Scientists may have found a natural alternative for the treatment of allergies, according to studies.
Allergies are a faulty reaction of the immune systematic responses against harmful substances that enter the body.
Symptoms and diseases associated with allergy include sinus swelling, seasonal and returning allergies, hay fever and nasal allergies.
Believe or not, Penicillin, antibiotic medicine is the most common allergy trigger in drug allergies. 10 percent of people are allergic after using the medicine.
According to the statistics, in the US, approximately, more than 50 million Americans have experienced various types of allergies each year and 15 million Americans have food allergies, including 5.9 million children under age 18.
In other words, 1 in 13 children suffers from a food allergy. About 30 percent of children with food allergies are allergic to more than one food.
The findings strongly suggested that foods are the most common and major cause of the allergic onset.
Dr. Ruchi S. Gupta and colleagues in the allergic team in examining the food allergies in children wrote, "Overall, estimated current FA prevalence was 7.6%,.The most prevalent allergens were peanut (2.2%), milk (1.9%), shellfish (1.3%), and tree nut (1.2%)".
And, "Among food-allergic children, 42.3% reported ≥1 severe FA and 39.9% reported multiple FA. Furthermore, 19.0% reported ≥1 FA-related emergency department visit in the previous year and 42.0% reported ≥1-lifetime FA-related emergency department visit, whereas 40.7% had a current epinephrine autoinjector prescription.
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural compound for the treatment of allergies examined the honey effects in the treatment of allergic rhinitis (AR).
The prospective randomized placebo-controlled study included 40 AR patients divided equally into a case group and a control group. All the subjects received a daily dose of 10 mg of loratadine for 4 weeks.
The case group then ingested 1 g/kg body weight of honey daily in separate doses for the 4-week period. The control group ingested the same dose of honey-flavored corn syrup as a placebo.
According to the AR symptoms scored at the start, week 4, and week 8 of the study, at week 4, both groups showed progressive improvement in the symptoms, however, at week 8, only the case group showed continuous improvement in the symptom score.
The ingested honey group showed a significant improvement in individual AR symptoms after week 8 and the efficacy in reducing the symptoms persisted for a month after the cessation of the honey treatment.
The results suggested that honey processed certain chemical compounds that were not found in the corn syrup for the treatment of AR.
Some researchers suggested that long-term intake of raw honey can help to ameliorate allergy symptoms by regularly exposing to pollen, similarly to the allergy injection in desensitizing pollen-program.
If this result is true then only local honey can process the anti-AR symptoms compared to honey unlocalized pollen.
Taken altogether, honey may be considered a functional remedy for the prevention and treatment of AR symptoms, regardless of the types of honey, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Ingestion of honey improves the symptoms of allergic rhinitis: evidence from a randomized placebo-controlled trial in the East coast of Peninsular Malaysia by Asha'ari ZA1, Ahmad MZ, Jihan WS, Che CM, Leman I. (PubMed)
(2) Will honey relieve my seasonal allergies? by Allergists
(3) The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States by Ruchi S. Gupta, Christopher M. Warren, Bridget M. Smith, Jesse A. Blumenstock, Jialing Jiang, Matthew M. Davis, Kari C. Nadeau. (APP News and Journals)
Tuesday, March 19, 2019
Sinigrin May Be The Potential Anti Atherosclerosis Chemical Compound, According to Studies
Sinigrin may be used as a bioactive ingredient for the prevention and treatment of atherosclerosis, according to studies.
Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
According to the statistics provided by Atherosclerosis Open Acess, 32% of deaths account for atherosclerosis. 13.8% prevalence is among adults of 20 years and above. In 2010, coronary heart disease mortality rate was about 60%.
Risk factors of atherosclerosis include high blood pressure and cholesterol, diabetes, being overweight or obese, unhealthy diet, family history of heart disease and physical inactivity, particularly smoking.
Some researchers suggested that since cholesterol make up a big part in the plaque, an unhealthy diet with a high saturated trans fat, red meat and processed meat may be the major cause of atherosclerosis.
In other words, the Western diet is one of the major culprits that cause the majority of cases of atherosclerosis.
Dr. Meifang Wang, the lead researcher in the study of "Western Diet Increases Inflammatory Responses and Atherosclerosis Progression via IGF-1 Receptor in ApoE-Deficient Mice" said, "....lowered circulating IGF-1 increases atherosclerosis progression in atherosclerosis-prone apolipoprotein E-deficient mice (ApoE−/−) while increased circulating IGF-1 downregulates vascular pro-inflammatory cytokine gene expression, reduces systemic and vascular oxidant stress, vascular cytokine expression, and decreases atherosclerosis progression".
And, "the pro-inflammatory phenotype that is enhanced by WD in ApoE−/− mice is further enhanced by specific IGF1R deficiency in monocytes/macrophages, and may consequently increase atherosclerosis progression".
The results suggested that the Western diet-induced atherosclerosis progression through the increase of production of pro-inflammatory cytokines and decrease of the function of insulin-like growth factor-1 (IGF-1) as a mediator of anabolic responses in many cells and tissues.
Sinigrin is a phytochemical glucosinolate, belonging to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Scientists on finding a natural bioactive compound for the treatment of atherosclerosis examined the effect of sinigrin against plaque accumulation on the arterial walls.
On atherosclerosis in ApoE-/- mice, injection sinigrin exerted a significant effect in the inhibition of the serum concentrations of lactate dehydrogenase (LDH), triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), calcium (Ca2+), and pro-inflammatory cytokines associated with plaque accumulated on the wall of the arteries.
Furthermore, oral administration of sinigrin attenuated the mRNA expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), which form a part of immunoglobulin superfamily in inflammatory and immune responses.
Moreover, injection also reduced the expression of genes C-C motif chemokine ligand 2 (CCL2), and CCL5 on aorta tissues associated with the risk of atherosclerosis.
The expression of low-density lipoprotein was also reduced by the injection of sinigrin observed by some keys regulators of cholesterol such as sterol regulatory element-binding protein-2 (SREBP-2).
Interestingly, increased the concentration of sinigrin at the dose up to 100 μg/ml also significantly suppressed the levels of Tumor necrosis factor (TNF-α) and nuclear translocation of NF-κB, cell signaling protein (cytokine) involved in systemic inflammation.
