Scientists may have found a herbal plant which processes a strong potential for the treatment of cancer without inducing any side effects, some studies suggested.
Cancers are a class of diseases associated with the irregular and disorder cell growth in the tissue or organs in the body due to the alternation of cell DNA.
Most cases of cancer start in the cells on the surface of the inner lining of the tissue and organ tissue. However, as the cancer proliferation, they can penetrate into the deeper layers of the tissue or organ.
At the advanced stage, the primary cancer site can travel a distance away from the primary site to infect other healthy tissue and organ through fluids and blood circulation.
The exact causes of cancer are unknown. According to the epidemiological studies, the most common risk factors associated with the early onset of the diseases are smoking and tobacco, diet, physical inactivity, long-term exposure to the.sun and radiation and a certain type of virus and bacteria.
Out of all the risk factors that increase the cancer risk, physical activity is one of the factors which has not been under intensified study by the science community.
In the study to examine the accumulate on the benefits of physical activity in relation to cancer risk, progression, and mortality, researchers suggested
* Sedentary behavior may independently affect cancer risk
* The associations with physical activity, including cancer risk factors existed for precancerous lesions.
Although researchers know that physical activity is an important issue associated with the onset of cancer, they do not know the subgroup risk defined by body size, age or sex and tumors subgroups defined by the organ location, receptor status, or molecular subtype.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae.
The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
In the reaffirming the traditional use of chamomile for the treatment of chronic ailments, researchers examine the anticancer properties of aqueous and methanolic extracts of chamomile against various human cancer cell lines.
Chamomile extracts a significant decrease in cell viability in various human cancer cell lines without inducing herm to the healthy cells.
Injection of the herbal extract causes the apoptosis of cancer cells, causing herm to the normal cells.
The anti cancers effect of chamomile extract was attributed to the bioactive compound apigenin 7-O-glucoside, the major constituent of chamomile; some minor glycoside components.
These results reconfirm the use of chamomile extract in the treatment of cancers in traditional medicine.
Furthermore, the study to compare the anticancer activity of phenolic profile of six herbal infusions namely Cretan marjoram, pink savory, oregano, mountain tea, pennyroyal and chamomile by LCDAD-MS and by GC-MS, suggested
* All herbal infusions exhibit antiradical activity correlated positively with total phenolic content
* All infusions exhibit the potential to inhibit cell proliferation and to reduce IL-8 levels in HT29 colon and PC3 prostate cancer cells.
* The efficacy of all herbal medicines in inhibition of cancer cell line was attributed to the activation of the proteins associated with the cell death programming and production of the inflammatory cytokine.
Interestingly, in the comparison the cancer property of 20 essential oil from herbal plants, Dr. Mitoshi M, the lead scientists indicated, EOs from the herbal plants showed patterns of inhibition of DNA replicative property, similar to their cancer cell growth inhibitory activity, and their inhibitory activity and EOs from chamomile (Matricaria chamomilla L.) showed significant effects on both cancer cell growth and mast cell degranulation.
Taken altogether, chamomile extract, essential oil may be used with no side effects for the prevention and combined with the primary medicine for the treatment of cancers.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.
Srivastava JK1, Gupta S.(PubMed)
(2) Herbal infusions; their phenolic profile, antioxidant and anti-inflammatory effects in HT29 and PC3 cells by Kogiannou DA1, Kalogeropoulos N, Kefalas P, Polissiou MG, Kaliora AC. (PubMed)
(3) Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities by Mitoshi M1, Kuriyama I, Nakayama H, Miyazato H, Sugimoto K, Kobayashi Y, Jippo T, Kanazawa K, Yoshida H, Mizushina Y. (PubMed)
(4) Physical Activity and Cancer by Jessica Clague and Leslie Bernstein. (PMC)
Wednesday, March 13, 2019
Ginger, the Potent anti Metabolic Syndrome Pungent Spice, Scientists Say
Ginger may have a potential and profound effect in regulating the expression of metabolic syndrome, some scientists suggested.
Metabolic syndrome is a cluster of conditions associated with the onset of cardiovascular disease and diabetes, including fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
Researchers suggested that people who have 3 of 5 above conditions are at substantial risk of heart disease, stroke, and type 2 diabetes.
There is no single cause of metabolic syndrome. some conditions epidemiologically are associated with overweight or obese, insulin resistance, inactive lifestyle and poor diet.
According to the statistic, In the US, approximately, over 23 percent of adults have metabolic syndrome, many of them do not know they have it.
In fact, metabolic syndrome can be reversed through a healthy lifestyle choice, accompanied by weight loss.
Dr. Christos Pitsavos, the cardio team at the University of Athens and Society for Biomedical Diabetes Research, wrote, "Several epidemiologic studies and some clinical trials, it has been suggested that people with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle."
"During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products".
These results clearly stated that by changing the poor diet pattern to a healthy one accompanied with moderate exercise, metabolic syndrome can be reserved.
Furthermore, a healthy lifestyle in patients with metabolic syndrome also greatly improved the reduction of body weight.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the treatment of metabolic syndrome, researchers assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS) by searching the database of medical literature.
10 studies met the inclusion criteria with a total of 490 individuals were included in the review.
Ginger showed a significant beneficial effect on glucose control and insulin sensitivity.
Ginger significantly reduced fasting blood glucose in T2DM patients (-21.24; 95% CI: -33.21, -9.26; P < 0.001) and three-month average plasma glucose concentration.
Futhermore, ginger also displayed significant effects of improvement of lipid profile.
Dr. Zhu J, the lead scientist said, at the final report "Based on the negligible side effects and obvious ameliorative effects on glucose control, insulin sensitivity, and lipid profile, ginger may be a promising adjuvant therapy for T2DM and MetS".
