Saturday, August 20, 2016

Phytochemicals in Foods- The Effects of Theaflavin-3'-gallate

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                      Theaflavin-3'-gallate



Theaflavin-3'-gallate, a theaflavin derivative, is phytochemicals of Flavan-3-ols, in the group of Flavonoids (polyphenols) found abundantly in black tea.


Health benefits
1. Antioxidant capacities
In the comparison of TF derivatives (theaflavin (TF(1)), theaflavin-3-gallate(TF(2)A), theaflavin-3'-gallate (TF(2)B), and theaflavin-3,3'-digallate (TF(3))) in scavenging reactive oxygen species (ROS) in vitro, indicated that positive antioxidant capacities of TF(2)B on singlet oxygen, hydrogen peroxide, hydroxyl radical, and the hydroxyl radical-induced DNA damage in vitro were found, according to "Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses" by Wu YY, Li W, Xu Y, Jin EH, Tu YY.(1)

2. Antimicrobial activities
In the evaluation of the antimicrobial activities of seven green tea catechins and four black tea theaflavins, found that (-)-gallocatechin-3-gallate, (-)-epigallocatechin-3-gallate, (-)-catechin-3-gallate, (-)-epicatechin-3-gallate, theaflavin-3, 3'-digallate, theaflavin-3'-gallate, and theaflavin-3-gallate showed antimicrobial activities at nanomolar levels; (ii) most compounds were more active than were medicinal antibiotics, such as tetracycline or vancomycin, at comparable concentrations; (iii) the bactericidal activities of the teas could be accounted for by the levels of catechins and theaflavins as determined by high-pressure liquid chromatography; (iv) freshly prepared tea infusions were more active than day-old teas; and (v) tea catechins without gallate side chains, gallic acid and the alkaloids caffeine and theobromine also present in teas, and herbal (chamomile and peppermint) teas that contain no flavonoids are all inactive, according to "Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus" by Friedman M, Henika PR, Levin CE, Mandrell RE, Kozukue N.(2)

3. Edema, 4. anti inflammation
A single topical application of equimolar of black tea constituents (TF,theaflavin-3-gallate, theaflavin-3'-gallate, and theaflavin-3,3'-digallate) strongly inhibited TPA-induced edema of mouse ears. Application of TFs mixture to mouse ears 20 min prior to each TPA application once a day for 4 days inhibited TPA-induced persistent inflammation, as well as TPA-induced increase in IL-1beta and IL-6 protein levels. TFs also inhibited arachidonic acid (AA) metabolism via both cyclooxygenase (COX) and lipoxygenase pathways, according to "Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears" by Huang MT, Liu Y, Ramji D, Lo CY, Ghai G, Dushenkov S, Ho CT.(3)

5. Allergic effect
In the investigation of the preventive effects of black tea theaflavins, theaflavin-3-gallate (3-TF) and theaflavin-3,3'-digallate (TFDG), on oxazolone-induced type IV allergy in male ICR mice.
found that oral administration of 3-TF(theaflavin-3-gallate) and TFDG at a dose of 50 mg kg(-1) body weight prevented the increases in levels of some proinflammatory cytokines, interleukin-12 (IL-12), interferon-gamma (IFN-gamma), and tumour necrosis factor-alpha (TNF-alpha), according to "Preventive effects of black tea theaflavins against mouse type IV allergy" by Yoshino K, Yamazaki K, Sano M.(4)

6. Anti cancers
In the investigation of the inhibition effects of tea theaflavins complex (TFs),theaflavin-3-3'-digallate (TFDG), theaflavin-3'-gallate (TF2B), and an unidentified compound (UC) on the growth of human liver cancer BEL-7402 cells, gastric cancer MKN-28 cells and acute promyelocytic leukemia LH-60 cells, found that the inhibition effects of theaflavin-3'-gallate (TF2B), TFDG, and UC on BEL-7402 and MKN-28 were stronger than TFs. The relationship coefficients between monomer concentration and its inhibition rate against MKN-28 and BEL-7402 were 0.87 and 0.98 for TF2B, 0.96 and 0.98 for UC, respectively. The IC50 values of TFs, TF2B, and TFDG were 0.18, 0.11, and 0.16 mM on BEL-7402 cells, and 1.11, 0.22, and 0.25 mM on MKN-28 cells respectively, according to "The theaflavin monomers inhibit the cancer cells growth in vitro" by Tu YY, Tang AB, Watanabe N.(5)

