Strawberries may be considered a functional food that blocks the plaque accumulated in the arteries, causing atherosclerosis, some scientists suggested.
Atherosclerosis is a medical condition of heart disease characterized by plaque building up in the inner wall of the arteries.
Where arteries are blood vessels that carry oxygen and nutrient-rich blood to the heart and other organs and tissue of the body and plaque is the substance made up mostly with fat, cholesterol, calcium.
According to the statistics, atherosclerosis causes 32% of deaths of heart disease. The prevalent rate of the disease onset among adults of 20 years and above is 13.8%.
Dr. Singh RB, the lead author in the assessment of diet and exercise and lifestyle on risk of atherosclerosis conducted a randomized, single-blind, controlled trial, 621 patients assigned either intervention diet A (group A, 310 patients) or control diet B (group B, 311 patients) for a period of 24 weeks.
Where participants of group A are received: (1) a diet with a higher percentage of calories from fruits and vegetables and complex carbohydrates; (2) a higher polyunsaturated/saturated fat ratio diet; and (3) a larger amount of soluble dietary fiber, antioxidant vitamins and minerals and low saturated fat and cholesterol than group fB. Group A patients also did more physical and yogic exercises than group B.
After 24 weeks of intervention, he wrote. " There was a significant decrease in serum total cholesterol (13.3%), low-density lipoprotein cholesterol (16.9%), triglycerides (19.2%), fasting blood glucose (19.5%) and blood pressures (11.5/6.2 mm Hg) in the intervention group compared with initial levels and changes in group B".
These result suggested that a healthy diet accompanied by moderate exercise are the major factors that can substantially reduce the risk of atherosclerosis. In other words, people who follow the Western diet with physical inactivity are at higher risk to the onset of the disease.
Strawberries are a genius of Fragaria × ananassa belonging to the family Roseaceae.
They have been grown all over the world in a suitable climate for commercial profits and health benefits.
The major chemical compounds of strawberry include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
Intake of strawberry daily to improve the potent antioxidants status in the body can reduce cardiovascular risk factors, such as elevated blood pressure, hyperglycemia, dyslipidemia, and inflammation in limited studies.
Dr. Basu A, the team leader at the Oklahoma State University, Stillwater study showed that freeze-dried strawberry supplementation improves blood pressure, impaired glucose, dyslipidemia, or circulating adhesion molecules in obese subjects with metabolic syndrome, thereby lowering cardiovascular risk factors in these subjects suggested.
The randomized controlled trial included 27 subjects with metabolic syndrome (2 males and 25 females; body mass index, 37.5 +/- 2.15 kg/m(2); age, 47.0 +/- 3.0 years [means +/- SE]) consumed 4 cups of freeze-dried strawberry beverage (50 g freeze-dried strawberries approximately 3 cups fresh strawberries) or equivalent amounts of fluids (controls, 4 cups of water) daily for 8 weeks.
Strawberry supplementation intake significantly decreased total and low-density lipoprotein cholesterol (5.8 +/- 0.2 to 5.2 +/- 0.2 mmol/L and 3.5 +/- 0.2 to 3.1 +/- 0.1 mmol/L, respectively [means +/- SE], P < .05) and low-density lipoprotein particles compared to controls at the week 8.
Furthermore, strawberry supplementation also decreased circulating levels of vascular cell adhesion molecule-1 vs controls at the end of the study.
The team at the final report said, "short-term freeze-dried strawberry supplementation improved selected atherosclerotic risk factors, including dyslipidemia and circulating adhesion molecules in subjects with metabolic syndrome".
In additional examing the therapeutic roles of strawberries, blueberries, and cranberries in metabolic syndrome, a prediabetic state characterized by several cardiovascular risk factors, Dr. Basu A said, "strawberries lowering total and LDL-cholesterol, but not triglycerides, and decreasing surrogate biomarkers of atherosclerosis (malondialdehyde and adhesion molecules)".
Strawberry also extended a lowering systolic and diastolic blood pressure and lipid oxidation and improving insulin resistance but in the lesser effect compared to the blueberry
Cranberry juice selectively decreasing biomarkers of lipid oxidation (oxidized LDL) and inflammation (adhesion molecules) in metabolic syndrome compared to lesser effect in those of strawberry.
The tested berries demonstrated a potential effect in up-regulation of endothelial nitric oxide synthase activity in the protection of the cardiovascular system, reduction of renal oxidative damage, and inhibition of the activity of carbohydrate digestive enzymes or angiotensin-converting enzyme in controlling the blood pressure by regulating the volume of fluids in the blood.
Taken all together, strawberry may be considered a function\al food for the prevention of atherosclerosis and combined with the primary therapy for the treatment of the disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Reference
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome.
Basu A, Fu DX, Wilkinson M, Simmons B, Wu M, Betts NM, Du M, Lyons TJ.(PubMed)
(4) Strawberries, Blueberries, and Cranberries in the Metabolic Syndrome: Clinical Perspectives.
Basu A, Lyons TJ.(PubMed)
(5) Effects of diet and lifestyle changes on atherosclerotic risk factors after 24 weeks on the Indian Diet Heart Study by Singh RB1, Singh NK, Rastogi SS, Mani UV, Niaz MA. (PubMed)
Wednesday, January 30, 2019
Tuesday, January 29, 2019
The Herbs That Protect Digestive Function Against Gastroesophageal Reflux Disease (GERD)
Gastroesophageal reflux disease (GERD), also known as gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease, is a chronic condition characterized by liquid stomach acid refluxing back up from the stomach into the esophagus, causing heartburn.
According to the study of "Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease." by DeVault KR, Castell DO; American College of Gastroenterology, GERD is defined as symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus.
Most common symptoms are burning sensation in your chest (heartburn), chest pain, regurgitation of food or sour liquid and sensation of a lump in your throat.
In the severe case, people with GERD may experience symptoms of difficulty swallowing, lump in the throat asthma,... and chronic cough.
According to the Assaf Harofeh Medical Center, GERD may also facilitate symptoms of chest pain, similar to those with noncardiac chest pain (NCCP)(5).
The causes of GERD are not fully understood. However, some researchers suggested that obesity, poor diet, lack of physical activity, consumption of tobacco and alcohol, and respiratory diseases are associated with the prevalent risk of the diseases(6).
Properly manage diet such as two meals a day with an intake of only fluids in between, whenever the patient feels hungry or thirsty, is a useful dietary regimen for the management of GERD(7) and avoid foods and beverages that trigger GERD symptoms(8).
Use of proton pump inhibitors (PPIs) may be effective but the long-term application may cause severe side effects.
Types of food to prevent and treat Gastroesophageal reflux disease (GERD)
1. Peppermint
According to the study of the review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)." by McKay DL, Blumberg JB. posted in PubMed, in vitro, peppermint has significant antimicrobial and antiviral activities, strong antioxidant and antitumor actions, and some antiallergenic potential.
Animal model studies demonstrate a relaxation effect on gastrointestinal (GI) tissue, analgesic and anesthetic effects in the central and peripheral nervous system.
However, human studies of peppermint leaf are limited and clinical trials of peppermint tea are absent.
Adverse reactions to peppermint tea have not been reported, although caution has been urged for peppermint oil therapy in patients with GI reflux, hiatal hernia or kidney stones(1).
2. Ginger
Gingerol, is also known as gingerol, a phytochemical of Flavonoids (polyphenols) found in fresh ginger and in a variety of other plants.
Ginger has been used for thousands of years to enhance the function of digestive system and treat stomach distress including nausea, vomiting, diarrhea and indigestion, acid reflux, motion sickness, dyspepsia, etc. due to its due to its anti-inflammatory, antimicrobial and analgesic properties.