Moreover, in order to gain more evidence of ginger anti-metabolic syndrome effect, a study to determine the individual and concomitant effect of 6-weeks water-based exercise and oral ginger supplement on markers that have related to metabolic syndrome and systemic inflammation in obese women with breast neoplasms was conducted the University of Mazandaran.
40 women diagnosed with breast neoplasms were randomly assigned into four groups; placebo, exercise training, ginger supplement, and exercise training+ ginger supplement groups.
Participants in the ginger supplement group and the exercise training+ ginger supplement group have orally received 4 capsules, 7 days a week and for 6 weeks.
During the experiment, the ginger supplementation and the water-based exercise have resulted in a reduction of hs-CRP, IL-10 (inflammation), insulin, glucose, insulin resistance, low-density lipoprotein (LDL), triglyceride (TG); but an increase in high-density lipoprotein (HDL) and ratio HDL/LDL.
These results strongly suggested that ginger supplement plus exercise demonstrates a significant effect in reducing the fasting glucose, insulin resistance, inflammation, and lipid profile and balanced the ratio of high and low-density lipoproteins.
In other words, the water-based exercise and ginger supplement group significantly showed a larger positive effect on all outcomes, compared to the water-based exercise or ginger supplement alone groups.
The findings suggested that obese breast neoplasms survivors metabolic syndrome and elevated inflammation were totally inhibited by the application of ginger supplement plus exercise training.
Taken altogether, ginger, the pungent spice can be considered a functional food for the prevention and treatment of metabolic syndrome accompanied by moderate exercise without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhu J1, Chen H1, Song Z1, Wang X1, Sun Z2. (PubMed)
(2) Individually and Combined Water-Based Exercise With Ginger Supplement, on Systemic Inflammation and Metabolic Syndrome Indices, Among the Obese Women With Breast Neoplasms by Karimi N1, Dabidi Roshan V1, Fathi Bayatiyani Z1. (PubMed)
(3) Diet, Exercise and Metabolic Syndrome by Christos Pitsavos,1 Demosthenes Panagiotakos,2 Michael Weinem,3 and Christodoulos Stefanadis. (PMC)
Metabolic syndrome is a cluster of conditions associated with the onset of cardiovascular disease and diabetes, including fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
Researchers suggested that people who have 3 of 5 above conditions are at substantial risk of heart disease, stroke, and type 2 diabetes.
There is no single cause of metabolic syndrome. some conditions epidemiologically are associated with overweight or obese, insulin resistance, inactive lifestyle and poor diet.
According to the statistic, In the US, approximately, over 23 percent of adults have metabolic syndrome, many of them do not know they have it.
In fact, metabolic syndrome can be reversed through a healthy lifestyle choice, accompanied by weight loss.
Dr. Christos Pitsavos, the cardio team at the University of Athens and Society for Biomedical Diabetes Research, wrote, "Several epidemiologic studies and some clinical trials, it has been suggested that people with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle."
"During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products".
These results clearly stated that by changing the poor diet pattern to a healthy one accompanied with moderate exercise, metabolic syndrome can be reserved.
Furthermore, a healthy lifestyle in patients with metabolic syndrome also greatly improved the reduction of body weight.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the treatment of metabolic syndrome, researchers assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS) by searching the database of medical literature.
10 studies met the inclusion criteria with a total of 490 individuals were included in the review.
Ginger showed a significant beneficial effect on glucose control and insulin sensitivity.
Ginger significantly reduced fasting blood glucose in T2DM patients (-21.24; 95% CI: -33.21, -9.26; P < 0.001) and three-month average plasma glucose concentration.
Futhermore, ginger also displayed significant effects of improvement of lipid profile.
Dr. Zhu J, the lead scientist said, at the final report "Based on the negligible side effects and obvious ameliorative effects on glucose control, insulin sensitivity, and lipid profile, ginger may be a promising adjuvant therapy for T2DM and MetS".
Moreover, in order to gain more evidence of ginger anti-metabolic syndrome effect, a study to determine the individual and concomitant effect of 6-weeks water-based exercise and oral ginger supplement on markers that have related to metabolic syndrome and systemic inflammation in obese women with breast neoplasms was conducted the University of Mazandaran.
40 women diagnosed with breast neoplasms were randomly assigned into four groups; placebo, exercise training, ginger supplement, and exercise training+ ginger supplement groups.
Participants in the ginger supplement group and the exercise training+ ginger supplement group have orally received 4 capsules, 7 days a week and for 6 weeks.
During the experiment, the ginger supplementation and the water-based exercise have resulted in a reduction of hs-CRP, IL-10 (inflammation), insulin, glucose, insulin resistance, low-density lipoprotein (LDL), triglyceride (TG); but an increase in high-density lipoprotein (HDL) and ratio HDL/LDL.
These results strongly suggested that ginger supplement plus exercise demonstrates a significant effect in reducing the fasting glucose, insulin resistance, inflammation, and lipid profile and balanced the ratio of high and low-density lipoproteins.
In other words, the water-based exercise and ginger supplement group significantly showed a larger positive effect on all outcomes, compared to the water-based exercise or ginger supplement alone groups.
The findings suggested that obese breast neoplasms survivors metabolic syndrome and elevated inflammation were totally inhibited by the application of ginger supplement plus exercise training.
Taken altogether, ginger, the pungent spice can be considered a functional food for the prevention and treatment of metabolic syndrome accompanied by moderate exercise without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhu J1, Chen H1, Song Z1, Wang X1, Sun Z2. (PubMed)
(2) Individually and Combined Water-Based Exercise With Ginger Supplement, on Systemic Inflammation and Metabolic Syndrome Indices, Among the Obese Women With Breast Neoplasms by Karimi N1, Dabidi Roshan V1, Fathi Bayatiyani Z1. (PubMed)
(3) Diet, Exercise and Metabolic Syndrome by Christos Pitsavos,1 Demosthenes Panagiotakos,2 Michael Weinem,3 and Christodoulos Stefanadis. (PMC)
Tuesday, March 12, 2019
Chaste tree berry (Vitex agnus-castus), the Functional Herb for the Prevention and Treatment of on Hyperprolactinemia with No Side Effects
Hyperprolinaemia is a condition characterized by overexpression of the level of prolactin in the blood produced by the lactotroph cells of the anterior pituitary gland.