7. Leukemia
in the investigation of the inhibitory effects of five tea polyphenols, namely theaflavin (TF1), theaflavin-3-gallate (TF2), theaflavin-3,3'-digallate (TF3), (-)-epigallocatechin-3-gallate (EGCG), and gallic acid, and propyl gallate (PG) on xanthine oxidase (XO) found that Tea polyphenols and PG all have potent inhibitory effects (>50%) on PMA-stimulated superoxide production at 20 approximately 50 microM in HL-60 cells. Gallic acid (GA) showed no inhibition under the same conditions. At 10 microM, only EGCG, TF3, and PG showed significant inhibition with potency of PG > EGCG > TF3, according to "Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3,3'-digallate, (-)-epigallocatechin-3-gallate, and propyl gallate" by Lin JK, Chen PC, Ho CT, Lin-Shiau SY.(6)

8. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21887850
(2) http://www.ncbi.nlm.nih.gov/pubmed/16496576
(3) http://www.ncbi.nlm.nih.gov/pubmed/16404705
(4) http://www.ncbi.nlm.nih.gov/pubmed/20597096
(5) http://www.ncbi.nlm.nih.gov/pubmed/15248026
(6) http://www.ncbi.nlm.nih.gov/pubmed/10898615

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Food Therapy: Nuts & Seeds - Flaxseeds(Linum usitatissimum)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

                             Flaxseeds(Linum usitatissimum)



Flax seed is native to the region of the eastern Mediterranean to India and also known as common flax or linseed. Flax is an erect annual plant, it can grow to 1.2 m tall. The leaves are 20–40 mm long and 3 mm broad.

Nutrients
1. Energy
2. Carbohydrates
3. Sugars
4. Dietary fiber
5. Omega 3 fatty acid
6. Protein
7. Thiamine (Vitamin B1)
8. Riboflavin (Vitamin B2)
9. Niacin (Vitamin B3)
10. Pantothenic acid (B5)
11. Vitamin B6
12. Folate (Vit. B9)
13. Vitamin C
14. Calcium
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc
20. Manganese
21.Copper
22. Etc.

Health Benefits
A. Health benefits according to studies
1. Diabetes and its complication
In the investigation of Flax and Pumpkin seeds mixture and its effect on diabetes found that Diet supplemented with Flax and Pumpkin seeds mixture ameliorated the antioxidant enzymes activities observed in diabetic rats and significantly decreased MDA levels. Kidney histological sections, showed glomerular hypertrophy and tubular dilatation. In DMS rats, these histopathological changes were less prominent, according to "Flax and Pumpkin seeds mixture ameliorates diabetic nephropathy in rats" by Makni M, Sefi M, Fetoui H, Garoui el M, Gargouri NK, Boudawara T, Zeghal N.(a)

2. Hyperlipidemia
In the examination of the effects of flax and sesame seeds mixture onHyperlipidemia
found that Diet supplemented with flax and sesame seeds mixture in pregnant diabetic rats ameliorated lipid parameters, antioxidant enzyme activities, level of reduced glutathione and significantly decreased malonaldialdehyde levels, according to "Dietary polyunsaturated fatty acid prevents hyperlipidemia and hepatic oxidant status in pregnant diabetic rats and their macrosomic offspring" by Makni M, Sefi M, Garoui el M, Fetoui H, Boudawara T, Zeghal N.(b)

