Saturday, February 16, 2019

Manaku Honey, the Potential Cartilage Repair Functional Food

Scientists may have found a golden liquid for the treatment of cartilage damage without inducing any side effects, some studies suggested.

Cartilage is an important structural component placed in the joints of bone with a function to prevent the end of the bone collided from one to another.

Cartilage is a firm tissue but is softer and much more flexible than bone.

Due to the lack of blood vessels connected to the cartilage to supply the chondrocytes with nutrients, repairing the damage of cartilage are more slowly than other tissues.


Cartilage repair is an act is to restore the surface of joint cartilage. However, how sufficiency of the works is totally depending on the degree of the damage.

In conventional medicine, cartilage damage due to a single injury, or lesion can be repaired successfully. However, with many lesions in one joint, are less likely to benefit from the surgery. cartilage, particularly in the older population.

In the article "Articular Cartilage Restoration", the American Academy of Orthopaedic Surgeons wrote, "Many procedures to restore articular cartilage are done arthroscopically" and "Some procedures require the surgeon to have more direct access to the affected area. Longer, open incisions are required. Sometimes it is necessary to address other problems in the joint, such as meniscal or ligament tears when cartilage surgery is done"

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

With an aim to find the natural ingredient or whole food for the cartilage repair in replacement of that conventional medicine with no side effects, researchers at a number of institutes conducted a joint study to evaluate the nature-derived hydrogels, a promising class of scaffolds for cartilage tissue engineering, mimicking the native cellular microenvironment.

Manuka honey made hydrogels able to inhibit the proliferation of S. aureus and S. epidermidis clinical isolates and no cytotoxic effects were detected on human mesenchymal stem cells seeded on the hydrogels.
Manuka honey initiated a consistent expression of collagen II and high synthesis of
Sulfated glycosaminoglycans (GAGs) and proteoglycans, thus indicating the formation of the cartilage matrix.


Where Sulfated glycosaminoglycans and proteoglycans are considered promising artificial extracellular matrix components to improve the regeneration of tissues, such as cartilage repair.


These results suggested Manuka honey processes a similar action as those of synthetic substances used for the treatment to improve cartilage regeneration.


In order to understand the effect of Manuka honey in cartilage repair, researcher launched a differentiation of the research paper "Antibacterial effectiveness meets improved mechanical properties: Manuka Honey/Gellan Gum composite hydrogels for cartilage repair", Bonifacio et al.


And suggested that before Manuka honey can be used for the treatment of cartilage repair, there are some criteria must be met. you can view them at the sources


Due to the limitation of the study, therefore, further data collection large example size and multi-centers studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of Manuka honey cartilage repair possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

(1) Antibacterial effectiveness meets improved mechanical properties: Manuka honey/gellan gum composite hydrogels for cartilage repair by Bonifacio MA1, Cometa S2, Cochis A3, Gentile P4, Ferreira AM5, Azzimonti B6, Procino G7, Ceci E8, Rimondini L9, De Giglio E10. (PubMed)
(2) Data on Manuka Honey/Gellan Gum composite hydrogels for cartilage repair by Bonifacio MA1, Cometa S2, Cochis A3, Gentile P4, Ferreira AM4, Azzimonti B3,5, Procino G6, Ceci E7, Rimondini L3,5, De Giglio E1. (PubMed)

Friday, February 15, 2019

Herbal Arnica, the Natural Muscle Pain Reliever

Herbal Arnica may be used as a natural painkiller in alleviating pain with inducing any side effects, some scientists suggested.

Pain a natural response from the brain caused by intense or damaging stimuli with an aim to protect our body against injury or damage.

Pain can vary greatly such as mild, sharp, severe, and dull. Acute pain is the sensation that lasts for a short period of time.


Chronic pain is pain that lasts longer than 12 weeks. Most cases of chronic pain arise from an initial injury such as back injury or diseases such as rheumatoid arthritis, osteoarthritis, and fibromyalgia.


There are different types of pain, including
* Nociceptive pain is a normal response to injury of tissues such as skin, muscles, visceral organs, joints, tendons, or bones.

* Neuropathic pain is a type of pain caused by a primary lesion in the somatosensory nervous system
and

* Inflammatory pain is associated with the production of proinflammatory cytokines in response to the acute phase of infection and chronic inflammatory diseases.