According to the study of " Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori", the methanol extract of ginger rhizome inhibited the growth of all 19 strains in vitro with a minimum inhibitory concentration range of 6.25-50 micrograms/ml.
One fraction of the crude extract, containing the gingerols, was active and inhibited the growth of all HP strains with a MIC range of 0.78 to 12.5 micrograms/ml and with significant activity against the CagA+ strains(2).
Other research of [6]-gingerol, [8]-gingerol, [10]-gingerol, and [6]-shogaol. and it effects in nausea and vomiting found that the efficiency of ginger in reducing nausea and vomiting may be based on a weak inhibitory effect of gingerols and shogaols at cholinergic M (3) receptors and serotonergic 5-HT (3) receptors.
Serotonergic 5-HT (4) receptors, which play a role in gastroduodenal motility, appear not to be involved in the action of these compound. (3)
3. Aloe Vera Juice
According to the study described in article of "Effect Of Orally Consumed Aloe Vera Juice On Gastrointestinal Function in Normal Humans", by Jeffrey Bland, Ph.D. (Linus Pauling Institute of Science & Medicine) involved ten healthy subjects - five men (median age: 42; standard deviation: 14 years), and five women (median age: 32; standard deviation: 5 years), Aloe vera juice injection promoted proper gastrointestinal function through regulating gastrointestinal pH and improved gastrointestinal motility, increased stool specific gravity, and reduced populations of certain fecal micro-organisms, including yeast(4).
4. Mastic Gum
According to the article of "Strategies to Protect Against Potential Bone-Destroying Effects"By Chris D. Meletis, ND, while much of the research on mastic gum revolves around its ability to support the health of patients with ulcers and the ability to inhibit the bacteria H. pylori, has been equally useful in patients with GERD and acid reflux(4).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16767798
(2) http://www.ncbi.nlm.nih.gov/pubmed/14666666
(3) http://www.ncbi.nlm.nih.gov/pubmed/21305447
(4) http://www.desertharvest.com/physicians/documents/DH127.pdf
(5) Comparison of central and intraesophageal factors between gastroesophageal reflux disease (GERD) patients and those with GERD-related noncardiac chest pain by Shapiro M1, Simantov R, Yair M, Leitman M, Blatt A, Scapa E, Broide E(PubMed)
(6) Epidemiology of gastroesophageal reflux disease, by Rubenstein JH1, Chen JW(PubMed)
(7) An old dietary regimen as a new lifestyle change for Gastro esophageal refluxdisease: A pilot study by Randhawa MA1, Mahfouz SA2, Selim NA2, Yar T3, Gillessen A(PubMed)
(8) Management of gastroesophageal reflux disease: lifestyle modification and alternative approaches by Eherer A1(PubMed)
According to the study of "Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease." by DeVault KR, Castell DO; American College of Gastroenterology, GERD is defined as symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus.
Most common symptoms are burning sensation in your chest (heartburn), chest pain, regurgitation of food or sour liquid and sensation of a lump in your throat.
In the severe case, people with GERD may experience symptoms of difficulty swallowing, lump in the throat asthma,... and chronic cough.
According to the Assaf Harofeh Medical Center, GERD may also facilitate symptoms of chest pain, similar to those with noncardiac chest pain (NCCP)(5).
The causes of GERD are not fully understood. However, some researchers suggested that obesity, poor diet, lack of physical activity, consumption of tobacco and alcohol, and respiratory diseases are associated with the prevalent risk of the diseases(6).
Properly manage diet such as two meals a day with an intake of only fluids in between, whenever the patient feels hungry or thirsty, is a useful dietary regimen for the management of GERD(7) and avoid foods and beverages that trigger GERD symptoms(8).
Use of proton pump inhibitors (PPIs) may be effective but the long-term application may cause severe side effects.
Types of food to prevent and treat Gastroesophageal reflux disease (GERD)
1. Peppermint
According to the study of the review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)." by McKay DL, Blumberg JB. posted in PubMed, in vitro, peppermint has significant antimicrobial and antiviral activities, strong antioxidant and antitumor actions, and some antiallergenic potential.
Animal model studies demonstrate a relaxation effect on gastrointestinal (GI) tissue, analgesic and anesthetic effects in the central and peripheral nervous system.
However, human studies of peppermint leaf are limited and clinical trials of peppermint tea are absent.
Adverse reactions to peppermint tea have not been reported, although caution has been urged for peppermint oil therapy in patients with GI reflux, hiatal hernia or kidney stones(1).
2. Ginger
Gingerol, is also known as gingerol, a phytochemical of Flavonoids (polyphenols) found in fresh ginger and in a variety of other plants.
Ginger has been used for thousands of years to enhance the function of digestive system and treat stomach distress including nausea, vomiting, diarrhea and indigestion, acid reflux, motion sickness, dyspepsia, etc. due to its due to its anti-inflammatory, antimicrobial and analgesic properties.
According to the study of " Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori", the methanol extract of ginger rhizome inhibited the growth of all 19 strains in vitro with a minimum inhibitory concentration range of 6.25-50 micrograms/ml.
One fraction of the crude extract, containing the gingerols, was active and inhibited the growth of all HP strains with a MIC range of 0.78 to 12.5 micrograms/ml and with significant activity against the CagA+ strains(2).
Other research of [6]-gingerol, [8]-gingerol, [10]-gingerol, and [6]-shogaol. and it effects in nausea and vomiting found that the efficiency of ginger in reducing nausea and vomiting may be based on a weak inhibitory effect of gingerols and shogaols at cholinergic M (3) receptors and serotonergic 5-HT (3) receptors.
Serotonergic 5-HT (4) receptors, which play a role in gastroduodenal motility, appear not to be involved in the action of these compound. (3)
3. Aloe Vera Juice
According to the study described in article of "Effect Of Orally Consumed Aloe Vera Juice On Gastrointestinal Function in Normal Humans", by Jeffrey Bland, Ph.D. (Linus Pauling Institute of Science & Medicine) involved ten healthy subjects - five men (median age: 42; standard deviation: 14 years), and five women (median age: 32; standard deviation: 5 years), Aloe vera juice injection promoted proper gastrointestinal function through regulating gastrointestinal pH and improved gastrointestinal motility, increased stool specific gravity, and reduced populations of certain fecal micro-organisms, including yeast(4).
4. Mastic Gum
According to the article of "Strategies to Protect Against Potential Bone-Destroying Effects"By Chris D. Meletis, ND, while much of the research on mastic gum revolves around its ability to support the health of patients with ulcers and the ability to inhibit the bacteria H. pylori, has been equally useful in patients with GERD and acid reflux(4).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16767798
(2) http://www.ncbi.nlm.nih.gov/pubmed/14666666
(3) http://www.ncbi.nlm.nih.gov/pubmed/21305447
(4) http://www.desertharvest.com/physicians/documents/DH127.pdf
(5) Comparison of central and intraesophageal factors between gastroesophageal reflux disease (GERD) patients and those with GERD-related noncardiac chest pain by Shapiro M1, Simantov R, Yair M, Leitman M, Blatt A, Scapa E, Broide E(PubMed)
(6) Epidemiology of gastroesophageal reflux disease, by Rubenstein JH1, Chen JW(PubMed)
(7) An old dietary regimen as a new lifestyle change for Gastro esophageal refluxdisease: A pilot study by Randhawa MA1, Mahfouz SA2, Selim NA2, Yar T3, Gillessen A(PubMed)
(8) Management of gastroesophageal reflux disease: lifestyle modification and alternative approaches by Eherer A1(PubMed)
Monday, January 28, 2019
The Potent functional Food Which Protects the Brain Against Onset of Neuro-degenerative Disorders, Scientists Reveal
Carrots may have a profound and positive effect in reducing risk, progression, and treatment of the neurodegenerative disorder, some scientists suggested.