3. Hypolipidemic and hepatoprotective effects
In the evaluation of a rich source of unsaturated fatty acids of Flax and pumpkinseedsand theirs anti-atherogenic and hepatoprotective activities. found that flaxand pumpkin seed mixture had anti-atherogenic and hepatoprotective effects which were probably mediated by unsaturated fatty acids present in seed mixture, according to "Hypolipidemic and hepatoprotective effects of flax and pumpkin seed mixture rich in omega-3 and omega-6 fatty acids in hypercholesterolemic rats" by Makni M, Fetoui H, Gargouri NK, Garoui el M, Jaber H, Makni J, Boudawara T, Zeghal N.(c)

4. Cardiovascular diseases
In the research of Flaxseed and its effect on cardiovascular risk found thatflaxseed can modestly reduce serum total and low-density lipoprotein cholesterol concentrations, reduce postprandial glucose absorption, decrease some markers of inflammation, and raise serum levels of the omega-3 fatty acids, ALA and eicosapentaenoic acid. Data on the antiplatelet, antioxidant, and hypotensive effects of flaxseed, however, are inconclusive. More research is needed to define the role of this functional food in reducing cardiovascular risk, according to "Flaxseed and cardiovascular risk' by Bloedon LT, Szapary PO.(d)

5. Hypercholesterolemic atherosclerosis
In the evaluation of Flaxseed (Type I flaxseed) and CDC-flaxseed (Type II flaxseed) and theirs effect onhypercholesterolemic atherosclerosis found that Type II flaxseed reduced the development of atherosclerosis by 69%, according to "Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid" by Prasad K, Mantha SV, Muir AD, Westcott ND.(e)

6. Anti- hormono-dependant cancers
In the observation of Flax lignans belonging to the phytoestrogens, metabolised after ingestion into enterolignans and its protective effect against the onset and development of hormono-dependant cancers found that in vitro studies based on mammalian cellular models tend to confirm their beneficial effects observed during epidemiological studies and give us insights about their mechanisms of action, according to "[Interest of lignans in prevention and treatment of cancers].[Article in French]" by Lamblin F, Hano C, Fliniaux O, Mesnard F, Fliniaux MA, Lainé E.(f)

7. Etc.

B. Health benefits according to concentration
1. Omega 3 fatty acidsBesides well known for its benefits for the maintenance of a healthy cardio-vascular system, according to the study of "Omega-3 Fatty acids for cardiovascular disease prevention" by Defilippis AP, Blaha MJ, Jacobson TA, posted in PubMed(I) and proper ratio of Omega 3 and 6 fatty acid and prevent blood clotting, it also extends the portion of your cycle in which you are fertile, by promoting natural ovulation, according tothe study of "Postpartum ovarian activity in multiparous Holstein cows treated with bovine somatotropin and fed n-3 fatty acids in early lactation" by Carriquiry M, Dahlen CR, Weber WJ, Lamb GC, Crooker BA., posted in pubMed (II)

2. ManganeseIt is one of important trace in preventing osteoporosis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(III)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(IV)

3. Vitamin B1
Vitamin B1 beside is important supplement used to treat inflammatory diseases, according to ""Protective role of benfotiamine, a fat-soluble vitamin B1analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages" by Yadav UC, Kalariya NM, Srivastava SK, Ramana KV.,(IVa), but also p;revent the risk of diabetic complication, according to "The potential role ofthiamine (vitamin B1) in diabetic complications" by Thornalley PJ.(IVb)

4. Dietary fiberDaily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(V)

5. MagnesiumMagnesium not only important for bone health, according to the study of "Magnesium, zinc, copper, manganese, and selenium levels in postmenopausal women with osteoporosis. Can magnesium play a key role in osteoporosis?" by Odabasi E, Turan M, Aydin A, Akay C, Kutlu M(VI) but also play and important role in protecting against Alzheimer's disease, according to the study of "Altered ionized magnesium levels in mild-to-moderate Alzheimer's disease" by Barbagallo M, Belvedere M, Di Bella G, Dominguez LJ.(VII)

6. TryptophanTryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(VIII)

7. Etc.
C. Other health benefits
1. Menstrual cramps and pain
Since flaxseed contains high amount of Omega 3 fatty acid, it promotes the proper ratio of Omega 6 fatty acid that reduces the abnormal cramps and pain caused by over production of prostaglandin hormone.

