Sunday, October 21, 2018

The Magic Bean That Processes Anti Chronic Diseases' Activities



The use of plants for healing purposes has been predated long before the existence of modern medicine.
A recent study suggested a regular intake of kidney bean may have a potential effect in the prevention and treatment of chronic diseases.

Chronic diseases are medical conditions that last more than 3 months or more and can not be cured.

According to WHO in the article of "Noncommunicable diseases" suggested, "The four main types of noncommunicable diseases are cardiovascular diseases (like heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructed pulmonary disease and asthma) and diabetes"(4).

Some chronic conditions also are correlated with other diseases, such as chronic conditions of high blood cholesterol and pressure are associated to increase the risk of heart attack and stroke.

According to the Center for diseases control and prevention statistic, approximately, over 117 million people worldwide had one or more chronic health conditions. And 1 in 4 adults had two or more chronic health conditions(5).

The chronic diseases are the 7th most common causes of death in 2014(5).

Although most common causes of the chronic condition are either debatable or depending on types of condition. However, some researchers suggested that physical activity, poor nutrition, tobacco use, and excessive alcohol drinking are the most common risk factors.

Chronic diseases today have become a burden of the health care system, according to CDC. In the US, the conditions cost over 68% of annual health care expenditures of $2.7 trillion(5).


Depending on types of chronic condition, patients may experience some correlated symptoms
* In Patients with cardiovascular diseases, the symptoms include chest pain, chest tightness, chest pressure and chest discomfort (angina),....and shortness of breath.

* Depending to types of cancer, symptoms may including blood in the urine, hoarseness, persistent lumps or swollen glands. ... and indigestion or difficulty swallowing.

* Patients with chronic respiratory diseases may experience shortness of breath, especially during physical activities, wheezing,... and chest tightness.

* Patients with diabetes may include symptoms of unusual thirst, frequent urination, weight change,........ and extreme fatigue or lack of energy.

Kidney bean is very popular because of its kidney shape, strong flavor, and color of reddish brown in nature. The bean often is an excellent dietary selection with no cholesterol, but a good source of protein and minerals.

According to the University of Colorado Colorado Springs, consumption of kidney bean regularly attenuated the increased glycaemic stress (hyperglycemia and hyperinsulinemia) including diabetes, CVD and cancer.

Dr. Hutchins AM, the lead author said, " (The efficacy of kidney in reduced risk of chronic illness may be attributed to the) glycaemic response and the impact that relationship may have on the risk of developing diabetes, CVD and cancer".

In the study to compared two different illumination conditions during germination (12 h light/12 h dark vs 24 h dark) in lentils (Lensculinaris L.) and kidney beans (Phaseolus vulgaris L.), melatonin content exerted a significantly antioxidant activity in protection against free radicals as well as showing the use of food as preventive strategies in combating chronic diseases through the diet.

Furthermore, the investigation of phenolic-rich extracts obtained from two kinds of common beans, white kidney beans (WKB) and round purple beans (RPB), extracts Phenolic acids and phenolic compounds expressed strong antioxidants and anti-inflammatory activities in reduced the incidence of several chronic diseases that share an inflammatory component.


Dr. García-Lafuente A, the lead researcher in the study said, "common bean extracts may be used as a source of anti-inflammatory agents as well as a dietary complement for health promotion".


Taking together, intake kidney beans regularly may reduce risk and progression of chronic illness through the immunomodulatory effects involved increased antioxidant and ameliorated inflammatory activities.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects by Hutchins AM1, Winham DM, Thompson SV.(PubMed)
(2) Effect of illumination on the content of melatonin, phenolic compounds, and antioxidant activity during germination of lentils (Lens culinaris L.) and kidney beans (Phaseolus vulgaris L.) by Aguilera Y1, Liébana R, Herrera T, Rebollo-Hernanz M, Sanchez-Puelles C, Benítez V, Martín-Cabrejas MA.(PubMed)
(3) In vitro anti-inflammatory activity of phenolic rich extracts from white and red common beans by García-Lafuente A1, Moro C2, Manchón N2, Gonzalo-Ruiz A3, Villares A2, Guillamón E2, Rostagno M2, Mateo-Vivaracho L2.(PubMed)
(4) Noncommunicable diseases by WHO
(5) Chronic Diseases: The Leading Causes of Death and Disability in the United States(CDC)

Saturday, October 20, 2018

How to Prevent Immune Disorder, Cardiac and Infectious Diseases Caused By Thrombosis Naturally


Fennel may have a potential and positive effect to act as antithrombotic medicine in reduced hyper blood coagulation in initiated some forms of immune disorder, cardiac and infectious diseases, some scientists suggested.