Normally, the expression of hormone prolactin is to enhance breast development during pregnancy and to induce lactation.
In non-pregnant women, elevated levels of prolactin can disrupt the normal menstrual period in women, causing the complication of infertility, abnormal lactation, amenorrhea, irregular periods, breast pain and painful sexual intercourse.
Most common caused of the onset of hyperlactatemia is the result of the growth of a tumor on the pituitary gland. Most cases of the pituitary gland are noninvasive, however, if the tumor is growing large enough, it can suppress the nearby nerve cells, causing headache and vision problems.
Some researchers suggested the syndrome can also be caused by long-term use of certain medication.
Dr. Daria La Torre, the lead author in the study "Pharmacological causes of hyperprolactinemia" said, "Several drugs may determine a significant increase in prolactin serum concentration that is frequently associated with symptoms. The so-called typical antipsychotics are frequently responsible for drug-related hyperprolactinemia"
And, "Risperidone is one of the atypical neuroleptics most likely to induce hyperprolactinemia, while other atypical drugs are infrequently and only transiently associated with increase of prolactin levels" and "Antidepressant drugs with serotoninergic activity, including selective serotonin reuptake inhibitors (SSRI), monoamine oxidase inhibitors (MAO-I) and some tricyclics, can cause hyperprolactinemia.".
Therefore, if you are taking the above medication, please make sure you discuss the problem with your doctor.
In fact, some women experience the syndrome of hyperprolactinemia with unknown causes.
Most common conventional treatment target the symptoms and reducing the size of the tumor. The unknown causes of hyperprolactinemia are treated with synthetic thyroid hormone.
Medication used for the treatment of hyperprolactinemia including Medical treatment of dopamine agonists (DA): bromocriptine, lisuride, quinagolide, and cabergoline. And in over 80% of cases, these drugs induce normal prolactinemia and ovulatory cycles.
If you are taking one of these medications for the treatment of hyperprolactinemia, please make you know all the side effects
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region,.
The plant has been used in herbal medicine for thousands of year as an anaphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts by taking it in a prolonged period of time.
There was a report that chaste tree berry stems and leaves used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria.
With an aim to reaffirming the traditional use of Vitex agnus-castus L. (chaste tree; chaste berry for the treatment of a range of female reproductive conditions in Anglo-American and European practice, researchers at the Royal Melbourne Institute of Technology-University conducted an experiment to examine the effect of the herbal medicine in women with premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinaemia.
In the search based on the Cochrane risk of bias and Jadad scales on the database of medical literature identifies 13 Thirteen randomized, controlled trials and twelve are included in this review, of which eight investigated premenstrual syndrome, two premenstrual dysphoric disorder, and two latent hyperprolactinemia.
Application of the Vitex agnus-castus in latent hyperprolactinemia suggested that the herbal medicine is superior compared to placebo for reducing TRH-stimulated prolactin secretion, normalizing a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels.
And Vitex comparable to bromocriptine for reducing serum prolactin levels and ameliorating cyclic mastalgia. Adverse events with Vitex were mild and generally infrequent.
These results indicated, Vitex extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
Furthermore, Dr, Milewicz A, in the finding natural medicine with no side effect in the treatment of hyperprolactinemia conducted a randomized double-blind study vs. placebo to evaluate the efficacy of a Vitex agnus castus preparation (Strotan capsules) vs. placebo.
The clinical study involved 52 women with luteal phase defects due to latent hyperprolactinemia.
The participants were given a daily dose of one capsule (20 mg) Vitex agnus castus preparation and placebo.
In the assessment of the blood for hormonal analysis taken at days 5-8 and day 20 of the menstrual cycle before and after three months of therapy.
Women who were received the Vitex agnus castus preparation showed a reduction of prolactin release after 3 months.
The shortened luteal phases of these women were normalized and deficits in the luteal progesterone synthesis were eliminated.
These changes were significant and occurred only in the Vitex group.
Side effects were not seen during the experiment and two women treated with the Vitex agnus castus preparation got pregnant.
Taken altogether, Chaste tree berry (Vitex agnus-castus) may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of hyperprolactinemia
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study].[Article in German] by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) Pharmacological causes of hyperprolactinemia by bDaria La Torre and Alberto Falorni. (PMC)
Normally, the expression of hormone prolactin is to enhance breast development during pregnancy and to induce lactation.
In non-pregnant women, elevated levels of prolactin can disrupt the normal menstrual period in women, causing the complication of infertility, abnormal lactation, amenorrhea, irregular periods, breast pain and painful sexual intercourse.
Most common caused of the onset of hyperlactatemia is the result of the growth of a tumor on the pituitary gland. Most cases of the pituitary gland are noninvasive, however, if the tumor is growing large enough, it can suppress the nearby nerve cells, causing headache and vision problems.
Some researchers suggested the syndrome can also be caused by long-term use of certain medication.
Dr. Daria La Torre, the lead author in the study "Pharmacological causes of hyperprolactinemia" said, "Several drugs may determine a significant increase in prolactin serum concentration that is frequently associated with symptoms. The so-called typical antipsychotics are frequently responsible for drug-related hyperprolactinemia"
And, "Risperidone is one of the atypical neuroleptics most likely to induce hyperprolactinemia, while other atypical drugs are infrequently and only transiently associated with increase of prolactin levels" and "Antidepressant drugs with serotoninergic activity, including selective serotonin reuptake inhibitors (SSRI), monoamine oxidase inhibitors (MAO-I) and some tricyclics, can cause hyperprolactinemia.".