Additionally, at a contraction ut to 100 μg/ml, sinigrin inhibited the c-Jun-NH (2)-terminal kinase (JNK) signaling pathway which plays a critical role in regulating cellular differentiation.
The findings strongly suggested that sinigrin inhibited the onset of atherosclerosis through lowering the low-density lipoproteins and mechanisms associated with inflammatory induction of plaque accumulation on the arterial wall.
Dr. Jang YJ, the lead scientist wrote, "sinigrin decreases the TNF-α-stimulated VCAM-1 expression through the suppression of NF-κB and MAP kinases signaling pathways, Overall, sinigrin has the potential to be used in reducing the risks of atherosclerosis".
Taken altogether, sinigrin may be considered a supplement for the prevention and combined with the primary therapy for the treatment of atherosclerosis, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression by Jang YJ1, Park B1, Lee HW1, Park HJ1, Koo HJ2, Kim BO3, Sohn EH4, Um SH5, Pyo S. (PubMed)
(2) Western Diet Increases Inflammatory Responses and Atherosclerosis Progression via IGF-1 Receptor in ApoE-Deficient Mice by Meifang Wang, Yusuke Higashi, Derek Wang, Ronald Korthuis, and Patrice Delafontaine. (FASEB Journal)
Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
According to the statistics provided by Atherosclerosis Open Acess, 32% of deaths account for atherosclerosis. 13.8% prevalence is among adults of 20 years and above. In 2010, coronary heart disease mortality rate was about 60%.
Risk factors of atherosclerosis include high blood pressure and cholesterol, diabetes, being overweight or obese, unhealthy diet, family history of heart disease and physical inactivity, particularly smoking.
Some researchers suggested that since cholesterol make up a big part in the plaque, an unhealthy diet with a high saturated trans fat, red meat and processed meat may be the major cause of atherosclerosis.
In other words, the Western diet is one of the major culprits that cause the majority of cases of atherosclerosis.
Dr. Meifang Wang, the lead researcher in the study of "Western Diet Increases Inflammatory Responses and Atherosclerosis Progression via IGF-1 Receptor in ApoE-Deficient Mice" said, "....lowered circulating IGF-1 increases atherosclerosis progression in atherosclerosis-prone apolipoprotein E-deficient mice (ApoE−/−) while increased circulating IGF-1 downregulates vascular pro-inflammatory cytokine gene expression, reduces systemic and vascular oxidant stress, vascular cytokine expression, and decreases atherosclerosis progression".
And, "the pro-inflammatory phenotype that is enhanced by WD in ApoE−/− mice is further enhanced by specific IGF1R deficiency in monocytes/macrophages, and may consequently increase atherosclerosis progression".
The results suggested that the Western diet-induced atherosclerosis progression through the increase of production of pro-inflammatory cytokines and decrease of the function of insulin-like growth factor-1 (IGF-1) as a mediator of anabolic responses in many cells and tissues.
Sinigrin is a phytochemical glucosinolate, belonging to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Scientists on finding a natural bioactive compound for the treatment of atherosclerosis examined the effect of sinigrin against plaque accumulation on the arterial walls.
On atherosclerosis in ApoE-/- mice, injection sinigrin exerted a significant effect in the inhibition of the serum concentrations of lactate dehydrogenase (LDH), triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), calcium (Ca2+), and pro-inflammatory cytokines associated with plaque accumulated on the wall of the arteries.
Furthermore, oral administration of sinigrin attenuated the mRNA expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), which form a part of immunoglobulin superfamily in inflammatory and immune responses.
Moreover, injection also reduced the expression of genes C-C motif chemokine ligand 2 (CCL2), and CCL5 on aorta tissues associated with the risk of atherosclerosis.
The expression of low-density lipoprotein was also reduced by the injection of sinigrin observed by some keys regulators of cholesterol such as sterol regulatory element-binding protein-2 (SREBP-2).
Interestingly, increased the concentration of sinigrin at the dose up to 100 μg/ml also significantly suppressed the levels of Tumor necrosis factor (TNF-α) and nuclear translocation of NF-κB, cell signaling protein (cytokine) involved in systemic inflammation.
Additionally, at a contraction ut to 100 μg/ml, sinigrin inhibited the c-Jun-NH (2)-terminal kinase (JNK) signaling pathway which plays a critical role in regulating cellular differentiation.
The findings strongly suggested that sinigrin inhibited the onset of atherosclerosis through lowering the low-density lipoproteins and mechanisms associated with inflammatory induction of plaque accumulation on the arterial wall.
Dr. Jang YJ, the lead scientist wrote, "sinigrin decreases the TNF-α-stimulated VCAM-1 expression through the suppression of NF-κB and MAP kinases signaling pathways, Overall, sinigrin has the potential to be used in reducing the risks of atherosclerosis".
Taken altogether, sinigrin may be considered a supplement for the prevention and combined with the primary therapy for the treatment of atherosclerosis, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression by Jang YJ1, Park B1, Lee HW1, Park HJ1, Koo HJ2, Kim BO3, Sohn EH4, Um SH5, Pyo S. (PubMed)
(2) Western Diet Increases Inflammatory Responses and Atherosclerosis Progression via IGF-1 Receptor in ApoE-Deficient Mice by Meifang Wang, Yusuke Higashi, Derek Wang, Ronald Korthuis, and Patrice Delafontaine. (FASEB Journal)
Monday, March 18, 2019
Herbal Calendula, the Potent Anti Edema Functional Remedy
Herbal Calendula may have a potential effect in reducing risk and treatment of edema, some scientists suggested.
Edema is a condition characterized by an abnormal accumulation of fluid in certain tissues within the body due to injury or inflammation.
In most cases, edema occurs under the surfaces of the skin in the leg and ankle. However, fluids can also be accumulated in the lungs (pulmonary edema).
Without the assistance of diagnosis, researchers can not pinpoint the exact causes of edema.
There are numbers of risk factor associated with the onset of the swellings, such as low levels of albumin that keeps the blood in the vessels, allergic reaction, blood clots. Some medical conditions such as congestive heart failure, kidney diseases and long-term intake medicine such as NSAIDs and calcium channel blockers also increased the risk of edema.