Coagulation abnormalities are common medical conditions associated to patients in critical illness.
Dr. de Laforcade A, in the article "Diseases associated with thrombosis" said, "Traditionally, clinically relevant coagulation disorders have consisted mostly of bleeding associated with advanced stages of disseminated intravascular coagulation or toxin ingestion" and "Targeting those populations most at risk for thrombotic complications are necessary for better understanding the need for prophylactic anticoagulant therapy.".


According to medical literature, the function of the antithrombotic agent used in conventional medicine can be divided into 2 categories, for the prevention or treatment of a dangerous blood clot (acute thrombus) therapeutically.

Blood coagulation is very dangerous if it is untreated.

People who are hypercoagulable are associated to increase risk of blood clots developing in the arteries (blood vessels that carry blood away from the heart) and veins (blood vessels that carry blood to the heart), leading to stroke(4), heart attack(5), severe hip and leg pain(6), difficulty walking(7),...... epidemiological studies strongly suggested.

In-depth analysis, complications of untreated thrombosis are broader than general belief, including many forms of the immune-mediated disease, cardiac disease and infectious diseases(9).


Some researchers suggested that implications for communicating about family history of thrombosis may be necessary as it is one of the common risk factors in the increased onset of the condition.

People having the above symptoms together with the family history of blood clot should be diagnosed early to confirm or rule out such condition.

Early diagnosis of thrombosis is associated to increase survival and reduce the risk of complications.

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...


In the screen of the potential effect of essential oils extracted from fennel in guinea pig and rat plasma to assess antiplatelet activity and inhibition of clot retraction, researchers at the Università di Parma launched an investigation in compared a number of essential oil extracts from numbers of the herbal plant.

Including in the evaluation are essential oils isolated from Anthemis nobilis L., Artemisia dracunculus L., Cannabis sativa L., Cupressus sempervirens L., Cymbopogon citratus (DC.) Stapf., Curcuma longa L., Foeniculum vulgare L., Hypericum perforatum L., Hyssopus officinalis L., Mentha spicata L., Monarda didyma L., Ocimum basilicum L., Ocotea quixos Kosterm., Origanum vulgare L., Pinus nigra J.F. Arnold, Pinus silvestris L., Piper crassinervium Kunth., Rosmarinus officinalis L., Salvia officinalis L., Salvia sclarea L., Santolina chamaecyparissus L., Thymus vulgaris L., Zingiber officinaie L.

In compared to other essential oil, F. vulgaris essential oil exerted strong anti coagulative activities against ADP, Arachidonic Acid and the Thromboxane A2 agonist U46619, and a good ability to destabilize clot retraction.

Adenine di-Phosphate (ADP), an important platelet agonist that plays a vital role in normal hemostasis and thrombosis. The defective ADP may induce impairment of platelet aggregation.

Arachidonic acid is a polyunsaturated omega-6 fatty acid and the precursor of thromboxane and prostacyclin, two of the most active compounds related to platelet function.

Thromboxane A2 (TxA2) is a potent vasoconstrictor derived from the metabolism of arachidonic acid and has prothrombotic properties.
Further examination also found that tested essential oils, including fennel, demonstrate a significant correlation between antiplatelet potency and phenylpropanoids content.

The phenylpropanoids synthesized by plants from the amino acids phenylalanine and tyrosine are associated to the ability in inhibited blood clotting.

These results suggested that essential oils isolated from fennel and other herbal plants may play a key role for this moiety in the prevention of clot formation, Dr. Tognolini M, the lead author suggested, after taking into account of other co and confounders.

Moreover, anethole, the main fragrance and bioactive compound of fennel also exerted antithrombotic activity involved numbers of mechanisms others than those mentioned above.

According to the Università di Parma, the property of anethole in decreased thrombosis was attributed to the efficacy of the compound in modulated several cell signaling pathways, mainly NF-kB and TNF-α signaling.....

In thrombosis, NF-κB transcription factors, P50/P65 process the ability to regulate the expression of tissue factor (TF), a principal initiator of the coagulation cascade, according to the joint study led by the Institute of Biochemistry and Cell Biology(8).



Tumor necrosis factor is a cell signaling protein (cytokine) best known for its role in systemic inflammation and the acute phase reaction. The protein also plays an essential role in platelet thrombus formation.

The differentiation of anethole's role in decreased thrombosis suggested that activation of inflammatory cytokines by the immune system in the acute phase of infection also stimulates the production of platelets. And inflammatory cytokines also process the ability in enhanced the retraction of the coagulum.


In tested guinea pig, application of anethole enhanced antiplatelet properties through a significant effect in inhibited arachidonic acid, collagen, ADP and U46619-induced aggregation (IC(50) from 4 to 147 microg ml(-1)).

