Medical Advisor Journals

Thursday, September 22, 2016

Herbal therapy: Popular Herbal Wild Indigo (Baptisia tinctoria)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Wild Indigo (Baptisia tinctoria)

Wild indigo, a perennial plant, In the gensu Baptisia, belonging to the family Fabaceae, native to Eastern United States. The herb has been used in traditional medicine as immune stimulant antiseptic, laxative, emmenagogue and anti-parasitic agent and to treat colds and flu, liver diseases, infections of the ear, nose and throat, heal ulcers in the mouth, gingivitis etc.

Health Benefits
1. Immunobalancing
In the investigation of an allopathic herbal combined preparation containing Echinacea root, wild indigo root, and white cedar leaf tips (Echinaceae radix + Baptisiae tinctoriae radix + Thujae occidentalis herba = Esberitox N) effects, indicated that in a recent study compliant to GCP, the therapeutic superiority of the herbal immunomodulator over placebo was confirmed as statistically significant and clinically relevant. The present overview describes a model of the antigen-independent mode of action of phytoimmunomodulation ("immunobalancing"), according to "Efficacy and mode of action of an immunomodulator herbal preparation containing Echinacea, wild indigo, and white cedar" by Wüstenberg P, Henneicke-von Zepelin HH, Köhler G, Stammwitz U.(1)

2. Viral respiratory tract infections
In the comfirmation of the effect of the single active ingredients Echinaceae (purpureae et pallidae) radix, Baptisiae tinctoriae radix and Thujae occidentalis herba as well as of the combination Esberitox N has been verified in vitro, found that the efficacy for viral respiratory tract infections has been proven yet again in recent GCP-compliant, clinical studies (15, 17). Under the influence of the phytotherapeutic the duration of the illness decreased with a responder rate that was significantly higher than under placebo. The therapeutic benefit was even more pronounced, if the pharmaceutical was applied as early as possible. It has a high drug safety, according to "[Pharmacodynamic effects and clinical effectiveness of a combination of herbal substances comprised of Cone Flower, Wild Indigo and White Cedar].[Article in German]" by Köhler G, Bodinet C, Freudenstein J.(2)

3. Common cold
In the verification of the efficacy and safety of an herbal medication containing an extract of a mixture of Baptisiae tinctoriae radix, Echinaceae pallidae/purpureae radix and Thujae, occidentalis herba (SB-TOX) in the treatment of upper respiratory tract infections (URIs), found that A total of 91 adults (mean age 42.1 +/- 13.0 years) were randomised to receive 19.2 mg of SB-TOX (n=31), 9.6 mg SB-TOX (n=29) or placebo (n=31) three times daily for 3-12 days. Since a "running nose" is the main symptom of a common cold, the total number of facial tissues used throughout the clinical duration of their cold was the primary efficacy parameter. In the intention-to-treat analysis, this total number of tissues decreased with increasing extract dose. The slope across groups according to the Jonckheere test was significant (p = 0.0259). In the high-dose group, the standardised effect size delta/SD was 0.46 compared with placebo. Time to relevant improvement in cold symptoms (measured as the time until less than 30 tissues per day were used) was 1.1 days (95% CI 0.52; 1.67), 0.76 days (95% CI 0.28; 1.24) and 0.52 days (95% CI 0.22; 0.82) in the placebo, according to "A randomized, double-blind, placebo-controlled, clinical dose-response trial of an extract of Baptisia, Echinacea and Thuja for the treatment of patients with common cold" by Naser B, Lund B, Henneicke-von Zepelin HH, Köhler G, Lehmacher W, Scaglione F.(3)

4. Immunostimulating activities
In the identification of the effects of he water or alcaline-water extracts of Echinacea purpurea (L.) Moench and -angustifolia DC., Eupatorium cannabinum L. and -perfoliatum L., Chamomilla recutita (L.) (Rauscher), Calendula officinalis L.,Baptisia tinctoria (L.) R.B., Achyrocline satureoides DC., Arnica montana L., Sabal serrulata Roem et Schult. and Eleutherococcus senticosus Maxim. polysaccharide fractions with molecular weights in the range of 25 000 to 500 000, found that according to the granulocytes- and carbon clearance tests, showed significant immunostimulating activities. The isolated compounds belong to the group of water-soluble, acidic heteroglycanes. The linkages in the different polysaccharides do not represent a uniform structure type, according to "[Immunostimulant action of polysaccharides (heteroglycans) from higher plants. Preliminary communication].[Article in German]" by Wagner H, Proksch A, Riess-Maurer I, Vollmar A, Odenthal S, Stuppner H, Jurcic K, Le Turdu M, Heur YH.(4)

