Medical Advisor Journals

Friday, August 19, 2016

Herbal therapy: Popular Herbal Shepherd's purse (Capsella bursa-pastoris)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Shepherd's purse (Capsella bursa-pastoris)

Sheperd's purse is a common weed, in the genus Capsella, belonging to the family Brassicaceae, native to Eastern Europe and the western two thirds of the Asian part of Turkey. The herb has been used in traditional medicine to treat Rheumatic joints, ecchymosis, bruises, strained parts, stomach troubles, such as diarrhea, dysentery, gastritis, gall bladder, kidney and bladder trouble, liver colics, disturbed metabolism, venereal disease, lung tuberculosis, bleeding lungs, etc.

Health Benefits
1. Antitumor and anti-intoxication activities
Fumaric acid, isolated as the active component of Capsella bursa-pastoris herb was found to reduce markedly the growth and viability of Ehrlich, MH134, and L1210 mouse tumor cells in culture at concentration of 0.3 approximately 1.2 mg/ml and exhibited activity to enhance the recovery of the cells from the toxic effects of mitomycin C, aflatoxin B1, N-methyl-N'-nitro-N-nitrosoguanidine, and potassium 1-methyl-7-[2-(5-nitro-2-furyl) vinyl]-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate, according to "Antitumor and anti-intoxication activities of fumaric acid in cultured cells" by Kuroda K, Akao M.(1)

2. Antimicrobial effects
In the investigation of 11 weeds collected from the Menoufeya district for phytochemical compounds effective against several representatives of bacteria and yeasts, found that that Soxhlet benzene extracts, especially those of Capsella bursa-pastoris (L.) Medik., were the most effective. Alkaloids and flavonoids ofCapsella gave the highest antibiotic potencies and had the broadest antimicrobial spectra, according to "Preliminary screening of some Egyptian weeds for antimicrobial activity' by El-Abyad MS, Morsi NM, Zaki DA, Shaaban MT.(2)

3. Uterotonic effect
In evaluation of Water extracts (infusions) from a group of medicinal plants in terms of their activity enhancing the uterine tonus in a series of experiments with a preparation of an isolated rabbit and guinea pig uterine horn, found that the combined preparation 'Antiinflamin', consisting of a pooled freeze-dried extract from three plants and chemotherapeutic agents produced a good enhancing effect, in the form of 'comprets' for intrauterine application at the rate of one compret per 2500 cm3, according to "[Uterotonic action of extracts from a group of medicinal plants].[Article in Bulgarian]" by Shipochliev T.(3)

4. Anti- Ehrlich solid tumor
in the determination of the treatment of ICR mice with i.p. injections (0.14 g/kg/day) of the extract of Capsella bursa-pastoris herb in solid growth of Ehrlich tumor cells,found that the acidic substance was identified as fumaric acid and was effective in inhibiting the growth of Ehrlich solid tumor at a dose of 10 mg/kg/day. The 50% lethal dose (i.p.) of this acid was 266 mg/kg, according to "Inhibitory effect ofCapsella bursa-pastoris extract on growth of Ehrlich solid tumor in mice" by Kuroda K, Akao M, Kanisawa M, Miyaki K.(4)

5. Infertility?Capsella bursa-pastoris ('Shepherd's Purse'), dried and ground, was added at rates of 20 and 40% to the stock diet of male and female mice, found thatat the 40% level, both materials impeded ovulation and produced temporary infertility in males and females. 20% Capsella did not affect female fertility, and previous experiments had shown that an equivalent amount of grass meal was harmless, according to 'THE EFFECT OF CERTAIN PLANT PREPARATIONS ON THE FERTILITY OF LABORATORY MAMMAL" by JUNE EAST(5)

6. Multiple sclerosis
In the evaluation of Fumarates (found abundantly in Shepherd's purse) and its improvemant of multiple sclerosis (MS) and psoriasis, found that In mice,fumarates also generate type II DCs that induce IL-4-producing Th2 cells in vitro and in vivo and protect mice from experimental autoimmune encephalomyelitis. Type II DCs result from fumarate-induced glutathione (GSH) depletion, followed by increased hemoxygenase-1 (HO-1) expression and impaired STAT1 phosphorylation. Induced HO-1 is cleaved, whereupon the N-terminal fragment of HO-1 translocates into the nucleus and interacts with AP-1 and NF-κB sites of the IL-23p19 promoter, according to"Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells" by Ghoreschi K, Brück J, Kellerer C, Deng C, Peng H, Rothfuss O, Hussain RZ, Gocke AR, Respa A, Glocova I, Valtcheva N, Alexander E, Feil S, Feil R, Schulze-Osthoff K, Rupec RA, Lovett-Racke AE, Dringen R, Racke MK, Röcken M.(6)