Researchers at Università di Parma also found that
*Anethole, tested in rat aorta with or without endothelium, displays a similar effect to those of NO-independent vasorelaxant activity at antiplatelet concentrations.
* . In vivo, anethole orally administered in a subacute treatment to mice (30 mg kg(-1)day(-1) for 5 days) showed significant antithrombotic activity in preventing the paralysis induced by collagen-epinephrine intravenous injection (70% and 83% protection, respectively).

After taking into account of other co and confounders, Dr. Tognolini M, the lead author at the Università di Parma said, "F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect and vasorelaxant action".



The findings indicated that fennel and its bioactive compound anethole may be considered as a functional food to reduce the risk of diseases associated to thrombosis, such as immune-mediated disease, neoplasia, systemic inflammation and sepsis, cardiac disease, protein-losing states, and infectious diseases(9).

However, further data collection on large sample size and multi centers clinical studies performed with human consumption during the course of the investigation will be necessary to complete the picture of fennel and its bioactive anethole' protective effect against onset thrombosis possibilities.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity by Tognolini M1, Barocelli E, Ballabeni V, Bruni R, Bianchi A, Chiavarini M, Impicciatore M(PubMed)
(2) Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis by Tognolini M1, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E.(PubMed)
(3) Anethole and Its Role in Chronic Diseases by Aprotosoaie AC1, Costache II2, Miron A3.(PubMed)
(4) Embolic middle cerebral artery occlusion (MCAO) for ischemic stroke with homologous bloodclots in rats by Jin R1, Zhu X1, Li G(PubMed)
(5) How to prevent clots in the legs and lungs. A blockage outside the heart can be just as dangerous as a heart attack.[No authors listed](PubMed)
(6) Deep venous thrombosis in a patient presenting with severe left inguinal and hip pain: a case report by Fidan F1, Alkan BM, Tosun A, Ardçoğlu Ö(PubMed)
(7) Building a protocol to guide mobility in the ICU by Dammeyer J1, Dickinson S, Packard D, Baldwin N, Ricklemann C(PubMed)
(8) NF-κB TRANSCRIPTION FACTOR p50 CRITICALLY REGULATES TISSUE FACTOR IN DEEP VEIN THROMBOSIS by Yi-Dan Li1,#, Bu-Qing Ye1,#, Sheng-Xi Zheng1 , Jin-Tao Wang1 , Jian-Guo Wang2 , Ming Chen1 , Ji-Guo Liu1 , Xin-Hui Pei1,3, Li-Jing Wang4 , Zhi-Xin Lin3 , Kalpna Gupta5 , Nigel Mackman2 , Arne Slungaard5 , Nigel S. Key2 , Jian-Guo Geng(JBC (Papers in Press)
(9) Diseases associated with thrombosis by de Laforcade A(PubMed)

Friday, October 19, 2018

The Pungent Spice That Crucifies Breast Cancer Cells, Scientists Reveal

The finding of whole food medication by scientists all over the world to replace the single ingredient of a Western medicine for treatment of breast cancer with little or no side effect has been difficult due to no commercial benefits and patent right to producers.

Breast cancer is a medical and chronic condition characterized by irregular cells growth in the breast tissue.

In most cases, breast cancer (malignant breast neoplasm) starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

There are also rare cases that breast cancer starts in other areas of the breast.

According to statistic, in 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of women is 1/8.

Depending to the stage of cancer, women in the very early stage (increased risk of breast cancer) may only experience rusting at the nipple, bloody nipple drainage, a retracted, flattened nipple, particularly in those symptoms that do not go away in 2 weeks.


In the early stage of breast cancer, the tumor is smaller than the approximate size of a peanut (2 centimeters or smaller) and localized.

The survival rate of women diagnosed at this early stage is 100%.


In the breast cancer stage, according to the American Cancer Society, any of the following unusual changes in the breast can be a symptom of breast cancer such as swelling of all or part of the breast, skin irritation or dimpling. breast pain, nipple pain or the nipple turning inward. redness, scaliness, or thickening of the nipple or breast skin.

Therefore, regardless of breast cancer risk, self-examination is one of the best method to detect early breast cancer. All woman should be herself looking at and feeling each breast for possible lumps, distortions or swelling monthly,

Some researchers suggested that women with alternated genes and family history of breast cancers might be required to have their mammogram taken annually.


Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.

The food or herb has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.

According to the study, administration of fresh Garlic Extract only exerted a significant effect in the inhibited colon and gastric cancer, but also stimulated cancer cell cycle arrest and alternated the morphology of MCF7 breast cancer cells.

In MCF7 human breast cancer cells, garlic constituent diallyl trisulfide have highly effective antitumor effects by suppressing viability of cultured MCF-7 and MCF-12a cells, through decreased the percent of cells in G(2)/M and induced apoptotic cell death.

