The colon or large intestine formed part of the digestive system plays a critical role to remove waste products from your body.
In other words, the colon works alongside with other digestive organs to remove stool and maintain your fluid and electrolyte balance.
The colon begins at the end of the small intestine and ends at the rectum.
More precisely, the large intestine can be broken into six sections including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum.
Colon cancer is a medical condition caused by irregular cell growth in the cells on the surface of the inner lining of the colon tissues. At the early stage, most patients are assymptomatic.
Colon cancer can be classified depending on the location and cells origination
* Adenocarcinomas
Most cases of colon cancer are adenocarcinomas, originated in epithelium tissues, including the surface layer of skin, glands and their tissues that line the cavities and organs of the body.
* Squamous cell cancers
Squamous cells are the skin like cells that make up the colon lining together with the gland cells. Squamous cell cancers are rare with the risk of 25 per 100000.
Other colon tumors
* Carcinoid
Carcinoid is an unusual type of slow growth neuroendocrine tumor. It looks benign but might spread to other parts of the body as they grow in hormone-producing tissue in the digestive system.
* Leiomyosarcomas
Leiomyosarcomas are the rare and resistant types of colon cancer and generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Melanomas
Melanomas are a rare malignant tumor of cells that produce the dark pigment. This type of colon cancer usually originates from somewhere else before spreading to the colon.
According to the statistic provided by the American Cancer Society, in 2019, approximately, 101,420 new cases of colon cancer will be diagnosed in the US. The risk of colon cancer is slightly lower in women than in men.
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix.
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colon cancer, researchers investigated the antiproliferative activity of carotenoids separated from marine Chlorella ellipsoidea and freshwater Chlorella vulgaris on colon cancer cell line.
Based on the chemical analysis, the carotenoid from C. vulgaris was almost completely composed of lutein compared to carotenoid from C. ellipsoidea that was composed of violaxanthin with two minor xanthophylls, antheraxanthin, and zeaxanthin.
According to the tested assays, both semipurified extracts of C. ellipsoidea and C. vulgaris inhibited HCT116 cell growth in a dose-dependent manner, with the effective IC(50) values of 40.73 +/- 3.71 and 40.31 +/- 4.43 microg/mL, respectively.
In other words, both carotenoids even with different major chemical compound exerted a similar inhibitory activity in the tested cancer cell line.
Furthermore, both extracts also demonstrated a significant effect on inducing cancer cell apoptosis. However, C. ellipsoidea extract produced an apoptosis-inducing effect almost 2.5 times stronger than that of the C. vulgaris extract.
The results strongly suggested that there must be other unknown compounds found in C. ellipsoidea extract but not in C. vulgaris that causes the additional death of the cancer cell population.
Dr. Cha KH, the lead scientist after taking other factors into account wrote, "These results indicate that bioactive xanthophylls of C. ellipsoidea might be useful functional ingredients in the prevention of human cancers".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colon cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
(2) Bowel (Colorectal ) Cancer by Kyle J. Norton
Sunday, July 7, 2019
Saturday, July 6, 2019
Green tea, The best Beverage for Lower Coronary Artery Disease Risk
A recent study conducted by a respectable institute suggested that green tea may have a potential effect on reduced risk and treatment of coronary artery disease.
Coronary artery disease is a condition of narrowing coronary arteries, caused by hardening arterial wall, cholesterol building up in the arteries, leading to blockage of the blood flow in the arteries.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick of neutralization.
According to the review of literature of a study of 22 healthy volunteers, injection of green tea 7 cups/day exhibited anti cholesterol effects through modifying the low-density lipoprotein (MDA-LDL) concentrations and decreasing plasma C-reactive protein and interleukin (IL)-6 concentrations involving inflammatory expression.
Green tea consumption of less of 1 cup a day in 725 patients undergoing coronary angiography, is found to associate to lower risk of myocardial infarction (MI) in compared to CVD patients without MI and patients without CAD.
Dr. Ohmori R, the lead author said," Green tea consumption was found to be inversely associated with MI in Japanese patients" and " The protective effect of green tea against atherosclerosis is more likely to be because of the inhibitory effect of LDL oxidation than because of anti-inflammatory effect".
Additionally, the Japanese population with a green tea drinking habit, showed a significantly reduced risk of a decreased incidence of coronary artery disease (CAD), due to the presence of abundant polyphenolic antioxidants.
