Herbal Alfalfa,The Anti-inflammatory Diseases Natural Whole Food and Plant

The efficacy of botany in the use of plants for treatment and cure diseases with little or no side effects have drawn interest in today conscientious scientists, since the discovery of aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)...

However, the development of synthetic single medicine for treating diseases is not beneficial to patients but profits to the big pharmaceutical companies symptoms.

The use of conventional medicine for the treatment of one disease is found to induce serious side effects in the short term and serious complications in the long-term.

Examples
* Intake of aspirin may facilitate symptoms of black, bloody, or tarry stools; coughing up blood, severe nausea, vomiting,........ and stomach pain. Long-term use of the medicine can cause stroke as a result of burst blood vessels,.... and gastrointestinal bleeding.

* Administration of quinine can induce serious symptoms of fever, chills, confusion, weakness, sweating; severe vomiting, stomach pain,.... and diarrhea chest pain. And long-term intake can induce trouble breathing, severe dizziness, fainting, fast or pounding heartbeats,.... and problems with vision or hearing.

Inflammation is a natural process of immune reaction that protest our body against infection and injury. Overexpression of inflammatory substances produced by the immune system may cause the localized physical condition of reddened, swollen, hot, and often painful. However, in some cases, over the presence of pro-inflammatory cytokines can induce cytotoxicity that damages healthy cells and tissue.

According to the free dictionary by Farlex(4), there are 3 major components that make up the state of acute inflammation, including
* Changes in the caliber of blood vessels and the rate of blood flow through them (hemodynamic changes)
* Increased capillary permeability, and
* Leukocytic exudation.

And chronic inflammation may be a slow onset but it is characterized by persistent inflammation and lack of clear resolution as the infectious tissues and cells are no longer able to overcome the effects caused by the injuring agents.

Chronic inflammation can eventually cause several diseases and conditions, including some cancers, autoimmune diseases,....... and rheumatoid arthritis.


Alfalfa, a botany plant may be used to modulate immune response for treatment of acute inflammation and diseases associated with chronic inflammation, some scientists suggested.

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding.

The herbal plant has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhanced digestive system, bleeding disorder, kidney, and urinary tract infection, etc.

North American aboriginals have used Alfalfa seed as food in making bread and mush.

According to studies, alfalfa expressed significant anti-inflammatory effect through the inhibiting production of pro-inflammatory cytokines during injury, foreign invasion, and free radical domino's action, etc....

The University of Maryland study of novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem, suggested that the phytochemicals isolated from alfalfa exert significant anti-inflammatory effect against mRNA expressions of the pro-inflammatory cytokine genes, especially for IL-1β antibody(1).

IL-1β is a pro-inflammatory cytokine that used the major source of macrophages in response to the early stage of inflammation.


Chronic inflammatory expression of human IL-1β is associated with gastric inflammation and tumorigenesis in stomachs of studies mice.

The chloroform extract of alfalfa aerial part also inhibited the function of lipopolysaccharide (LPS) of Gram-negative bacteria in stimulated immune responses in induced inflammation and suppressed LPS-mediated activation of the extracellular signal-regulated the proinflammatory and prothrombotic responses of nuclear factor kappa-B pathway(2).

Dr. Toby Lawrence, in the evaluation of "The Nuclear Factor NF-κB Pathway in Inflammation" said, "The nuclear factor NF-κB pathway has long been considered a prototypical proinflammatory signaling pathway, largely based on the role of NF-κB in the expression of proinflammatory genes including cytokines, chemokines, and adhesion molecules" and " NF-κB has long been considered the “holy grail” as a target for new anti-inflammatory drugs"(6).

The cinnamic acid derivatives and fatty acids active constituents of the extract were also effective in ameliorated inflammation and immune response through inhibition of nitric oxide (NO), tumor necrosis factor (TNF-α), and prostaglandin E2 (PGE2) involved in the development of inflammatory diseases(3).