According to the study by 201 South University Street, diallyl trisulfide, inhibited the expression of MDA-MB-231 and MCF-7 breast cancer cells, regardless of the state of estrogen in the tumors.

In a total of in 285 women (aged 25-65 years old) newly diagnosed with histopathologically confirmed breast cancer, dietary Allium Vegetables has a negative association between the consumption of raw onion and risk of breast cancer.


Dr. Roy N., the lead author at the Kerala Agricultural University, said, "Docking studies and ADMET evaluation revealed twelve compounds (isolated from garlic) to be active against the targets(breast cancer cell lines). All the compounds displayed highly negative dock scores which indicated good interactions".

These results suggested that the effectiveness of garlic in reduced risk and treatment of breast cancer is probably due to the existence of many phytochemicals found in the herb.

Adding garlic intake to your daily diet can ameliorate the risk of breast cancer substantially.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Fresh Garlic Extract Induces Growth Arrest and Morphological Differentiation of MCF7 Breast Cancer Cells by Modem S1, Dicarlo SE, Reddy TR. (PubMed)
(2) Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells by Malki A1, El-Saadani M, Sultan AS.(PubMed)
(3) Diallyl trisulfide, a chemopreventive agent from Allium vegetables, inhibits alpha-secretases in breast cancer cells by Kiesel VA1, Stan SD2. (PubMed)

Thursday, October 18, 2018

A Common and Kitchen Spice that Curbs Diabetes Naturally

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

Type 1 diabetes is a congenital condition caused by the die-off of pancreas cells which are responsible for producing insulin, a hormone with a function to control the level of blood glucose.

A regular injection of insulin or insulin therapy is required daily in a patient who was born with the disease.

In contrast to type II diabetes, types 1 diabetes are not associated with dietary intake or unhealthy lifestyle that can cause an increase in glucose levels in the blood.

According to Diabetes Canada, patients with type 1 diabetes should aware of the number of insulin injections that are needed per day; the timing of insulin injections and the dose of insulin that is needed with each injection

The cause of type 1 diabetes is debatable, but some researchers found that most patients with type 1 diabetes are linked to abnormal body’s immune system overreaction to the cells that make insulin.

On the other hand, type 2 diabetes is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol due to unhealthy dietary and lifestyle selections.

In some cases, the diseases are also caused by allergic reactions of cells in the immune system.

If you experience some of the physical symptoms of frequent urination, excessive thirst, unexplained weight loss, nonrefractive visual impairment, and appetite problems, together with gastrointestinal symptoms such as stomach pain, heartburn, diarrhea, constipation, nausea and vomiting and mental symptoms of depression, emotion stress, sleeping difficulties,..... and suicidal ideation, you may have type 2 diabetes. Please check with your doctor as soon as possible(4).

According to the 2011 statistic from National Diabetes Information Clearinghouse (NDIC), among U.S. residents ages 65 years and older, 10.9 million, or 26.9 percent, have diabetes in 2010.

About 215,000 people younger than 20 years had diabetes—type 1 or type 2—in the United States in 2010.

And approximately, 1.9 million people ages 20 years or older were newly diagnosed with diabetes in 2010 in the United States.

For my years of practice and research, I do believe that intake of 1/4 tablespoon of Vietnamese cinnamon powder in the morning and evening have significant effects in keeping blood sugar in check.

In prediabetes with the morning reading of 6.9 mmol/L of a lady whom I know for 10 years, intake of the volume of cinnamon suggested above has managed to maintain her's the morning blood glucose at 5.3 mmol/L since.

Cinnamon, a kitchen spice used in many cultures, may have gained many believers, including medical professions because of its antidiabetic effect, through regulating the blood glucose levels in healthy and diabetic subjects.

According to herbalists, intake of 1/4 tsp. in the morning and evening may reduce the blood sugar significantly with little or no adverse side effects.

The herb has been used in herbal and traditional medicine as anti-fungal and bacteria activities and improves reproductive organ, prevents flatulence and intestinal cramping, treats indigestion, diarrhea, bad breath, headache, migraine, etc.(1).

In a total of 66 patients with type 2 diabetes study conducted by Xuhui District Central Hospital, researchers found that oral administration of cinnamon reduced significantly of blood triglyceride levels even in the low-dose group, after 3 months. (2).

Some researchers suggested that cinnamon extract improved fasting blood glucose levels and glucose tolerance without altering the insulin secretion may be attributed to its effects in lowering triglyceride and increasing liver glycogen content and improving insulin action in liver tissues(3).

Dr. Kim SH and Dr. Choung SY. told PubMed that “the effect of cinnamon significantly increases insulin sensitivity, reduces serum, and hepatic lipids, and improves hyperglycemia and hyperlipidemia possibly by regulating the PPAR-medicated glucose and lipid metabolism”(4).