Therefore, if you are taking the above medication, please make sure you discuss the problem with your doctor.
In fact, some women experience the syndrome of hyperprolactinemia with unknown causes.
Most common conventional treatment target the symptoms and reducing the size of the tumor. The unknown causes of hyperprolactinemia are treated with synthetic thyroid hormone.
Medication used for the treatment of hyperprolactinemia including Medical treatment of dopamine agonists (DA): bromocriptine, lisuride, quinagolide, and cabergoline. And in over 80% of cases, these drugs induce normal prolactinemia and ovulatory cycles.
If you are taking one of these medications for the treatment of hyperprolactinemia, please make you know all the side effects
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region,.
The plant has been used in herbal medicine for thousands of year as an anaphrodisiac herb and considered a Queen herb in treating menstrual problems and discomforts by taking it in a prolonged period of time.
There was a report that chaste tree berry stems and leaves used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria.
With an aim to reaffirming the traditional use of Vitex agnus-castus L. (chaste tree; chaste berry for the treatment of a range of female reproductive conditions in Anglo-American and European practice, researchers at the Royal Melbourne Institute of Technology-University conducted an experiment to examine the effect of the herbal medicine in women with premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinaemia.
In the search based on the Cochrane risk of bias and Jadad scales on the database of medical literature identifies 13 Thirteen randomized, controlled trials and twelve are included in this review, of which eight investigated premenstrual syndrome, two premenstrual dysphoric disorder, and two latent hyperprolactinemia.
Application of the Vitex agnus-castus in latent hyperprolactinemia suggested that the herbal medicine is superior compared to placebo for reducing TRH-stimulated prolactin secretion, normalizing a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels.
And Vitex comparable to bromocriptine for reducing serum prolactin levels and ameliorating cyclic mastalgia. Adverse events with Vitex were mild and generally infrequent.
These results indicated, Vitex extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
Furthermore, Dr, Milewicz A, in the finding natural medicine with no side effect in the treatment of hyperprolactinemia conducted a randomized double-blind study vs. placebo to evaluate the efficacy of a Vitex agnus castus preparation (Strotan capsules) vs. placebo.
The clinical study involved 52 women with luteal phase defects due to latent hyperprolactinemia.
The participants were given a daily dose of one capsule (20 mg) Vitex agnus castus preparation and placebo.
In the assessment of the blood for hormonal analysis taken at days 5-8 and day 20 of the menstrual cycle before and after three months of therapy.
Women who were received the Vitex agnus castus preparation showed a reduction of prolactin release after 3 months.
The shortened luteal phases of these women were normalized and deficits in the luteal progesterone synthesis were eliminated.
These changes were significant and occurred only in the Vitex group.
Side effects were not seen during the experiment and two women treated with the Vitex agnus castus preparation got pregnant.
Taken altogether, Chaste tree berry (Vitex agnus-castus) may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of hyperprolactinemia
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study].[Article in German] by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) Pharmacological causes of hyperprolactinemia by bDaria La Torre and Alberto Falorni. (PMC)
Ginger, Relieves Pain and Reduced Disability of Patients with Osteoarthritis
Ginger may have a potential and positive effect in ameliorating the symptoms of pain and complication of reduced quality of life in patients with osteoarthritis, some scientists suggested.
Osteoarthritis (OA) is a chronic condition of a type of joint disease characterized by the breaking down of joint cartilage and underlying bone due to “wear and tear” of joints over time.
Some researchers suggested that OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, affecting the joint structure and progressive deterioration of cartilage.
According to the statistic from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% in men and 13% in women.
Epidemiological strongly suggested that obese and overweight which have a strong impact on the weight-bearing joints, genetic preposition of a patient can make such patient more susceptible to the disease compared to others do not, people with a joint injury that did heal properly in the younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting or other movements and the increase in age are associated to the increased risk of the onset of the disease.
The most common symptoms of osteoarthritis are joint pain and stiffness.
Dr. Giuseppe Musumeci, the lead author in the study "Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression" suggested that besides the risk factors mentioned above, dietary factors also play an important role for the onset of the disease.
In the dietary aspect in the induction of OA, the research team wrote, "This diet (The Western diet) is mainly constituted by preservative and harmful substances, such as animal fat and glucose excessive concentration and lack of nutritional factors, such as vitamins and nutrient minerals essential for our body. Moreover, the bad dietary habits may predispose people to obesity, which is responsible for both metabolic destroying processes affecting the cartilage and overload of the joints, especially hips and knees".
And, " quantity and quality of nutrient intake. Low intake of vitamin D and vitamin C is a possible risk factor for knee OA, while certain food groups, such as milk and dairy products, meat and poultry are beneficial for knee OA. Thus we could affirm that nutritional imbalance, combined with endocrine abnormalities, may be involved in the pathogenesis of OA".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to reaffirm the traditional use of ginger for the treatment of osteoarthritis, a joint review led by the Copenhagen University Hospital, Bispebjerg and Frederiksberg was conducted to assess the clinical efficacy and safety of oral ginger for the symptomatic treatment of osteoarthritis (OA).
The study was carried out by searching the randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged >18 years satisfied the predetermined guidelines and criteria, including the outcomes of the reduction in pain and disability.
Out of 122 retrieved references, 117 were discarded, only 5 five trials (593 patients) were selected for meta-analyses.
All 5 remained studies suggested that ginger intake scored a statistically significant pain reduction.
Furthermore, application of ginger in subjects with osteoarthritis demonstrates a statistically significant reduction in disability compared to control.
However, according to the returned questionnaires from the participants, researchers surprisingly found that patients given ginger are more than twice as likely to discontinue treatment compared to placebo.
Dr. Mozaffari-Khosravi H, the lead author, launched a joint study to determine the ginger powder effects in relieving pain and inflammation in patients with osteoarthritis.