Nitric oxide (NO), plays a duo role in the pathogenesis of inflammation as anti-inflammatory cytokine under normal physiological conditions. However, the molecule also acts as a pro-inflammatory mediator in abnormal situations.

Tumor necrosis factor (TNF-α), a key regulator of the inflammatory response, plays an important role in the regulation of cellular responses, which include cell death, survival, differentiation, proliferation, and migration by stimulating a change of vascular endothelial cells in expression of pro-inflammation.


Prostaglandin E2 (PGE2) may function in both the promotion and resolution of inflammation.

However, under the abnormal condition such as persistent tissue damage, the hormone may contribute to the up-regulation of the pro-inflammatory cytokines.


Taking together, alfalfa no doubt has processed anti-inflammatory effects through inhibited free radicals, proinflammatory cytokines and hormone that involve the development of inflammatory and autoimmune diseases.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Structural, thermal, and anti-inflammatory properties of a novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem by Chen L, Liu J, Zhang Y, Dai B, An Y, Yu LL1. (PubMed)
(2) Chloroform extract of alfalfa (Medicago sativa) inhibits lipopolysaccharide-induced inflammation by downregulating ERK/NF-κB signaling and cytokine production by Choi KC1, Hwang JM, Bang SJ, Kim BT, Kim DH, Chae M, Lee SA, Choi GJ, Kim DH, Lee JC. (PubMed)
(3) Anti-Inflammatory Activities of Cinnamomum cassiaConstituents In Vitro and In Viv by Jung-Chun Liao,1 Jeng-Shyan Deng,2 Chuan-Sung Chiu,3,4. (HindaWi)
(4) Acute inflammation, the free dictionary by Farlex
(5) IL-1β by Science Direct
(6) The Nuclear Factor NF-κB Pathway in Inflammation by Toby Lawrence. (PMC)

The Anti Fungal Infection Whole Food

The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefits and patent right to producers.

Fungal infection is a common disease caused by overgrowth of fungus.
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.

People with a weakened immune system such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.


Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes include jock itch, athlete's foot,..... and ringworm.

Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,...... and burning sensation.

In women, signs of yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........ and unusual vaginal discharge.


In men, signs of yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.

If you experience some of the signs and symptoms indicated above, you may be infected by yeast. Please check with your doctor as soon as possible.

If you are given topical creams, oral medicine or antifungal injection, please make sure you understand the common and serious of side effects before applying.

Garbanzo bean(Chickpea) and its bioactive phytochemicals may be considered as antifungal function food in prevention and treatment of overgrowth of fungal species, some scientists suggested.

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae.

It is one of the earliest cultivated vegetables in mankind, native to the Middle East.

The joint study lead by the ICAR-Indian Agricultural Research Institute suggested chickpea with abundant bioactive compounds may be used along with the relevant antioxidant capacities as antifungal whole food, through the expression of defense-related enzymes like l-phenylalanine ammonia lyase, peroxidase and polyphenol oxidase(1).
Phenylalanine ammonia lyase is an enzyme that converts ammonia and trans-cinnamic acid involved proper function of the neuron(7).



Peroxidase and polyphenol oxidase are antioxidants that inhibit overexpression of free radicals.

According to the study by the All India Institute of Medical Sciences, in the emergence of epidemic fungal pathogenic resistance to current antifungal drugs, C-25 found in Garbanzo beans(Chickpea) not only processes an effective antimycotic but also antiproliferative agent against human oral cancer cells(2).

In support to the above, chickpea is found to exhibit inhibitory activity against Aspergillus flavus in a study conducted by the South China Normal University(3).