Peroxisome proliferator-activated receptors (PPARs) including PPARα, PPARγ, and PPARβ/δ are receptors that reduce triglyceride level and regulate energy homeostasis.
In support of the above, chromium(Cr) and polyphenols found in cinnamon(Cinnamomum cassia) displayed a significant improvement of glucose, insulin, cholesterol, and HbA1c in patients with type 2 diabetes, according to a double-blind placebo-controlled study(7).

Unfortunately, according to the Western University of Health Sciences, even though consumption of cinnamon is associated with a statistically significant decrease in levels of fasting plasma glucose, but high degree of heterogeneity including quality and content may limit the ability to apply these results to patient care, due to the unclear preferred dose and duration of therapy(5).

Moreover, a randomized clinical trial in which 70 Patients with type II diabetes were assigned randomly into two groups (35 in cinnamon and 35 in placebo group) for the testing of the effect of cinnamon on the glucose level in blood, at the end of the experiment researchers found that there is an insignificant effect of using cinnamon on glucose level of diabetic patients and the herb should not be recommended to patients with type II diabetes depending on further studies(6).

Taken altogether, although there are some discrepancies involving cinnamon efficacy, I do believe that cinnamon in low dose is effective to control and manage the level of blood glucose in the patient with diabetes without altering the insulin level.

However, according to Dr. Georgakopoulou EA(7), oral intake of cinnamon may cause Stomatitis, and burning sensation in the mouth if it is taken in large amounts.

The traditional Chinese medicine also indicated that overdoses of cinnamon can be toxic and damage the liver(1).

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) @Popular Herbs -Cinnamon
(2) Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes by Lu T, Sheng H, Wu J, Cheng Y, Zhu J, Chen Y. (PubMed)
(3) Cinnamon extract improves insulin sensitivity in the brain and lowers liver fat in mouse models of obesity by Sartorius T1, Peter A2, Schulz N3, Drescher A2, Bergheim I4, Machann J5, Schick F6, Siegel-Axel D2, Schürmann A3, Weigert C1, Häring HU1, Hennige AM(PubMed)
(4) Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice by Kim SH1, Choung SY. (PubMed)
(5) Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis by Allen RW1, Schwartzman E, Baker WL, Coleman CI, Phung OJ. (PubMed)
(6) The Effect of Cinnamon on Glucose of Type II Diabetes Patients by Hasanzade F1, Toliat M2, Emami SA3, Emamimoghaadam Z(PubMed)
(7) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA. (PubMed)
(8) Diabetes – The Symptoms by Kyle J. Norton

Wednesday, October 17, 2018

A Miracle Bean Which Is Better Than Probiotics and Prebiotics In the Optimization of Bowel Health

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has played an important role in human history over many centuries.

The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Bowel disease is a result of digestive dysfunction. People experience some minor gastrointestinal problems one in a while.

In some cases, digestive dysfunction can cause stomach discomforts such as bloated and sluggish. However, in serious cases, the digestive problem may lead to the development of irritable bowel syndrome, constipation, diarrhea, stomach-ache, nausea.

According to statistic, Irritable bowel syndrome (IBS) is the most common form of functional bowel syndrome, affecting approximately, 10–15% worldwide population.

In the US, about 2.4 and 3.5 million people suffer the syndrome annually.

Some researchers suggested that bowel disease may be associated with an imbalance of ratio of gut microbiota.

In other words, bowel disorder occurs when the bad bacteria have overgrowth in compared to the good one.

Overgrowth of C. difficile is associated to diarrhea. Long-term of unhealthy microbiota can lead to inflammatory bowel disease, inducing obesity, diabetes, and Cardiovascular Disease(5).

Dr. Miele L, the lead author said, "Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes" and "Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders".


According to general belief, in taking probiotic may be considered as a healthy choice in improved gut health. However, according to recent study, "While evidence of the preventive and therapeutic effects of probiotic strains on diarrhoeal illness and other intestinal conditions is promising, the exact mechanisms of the beneficial effects are not fully understood" and "Recent studies have raised the question of whether non-viable probiotic strains can confer health benefits on the host by influencing the immune system".

Some health care professionals in services of patients with bladder and bowel diseases suggested that eating a balanced diet, drink enough fluids, limit the amount of alcohol you consume, chew your food well,...... and don’t miss meals may have potential effect in the contribution of a healthy bowel(7).

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

With Nutrients of
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Vitamin E
14. Vitamin K
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc

People who follow a typical American diet may express a certain problem in bowel movement, as a result of consuming high saturated fat, salt, sugar....... and less of fiber.

According to the University of Tasmania, diet not only affects food choice, satiety but also have a profound influence on bowel health.