7. Etc.

Side effects
1. Overdose can cause gastrointestinal discomfort such as stomach upset.
2. Shepherd's purse may cause allergic effects such as skin redness and swelling
3. Do not use the herb in new born or children, or if you are pregnant or breast feeding with out approval from the related field specialist.
4. If you are taking high blood pressure, thyroid gland, or heart related medication, please consult with your doctor before taking the herb.
5. Shepherd`s purse may interact with other medication including coagulation medicine
6. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/7327376
(2) http://www.ncbi.nlm.nih.gov/pubmed/2336037
(3) http://www.ncbi.nlm.nih.gov/pubmed/7314446
(4) http://www.ncbi.nlm.nih.gov/pubmed/1268843
(5) http://joe.endocrinology-journals.org/content/12/4/267.abstract
(6) http://www.ncbi.nlm.nih.gov/pubmed/21987655

General Health: Cirrhosis Prevention - The Phytochemicals

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cirrhosis

Cirrhosis is defined as a condition of irreversible scarring liver as a result of liver tissue by fibrosis due to final phase of chronic liver diseases of that can lead to poor function of the liver and liver failure. According to the statistics, Number of discharges with chronic liver disease or cirrhosis as the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population: 10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in South-East Asia.

The Prevention

The Phytochemicals to prevent Cirrhosis
1. Emodin
Emodin is a orange crystalline compound, C14H4O2(OH)3CH3 found in rhubarb and other plants.
In the study to investigate the role of emodin in protecting the liver against fibrogenesis caused by carbon tetrachloride (CCl(4)) in rats and to further explore the underlying mechanisms, showed that
Emodin protects the rat liver from CCl(4)-induced fibrogenesis by inhibiting HSC activation. Emodin might be a therapeutic antifibrotic agent for the treatment of hepatic fibrosis(58).

2. Hesperetin
Hesperetin is flavonoids derived from Citrus fruits. In the study to evaluate the hepatoprotective effect of hesperetin (HTN) on cadmium (Cd) induced hepatotoxicity in male Wistar rats, showed that HTN at a dose of 40 mg/kg body weight/day exhibits significant (p<0.05) hepatoprotection compared with other two doses (10 and 20 mg/kg body weight/day). The histopathological studies in theliver of rats also supported that HTN (40 mg/kg) markedly reduced the toxicity of Cd and preserved the histoarchitecture of the liver tissue to near normal(59).

3. Silibinin
Silibinin (SB) is a major flavonolignan compound of silimarin and is found in milk thistle of Silybum marianum. In the study to delineate the ameliorative role of silibinin against arsenic-induced hepatotoxicity in rats. Rats were orally treated with arsenic alone (5 mg/kg body weight (bw)/day) plus silibinin (75 mg/kg bw/day) for 4weeks, showed that administration of silibinin exhibited a significant reversal of arsenic-induced toxicity in hepatic tissue. All these changes were supported by reduction of DNA damage in hepatocytes and histopathological observations of the liver(60).

4. Diallyl tetrasulfide (DTS)
diallyl tetrasulfide (DTS) is a natural compound found abundantly in fresh and aged garlic. According to the study by Annamalai University, administration of DTS at 40 mg/kg body weight significantly normalised the activities of hepatic marker enzymes, compared to other doses of DTS (10 and 20 mg/kg body weight). In addition, DTS (40 mg/kg body weight) significantly reduced the accumulation of Cd and the level of lipid peroxidation, and restored the level of antioxidant defense in the liver. Histological studies also showed that administration of DTS to Cd-treated rats resulted in a marked improvement of hepatocytes morphology with mild portal inflammation(61).

5. Phyto-power dietary supplement
Curcumin has been extensively studied for its therapeutic effects in a variety of disorders. Fermented soy consumption is associated with a low incidence rate of chronic diseases in many Asian countries. According to the study by the Chang Jung Christian University, phyto-power dietary supplement (50 or 100 mg kg(-1)) was administered by oral gavage daily for four weeks. Liver morphology, function, and fibrotic status were examined in DMN induced hepatic fibrogenesis. However, a phyto-power dietary supplement alleviated liver damage as indicated by histopathological examination of the α-smooth muscle actin (α-SMA) and collagen I, accompanied by the concomitant reduction of transforming growth factor-β1 (TGF-β1) and matrix metalloproteinase 2 (MMP2)(62).

6. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.cdc.gov/nchs/fastats/liverdis.htm
(58) http://www.ncbi.nlm.nih.gov/pubmed/19824107
(59) http://www.ncbi.nlm.nih.gov/pubmed/21134734
(60) http://www.ncbi.nlm.nih.gov/pubmed/22229868
(61) http://www.ncbi.nlm.nih.gov/pubmed/17698948
(62) http://www.ncbi.nlm.nih.gov/pubmed/23291610

The Best Weight Loss and Healthy recipe: Funky Monkey Smoothie

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 15.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The (safe, nutritious, easy to prepare snacks for any occasion) ultimate allergy-free snack cookbook by Judi and Shari Zucker, Square one publishers. Over 100 kid -friendly recipes for the allergic child.

