Cancer is a class of diseases associated with irregular cell growth in the tissue of organs.
The colon-rectum formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is cancer located in the colon or rectum caused alternation of cell DNA. Most cases of colorectal cancer begin in the cells on the surface of inner ling tissue in either the colon or rectum, before multiplying to form a tumor.
Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.
According to the statistics provided by the American Cancer Society, in the US,
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in 2019.
Additionally, colorectal cancer will also cause the death of 51,020 Americans in 2019.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
Besides adenocarcinomas, the common type of colorectal cancer originated in epithelium tissues and squamous cells that make up the bowel lining together with the gland cells, other types of colorectal tumors include
* Carcinoid
Carcinoid is an unusual type of slow growth neuroendocrine tumor in the hormone-producing tissue in the digestive system. the condition may look benign but can spread to other parts of the body as they grow
* Leiomyosarcomas
Leiomyosarcomas are the rare and resistant types of colorectal cancer and generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Lymphomas
Bowel lymphomas are rare and more likely to start in the rectum rather in the colon. Many patients with lymphomas are diagnosed in the late stage and already spread to other organs.
* Melanomas
Melanomas are a rare malignant tumor of cells that produce the dark pigment. This type of bowel cancer usually originates from somewhere else and then spread to the bowel.
Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colorectal cancer, researchers investigated whether dietary lutein/zeaxanthin, the major compounds found in carotenoid intake affect colorectal cancer risk in patients with a DICER1 rs3742330 polymorphism.
The experiment included 923 colorectal cancer patients and 1,846 controls based on eligibility criteria, that answered the semiquantitative food frequency questionnaire and the DICER1 rs3742330 genotype.
Based on the returned questionnaire differentiation, the highest quartile of lutein/zeaxanthin consumption was inversely associated with colorectal cancer risk.
In genotype analysis, patients who carry G allele (AG + GG) showed a significantly reduced colorectal cancer incidence compared to that of AA carriers.
Furthermore, patients with G allele (AG + GG) along with high lutein/zeaxanthin consumption were markedly associated with a decreased colorectal cancer risk, particularly in rectal cancer compared to that of AA carriers with low lutein/zeaxanthin intakes.
The results strongly suggested that carotenoids major compounds lutein/zeaxanthin has a strong implication on the colorectal cancer risk in patients with DICER1 rs3742330 genotype.
Dr. Kim J, the lead scientist after taking into account co and confounders wrote in the final report, " colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colorectal cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
Rectal cancer
(1) (1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A > G Polymorphism Relative to Colorectal Cancer Risk by Kim J1, Lee J1, Oh JH2, Chang HJ2, Sohn DK2, Kwon O3, Shin A4, Kim J. (PubMed)
(3) Bowel (Colorectal ) Cancer by Kyle J. Norton
Monday, October 7, 2019
Green Tea, A Potent Ingredient in Inhibited Athlete's Foot (Tinea Pedis)
Green tea may have a therapeutic and positive effect in reduced risk and and treatment of athlete's foot( tinea pedis,), some scientists suggested.
The results of the investigation were reported by several institutes, including the Tokyo Medical and Dental University and published online at medical literature.
Green tea is a precious drink processed a number of health benefits known to almost everyone in Asia and the Western world.
Athlete's foot( tinea pedis) is a common skin disease characterized by a fungal infection.
Uncontrolled proliferation of yeast-fungi not only produces pungent odor but also facilitates the risks of small vesicles, fissures, scaling, and maceration.
Green tea is not one of the favorite natural ingredient used for treatment of athlete's foot (tinea pedis) in compared to the formula of aromatic oil powder-compound consisting of arrowroot, baking soda, basil oil, tea tree oil, sage oil, and clove oil which has been proven effective in 48 hours injection with enclosed feet in shoes and socks.
In the reaffirmed green tea polyphenols (GTP) in inhibited Trichophyton in vitro, researchers at the Tokyo Medical and Dental University launched an evaluation of the effects of GTP on interdigital tinea pedis in a total of 94 infected patients.
The enrolled patients were assigned either to a lukewarm water foot bath containing GTP(0.1% green tea polyphenol solution: 89.5% catechins) or placebo.
The foot baths were given once daily with feet cleaned with mild soap and rinsed with warm water before submerging into the warm GTP foot bath for 15 minutes up to the ankles.
Patients were also given instruction not to dry off the liquids after 15 minutes to ensure further skin penetration of green tea concentration.
At the end of 12 experiments, researchers found that either GTP or placebo exerted a significant reduction in the size of the affected area, the recurrence rate, and the microscopy findings.