2. Diabetes
Flax contains high levels of lignans, which are natural compounds that help to improve the levels of glucose by by increasing glucose disposal rates and enhancing hepatic insulin sensitivity by working as a PPAR-γ agonist in type-2 diabetic rats., according to "The lignan-rich fractions of Fructus Schisandrae improve insulin sensitivity via the PPAR-γ pathways in in vitro and in vivo studies" by Kwon DY, Kim da S, Yang HJ, Park S(1)


3. Natural Laxative
Flaxseed contains high amount of insoluble fibers that combine with water to soften stool, induce bowel movement that helps to enhance the excretion of feces from the colon to prevent constipation, according to "Fiber and starchy foods: gut function and implications in disease" by Jenkins DJ, Jenkins AL, Wolever TM, Rao AV, Thompson LU.(2)

4. Free radicals
Flax seed contains a high amount of antioxidant that helps to guard the body from forming of free radicals by promoting the proper DNA replication and cells division, according to "Free radicals, metals and antioxidants in oxidative stress-induced cancer" by Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M.(3)

5. Heart diseases
High amount Omega 3 fatty acid also helps to treat for people with varicose veins, due to EPA and DHA by stimulating blood flow, increasing the breakdown of fibrin, a compound involved in clot and scar formation, according to "Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturatedomega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (OMEGA-PCI clot)" by Gajos G, Zalewski J, Rostoff P, Nessler J, Piwowarska W, Undas A.(4)

6. Etc.


Side Effect1. flax seed may cause less effectiveness of certain oral medications and upset hormonal balance if it is eaten in a large amount.
2. Etc.
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The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

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Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/20570704
(b) http://www.ncbi.nlm.nih.gov/pubmed/21458299
(c) http://www.ncbi.nlm.nih.gov/pubmed/18938206
(d) http://www.ncbi.nlm.nih.gov/pubmed/14995053
(e) http://www.ncbi.nlm.nih.gov/pubmed/9543108
(f) http://www.ncbi.nlm.nih.gov/pubmed/18466729

(I) http://www.ncbi.nlm.nih.gov/pubmed/20842560
(II) http://www.ncbi.nlm.nih.gov/pubmed?term=Postpartum%20ovarian%20activity%20in%20multiparous%20Holstein%20cows%20treated%20with%20bovine%20somatotropin%20and%20fed%20n-3%20fatty%20acids%20in%20early%20lactation
(III) http://www.ncbi.nlm.nih.gov/pubmed/12870295
(IV) http://www.ncbi.nlm.nih.gov/pubmed/22072339
(IVa) http://www.ncbi.nlm.nih.gov/pubmed/20219672
(IVb) http://www.ncbi.nlm.nih.gov/pubmed/18220605
(VI) http://www.ncbi.nlm.nih.gov/pubmed/22009132
(VII) http://www.ncbi.nlm.nih.gov/pubmed/21951617
(VIII) http://www.ncbi.nlm.nih.gov/pubmed/19539268

(1) http://www.ncbi.nlm.nih.gov/pubmed/21440615
(2) http://www.ncbi.nlm.nih.gov/pubmed/3020970
(3) http://www.ncbi.nlm.nih.gov/pubmed/16430879
(4) http://www.ncbi.nlm.nih.gov/pubmed/21617138
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Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Liu Ji Nu or hua Shi Dan (Herba Artemisiae Anomalae)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
          Liu Ji Nu or hua Shi Dan (Herba Artemisiae Anomalae)


Liu Ji Nu is also known as artemesia. The bitter nad warm herb has been used in TCM to treat blockage of menses, post partum pain due to blood stasis, injuries from impacts, etc., as its promotes circulation of Blood, enefits menstruation, eliminates Blood statsis, calms pain, etc., by enhancing the functions of hreat and spleen channels.

Ingredients
1. Saponin
2. Flavonoids
3. Coumarin
4. Sesquiterpenoids
5. Camphor
6. Etc.