Some researchers suggested that under normal conditions, medicine that removes excess fluid and reduces intake salt can be effective. However, if the condition of edema is caused by underlying disease, separated medicine treatment may be required.
If you are experiencing symptoms of heavy leg and ankle and shortness of breath, please check with your doctor to rule out the edema possibility.
Calendula is also known as pot marigold, annual or perennial herbaceous plants of about 12–20 species of genus Calendula, belonging to the family Asteraceae, native to Southern Europe.
The herb has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and to treat abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.
Chemical ingredients
Besides major chemical constituents of triterpenoids, flavonoids, coumarines, quinones, volatile oil,carotenoids and amino acids, the herb also contains loliolide (calendin), calendulin and n-paraffins.
In the study to examine the anti-inflammatory effect of Calendula officinalis flower extract against paw edema, researchers at the Amala Cancer Research Centre, launched an investigation in the paw edema of animals induced by carrageenan and dextran.
Oral injection of 250 and 500 mg/kg body weight of Calendula extract exerted a significant inhibition (50.6 and 65.9% respectively) in paw edema of animals by 41.9% in the carrageenan group and 42.4% in the dextran group, respectively through the anti-inflammatory activity.
In chronic inflammatory model induced by injection of formalin, administration of 250 and 500 mg/kg body weight of Calendula extract produced an inhibition of 32.9 and 62.3% respectively compared to controls.
Further examination also found that proinflammatory cytokines activated by macrophage of the immune system in the response to infection are also reduced significantly.
Other proinflammatory proteins such as IL- 1beta, IL-6, TNF-alpha and IFN-gamma and acute phase protein, C- reactive protein (CRP) in edema mice produced by LPS injection were inhibited significantly by the extracts in different doses.
These results suggested that herbal Calendula inhibits edema caused by inflammation through its anti-inflammatory expression.
Additionally, in the study to reaffirm the efficacy of Calendula anti-inflammation against the progression of edema, researchers at the niversità di Trento conducted a differentiation on the anti-inflammatory chemical constituents of the herb.
13 out of 15 terpenoids from Calendula were found to process topical anti-inflammatory activities with respect to the inhibition of croton oil-induced ear edema in the mouse.
Three derivatives of Rings A, D, and E of faradiol, the C(16) benzyl ether 15, the C(30) aldehyde 24, and the C(30) primary alcohol 25 isolated from the herb also showed a significantly improved anti-inflammatory potency.
Taken altogether, herbal Calendula with the abundant anti-inflammatory bioactive compounds may have a potential effect in the prevention and treatment of inflammatory edema.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Phytochemical Constituents and PharmacologicalActivities of Calendula officinalis Linn (Asteraceae): A Review by BP Muley, SS Khadabadi and NB Banarase (Tropical Journal of Pharmaceutical Research)
(2)Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action by Preethi KC, Kuttan G, Kuttan R.(PubMed)
(3) Improved anti-inflammatory activity of three new terpenoids derived, by systematic chemical modifications, from the abundant triterpenes of the flowery plant Calendula officinalis by Neukirch H, D'Ambrosio M, Sosa S, Altinier G, Della Loggia R, Guerriero A.(PubMed)
Edema is a condition characterized by an abnormal accumulation of fluid in certain tissues within the body due to injury or inflammation.
In most cases, edema occurs under the surfaces of the skin in the leg and ankle. However, fluids can also be accumulated in the lungs (pulmonary edema).
Without the assistance of diagnosis, researchers can not pinpoint the exact causes of edema.
There are numbers of risk factor associated with the onset of the swellings, such as low levels of albumin that keeps the blood in the vessels, allergic reaction, blood clots. Some medical conditions such as congestive heart failure, kidney diseases and long-term intake medicine such as NSAIDs and calcium channel blockers also increased the risk of edema.
Some researchers suggested that under normal conditions, medicine that removes excess fluid and reduces intake salt can be effective. However, if the condition of edema is caused by underlying disease, separated medicine treatment may be required.
If you are experiencing symptoms of heavy leg and ankle and shortness of breath, please check with your doctor to rule out the edema possibility.
Calendula is also known as pot marigold, annual or perennial herbaceous plants of about 12–20 species of genus Calendula, belonging to the family Asteraceae, native to Southern Europe.
The herb has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and to treat abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.
Chemical ingredients
Besides major chemical constituents of triterpenoids, flavonoids, coumarines, quinones, volatile oil,carotenoids and amino acids, the herb also contains loliolide (calendin), calendulin and n-paraffins.
In the study to examine the anti-inflammatory effect of Calendula officinalis flower extract against paw edema, researchers at the Amala Cancer Research Centre, launched an investigation in the paw edema of animals induced by carrageenan and dextran.
Oral injection of 250 and 500 mg/kg body weight of Calendula extract exerted a significant inhibition (50.6 and 65.9% respectively) in paw edema of animals by 41.9% in the carrageenan group and 42.4% in the dextran group, respectively through the anti-inflammatory activity.
In chronic inflammatory model induced by injection of formalin, administration of 250 and 500 mg/kg body weight of Calendula extract produced an inhibition of 32.9 and 62.3% respectively compared to controls.
Further examination also found that proinflammatory cytokines activated by macrophage of the immune system in the response to infection are also reduced significantly.
Other proinflammatory proteins such as IL- 1beta, IL-6, TNF-alpha and IFN-gamma and acute phase protein, C- reactive protein (CRP) in edema mice produced by LPS injection were inhibited significantly by the extracts in different doses.
These results suggested that herbal Calendula inhibits edema caused by inflammation through its anti-inflammatory expression.
Additionally, in the study to reaffirm the efficacy of Calendula anti-inflammation against the progression of edema, researchers at the niversità di Trento conducted a differentiation on the anti-inflammatory chemical constituents of the herb.
13 out of 15 terpenoids from Calendula were found to process topical anti-inflammatory activities with respect to the inhibition of croton oil-induced ear edema in the mouse.
Three derivatives of Rings A, D, and E of faradiol, the C(16) benzyl ether 15, the C(30) aldehyde 24, and the C(30) primary alcohol 25 isolated from the herb also showed a significantly improved anti-inflammatory potency.