5. Anti cancers and diseases
In the determination of the relation between immunomodulatory and anti-tumour activities in many Chinese medicinal plants, found that the purification, characterization and structural elucidation of immunomodulatory polysaccharides from medicinal plants may have important implications in the immunotherapy of cancer and in the treatment of various other diseases, according to "Immunomodulatory and anti-tumour polysaccharides from medicinal plants" by Wong CK, Leung KN, Fung KP, Choy YM.(5)

6. Etc.

Side effects
1. Do not use the herb in new born, children, or if you are pregnant or breast feeding with out approval from the related field specialist.
2. Overdoses can cause nausea, vomiting, diarrhea, respiratory paralysis, etc.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/1382301
(1) http://www.ncbi.nlm.nih.gov/pubmed/10539093
(2) http://www.ncbi.nlm.nih.gov/pubmed/12244885
(3) http://www.ncbi.nlm.nih.gov/pubmed/16323289
(4) http://www.ncbi.nlm.nih.gov/pubmed/6541484
(5) http://www.ncbi.nlm.nih.gov/pubmed/7895893

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Ren Shen (Radix Ginseng)

Ren Shen (Radix Ginseng)

Ren Shen is also known as Gingshen. The smells aromatic, tastes sweet and slightly warm herbs had been used in TCM as improved immune system, Anti Cancer, Anti aging, Anti stress, etc. agent and to generates fluids and reduce thirst, for xinqixu (heart qi deficient) palpitations with instant sweating and anxiety, insomnia, dizziness/headache, forgetfulness, impotence, diabetes, bleeding in the vagina not during period, seizures in children, chronic weakness, etc. as it strongly tonifies Original Qi, tonifies the Spleen and the Lungs, promotes generation of Body Fluids, calms thirs and the Mind, etc. by enhancing the functions of spleen and lung channels.

Ingredients
1. Saponins
2. Panaxynol
3. Ginsenyne
4. Alpha pansinsene
5. Beta pansinsene
6. Beta farnesene
7. Bicyclogermacrene
8. Beta elemene
9. Gama elemene
10. Alpha neodovene
11. Beta neodovene
12. Alpha humulene
13. Beta humulene
14. Ccaryophyllene
15. Beta gurjunene
16. Alpha gurjunene
17. Alpha selinene
18. Beta selinene
19. Gama selinene
20. Selin-4, alpha guaiene
21. Gama cubebene
22. Beta patchoulene
23. Hepatadecanol-1
24. Etc.

Health Benefits
1. Erectile dysfunction
Panax ginseng has been used as yang promoting herb as it improves sexual desire, treat erectile dysfunction and impotent over thousands of year. In the investigation of the effectiveness of Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) for treating erectile dysfunction, found that A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P<0.05), whereas no significant improvement was observed in the placebo group (P>0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P<0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients, according to “Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction”by Kim TH, Jeon SH, Hahn EJ, Paek KY, Park JK, Youn NY, Lee HL.(1).

2. Antioxidant activity
In the evaluation of the extraction conditions of polysaccharides from the rhizomes of Panax japonicus C.A. Meyer and its antioxidant effect found that antioxidant activity exhibited Panax japonicus polysaccharides (PJP) had a good potential for antioxidant, according to “Optimization of polysaccharides from Panax japonicus C.A. Meyer by RSM and its anti-oxidant activity” by Wang R, Chen P, Jia F, Tang J, Ma F.(2).

3. Antipsychotic effect
In the investigation of Panax quinquefolium (PQ) and its significant neuroactive properties for its antipsychotic potential found that PQ blocked ketamine induced memory impairment in the passive avoidance paradigm. In the chronic studies, PQ reduced the ketamine induced enhanced immobility in the forced swim test and did not show extra-pyramidal side effects in bar test and wood block test of catalepsy. These behavioural effects were compared with standard drugs haloperidol and clozapine. Further PQ reduced DA and 5-HT content after chronic treatment, but not after acute administration, according to “Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice” by Chatterjee M, Singh S, Kumari R, Verma AK, Palit G.(3).