Frozen Fruit or Ice Cubes?

The foundation of any smoothie i fruit or fruit juice that is often thickened with ice.ice. Instead of ice, you can use frozen fruit. Either buy fruit that is already frozen or freeze your own fresh varieties. Wash the fruit well dry, and then place it in a zip-lock freezer bag. This is an especially good idea for berries, which are not always in season and spoil quickly. Frozen, they can last for months.

Carob powder gives this thick, rich drink the delicious flavor of chocolate

Yield: 3 serving (about 8 ounce each)
1 tablespoon carob milk
2 cups rice milk
2 medium sized ripe banana, cut into small chunks
3 tablespoon honey or brown rice syrup
1 tablespoon vanilla
4-6 ice cubes

1. Place the carob powder and 2 tablespoon of the rice milk on a cup or small bowl and stir until the carob is dissolved. Transfer to a blender and add the remaining ingredients
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Overcome Infertility: Spermic Causes of Infertility

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

Spermic Causes of Infertility

1. Teraospermia
Teratospermia or teratozoospermia is a condition in which the sperm is mature abnormally such as th round headed spermatozoa affecting fertility in males by reducing sperm mobility and preventing sperm from penetrating into the egg.

2. Sperm agglutination
Sperm agglutination is a condition in which sperm clumping together due to infection or antibody reactions, thereby reducing the sperm's ability to fertilize egg and increasing the risk of infection.

3. Immature sperm
Sperm is manufactured in the testicles which are located in the scrotum. Immature sperm cells start to develop and grow in the seminiferous tubules then pass into the epididymis, where the sperm are stored and continue to grow and gain the ability to swim.

4. Necrozoospermia
Necrozoospermia is defined as the condition of totally absent sperm movement. The cause of necrozoospermia is still unknown. Some suggest it may be caused by a birth defect or obstructive pathology including hydrocoele, and varicocoele.

5. Oligospermia
Oligospermia is defined as a condition of having a low number of sperm during ejaculation of the male. It is caused by abnormal enlargement of the vein, sperm duct infection, or abnormal functioning of the pituitary gland in hormone secretion for production of sperm.

6. Klinefelter's syndrome
This is a genetic defect of the male with one Y chromosome and 2 X chromosomes leading to hormone imbalance, including lack of testosterone. Male breast, small testes and the interference with normal sperm production (semen found to have no sperm) causing infertility.

7. Germ cell phasia
As we known, the men's testicle contains germ cells for sperm production. Germ cell phasia is a genetic disease in men in which testicles have no germ cells thus are unable to produce sperm.

8. Epididymal obstruction
Epididymis is a tiny tube which attaches to the testicle. Epididymals obstruction is defined as the blockage of the passage of sperm to the penis leading to low sperm count and increases the risk of infertility.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Children Health: Attention Deficit Disorder (ADHD/ADD) - Diet for ADHD - Chicken

Attention Deficit Disorder (ADHD/ADD) also known as attention deficit hyperactivity disorder is a chronic disease occurs in certain age and years of a children, defined as a condition with characteristics of co-existence of attentional problems and hyperactivity. It effects about 5% of the all children in the world with boys have 3-4 times higher risk than girl. Over one third of children with ADHD will have continued symptoms existed into their adult life.

Diet for ADHD - Chicken

1. Vitamin B complex
a) Vitamin B2 or Riboflavin is one of very important vitamin in metabolism of energy by helping the transforming of fats, proteins and carbohydrates and high dose riboflavin appears to be useful alone or along with beta-blockers in the prevention of migraine, according to the study of "Effectiveness of high-doseriboflavin in migraine prophylaxis. A randomized controlled trial" by Schoenen J, Jacquy J, Lenaerts M. (60)

b) Vitamin B3
Vitamin B3 or Niacin is essential for lowering high cholesterol levels, according to the study of "Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib" by Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20448206), forming the components of cells' genetic material DNA during excision repair, according to the study of "Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow" by