In a group of comprised 203 patients who underwent coronary angiography (109 patients with significant coronary stenosis and 94 patients without), coronary artery disease (CAD) is associated inversely in regular green tea drinking group.
The study showed that green tea intake per day was an independent predictor for CVD based on a multivariate logistic regression analysis. but not a predictor of cardiovascular diseases based on the Cox proportional hazard model.
Continuously, in researching the data of PUBMED and EMBASE for studies conducted from 1966 through November 2009 filed the following results:
1. 5 studies on green tea. indicated the lower relative risk is depended significantly between the highest green tea consumption and reduced risk of CVD.
2. The risk of CVD is reduced by 10% for every additional cup of green tea intake.
Taking together, green tea may be used as a functional food of healthy adults with a higher risk CVD.
However, long term and a large amount of green tea consumption should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antioxidant beverages: green tea intake and coronary artery disease by Ohmori R1, Kondo K2, Momiyama Y3.(PubMed)
(2) Effects of green tea intake on the development of coronary artery disease by Sano J1, Inami S, Seimiya K, Ohba T, Sakai S, Takano T, Mizuno K.(PubMed)
Coronary artery disease is a condition of narrowing coronary arteries, caused by hardening arterial wall, cholesterol building up in the arteries, leading to blockage of the blood flow in the arteries.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick of neutralization.
According to the review of literature of a study of 22 healthy volunteers, injection of green tea 7 cups/day exhibited anti cholesterol effects through modifying the low-density lipoprotein (MDA-LDL) concentrations and decreasing plasma C-reactive protein and interleukin (IL)-6 concentrations involving inflammatory expression.
Green tea consumption of less of 1 cup a day in 725 patients undergoing coronary angiography, is found to associate to lower risk of myocardial infarction (MI) in compared to CVD patients without MI and patients without CAD.
Dr. Ohmori R, the lead author said," Green tea consumption was found to be inversely associated with MI in Japanese patients" and " The protective effect of green tea against atherosclerosis is more likely to be because of the inhibitory effect of LDL oxidation than because of anti-inflammatory effect".
Additionally, the Japanese population with a green tea drinking habit, showed a significantly reduced risk of a decreased incidence of coronary artery disease (CAD), due to the presence of abundant polyphenolic antioxidants.
In a group of comprised 203 patients who underwent coronary angiography (109 patients with significant coronary stenosis and 94 patients without), coronary artery disease (CAD) is associated inversely in regular green tea drinking group.
The study showed that green tea intake per day was an independent predictor for CVD based on a multivariate logistic regression analysis. but not a predictor of cardiovascular diseases based on the Cox proportional hazard model.
Continuously, in researching the data of PUBMED and EMBASE for studies conducted from 1966 through November 2009 filed the following results:
1. 5 studies on green tea. indicated the lower relative risk is depended significantly between the highest green tea consumption and reduced risk of CVD.
2. The risk of CVD is reduced by 10% for every additional cup of green tea intake.
Taking together, green tea may be used as a functional food of healthy adults with a higher risk CVD.
However, long term and a large amount of green tea consumption should be taken with care to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antioxidant beverages: green tea intake and coronary artery disease by Ohmori R1, Kondo K2, Momiyama Y3.(PubMed)
(2) Effects of green tea intake on the development of coronary artery disease by Sano J1, Inami S, Seimiya K, Ohba T, Sakai S, Takano T, Mizuno K.(PubMed)
Herbal Turmeric Suppresses Osteoarthritis
Osteoarthritis (OA) one of the most common forms of arthritis that affects over 25 25 million people in the United States is a chronic inflammatory disease of the joints due to wear and tear over time.
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty of moving the joint or joints. The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest.
Conventionally, treatment of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.
Most common risk factors associated with the onset of OA include genetic preposition, being overweight or obese, previous joint injury and repetitive movements or injuries to joints (such as a fracture, surgery or ligament tears).
However, most people with some of the risk factors have never developed the disease.
Dr. Sally Thomas, the lead scientist in the treatment of OA patients wrote, "As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition".
And, "For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes, and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol together with clinical effects in statin users suggests a potential benefit of reduction of cholesterol by dietary means".
In other words, depending on the causes, patients may be recommended to a specific treatment.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of osteoarthritis (OA), researchers examined the Curene®, a bioavailable formulation of turmeric anti-inflammatory properties.
The randomized, double-blind, placebo-controlled, parallel-group included 50 subjects aged between 40 and 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months according to American College of Rheumatology (ACR) criteria.