Neurodegeneration is the progressive loss of neurons including the death of neurons, characterized by structure loss induced reduction of brain function.
The exact causes of neurodegenerative disorders are unknown. Researchers also do not why people with the same health conditions, some are susceptible to certain neurodegenerative disorders such as
Huntington's disease. ALS (amyotrophic lateral sclerosis), or Lou Gehrig's disease, Parkinson's disease or other forms of dementia, while others do not.
However, some researchers suggested that genetic mutation inherited from parents, certain illness and traumatic injury to the brain are some of the major causes of the onset of the disease.
According to Dr. Chaudhuri K, in the study of unhealthy diet and lifestyle on risk of neurodegenerative disorders, the onset of some neurodegenerative disorder was attributed to the unwholesome diet that disturbed mental health in initiating etiopathogenesis of senile dementia.
Further differentiation showed that psychological syndromes such as disturbed sleep, anxiety, tension, depression, difficulty in concentration, and memory, and the tendency to indulge in defective dietary habits, Kapha vitiating diets, and lifestyle are some predominant risk factors associated to the development of the disease.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belonging to the family Apiaceae, native to Asian and Europe.
In the evaluate the neurodegenerative disorder such as Alzheimer and Parkinson's diseases affecting the central nervous system with debilitating effect to the patient, researchers at the University Technology of Mauritius launched a study to test the efficacy of flavonoids, found in many vegetables including carrot.
Flavonoids are phytochemicals containing numbers of the member, including curcumin, lycopene, ginsenoside, vitexin, and baicalin with a proven record of anti-cancer and antioxidant and immunomodulation properties in numbers of studies.
At the results of the analysis, researchers showed that application of flavonoid to the brain ischemia patient also exerts potential neuroprotective effects by increasing neuronal viability, tissue perfusion, and cerebral blood flow and reducing ischemic-related apoptosis.
Moreover, patients treated with flavonoid also demonstrated a significantly anti-amyloidogenic effect and reduced the loss of dopaminergic neurons in the brain that has a strong implication in patients with Pakistan's disease.
After taking into account of other co and confounders, researchers concluded that flavonoid found in numbers vegetables and fruits, including carrot, may be served as a potential therapeutic agent in brain disorders.
Further differentiation of the oxidative stress which causes neurodegenerative disorder, including oxidative damage to neuron in induction of mitochondrial dysfunction and apoptosis, scientists at the Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region conducted a experiment to test the effect of lycopene, a polyunsaturated hydrocarbon with the highest antioxidant capacity compared to the other carotenoids against the expression of the diseases.
In rat model randomly divided into 5 groups: the sham group, the spinal cord injury (SCI) group and 3 SCI groups pre-treated with lycopene (5, 10, or 20mg/kg) researchers found that
* Spinal cord injury (SCI) group without treatment group displays a significant increase of malondialdehyde (MDA) content and a decrease of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) levels, compared to other groups.
Malondialdehyde (MDA) the final form of polyunsaturated fatty acids peroxidation is considered as a natural marker for oxidative stress.
* Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) are natural antioxidants produced the host body tissue with an aim to maintain the balance of ratio of reactive oxygen species and antioxidant in the body.
The expression of lower levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) is a strong indication of overabundant free radicals, compared to levels of antioxidant in the body.
* Group treated with lycopene regardless to concentration exerted an overwhelming effect in blocking the change of mRNA of the mitochondrial membrane caused by spinal cord injury (SCI), including cytochrome b and mitochondrial transcription factor A (Tfam), with functions in the induction of mitochondrial dysfunction.
Cytochrome b, a protein in the mitochondria of eukaryotic cells functioned as a part of the electron transport chain which was oxidated in this case.
Mitochondrial transcription factor A (mtTFA or Tfam), a protein with functions as a key regulator of mammalian mitochondrial (mt) DNA transcription and replication which was altered caused by the presence of MDA.
Further analysis also found that application of lycopene also reduces the risk of neurons cell apoptosis through decreased levels of pro-inflammatory and increased levels of anti-inflammatory expression in the tested rats.
These results suggested that lycopene found in vegetable including carrot significantly ameliorated oxidative damage, mitochondrial dysfunction, and cell apoptosis via some parameters indicated above.
Dr. Hu W, the lead authors said in the classification of doses application said, " lycopene significantly ameliorated the hind limb motor disturbances in the SCI+lyco10 group and the SCI+lyco20 group compared with the SCI group".
Taken together, carrot with a high amount of bioactive flavonoids, particularly lycopene may be considered a functional food in reducing risk and treatment of various forms of the neurodegenerative disorder, including Alzheimer and Parkinson diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway by Hu W1, Wang H2, Liu Z2, Liu Y2, Wang R2, Luo X2, Huang Y3(PubMed)
(2) Flavonoids and its neuroprotective effects on brain ischemia and neurodegenerative diseases by Putteeraj M1, Lim WL2, Teoh SL3, Yahaya MF(PubMed)
(3) Evaluation of diet and life style in etiopathogenesis of senile dementia: A survey study by Chaudhuri K1, Samarakoon SM, Chandola HM, Kumar R, Ravishankar B.(PuibMed)
Neurodegeneration is the progressive loss of neurons including the death of neurons, characterized by structure loss induced reduction of brain function.
The exact causes of neurodegenerative disorders are unknown. Researchers also do not why people with the same health conditions, some are susceptible to certain neurodegenerative disorders such as
Huntington's disease. ALS (amyotrophic lateral sclerosis), or Lou Gehrig's disease, Parkinson's disease or other forms of dementia, while others do not.
However, some researchers suggested that genetic mutation inherited from parents, certain illness and traumatic injury to the brain are some of the major causes of the onset of the disease.
According to Dr. Chaudhuri K, in the study of unhealthy diet and lifestyle on risk of neurodegenerative disorders, the onset of some neurodegenerative disorder was attributed to the unwholesome diet that disturbed mental health in initiating etiopathogenesis of senile dementia.
Further differentiation showed that psychological syndromes such as disturbed sleep, anxiety, tension, depression, difficulty in concentration, and memory, and the tendency to indulge in defective dietary habits, Kapha vitiating diets, and lifestyle are some predominant risk factors associated to the development of the disease.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belonging to the family Apiaceae, native to Asian and Europe.
In the evaluate the neurodegenerative disorder such as Alzheimer and Parkinson's diseases affecting the central nervous system with debilitating effect to the patient, researchers at the University Technology of Mauritius launched a study to test the efficacy of flavonoids, found in many vegetables including carrot.
Flavonoids are phytochemicals containing numbers of the member, including curcumin, lycopene, ginsenoside, vitexin, and baicalin with a proven record of anti-cancer and antioxidant and immunomodulation properties in numbers of studies.
At the results of the analysis, researchers showed that application of flavonoid to the brain ischemia patient also exerts potential neuroprotective effects by increasing neuronal viability, tissue perfusion, and cerebral blood flow and reducing ischemic-related apoptosis.
Moreover, patients treated with flavonoid also demonstrated a significantly anti-amyloidogenic effect and reduced the loss of dopaminergic neurons in the brain that has a strong implication in patients with Pakistan's disease.
After taking into account of other co and confounders, researchers concluded that flavonoid found in numbers vegetables and fruits, including carrot, may be served as a potential therapeutic agent in brain disorders.
Further differentiation of the oxidative stress which causes neurodegenerative disorder, including oxidative damage to neuron in induction of mitochondrial dysfunction and apoptosis, scientists at the Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region conducted a experiment to test the effect of lycopene, a polyunsaturated hydrocarbon with the highest antioxidant capacity compared to the other carotenoids against the expression of the diseases.