Kostecki LM, Thomas M, Linford G, Lizotte M, Toxopeus L, Bartleman AP, Kirkland JB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/17618655) and treating diabetes and high blood sugar levels, according to the study of "Treatment of dyslipidemia in patients with type 2 diabetes" by Vijayaraghavan K., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21172030), researcher indicated that a number of lipid-lowering agents, including statins, fibrates, niacin, and bile acid sequestrants, are available to target normalization of the entire lipid profile.
c) Vitamin B6
c. 1. Vitamin B6 or Pyridoxine beside is important in enhancing the developing red blood cells by stimulating the production of hemoglobin, it also helps to keep blood sugar levels steady during the process of breaking down stored energy in gestation pregnancy, according to the study of "Improvement of oral glucose tolerance in gestational diabetes by pyridoxine" by Bennink HJ, Schreurs WH., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/1131652)

c.2. It also plays a pivotal role as a methyl donor in the basic cellular process ofmethylation, through which methyl groups are transferred from one molecule to another, resulting in the formation of a wide variety of precess, including regulation of gene expression, protein function, and RNA metabolism. When levels of B6 are inadequate, it may cause faulty Methylation with high levels of homocysteine that can cause variety of disease, including cervical dysplasia, faulty detoxification and impaired DNA repair, etc., according to the study of "Back To Life Natural Health Center - Healthcare Through Natural Methods"(http://www.backtolifehealth.com/Methylation.htm)

d) Vitamin B12In the evaluation of vitamin B12 in Turnip greens found that vitamin Bi2 was present in the
leaves of a higher plant in amounts. there is no evidence supporting the synthesis of vitamin Bi2 by a higher plant. Was it produced by soil microorganisms and subsequently absorbed via the plant roots? There is ample proof of such synthetic activity by certain microorganisms and of vitamin B12 activity in soil , but no evidence that the vitamin B]2molecule is absorbed by the plant from the soil. Could it have been produced by bacteria living epiphytically
on the turnip leaf? Ericson and Lewis ('54) postulated such a relationship in their studies of vitamin Bt2 compounds found in certain algae, according to "STUDIES OF VITAMIN B12IN TUENIP GREENS" by LOUISE F. GEAY ANDLOUISE J. DANIEL(http://jn.nutrition.org/content/67/4/623.full.pdf)

2. Protein
Protein beside is important building block of bones, muscles, cartilage, skin, and blood, it also enhances the nervous system in information transmitting between cells and cells of the other parts of the body, thus reducing the risk of nervous tension, (according to the study of "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function" by Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Abrous DN, Montcouquiol M, Sans N, posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20660256)

3. Iron
Beside as a mineral in carrying life-giving oxygen to human blood cells and maintaining robust health as an essential protein component for metabolism, it also helps in synthesis of a number of essential neurotransmitters like dopamine, nor-epinephrine, along with serotonin. acccording to the study of "Brain Iron Dysregulation and the Risk of Ageing White Matter Lesions" by Gebril OH, Simpson JE, Kirby J, Brayne C, Ince PG., posted in PubMed, researchers found that The mRNA expression using QPCR suggests a pattern that favours decreased intracellular iron influx, increased ferrous oxidation and increased iron export from the cells. Iron metabolism seems to be changed in brains with WML, increased elemental iron in these brains and in turn increased production of free oxidative radicals could represent a potentiating factor for the development of ageing WML.
Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Most Common Diseases of 50 Plus: Thyroid disease: Thyroid hormone resistance syndrome - The Symptoms

Thyroid disease

Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.

Thyroid hormone resistance syndrome

Thyroid hormone resistance syndrome is defined as a condition of which affected individuals have elevated serum thyroid hormone levels and inappropriately normal or elevated thyroid-stimulating hormone (TSH) but are usually clinically euthyroid and require no treatment. Selective pituitary resistance to thyroid hormone (PRTH) is characterized by resistance in the pituitary gland but not in peripheral tissues(a).

The Symptoms

1. hyperactivity, emotional lability, a below average intelligence quotient, and short stature
Thyroid hormone resistance mutations are associated with a wide variety of phenotypes and subsequent treatment challenges. Among the more common symptoms are hyperactivity, emotional lability, a below average intelligence quotient, and short stature(1).

2. Hyperthyroid symptoms
There is a first case report of a resistance to thyroid hormone in a neonate presenting with hyperthyroid symptoms born to a mother with Graves’ disease and treated with methimazole and iodine(2). such as Sudden weight loss, rapid heartbeat (tachycardia), increased appetite, nervousness, anxiety and irritability, tremor, etc(3).

3. Psychiatric disorders
There is a report of six children from five unrelated families with esistance to thyroid hormone (RTH). All patients grew normally and presented variable symptoms that were treated according to need. Two patients developed psychiatric disorders. Only one of the four affected parents exhibited clinical signs of RTH (tachycardia and depression)(4).

4. Other symptoms
According to the study by the Northwestern University Medical School,, clinical effects of RTH can include short stature, delayed bone maturation, hyperactivity, learning disabilities, and hearing defects, as well as variable features of hyper- and hypothyroidism(5).

Others indicated that RTH symptoms include failure to thrive, growth retardation and attention-deficit hyperactivity disorder in childhood, and goitre and thyrotoxic cardiac symptoms in adults(5a).