The treatment group received 500mg Curene® once daily and the other group received a placebo.
According to the results from the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Curene® treated group showed a statistically significant reduction of pain score compared to placebo without inducing any adverse effects.
In other words, Curene® 500mg not only reduced pain, stiffness but also improved physical functioning in subjects suffering from knee OA.
In order to reveal more information of turmeric anti OA activity, researchers investigated LI73014F2 is a novel composition prepared from extracts of Terminalia chebula fruit, Curcuma longa rhizome, and Boswellia serrata gum resin in the inhibition of 5-Lipoxygenase (5-LOX).
Where activated enzyme 5-Lipoxygenase (5-LOX), has been found to induce pain in patients with OA.
In a 90-day randomized, placebo-controlled double-blind study included 105 particpants divded into three groups: placebo (n = 35), 200 mg/day of LI73014F2 (n = 35), and 400 mg/day of LI73014F2 (n = 35).
According to the results from tested assays obtained from the baseline (day 0) and on day 14 ± 3, 30 ± 3, 60 ± 3, and at the end of the study (day 90 ± 3), all doses of LI73014F2 conferred a strong effect in pain relief, improved physical function, and quality of life in OA patients, compared to the baseline.
Dr. Karlapudi V, the lead scientist said, "preclinical and clinical data together strongly suggest that the herbal formulation LI73014F2 is a safe and effective intervention for management of joint discomfort, demonstrating efficacy as early as 14 days".
Based on the findings, turmeric processed a high amount of bioactive curcumin used alone or combined with other herbal medicines may be considered supplements for the treatment of osteoarthritis (OA), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
Osteoarthritis
(1) A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA by Panda SK1, Nirvanashetty S2, Parachur VA3, Mohanty N4, Swain T. (PubMed)
(2) A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee by Karlapudi V1, Prasad Mungara AVV2, Sengupta K3, Davis BA4, Raychaudhuri SP. (PubMed)
(3) What is the evidence for a role for diet and nutrition in osteoarthritis? by Sally Thomas,1 Heather Browne,1 Ali Mobasheri,2,3,4 and Margaret P Rayman. (PMC)
The characteristics of osteoarthritis are aching pain, stiffness, or difficulty of moving the joint or joints. The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest.
Conventionally, treatment of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.
Most common risk factors associated with the onset of OA include genetic preposition, being overweight or obese, previous joint injury and repetitive movements or injuries to joints (such as a fracture, surgery or ligament tears).
However, most people with some of the risk factors have never developed the disease.
Dr. Sally Thomas, the lead scientist in the treatment of OA patients wrote, "As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition".
And, "For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes, and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol together with clinical effects in statin users suggests a potential benefit of reduction of cholesterol by dietary means".
In other words, depending on the causes, patients may be recommended to a specific treatment.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of osteoarthritis (OA), researchers examined the Curene®, a bioavailable formulation of turmeric anti-inflammatory properties.
The randomized, double-blind, placebo-controlled, parallel-group included 50 subjects aged between 40 and 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months according to American College of Rheumatology (ACR) criteria.
The treatment group received 500mg Curene® once daily and the other group received a placebo.
According to the results from the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Curene® treated group showed a statistically significant reduction of pain score compared to placebo without inducing any adverse effects.
In other words, Curene® 500mg not only reduced pain, stiffness but also improved physical functioning in subjects suffering from knee OA.
In order to reveal more information of turmeric anti OA activity, researchers investigated LI73014F2 is a novel composition prepared from extracts of Terminalia chebula fruit, Curcuma longa rhizome, and Boswellia serrata gum resin in the inhibition of 5-Lipoxygenase (5-LOX).
Where activated enzyme 5-Lipoxygenase (5-LOX), has been found to induce pain in patients with OA.
In a 90-day randomized, placebo-controlled double-blind study included 105 particpants divded into three groups: placebo (n = 35), 200 mg/day of LI73014F2 (n = 35), and 400 mg/day of LI73014F2 (n = 35).
According to the results from tested assays obtained from the baseline (day 0) and on day 14 ± 3, 30 ± 3, 60 ± 3, and at the end of the study (day 90 ± 3), all doses of LI73014F2 conferred a strong effect in pain relief, improved physical function, and quality of life in OA patients, compared to the baseline.