Health Benefits
1. Antioxidant activities
In the investigation of antioxidant activities of 45 Chinese herbs that regulate blood circulation using the oxygen radical absorbance capacity (ORAC) assay, reported for the first time antioxidant properties of many Chinese herbs. High antioxidant herbs were identified as Spatholobus suberectus vine (1990 micromol TE/g), Sanguisorba officinalis root (1940 micromol TE/g), Agrimonia pilosa herb (1440 micromol TE/g), Artemisia anomala herb (1400 micromol TE/g), Salvia miltiorrhiza root (1320 micromol TE/g) and Nelembo nucifera leaf (1300 micromol TE/g). Antioxidant capacity appears to correlate with the flavors of herbs identified within the formal TCM classification system and may be a useful guide in describing their utility and biochemical mechanism of action(1).

2. Anti herpes simplex virus
In the evaluating the antiviral effect of 472 traditional medicinal herbs (comprising raw material 10 mg/ml), through both initial (qualitative) and repeated (quantitative) screens, on type 1 herpes simplex virus, showed that through repeated screens, 10 highly effective herbs were Aristolochia debilis, Artemisia anomala, Lindera strychnifolia, Patrinia villosa, Pinus massoniana, Prunella vulgaris, Pyrrosia lingua, Rhus chinensis, Sargussum fusiforme and Taraxacum mongolicum. Clinically, among the 78 cases of herpetic keratitis due to HSV1 treated by Pyrrosia lingua and Prunella vulgaris eye drops, a cure was effected in 38 and an improvement in 37, with 3 being of no benefit(2).

3. Anti-HSV-II
In the investigating the anti-HSV-II action of 500 herbs by determinations of the virus inhibition logarithm (VIL), among these effective herbs, 10 were aqueous extracts of Artemisia anomala, Centella asiatica, Epimedium Sagittatum, Hibiscus mutabilis, Hosta plantaginea, Hypericum japonicum, Inula japonica, Mosla punctata, Rhododendron simsii, and Rhus chinenses, while 3 were alcohol extracts of Epimedium Sagittatum, Hypericum japonicum, and Mosla punctata(3).

4. Etc.

Side Effects
1. Do not use the in case of diarrhea caused by spleen deficiency
2. 2. Do not use the the herb in newborn, children or if you are pregnant or
breast feeding with out approval first with the related field specialist
3. Do not use the herb in case of blood and qi deficiency
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/18955214
(2) http://www.ncbi.nlm.nih.gov/pubmed/2161714
(3) http://www.ncbi.nlm.nih.gov/pubmed/2550706





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Overcome Infertility: What Exhibits Hormone Imbalance to Cause Infertility

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                    Overcome Infertility 

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

       What Exhibits Hormone Imbalance to Cause Infertility


1. Aging
a) In men
When the men get older, the levels of testosterone start to drop and the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosteronescausing leading to many problems such as erectile and abnormal sperm production.
b) In women
At the age of 35 or older, some women start to enter the state of peri menopause, leading to irregular menstrual cycle as resulting of low levels of estrogen resulting ovarian inability to response to the FSH hormone and produce mature eggs.

2. Lifestyle
A good living lifestyle may be helpful for preventing diseases and preserve health, but times the good living lifestyle also a cause of hormone imbalance. Some women with unexplained infertility may be caused by exercise such as running or joking 10 km a day, playing tennis everyday which stimulate the brain primitive function causing hormone imbalance and absence of menstrual cycle because there are so much energy have been spent on daily sport there are nothing left for the function to produce eggs or sperm.

3. Thyroid diseases
a) Hyperthyroidism
It is defined as a condition in which our body produces too much thyroid hormone causing low levels of estrogen which can not trigger the production of LH then ovulation leading to infertility.
b) Hypothyroidism
Hypothyroisim is defined as very little thyroid hormone is produced by the thyroid gland leading to irregular ovulation and increasing production of prolactin causing production of immature eggs.