Conventional medicine used for the treatment of pain are effective in improving the quality of life of patients. However, long-term use has been known to induce some common fatigue, mental cloudiness, unclear thinking, and mood change and serious cardiovascular issues, sexual dysfunction, side effects

Most common prescription painkillers are the nonsteroidal anti-inflammatory drug (NSAID) and
Opioids

Therefore, if you currently taking medication to reduce chronic pain, please make sure you know all the side effects

Arnica is a herbaceous species, genus perennial, belonging to the family Asteraceae, native to Europe and Asia.

The plant has been used in herbal medicine for centuries to treat strains, sprains, and bruises.
Colon Cancer is defined as a condition of the abnormal proliferation of cells in the colon.
Pain is a feeling triggered in the nervous system as a result of often caused by intense or damaging stimuli.

Besides containing contain helenalin as it main ingredient used as an anti-inflammatory agent in herbal medicine, the herbal plant also contains 11,13- dihydrohelenaline, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin.

In the finding, the natural topical compound for the treatment revelation of pain and a replacement of conventional a painkiller with little or no side effects, researchers at the Department of Plastic Surgery of Queen Victoria Hospital in West Sussex, examine the herb Arnica montana, in topical formulations used in the traditional medicine for pain relief.

Thirty-seven patients undergoing bilateral endoscopic carpal-tunnel release between June 1998 and January 2000 were included in a double-blind, randomized comparison of Arnica administration versus placebo.

Grip strength, wrist circumference, and perceived pain measured 1 and 2 weeks after surgery. Application of Arnica showed no difference in grip strength or wrist circumference but a significant reduction in pain experienced after 2 weeks compared to placebo.

Dr. Pumpa KL, the lead author at the University of Canberra in the study to reaffirm the use of topical Arnica gel, for the treatment of pain, evaluated the Arnica effect on the inflammation and muscle damage, and in turn, improve performance in well-trained males experiencing delayed onset muscle soreness (DOMS).


The study included twenty well-trained males matched by maximal oxygen uptake (V̇O2 Max) completed a double-blind randomized placebo-controlled trial.


Topical Arnica was applied to the skin superficial to the quadriceps and gastrocnemius muscles immediately after a downhill running protocol designed to induce DOMS.


Topical Arnica group exerted significantly less pain through muscle tenderness and VAS 72 hours post-exercise and did not affect any performance assessments or markers of muscle damage or inflammation.


Furthermore, topical Arnica used immediately after intense eccentric exercise and for the following 96 hours did not have an effect on performance or blood markers.


The doctoral team after taking into account co and confounders said, " (Topical Arnica applications) demonstrate the possibility of providing pain relief three days post-eccentric exercise".


Taken altogether, topical Arnica gel may be considered a functional herb for the prevention and treatment of muscle pain and damage due to over muscle exercises.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Use of Arnica to relieve pain after carpal-tunnel release surgery by Jeffrey SL, Belcher HJ. (PubMed)
(2) The effects of topical Arnica on performance, pain, and muscle damage after intense eccentric exercise by Pumpa KL, Fallon KE, Bensoussan A, Papalia S.(PubMed)

Wednesday, February 13, 2019

Fennel Essential Oil and Extract, The Potent Anti Hypoglycemic Remedies

Fennel may process a strong effect in preventing the abnormal rise of blood glucose in patients with diabetes, some scientists found.

In compared to hyperglycemia with an excessive amount of glucose that circulates in the blood plasma, hypoglycemia is a condition of blood sugar, that falls below the levels of the normal range.

Patient with acute hypoglycemia may experience symptoms of clumsiness, trouble talking, confusion, loss of consciousness, seizures or death.

Most cases of hyperglycemia in patients with diabetes are due poor management. However, eating more carbohydrates than usual, less physical activity compared to normal day being sick or high levels of stress in patients with diabetes also can cause blood glucose uptake.

Some researchers suggested that not getting the right dosage of insulin and glucose-lowering medication also cause increased blood glucose levels.


Long-term untreated hyperglycemia can elevate the onset of some serious complications including nerve damage, kidney damage and failure, heart disease and eye disease, particularly in food and skin problems. or retinopathy foot problems caused by damaged nerves and poor blood flow skin problems, such as bacterial and fungal infections


Fennel (Foeniculum vulgare) is a plant species belongings to the family Apiaceae (Umbelliferae), native to the Mediterranean

The plant has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

In the examine the antihyperglycemic activity of fennel essential oil in an animal model, researchers launched an investigation to evaluate of rats induced by bacterial streptozotocin.