4. Anti-cancers
In the identification of Panax ginseng as a herb used in Asia for the prevention and treatment of various diseases, including cancer found that the results clearly indicate the structure-related activities in which the compound with less polar chemical structures possesses higher cytotoxic activity towards cancer cells, according to “The in vitro structure-related anti-cancer activity of ginsenosides and their derivatives” by Dong H, Bai LP, Wong VK, Zhou H, Wang JR, Liu Y, Jiang ZH, Liu L.(4).

5. Neuroprotective effect
In the analyzing Panax ginseng C.A. Meyer and its beneficial effects in cerebral ischemia and inhibition of the inflammatory cascade in sepsis found that Ginsenoside Rb1 (GRb1) partially inhibited the activation of nuclear factor-κB (NF-κB) pathway from 6 h to 72 h after ischemia and reperfusion onset, as determined by the expression of total and phosphorylated NF-κB/p65, inhibitor protein of κB (IκB)-α, and IκB-kinase complex (IKK)-α. All these results indicate that suppression of local inflammation after cerebral ischemia might be one mechanism that contributes to the neuroprotection of GRb1, according to “Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia” by Zhu J, Jiang Y, Wu L, Lu T, Xu G, Liu X.(5).

6. Immunological activities
In the study of Water-soluble ginseng oligosaccharides (designated as WGOS) with a degree of polymerization ranging from 2 to 10 were obtained from warm-water extract of Panax ginseng roots, found that WGOS were potent B and T-cell stimulators and WGOS-1 has the highest immunostimulating effect on lymphocyte proliferation among those purified fractions. It is hoped that the WGOS will be developed into functional food or medicine, according to “Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots” by Wan D, Jiao L, Yang H, Liu S.(6).

7. Breast cancer
In the investigation the anticancer effects of warming and relieving cold phlegm formula (, WRCP), a mixture composed of the aqueous extracts of Aconitum carmichaeli, Rhizoma bolbostemmatis, Phytolacca acinosa, Panax notoginseng, and Gekko swinhonis G ū enther, combined with 5-fluorouracil (5-FU) on human breast cancer found that the treatment combination of WRCP and 5-FU was more effective in the inhibition of tumor growth than either agent alone and may have potentially additional benefit in improving the general condition and immunity of the mice with human breast cancer cell implants, according to “Anticancer effects of 5-fluorouracil combined with warming and relieving cold phlegm formula on human breast cancer” by Wang XL, Ma F, Wu XZ(7).

8. Type 2 diabetes
In the researches of Red ginseng (RG, Panax ginseng C.A. Meyer) and its effect for treating type 2 diabetes mellitus (DM) found that the evidence for the effectiveness of RG in controlling glucose in type 2 DM is not convincing. Few included studies with various treatment regimens prohibit definitive conclusions. More rigorous studies are needed to clarify the effects of RG on this condition, according to “Red ginseng for type 2 diabetes mellitus: A systematic review of randomized controlled trials” by Kim S, Shin BC, Lee MS, Lee H, Ernst E.(8).

9. Metabolic cardiovascular disease
In the identification of several traditional Chinese medicine and teirs effect on metabolic cardiovascular disease, authors emphasized that the relationship among axis of excessive ROS/RNS-mitochondrial dysfunction-apoptosis-atherosclerosis. They also introduce several traditional Chinese medicines such as Ophiopogon japonicus, butin, Panax ginseng, Pueraria lobata, Solanum lyratum and so on in the treatment of relevant diseases through anti-ROS/RNS mechanism. Moreover, the TCMs also can anti-cancer and anti-fatigue,which show the speciality of TCMs different from the single effect of classical western medicines, according to “[Mitochondrial dysfunction induced by excessive ROS/RNS-metabolic cardiovascular disease and traditional Chinese medicines intervention].[Article in Chinese]” by Zhang C, Liu J, Pan H, Yang X, Bian K.(9).