120 participants selected for the randomized double-blind placebo-controlled 3-month clinical trial for knee osteoarthritis were randomly assigned to one of two groups: the ginger group (GG) or the placebo group (PG).
Ginger selected group was given capsules containing 500 mg of ginger powder, while the PG group was given capsules filled with 500 mg starch.
At the baseline, proinflammatory cytokine concentrations did not differ by group, observed by the participant's blood sample.
After 3 months, GG showed a significant reduction of cytokines compared to the PG.
In the final report, the research team wrote, "ginger supplementation may have promising benefits for knee osteoarthritis".
These results reconfirming the use of ginger for the treatment of osteoarthritis in traditional medicine with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials by Bartels EM1, Folmer VN2, Bliddal H2, Altman RD3, Juhl C4, Tarp S2, Zhang W5, Christensen R. (PubMed)
(2) Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial by Mozaffari-Khosravi H1,2, Naderi Z1, Dehghan A3, Nadjarzadeh A1, Fallah Huseini H. (PubMed)
(3) Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression by Giuseppe Musumeci,1,* Flavia Concetta Aiello,1 Marta Anna Szychlinska,1Michelino Di Rosa,2 Paola Castrogiovanni,1 and Ali Mobasheri. (PubMed)
Osteoarthritis (OA) is a chronic condition of a type of joint disease characterized by the breaking down of joint cartilage and underlying bone due to “wear and tear” of joints over time.
Some researchers suggested that OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, affecting the joint structure and progressive deterioration of cartilage.
According to the statistic from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% in men and 13% in women.
Epidemiological strongly suggested that obese and overweight which have a strong impact on the weight-bearing joints, genetic preposition of a patient can make such patient more susceptible to the disease compared to others do not, people with a joint injury that did heal properly in the younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting or other movements and the increase in age are associated to the increased risk of the onset of the disease.
The most common symptoms of osteoarthritis are joint pain and stiffness.
Dr. Giuseppe Musumeci, the lead author in the study "Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression" suggested that besides the risk factors mentioned above, dietary factors also play an important role for the onset of the disease.
In the dietary aspect in the induction of OA, the research team wrote, "This diet (The Western diet) is mainly constituted by preservative and harmful substances, such as animal fat and glucose excessive concentration and lack of nutritional factors, such as vitamins and nutrient minerals essential for our body. Moreover, the bad dietary habits may predispose people to obesity, which is responsible for both metabolic destroying processes affecting the cartilage and overload of the joints, especially hips and knees".
And, " quantity and quality of nutrient intake. Low intake of vitamin D and vitamin C is a possible risk factor for knee OA, while certain food groups, such as milk and dairy products, meat and poultry are beneficial for knee OA. Thus we could affirm that nutritional imbalance, combined with endocrine abnormalities, may be involved in the pathogenesis of OA".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to reaffirm the traditional use of ginger for the treatment of osteoarthritis, a joint review led by the Copenhagen University Hospital, Bispebjerg and Frederiksberg was conducted to assess the clinical efficacy and safety of oral ginger for the symptomatic treatment of osteoarthritis (OA).
The study was carried out by searching the randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged >18 years satisfied the predetermined guidelines and criteria, including the outcomes of the reduction in pain and disability.
Out of 122 retrieved references, 117 were discarded, only 5 five trials (593 patients) were selected for meta-analyses.
All 5 remained studies suggested that ginger intake scored a statistically significant pain reduction.
Furthermore, application of ginger in subjects with osteoarthritis demonstrates a statistically significant reduction in disability compared to control.
However, according to the returned questionnaires from the participants, researchers surprisingly found that patients given ginger are more than twice as likely to discontinue treatment compared to placebo.
Dr. Mozaffari-Khosravi H, the lead author, launched a joint study to determine the ginger powder effects in relieving pain and inflammation in patients with osteoarthritis.
120 participants selected for the randomized double-blind placebo-controlled 3-month clinical trial for knee osteoarthritis were randomly assigned to one of two groups: the ginger group (GG) or the placebo group (PG).
Ginger selected group was given capsules containing 500 mg of ginger powder, while the PG group was given capsules filled with 500 mg starch.
At the baseline, proinflammatory cytokine concentrations did not differ by group, observed by the participant's blood sample.
After 3 months, GG showed a significant reduction of cytokines compared to the PG.
In the final report, the research team wrote, "ginger supplementation may have promising benefits for knee osteoarthritis".
These results reconfirming the use of ginger for the treatment of osteoarthritis in traditional medicine with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials by Bartels EM1, Folmer VN2, Bliddal H2, Altman RD3, Juhl C4, Tarp S2, Zhang W5, Christensen R. (PubMed)
(2) Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial by Mozaffari-Khosravi H1,2, Naderi Z1, Dehghan A3, Nadjarzadeh A1, Fallah Huseini H. (PubMed)
(3) Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression by Giuseppe Musumeci,1,* Flavia Concetta Aiello,1 Marta Anna Szychlinska,1Michelino Di Rosa,2 Paola Castrogiovanni,1 and Ali Mobasheri. (PubMed)
Monday, March 11, 2019
Strawberries, A Potential Anti Benign Prostatic Hyperplasia and Prostate Cancer Functional Food
Scientists may have found a tasty whole fruit for the prevention and treatment of benign prostatic hyperplasia (enlarged prostate) and prostate cancer with no side effects, according to studies.
Benign prostatic hyperplasia happened mostly in the older age population group is a condition of an enlarged prostate that can cause some serious urinary symptoms, such as blocking the flow of urine out of the bladder.
In many cases, an enlarged prostate can also induce bladder, urinary tract or kidney problems and prostate cancer.
Prostate cancer is slow growth and a medical condition characterized by cell growth disorderly and uncontrollably in the prostate tissue.
Most cases of prostate cancer start in the cell on the surface of the inner lining of the prostate gland
At the advanced stage, the cancerous cell can travel a distance away from the prostate to infect other healthy tissue, through blood and fluid circulation.