At the concentrations of 30 mg/kg body weight, essential oil of fennel demonstrated a correction of hyperglycemia in the doses from 162.5 mg/dL to 81.97 ± 1.97 mg/dL by increased the serum of antioxidants activity of serum glutathione peroxidase from 59.72 U/g Hb to 99.60 U/g Hb produced by the host.

The application also improved the pathological changes noticed in their kidney and pancreas, compared to the control group.

After making the final adjustment, researchers suggested that the study not only reaffirms the use of essential oil of fennel for the treatment of hyperglycemia in folk medicine but also raises the possibility of essential oil inclusion in the antidiabetic drug industry.

Further analysis of the ethanolic and aqueous extracts of selected Sudanese plants, including fennel that is traditionally used to treat diabetes, researchers at the Khartoum College of Medical Sciences, suggested that fennel extract reveals a significant antioxidant activity in DPPH free radical scavenging assay.

However, injection of fennel extract exhibited the highest toxicity.


These findings indicated that although fennel extract processes a substantial and positive effect in reducing the spike of blood glucose intake and the use of the fennel extract can only be prescribed by herbalists and professionals in the related field.

Additionally, in the testing, the hypoglycemic effect of single dose of Gluconorm-5 (150, 300 and 600 mg/kg body weight) made up of five plants namely Camellia sinensis, Punica granatum, Macrotyloma uniflorum, Foeniculum vulgare and Trigonella foenum-graecum in normal, glucose loaded normal and diabetes-induced rats, researchers found that

* Fifteen days of oral feeding of the Gluconorm-5 (300 and 600 mg/kg) to diabetic rats resulted in a significant (P < 0.01) reduction of blood glucose, lipid profile, liver weight, and marker enzymes as compared to those rats in whom STZ induced toxicity was untreated.

* The diabetic rats treated with the formula showed the expanded islets compared to the untreated diabetic rats, which showed the shrunken islets.

* Treated rats received 300 mg/kg of Gluconorm-5 showed pronounced antidiabetic, antihyperlipidemic and hepatoprotective effect.

This comprehensive differentiation showed that Gluconorm-5 processes a potent antidiabetic antihyperlipidemic and hepatoprotective effect properties.

Taken altogether, fennel extract, fennel essential oil used alone or combined with other herbal antidiabetic herbal medicine can be considered an adjuvant in the treatment of hyperglycemia and diabetes mellitus.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential by Hilmi Y1, Abushama MF, Abdalgadir H, Khalid A, Khalid H(PubMed)
(3) The Dietary Furocoumarin Imperatorin Increases Plasma GLP-1 Levels in Type 1-Like Diabetic Rats by Wang LY1,2,3, Cheng KC4, Li Y5,6, Niu CS7, Cheng JT8,9, Niu HS(PubMed)
(4) Antidiabetic antihyperlipidemic and hepato-protective effect of Gluconorm-5: A polyherbal formulation in steptozotocin induced hyperglycemic rats by Gengiah K1, Hari R2, Anbu J(PubMed)

Green Tea, The Beverage Which Protects the Brain Functioning Against the Onset of Mood Disorder

Green tea may have a potential and positive effect in treating a mood disorder, some scientists suggested.

Mood disorder is a psychological condition characterized by an elevated mood, including mania or hypomania. In other words, a syndrome is a group of mental illnesses that can affect how a person feel and think of him/herself and people in the public life.

A mood disorder can be classified into depression, dysthymic disorder,... and bipolar disorder depending on the symptoms of expression.

The condition not only affects the personal life of the patient but also cause psychological and financial burdens to the immediate family members as the condition can only get worse over time.

According to the statistic in 2017, over 2.6 millions Canadian age 12 and over were diagnosed with mood disorders, affecting over 8% of general population. Sadly, about one in seven Canadian will experience a mood disorder at some point in their life.

The exact causes of mood disorders are unknown, however, there are some underlying factors that can elevate the risk of the condition, including family history, previous mood disorder, depression, certain medical conditions and long-term use of some medication.


Symptoms of mood disorders are totally depending to types of the syndrome. If you are experiencing symptoms of feelings of hopelessness, long-term trouble sleeping or daytime sleepiness, poor concentration and trouble concentrating or making decisions accompanied by physical symptoms of fatigue or low energy, you may have mood disorders. Please check with your doctor to rule out the possibility.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.