4. Heredity
Congenital adrenal hyperplasia which presents at birth, it affect both boy and girl alike. It efects adrenal gland to make the hormones cortisol and aldosterone leading to high levels of testosterone hormone.


5. Sluggish liver
Liver is important for regulating the balance of essential fatty acid. Our daily today contains more meats and high levels of saturated fat and trans fat, which interfere the liver function and leading to over production of certain hormone, disrupting the normal menstrual cycles and normal function of male reproductive organ such as erectile dysfunction.

6. Klinefelter's syndrome
Genetic male defect with one chormocome Y and 2 chromosome X. It causes levels of testosterone hormone leading to female pattern including enlarged breast, small penis and normal sperm production.

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Children Health: Attention Deficit Disorder (ADHD/ADD) - Diet for ADHD - Salmon

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Attention Deficit Disorder (ADHD/ADD)

Attention Deficit Disorder (ADHD/ADD) also known as attention deficit hyperactivity disorder is a chronic disease occurs in certain age and years of a children, defined as a condition with characteristics of co-existence of attentional problems and hyperactivity. It effects about 5% of the all children in the world with boys have 3-4 times higher risk than girl. Over one third of children with ADHD will have continued symptoms existed into their adult life.


             Diet for ADHD - Buckwheat

 1. Protein
In the research of the importance of dietary proteins influence body weight by affecting four targets for body weight regulation: satiety, thermogenesis, energy efficiency, and body composition, found that Ingestion of dietary proteins in diabetes type 1 exerts a delayed postprandial increase in blood glucose levels due to protein-induced stimulation of pancreatic glucagon secretion. Higher than minimal amounts of protein in the diet needed for nitrogen balance may play animportant role for the increasing number of elderly obese subjects in our industrialized societies, since proteins exert beneficial effects in the conditions of overweight, metabolic syndrome, cardiovascular risk factors, bone health, and sarcopenia. Adverse effects of increased dietary proteins have been observed in subjects with renal impairment- this problem is frequently observed in the elderly, hypertensive, and diabetic population. Nevertheless, dietary proteins deserve more attention than they have received in the past, according to "Dietary proteins in obesity and in diabetes" by Keller U.(65)

2. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol, thus reducing the risk of cholesterol inflammation according to the study of "In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation" by Wang S, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH., posted in PubMed (66) and forming of free radical in the heart cells, leading to heart diseases. It also reduces the risk of plaque forming in the arterial wall, thus also decreasing the risk of stoke, according to the study of "N-3 vs. saturated fatty acids: effects on the arterial wall" by Sudheendran S, Chang CC, Deckelbaum RJ., posted in PubMed (67)

9. Etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, 
particular in treatment of menstrual disorder in Women Health


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Most Common Diseases of 50 Plus: Thyroid disease: Thyroid hormone resistance syndrome - The Complications and diseases associated to

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                         Thyroid disease


Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.


             Thyroid hormone resistance syndrome

Thyroid hormone resistance syndrome is defined as a condition of which affected individuals have elevated serum thyroid hormone levels and inappropriately normal or elevated thyroid-stimulating hormone (TSH) but are usually clinically euthyroid and require no treatment. Selective pituitary resistance to thyroid hormone (PRTH) is characterized by resistance in the pituitary gland but not in peripheral tissues(a).

                      The Complications and diseases associated to 

The Complications
1. Growth retardation/short stature and skeletal dysplasia
There is a report of a first human cases (female, age 6 y; father and daughter, ages 47 and 11 y, respectively) with growth retardation/short stature, skeletal dysplasia, constipation, and defective thyroid receptor α (TRα)(14). 

2. Thyroxine excess and inappropriate TSH secretion
Resistance to thyroid hormone (RTH) is an uncommon inherited cause of hyperthyroxinemia with inappropriate TSH secretion, according to the study by the University of Cambridge, Addenbrooke’s Hospital, United Kingdom(15).

3. Cardiovascular risk
RTH patients show evidence in this study of increased augmentation index consistent with an increase in arterial stiffness compared with euthyroid controls. They also demonstrate elevated LDL-cholesterol levels. Both these measures may lead to increased cardiovascular risk(16).