10. Prostate hyperplasia
in the demonstration of Panax ginseng’s pharmacological activities on benign prostatic hyperplasia (BPH) found that 20(S)-Rg3 downregulated AR by facilitating the degradation of AR protein. WKRG and 20(S)-Rg3 were found to have new pharmacological activities against testosterone-induced prostate overgrowth. Given that red ginseng has been used safely in Asia for 1000 years, red ginseng and 20(S)-Rg3 could be potential therapeutic regimens for treating BPH, according to “Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling” by Bae JS, Park HS, Park JW, Li SH, Chun YS(10).

11. HL-60 cells
In the classification of Four new triterpene saponins, ginsenosides Rh (14)-Rh (17) ( 1- 4), along with two known compounds, 20( S)-ginsenoside Rg (2) and dammar-( E)-20(22),24-diene-3 β,6 α,12 β-triol, and theirs effect on HL-60 cells found that the isolated compounds were tested for IN VITRO cytotoxicity against HL-60 cells, according to “Four New Dammarane-Type Triterpene Saponins from the Stems and Leaves of Panax ginseng and Their Cytotoxicity on HL-60 Cells” by Li KK, Yao CM, Yang XW.(11).

12. Wound healing
In the investigation of herbal drugs (Panax ginseng, beta-sitosterol from Aloe vera, calycosin from Radix Astragali, and extracts from Hippophae rhamnoides L. and Angelica sinensis.) and theirs effect on wound healing indicated that the use of plants and their extracts as potential therapeutic agents with pro- or antiangiogenic activity. Since the anticancer and antiangiogenic properties of many phytomedicines have been amply reviewed elsewhere this paper will focus on the treatment of vascular insufficiency in wound healing, according to “Proangiogenic activity of plant extracts in accelerating wound healing – a new face of old phytomedicines” byMajewska I, Gendaszewska-Darmach E.(12).

13. Cardiovascular Disorders
In the evaluation of plethora of pharmacological properties of North American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng) found that Experimental studies have revealed a number of beneficial properties of ginseng, particularly in the area of cardiac protection, where ginseng and ginsenosides have been shown to protect the ischaemic and reperfused heart in a variety of experimental models. Emerging evidence also suggests that ginseng attenuates myocardial hypertrophy, thus blunting the remodelling and heart failure processes. However, clinical evidence of efficacy is not convincing, likely owing primarily to the paucity of well designed, randomized, controlled clinical trials, according to “Therapeutic Potential of Ginseng in the Management of Cardiovascular Disorders” by Karmazyn M, Moey M, Gan XT.(13).

14. Atherosclerosis
In the association of the herbal remedies on the prevention and treatment of AS found that mixed herbal preparations with multiple active ingredients may be preferable for the prevention and treatment of AS. Further rigorously designed pharmacological evaluation and multi-centred clinical trials are warranted, according to “Herbal Remedies Supply a Novel Prospect for the Treatment of Atherosclerosis: A Review of Current Mechanism Studies” by Zeng Y, Song JX, Shen XC.(14).

Side Effects
1. Overdoses can cause toxicity such as headaches, insomnia, anxiety, elevated blood pressure, rapid respiration and Oral dosage of 200 ml of saponins may cause allergic reactions of rash, itchiness, dizziness, headache, rising of body temperature and bleeding
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Phytochemicals for Treatment of Polymalagia Arthritis(PMR)

Phytochemials are defined as a group of chemical compound found naturally in plants, including fruits, vegetables, beans, grains, etc. Many studies have proven that they can because of certain phytochemicals, but for what ever reason, there are either no clinical trials follow through or the studies can not make to stage of clinical trials. Do not expect the pharmateutical or foods industrial companies to pay for the researches, as the discovery of the phytochemicals to cure cancers can only dampen the profits of both industries as phytochemicals can not be patented.

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
Food intake can help to prevent and treat cancers.

Treatment of Polymalagia Arthritis(PMR)

Polymalagia Arthritis is defined as a condition a common inflammatory rheumatic disease which cause pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures, causing musculoskeletal symptoms in PMR.