As 15 participants.who participated in the study showed the trend of eating more processed snack foods (high energy, low fiber) after ceasing chickpea consumption(1).

In 27 free-living adults followed two randomized, crossover dietary interventions each of five weeks duration, Dr. Pittaway JK and research team said,"... a significant decrease in serum TC and LDL-C during the chickpea diet compared to the equivalent fiber wheat diet was partly due to unintentional changes in macronutrient intake occurring because of chickpea ingestion"(2).

The effect of chickpea in the promotion of bowel health may be the result of a high amount of dietary fiber found in the legume.

In the study of the effectiveness of probiotics, prebiotics, and dietary fiber in the treatment of FGD in the pediatric population, researchers suggested that administration of a fiber supplement is more effective than placebo for the treatment of childhood constipation(3).

In fact, fiber undergone partial or total fermentation after conscription in the distal small bowel and colon can lead to the production of short-chain fatty acids and gas, thereby affecting gastrointestinal function and sensation, the University of Michigan Health System, insisted(4).

And high-fiber diet showed to improve bowel function and health-related quality of life in patients with Crohn disease(8), according to the study of 2-group individuals diagnosed with the disease.

The results suggested that consuming foods with fiber score a significant effect in improved health-related quality of life and gastrointestinal function in compared to the same foods that without.


Taking all together, people who eat some portions of chickpea every day may improve the bowel health, regardless of types of diet.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources

(1) Chickpea supplementation in an Australian diet affects food choice, satiety and bowel health by Murty CM1, Pittaway JK, Ball MJ. (PubMed)
(2) Effects of a controlled diet supplemented with chickpeas on serum lipids, glucose tolerance, satiety and bowel function by Pittaway JK1, Ahuja KD, Robertson IK, Ball MJ. (PubMed)
(3) Probiotics, prebiotics, and dietary fiber in the management of functional gastrointestinal disorders by Horvath A1, Szajewska H.(PubMed)
(4) Fiber and functional gastrointestinal disorders by Eswaran S1, Muir J, Chey WD. (PubMed)
(5) Impact of Gut Microbiota on Obesity, Diabetes, and Cardiovascular Disease Risk by Miele L1,2, Giorgio V3, Alberelli MA4, De Candia E5, Gasbarrini A6, Grieco A(PubMed)
(6) Intestinal microbiota, diet, and health by Power SE1, O'Toole PW1, Stanton C2, Ross RP2, Fitzgerald GF(PubMed)
(7) Maintaining A Healthy Bowel(B&B)
(8) A high-fiber diet may improve bowel function and health-related quality of life in patients with Crohn disease by Brotherton CS1, Taylor AG, Bourguignon C, Anderson JG(PubMed)

Tuesday, October 16, 2018

Cayenne, The Spice That Blocks Airway Inflammation, Scientists Reveal



Scientists in numbers of institute suggested that cayenne, a kitchen spice may process a significant effect in inhibited airway inflammation, an important component of asthma, chronic obstructive pulmonary disease (COPD), and the various cough syndromes.

Conventional medicine has synthesized the effect of many of herbal plants' secondary metabolites, since the discovery of penicillin, the first antibiotic extracted from a very primitive plant, the fungus Penicillium, in 1928, used for the treatment of infection.

In years, herbalist is suspicious that these plants must contain some substances used together for healing purposes, without knowing the existence of every single ingredient.

Today, under microscopes of new technology, scientists discovered that effectiveness of herbal plants in the treatment of conditions and diseases are attributed to their's secondary metabolites.

Secondary metabolites are organic compounds, according to Massachusetts Institute of Technology that serve(7)
* As competitive weapons used against other bacteria, fungi, amoebae, plants, insects, and large animals.

* As metal transporting agents.

* As agents of symbiosis between microbes and plants, nematodes, insects, and higher animals.

* As sexual hormones; and

* As differentiation effectors.

for the survival of the plants producing them.

Following the herbalist food step and used herbal medicine as a fundamental source, conventional medicine has discovered numbers of single-ingredient medication, including quinine (from cinchona bark), and morphine (from the opium poppy)......

According to the Dr. Stanley F. Malamed, the lead author in the study of causative factors for acute asthma suggestion, "(In acute airway inflammation) Inflammation may occur as a result of either immunologic or nonimmunologic airway insults, which produce airway edema and cause the immigration of inflammatory cells into the lumen through the epithelium "(5)

Chronic airway inflammation can lead to chronic obstructive pulmonary disease (COPD), a progressive syndrome caused by expiratory airflow limitation as a result of airway remodeling, including an increase in airway smooth muscle (hyperplasia and hypertrophy),......

More importantly, the longer duration of airway inflammation may lower the lung function in induction of the worse of the bronchial hyperresponsiveness and symptoms(6)

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belongings to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions.