Dr. Karlapudi V, the lead scientist said, "preclinical and clinical data together strongly suggest that the herbal formulation LI73014F2 is a safe and effective intervention for management of joint discomfort, demonstrating efficacy as early as 14 days".
Based on the findings, turmeric processed a high amount of bioactive curcumin used alone or combined with other herbal medicines may be considered supplements for the treatment of osteoarthritis (OA), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
Osteoarthritis
(1) A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA by Panda SK1, Nirvanashetty S2, Parachur VA3, Mohanty N4, Swain T. (PubMed)
(2) A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee by Karlapudi V1, Prasad Mungara AVV2, Sengupta K3, Davis BA4, Raychaudhuri SP. (PubMed)
(3) What is the evidence for a role for diet and nutrition in osteoarthritis? by Sally Thomas,1 Heather Browne,1 Ali Mobasheri,2,3,4 and Margaret P Rayman. (PMC)
Friday, July 5, 2019
Green Tea, Reduced risk of Early onset and Progression of Cognitive Impairment
Green tea injection is associated with a reduced risk of age-related cognitive decline, a recent study postulated.
Cognitive impairment is a condition of the decline of memory and thinking skills due to aging considered as an early sign of neurodegenerative diseases.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a piece of ginger will solve the problem.
In a total of 12 elderly nursing home residents with cognitive dysfunction, participants who drink green tea powder 2 g/day for 3 months showed a significantly improved cognitive performance and reduced the progression of cognitive dysfunction indicated by Mini-Mental State Examination Japanese version (MMSE-J) score.
Other study (Japanese residents aged >60 years from Nakajima, Japan (the Nakajima Project) of 723 participants with normal cognitive function at a baseline survey (2007-2008), the 490 completed the follow up survey in 2011-2013, suggested that incidence of dementia and cognitive impairment are lower among individuals who consumed green tea 1-6 days per week compared with individuals who did not consume green tea at all.
Additionally, according to the double-blind, randomized controlled study of 39 nursing home residents with cognitive dysfunction (four men, 29 women) divided into two groups either with
consumption of 2 g/day of green tea powder (containing 220.2 mg of catechins) or placebo powder (containing 0.0 mg of catechins), the green tea-treated group showed a significantly reduced cognitive dysfunction in 3 months follow up in compared to placebo.
The efficacy of green tea in decreased progression of cognitive impairment in the short term may be attributed to ameliorated oxidative stress and levels of low-density lipoprotein.
Taking together, Green tea may process potential in reduced risk of early onset and progression of cognitive decline in the aging population, but long term and large amount of injection should be taken with care.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea consumption affects cognitive dysfunction in the elderly: a pilot study by Ide K1, Yamada H2, Takuma N3, Park M4, Wakamiya N5, Nakase J6, Ukawa Y7, Sagesaka YM8.(PubMed)
(2) Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline by Noguchi-Shinohara M1, Yuki S1, Dohmoto C1, Ikeda Y1, Samuraki M1, Iwasa K1, Yokogawa M2, Asai K3, Komai K4, Nakamura H5,(PubMed)
(3) Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study by Ide K1, Yamada H2, Takuma N3, Kawasaki Y1, Harada S1, Nakase J4, Ukawa Y4, Sagesaka YM4.(PubMed)
Cognitive impairment is a condition of the decline of memory and thinking skills due to aging considered as an early sign of neurodegenerative diseases.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a piece of ginger will solve the problem.
In a total of 12 elderly nursing home residents with cognitive dysfunction, participants who drink green tea powder 2 g/day for 3 months showed a significantly improved cognitive performance and reduced the progression of cognitive dysfunction indicated by Mini-Mental State Examination Japanese version (MMSE-J) score.
Other study (Japanese residents aged >60 years from Nakajima, Japan (the Nakajima Project) of 723 participants with normal cognitive function at a baseline survey (2007-2008), the 490 completed the follow up survey in 2011-2013, suggested that incidence of dementia and cognitive impairment are lower among individuals who consumed green tea 1-6 days per week compared with individuals who did not consume green tea at all.
Additionally, according to the double-blind, randomized controlled study of 39 nursing home residents with cognitive dysfunction (four men, 29 women) divided into two groups either with
consumption of 2 g/day of green tea powder (containing 220.2 mg of catechins) or placebo powder (containing 0.0 mg of catechins), the green tea-treated group showed a significantly reduced cognitive dysfunction in 3 months follow up in compared to placebo.