Taken altogether, herbal Calendula with the abundant anti-inflammatory bioactive compounds may have a potential effect in the prevention and treatment of inflammatory edema.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Phytochemical Constituents and PharmacologicalActivities of Calendula officinalis Linn (Asteraceae): A Review by BP Muley, SS Khadabadi and NB Banarase (Tropical Journal of Pharmaceutical Research)
(2)Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action by Preethi KC, Kuttan G, Kuttan R.(PubMed)
(3) Improved anti-inflammatory activity of three new terpenoids derived, by systematic chemical modifications, from the abundant triterpenes of the flowery plant Calendula officinalis by Neukirch H, D'Ambrosio M, Sosa S, Altinier G, Della Loggia R, Guerriero A.(PubMed)
Arctostaphylos uva-ursi, the Herbal Remedy Which Kills Bladder Cancer Cells in Vitro
Herbal Arctostaphylos uva-ursi may have a potential in the prevention and treatment of bladder cancer, some scientists suggested.
Bladder cancer is a medical and chronic condition characterized by cell growth uncontrollably and disorderly in the tissue of the bladder.
Most bladder cancer starts first on the surface of the inner lining tissue of the bladder. As the cancer progress to the advanced stage, the malignant cells can infect other healthy tissue through the circulation of blood and fluid.
Bladder cancer that spreads to other parts of the body is known as metastatic bladder cancer.
According to the statistic, every year, approximately, over 80,000 adults, including 62,380 men and 18,810 women in the United States are diagnosed with bladder cancer, causing the of deaths of 12,520 men and 4,720 women.
The 5-year relative survival rate of all stages of bladder cancer is about 77%. However, the 5-year relative survival rate for people diagnosed with stage 0 of bladder cancer is about 98%,
The statistic strongly suggested, if bladder cancer is diagnosed in the early stage, it is treatable.
The exact causes of bladder cancer are unknown. However, the age of 50 and over, men, smoking, long-term exposure to harmful chemicals are associated with the increased risk of the disease,
Some researchers suggested certain medical conditions such as diabetes, previous treatment of radiotherapy and chemotherapy and early menopause are also some of the prevalent risk factors that may increase the early onset of bladder cancer.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stone, pelvic pain, etc.
The Ingredients
It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
In the reaffirm of traditional medicine use of herbal Arctostaphylos uva-ursi for treatment of various types of cancer, researchers at the Chung-Ang University College of Medicine launched an investigation to examine the effects of Arbutin, glycosylated hydroquinone extracted from the bearberry plant (Arctostaphylos species) on TCCSUP human bladder carcinoma cell.
At the dose at concentrations of < 500 microg/ml, Arbutin did not exhibit any cytotoxic effects in TCCSUP cells.
In different concentrations that are higher than 500microg/ml, Arbutin significantly decreased TCCSUP cell proliferation in a time-dependent manner.
According to the cell cycle analysis, arbutin strongly disrupted the cell cycle also in a time-dependent manner.
Furthermore, arbutin led to the inactivation of the extracellular signal-regulated kinase (ERK), which is known to critically regulate cell proliferation.
The in-depth analysis also found that arbutin markedly increases the expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1)which is considered a key mediator of p53-dependent cell cycle arrest.
Where p53, also known as TP53, is a protein which processes a function in regulating the cell cycle division and hence functions as a tumor suppression.
Dr. Li H, the lead author, after taking into account of co and confounders, said, " arbutin inhibits TCCSUP cell proliferation via ERK inactivation and p21 up-regulation".
Abnormal activation of ERK was found to in human cancer due to DNA mutation. The combination of ERK pathway inhibitors (cytostatic agents) and conventional anticancer drugs (cytotoxic agents) are an excellent basis for scientists to develop new chemotherapeutic strategies against cancer.
Taken altogether, herbal Arctostaphylos uva-ursi containing a high volume of Arbutin may be considered a functional herb for the prevention and combined with conventional medicine for treatment of bladder cancer,
However, further data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of herbal Arctostaphylos uva-ursi anti-bladder cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Arbutin inhibits TCCSUP human bladder cancer cell proliferation via up-regulation of p21 By Li H, Jeong YM, Kim SY, Kim MK, Kim DS.(PubMed)
Bladder cancer is a medical and chronic condition characterized by cell growth uncontrollably and disorderly in the tissue of the bladder.
Most bladder cancer starts first on the surface of the inner lining tissue of the bladder. As the cancer progress to the advanced stage, the malignant cells can infect other healthy tissue through the circulation of blood and fluid.
Bladder cancer that spreads to other parts of the body is known as metastatic bladder cancer.
According to the statistic, every year, approximately, over 80,000 adults, including 62,380 men and 18,810 women in the United States are diagnosed with bladder cancer, causing the of deaths of 12,520 men and 4,720 women.
The 5-year relative survival rate of all stages of bladder cancer is about 77%. However, the 5-year relative survival rate for people diagnosed with stage 0 of bladder cancer is about 98%,
The statistic strongly suggested, if bladder cancer is diagnosed in the early stage, it is treatable.
The exact causes of bladder cancer are unknown. However, the age of 50 and over, men, smoking, long-term exposure to harmful chemicals are associated with the increased risk of the disease,
Some researchers suggested certain medical conditions such as diabetes, previous treatment of radiotherapy and chemotherapy and early menopause are also some of the prevalent risk factors that may increase the early onset of bladder cancer.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stone, pelvic pain, etc.
The Ingredients
It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
In the reaffirm of traditional medicine use of herbal Arctostaphylos uva-ursi for treatment of various types of cancer, researchers at the Chung-Ang University College of Medicine launched an investigation to examine the effects of Arbutin, glycosylated hydroquinone extracted from the bearberry plant (Arctostaphylos species) on TCCSUP human bladder carcinoma cell.
At the dose at concentrations of < 500 microg/ml, Arbutin did not exhibit any cytotoxic effects in TCCSUP cells.
In different concentrations that are higher than 500microg/ml, Arbutin significantly decreased TCCSUP cell proliferation in a time-dependent manner.
According to the cell cycle analysis, arbutin strongly disrupted the cell cycle also in a time-dependent manner.
Furthermore, arbutin led to the inactivation of the extracellular signal-regulated kinase (ERK), which is known to critically regulate cell proliferation.
The in-depth analysis also found that arbutin markedly increases the expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1)which is considered a key mediator of p53-dependent cell cycle arrest.