In the concerns of the widespread of mental disorders, researchers at the Elsevier GmbH.lauched an investigation to examine the effects of green tea or green tea extracts, l-theanine and epigallocatechin gallate both components of green tea-on general neuropsychology, on the sub-category cognition and on brain functions in humans.

By searching the database of medical literature in PubMed for qualified studies that are satisfied the guidelines and criteria set by the PRISMA statement.

Out of 21 selected studies, 4 were randomized controlled trials, 12 were cross-over studies (both assessed with an adapted version of the DELPHI-list), 4 were cross-sectional studies and one was a cohort study (both assessed with an adapted version of the Newcastle-Ottawa assessment scale).

After assessing the results of all studies, researchers found that injection of green tea exerts a significant effect in psychopathological symptoms (e.g. reduction of anxiety), cognition (e.g. benefits in memory and attention) and brain function (e.g. activation of working memory seen in functional MRI).

Further analysis also suggested that the effects of green tea may be attributed to the combined influence of both caffeine and l-theanine, as separate administration of either substance is found to have a lesser impact.


Moreover, in the systematic review and meta-analysis conducted on 11 randomized placebo-controlled human studies of acute effects of tea constituents L-theanine and epigallocatechin gallate, administered alone or in combination with caffeine, on cognitive function and mood, researchers discovered that* Combined caffeine and L-theanine demonstrated some moderate effects in the first 2 hours postdose, on ladder alertness, attentional switching accuracy, and, to a lesser extent, some unisensory and multisensory attentional outcomes.

* Caffeine and L-theanine doses revealed trends toward greater change in effect size for caffeine dose than for L-theanine dose, particularly during the first hour postdose.

Additionally, in the study to evaluate whether tea has any effect on mood and performance benefits, such as relaxation and concentration, researchers at the From Unilever Research and Development also conducted an extensive search of studies with consistent evidence for improved attention.

At the final report, researchers concluded after taking into account co and confounders
* Tea consumption also consistently improved self-reported alertness and arousal, whereas effects on pleasure or relaxation were less consistent.

* Intake of tea regularly has a strong impact on psychological function such as work performance and creativity.

The findings suggested that moderate green tea consumption regularly and daily has significant acute benefits in both mood and performance in real-life situations.


Taken all together, there is no doubt that green tea containing numbers of highly bioactive compounds such as caffeine, l-theanine, and epigallocatechin gallate may be considered a functional food to protect the brain functioning against the onset of mood disorders.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea effects on cognition, mood and human brain function: A systematic review by Mancini E1, Beglinger C2, Drewe J2, Zanchi D1, Lang UE1, Borgwardt S3(PubMed)
(2) Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis by Camfield DA1, Stough C, Farrimond J, Scholey AB(PubMed)
(3) Acute effects of tea consumption on attention and mood by Einöther SJ1, Martens VE. (PubMed)

Tuesday, February 12, 2019

Green Tea and its Bioactive Polyphenols Suppress the Onset and Progression of Osteoporosis, Medline Studies Find

Green tea may have a therapeutic and positive effect in reducing the onset, progression, and treatment of osteoporosis, some scientists suggested.

Osteoporosis is a chronic condition characterized by progression in the reduction of bone mass and deterioration of bone tissue and considered a major health problem in both elderly men and women.

The diseases also affect all bone in the body, including the bones of the spine, hip, and wrist

Scientists as of today do not know the exact causes of osteoporosis. However, they do know that certain factors are associated with the onset and progression of the disease.

Osteoporosis is the common disease among the elderly, probably due to the aging effect that induces nutrition deficiency such as
* Vitamin D insufficiency and reduced calcium absorption,

* Reduced hormone production, the drop of estrogen levels after menopause, can speeds up bone loss.

* Reduced production of bone mass and increased bone reabsorption.

These results suggested that osteoporosis can make bone more fragile and easier to break. In elderly, osteoporosis can be dangerous, as fractures can cause prolonged immobility, and required a longer healing process.

Some researchers suggested that fractures in the older population are the most common cause of blood clots or pneumonia, both of which can have fatal consequences.


Long-term use of certain medicines, such as anti-seizure drug Glucocorticoids and medical conditions such as kidney disease, Cushing's syndrome, and an overactive thyroid or parathyroid, can also increase the risk of osteoporosis.