The efficacy of green tea in decreased progression of cognitive impairment in the short term may be attributed to ameliorated oxidative stress and levels of low-density lipoprotein.
Taking together, Green tea may process potential in reduced risk of early onset and progression of cognitive decline in the aging population, but long term and large amount of injection should be taken with care.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea consumption affects cognitive dysfunction in the elderly: a pilot study by Ide K1, Yamada H2, Takuma N3, Park M4, Wakamiya N5, Nakase J6, Ukawa Y7, Sagesaka YM8.(PubMed)
(2) Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline by Noguchi-Shinohara M1, Yuki S1, Dohmoto C1, Ikeda Y1, Samuraki M1, Iwasa K1, Yokogawa M2, Asai K3, Komai K4, Nakamura H5,(PubMed)
(3) Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study by Ide K1, Yamada H2, Takuma N3, Kawasaki Y1, Harada S1, Nakase J4, Ukawa Y4, Sagesaka YM4.(PubMed)
Bilberry Protects the Blood Vessels Against the Risk of Vascular Disease in Vivo
Vasoprotection is the action in which substances including herbal and natural remedy are used to protect the integrity of the blood vessels.
Blood vessels are the tubular structure including a vein, artery, or capillary which carries the blood through the tissues and organs pumped by the heart.
There are 3 main types of blood vessel
* Arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body. Damage of arteries is found to induce coronary artery disease caused by narrowing or blockage of the coronary arteries due to plaques accumulated on the arterial wall.
* Veins that carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with disease of the veins that affects up to 20 percent of adults.
* Capillaries (the smallest blood vessels) has been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.
Some researchers suggested that following a healthy diet accompanied by moderate exercise may have a strong impact on the blood vessels integrity.
Dr. Hanrui Zhang said, "Accumulating evidence suggests that inflammatory cytokine tumor necrosis factor-alpha (TNFα) plays a pivotal role in the dysregulation of macrovascular and microvascular function".
And, "Dietary supplements and exercise training decrease TNFαproduction and ameliorate TNFα-mediated pathological changes in vasculature. Thus, the inhibitory effects of dietary supplements and physical exercise on TNFα production and TNFα signaling may contribute to their vasoprotective properties".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
On finding a natural ingredient which processes vasoactive and vasoprotective properties, researchers examined the effects of anthocyanin-rich extracts prepared from chokeberry (Ck), bilberry (B), or elderberry (E). on reactive oxygen species (ROS) play a critical role in the impairment of nitric oxide-mediated vascular functions.
In Coronary arterial rings isolated from 64 pigs and incubated in sterile tissue culture media overnight, Ck and B, but not E, produced dose- and endothelium-dependent vasorelaxation.
In coronary vascular tone, endothelium-dependent vasorelaxation by other factors was not affected by exposure of rings to any extract at 0.05 mg total anthocyanins per liter for 5 or 30 min.
Furthermore, anthocyanin-enhanced extracts produce endothelium-dependent relaxation in porcine coronary arteries.
However, high doses of B exerted a significantly protective effect against alternation of coronary arteries induced by ROS with no effect on vasorelaxation to endogenous or exogenous NO.
Based on the findings, researchers wrote, "These results suggest that such extracts could have significant beneficial effects in vascular disease".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the prevention and treatment of vascular disease, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts by Bell DR1, Gochenaur K. (PubMed)
(2) Vasoprotection by Dietary Supplements and Exercise: Role of TNFα Signaling by Hanrui Zhang* and Cuihua Zhang. (PMC)
Blood vessels are the tubular structure including a vein, artery, or capillary which carries the blood through the tissues and organs pumped by the heart.
There are 3 main types of blood vessel
* Arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body. Damage of arteries is found to induce coronary artery disease caused by narrowing or blockage of the coronary arteries due to plaques accumulated on the arterial wall.
* Veins that carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with disease of the veins that affects up to 20 percent of adults.
* Capillaries (the smallest blood vessels) has been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.
Some researchers suggested that following a healthy diet accompanied by moderate exercise may have a strong impact on the blood vessels integrity.
Dr. Hanrui Zhang said, "Accumulating evidence suggests that inflammatory cytokine tumor necrosis factor-alpha (TNFα) plays a pivotal role in the dysregulation of macrovascular and microvascular function".