The causes of prostate cancer are unknown. Epidemiologically, researchers do know that the increase in age, ethnicity, family history, genetic preposition of BRCA1 and/or BRCA2 and agent orange exposure are associated with an increased risk of the disease.
Some researchers suggested that a poor eating habit and lifestyle are the most common risk factors associated with the onset of benign prostatic hyperplasia and prostate cancer. Therefore, by changing to a healthy diet, the risk of benign prostatic hyperplasia and prostate cancer may be preventable.
Dr. Devrim E, in the concern of the widespread of prostate cancer and benign prostatic hyperplasia (BPH), over last few decades said, "garlic and its preparations have been used for the treatment of prostate cancer and relief of BPH symptoms for decades. It is thought that the mechanism(s) through which garlic may show anti-cancer and anti-inflammatory effects".
These results suggested adding garlic into your diet daily can decrease the incidence of both benign prostatic hyperplasia and prostate cancer with no side effects.
Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.
Starting at age 40, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Therefore in order to prevent the symptoms of enlarged prostate is to naturally impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate. Prostate Cancer is defined as a condition of the abnormal proliferation of cells in the prostate.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
With an aim to find the natural compound which processes the potency to inhibit the benign prostatic hyperplasia (BPH), a common disease of the prostate that affects men as they age, and a risk factor for developing prostate cancer with no side effects, researchers at the Monash University looked into the anti BPH activity of lycopene found abundantly in the strawberry by searching the database of medical literature.
Out many medical studies were examined, only 8 published randomized controlled trials (RCTs) comparing lycopene to placebo (or other interventions) for the treatment of BPH and prostate cancer met the inclusion criteria were selected for this systematic review.
Meta-analysis of two studies indicated a decrease in PSA levels in men diagnosed with prostate cancer, who received lycopene compared to placebo.
In a human prostate epithelial cell line (P21) and two tumor cell lines (P21 tumor cell line 1 and 2) derived from the same patient, and a normal human breast epithelial cell line (B42) and a tumor line derived from it (B42 clone 16), researchers examined the cytotoxic effects of strawberry polyphenols.
By applying the polyphenol-rich extract derived from strawberry or anthocyanin or tannin-rich sub-fractions to the cell lines in doses varying from 50 to 1.5 microg/ml, researchers discovered the strawberry extract inhibited over 50% in cell survival of both the normal and the tumor lines with the doses of approximately 5 microg/ml.
The extracts were found to exert cytotoxicity to peripheral blood human lymphocytes with the doses higher levels 20 microg/ml for the similar effect of 50% reduction in cell survival.
Compound analysis assay suggested that the cytotoxicity was retained in the tannin-rich fraction was considerably more toxic to all cells (normal or tumor cell lines or lymphocytes) than the anthocyanin-rich fraction the tannin-rich fraction.
Furthermore, In LNCaP and PC-3) tumor cell lines, strawberry extract with concentrations of 50 microg/ml was required for 50% reduction in cell survival.
The finding suggested that strawberry processed high amounts of bioactive compounds may be considered a functional food for the prevention and treatment of benign prostatic hyperplasia (BPH) and prostate cancer without inducing any side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Lycopene for the prevention and treatment of benign prostatichyperplasia and prostate cancer: a systematic review by Ilic D, Misso M.(PubMed)
(2) Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines by Weaver J, Briscoe T, Hou M, Goodman C, Kata S, Ross H, McDougall G, Stewart D, Riches A.(PubMed)
(3) Lycopene for the prevention of prostate cancer by Ilic D, Forbes KM, Hassed C.(PubMed)
(4) Is garlic a promising food for benign prostatic hyperplasia and prostate cancer? by Devrim E1, Durak I. (PubMed)
Benign prostatic hyperplasia happened mostly in the older age population group is a condition of an enlarged prostate that can cause some serious urinary symptoms, such as blocking the flow of urine out of the bladder.
In many cases, an enlarged prostate can also induce bladder, urinary tract or kidney problems and prostate cancer.
Prostate cancer is slow growth and a medical condition characterized by cell growth disorderly and uncontrollably in the prostate tissue.
Most cases of prostate cancer start in the cell on the surface of the inner lining of the prostate gland
At the advanced stage, the cancerous cell can travel a distance away from the prostate to infect other healthy tissue, through blood and fluid circulation.
The causes of prostate cancer are unknown. Epidemiologically, researchers do know that the increase in age, ethnicity, family history, genetic preposition of BRCA1 and/or BRCA2 and agent orange exposure are associated with an increased risk of the disease.
Some researchers suggested that a poor eating habit and lifestyle are the most common risk factors associated with the onset of benign prostatic hyperplasia and prostate cancer. Therefore, by changing to a healthy diet, the risk of benign prostatic hyperplasia and prostate cancer may be preventable.
Dr. Devrim E, in the concern of the widespread of prostate cancer and benign prostatic hyperplasia (BPH), over last few decades said, "garlic and its preparations have been used for the treatment of prostate cancer and relief of BPH symptoms for decades. It is thought that the mechanism(s) through which garlic may show anti-cancer and anti-inflammatory effects".
These results suggested adding garlic into your diet daily can decrease the incidence of both benign prostatic hyperplasia and prostate cancer with no side effects.
Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.
Starting at age 40, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Therefore in order to prevent the symptoms of enlarged prostate is to naturally impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate. Prostate Cancer is defined as a condition of the abnormal proliferation of cells in the prostate.
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
With an aim to find the natural compound which processes the potency to inhibit the benign prostatic hyperplasia (BPH), a common disease of the prostate that affects men as they age, and a risk factor for developing prostate cancer with no side effects, researchers at the Monash University looked into the anti BPH activity of lycopene found abundantly in the strawberry by searching the database of medical literature.