In the overall assessment, after taking into account other co and confounders, the green tea treatment group demonstrated significant improvements compared to the placebo group.
These results suggested that green tea (GTP) may process a strong antifungal activity in reduced the symptoms expression of an athlete's foot (tinea pedis), including redness, skin peeling, softening of the tissue.
Therefore, people with long term of athlete's foot (tinea pedis) may be beneficiary by applying the extract in practical use without inducing any adverse effects.
Taken together, green tea polyphenols may be considered as a natural treatment of athlete's foot (tinea pedis), however, due to the small sample size, researchers suggested that large sample size and multi centers investigation are necessary to reaffirm this viability.
Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Effects of a foot bath containing green tea polyphenols on interdigital tinea pedis by Ikeda S1, Kanoya Y, Nagata S.(PubMed)
(2) Athlete’s Foot (tinea pedis) by Centers for Disease Control and Prevention
The results of the investigation were reported by several institutes, including the Tokyo Medical and Dental University and published online at medical literature.
Green tea is a precious drink processed a number of health benefits known to almost everyone in Asia and the Western world.
Athlete's foot( tinea pedis) is a common skin disease characterized by a fungal infection.
Uncontrolled proliferation of yeast-fungi not only produces pungent odor but also facilitates the risks of small vesicles, fissures, scaling, and maceration.
Green tea is not one of the favorite natural ingredient used for treatment of athlete's foot (tinea pedis) in compared to the formula of aromatic oil powder-compound consisting of arrowroot, baking soda, basil oil, tea tree oil, sage oil, and clove oil which has been proven effective in 48 hours injection with enclosed feet in shoes and socks.
In the reaffirmed green tea polyphenols (GTP) in inhibited Trichophyton in vitro, researchers at the Tokyo Medical and Dental University launched an evaluation of the effects of GTP on interdigital tinea pedis in a total of 94 infected patients.
The enrolled patients were assigned either to a lukewarm water foot bath containing GTP(0.1% green tea polyphenol solution: 89.5% catechins) or placebo.
The foot baths were given once daily with feet cleaned with mild soap and rinsed with warm water before submerging into the warm GTP foot bath for 15 minutes up to the ankles.
Patients were also given instruction not to dry off the liquids after 15 minutes to ensure further skin penetration of green tea concentration.
At the end of 12 experiments, researchers found that either GTP or placebo exerted a significant reduction in the size of the affected area, the recurrence rate, and the microscopy findings.
In the overall assessment, after taking into account other co and confounders, the green tea treatment group demonstrated significant improvements compared to the placebo group.
These results suggested that green tea (GTP) may process a strong antifungal activity in reduced the symptoms expression of an athlete's foot (tinea pedis), including redness, skin peeling, softening of the tissue.
Therefore, people with long term of athlete's foot (tinea pedis) may be beneficiary by applying the extract in practical use without inducing any adverse effects.
Taken together, green tea polyphenols may be considered as a natural treatment of athlete's foot (tinea pedis), however, due to the small sample size, researchers suggested that large sample size and multi centers investigation are necessary to reaffirm this viability.
Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Effects of a foot bath containing green tea polyphenols on interdigital tinea pedis by Ikeda S1, Kanoya Y, Nagata S.(PubMed)
(2) Athlete’s Foot (tinea pedis) by Centers for Disease Control and Prevention
Sunday, October 6, 2019
Onion's Quercetin inhibits the Effect of Hypertension Against the Risk of Cardiovascular Disease in Overweight and Obese Individuals
Hypertension is a condition of abnormally high blood pressure in the bloodstream. Hypertension a member of the cluster conditions of metabolic syndrome associated with an increased risk of cardiovascular disease and diabetes.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.
Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, inclduing over 650 million were obese worldwide.
Bad eating habits, unhealthy lifestyle and certain medical conditions such as kidney disease, diabetes, and sleep apnea not only induce overweight and obesity but also increase the risk of high blood pressure.
Dr. Shu-Zhong Jiang, the lead scientist wrote, "The imbalance between energy intake and expenditure is the main cause of excessive overweight and obesity. Technically, obesity is defined as the abnormal accumulation of ≥20% of body fat, over the individual's ideal body weight".
And, "Excessive overweight remains among the most neglected public health issues worldwide, while obesity is associated with increased risks of disability, illness, and death. Cardiovascular diseases, the leading cause of mortality worldwide, particularly hypertension and diabetes, are the main illnesses associated with obesity".
The results strongly suggested that obesity not only is associated with hypertension but also is the major contributor to the risk of other chronic diseases.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potential compound for the inhibition of hypertension, researchers examined the effects of polyphenol quercetin in pre-hypertension and stage I hypertension in overweight and obesity individuals.