Foods to prevent and treat Polymalagia Arthritis(PMR)
1. Organic Whole foods Soy
In the study to examine the role of TK activity on the expression of the inducible nitric oxide (NO) synthase (iNOS), found that TK inhibition by genistein had no effect on the expression or nuclear translocation of the transcription factors interferon regulatory factor-1 and nuclear factor-KB, respectively, both of which have been implicated in transcriptional regulation of the human iNOS gene. Nuclear run-on analysis demonstrated that the effect of genistein on iNOS messenger RNA expression was not at the level of transcription, suggesting that posttranscriptional regulation of iNOS messenger RNA might be TK dependent.Isoflavones, such as genistein, are useful tools to dissect regulatory pathways in vitro and in vivo and may have potential use as novel antiinflammatory therapeutic agents(1).

2. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
a. Immune system
a. 1. In the investigation of the immunomodulatory effects of decaffeinated greentea extract in rain bow of the study of "Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss)" by Sheikhzadeh N, Nofouzi K, Delazar A, Oushani AK.(32), researchers found that showed that decaffeinated green tea in lower doses of administration could be optimum to enhance the immunity of rainbow trout(2).

a.2. In the investigation of Green tea and Arthritis of the study of "Green teapolyphenol epigallocatechin 3-gallate in arthritis" by Ahmed S., researcher indicated that although these findings provide scientific evidence of the anti-rheumatic activity of EGCG, further preclinical studies are warranted before phase clinical trials could be initiated with confidence for patients with joint diseases(3).

3. Olive oil
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.
a. Olive oil phenolics
In the evaluation of the olive oil phenolics of the Mediterranean diet and its lower incidence of atherosclerosis, cardiovascular disease, and certain types of cancer, found that olive oil phenolics have positive effects on certain physiological parameters, such as plasma lipoproteins, oxidative damage, inflammatory markers, platelet and cellular function, and antimicrobial activity, according to "Chemistry and health of olive oil phenolics" by Cicerale S, Conlan XA, Sinclair AJ, Keast RS.(4)

b. Antioxidants and weight loss
In the analyzing the influence of a Mediterranean dietary pattern on plasma total antioxidant capacity (TAC) found that Mediterranean diet, especially rich in virginolive oil, is associated with higher levels of plasma antioxidant capacity. Plasma TAC is related to a reduction in body weight after 3 years of intervention in a highcardiovascular risk population with a Mediterranean-style diet rich in virgin olive oil, according to "A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain" by Razquin C, Martinez JA, Martinez-Gonzalez MA, Mitjavila MT, Estruch R, Marti A.(5)

4. Salmon
a. Antioxidants
In the research of the antioxidant effect of vitamin E after ingestion of salmon found that that megadoses of vitamin E, far from having pro-oxidative activity, actually increase the anti-oxidative capacity of the liver, especially after ingestion of salmon oil, according to "Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil" by Flader D, Brandsch C, Hirche F, Eder K.(6)

b. Selenium
Salmon contains trace minerals selenium which is essential for the healthy function of the thyroid and immune system as it increases the antioxidant defense system by fighting against the forming of free radicals and reduce the risk of irregular cells growth causes of tumor and cancer, according to the study of "Selenium in the immune system" by Arthur JR, McKenzie RC, Beckett GJ.,(7)

c. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol, thus reducing the risk of cholesterol inflammation according to the study of "In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation" by Wang S, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH., posted in PubMed (IV) and forming of free radical in the heart cells, leading to heart diseases. It also reduces the risk of plaque forming in the arterial wall, thus also decreasing the risk of stoke, according to the study of "N-3 vs. saturated fatty acids: effects on the arterial wall" by Sudheendran S, Chang CC, Deckelbaum RJ., posted in PubMed (8).