In rat model randomly divided into 5 groups: the sham group, the spinal cord injury (SCI) group and 3 SCI groups pre-treated with lycopene (5, 10, or 20mg/kg) researchers found that
* Spinal cord injury (SCI) group without treatment group displays a significant increase of malondialdehyde (MDA) content and a decrease of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) levels, compared to other groups.
Malondialdehyde (MDA) the final form of polyunsaturated fatty acids peroxidation is considered as a natural marker for oxidative stress.
* Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) are natural antioxidants produced the host body tissue with an aim to maintain the balance of ratio of reactive oxygen species and antioxidant in the body.
The expression of lower levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) is a strong indication of overabundant free radicals, compared to levels of antioxidant in the body.
* Group treated with lycopene regardless to concentration exerted an overwhelming effect in blocking the change of mRNA of the mitochondrial membrane caused by spinal cord injury (SCI), including cytochrome b and mitochondrial transcription factor A (Tfam), with functions in the induction of mitochondrial dysfunction.
Cytochrome b, a protein in the mitochondria of eukaryotic cells functioned as a part of the electron transport chain which was oxidated in this case.
Mitochondrial transcription factor A (mtTFA or Tfam), a protein with functions as a key regulator of mammalian mitochondrial (mt) DNA transcription and replication which was altered caused by the presence of MDA.
Further analysis also found that application of lycopene also reduces the risk of neurons cell apoptosis through decreased levels of pro-inflammatory and increased levels of anti-inflammatory expression in the tested rats.
These results suggested that lycopene found in vegetable including carrot significantly ameliorated oxidative damage, mitochondrial dysfunction, and cell apoptosis via some parameters indicated above.
Dr. Hu W, the lead authors said in the classification of doses application said, " lycopene significantly ameliorated the hind limb motor disturbances in the SCI+lyco10 group and the SCI+lyco20 group compared with the SCI group".
Taken together, carrot with a high amount of bioactive flavonoids, particularly lycopene may be considered a functional food in reducing risk and treatment of various forms of the neurodegenerative disorder, including Alzheimer and Parkinson diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Neuroprotective effects of lycopene in spinal cord injury in rats via antioxidative and anti-apoptotic pathway by Hu W1, Wang H2, Liu Z2, Liu Y2, Wang R2, Luo X2, Huang Y3(PubMed)
(2) Flavonoids and its neuroprotective effects on brain ischemia and neurodegenerative diseases by Putteeraj M1, Lim WL2, Teoh SL3, Yahaya MF(PubMed)
(3) Evaluation of diet and life style in etiopathogenesis of senile dementia: A survey study by Chaudhuri K1, Samarakoon SM, Chandola HM, Kumar R, Ravishankar B.(PuibMed)
Sunday, January 27, 2019
Green Tea, The Beverage In the Alleviated Symptoms, Reduces Risk and Treatment of Polymyalgia Rheumatica (PMR)
Green tea may have a therapeutic and positive effect in reducing the symptoms, risk, progression, and treatment of polymyalgia rheumatica (PMR), some scientists suggested.
Polymyalgia rheumatica an inflammatory disease with muscle pain and stiffness, especially in the shoulders, affecting mostly older adults beyond the age of 65.
The exact causes of polymyalgia rheumatica are unknown. However, researchers do know that certain prevalent risk factors are associated with the onset of diseases, such as age, family history, gender, ethnicity and exposure to environmental weather.
Genetic mutations inherited from the parents are also the major risk factor for the development of polymyalgia arthritis such as ICAM-1 (intercellular adhesion molecule 1), RANTES (regulated upon activation, normal T cell expressed, and presumably secreted).
It is important to know that Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) share the common identity, frequently related conditions in people generally over 50 years of age, according to the Dr. Miguel A Gonzalez-Gay in the study of " Genetic epidemiology: Giant cell arteritis and polymyalgia rheumatica".
Symptoms of PMR are depending on the severity of the condition, including aches or pain shoulders, neck, upper arms, buttocks, hips or thighs, and stiffness in affected areas.
People with PMR also experience pain in the morning or after being inactive for a time, limited range of motion in the affected areas.
If you have some of the above symptoms, please check with your doctor to rule out the PMR possibility.
Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and the Western world.
In an animal study of inflammatory diseases induced by injection of LPS, researchers found that application of green tea bioactive polyphenols EGCG improves antioxidant status of the host and decreases the production of inflammatory factors, including PMR through its antioxidant properties.
Further analysis suggested that application of EGCG reduced symptoms of inflammation such as pain, tension, stiffness, swelling of the infectious site without affecting the function of immune system in the protection against microorganisms invasion through inhibiting over-expression of tumor necrosis alpha(TNF-α) involved in the systematic inflammatory response to the acute phase of infection.
The bioactive compound also inhibited reactive oxygen species (ROS) in stimulating the production of inflammatory cytokines through stopping the free radicals chain reactions that facilitate inflammation and the precipitate skeletal muscle dysfunction and degradation by infiltrating immune cells to induce direct injury to muscle tissue.
In fact, overproduction of ROS increased expression of mitochondria, NAD(P)H oxidases, xanthine oxidoreductases, and nitric oxide synthases can cause an imbalance of the free radicals and antioxidant ratio, in orchestrated oxidative stress to muscle cells.
The further evaluation suggested that green tea EGCG also reduced expression of interleukin 6 (IL-6), with function in response to infections and tissue injuries.
Long-term overproduction of IL 6 due to the duo factors as a pro and anti-inflammatory protein may increase high-level concentrations of serum amyloid A (SAA), which has been found to induce serious complications of several chronic inflammatory diseases through the generated and deposited amyloid A amyloidosis into the extracellular space in an abnormal, insoluble, fibrillar form,
Moreover, EGCG also attenuated levels of nuclear factor kappa B (NF-κB) in the regulation of innate and adaptive immune functions and served as a pivotal mediator of inflammatory responses through activation of tumor necrosis factor alpha (TNF-α) in promoting muscle wasting, leading to muscle atrophy in the induction of pain and stiffness and swelling.
Importantly, application of green tea EGCG enhanced the natural antioxidant enzymes in the host such as glutathione, an antioxidant enzyme produced naturally found in every cell and tissue of the body.
These actions together with antioxidant initiated by injection of green tea EGCG stimulated cell regeneration, preserved the muscle cells and tissues and prevented muscle tension to precipitate polymyalgia arthritis.
Deficiency of glutathione levels was found to associate to the early onset of polymyalgia rheumatica, inducing symptoms of pain, stiffness, achiness, fatigue, and fever.
Differentiation of the above was supported by conventional medicine corticosteroids, a powerful anti-inflammatory drugs with the function to target pro-inflammation cytokines in the relieved stiffness and pain in patients with polymyalgia arthritis.
Taken all together, green tea and its bioactive polyphenols EGCG may be considered a functional food for alleviating symptoms, risk, progression and treatment of polymyalgia rheumatica(PMR).
However, ingestion green tea supplements should be taken with extreme care as acute liver toxicity has been reported in several medical literatures.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress by Chen J1, Xu J1, Li J1, Du L1, Chen T2, Liu P1, Peng S1, Wang M1, Song H3. (PubMed)
(2) [Anti-inflammatory effects of tea-flavonoids].[Article in German] by Hoensch H1, Oertel R.(PubMed)
(3) Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. [corrected]. by Singh R1, Akhtar N, Haqqi TM. (PubMed)
Polymyalgia rheumatica an inflammatory disease with muscle pain and stiffness, especially in the shoulders, affecting mostly older adults beyond the age of 65.