Where p53, also known as TP53, is a protein which processes a function in regulating the cell cycle division and hence functions as a tumor suppression.
Dr. Li H, the lead author, after taking into account of co and confounders, said, " arbutin inhibits TCCSUP cell proliferation via ERK inactivation and p21 up-regulation".
Abnormal activation of ERK was found to in human cancer due to DNA mutation. The combination of ERK pathway inhibitors (cytostatic agents) and conventional anticancer drugs (cytotoxic agents) are an excellent basis for scientists to develop new chemotherapeutic strategies against cancer.
Taken altogether, herbal Arctostaphylos uva-ursi containing a high volume of Arbutin may be considered a functional herb for the prevention and combined with conventional medicine for treatment of bladder cancer,
However, further data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of herbal Arctostaphylos uva-ursi anti-bladder cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Arbutin inhibits TCCSUP human bladder cancer cell proliferation via up-regulation of p21 By Li H, Jeong YM, Kim SY, Kim MK, Kim DS.(PubMed)
Sunday, March 17, 2019
Aloe Vera Inhibited Symptoms and Progression of Polycystic Ovarian Syndrome With No Side Effects, According to Studies
Scientists may have found a natural whole herb for the treatment of polycystic ovarian syndrome (PCOs) with no side effects some studies suggested.
The polycystic ovarian syndrome is an endocrinologic disease caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries
PCOs induced enlarged ovaries can facilitate the onset of certain complications, including hormone imbalance( excessive androgen), male pattern hair development, acne, irregular period or absence of period, weight gain and infertility.
According to the statistic, polycystic ovary syndrome (PCOs) is a health condition, affecting 1 in 10 women of childbearing age. in the Western world.
The exact causes of polycystic ovary syndrome (PCOs) are unknown, However, according to epidemiological studies, high levels of androgens. and insulin is the 2 characteristics of women with the syndrome.
Women who have the onset of polycystic ovary syndrome (PCOs) also experience additional health problems, including diabetes, high blood pressure, and cholesterol, sleep problem and psychological symptoms of depression and anxiety.
According to the study by Desai BN, Maharjan RH, Nampoothiri LP. almost 70% of PCOS women have abnormal serum lipid levels (dyslipidemia) and 50% of these women are obese.
Several classes of pharmacological agents have been used to manage dyslipidemia. However, studies have shown adverse effects associated with these drugs.
Compared to other risk factors, genetic preposition has been under intensified studies by many scientists. Dr. N Prapas, the lead author in the study "Genetics of Polycystic Ovary Syndrome" said, "Polycystic ovary syndrome has been proven to be a familial condition....the role of genetic factors in PCOS is strongly supported" and
" Some genes (such as Gly972Arg, CAPN10) have shown altered expression suggesting that the genetic abnormality in PCOS affects signal transduction pathways controlling steroidogenesis, steroid hormones action, gonadotrophin action and regulation, insulin action and secretion, energy homeostasis, chronic inflammation, and others".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
The plant has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc.
The herb also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding a natural ingredient or whole food for the treatment of polycystic ovarian syndrome (PCOs) with no side effects, researchers examine the effects of Aloe vera in Charles Foster female rats induced-PCOs PCOS by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days).
All rats before injection of the Aloe vera expressed a significant increase of hyperglycemia and 90% rats also showed elevated plasma triglycerides, elevated LDL cholesterol levels, and lowered plasma HDL cholesterol levels, an indication of a dyslipidemic profile.
PCOS positive rats with an aberrant lipid profile were selected to the treatment with AVG formulation (1 ml (10 mg)/day, 30 days) administered orally.
Infection of AVG in PCOS rats exhibited a significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol.
The gel treatment also completely restore the abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities.
These results firmly suggested AVG which contains a high amount of phyto components processes an anti-hyperlipidemic effect not only on PCOS but also the associated metabolic complication: dyslipidemia.
Continuously, in the study included five-month-old Charles Foster female rats were orally fed with letrozole, a non-steroidal aromatase inhibitor, to induce PCOS, researchers once again confirmed that
* Aloe vera gel formulation (1 ml dose daily for 45 days) restores their estrus cyclicity, glucose sensitivity, and steroidogenic activity.
* Co-treatment of the inductive agent (letrozole) with the Aloe vera gel prevented the development of the PCO phenotype caused by the injection of the inductive agent (letrozole).
Dr.Maharjan R, the lead author at the final day of the experiment said, " Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity".
Taken altogether, Aloe Vera may be considered a functional food for the prevention and treatment of
polycystic ovarian syndrome (PCOs) without inducing any side effects,
However, oral administration in high amounts of Aloe vera should only be prescribed by the experts in the related field
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model (PubMed)
(4) Genetics of Polycystic Ovary Syndrome by N Prapas, A Karkanaki, I Prapas, I Kalogiannidis, I Katsikis, and D Panidis. (PMC)
The polycystic ovarian syndrome is an endocrinologic disease caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries
PCOs induced enlarged ovaries can facilitate the onset of certain complications, including hormone imbalance( excessive androgen), male pattern hair development, acne, irregular period or absence of period, weight gain and infertility.
According to the statistic, polycystic ovary syndrome (PCOs) is a health condition, affecting 1 in 10 women of childbearing age. in the Western world.
The exact causes of polycystic ovary syndrome (PCOs) are unknown, However, according to epidemiological studies, high levels of androgens. and insulin is the 2 characteristics of women with the syndrome.
Women who have the onset of polycystic ovary syndrome (PCOs) also experience additional health problems, including diabetes, high blood pressure, and cholesterol, sleep problem and psychological symptoms of depression and anxiety.
According to the study by Desai BN, Maharjan RH, Nampoothiri LP. almost 70% of PCOS women have abnormal serum lipid levels (dyslipidemia) and 50% of these women are obese.
Several classes of pharmacological agents have been used to manage dyslipidemia. However, studies have shown adverse effects associated with these drugs.
Compared to other risk factors, genetic preposition has been under intensified studies by many scientists. Dr. N Prapas, the lead author in the study "Genetics of Polycystic Ovary Syndrome" said, "Polycystic ovary syndrome has been proven to be a familial condition....the role of genetic factors in PCOS is strongly supported" and
" Some genes (such as Gly972Arg, CAPN10) have shown altered expression suggesting that the genetic abnormality in PCOS affects signal transduction pathways controlling steroidogenesis, steroid hormones action, gonadotrophin action and regulation, insulin action and secretion, energy homeostasis, chronic inflammation, and others".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
The plant has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc.