Taken altogether garbanzo bean(chickpea) may be considered a functional food for the prevention and treatment of fungal infection. People with a high risk of fungal infection may want to add a portion garbanzo bean(chickpea) which processes abundant bioactive compounds into a daily diet for preventive measure.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Development of Mesorhizobium ciceri-Based Biofilms and Analyses of Their Antifungal and Plant Growth Promoting Activity in Chickpea Challenged by Fusarium Wilt. by Das K1, Rajawat MVS1, Saxena AK1,2, Prasanna R1.(PubMed)
(2) Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens by Kumar S1, Kapoor V2, Gill K1, Singh K1, Xess I3, Das SN2, Dey S1(PubMed)
(3) Some 2S albumin from peanut seeds exhibits inhibitory activity against Aspergillus flavus by Duan XH1, Jiang R, Wen YJ, Bin JH.(PubMed)
(4) Antibacterial and antifungal activity of cicerfuran and related 2-arylbenzofurans and stilbenes by Aslam SN1, Stevenson PC, Kokubun T, Hall DR.(PubMed)
(5) Cicerarin, a novel antifungal peptide from the green chickpea byChu KT1, Liu KH, Ng TB.(PubMed)
(6) Cicerin and arietin, novel chickpea peptides with different antifungal potencies by Ye XY1, Ng TB, Rao PF.(PubMed)
(7) Effects of cinnamic acid on memory deficits and brain oxidative stress in streptozotocin-induced diabetic mice by Hemmati AA1, Alboghobeish S2, Ahangarpour A(PubMed).

The Root Veggie and Its Bio Active Compounds That Prevent Stroke

Carrots may have a profound and positive effect in reduced risk of stroke, some scientists suggested.

Stroke is a medical condition caused by reduced blood flow to the brain resulting in cell death due to the blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).

There is a general belief that stroke is an accumulation over a long period of unhealthy diet with red meat and processed meats in induction of artery-clogging.

Some researchers suggested that increased intake of fruits and vegetables such as carrot accompanied with good fats such as salmon, tuna, and mackerel may have a substantial effect in reduced inflammation in the arteries, improved blood flow and decreased the chance of blood clots.

Sadly, stroke is one of the most common causes of death worldwide.

In the US, according to statistic, approximately 800,000 people suffer a stroke in which 600,000 of these are first attacks, and 185,000 are recurrent attacks. Nearly three-quarters of all strokes occur in people over the age of 65.


Carrot, a root vegetable with an orange color is a sub species of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.

In the review of literature published to understand more of the role of carotenoids as antioxidants in lowering stroke risk based on observational studies, researchers at the Isfahan University of Medical Sciences conducted a search with some important keywords, including (Carotenoids [MeSH] OR Carotenes [tiab] OR Carotene [tiab] OR "lycopene [Supplementary Concept]" [MeSH] OR lycopene [tiab] OR beta-Carotene [tiab]) AND (stroke [MeSH] OR stroke [tiab] OR "Cerebrovascular Accident" [tiab] OR "Cerebrovascular Apoplexy" [tiab] OR "Brain Vascular Accident" [tiab] OR "Cerebrovascular Stroke" [tiab]) AND ("oxidative stress" [MeSH] OR "oxidative stress"[tiab]).

The results of the searching of papers published between 2000 and 2017 suggested that

* High dietary intake of six main carotenoids (i.e., lycopene, <- and®-carotene, lutein, zeaxanthin, and astaxanthin) was associated with reduced risk of stroke due to their benefits in reduced overexpression of reactive oxygen species.

* Beyond the antioxidant activities in preventing free radical in the induction of chain reaction, other properties and mechanisms in ameliorated risk of stroke were not identified in studies sanctified the guideline and criteria.

These results suggested that dietary intake of six major carotenoids may be considered as stroke prevention and stroke mortality reduction.

Further in differentiation the benefits of lycopene a bioactive member in carotenoids, researchers found that intake of food containing a high amount of lycopene demonstrates a substantially reduced risk of stroke in compared to nontakers.

According to the assessment of pooled analysis of seven prospective studies, with 116,127 participants and 1,989 cases, frequent consumption of lycopene decreased stroke risk by 19.3%, after adjusting for confounding factors.


In gender and geographic analysis, researchers also stated that lycopene exerts a strong impact in preventing the onset of stroke, particularly in European and male gender.