The exact causes of polymyalgia rheumatica are unknown. However, researchers do know that certain prevalent risk factors are associated with the onset of diseases, such as age, family history, gender, ethnicity and exposure to environmental weather.
Genetic mutations inherited from the parents are also the major risk factor for the development of polymyalgia arthritis such as ICAM-1 (intercellular adhesion molecule 1), RANTES (regulated upon activation, normal T cell expressed, and presumably secreted).
It is important to know that Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) share the common identity, frequently related conditions in people generally over 50 years of age, according to the Dr. Miguel A Gonzalez-Gay in the study of " Genetic epidemiology: Giant cell arteritis and polymyalgia rheumatica".
Symptoms of PMR are depending on the severity of the condition, including aches or pain shoulders, neck, upper arms, buttocks, hips or thighs, and stiffness in affected areas.
People with PMR also experience pain in the morning or after being inactive for a time, limited range of motion in the affected areas.
If you have some of the above symptoms, please check with your doctor to rule out the PMR possibility.
Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and the Western world.
In an animal study of inflammatory diseases induced by injection of LPS, researchers found that application of green tea bioactive polyphenols EGCG improves antioxidant status of the host and decreases the production of inflammatory factors, including PMR through its antioxidant properties.
Further analysis suggested that application of EGCG reduced symptoms of inflammation such as pain, tension, stiffness, swelling of the infectious site without affecting the function of immune system in the protection against microorganisms invasion through inhibiting over-expression of tumor necrosis alpha(TNF-α) involved in the systematic inflammatory response to the acute phase of infection.
The bioactive compound also inhibited reactive oxygen species (ROS) in stimulating the production of inflammatory cytokines through stopping the free radicals chain reactions that facilitate inflammation and the precipitate skeletal muscle dysfunction and degradation by infiltrating immune cells to induce direct injury to muscle tissue.
In fact, overproduction of ROS increased expression of mitochondria, NAD(P)H oxidases, xanthine oxidoreductases, and nitric oxide synthases can cause an imbalance of the free radicals and antioxidant ratio, in orchestrated oxidative stress to muscle cells.
The further evaluation suggested that green tea EGCG also reduced expression of interleukin 6 (IL-6), with function in response to infections and tissue injuries.
Long-term overproduction of IL 6 due to the duo factors as a pro and anti-inflammatory protein may increase high-level concentrations of serum amyloid A (SAA), which has been found to induce serious complications of several chronic inflammatory diseases through the generated and deposited amyloid A amyloidosis into the extracellular space in an abnormal, insoluble, fibrillar form,
Moreover, EGCG also attenuated levels of nuclear factor kappa B (NF-κB) in the regulation of innate and adaptive immune functions and served as a pivotal mediator of inflammatory responses through activation of tumor necrosis factor alpha (TNF-α) in promoting muscle wasting, leading to muscle atrophy in the induction of pain and stiffness and swelling.
Importantly, application of green tea EGCG enhanced the natural antioxidant enzymes in the host such as glutathione, an antioxidant enzyme produced naturally found in every cell and tissue of the body.
These actions together with antioxidant initiated by injection of green tea EGCG stimulated cell regeneration, preserved the muscle cells and tissues and prevented muscle tension to precipitate polymyalgia arthritis.
Deficiency of glutathione levels was found to associate to the early onset of polymyalgia rheumatica, inducing symptoms of pain, stiffness, achiness, fatigue, and fever.
Differentiation of the above was supported by conventional medicine corticosteroids, a powerful anti-inflammatory drugs with the function to target pro-inflammation cytokines in the relieved stiffness and pain in patients with polymyalgia arthritis.
Taken all together, green tea and its bioactive polyphenols EGCG may be considered a functional food for alleviating symptoms, risk, progression and treatment of polymyalgia rheumatica(PMR).
However, ingestion green tea supplements should be taken with extreme care as acute liver toxicity has been reported in several medical literatures.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress by Chen J1, Xu J1, Li J1, Du L1, Chen T2, Liu P1, Peng S1, Wang M1, Song H3. (PubMed)
(2) [Anti-inflammatory effects of tea-flavonoids].[Article in German] by Hoensch H1, Oertel R.(PubMed)
(3) Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. [corrected]. by Singh R1, Akhtar N, Haqqi TM. (PubMed)
Saturday, January 26, 2019
Maternal Coffee Intake > 4 Cups/Day May Increase Risk of Miscarriage, Scientists Suggest
The risk of miscarrying is increased substantially in excessive (over 4 cups/day) coffee drinkers during pregnancy, an Asian study suggested.
A miscarriage, according to the definition is the loss of a fetus before the 20th week of pregnancy.
Believe or not, according to medical literature, as many as many as 50% of all pregnancies end in miscarriage and over 80% of miscarriages are occurring within the first three months of pregnancy.
Some researchers suggested that women who carry mutation genes associated with chromosome gains and losses during embryonic development can lead to miscarriage or the failure of IVF treatments.
Other risk factors associated with an increased risk of miscarriage include aging Age. Women who are older than age 35, previous miscarriages. smoking and excessive alcohol drinking before and during pregnancy have a higher risk of miscarriage compared to younger women,
Chronic medical health conditions such as obesity and uterine or cervical problems can also substantially increase the miscarriage risk.
Coffee, one of the most popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
In a case-controlled study conducted in Milan of 561 (72%) cases of spontaneous abortion and 877 (57%) controls, coffee drinking during the first trimester of the index pregnancy with healthy women who gave birth at term (> 37 weeks gestation) to healthy infants as control, researchers reported that the risk of miscarry is classified as follows
* Coffee intake of 1, 2 or 3, and 4 or more cups of coffee per day are associated with an increased risk of 1.2, 1.8 and 4.0, respectively, compared to nondrinkers.
* The risk of pregnancy loss also is associated with the duration in years of coffee drinking. The estimated multivariate odds ratios of spontaneous abortion were 1.1 in comparison to non-coffee intake group.
Furthermore, in the evaluated effect of caffeine in influence of miscarriage researchers at the Boston University School of Public Health, conducted a prospective cohort study included 5132 Danish women planning pregnancy, enrolled from 2007 to 2010, after carefully assessed the returned beverage consumption on questionnaires, researcher found that a significantly miscarried risk is 1.62 higher in women consuming more than 300 mg/day of caffeine per day, in compared to 1.09 in women who consume <100 mg/day. Specifically, women with daily intake of caffeine of
* <100 mg/day showed a materially associated with SAB risk of 1.09.
* 100-199mg/day showed a materially associated with SAB risk of 0,89.
* 200-299mg/day showed a materially associated with SAB risk of 1.33
Additionally, in prospective cohort study included 15,590 pregnancies from 11,072 women with no history of SAB in the Nurses' Health Study II (1991-2009) with beverage intake assessed every 4 years using a validated questionnaire in case pregnancies lost spontaneously at <20 weeks gestation, total coffee intake had a positive, linear association with SAB.
In compared to non-pre-pregnancy coffee intake, the risk of SAB increased by 20% for women consuming ≥4 servings/day.
More importantly, Dr. Gaskins AJ, the lead author said, "Pre-pregnancy coffee consumption at levels ≥4 servings/day is associated with the increased risk of SAB, particularly at weeks 8-19".
Taking together, there is no doubt that coffee may contribute to a relative risk of miscarrying for women consuming more than 4 cups per day.