Dr. Stephen P Tuck, the lead author in the study Osteoporosis in men said, "The incidence of osteoporotic fractures in elderly men, just as in aged women, increases exponentially with age; the rise in men, however, is some 5–10 years later than in women. Up to 50% of male osteoporosis have no identifiable etiology; however elderly males have a much higher likelihood of having an identifiable secondary cause than younger men".

Truly, both male and female share the same conditions of the onset of osteoporosis, but the onset of the disease in men is about 10 years later, compared to a woman in the same age.

Interestingly, in the observation of hip fracture in the aging population, Dr. Eric Orwoll, a physician-researcher who studies osteoporosis at Oregon Health and Science University wrote, “A third of all hip fractures occur in men, yet the problem of osteoporosis in men is frequently downplayed or ignored.”

Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world.

In the study to evaluate the effects of ingestion of green tea and green tea bioactive compounds in mitigating bone loss and risk of osteoporotic fractures in both elderly women and men, researchers found that the applications exert significant activities in reducing the onset of osteoporosis, through their antioxidants and initiation of the production of natural antioxidant in the body such as glutathione and enzymes (e.g., catalase and superoxide dismutase) in inhibiting the levels of ROS that facilitate the chain reaction.

Truly, the overexpression of free radicals has been associated with the change in the balance between activities of osteoblasts and osteoclasts, leading to osteoclasts in destroying the calcified tissue and inducing bone remodeling.

These results demonstrated that green tea and its bioactive components exhibit a significant decrease in the risk of fracture by improving bone mineral density and preventing free radicals in damage the bone-forming osteoblasts while suppressing osteoclastic activities.

Moreover, in the review of the effect of green tea and its bioactive components on bone health, researchers indicated that the ingestions display an impressive osteoprotective impact on bone mass and microarchitecture in various bone loss models associated with aging, sex hormone deficiency, and chronic inflammation.

The implication of reduced onset and progression of osteoporosis in the aging population due to sex hormone deficiency may be attributed to green tea and its bioactive compound in increasing the levels of osteocalcin, a bone formation marker, decreasing serum of tartrate-resistant acid phosphatase (TRAP), a bone resorption marker and improving the body in the absorption of calcium.

In fact, the serum levels of osteocalcin (OC) and tartrate-resistant acid phosphatase (TRAP) are considered effective measurements in the rate of bone turn over in patients with osteoporosis.

Interestingly, application of green tea and its bioactive compound also is found to modulate the expression of proinflammatory cytokines in the regulation of osteoblasts and osteoclasts, through inhibiting the production of C-reactive protein (CRP) in the liver in initiating inflammation and reducing levels of interleukin-1 and 6(IL-1-6) and tumor necrosis factor-alpha (TNF-α), the sensitive markers of systemic inflammation.

These differentiation were supported by the study in the evaluation of the efficacy of green tea polyphenols (GTPs) at mitigating bone loss and microstructure deterioration along with related mechanisms in 40 androgen-deficient aged male rats, a model of male osteoporosis, randomly assigned to received A 2 (sham vs. orchidectomy) × 2 (no GTP and 0.5% GTP in drinking water) for 16 weeks.

At the end of experiment, researchers found that rats treated with GTP demonstrate an increased serum osteocalcin concentrations, bone mineral density, and trabecular volume, number, and strength of femur; trabecular volume and thickness and bone formation in both the proximal tibia and periosteal tibial shaft, and decreased eroded surface in the proximal tibia and endocortical tibial shaft; and increased liver glutathione peroxidase activity.

The findings indicated a strong implication of green tea polyphenols in decreasing cortical and trabecular bone loss and increasing both bone density by stimulating the overexpression of bone formation and reducing bone resorption via antioxidant capacity.

Taken together, green tea and its bioactive polyphenols may be considered functional foods in ameliorating early onset, progression and combined with standard medicine for treatment of osteoporosis.