5. Circuit fruits
Circuit fruit contain high amount of Quercetin which can reduce the risk of Rheumatoid Arthritis as a result of anti inflammatory and antioxidant effects
a. Anti-Inflammatory
According to the study of `Antioxidant and Anti-Inflammatory Activities ofQuercetin 7-O-β-D-Glucopyranoside from the Leaves of Brasenia schreberi.`by Legault J, Perron T, Mshvildadze V, Girard-Lalancette K, Perron S, Laprise C, Sirois P, Pichette A. (Source from Laboratory for Analysis and Separation of Plant Species (LASEVE), Université du Québec à Chicoutimi , Chicoutimi, Québec, Canada.), posted in PubMed, researchers found that some flavonoids have been reported to possess beneficial effects in cardiovascular and chronic inflammatory diseases associated with overproduction of nitric oxide. Quercetin-7-O-β-D-glucopyranoside possesses anti-inflammatory activity, inhibiting expression of inducible nitric oxide synthase and release of nitric oxide by lipopolysaccharide-stimulated RAW 264.7 macrophages in a dose-dependent manner. Quercetin-7-O-β-D-glucopyranoside also inhibited overexpression of cyclooxygenase-2 and granulocyte macrophage-colony-stimulating factor.

b. Free radical scavenger
In a study of `Dietary chromones as antioxidant agents-the structural variable.`by Dias MM, Machado NF, Marques MP. (Source from Research Unit "Molecular Physical Chemistry", University of Coimbra, Portugal.), posted in PubMed, researchers found that from the eighteen tested compounds, three-fisetin, luteolin and quercetin-are shown to act as effective antiradicals. Consistent structure-activity relationships (SARs) were established regarding the antioxidant role of this type of chromone-based system.

6. Turmeric
Turmeric, principal curcuminoid of the popular Indian spice, a rhizomatousherbaceous perennial plant of the ginger family, Zingiberaceae, native to tropicalSouth Asia.
a. Anti inflammatory effects
In a systematic review of the literature was to summarize the literature on the safety and anti-inflammatory activity of curcumin, found that curcumin has been demonstrated to be safe in six human trials and has demonstrated anti-inflammatory activity. It may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation, according to "Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)" by Chainani-Wu N (9)
b. Antioxidants
In the research of a literature search (PubMed) of almost 1500 papers dealing with curcumin, most from recent years, with ll available abstracts were read and pproximately 300 full papers were reviewed, found that curcumin, a component of turmeric, has been shown to be non-toxic, to have antioxidant activity, and to inhibit such mediators of inflammation as NFkappaB, cyclooxygenase-2 (COX-2), lipooxygenase (LOX), and inducible nitric oxide synthase (iNOS). Significant preventive and/or curative effects have been observed in experimental animal models of a number of diseases, including arteriosclerosis, cancer, diabetes, respiratory, hepatic, pancreatic, intestinal and gastric diseases, neurodegenerative and eye diseases, "Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases" by Bengmark S.(10)

7. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19281374
(2) http://www.ncbi.nlm.nih.gov/pubmed/21985858
(3) http://www.ncbi.nlm.nih.gov/pubmed/20447316
(4) http://www.ncbi.nlm.nih.gov/pubmed/19093267
(5) http://www.ncbi.nlm.nih.gov/pubmed/19707219
(6) http://www.ncbi.nlm.nih.gov/pubmed/18577222
(7) http://www.ncbi.nlm.nih.gov/pubmed/12730442
(8) http://www.ncbi.nlm.nih.gov/pubmed/20207121
(9) http://www.ncbi.nlm.nih.gov/pubmed/12676044
(10) http://www.ncbi.nlm.nih.gov/pubmed/16387899

Children's Health - Autism - Treatment with Animal therapy in a Conventional Medicine Perspective

Autism is one of the most common forms of brain development disorder and one in 166 child is diagnosed with some forms of autism. Children who are diagnosed with autism tend to have weak immune system and auto immune problems. Autism is defined as medical condition in which a child has some of the following impairments
a) Speech
b) Social and communication skills
c) Limited interest
d) Repetitive behaviour

Treatment with Animal therapy in a Conventional Medicine

Animal therapy focus to improve in the inter action between the child and animal, thereby increasing the child confident in building relation ship as well as sensory and motor issues.

Chinese Food Therapy
The Best Way to prevent, treat your disease,
particular in treatment of menstrual disorder in Women Health

Overcome Infertility: Gonadotrophin-releasing hormone (GnRH) Effects in Female Infertility

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

Gonadotrophin-releasing hormone (GnRH) Effects in Female Infertility

I. Definition
Gonadotrophin-releasing hormone (GnRH) is a synthesis GnRH hormone which helps to replace or increase the levels of GnRH in stimulating the production of LH and FSH by the pituitary gland

II. How Gonadotrophin-releasing hormone effects infertile women
GnRH may be used for infertile women, after HCG and ovulation dysfunction medication have been failed to stimulate the women reproductive ovulation. The process of LH and FSH production are controlled by the size and frequency of GnRH pulses.