The herb also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding a natural ingredient or whole food for the treatment of polycystic ovarian syndrome (PCOs) with no side effects, researchers examine the effects of Aloe vera in Charles Foster female rats induced-PCOs PCOS by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days).
All rats before injection of the Aloe vera expressed a significant increase of hyperglycemia and 90% rats also showed elevated plasma triglycerides, elevated LDL cholesterol levels, and lowered plasma HDL cholesterol levels, an indication of a dyslipidemic profile.
PCOS positive rats with an aberrant lipid profile were selected to the treatment with AVG formulation (1 ml (10 mg)/day, 30 days) administered orally.
Infection of AVG in PCOS rats exhibited a significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol.
The gel treatment also completely restore the abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities.
These results firmly suggested AVG which contains a high amount of phyto components processes an anti-hyperlipidemic effect not only on PCOS but also the associated metabolic complication: dyslipidemia.
Continuously, in the study included five-month-old Charles Foster female rats were orally fed with letrozole, a non-steroidal aromatase inhibitor, to induce PCOS, researchers once again confirmed that
* Aloe vera gel formulation (1 ml dose daily for 45 days) restores their estrus cyclicity, glucose sensitivity, and steroidogenic activity.
* Co-treatment of the inductive agent (letrozole) with the Aloe vera gel prevented the development of the PCO phenotype caused by the injection of the inductive agent (letrozole).
Dr.Maharjan R, the lead author at the final day of the experiment said, " Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity".
Taken altogether, Aloe Vera may be considered a functional food for the prevention and treatment of
polycystic ovarian syndrome (PCOs) without inducing any side effects,
However, oral administration in high amounts of Aloe vera should only be prescribed by the experts in the related field
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model (PubMed)
(4) Genetics of Polycystic Ovary Syndrome by N Prapas, A Karkanaki, I Prapas, I Kalogiannidis, I Katsikis, and D Panidis. (PMC)
Herbal Chamomile, The Best Functional Herb for the Prevention and Treatment of Insomnia
Scientists may have found a herbal medicine to treat insomnia with no side effects, according to the result of some studies.
Insomnia is a sign and symptom of sleep disorder in which a person has difficulty falling asleep and/or staying asleep or sleep of poor quality.
According to the statistic provided by the Sleep Education, insomnia affects millions of people in the US, 30 to 35% have brief symptoms of insomnia, 15 to 20% have a short-term insomnia disorder, which lasts less than three months and 10% have a chronic insomnia disorder, which occurs at least three times per week for at least three months.
And, one in three people suffers from some form of insomnia during their lifetime and women suffer from insomnia more often than men.
There is no single cause of insomnia. Researchers suggested that psychiatric and medical conditions, such as stress and anxiety and chronic illness such as diabetes, cardiovascular disease, musculoskeletal disorders, kidney disease, unhealthy sleep habits and long-term use of substances, are associated to some prevalent risk factors of the onset of insomnia.
In other words, anything that causes the disruption of the brain sleep-awake cycle or the brain function to turn on and off the sleep-wake cycle is the risk factor to the syndrome onset.
Long-term use of certain medication can also induce insomnia. The National Jewish Health suggested
antidepressants such as Prozac® and Zoloft, Dopamine agonists and anticonvulsants are some medications which can cause insomnia.
If you are taking one of these medicines and have a sleep problem, please make sure you discuss the problem with your doctors.
Long-term and untreated insomnia may increase the risk of the complication of anxiety, depression and heart failure and daytime trouble concentrating, and mood disturbances
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae.
The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Chamomile is one of the most popular herbs used for sleep disorders in herbal medicine. According to the Dr. Srivastava JK and research team at the Case Western Reserve University, many different preparations of the herb have been developed, the most popular of which is in the form of herbal tea consumed more than one million cups per day.
In the reaffirming the effect of chamomile used in traditional medicine for the treatment of insomnia, researchers at the University of Michigan launched an investigation to examine the preliminary efficacy and safety of chamomile for improving subjective sleep and daytime symptoms in patients with chronic insomnia.
The randomized, double-blind, placebo-controlled pilot trial included 34 patients aged 18-65 years with DSM-IV primary insomnia for ≥ 6-months.
Patients were randomized to 270 mg of chamomile twice daily or placebo for 28-days.
There were no significant differences between groups in changes in sleep diary measures, including total sleep time (TST), sleep efficiency, sleep latency, wake after sleep onset (WASO), sleep quality, and a number of awakenings.
Participants received the 270 mg chamomile show modest advantage on daytime functioning compared to placebo.
Intake of chamomile also exerted a moderate effect in sleep latency, nighttime awakenings, and Fatigue Severity Scale (FSS).
There were no differences in adverse events reported by the chamomile group compared to placebo.
Dr. Zick SM after taking the final assessment said, "Chamomile could provide modest benefits of daytime functioning and mixed benefits on sleep diary measures relative to placebo in adults with chronic primary insomnia".
DR. Wheatley D, in the classification of the medicinal plants for insomnia, once again suggested that chamomile improves the sleep quality of patients with insomnia may be attributed to the herbal medicine anxiolytic or sedative properties.
Taken altogether, chamomile may be considered a functional herb for the prevention and treatment of insomnia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Chamomile: A herbal medicine of the past with bright future by Srivastava JK1, Shankar E, Gupta S.(PubMed)
(2) Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study by Zick SM1, Wright BD, Sen A, Arnedt JT.(PubMed)
(3) Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. by Wheatley D.(PubMed)
Insomnia is a sign and symptom of sleep disorder in which a person has difficulty falling asleep and/or staying asleep or sleep of poor quality.
According to the statistic provided by the Sleep Education, insomnia affects millions of people in the US, 30 to 35% have brief symptoms of insomnia, 15 to 20% have a short-term insomnia disorder, which lasts less than three months and 10% have a chronic insomnia disorder, which occurs at least three times per week for at least three months.
And, one in three people suffers from some form of insomnia during their lifetime and women suffer from insomnia more often than men.