And, "Dietary supplements and exercise training decrease TNFαproduction and ameliorate TNFα-mediated pathological changes in vasculature. Thus, the inhibitory effects of dietary supplements and physical exercise on TNFα production and TNFα signaling may contribute to their vasoprotective properties".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
On finding a natural ingredient which processes vasoactive and vasoprotective properties, researchers examined the effects of anthocyanin-rich extracts prepared from chokeberry (Ck), bilberry (B), or elderberry (E). on reactive oxygen species (ROS) play a critical role in the impairment of nitric oxide-mediated vascular functions.
In Coronary arterial rings isolated from 64 pigs and incubated in sterile tissue culture media overnight, Ck and B, but not E, produced dose- and endothelium-dependent vasorelaxation.
In coronary vascular tone, endothelium-dependent vasorelaxation by other factors was not affected by exposure of rings to any extract at 0.05 mg total anthocyanins per liter for 5 or 30 min.
Furthermore, anthocyanin-enhanced extracts produce endothelium-dependent relaxation in porcine coronary arteries.
However, high doses of B exerted a significantly protective effect against alternation of coronary arteries induced by ROS with no effect on vasorelaxation to endogenous or exogenous NO.
Based on the findings, researchers wrote, "These results suggest that such extracts could have significant beneficial effects in vascular disease".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the prevention and treatment of vascular disease, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts by Bell DR1, Gochenaur K. (PubMed)
(2) Vasoprotection by Dietary Supplements and Exercise: Role of TNFα Signaling by Hanrui Zhang* and Cuihua Zhang. (PMC)
Thursday, July 4, 2019
Green tea, the Best in Prevention and Treatment of Chronic Inflammatory Diseases
Good news for people with chronic inflammatory diseases, green tea polyphenols (GrTPs) is found to reduced risk and progression of the diseases through the exhibition of potent antioxidants in regulating vital signaling pathways involved the production of inflammatory cytokines. a renowned institute study suggested
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger in each drink will attenuate the expression.
Chronic inflammation diseases are medical conditions caused by over reaction of the immune system in protection against microbial invasion and damage to organs due to injuring, affecting the tissue healing process, which can lead to life-long debilitation and loss of tissue function and organ failure.
According to the University of Kentucky Medical Center, green tea phytochemical polyphenols protected our body against inflammation through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innate anti-inflammatory cytokines.
In chronic Inflammatory Bowel Disease patients, catechin isolated from green tea enhanced the antioxidant production such as glutathione peroxidases (GPO) and glutathione (GSH), in significantly inhibited excessive oxidative stress through direct or indirect in reducing the oxidative damages to the colon.
Dr. Fan FY, the lead author said, " catechins can exert their significant anti-inflammatory properties by regulating the activation or deactivation of inflammation-related oxidative stress-related cell signaling pathways( involved proinflammation specifically)".
Particularly, the study also specified, the impression of antioxidant catechin in stabilized the structure of the gastrointestinal micro-ecological environment via promoting the proliferation of beneficial intestinal bacteria and regulating the balance of intestinal flora for induction of relief in patients with IBD.
Furthermore, in a psoriasis mouse model, BALB/c mice topically treated with IMQ for 6 consecutive days, displayed a significant alleviated psoriasiform dermatitis, improved the skin pathological structure by reducing the expression of epidermal PCNA(Base cells) and promoted the expression of caspase-14 involved in inflammation.
In fact, according to the study, the efficacy of Epigallocatechin-3-gallate (EGCG), for treatment of
psoriasis-like inflammation is the result of the phytochemical functions in anti-inflammatory, immune regulatory and antioxidant activation.
Taking together, green tea may be used as a protectively functional food in the prevention and treatment of chronic inflammatory diseases, but regularly large amount injection should be avoided to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)
(2) Catechins and Their Therapeutic Benefits to Inflammatory Bowel Disease by Fan FY1, Sang LX2, Jiang M3.(PubMed)
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger in each drink will attenuate the expression.
Chronic inflammation diseases are medical conditions caused by over reaction of the immune system in protection against microbial invasion and damage to organs due to injuring, affecting the tissue healing process, which can lead to life-long debilitation and loss of tissue function and organ failure.
According to the University of Kentucky Medical Center, green tea phytochemical polyphenols protected our body against inflammation through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innate anti-inflammatory cytokines.
In chronic Inflammatory Bowel Disease patients, catechin isolated from green tea enhanced the antioxidant production such as glutathione peroxidases (GPO) and glutathione (GSH), in significantly inhibited excessive oxidative stress through direct or indirect in reducing the oxidative damages to the colon.