The double-blinded, placebo-controlled cross-over trial included 70 Subjects randomized to receive 162 mg/d quercetin from onion skin extract powder or placebo for 6-weeks separated by a 6-week washout period.
According to tested assays and compared to the baseline,
* Group treated with quercetin did not significantly show the effect on 24 h ambulatory blood pressure (ABP) parameters and office BP in the hypertensives subgroup.
* However, quercetin decreased 24 h systolic BP by -3·6 mmHg (P=0·022) compared to placebo.
* Furthermore, quercetin treatment significantly decreased day-time and night-time systolic BP in hypertensives without alternating vasoactive biomarkers such as endothelial function, parameters of oxidation, inflammation, lipid, and glucose metabolism in the total and hypertensive subgroup.
Based on the findings, researchers said, " supplementation with 162 mg/d quercetin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quercetin".
In other words, supplementation with 162 mg/d quercetin from onion skin extract protects the heart against CVD by normalizing the blood pressure in hypertensive patients through unknown mechanisms.
Taken altogether, onion may be considered a remedy for the prevention and treatment of liver alcoholic cytotoxicity pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial by Brüll V1, Burak C1, Stoffel-Wagner B2, Wolffram S3, Nickenig G4, Müller C4, Langguth P5, Alteheld B1, Fimmers R6, Naaf S7, Zimmermann BF7, Stehle P1, Egert S. (PubMed)
(2) Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review by Lu M, Cao Y , Xiao J, Song M, and Ho CT. (PubMed)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.
Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, inclduing over 650 million were obese worldwide.
Bad eating habits, unhealthy lifestyle and certain medical conditions such as kidney disease, diabetes, and sleep apnea not only induce overweight and obesity but also increase the risk of high blood pressure.
Dr. Shu-Zhong Jiang, the lead scientist wrote, "The imbalance between energy intake and expenditure is the main cause of excessive overweight and obesity. Technically, obesity is defined as the abnormal accumulation of ≥20% of body fat, over the individual's ideal body weight".
And, "Excessive overweight remains among the most neglected public health issues worldwide, while obesity is associated with increased risks of disability, illness, and death. Cardiovascular diseases, the leading cause of mortality worldwide, particularly hypertension and diabetes, are the main illnesses associated with obesity".
The results strongly suggested that obesity not only is associated with hypertension but also is the major contributor to the risk of other chronic diseases.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potential compound for the inhibition of hypertension, researchers examined the effects of polyphenol quercetin in pre-hypertension and stage I hypertension in overweight and obesity individuals.
The double-blinded, placebo-controlled cross-over trial included 70 Subjects randomized to receive 162 mg/d quercetin from onion skin extract powder or placebo for 6-weeks separated by a 6-week washout period.
According to tested assays and compared to the baseline,
* Group treated with quercetin did not significantly show the effect on 24 h ambulatory blood pressure (ABP) parameters and office BP in the hypertensives subgroup.
* However, quercetin decreased 24 h systolic BP by -3·6 mmHg (P=0·022) compared to placebo.
* Furthermore, quercetin treatment significantly decreased day-time and night-time systolic BP in hypertensives without alternating vasoactive biomarkers such as endothelial function, parameters of oxidation, inflammation, lipid, and glucose metabolism in the total and hypertensive subgroup.
Based on the findings, researchers said, " supplementation with 162 mg/d quercetin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quercetin".
In other words, supplementation with 162 mg/d quercetin from onion skin extract protects the heart against CVD by normalizing the blood pressure in hypertensive patients through unknown mechanisms.
Taken altogether, onion may be considered a remedy for the prevention and treatment of liver alcoholic cytotoxicity pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial by Brüll V1, Burak C1, Stoffel-Wagner B2, Wolffram S3, Nickenig G4, Müller C4, Langguth P5, Alteheld B1, Fimmers R6, Naaf S7, Zimmermann BF7, Stehle P1, Egert S. (PubMed)
(2) Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review by Lu M, Cao Y , Xiao J, Song M, and Ho CT. (PubMed)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)
Green Tea, A Potent with Antioxidant Mouth Rinse
Green tea may have a therapeutic and positive effect in reduced risk of microbial infection, some scientists suggested.
The result of the study was conducted and published online medical literature by some respectable institutes, including the Institute of Dental Sciences.
Green tea, a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the finding of the natural and economic alternative, researchers at the joint study lead by the J. Institute of Dental Sciences conducted an evaluation of the antimicrobial activity of 0.5% green tea and 0.2% CHX mouth rinse against Streptococcus Mutans, Lactobacilli spp. and Candida Albicans.