Dr. the lead scientist said, " Duration of follow-up had no effect on the final results. There was no evidence of publication bias" and " Lycopene, especially circulating lycopene, is negatively associated with stroke risk".

Additionally, in the examine the hypothesis whether low serum levels of lycopene are associated with increased risk of acute coronary events and stroke in middle-aged men previously free of CHD and stroke, researchers launched an investigation of 725 men aged 46-64 years examined in 1991-3 in the Kuopio Ischaemic Heart Disease Risk Factor Study.

By December 1997, out of 725 patients, 41 men were found to have either a fatal or a non-fatal acute coronary event or a stroke.

According to the observation of a Cox' proportional hazard's model and after adjusting to examination years, age, systolic blood pressure and three nutritional factors (serum folate, beta-carotene, and plasma vitamin C), researchers found that all 41 men are in the lowest quarter of serum lycopene levels.

These results once again suggested that daily intake of lycopene-rich foods to increase the circulating lycopene plays an essential role in the prevented risk of atherosclerotic vascular events in middle-aged men previously free of CHD and stroke.

Truly, patients with lower levels of serum lycopene were found to had a 3.3-fold risk of acute coronary events or stroke in compared with the others.

Taken together, carrot with a high amount of bioactive carotenoids, especially lycopene may be considered as a functional food in reduced the prevalent risk of stroke.

People who are at the higher quarter of stroke risk may want to add a portion of carrot into their daily diet for preventive measure.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review by Bahonar A1, Saadatnia M1, Khorvash F1, Maracy M2, Khosravi A(PubMed)
(2) Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies by Li X1, Xu J2.(PubMed)
(3) Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study by Rissanen TH1, Voutilainen S, Nyyssönen K, Lakka TA, Sivenius J, Salonen R, Kaplan GA, Salonen JT.(PubMed)
(4) Healthy eating and stroke(Stroke Foundation)
(5) Stroke Statistics by The Internet Stroke center

Garlic, The Herb and Roots Spice That Gobbles Up Arterial Plaques Before They Can Cause Atherosclerosis

A recent study suggested that patients with atherosclerosis may be benefits from adding aged garlic extract with supplement into their diet.

Atherosclerosis is a disease with plaque builds up inside the arteries, affecting the levels of oxygen in the blood as well as increasing risks of heart attacks, strokes, and peripheral vascular disease.

Atherosclerosis is a slow, progressive disease that may begin as early as childhood, caused by damage of the inner lining of the artery. However, the actual causes of the condition are debatable.

Some researchers suggested that atherosclerosis may be caused by long-term high blood pressure,
high cholesterol and triglycerides (a type of fat) in the blood. Particularly, in high levels of insulin in the blood from diabetes and in exposure to chemicals from smoking tobacco.

Patients at the early stage of atherosclerosis may not experience any symptoms. However, as the disease progress, patients may have the symptoms of chest pain if the blockage occurs in an artery of the heart (coronary artery) and leg cramps during exercise or walking if the blockage occurs in the legs.

At the advanced stage, if atherosclerosis develops in the arteries or the brain, it may cause a heart attack and stroke, respectively.

Truly, change and diet and life style not only has a strong impact in prevent early onset of atherosclerosis but also inhibits progression of the condition.


Dr.Torres N the lead scientist in the joint study of conducted by the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, said, " In many cases, diet is a major driving force, which is much easier to change and follow than other factors. It is important to establish that the first strategy to treat atherosclerosis is to modify lifestyle habits, focusing on the beneficial properties of specific nutrients" and " epidemiological, clinical and experimental studies have demonstrated that diet plays a central role in the prevention of atherosclerosis. In particular, we include information about fiber, plant sterols and stanols, niacin, taurine, olive oil, omega 3 fatty acids, antioxidants, minerals, methyl nutrients and soy"(5).

Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.