However, intake of green tea supplement should be taken with extreme care due to recent reports of acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Green tea and bone metabolism by Shen CL1, Yeh JK, Cao JJ, Wang JS. (PubMed)
(2) Green tea and bone health: Evidence from laboratory studies by Shen CL1, Yeh JK, Cao JJ, Chyu MC, Wang JS. (PubMed)
(3) Supplementation with green tea polyphenols improves bone microstructure and quality in aged, orchidectomized rats by Shen CL1, Cao JJ, Dagda RY, Tenner TE Jr, Chyu MC, Yeh JK. (PubMed)
(4) Osteoporosis in the aging male: Treatment option by Stephen P Tuck1 and Harish K Datta. (PubMed)

Monday, February 11, 2019

Garlic, The Kitchen Spice in the Prevention and Treatment of Hypertension, Scientists Recommend

Scientists may have found a common kitchen spice with potential in reducing high blood pressure quickly without including any side effects, some studies endorsed.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

High blood pressure means raising the pressure in your heart. If it stays high over time it can damage the body in many ways.

The causes of hypertension are unknown. However, researchers do know that acute hypertension is induced by daily stress.

Certain risk factors such as unhealthy lifestyle choices, physical inactivity unhealthy diet with high in saturated and trans fat, refined products, processed food, high sugar, and salt intake,...... over time cause your blood pressure to spice-up chronically.

Lifestyle choices can also lead to overweight or obese, the risk factors for the early onset of hypertension.

According to the statistic, in the US, over 75 million adults or 32% have high blood pressure.


In other words, 1 in every 3 American adults has the syndrome. Sadly 44% of the mentioned adults with high blood pressure are not under control.


Uncontrol high blood pressure has long been known as a major risk factor for the development of heart disease and stroke, the leading causes of death in the United States.

Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as gastrointestinal discomforts, tiredness, weakness, headache.

Some patients who are taking the hypertensive medicine over the prolonged periods of time may experience symptoms of erectile dysfunction.

In severe cases, intake of antihypertensive drugs for a long term can cause dermatitis, arthritis and anemia and lupus erythematosus-like syndrome, according to the article "Adverse Effects of Antihypertensive Drugs" written by Dr. DWARD D. FREIS, M.D.

If you are currently taking any anti-high blood pressure medications, please make you that you know all the side effects.

Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.

The kitchen spice has been used popularly in traditional and Chinese medicine in treating common cold and flu, blood pressure cholesterol levels, natural antibiotic, etc.

In adult men and women, participated in the Tehran Lipid and Glucose Study (2006-2008 to 2012-2014), intake of garlic is associated to reduce the risk of hypertension by up 26%.

In hypertension of 80-90% patients with excess glucocorticoid level, allicin found in garlic attenuated dexamethasone-induced anorexia and loss of total body weight.

A randomized, placebo-controlled, clinical trial conducted on 56 CVD patients, aged 25 - 75 years old also suggested treatment with garlic-based drugs can be effective for controlling BP in CVD patients and has no interaction with other drugs that CAD patients take, after 3 months of the administration.

Dr. Takashima M the lead author at the Wakunaga Pharmaceutical Co. Ltd said, " aged garlic extract (AGE) is effective in reducing the blood pressure of hypertensive patients,......AGE-induced the concentration-dependent vasorelaxation of isolated rat aortic rings that had been precontracted with norepinephrine"

In fact, The traditional Chinese medicine, food therapy, and hypertension control, all recommended that garlic is of the food to be used for hypertension control, according to a statistical analysis of antihypertensive foods recommended in 20 books on the application of food therapy for hypertension control.

If you can control your diet, make changes to lifestyle, maintaining an ideal weight, you could do just fine without the drugs,

Taking all together, garlic may be used as preventive and controlling effects for patients with or without high blood pressure. Some researchers insisted that garlic anti hypertension effect may result from its anticoagulant property.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats by Dubey H1,2, Singh A1, Patole AM2, Tenpe CR2(PubMed)
(2) Allium vegetable intakes and the incidence of cardiovascular disease, hypertension, chronic kidney disease, and type 2 diabetes in adults: a longitudinal follow-up study by Bahadoran Z1, Mirmiran P, Momenan AA, Azizi F.(PubMed)
(3) Does Garlic Supplementation Control Blood Pressure in Patients with Severe Coronary Artery Disease? A Clinical Trial Study by Mahdavi-Roshan M1, Nasrollahzadeh J1, Mohammad Zadeh A2, Zahedmehr A3. (PubMed)
(4) Traditional Chinese Medicine, Food Therapy, and Hypertension Control: A Narrative Review of Chinese Literature by Zou P1(PubMed)
(5) The anticoagulant rivaroxaban lowers portal hypertension in cirrhotic rats mainly by deactivating hepatic stellate cells by Vilaseca M1,2, García-Calderó H1,3, Lafoz E1,2, García-Irigoyen O3,4, Avila MA3,4, Reverter JC5, Bosch J1,2,3,6, Hernández-Gea V1,3, Gracia-Sancho J1,2,3, García-Pagán JC1,2,3(PubMed)