Women who are pregnant between 12 to 28 weeks of gestation with excessive coffee intake habit are recommended to consult with their doctors.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Coffee consumption and risk of hospitalized miscarriage before 12 weeks of gestation by Parazzini F1, Chatenoud L, Di Cintio E, Mezzopane R, Surace M, Zanconato G, Fedele L, Benzi G.(PubMed)
(2) Caffeine and caffeinated beverage consumption and risk of spontaneous abortion by Hahn KA1, Wise LA2, Rothman KJ3, Mikkelsen EM4, Brogly SB5, Sørensen HT6, Riis AH4, Hatch EE5.(PubMed)
(3) Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion by Gaskins AJ1,2, Rich-Edwards JW3,4,5, Williams PL3,6, Toth TL7, Missmer SA3,4,8,9, Chavarro JE10,3,4.(PubMed)
A miscarriage, according to the definition is the loss of a fetus before the 20th week of pregnancy.
Believe or not, according to medical literature, as many as many as 50% of all pregnancies end in miscarriage and over 80% of miscarriages are occurring within the first three months of pregnancy.
Some researchers suggested that women who carry mutation genes associated with chromosome gains and losses during embryonic development can lead to miscarriage or the failure of IVF treatments.
Other risk factors associated with an increased risk of miscarriage include aging Age. Women who are older than age 35, previous miscarriages. smoking and excessive alcohol drinking before and during pregnancy have a higher risk of miscarriage compared to younger women,
Chronic medical health conditions such as obesity and uterine or cervical problems can also substantially increase the miscarriage risk.
Coffee, one of the most popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
In a case-controlled study conducted in Milan of 561 (72%) cases of spontaneous abortion and 877 (57%) controls, coffee drinking during the first trimester of the index pregnancy with healthy women who gave birth at term (> 37 weeks gestation) to healthy infants as control, researchers reported that the risk of miscarry is classified as follows
* Coffee intake of 1, 2 or 3, and 4 or more cups of coffee per day are associated with an increased risk of 1.2, 1.8 and 4.0, respectively, compared to nondrinkers.
* The risk of pregnancy loss also is associated with the duration in years of coffee drinking. The estimated multivariate odds ratios of spontaneous abortion were 1.1 in comparison to non-coffee intake group.
Furthermore, in the evaluated effect of caffeine in influence of miscarriage researchers at the Boston University School of Public Health, conducted a prospective cohort study included 5132 Danish women planning pregnancy, enrolled from 2007 to 2010, after carefully assessed the returned beverage consumption on questionnaires, researcher found that a significantly miscarried risk is 1.62 higher in women consuming more than 300 mg/day of caffeine per day, in compared to 1.09 in women who consume <100 mg/day. Specifically, women with daily intake of caffeine of
* <100 mg/day showed a materially associated with SAB risk of 1.09.
* 100-199mg/day showed a materially associated with SAB risk of 0,89.
* 200-299mg/day showed a materially associated with SAB risk of 1.33
Additionally, in prospective cohort study included 15,590 pregnancies from 11,072 women with no history of SAB in the Nurses' Health Study II (1991-2009) with beverage intake assessed every 4 years using a validated questionnaire in case pregnancies lost spontaneously at <20 weeks gestation, total coffee intake had a positive, linear association with SAB.
In compared to non-pre-pregnancy coffee intake, the risk of SAB increased by 20% for women consuming ≥4 servings/day.
More importantly, Dr. Gaskins AJ, the lead author said, "Pre-pregnancy coffee consumption at levels ≥4 servings/day is associated with the increased risk of SAB, particularly at weeks 8-19".
Taking together, there is no doubt that coffee may contribute to a relative risk of miscarrying for women consuming more than 4 cups per day.
Women who are pregnant between 12 to 28 weeks of gestation with excessive coffee intake habit are recommended to consult with their doctors.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Coffee consumption and risk of hospitalized miscarriage before 12 weeks of gestation by Parazzini F1, Chatenoud L, Di Cintio E, Mezzopane R, Surace M, Zanconato G, Fedele L, Benzi G.(PubMed)
(2) Caffeine and caffeinated beverage consumption and risk of spontaneous abortion by Hahn KA1, Wise LA2, Rothman KJ3, Mikkelsen EM4, Brogly SB5, Sørensen HT6, Riis AH4, Hatch EE5.(PubMed)
(3) Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion by Gaskins AJ1,2, Rich-Edwards JW3,4,5, Williams PL3,6, Toth TL7, Missmer SA3,4,8,9, Chavarro JE10,3,4.(PubMed)
Friday, January 25, 2019
Carrots, the Veggies with Anti Cancer Potential, Researchers Find
Carrot, the root veggie may have a potential and positive effect in blocking the proliferation of cancer cells, some scientists suggested.
Cancer is a class of chronic and medical diseases characterized by irregular and disordered cell growth in one or some tissue and organs in the body.
Most cancers start from the inner lining of the tissue of the organs then slowly spread to the deeper parts of the infected organs. At the advanced stage, most malignant cancer cells can travel a distance away from the original site to infect other healthy tissue and organs.
Most cancer diagnosed in the early have a 100% 5 years survival rate.
According to the statistic provided by the Canadian public health service, during their lifetime, nearly 1 in 2 Canadians will be diagnosed with cancer, and 1 in 4 will die from the disease.
Lung, colorectal, breast and prostate cancers account for half of all cancers diagnosed in Canada and over 25% of all cancer deaths in Canada are due to lung cancer.
The causes of cancers are unknown, however, scientists in the world agreed that there are several risk factors such as gene mutations inherited from the parents and acquired gene mutations caused by smoking, radiation, viruses, chemicals carcinogens, obesity, hormones, chronic inflammation, and physical inactivity are associated to the early onset of cancer.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belonging to the family Apiaceae, native to Asian and Europe.
In the investigation of the claim of Lebanese folk medicine that Daucus carota, also known as wild carrot has a potency for treatment of various types of cancer, researchers at the Lebanese American University, conducted an experience to identify the major compound responsible for the anti-cancer activity of DCOE.
β-2-himachalen-6-ol, a novel sesquiterpene unique to β-2-Himachalen-6-ol isolated from the Lebanese wild carrot demonstrated potent anti-cancer activity against B16F-10, Caco-2, MB-MDA-231, A549, and SF-268 cancer cells (IC50 13-4µg/ml; 58-18µM), and SF-268 cells.
Furthermore, the sesquiterpene was shown to induce cell death through apoptosis (flow cytometry), decrease 2D cell motility (wound healing assay) and 3D invasion, as well as increase cell adhesion in SF-268 cells.
Additionally, β-2-himachalen-6-ol showed very low toxicity.
These results suggested that wild carrot β-2-himachalen-6-ol may have a potential multi-mechanistic chemotherapeutic drug with high potency and safety.
Moreover, in the concerns of the mortality rate caused by gastric cancer, researchers at the Shahid Sadoughi University of Medical Sciences conducted a review by searching the multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx to determine the relationship between carrot consumption and gastric cancer.
Out of 81 articles found in the databases, only 5 studies satisfied the medical guidelines and criteria were included in the review. after taking into account co and confounders, researchers found that
* Intake of carrot regularly reduced the risk of gastric cancer by 26%.
* There is an inverse relationship between the consumption of carrots and the risk of gastric cancer.
More interestingly, regarding the inconsistent results. associated with carrot intake and prostate cancer risk, researchers at the Zhejiang University also launched a review by searching the databases of PubMed, EMBASE, Scopus, Web of Science, the Cochrane register, and the Chinese National Knowledge Infrastructure to determine whether intake of carrot may reduce the risk of prostate cancer.
At the final report, researchers found that
* Intake of carrot is associated with a significantly decreased risk of prostate cancer with the odds ratio of 0.82 which is consistency with the Shahid Sadoughi University of Medical Sciences study.
* Forr each serving per week or 10 g per day increment of carrot intake, the odds ratio of the risk of prostate cancer was 0.95, according to the dose-response meta-analysis.