According to the UCLA-School of Medicine, Los Angeles, the effectiveness of garlic in reduced homocysteine and progression of Atherosclerosis is the result of the changing white (wEAT) and brown (bEAT) epicardial adipose tissue(a form of visceral fat deposited around the heart) in plaque stabilization.


In a placebo-controlled, double-blind, randomized trial (conducted 2005-2007), with 65 intermediate risk patients (age 60+/-9 years) treated with a capsule containing aged garlic extract (250 mg) plus Vitamin B12 (100 microg), folic acid (300 microg), Vitamin B6 (12.5 mg) and l-arginine (100 mg) daily for a 1 year, researchers found that the application exerts a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis.

(AGE) retard the progression of coronary calcification in patients with coronary artery disease in vitro and vivo,


Dr. Morihara N, the lead author at the joint study said, " Antiatherosclerotic activity of AGE is at least partly due to the suppression of inflammation and lipid deposition in the vessels during the early stage of atherosclerotic development".

The experiment of a total of 157 healthy postmenopausal women (age 65 ± 6) randomized study, 500 mg isoflavonoid-rich herbal preparation, including garlic powder, reduced risk of cardiovascular disease and atherosclerosis progression through lowering high blood cholesterol.

Although garlic prevents the development of cholesterol-induced experimental atherosclerosis and possesses the direct anti-atherogenic activity, intake of garlic supplement should be taken with care to patients with ulcer.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis by Ahmadi N1, Nabavi V, Hajsadeghi F, Zeb I, Flores F, Ebrahimi R, Budoff M.(PubMed)
(2) Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial by Budoff MJ1, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S.(PubMed)
(3) Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice by Morihara N1, Hino A2, Yamaguchi T3, Suzuki J3.(PubMed)
(4) Anti-atherosclerotic effects of garlic preparation in freeze injury model of atherosclerosis in cholesterol-fed rabbits by Sobenin IA1, Andrianova IV2, Lakunin KY3, Karagodin VP4, Bobryshev YV5, Orekhov AN6.(PubMed)
(5) Nutrition and Atherosclerosis by Torres N1, Guevara-Cruz M1, Velázquez-Villegas LA1, Tovar AR(PubMed)

The Natural Alternative to Depressants Without Inducing Any Side Effects

The use of plants for healing purposes have been predated long before the existence of modern medicine.

Herbal plants have formed a fundamental source for conventional medicine in the discovery of single-ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......


Depression is a normal response as part of our daily lives such as the loss of s job, the death of a loved one, and illness, affecting the way you eat, sleep, and the way you feel about yourself.

Over 30 million Americans suffer from depression and the amount is increasing at an alarming rate.

According to general belief, people who suffer from depression may experience some mental and physical symptoms, observed by screen assay for depression in clinical settings.

The most common mental symptoms are feeling sad without reason and guilty, emotionally out of control, trouble concentrating or remembering, lack of motivation, having negative thoughts,...., particularly, in loss of interest in usually pleasurable activities.

And most common physical symptoms include lack of energy or fatigue, difficulty performing daily activities, changes in sexual desire, appetite,.... particularly, in the change of sleep pattern or difficult to sleep.

Researchers do not know what causes of depression. Why some people are more susceptible to the syndrome while some don't. However, depression may associate a lot of different factors that affect our mental health.

According to the mapping risk factors for depression across the lifespan, the development of depression may involve a complex interplay of environmental and genetic risk factors including widowhood, physical abuse during childhood, obesity, having 4-5 metabolic risk factors, sexual dysfunction, job strain and with into consistent evidence for the causal effects of obesity, smoking, and alcohol consumption(4).

If you are experiencing some of the above symptoms, you may be at the early onset of depression. Please make that you see the related field specialist immediately.

If you are taking conventional antidepressants, such as sertraline (Zoloft), fluoxetine (Prozac, Sarafem) citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil, Pexeva, Brisdelle), fluvoxamine (Luvox), please make sure you know the adverse effects such as increased appetite, weight gain, loss of sexual desire, fatigue, drowsiness, insomnia. dry mouth, blurred vision, constipation,.....