Dr. Fan FY, the lead author said, " catechins can exert their significant anti-inflammatory properties by regulating the activation or deactivation of inflammation-related oxidative stress-related cell signaling pathways( involved proinflammation specifically)".
Particularly, the study also specified, the impression of antioxidant catechin in stabilized the structure of the gastrointestinal micro-ecological environment via promoting the proliferation of beneficial intestinal bacteria and regulating the balance of intestinal flora for induction of relief in patients with IBD.
Furthermore, in a psoriasis mouse model, BALB/c mice topically treated with IMQ for 6 consecutive days, displayed a significant alleviated psoriasiform dermatitis, improved the skin pathological structure by reducing the expression of epidermal PCNA(Base cells) and promoted the expression of caspase-14 involved in inflammation.
In fact, according to the study, the efficacy of Epigallocatechin-3-gallate (EGCG), for treatment of
psoriasis-like inflammation is the result of the phytochemical functions in anti-inflammatory, immune regulatory and antioxidant activation.
Taking together, green tea may be used as a protectively functional food in the prevention and treatment of chronic inflammatory diseases, but regularly large amount injection should be avoided to prevent toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)
(2) Catechins and Their Therapeutic Benefits to Inflammatory Bowel Disease by Fan FY1, Sang LX2, Jiang M3.(PubMed)
Turmeric Protects the Kidney Against Renal Dysfunction
Renal protection is strategies that protect the kidney against injury or damage. In other words, renal protection is a process that maintains the function of the kidneys.
Kidneys, a pair of the bean-shaped organ in the human body only filters out blood but also balances the body fluids by eliminating them and remove them through urinary secretion.
Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness
In severe cases, patients may also have symptoms of shortness of breath, confusion, and irregular heartbeat.
The worse cases of kidney damage can lead to renal failure, a condition that induces wastes and toxins accumulated in the blood. In this stage, dialysis and kidney transplant are the only options.
Kidney damage can be classified into 4 different stages
* Stage 1 with normal or high GFR (GFR > 90 mL/min). In this stage of kidney patients are assymptomatic.
* Stage 2 Mild CKD (GFR = 60-89 mL/min), Patients in this stage also experience no symptoms.
*Stage 3A Moderate CKD (GFR = 45-59 mL/min) and 3B moderate CKD (GFR = 30-44 mL/min.
Most patients are assymptomatic. However, some patients may experience symptoms of mild swelling in the hands and feet, back pain and urinating more or less than normal.
* Stage 4 CKD (GFR = 15-30 mL/min). Most patients in this stage experience more severe symptoms of swelling in the hands and feet, back pain and urinating more or less than normal, accompanied by other health problem associated with weakened kidney function
* Stage 5 EndStage CKD (GFR <15 mL/min). Patients at this advanced stage are very close to renal failure or renal failure. Symptoms are getting worse.
Where eGFR is short for estimated glomerular filtration rate.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential compound with the kidney protective effect against the side effects of Cisplatin, researchers investigated the protective effect and mechanism of tetrahydrocurcumin on cisplatin-induced kidney damage.
The study included selected rats treated by Tetrahydrocurcumin orally every day at a dose of 80 mg/kg body weight for ten days, and a single dose of cisplatin was administered intraperitoneally (7.5 mg/kg body weight) in 0.9 % saline on day four.
According to the tested assays, Cisplatin-induced renal cell damage was significantly reduced by tetrahydrocurcumin treatment.
Tetrahydrocurcumin also suppressed the cisplatin-treated rat in inducing overexpression of the creatinine clearance levels, an indication of kidney dysfunction.
Proinflammatory protein associated with increased oxidative stress in the kidney caused by cancer medicine was also inhibited by tetrahydrocurcumin administration during the experiment.
After taking into account co and confounders, the researcher wrote, "collectively provide therapeutic evidence that tetrahydrocurcumin ameliorates renal damage by regulating inflammation and apoptosis".
In order to reveal more information about turmeric renal protective activity, researchers evaluated the intervening effects of Curcuma aromatica oil on renal interstitial fibrosis rats induced by unilateral ureteral obstruction.
The study included infected rats treated with Curcuma aromatica oil on 3, 7, 14, and 28 days.