The herb or food has been used in traditional medicine to increase metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, ......., particularly, in treatment of inflammation caused by invasion of microbial organisms and allergens.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases, including inflammation.

Red pepper (Capsicum baccatum) extracts, according to the study by the Federal University of Rio Grande do Sul (UFRGS), exerted its anti-inflammatory properties through in inhibiting the neutrophil migration induced by carrageenan (Cg).

In animal study, the ethanolic and butanol extracts (200mg/kg, p.o.) presented a significant anti-inflammatory activity through their antioxidant phenolic and flavonoid compounds against oxidative and inflammation-related pathological processes, including airway inflammation.

β-Defensin, members of the antimicrobial peptide found in cayenne inhibited the expression of the mRNA of anti-inflammatory cytokine during the bacterial invasion, through stimulating immunomodulatory effects.

Other research suggested that anti-inflammatory effect induced by red pepper may be by inhibition of pro-inflammatory cytokine production at the inflammatory sites, such as upper airway.

Regular intake of Cayenne pepper can improve immune system against microbial infection and reduced risk of airway inflammation but overdose is found to induce toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Red Pepper (Capsicum baccatum) Extracts Present Anti-Inflammatory Effects In Vivo and Inhibit the Production of TNF-α and NO In Vitro by Allemand A1,2, Leonardi BF1, Zimmer AR1, Moreno S3, Romão PR2, Gosmann G1. (PubMed)
(2) Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation by Spiller F1, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR. (PubMed)
(3) Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach by Zimmer AR1, Leonardi B, Miron D, Schapoval E, Oliveira JR, Gosmann G.(PubMed)
(4) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2. (PubMed)
(5) Learn more about Airway Inflammation(Science Direct)
(6) Why Does Airway Inflammation Persist? Is It Failure to Treat Early? by SØREN PEDERSEN(ATS Journals)
(7) The natural functions of secondary metabolites by Demain AL1, Fang A(PubMed)

Monday, October 15, 2018

Detoxification: How To Detox And Nourish Your Liver For Optimal Health, Citation Provided By PubMed


The western diet contains high saturated fat, trans fat, and other harmful substances such as sugar, caffeine, pesticides, addictive substances, and less in fruits and vegetables.

These types of harmful substances are toxic and induced a shift in microbiota composition in enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation(10).

Some researchers suggested that the escalating consumption of fat and sugar in Western countries are associated parallelly in an increased incidence of cardiovascular disease during the latter 20th century(10).
Also, according to the report in The American Journal of Pathology and studied mice module, Western diet altered the bile acid profile and elevated liver inflammation(12) as well as promoted other Western-pattern diet-related diseases, including nonalcoholic fatty liver disease, metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis(11).

Our body's detoxified functions try to get rid of them every day. When they fail, the toxins can cause a disruption of hormone production, damage to our body's detoxification organs and the immune system, leading to hormone imbalance and the development of chronic ailments.

The Natural Remedies Detox And Nourish Your Liver include
1. Milk thistle

Milk thistle, a flowering plant of the daisy family have been traditionally claimed in treating chronic liver disease.

The herbal medicine contains silymarin with impressive functions in protected liver function and expelled liver toxins.

In a study to compared Cirsium japonicum DC's flavonoids, liver protection against liver toxicity using carbon tetrachloride (CCl4) with silymarin as a positive control, researchers after taking into account of other co and founders found that silymarin exerts a clear hepatoprotective effects similar to those of Cirsium japonicum DC's flavonoids against toxins caused by injection of carbon tetrachloride (CCl4)(1)

Dr. Ma Q, the lead scientist said, "The results indicated that the pretreatment with C. japonicum flavonoids could significantly reverse CCl4-induced L02 cell viability decrease similarly to silymarin".

Silymarin is a mixture of flavonoids from Silybum marianum(milk thistle), a traditional European food plant with clear hepatoprotective effects.

2. Licorice
Licorice is a legume plant and native southern Europe and parts of Asia.

The herbal medicine contains a bioactive compound glycyrrhizin, which demonstrated a significant liver protective effect against liver toxins through suppression of hepatic stellate cell inactivation of liver fibrosis in some studies(3).

According to the seven-day intraperitoneal administration of glycyrrhizin (400 mg/kg/day) to 2- to 3-month-old male C57BL/6N mice (mean weight 27 g) against acetaminophen-induced liver damage observed by activity of alanine transaminase and aspartate aminotransferase, application of glycyrrhizin significantly reversed the increased levels of long-chain acylcarnitines in induction of liver damage and toxicity(2).

Further differentiation of this metabolomic assay, suggested that glycyrrhizin exert a significant protective effect against acetaminophen-induced liver damage induced by toxic acetaminophen through reversing fatty acid metabolism(2).