Green tea may have a profound effect in reduced risk and treatment of depression, some scientists suggested


Green tea, a precious drink processes numbers of health benefit, known to almost everyone in Asia and Western world.

However, as yin in natural herbal medicine or food, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weakening immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

In vivo, application of green tea(GT) and GABA green tea (GGT) expressed a protective activity of against post-stroke depression (PSD), a common consequence of stroke, according to a joint study led by the Pavia University.

And, in a mouse model of post-stroke depression, GGT and GT enhance the activity in the modulation of depressive symptoms through decreased oxidative stress, increased antioxidant endogenous defenses, including polyphenol, theanine, glutamine, etc......

Also, according to a cross-sectional study of consumption of green tea and coffee ascertained with a validated dietary questionnaire and the amount of caffeine intake estimated from these beverages, conducted by the joint venture lead by the Fukuoka Women's University, green tea consumption is associated to reduce symptoms of depression, depending to amount of intake.

Compared amount intake, participants consumed ≥4 cups green tea/d had a 51% significantly lower prevalence odds of having depressive symptoms than those consumed less than 1 cup/d.

The multiple-adjusted odds for depressive symptoms comparing the highest with the lowest quartile of caffeine consumption was 0·57.

These results suggested that green tea consumption have a linear effect correlated to numbers of cup intake per day without mentioning the effects of maximum cups that patients can take.

Dr. Pham NM, the lead author in the study said, "higher consumption of green tea, coffee and caffeine may confer protection against depression".

Furthermore, in the review of Embase, PubMed, and Chinese National Knowledge Infrastructure databases from their inception through August 2014, tea consumption of more than 3 cups a day showed a significant decrease the risk of depression of 37% (RR = 0.63, 95% CI: 0.55-0.71), in compared to individuals with lower tea consumption and those with higher tea consumption.

Taking together, there is no doubt, green tea may be used as a functional food in reduced symptoms and risk of depression if consumes daily.

However, oral administration of large amount daily should be taken with care, particularly to people with yin constituent.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Green tea and coffee consumption is inversely associated with depressivesymptoms in a Japanese working population by Pham NM1, Nanri A1, Kurotani K1, Kuwahara K1, Kume A1, Sato M2, Hayabuchi H3, Mizoue T1. (PubMed)
(2) Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression by Di Lorenzo A1, Nabavi SF2, Sureda A3, Moghaddam AH4, Khanjani S4, Arcidiaco P5, Nabavi SM2, Daglia M1. (PubMed)
(3) Effect of green tea on reward learning in healthy individuals: a randomized, double-blind, placebo-controlled pilot study by Zhang Q1, Yang H, Wang J, Li A, Zhang W, Cui X, Wang K.(PubMed)
(4) Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies by Köhler CA1, Evangelou E2, Stubbs B3, Solmi M4, Veronese N5, Belbasis L6, Bortolato B7, Melo MCA1, Coelho CA1, Fernandes BS8, Olfson M9, Ioannidis JPA10, Carvalho AF(PubMed)

How to Prevent Onset of Oral Cancer Naturally

Chickpeas lectin may have a profound effect in ameliorated risk and treatment of oral cancer, some scientists suggested.

Garbanzo beans also are known as chickpea is an edible legume of genus Cicer belongings to the family Fabaceae.

The bean is considered as one of the legumes containing a high amount of protein and minerals.

It is one of the earliest cultivated vegetables, native to the Middle East.

Oral cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the mouth region. At the later stage, the cancerous cell may travel a distance away from the original site to infect healthy tissues and organs.

Investigation of the process of chickpea lectin in reduced oral cell proliferation and tumor expansion
may involve the expression of several aspects and mechanisms.

According to the All India Institute of Medical Sciences, chickpeas inhibited proliferation of human oral carcinoma cells at the concentration of 37.5 μg/mL (IC50) and no toxic effect.

