.gov/pubmed/17517459



Men Health: Prostate cancer: The effects of Vitamin B6

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                           Prostate cancer

The widespread of prostate cancer, once considered a disease of aging male, now have become major concerns of governments and scientific community in South East Asian with tendency to effect even younger age population. Suggestions emerged of over consuming bad fats in any time in history accompanied with unhealthy diet and life style may be the possible causes of the disease, linking to the economic prosperity over 2 decades. Foods for diseases' management have been prescribed in folk medicine over thousands of year as one of best medicine of nature in preventing and treating diseases, including prostate cancer.
Prostate cancer is defined as a condition in which the cells of prostate has become cancerous, causing abnormal cell growth with possibility of spreading to the distant parts of the body. Most prostate cancers are slow growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.


             The effects of Vitamin B6


Vitamin B6, also known as pyridoxine, is a water soluble vitamin found abundantly in green peas, yams, broccoli, asparagus and turnip greens,Peanuts, sunflower seeds, cashews and hazelnuts, meat, fish etc., with functions of amino acid, carbohydrate metabolism, brain health, and liver detoxification, etc.

Prostate cancer, a second leading cause of cancer death in men is defined as a condition in which the cells of prostate has become cancerous, causing abnormal cell growth with possibility of spreading to the distant parts of the body.
.
Epidemiological studies, focusing pyridoxine in reduced risk and treatment of prostate cancer have been inconclusive. Study of the link between intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans, showed no evidence for associations between B vitamins (folate, B12, and B6) and PC risk(1) and In the one-carbon metabolism and prostate cancerrisk, researcher found no convincing evidence for a protective role of one-carbon metabolism against prostate cancer(2). Dietary methyl groups(methionine, one-carbon units and choline (or the choline metabolite betaine) showed a a protective effect on the development of higher grades of prostate cancer in the "Hi-myc" mouse model of prostate cancer(3). Other suggestion indicated that high vitaminB-6 intake may improve prostate cancer survival among men with a diagnosis of localized-stage disease(4). A case-control study of diet and prostate cancer, included 328 men diagnosed with prostate cancer before the age of 75 years and 328 age-matched population controls, vitamin B6 was associated to reduced risk of prostate cancer(5)

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References
(1) Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 andProstate Cancer Risk in American Veterans by Vidal AC, Grant DJ, Williams CD, Masko E, Allott EH, Shuler K, McPhail M, Gaines A, Calloway E, Gerber L, Chi JT, Freedland SJ, Hoyo C.(PubMed)
(2) Dietary factors of one-carbon metabolism and prostate cancer risk by Weinstein SJ, Stolzenberg-Solomon R, Pietinen P, Taylor PR, Virtamo J, Albanes D.(PubMed)
(3) Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence by Shabbeer S, Williams SA, Simons BW, Herman JG, Carducci MA.(PubMed)
(4) One-carbon metabolism-related nutrients and prostate cancer survival by Kasperzyk JL, Fall K, Mucci LA, Håkansson N, Wolk A, Johansson JE, Andersson SO, Andrén O.(PubMed)
(50) A case-control study of diet and prostate cancer by Key TJ, Silcocks PB, Davey GK, Appleby PN,



Overcome Infertility: Syndrome Causes of Infertility

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                    Overcome Infertility 

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

                   Syndrome Causes of Infertility


Syndrome is defined as the aggregate of symptoms and signs associated with series of operations, events, or steps which lead to disease due to unhealthy or unwholesome process.
1. Anticardiolipin antibody syndrome
Antiphospholipid antibody syndrome is a disorder of coagulation, which causes blood clots. Women with high levels of anticardiolipin antibodies has a high risk of miscarriage. There are several types of such antibodies but the Ig G type is the one that correlates the most with pregnancy loss. It is said that intakes of low dose of aspirin or blood thinner will help to avert the problem. Make sure you check your antibody every eight weeks to prevent early miscarry.

2. Rokitansky syndrome
An inherit of birth defect with a malformation of vagina and absence of uterus.
3. Polycystic ovary syndrome (PCOS)
PCOS is a condition associated with the irregular ovulation leading to excessive building up the uterine lining and increasing the risk of infertility. Women with PCOS are found to have high levels of testosterone and high circulation of levels of insulin.

4. Klinefelter's syndrome
Genetic defect of male with one chromosome Y and 2 chromosome X leading to hormone imbalance including lack of testosterone. male breast, small testes and interfere with normal sperm production (semen found to have no sperm) causing infertility.

5. Kallmann's syndrome
A malfunction of hypothalamus gland at birth that interferes with production of gonadotropin-releasing hormone causing delay of puberty.
a) In men, it causes low levels of testosterone resulting of small size ****, cryptorchism leading to infertility because of no sperm during ejaculation.
b) In women, it causes no menstrual period and no egg production.

6. Cushing's syndrome
Cushing's syndrome is a chronic illness caused by over production of cortisol hormone leading to lower sperm production in male and abnormal ovulation in women.

7. Asherman's syndrome
Asherman's syndrome is a condition characterized by the presence of scars within the uterine cavity. It is caused by scars after a D&C is performed on a recently pregnant uterus including a missed or incomplete miscarriage, birth, or elective termination in removing retained products of conception and placental remains causing endometrium inability to response to the estrogen during menstrual cycle leading to infertility.


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The Best Weight Loss and Healthy recipe: Choco-Nana Smoothie

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Recipe by eat well and lose weight by better Holmesd and Gardens (more than 500 delicious sastifying recipes), published by Houghton Miffin Harcourt www.hmhbooks.com

In a blender combine 1 small banana, one 6-ounces carton vanilla fat-free yogurt, 1/2 cup of fat free milk, 2 tablespoons chocolate syrup, and 1/2 teaspoon vanilla. If desired, add ice.
Cover and blend.
Serve with half of whole grain English muffin spread with 1 tablespoon peanut butter.

Per serving: 454 cal., 10g fat(2g sat. fat). 6mg chol., 409 mg sodium, 78g carb., 52 g sugar, 6g fiber, 19g pro.



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