The findings indicated that intake of carrot may have a potential effect in reducing the risk of the onset of cancers.
However, due to the limited number of cohort studies and substantial heterogeneity observed between studies in this meta-analysis, further well-designed prospective studies are warranted to confirm the findings from the studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1)β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot by Taleb RI1, Najm P2, Shebaby W2, Boulos JC2, Demirdjian S2, Hariri E2, El-Sibai M2, Daher C2, Mroueh M3(PubMed)
(2) Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis by Fallahzadeh H1, Jalali A2, Momayyezi M1, Bazm S3.(PubMed)
(3) Dietary carrot consumption and the risk of prostate cancer. by Xu X1, Cheng Y, Li S, Zhu Y, Xu X, Zheng X, Mao Q, Xie L.(PubMed)
Cancer is a class of chronic and medical diseases characterized by irregular and disordered cell growth in one or some tissue and organs in the body.
Most cancers start from the inner lining of the tissue of the organs then slowly spread to the deeper parts of the infected organs. At the advanced stage, most malignant cancer cells can travel a distance away from the original site to infect other healthy tissue and organs.
Most cancer diagnosed in the early have a 100% 5 years survival rate.
According to the statistic provided by the Canadian public health service, during their lifetime, nearly 1 in 2 Canadians will be diagnosed with cancer, and 1 in 4 will die from the disease.
Lung, colorectal, breast and prostate cancers account for half of all cancers diagnosed in Canada and over 25% of all cancer deaths in Canada are due to lung cancer.
The causes of cancers are unknown, however, scientists in the world agreed that there are several risk factors such as gene mutations inherited from the parents and acquired gene mutations caused by smoking, radiation, viruses, chemicals carcinogens, obesity, hormones, chronic inflammation, and physical inactivity are associated to the early onset of cancer.
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belonging to the family Apiaceae, native to Asian and Europe.
In the investigation of the claim of Lebanese folk medicine that Daucus carota, also known as wild carrot has a potency for treatment of various types of cancer, researchers at the Lebanese American University, conducted an experience to identify the major compound responsible for the anti-cancer activity of DCOE.
β-2-himachalen-6-ol, a novel sesquiterpene unique to β-2-Himachalen-6-ol isolated from the Lebanese wild carrot demonstrated potent anti-cancer activity against B16F-10, Caco-2, MB-MDA-231, A549, and SF-268 cancer cells (IC50 13-4µg/ml; 58-18µM), and SF-268 cells.
Furthermore, the sesquiterpene was shown to induce cell death through apoptosis (flow cytometry), decrease 2D cell motility (wound healing assay) and 3D invasion, as well as increase cell adhesion in SF-268 cells.
Additionally, β-2-himachalen-6-ol showed very low toxicity.
These results suggested that wild carrot β-2-himachalen-6-ol may have a potential multi-mechanistic chemotherapeutic drug with high potency and safety.
Moreover, in the concerns of the mortality rate caused by gastric cancer, researchers at the Shahid Sadoughi University of Medical Sciences conducted a review by searching the multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx to determine the relationship between carrot consumption and gastric cancer.
Out of 81 articles found in the databases, only 5 studies satisfied the medical guidelines and criteria were included in the review. after taking into account co and confounders, researchers found that
* Intake of carrot regularly reduced the risk of gastric cancer by 26%.
* There is an inverse relationship between the consumption of carrots and the risk of gastric cancer.
More interestingly, regarding the inconsistent results. associated with carrot intake and prostate cancer risk, researchers at the Zhejiang University also launched a review by searching the databases of PubMed, EMBASE, Scopus, Web of Science, the Cochrane register, and the Chinese National Knowledge Infrastructure to determine whether intake of carrot may reduce the risk of prostate cancer.
At the final report, researchers found that
* Intake of carrot is associated with a significantly decreased risk of prostate cancer with the odds ratio of 0.82 which is consistency with the Shahid Sadoughi University of Medical Sciences study.
* Forr each serving per week or 10 g per day increment of carrot intake, the odds ratio of the risk of prostate cancer was 0.95, according to the dose-response meta-analysis.
The findings indicated that intake of carrot may have a potential effect in reducing the risk of the onset of cancers.
However, due to the limited number of cohort studies and substantial heterogeneity observed between studies in this meta-analysis, further well-designed prospective studies are warranted to confirm the findings from the studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1)β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot by Taleb RI1, Najm P2, Shebaby W2, Boulos JC2, Demirdjian S2, Hariri E2, El-Sibai M2, Daher C2, Mroueh M3(PubMed)
(2) Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis by Fallahzadeh H1, Jalali A2, Momayyezi M1, Bazm S3.(PubMed)
(3) Dietary carrot consumption and the risk of prostate cancer. by Xu X1, Cheng Y, Li S, Zhu Y, Xu X, Zheng X, Mao Q, Xie L.(PubMed)
Thursday, January 24, 2019
Green Tea Protects the Child Joints Against the Onset of Juvenile Arthritis
Green tea may have a therapeutic and positive effect in reducing risk, progression, and treatment of juvenile arthritis, some scientists suggested.
Juvenile arthritis is an inflammatory disease affecting the synovium in children aged 16 or younger.
In other words, it is an autoimmune disorder caused by the immune system attacks some of the body's own healthy cells and tissues, in this case, the immune system attacks the joint tissue in the juvenile.
Genes that are associated with the risk of juvenile idiopathic arthritis include HLA-A. HLA-B. HLA-DPB1. HLA-DQA1. HLA-DQB1. HLA-DRB1. IL2RA. IL6, according to the National Institute of Health.
According to the statistic, the most common form of juvenile idiopathic arthritis (JIA), affects over 50,000 children in the United States alone.
Juvenile Arthritis shares the common symptoms of adult arthritis, including pain, stiffness, swelling, fever, skin rash and in the serious case. The condition can also cause some complications such as pericarditis, hemolytic anemia, macrophage activation syndrome (MAS), and endarteritis
In the article "Juvenile Arthritis: Early Signs and Symptoms" By Susan Bernstein wrote, "Juvenile arthritis includes many different diseases, but one common thread between them is that they can have serious, even life-threatening impacts on a young child".
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
In the investigation of the effect of green tea extract on the oxidative state of the liver and brain of adjuvant-induced arthritic rats, a model for human rheumatoid arthritis with daily doses of 250 mg kg(-1) (59.8 mg catechins per kg) for 23 days, researchers at the State University of Maringá, found that treatment group expressed a significant activity in reducing the protein and lipid damage in liver, brain, and plasma, caused by ROS expression in induction of oxidation which has been found with associated to the progression of arthritis.
Injection of green tea extract also enhanced the overexpression of antioxidant defenses, found in low levels in patients with arthritis through restoration of the glutathione (GSH) associated to the important function in preventing damage to important cellular components caused by reactive oxygen species and protein thiol levels in reducing cellular oxidation through chelative and detoxified activities and improved natural antioxidant enzymes, produced by the body.
Furthermore, green tea extract also inhibited the levels of glucose 6-phosphate dehydrogenase, which is increased in the liver in patients with arthritis, one of the major risk factor for the development of arthritis.
These results suggested that application of green tea exerted a significantly profound effect in the liver and brain of patients suffering from rheumatoid arthritis through reduced overexpression of oxidative stress in precipitated injury to lipids and proteins.
Some researchers suggested that by modifying the metabolic function in lipid and protein, green tea extract exhibited a strong protective effect in reducing the symptoms and progression of arthritis.