There is no single cause of insomnia. Researchers suggested that psychiatric and medical conditions, such as stress and anxiety and chronic illness such as diabetes, cardiovascular disease, musculoskeletal disorders, kidney disease, unhealthy sleep habits and long-term use of substances, are associated to some prevalent risk factors of the onset of insomnia.
In other words, anything that causes the disruption of the brain sleep-awake cycle or the brain function to turn on and off the sleep-wake cycle is the risk factor to the syndrome onset.
Long-term use of certain medication can also induce insomnia. The National Jewish Health suggested
antidepressants such as Prozac® and Zoloft, Dopamine agonists and anticonvulsants are some medications which can cause insomnia.
If you are taking one of these medicines and have a sleep problem, please make sure you discuss the problem with your doctors.
Long-term and untreated insomnia may increase the risk of the complication of anxiety, depression and heart failure and daytime trouble concentrating, and mood disturbances
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae.
The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Chamomile is one of the most popular herbs used for sleep disorders in herbal medicine. According to the Dr. Srivastava JK and research team at the Case Western Reserve University, many different preparations of the herb have been developed, the most popular of which is in the form of herbal tea consumed more than one million cups per day.
In the reaffirming the effect of chamomile used in traditional medicine for the treatment of insomnia, researchers at the University of Michigan launched an investigation to examine the preliminary efficacy and safety of chamomile for improving subjective sleep and daytime symptoms in patients with chronic insomnia.
The randomized, double-blind, placebo-controlled pilot trial included 34 patients aged 18-65 years with DSM-IV primary insomnia for ≥ 6-months.
Patients were randomized to 270 mg of chamomile twice daily or placebo for 28-days.
There were no significant differences between groups in changes in sleep diary measures, including total sleep time (TST), sleep efficiency, sleep latency, wake after sleep onset (WASO), sleep quality, and a number of awakenings.
Participants received the 270 mg chamomile show modest advantage on daytime functioning compared to placebo.
Intake of chamomile also exerted a moderate effect in sleep latency, nighttime awakenings, and Fatigue Severity Scale (FSS).
There were no differences in adverse events reported by the chamomile group compared to placebo.
Dr. Zick SM after taking the final assessment said, "Chamomile could provide modest benefits of daytime functioning and mixed benefits on sleep diary measures relative to placebo in adults with chronic primary insomnia".
DR. Wheatley D, in the classification of the medicinal plants for insomnia, once again suggested that chamomile improves the sleep quality of patients with insomnia may be attributed to the herbal medicine anxiolytic or sedative properties.
Taken altogether, chamomile may be considered a functional herb for the prevention and treatment of insomnia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Chamomile: A herbal medicine of the past with bright future by Srivastava JK1, Shankar E, Gupta S.(PubMed)
(2) Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study by Zick SM1, Wright BD, Sen A, Arnedt JT.(PubMed)
(3) Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. by Wheatley D.(PubMed)
Saturday, March 16, 2019
Banana, the Natural Antibiotic and Anti Oxidative Stress Functional Food
Banana may have a potential and substantial effect on balancing the levels of free radicals and antioxidants in the body, according to the studies.
Oxidative stress is a condition of imbalance of the ration of free radicals and antioxidant enzymes produced by the body, leading to the damage of cell, protein, and alternation of cell DNA.
The causes of oxidative are either associated with overexpression of free radicals and depressed the host antioxidant enzymes.
Free radicals are highly reactive molecules with the unpaired electron on the outer ring of the atom. In order for them to become balanced, they must donate or steal an electron from the stable molecules, leading to the chain of reaction which can not be stopped until the electrons on the outer ring are paired or inhibited by antioxidants.
This chain of domino's effect is known as oxidation.
Antioxidants are the stable molecules which inhibit oxidation.
There are 2 types of antioxidant in the human body. The antioxidants are produced by the host and antioxidant come from dietary sources.
Every day, our body is bombarded by the invasion of free radical. Believe or not, substances include fried foods, alcohol, tobacco smoke, pesticides, air pollutants, can produce harmful free radicals to our body.
Epidemiological studies agreed that oxidative stress is involved in several age-related conditions, including cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, neurodegenerative diseases, and cancer.
Dr. Seungyoun Jung,, the lead scientists in the evaluation of a healthy diet pattern and the risk of oxidative stress suggested, "Foods rich in healthy diets—characterized by a high intake of fruit, vegetables, and whole grains as well as a low intake of saturated fat—are aggregate sources of bioactive compounds. These compounds work as components in antioxidant systems, such as superoxide dismutases or glutathione peroxidase, and may break free radical chain reactions."
These results strongly indicated a healthy diet can form a significant part in reducing the risk of diseases associated with oxidative stress.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
On the finding a natural antioxidant ingredient or whole food for the prevention and treatment of the diseases associated with overexpression of free radical, researchers compared the antioxidant properties of banana (Musa paradisiaca) and Sapodilla/Chikoo (Manilkara zapota) peel extracts in chicken patties.
The chicken patties were assigned to 4 treatments viz., I. Control (meat + 2% salt), II.BHT (meat + 2% salt + 0.1% BHT), III. BPE (meat + 2% salt + 2% banana peel extract) and IV. SPE (meat + 2% salt + 2% sapodilla/chikoo peel extract).
By comparing the changes in color and lipid oxidation during 8 days refrigerated storage (4 ± °C) in 4 groups, researchers showed that
* The average phenolic content was 550.2 and 550.8 mg gallic acid equivalent per 10 g peel in BPE and SPE respectively.
* Free radical scavenging activity was 66.9 and 67.8% in BPE and SPE respectively.
* Banana peel extract had significantly (P < 0.05) higher reducing activity (1.6) as compared to sapodilla peel extract (0.91).
* Observation on lipid oxidation showed a significantly (P < 0.05) higher TBARS values used for the determination of oxidative stress in control than other three treatments.
* The increase in TBARS from the initial day of storage to last day of storage was highest in control (514.3%)compared to BHT (387.7%), BPE (370.6%) and SPE (383.7%). Both synthetic antioxidants and natural extracts significantly decreased the TBARS.
These results clearly suggested that the water extracts obtained from banana and sapodilla peel process natural antioxidants in poultry meat and meat products.