According to the Nuclear magnetic resonance (NMR)-based metabonomics combined with clinical chemistry and histopathology examination, Curcuma aromatica oil demonstrated strong kidney protection by inhibiting some metabolic pathways associated with the onset of renal interstitial fibrosis, including lipids metabolism, glycolysis, and methylamine metabolism,
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the protection of kidneys, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective effect of tetrahydrocurcumin against cisplatin-induced renal damage: in vitro and in vivo studies by Song KI1, Park JY2, Lee S3, Lee D2, Jang HJ4, Kim SN3, Ko H5, Kim HY6, Lee JW3, Hwang GS2, Kang KS2, Yamabe N. (PubMed)
(2) Serum metabonomic analysis of protective effects of Curcuma aromatica oil on renal fibrosis rats by Zhao L1, Zhang H1, Yang Y2, Zheng Y1, Dong M1, Wang Y1, Bai G3, Ye X3, Yan Z3, Gao H. (PubMed)
Kidneys, a pair of the bean-shaped organ in the human body only filters out blood but also balances the body fluids by eliminating them and remove them through urinary secretion.
Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness
In severe cases, patients may also have symptoms of shortness of breath, confusion, and irregular heartbeat.
The worse cases of kidney damage can lead to renal failure, a condition that induces wastes and toxins accumulated in the blood. In this stage, dialysis and kidney transplant are the only options.
Kidney damage can be classified into 4 different stages
* Stage 1 with normal or high GFR (GFR > 90 mL/min). In this stage of kidney patients are assymptomatic.
* Stage 2 Mild CKD (GFR = 60-89 mL/min), Patients in this stage also experience no symptoms.
*Stage 3A Moderate CKD (GFR = 45-59 mL/min) and 3B moderate CKD (GFR = 30-44 mL/min.
Most patients are assymptomatic. However, some patients may experience symptoms of mild swelling in the hands and feet, back pain and urinating more or less than normal.
* Stage 4 CKD (GFR = 15-30 mL/min). Most patients in this stage experience more severe symptoms of swelling in the hands and feet, back pain and urinating more or less than normal, accompanied by other health problem associated with weakened kidney function
* Stage 5 EndStage CKD (GFR <15 mL/min). Patients at this advanced stage are very close to renal failure or renal failure. Symptoms are getting worse.
Where eGFR is short for estimated glomerular filtration rate.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential compound with the kidney protective effect against the side effects of Cisplatin, researchers investigated the protective effect and mechanism of tetrahydrocurcumin on cisplatin-induced kidney damage.
The study included selected rats treated by Tetrahydrocurcumin orally every day at a dose of 80 mg/kg body weight for ten days, and a single dose of cisplatin was administered intraperitoneally (7.5 mg/kg body weight) in 0.9 % saline on day four.
According to the tested assays, Cisplatin-induced renal cell damage was significantly reduced by tetrahydrocurcumin treatment.
Tetrahydrocurcumin also suppressed the cisplatin-treated rat in inducing overexpression of the creatinine clearance levels, an indication of kidney dysfunction.
Proinflammatory protein associated with increased oxidative stress in the kidney caused by cancer medicine was also inhibited by tetrahydrocurcumin administration during the experiment.
After taking into account co and confounders, the researcher wrote, "collectively provide therapeutic evidence that tetrahydrocurcumin ameliorates renal damage by regulating inflammation and apoptosis".
In order to reveal more information about turmeric renal protective activity, researchers evaluated the intervening effects of Curcuma aromatica oil on renal interstitial fibrosis rats induced by unilateral ureteral obstruction.
The study included infected rats treated with Curcuma aromatica oil on 3, 7, 14, and 28 days.
According to the Nuclear magnetic resonance (NMR)-based metabonomics combined with clinical chemistry and histopathology examination, Curcuma aromatica oil demonstrated strong kidney protection by inhibiting some metabolic pathways associated with the onset of renal interstitial fibrosis, including lipids metabolism, glycolysis, and methylamine metabolism,
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the protection of kidneys, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective effect of tetrahydrocurcumin against cisplatin-induced renal damage: in vitro and in vivo studies by Song KI1, Park JY2, Lee S3, Lee D2, Jang HJ4, Kim SN3, Ko H5, Kim HY6, Lee JW3, Hwang GS2, Kang KS2, Yamabe N. (PubMed)
(2) Serum metabonomic analysis of protective effects of Curcuma aromatica oil on renal fibrosis rats by Zhao L1, Zhang H1, Yang Y2, Zheng Y1, Dong M1, Wang Y1, Bai G3, Ye X3, Yan Z3, Gao H. (PubMed)
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