Further analysis, chickpeas anti-cancer activity probably was a result of the pro-apoptotic effect induced by photochemical agent lectin found abundantly in the legume.

Lectin is types of protein with the important function of binding to cell membranes and influence cell-cell interaction.

On experiential oral cancer cell line, injection of leptin showed a significant effect in inhibition of the p38α MAP kinase-activated under cellular stresses in response to inflammatory cytokines and involved function in the control of many other aspects of the physiology of the cell, such as control of cell cycle or cytoskeleton remodelling,.. for cell survival of the cancer in presence of substrate (ATP).

By blocking the physiological expression of a cancer cell, lectin reduced the cell proliferation and subsequently, shrinking the cancer site.

Furthermore, a phytochemical lectin isolated from chickpeas also demonstrated a binding affinity with p38α in regulated the production of certain inflammatory cytokines such as tumor necrosis factor (TNF), interleukin (IL)-1, IL-6 which may have certain effects in the induction of cancer growth.
The kinase p38α MAPK (p38α) is a pro-apoptotic enzyme. played a pivotal role in many biological processes, including protecting the cells in responses to inflammation and injury,

Specifically, in the influence of the production of inflammatory cytokines by p38α, lectin regulated the potent pro-inflammatory cytokine produced by cells of the innate immune system IL-1β in the induction of tumor growth and metastasis in cells under prolong period of inflammation.

According to general belief, many cancers have been found to arise from sites of infection, chronic irritation and inflammation.

In tumor necrosis factor alpha TNF-α, application of chemical lectin to oral cancer site suppressed the inflammatory expression of the protein in induced cell survival and proliferation and promoted the pro-apoptotic function of TNF-α in a program of cell death and cell cycle arrest.

Tumor necrosis factor alpha TNF-α is cell signal protein with function in induced inflammation in the acute phase of injuring and in numbers of cellular process, including cell survival, proliferation, differentiation, and death.

Importantly, the binding of kinase p38α MAPK also activated the function of IL-6, in inhibiting the factors in the induced production of inflammatory cytokines which have a negative impact in oral cell oncogenesis and enhance the expression of boosting T cell trafficking to tumor sites to induce the cytotoxic effect.

IL-6, an interleukin with duo functions in both pro-inflammatory cytokines and anti-inflammatory myokines,

Taken together, chickpea lectin may be considered as a functional food in the prevention of oral cancer.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens by Kumar S1, Kapoor V2, Gill K1, Singh K1, Xess I3, Das SN2, Dey S1(PubMed)
(2) Cell surface interaction of annexin A2 and galectin-3 modulates epidermal growth factor receptor signaling in Her-2 negative breast cancer cells by Shetty P1,2, Bargale A3,4, Patil BR5, Mohan R6, Dinesh US7, Vishwanatha JK8, Gai PB9, Patil VS3,4, Amsavardani TS10. (PubMed)
(3) Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms by Ochoa-Alvarez JA1, Krishnan H1, Pastorino JG1, Nevel E1, Kephart D1, Lee JJ1, Retzbach EP1, Shen Y1, Fatahzadeh M2, Baredes S3, Kalyoussef E3, Honma M4, Adelson ME5, Kaneko MK6, Kato Y6, Young MA1, Deluca-Rapone L1, Shienbaum AJ1, Yin K1, Jensen LD7, Goldberg GS1. (PubMed)

Dried Beans Protect Cell Integrity And DNA Transcription Against Most Types Of Cancer Onset, Medline Studies Revealed

Adding a portion of dried beans into your diet may have a potential effect in reduced risk of cancers onset, according to the Division of Cancer Prevention, National Cancer Institute.

Dried beans are a nutritionally mighty member of the legume family, belonging to the family Fabaceae.