Furthermore, in examining the antioxidant activity of different Musa sp. leave extracts of hexane, ethyl acetate, and methanol, researchers found that
* All the Musa sp. extracts showed moderate antibacterial activities expect Musa paradisiaca with the inhibition zone ranging from 8.0 to 18.6 mm.
* Among four species ethyl acetate extracts of Musa paradisiaca showed the highest activity against tested pathogens particularly E. coli, P. aeruginosa, and Citrobacter sp.
* The minimum inhibitory concentrations were within the value of 15.63- 250 µg/mL and minimum bactericidal concentrations were ranging from 31.25- 250 µg/mL.
* Antioxidant activity of Musa acuminate exhibited maximum activity among other three Musa species.
Taken altogether, banana may be considered a functional remedy for the prevention and treatment of bacterial infections and diseases associated with oxidative stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Comparative antioxidant effect of BHT and water extracts of banana and sapodilla peels in raw poultry meat by Devatkal SK, Kumboj R, Paul D.(PubMed)
(2) Antibacterial and antioxidant activities of Musa sp. leaf extracts against multidrug resistant clinical pathogens causing nosocomial infection by Karuppiah P1, Mustaffa M.(PubMed)
(3) Healthy Dietary Patterns and Oxidative Stress as Measured by Fluorescent Oxidation Products in Nurses’ Health Study by Seungyoun Jung,1,2,3,* Stephanie A. Smith-Warner,1,2 Walter C. Willett,1,2,4 Molin Wang,2Tianying Wu,5 Majken Jensen,2,4 Susan E. Hankinson,4,6 and A. Heather Eliassen. (PMC)
Oxidative stress is a condition of imbalance of the ration of free radicals and antioxidant enzymes produced by the body, leading to the damage of cell, protein, and alternation of cell DNA.
The causes of oxidative are either associated with overexpression of free radicals and depressed the host antioxidant enzymes.
Free radicals are highly reactive molecules with the unpaired electron on the outer ring of the atom. In order for them to become balanced, they must donate or steal an electron from the stable molecules, leading to the chain of reaction which can not be stopped until the electrons on the outer ring are paired or inhibited by antioxidants.
This chain of domino's effect is known as oxidation.
Antioxidants are the stable molecules which inhibit oxidation.
There are 2 types of antioxidant in the human body. The antioxidants are produced by the host and antioxidant come from dietary sources.
Every day, our body is bombarded by the invasion of free radical. Believe or not, substances include fried foods, alcohol, tobacco smoke, pesticides, air pollutants, can produce harmful free radicals to our body.
Epidemiological studies agreed that oxidative stress is involved in several age-related conditions, including cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, neurodegenerative diseases, and cancer.
Dr. Seungyoun Jung,, the lead scientists in the evaluation of a healthy diet pattern and the risk of oxidative stress suggested, "Foods rich in healthy diets—characterized by a high intake of fruit, vegetables, and whole grains as well as a low intake of saturated fat—are aggregate sources of bioactive compounds. These compounds work as components in antioxidant systems, such as superoxide dismutases or glutathione peroxidase, and may break free radical chain reactions."
These results strongly indicated a healthy diet can form a significant part in reducing the risk of diseases associated with oxidative stress.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
On the finding a natural antioxidant ingredient or whole food for the prevention and treatment of the diseases associated with overexpression of free radical, researchers compared the antioxidant properties of banana (Musa paradisiaca) and Sapodilla/Chikoo (Manilkara zapota) peel extracts in chicken patties.
The chicken patties were assigned to 4 treatments viz., I. Control (meat + 2% salt), II.BHT (meat + 2% salt + 0.1% BHT), III. BPE (meat + 2% salt + 2% banana peel extract) and IV. SPE (meat + 2% salt + 2% sapodilla/chikoo peel extract).
By comparing the changes in color and lipid oxidation during 8 days refrigerated storage (4 ± °C) in 4 groups, researchers showed that
* The average phenolic content was 550.2 and 550.8 mg gallic acid equivalent per 10 g peel in BPE and SPE respectively.
* Free radical scavenging activity was 66.9 and 67.8% in BPE and SPE respectively.
* Banana peel extract had significantly (P < 0.05) higher reducing activity (1.6) as compared to sapodilla peel extract (0.91).
* Observation on lipid oxidation showed a significantly (P < 0.05) higher TBARS values used for the determination of oxidative stress in control than other three treatments.
* The increase in TBARS from the initial day of storage to last day of storage was highest in control (514.3%)compared to BHT (387.7%), BPE (370.6%) and SPE (383.7%). Both synthetic antioxidants and natural extracts significantly decreased the TBARS.
These results clearly suggested that the water extracts obtained from banana and sapodilla peel process natural antioxidants in poultry meat and meat products.
Furthermore, in examining the antioxidant activity of different Musa sp. leave extracts of hexane, ethyl acetate, and methanol, researchers found that
* All the Musa sp. extracts showed moderate antibacterial activities expect Musa paradisiaca with the inhibition zone ranging from 8.0 to 18.6 mm.
* Among four species ethyl acetate extracts of Musa paradisiaca showed the highest activity against tested pathogens particularly E. coli, P. aeruginosa, and Citrobacter sp.
* The minimum inhibitory concentrations were within the value of 15.63- 250 µg/mL and minimum bactericidal concentrations were ranging from 31.25- 250 µg/mL.
* Antioxidant activity of Musa acuminate exhibited maximum activity among other three Musa species.
Taken altogether, banana may be considered a functional remedy for the prevention and treatment of bacterial infections and diseases associated with oxidative stress.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Comparative antioxidant effect of BHT and water extracts of banana and sapodilla peels in raw poultry meat by Devatkal SK, Kumboj R, Paul D.(PubMed)
(2) Antibacterial and antioxidant activities of Musa sp. leaf extracts against multidrug resistant clinical pathogens causing nosocomial infection by Karuppiah P1, Mustaffa M.(PubMed)
(3) Healthy Dietary Patterns and Oxidative Stress as Measured by Fluorescent Oxidation Products in Nurses’ Health Study by Seungyoun Jung,1,2,3,* Stephanie A. Smith-Warner,1,2 Walter C. Willett,1,2,4 Molin Wang,2Tianying Wu,5 Majken Jensen,2,4 Susan E. Hankinson,4,6 and A. Heather Eliassen. (PMC)
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