Out many medical studies were examined, only 8 published randomized controlled trials (RCTs) comparing lycopene to placebo (or other interventions) for the treatment of BPH and prostate cancer met the inclusion criteria were selected for this systematic review.
Meta-analysis of two studies indicated a decrease in PSA levels in men diagnosed with prostate cancer, who received lycopene compared to placebo.
In a human prostate epithelial cell line (P21) and two tumor cell lines (P21 tumor cell line 1 and 2) derived from the same patient, and a normal human breast epithelial cell line (B42) and a tumor line derived from it (B42 clone 16), researchers examined the cytotoxic effects of strawberry polyphenols.
By applying the polyphenol-rich extract derived from strawberry or anthocyanin or tannin-rich sub-fractions to the cell lines in doses varying from 50 to 1.5 microg/ml, researchers discovered the strawberry extract inhibited over 50% in cell survival of both the normal and the tumor lines with the doses of approximately 5 microg/ml.
The extracts were found to exert cytotoxicity to peripheral blood human lymphocytes with the doses higher levels 20 microg/ml for the similar effect of 50% reduction in cell survival.
Compound analysis assay suggested that the cytotoxicity was retained in the tannin-rich fraction was considerably more toxic to all cells (normal or tumor cell lines or lymphocytes) than the anthocyanin-rich fraction the tannin-rich fraction.
Furthermore, In LNCaP and PC-3) tumor cell lines, strawberry extract with concentrations of 50 microg/ml was required for 50% reduction in cell survival.
The finding suggested that strawberry processed high amounts of bioactive compounds may be considered a functional food for the prevention and treatment of benign prostatic hyperplasia (BPH) and prostate cancer without inducing any side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Lycopene for the prevention and treatment of benign prostatichyperplasia and prostate cancer: a systematic review by Ilic D, Misso M.(PubMed)
(2) Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines by Weaver J, Briscoe T, Hou M, Goodman C, Kata S, Ross H, McDougall G, Stewart D, Riches A.(PubMed)
(3) Lycopene for the prevention of prostate cancer by Ilic D, Forbes KM, Hassed C.(PubMed)
(4) Is garlic a promising food for benign prostatic hyperplasia and prostate cancer? by Devrim E1, Durak I. (PubMed)
Manuka Honey, the Best for the Prevention and Treatment of Acute and Chronic Inflammatory Diseases
Honey may the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulates the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the times are won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
On finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at the Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited by proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "the beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the stud, Manuka honey treated group displayed a significantly decreased the ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.
Manuka honey treated group also showed increased levels of antioxidants enzymes which were suppressed by the injection of ethanol to an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker and plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and nonenzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken altogether, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulates the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the times are won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
On finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at the Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited by proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "the beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the stud, Manuka honey treated group displayed a significantly decreased the ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.
Manuka honey treated group also showed increased levels of antioxidants enzymes which were suppressed by the injection of ethanol to an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker and plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and nonenzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken altogether, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
Sunday, March 10, 2019
Chinese Celery, the Prominent Post Stroke Treatment Functional Food
Scientists may have found a whole food for the treatment and improvement of the quality of life of post-stroke patients and without inducing any side effects, according to studies.
Stroke is a medical condition caused by reduced blood flow to the brain, leading to the death of brain cells due to lack of oxygen or bleeding.
In other words, a stroke can either be results of a blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).
A mini-stroke is a temporary disruption of blood flow to the brain that only causes some disruption to the brain with inducing permanent damage.
Depending on the parts of the neuron being damage, patients may experience different symptoms. However, most common symptoms of stroke include paralysis or numbness of the face, arm or leg, problems in vision, speaking, walking and persistent headache.
Certain medical conditions such as diabetes. heart diseases, long-term use of tobacco, the increase in age, ethnicity are some prevalent risk factors of stroke.
Out of many risk factors, people who have hypertension, particularly untreated hypertension and follow the Western diet are at increased risk of the onset of stroke, according to epidemiological studies.
In examining the post-stroke patients, a poor diet pattern with a high in saturated and trans fat, red meat and processed foods have been found in the high percentage, compared to the traditional diet.
Dr. Mehdi Foroughi, the lead scientist in the study of poor diet in risk of stoke wrote, " adherence to the improvements in nutrition and diet can reduce the incidence of stroke. Higher antioxidant, vitamins, potassium, calcium, vegetables, fruits, whole grain intake, and adherence to the Mediterranean diet or DASH diet can lower stroke incidence".
The statement clearly suggested that a healthy diet rich in fruits and vegetable and whole grain and low in red meat, saturated fat and trans fat, and processed food is the best for prevention and stroke.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. The plant is cultivated all around the globe as a vegetable.
Celery can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.
On finding a natural ingredient with no side effect for the treatment of patients with acute ischemic stroke, researchers evaluated the Dl-3-n-butylphthalide (NBP), first isolated from the seeds of celery, efficacy in animal models of stroke.
The randomized, double-blind, double-dummy trial included 573 patients within 48 hours of onset of ischemic stroke in China.
Patients were randomly assigned to receive a 14-day infusion of NBP followed by an NBP capsule, a 14-day infusion of NBP followed by aspirin, or a 14-day infusion of ozagrel followed by aspirin.
After taking into account co and confounder, among the 535 subjects included in the efficacy analysis, 90-day treatment with NBP demonstrated a significant improvement than 14-day treatment with ozagrel as measured by the modified Rankin scale (mRS).
Where Ozagrel (INN) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.
According to Barthel index at day 90, there is no significant difference among the three groups. The rate of adverse events was similar among the three groups.
Furthermore, on a stroke induced by the middle cerebral artery occlusion (MCAO) in spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY), researchers compared the results of the pre-treatment of NBP administered to SHR and WKY daily for two months prior to MCAO and post-treatment of NBP given daily for seven consecutive days after MCAO.