The healthy sources of dried legume, including protein, fibers, vitamins and minerals such as dietary fiber, fat, protein, vitamin A ( beta-carotene, lutein and zeaxanthin), B vitamins, vitamin C, calcium, iron, magnesium, phosphorus, potassium, ... and zinc can be included in any one diet,

Certain genetic mutations may have significant influences in the risk of cancers, such as BRCA1 and BRCA2 genes which can elevate the risk of breast and ovarian cancers.

According to statistic, women who carry mutated gene BRCA1 and 2 have a 50 to 85 percent increased risk of developing the disease by age of 70.

Other causes of cancer are unknown, however, researchers suggested that smoking and use of tobacco, unhealthy diet, family history, inactive physical activity, long-term exposure to sun and other types of radiation, infected viruses, and infectious diseases are some of the potential risk factors that may have a strong impact on the development of cancers.

Cancer is a class of diseases characterized by cell growth uncontrollably and disorderly, affecting all the organs and tissue.

Depending on its invasive nature, some cancers can travel a distance away from the original site to infect other parts of the body.

In the study to investigate 490,802 United States participants of the NIH-AARP Diet and Health cohort using Cox proportional hazard models adjusted for potential confounders and during 2,193,751 person-years of follow-up from 1995/1996-2000, researchers found that
*. Intake of vegetables shows a significant effect in reduced risk of certain types of cancer.

* The relative hazard ratio risk of cancers was reduced to .95 in compared to control

*. Risk of cancers is reduced substantially as shown in the highest tertile of Leguminosae group (dried beans, string beans, and peas, 0.80, 0.67-0.96) compared to other groups.

Dried bean and string bean with abundant fiber scored the lower and lowerest relative risk ratio in compared to peas and other kinds of vegetables.

Further analysis of diets of African-American men and women, undergoing colonoscopies in order to examine the relationship between selected dietary factors and the risk for colon polyps, according to the multiple logistic regression model used to adjust for potential confounding variables and to determine which factors influence colorectal adenoma risk, researchers said, " consumption of legumes such as dried beans, split peas, or lentils was negatively associated with risk (of cancers)" and "Legumes are a good source of dietary fiber and of phytochemical compounds that may play a role in reducing adenoma formation or growth".

Once again, dried beans exerted the highest effect in reduced risk of colorectal adenoma in compared to other types of legume.

Interestingly, in broader scope of further exploration of the association between legume intake and cancer risk in a case-control study of 11 cancer sites in Uruguay between 1996 and 2004, including 3,539 cancer cases and 2,032 hospital controls, researchers suggested, intake of legume including dried peas demonstrate a substantially decreased risk of stomach and prostate cancer and other forms of cancer, including
*. Cavity and pharynx cancer had a relative odd risk ratio of OR=0.48

*. Esophagus cancer with OR = 0.54

*. Larynx cancer with OR = 0.55

*. Upper aerodigestive tract cancer with OR = 0.50

*. Stomach cancer with OR = 0.69

*. Colorectum cancer with OR = 0.43

*. Kidney cancer relative had an odd risk ratio of.OR = 0.41

* With relative odd risk ratio of .68 on all sites combined


After adjusting to other risk factors researchers concluded, "Higher intake of legumes was associated with a decreased risk of several cancers including those of the upper aerodigestive tract, stomach, colorectum, and kidney, but not lung, breast, prostate or bladder".

These results suggested that the protective effect of dried beans in inhibited most types of cancer occurrence may be a result of improvement of host cells integrity against alternation of cells DNA transcription in the induction of cancer.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Legume intake and the risk of cancer: a multisite case-control study in Uruguay by Aune D1, De Stefani E, Ronco A, Boffetta P, Deneo-Pellegrini H, Acosta G, Mendilaharsu M.(PubMed)
(2) Legume intake and reduced colorectal adenoma risk in African-Americans by Agurs-Collins T1, Smoot D, Afful J, Makambi K, Adams-Campbell LL. (PubMed)
(3) Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study by Freedman ND1, Park Y, Subar AF, Hollenbeck AR, Leitzmann MF, Schatzkin A, Abnet CC. (PubMed)