According to the study of University of Health System of green tea effect in patients with rheumatoid
arthritis, injection of green tea extract demonstrated a therapeutic effect in patient's synovial fibroblast of the lining tissue which surround the capsule of the joint by inhibiting the production of IL-1B, a prototypic proinflammatory cytokines in response to acute and chronic inflammation. Overexpression of IL-1B is associated with the contribution of joint damage.
Interestingly, in the study of adolescent male Wistar rats 12-week exposure to Cd and Pb (7mg Cd and 50mg Pb in 1kg of the diet randomly assigned to 12 to each group, as positive control received without Cd, Pb and teas, a negative control group received Cd and Pb, and groups supplemented additionally with green (GT), black (BT), red (RT), and white tea (WT), researchers indicated that application of tea significant inhibits the decreased levels of the geometric(shape) and densitometric(density) parameters and total thickness of articular cartilage caused by Cd and Pb in compared to the negative control group.
Tea injection group also displayed a huge improvement in mechanical endurance, growth plate thickness, and trabecular histomorphometry depending on the tea type.
Due to the limitation of the study, Dr. Tomaszewska E, the lead researcher said, " It is difficult to indicate which tea has the best protective effects on bone and hyaline cartilage against heavy metal action".
More importantly, in the examine some major factors in contributing juvenile arthritis, green tea rich in catechins (Healthy green tea) in animal study, green tea injection restored these biomarkers of cytokine genes (IL-1A, IL-2, IFN-alpha, FGF-alpha, TNF-alpha) to near normal levels, thus preventing or attenuating the development of a certain type of inflammatory arthritis.
Taken all together, green tea and its bioactive polyphenols may be considered a functional food for reduction of the early onset, progression and combined with standard therapy for treatment of juvenile and adult arthritis.
However, the intake of green tea supplement should be taken with exceptional care as acute liver toxicity has been reported in numbers of medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis by de Almeida Gonçalves G1, de Sá-Nakanishi AB, Wendt MM, Comar JF, Bersani Amado CA, Bracht A, Peralta RM. (PubMed)
(2) (Alteration in bone geometric and mechanical properties, histomorphometrical parameters of trabecular bone, articular cartilage, and growth plate in adolescent rats after chronic co-exposure to cadmium and lead in the case of supplementation with green, black, red and white tea by Tomaszewska E1, Dobrowolski P2, Winiarska-Mieczan A3, Kwiecień M3, Tomczyk A4, Muszyński S5, Radzki R4.(PubMed)
(3) Green tea with a high catechin content suppresses inflammatory cytokine expression in the galactosamine-injured rat liver by Abe K1, Ijiri M, Suzuki T, Taguchi K, Koyama Y, Isemura M.(PubMed)
Juvenile arthritis is an inflammatory disease affecting the synovium in children aged 16 or younger.
In other words, it is an autoimmune disorder caused by the immune system attacks some of the body's own healthy cells and tissues, in this case, the immune system attacks the joint tissue in the juvenile.
Genes that are associated with the risk of juvenile idiopathic arthritis include HLA-A. HLA-B. HLA-DPB1. HLA-DQA1. HLA-DQB1. HLA-DRB1. IL2RA. IL6, according to the National Institute of Health.
According to the statistic, the most common form of juvenile idiopathic arthritis (JIA), affects over 50,000 children in the United States alone.
Juvenile Arthritis shares the common symptoms of adult arthritis, including pain, stiffness, swelling, fever, skin rash and in the serious case. The condition can also cause some complications such as pericarditis, hemolytic anemia, macrophage activation syndrome (MAS), and endarteritis
In the article "Juvenile Arthritis: Early Signs and Symptoms" By Susan Bernstein wrote, "Juvenile arthritis includes many different diseases, but one common thread between them is that they can have serious, even life-threatening impacts on a young child".
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
In the investigation of the effect of green tea extract on the oxidative state of the liver and brain of adjuvant-induced arthritic rats, a model for human rheumatoid arthritis with daily doses of 250 mg kg(-1) (59.8 mg catechins per kg) for 23 days, researchers at the State University of Maringá, found that treatment group expressed a significant activity in reducing the protein and lipid damage in liver, brain, and plasma, caused by ROS expression in induction of oxidation which has been found with associated to the progression of arthritis.
Injection of green tea extract also enhanced the overexpression of antioxidant defenses, found in low levels in patients with arthritis through restoration of the glutathione (GSH) associated to the important function in preventing damage to important cellular components caused by reactive oxygen species and protein thiol levels in reducing cellular oxidation through chelative and detoxified activities and improved natural antioxidant enzymes, produced by the body.
Furthermore, green tea extract also inhibited the levels of glucose 6-phosphate dehydrogenase, which is increased in the liver in patients with arthritis, one of the major risk factor for the development of arthritis.
These results suggested that application of green tea exerted a significantly profound effect in the liver and brain of patients suffering from rheumatoid arthritis through reduced overexpression of oxidative stress in precipitated injury to lipids and proteins.
Some researchers suggested that by modifying the metabolic function in lipid and protein, green tea extract exhibited a strong protective effect in reducing the symptoms and progression of arthritis.
According to the study of University of Health System of green tea effect in patients with rheumatoid
arthritis, injection of green tea extract demonstrated a therapeutic effect in patient's synovial fibroblast of the lining tissue which surround the capsule of the joint by inhibiting the production of IL-1B, a prototypic proinflammatory cytokines in response to acute and chronic inflammation. Overexpression of IL-1B is associated with the contribution of joint damage.
Interestingly, in the study of adolescent male Wistar rats 12-week exposure to Cd and Pb (7mg Cd and 50mg Pb in 1kg of the diet randomly assigned to 12 to each group, as positive control received without Cd, Pb and teas, a negative control group received Cd and Pb, and groups supplemented additionally with green (GT), black (BT), red (RT), and white tea (WT), researchers indicated that application of tea significant inhibits the decreased levels of the geometric(shape) and densitometric(density) parameters and total thickness of articular cartilage caused by Cd and Pb in compared to the negative control group.
Tea injection group also displayed a huge improvement in mechanical endurance, growth plate thickness, and trabecular histomorphometry depending on the tea type.
Due to the limitation of the study, Dr. Tomaszewska E, the lead researcher said, " It is difficult to indicate which tea has the best protective effects on bone and hyaline cartilage against heavy metal action".
More importantly, in the examine some major factors in contributing juvenile arthritis, green tea rich in catechins (Healthy green tea) in animal study, green tea injection restored these biomarkers of cytokine genes (IL-1A, IL-2, IFN-alpha, FGF-alpha, TNF-alpha) to near normal levels, thus preventing or attenuating the development of a certain type of inflammatory arthritis.
Taken all together, green tea and its bioactive polyphenols may be considered a functional food for reduction of the early onset, progression and combined with standard therapy for treatment of juvenile and adult arthritis.
However, the intake of green tea supplement should be taken with exceptional care as acute liver toxicity has been reported in numbers of medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis by de Almeida Gonçalves G1, de Sá-Nakanishi AB, Wendt MM, Comar JF, Bersani Amado CA, Bracht A, Peralta RM. (PubMed)
(2) (Alteration in bone geometric and mechanical properties, histomorphometrical parameters of trabecular bone, articular cartilage, and growth plate in adolescent rats after chronic co-exposure to cadmium and lead in the case of supplementation with green, black, red and white tea by Tomaszewska E1, Dobrowolski P2, Winiarska-Mieczan A3, Kwiecień M3, Tomczyk A4, Muszyński S5, Radzki R4.(PubMed)
(3) Green tea with a high catechin content suppresses inflammatory cytokine expression in the galactosamine-injured rat liver by Abe K1, Ijiri M, Suzuki T, Taguchi K, Koyama Y, Isemura M.(PubMed)
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