Saturday, February 9, 2019

Eggplant, The Veggie Which Normalizes the Blood Cholesterol with No Side Effects

Eggplant may process a significant effect in decreasing the risk and onset of abnormally high blood cholesterol, some scientists suggested

Cholesterol, the waxy substance produced by the liver or intake from the dietary sources plays an important role in the building of the cell walls, producing steroid hormones and promoting the digestive function in food digestion.

However, high levels of blood cholesterol can weaken the arterial wall and block the blood flow in the arteries, leading to the substantially increased the risk of heart diseases and stroke.

The ratio of total cholesterol is 4/1, any numbers that are less than is considered within the healthy range. The lower of the ratio is an indication that you have a higher than normal amount of high-density lipoprotein (HDL), which is essential to remove blood cholesterol from the blood back to the liver, leading to less low-density lipoprotein (LDL) in the initiation of cardiovascular diseases.
.

The below table Classification of cholesterol levels, provided by Dr.Michael Tanner and Dr. Nate Link the lead author at the New York University School of Medicine and Bellevue Hospital Center New York,


Cholesterol, mmol/L (mg/dL)ClassificationTotal
<5.17 (<200) Desirable
5.17-6.19 (200-239) Borderline
≥6.20 (≥240) High
HDL-C Classification
<1.00 (<40) Low
≥1.43 (≥60) High


US prevalence (%) of high total cholesterol levels (≥6.21 mmol/L [≥240 mg/dL]) and coronary artery disease (NHANES III: 1988-1991)1


Age, yrHigh cholesterol levelCoronary artery disease
MenWomenMenWomen20-34 9 8 2 3
35-44 18 11 3 4
45-54 25 23 9 6
55-64 25 37 17 12
65-74 22 39 17 11
≥75 14 32 23 16



Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.

The plant has been cultivated in southern and eastern Asia since prehistory. It is famous for its deep purple and the best eggplant can be found from August through October when it is in season.

Chemical constituents of eggplant include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.



In the study to reaffirm the Eggplant (Solanum melongena) consumed extensively in Brazil may have a strong effect in reducing the serum cholesterol researchers at the Instituto de Ciências Biológicas conducted an evaluation to test the plant cholesterol metabolism and hypocholesterolemic effect

In the total of 38 hypercholesterolemic human volunteers ingesting S. melongena infusion for five weeks, 38 hypercholesterolemic subjects were given either S. melongena infusion (N = 19) or placebo (N = 19) participated in two clinical experiments in which the effect of S. melongena infusion was studied with (N = 16) or without (N = 38) dietary orientation.

S. melongena infusion significantly reduced the blood levels of total and LDL cholesterol and of apolipoprotein B.

After dietary orientation, no intra- or intergroup differences were seen for any of the parameters analyzed.

The results suggest that S. melongena infusion had a modest and transitory effect, which was not different from that obtained with standard orientation for dyslipidemia patients (diet and physical activities).


Dried powdered fruits of eggplant (Solanum melongena) was tested in a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20).

Each volunteer received two capsules containing SM (450 mg) or placebo (450 mg) twice daily and was followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil.

After 3 months, serum total cholesterol, LDL-c, and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM.

Dr. Silva GE, the lead author wrote at the final report of the study, " SM, at least in the form commercialized in Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia".


Taken altogether, eggplant may be considered a functional food for the prevention and adjunct therapy for the treatment of high blood cholesterol with no side effects.


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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension by Kwon YI1, Apostolidis E, Shetty K.(PubMed)
(2) Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects by Guimarães PR1, Galvão AM, Batista CM, Azevedo GS, Oliveira RD, Lamounier RP, Freire N, Barros AM, Sakurai E, Oliveira JP, Vieira EC, Alvarez-Leite JI.(PubMed)
(3) [Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients].[Article in Portuguese] by Silva GE1, Takahashi MH, Eik Filho W, Albino CC, Tasim GE, Serri Lde A, Assef AH, Cortez DA, Bazotte RB.(PubMed)
(4) Hyperlipidemia: Part 1. Evaluation and dietary management by Michael Tanner1 and Nate Link.(PMC)