3. Tabebuia heptaphylla
Tabebuia heptaphylla is the botanical name of Pau d'Arco
The herbal plant contains alkaloids, flavonoids, sulfur, and essential oils which have a strong effect in enhanced helping to support the immune activity(4).

The herb displayed a strong hepaprotective effect against liver damage and toxicity, probably due to major bioactive compound flavonoids(4).

4. Stilingia root

Stilinga root not only strengthens the immune cells but also prevent and treating food allergies and eczema by stimulating the removal of toxins accumulation in the liver caused by long-term eating of preservatives, canned foods, fast foods, and excessive alcohol drinking.

According to the Scovill's compound syrup of sarsaparilla and stillingia, or, Blood and liver syrup for the cure of scrofula and all diseases of the blood and liver by A.L. Scovill & Co, stillingia root processes a strong hepaprotective effect against liver disease and liver toxins.

5. Prickly ash

Prickly ash is also known as toothache tree. It has been used traditionally as a digestive aid and to strengthen the nervous system. Prickly ash is considered as a tonic and stimulant herb for the liver and gallbladder.

As a holistic cleanser, Prickly ash eliminates toxins, including liver toxicity(5).


6. St. John Wort

St. John wort is also known as Tipton weed or Klamath weed.

The herb has been used popularly for its effect in ameliorated depression.

Major bioactive flavonoids and 3-O-coumaroylquinic acid process anti-inflammation and antioxidant effects in stimulating the immune system in fighting allergies and in protected liver against toxins(6).
.
Dr. Aydin A and colleagues in the study of the effects of St. John wort on hepatic ischemia suggested that application of H. perforatum on rat model exerts a strong liver protection against hepatic ischemia locally and systemically(6),

Its chromone glycosides also showed moderate hepatoprotective activity with EC(50) values of 160.2 microM and 217.7 microM, respectively, against tacrine-induced cytotoxicity in HepG2 cells(7).




7. Fennel
Fennel contains anethole, polymers and essential oil with function in improved liver and pancreas in the metabolism of fats and sugars.

The herbal medicine also has a strong effect in dissolved fat deposits of the body and restored damaged liver cells that cause jaundice, hepatitis and other liver disorders(8)(9).


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Hepatoprotective effect of flavonoids from Cirsium japonicum DC on hepatotoxicity in comparison with silymarin by Ma Q1, Wang LH, Jiang JG(PubMed)
(2) Targeted metabolomic study indicating glycyrrhizin’s protection against acetaminophen-induced liver damage through reversing fatty acid metabolism by Yu J, Jiang YS, Jiang Y, Peng YF, Sun Z, Dai XN, Cao QT, Sun YM, Han JC, Gao YJ(PubMed)
(3) Protective mechanisms of medicinal plants targeting hepatic stellate cell activation and extracellular matrix deposition in liver fibrosis by Florent Duval, Jorge E Moreno-Cuevas, María Teresa González-Garza,Carlos Rodríguez-Montalvo, and Delia Elva Cruz-Vega(PMC)
(4) Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids by Chin-Lin Hsu*†, Gow-Chin Yen‡§1, in The Enzymes, 2014(Science Direct)
(5) Facts and benefits of Prickly Ash(Health Benefits Times)
(6) The effects of Hypericum perforatum on hepatic ischemia-reperfusion injury in rats by Aydin A, Sakrak O, Yilmaz TU, Kerem M(PubMed)
(7) Chromone glycosides and hepatoprotective constituents of Hypericum erectum by An RB1, Jeong GS, Beom JS, Sohn DH, Kim YC(PubMed)
(8) Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice by Warnet JM1, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR(PubMed)
(9) Protective mechanism of anethole on hepatic ischemia/reperfusion injury in mice by Cho HI1, Kim KM, Kwak JH, Lee SK, Lee SM(PubMed)
(10)Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation by Agus A1, Denizot J1, Thévenot J1,2, Martinez-Medina M1, Massier S1, Sauvanet P1,3, Bernalier-Donadille A4, Denis S2, Hofman P5, Bonnet R1,6, Billard E1,7, Barnich N(PubMed)
(11) Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis by Schierwagen R1, Maybüchen L1, Zimmer S2, Hittatiya K3, Bäck C4, Klein S1, Uschner FE1, Reul W1, Boor P5, Nickenig G2, Strassburg CP1, Trautwein C4, Plat J6, Lütjohann D7, Sauerbruch T1, Tacke F4, Trebicka J(PubMed)
(12) Western Diet Consumption May Increase Risk of Chronic Liver Inflammation in Men by All India | NDTV Food Desk | Updated: July 12, 2017, 16:05 IST(NDTV)