1. Ovulation
At the begining, synthesis GnRH stimulates the low frequency GnRH pulses that cause the pitiutary gland to release FSH that helps to stimulate ovulation and the production of follicle and egg.
2. Egg Extrading
As the follicle mature, synthesis GrNH helps to increase the production of estradiol that stimulates the high frequency GrRH pulses and stops the putuitary in secreting FSH and increases the production of LH leading to egg releasing into the Fallopian tube.

3. Side effects
a) Hot flashes.
b) Mood swings.
c) Vaginal dryness.
d) Decreased sexual interest.
e) Insomnia.
f) Headaches.

4. Risk
a) Bone loss
b) Heart disease
Raising the level of LDL cholesterol and decreasing your HDL cholesterol.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

General Health: Duodenal ulcers: The Phytochemicals

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Duodenal ulcers

Duodenal ulcers, a type of peptic ulcer is defined as a condition of a localized tissue erosion in the lining the duodenum as a result of bacteria Helicobacter pylori (H pylori) in most cases. According to the study by Department of Research, University Hospital, Basel, fasting gastrin and pepsinogen-I and -II concentrations were significantly higher in H pylori positive compared with H pylori negative subjects. Neither age nor sex affected basal gastrin and pepsinogen concentrations in H pylori negative subjects. Fasting gastrin, pepsinogen-I and -II concentrations in serum samples were similar in H pylori positive persons with no symptoms and those with duodenal ulcers suggesting that similar mechanisms are involved in increasing plasma concentrations of these variables in both populations. Hypergastrinaemia and hyperpepsinogenaemia are therefore probably secondary to active H pylori infection(1).

The Phytochemicals

Plants and phytoconstituents are the better choice to treat diseases than the allopathic drugs. Most of the drugs used in primitive medicine were originated from plants and are the earliest and principal natural source of medicines. The drugs from plants are fairly innocuous and relatively free from toxic effects(22).
1. Fructans
Fructans found abundantly in onion, are small carbohydrate molecules that help maintain gastrointestinal health by sustaining beneficial bacteria(23).

2. Phenols
Polyphenols display a number of pharmacological properties in the GIT area, acting as antisecretory, cytoprotective, and antioxidant agents. The antioxidant properties of phenolic compounds have been widely studied, but it has become clear that their mechanisms of action go beyond the modulation of oxidative stress. Various polyphenolic compounds have been reported for their anti-ulcerogenic activity with a good level of gastric protection(24). Other indicated that the antimicrobial activity was greater in extract mixtures than in individual extracts of each species. The results also indicate that the synergistic contribution of oregano and cranberry phenolics may be more important for inhibition than any species-specific phenolic concentration(25).

3. Anthocyanins
Edible berries, a potential source of natural anthocyanin antioxidants, have demonstrated a broad spectrum of biomedical functions. In the study by InterHealth Research Center, showed that OptiBerry exhibits high antioxidant efficacy as shown by its high oxygen radical absorbance capacity (ORAC) values, novel antiangiogenic and antiatherosclerotic activities, and potential cytotoxicity towards Helicobacter pylori, a noxious pathogen responsible for various gastrointestinal disorders including duodenal ulcer and gastric cancer, as compared to individual berry extracts. OptiBerry also significantly inhibited basal MCP-1 and inducible NF-kappabeta transcriptions as well as the inflammatory biomarker IL-8, and significantly reduced the ability to form hemangioma and markedly decreased EOMA cell-induced tumor growth in an in vivo model(26).

4. Triterpenes
In study of the extracted isolation of Eugenia umbelliflora Berg. (Myrtaceae): taraxerol, alpha-amyrin, beta-amyrin, betulin and betulinic acid from the leaves, as well as trimethoxy ellagic acid from the fruitshe extracts of Eugenia umbelliflora Berg. (Myrtaceae), found that E. umbelliflora leaves display gastro-protective activity, as demonstrated by significant inhibition of ulcer formation in the different models. The results suggest that the gastroprotective activity may be attributed, at least in part, to the triterpenes(27).

5. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Sources
(22) http://onions-usa.org/img/site_specific/uploads/phytochemical_brochure.pdf
(23) http://onions-usa.org/img/site_specific/uploads/phytochemical_brochure.pdf
(24) http://www.ncbi.nlm.nih.gov/pubmed/21966156
(25) http://www.ncbi.nlm.nih.gov/pubmed/16332847
(26) http://www.ncbi.nlm.nih.gov/pubmed/17533652
(27) http://www.ncbi.nlm.nih.gov/pubmed/19731591

General Health: Eating Disorders - Anorexia nervosa - The Complications

Anorexia nervosa

Anorexia nervosa is a type of eating disorder usually develop in the teen years and effect over 90% of female, because of excessive food restriction and irrational fear to become fat due the wrongly influenced media as attractiveness is equated to thinness.

The Complications

Anorexia nervosa may cause severe complications in every major organ system in the body as a result of malnutrition due to self-imposed starvation.
A.1. Dermatologic signs of anorexia nervosa
Some researchers suggested that Dermatologic symptoms are almost always detectable in patients with severe anorexia nervosa (AN) and bulimia nervosa(BN), and awareness of these may help in the early diagnosis of hidden AN or BN. These manifestations include xerosis, lanugo-like body hair, telogen effluvium, carotenoderma, acne, hyperpigmentation, seborrheic dermatitis, acrocyanosis, perniosis, petechiae, livedo reticularis, interdigital intertrigo, paronychia, generalized pruritus, acquired striae distensae, slower wound healing, prurigo pigmentosa, edema, linear erythema craquele, acral coldness, pellagra, scurvy, and acrodermatitis enteropathica(21). Other suggested that the most frequent skin manifestations were xerosis (58.3%), hair effluvium (50%), nail changes (45.8%), cheilitis (41.6%), acne (41.6%), gingivitis (33.3%), acrocyanosis (29%), diffuse hypertrichosis (25%),carotenoderma (20.8%), generalized pruritus (16.6%), hyperpigmentation (12.5%), striae distensae (12.5%), factitial dermatitis, seborrheic dermatitis (8.3%), poor wound healing, melasma and Russell's sign (4.1%). In the patients with the bulimic type of AN, hair effluvium, acne, gingivitis, nail changes and generalized pruritus were more frequent than in the patients with the restrictive type(22).

A.2. Possible medical complications of anorexia nervosa
In the study of Eating disorders. A review and update, Dr. Haller E. at the University of California, indicated that Patients with eating disorders are usually secretive and often come to the attention of physicians only at the insistence of others. Practitioners also should be alert for medical complications includinghypothermia, edema, hypotension, bradycardia, infertility, and osteoporosis inpatients with anorexia nervosa and fluid or electrolyte imbalance,hyperamylasemia, gastritis, esophagitis, gastric dilation, edema, dental erosion,swollen parotid glands, and gingivitis in patients with bulimia nervosa. Treatment involves combining individual, behavioral, group, and family therapy with, possibly, psychopharmaceuticals. Primary care professionals are frequently the first to evaluate these patients, and their encouragement and support may help patientsaccept treatment. The treatment proceeds most smoothly if the primary care physician and psychiatrist work collaboratively with clear and frequent communication(23).

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Sources
(22) http://www.ncbi.nlm.nih.gov/pubmed/20808514
(23) http://www.ncbi.nlm.nih.gov/pubmed/1475950

Medical Advisor Journals

Pages

Natural Medicine for Fatty Liver And Obesity Reversal

Thursday, September 22, 2016

Herbal therapy: Popular Herbal Wild Indigo (Baptisia tinctoria)

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Ren Shen (Radix Ginseng)

Phytochemicals for Treatment of Polymalagia Arthritis(PMR)

Children's Health - Autism - Treatment with Animal therapy in a Conventional Medicine Perspective

Overcome Infertility: Gonadotrophin-releasing hormone (GnRH) Effects in Female Infertility

General Health: Duodenal ulcers: The Phytochemicals

General Health: Eating Disorders - Anorexia nervosa - The Complications