 The Diseases associated to Thyroid hormone resistance
1. Differentiated thyroid cancer (DTC)
There are reports of four unusual cases of DTC associated with TSHoma (2 cases), RTH (1 case), and an elevated TSH of unknown etiology (1 case)(17).

2. A pituitary tumor
There is a report of a woman in whom the standard evaluation for inappropriate TSH secretion was insufficient to distinguish these entities. The patient had a low-normal TRH stimulation test and an unmeasurable alpha-glycoprotein subunit level; however, a pituitary magnetic resonance imaging (MRI) revealed an adenoma. More testing using a T3 suppression test supported a RTH diagnosis and a R438H mutation was found in the TR-beta gene. To our knowledge, this represents the first report of an apparently incidental pituitary adenoma in the setting of documented resistance to thyroid hormone. As such, it raises the question of whether RTH predisposes to pituitary hyperplasia and adenoma. development(18).

3. Papillary thyroid carcinoma
There is an association of thyroid hormone resistance syndrome and papillary thyroid carcinoma(19).
4. Immune thrombocytopenic purpura (ITP).

There is a report of a 9-year-old girl presented with ITP and features of hypothyroidism in the form of goiter and growth retardation. She was subsequently found to have RTH. High-dose thyroid hormone replacement was required to overcome the resistance that not only ameliorated the features of hypothyroidism but also brought an apparent remission of ITP(20).

5. Postpartum thyroiditis
there is a repopt of a report of a unique case of a woman affected by RTH, due to a novel mutation V283A in THRB, who experienced PPT with a severe thyrotoxic phase after both her pregnancies. The association between RTH and PPT has never been reported in the literature. In particular, the marked suppression of TSH occurring when levels of TH are particularly elevated is not a frequent condition during RTH(21).

6. Chronic thyroiditis
There is a report of the five-year medical history of a Japanese woman and her father with RTH and coincidental chronic thyroiditis(22). 

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Sources
(14) http://www.ncbi.nlm.nih.gov/pubmed/23940126
(15) http://www.ncbi.nlm.nih.gov/pubmed/7998483
(16) http://www.ncbi.nlm.nih.gov/pubmed/18803680
(17) http://www.ncbi.nlm.nih.gov/pubmed/23553855
(18) http://www.ncbi.nlm.nih.gov/pubmed/11327621
(19) http://www.ncbi.nlm.nih.gov/pubmed/23457315
(20) http://www.ncbi.nlm.nih.gov/pubmed/23382302
(21) http://www.ncbi.nlm.nih.gov/pubmed/23134553
(22) http://www.ncbi.nlm.nih.gov/pubmed/16723809
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Women Health: The Obesity and Breast cancer Research and Studies of Pre-diagnosis body mass index and survival after breast cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Pre-diagnosis body mass index and survival after breast cancer

Obese and underweight women who develop breast cancer may have poorer survival compared with normal-weight women. According to the study by the Division of Research, Kaiser Permanente, posted in PubMed, after a mean follow-up of 7.8 years, 2,140 deaths and 2,065 recurrences were documented. Both underweight (HR = 1.59; 95% CI: 1.18, 2.13) and morbidly obese women (HR = 1.81; 95% CI: 1.42, 2.32) had the greatest risk of overall mortality compared with normal weight (18.5-24.9 kg/m(2)) women. Severe obesity (HR = 1.09; 95% CI: 0.88, 1.36) and obesity (HR = 1.11; 95% CI: 0.97, 1.27) were related to small non-significant increased risks. Overweight (25.0-29.9 kg/m(2)) was not associated with any excess risk compared with normal weight. Similar associations were found for breast cancer death and non-breast cancer death but not recurrence. Women who were underweight and morbidly obese before breast cancer diagnosis were at the greatest risk of all-cause mortality. Morbidly obese women were also at increased risk of death from breast cancer. These results suggest that degree of obesity confers differential risk on survival.
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