In SHR, NBP pre- and post-treatment significantly lowered neurological deficit scores, reduced infarct volume, and minimized pathological changes in the penumbra area compared to oil-vehicle treated controls.
In other words, NBP pre- and post-treatment reduced the potential damage penumbra area through its neuroprotective activity.
However, in WKY, these beneficial effects were observed only in the post-treatment group, compared to SHR.
Dr. Zhang L, at the end of the experiment, wrote, "NBP could exert both preventive and therapeutic effects on ischemic stroke in SHR, but only exerted a therapeutic effect in WKY".
Taken altogether, Chinese celery processed high amounts of Dl-3-n-butylphthalide (NBP) may be considered a functional food for the post-treatment of patients with stroke.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Ninety-day administration of dl-3-n-butylphthalide for acute ischemic stroke: a randomized, double-blind trial and Cui LY1, Zhu YC, Gao S, Wang JM, Peng B, Ni J, Zhou LX, He J, Ma XQ.(PubMed)
(2) DL-3-n-Butylphthalide, an anti-oxidant agent, prevents neurological deficits and cerebral injury following stroke per functional analysis, magnetic resonance imaging and histological assessment by Zhang L1, Yu WH, Wang YX, Wang C, Zhao F, Qi W, Chan WM, Huang Y, Wai MS, Dong J, Yew DT.(PubMed)
(3) Stroke and Nutrition: A Review of Studies by Mehdi Foroughi,2 Mohsen Akhavanzanjani,2 Zahra Maghsoudi,2 Reza Ghiasvand,1,2Fariborz Khorvash,3 and Gholamreza Askari. (PMC)
Stroke is a medical condition caused by reduced blood flow to the brain, leading to the death of brain cells due to lack of oxygen or bleeding.
In other words, a stroke can either be results of a blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke).
A mini-stroke is a temporary disruption of blood flow to the brain that only causes some disruption to the brain with inducing permanent damage.
Depending on the parts of the neuron being damage, patients may experience different symptoms. However, most common symptoms of stroke include paralysis or numbness of the face, arm or leg, problems in vision, speaking, walking and persistent headache.
Certain medical conditions such as diabetes. heart diseases, long-term use of tobacco, the increase in age, ethnicity are some prevalent risk factors of stroke.
Out of many risk factors, people who have hypertension, particularly untreated hypertension and follow the Western diet are at increased risk of the onset of stroke, according to epidemiological studies.
In examining the post-stroke patients, a poor diet pattern with a high in saturated and trans fat, red meat and processed foods have been found in the high percentage, compared to the traditional diet.
Dr. Mehdi Foroughi, the lead scientist in the study of poor diet in risk of stoke wrote, " adherence to the improvements in nutrition and diet can reduce the incidence of stroke. Higher antioxidant, vitamins, potassium, calcium, vegetables, fruits, whole grain intake, and adherence to the Mediterranean diet or DASH diet can lower stroke incidence".
The statement clearly suggested that a healthy diet rich in fruits and vegetable and whole grain and low in red meat, saturated fat and trans fat, and processed food is the best for prevention and stroke.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. The plant is cultivated all around the globe as a vegetable.
Celery can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.
On finding a natural ingredient with no side effect for the treatment of patients with acute ischemic stroke, researchers evaluated the Dl-3-n-butylphthalide (NBP), first isolated from the seeds of celery, efficacy in animal models of stroke.
The randomized, double-blind, double-dummy trial included 573 patients within 48 hours of onset of ischemic stroke in China.
Patients were randomly assigned to receive a 14-day infusion of NBP followed by an NBP capsule, a 14-day infusion of NBP followed by aspirin, or a 14-day infusion of ozagrel followed by aspirin.
After taking into account co and confounder, among the 535 subjects included in the efficacy analysis, 90-day treatment with NBP demonstrated a significant improvement than 14-day treatment with ozagrel as measured by the modified Rankin scale (mRS).
Where Ozagrel (INN) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.
According to Barthel index at day 90, there is no significant difference among the three groups. The rate of adverse events was similar among the three groups.
Furthermore, on a stroke induced by the middle cerebral artery occlusion (MCAO) in spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY), researchers compared the results of the pre-treatment of NBP administered to SHR and WKY daily for two months prior to MCAO and post-treatment of NBP given daily for seven consecutive days after MCAO.
In SHR, NBP pre- and post-treatment significantly lowered neurological deficit scores, reduced infarct volume, and minimized pathological changes in the penumbra area compared to oil-vehicle treated controls.
In other words, NBP pre- and post-treatment reduced the potential damage penumbra area through its neuroprotective activity.
However, in WKY, these beneficial effects were observed only in the post-treatment group, compared to SHR.
Dr. Zhang L, at the end of the experiment, wrote, "NBP could exert both preventive and therapeutic effects on ischemic stroke in SHR, but only exerted a therapeutic effect in WKY".
Taken altogether, Chinese celery processed high amounts of Dl-3-n-butylphthalide (NBP) may be considered a functional food for the post-treatment of patients with stroke.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Ninety-day administration of dl-3-n-butylphthalide for acute ischemic stroke: a randomized, double-blind trial and Cui LY1, Zhu YC, Gao S, Wang JM, Peng B, Ni J, Zhou LX, He J, Ma XQ.(PubMed)
(2) DL-3-n-Butylphthalide, an anti-oxidant agent, prevents neurological deficits and cerebral injury following stroke per functional analysis, magnetic resonance imaging and histological assessment by Zhang L1, Yu WH, Wang YX, Wang C, Zhao F, Qi W, Chan WM, Huang Y, Wai MS, Dong J, Yew DT.(PubMed)
(3) Stroke and Nutrition: A Review of Studies by Mehdi Foroughi,2 Mohsen Akhavanzanjani,2 Zahra Maghsoudi,2 Reza Ghiasvand,1,2Fariborz Khorvash,3 and Gholamreza Askari. (PMC)
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