In the total of 30 children aged 4-6 years with S-ECC (based on defs score) selected and randomly assigned to 2 equal groups rinsed with the prescribed mouth rinse and 0.5% green tea once daily for 2 weeks after breakfast under supervision, researchers found that both applications exerted a statistically significant fall in colony count in Streptococcus Mutans and lactobacilli.
However, Both injection did not express any clinical significant in reduced the colonization of Candida Albicans.
Interestingly, green tea mouth rinse was found to be significantly better than CHX in all aspects except. microbial lactobacilli spp,
In compared anti microbial efficacy of antimicrobial green tea, garlic with lime, and 0.05% sodium fluoride (NaF) mouth rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in a total 45 children aged 4 to 6 years with severe early childhood caries (S-ECC; based on decayed extracted filled [defs] score) selected and divided randomly into three equal groups of to rinse with the prescribed mouth rinse once daily for 2 weeks after breakfast under supervision as mentioned above, researchers indicated that all 3 applications demonstrated a statistically significant reduction of colony count of S. mutans and Lactobacilli spp. but not against C. albicans with no statistically significant differences in three groups compared to baselines and assays.
Dr. Thomas A, the lead author, after taking into account of other confounders, said, "The findings... indicate that green tea and garlic with lime mouth rinse can be an economical alternative to NaF mouth rinse both for prevention and therapeutics".
The above differentiation was supported by the joint study lead by the Institute of Dental Sciences.
According to the result in compared the antimicrobial efficacy of chlorhexidine (0.2%), sodium fluoride (0.05%), fluoride with essential oils (0.05%), alum (0.02 M), green tea, and garlic with lime mouth rinses against Streptococcus mutans, lactobacilli, and Candida albicans through saliva samples collected from children with severe early childhood caries, application of chlorhexidine mouth rinse was most effective against S. mutans and lactobacilli in compared to sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses.
Furthermore, the group treated with a lime mouth rinse exerted a stronger anti-C. albicans activity in compared to chlorhexidine, sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.
Moreover, analysis of the efficacy in the reduced colony of S. mutans and lactobacilli, researchers found that after chlorhexidine mouth rinse, garlic with lime mouth rinse was found to be significantly more effective than sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.
These results indicated that application of green tea with different concentration may have a profound and positive effect in reduced risk of bacterial infection through anti-inflammatory activity of green tea phytochemical polyphenols in protecting our body against infection caused by microbial invasion through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innated anti-inflammatory cytokines.
And antioxidant activities through its bioactive chemical compounds and stimulated production of natural antioxidants found on the host body tissues in the induction of the ROS cytotoxicity against microorganisms without inducing harm to nearby healthy cells.
The results also firmly suggested that green tea mouth rinse can be considered safe, economical and used without much concern.
To view 91 Medical Benefits of Green tea Click Here
Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/
For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-microbial efficacy of green tea and chlorhexidine mouth rinses against Streptococcus mutans, Lactobacilli spp. and Candida albicans in children with severe early childhood caries: A randomized clinical study by Thomas A, Thakur SR1, Shetty SB.(PubMed)
(2) Comparison of Antimicrobial Efficacy of Green Tea, Garlic with Lime, and Sodium Fluoride Mouth Rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in Children: A Randomized Double-blind Controlled Clinical Trial by Thomas A1, Thakur S2, Habib R3.(PubMed)
(3) Comparison of the antimicrobial efficacy of chlorhexidine, sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses on cariogenic microbes by Thomas A1, Thakur S1, Mhambrey S1.(PMC)
(4) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)
The result of the study was conducted and published online medical literature by some respectable institutes, including the Institute of Dental Sciences.
Green tea, a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the finding of the natural and economic alternative, researchers at the joint study lead by the J. Institute of Dental Sciences conducted an evaluation of the antimicrobial activity of 0.5% green tea and 0.2% CHX mouth rinse against Streptococcus Mutans, Lactobacilli spp. and Candida Albicans.
In the total of 30 children aged 4-6 years with S-ECC (based on defs score) selected and randomly assigned to 2 equal groups rinsed with the prescribed mouth rinse and 0.5% green tea once daily for 2 weeks after breakfast under supervision, researchers found that both applications exerted a statistically significant fall in colony count in Streptococcus Mutans and lactobacilli.
However, Both injection did not express any clinical significant in reduced the colonization of Candida Albicans.
Interestingly, green tea mouth rinse was found to be significantly better than CHX in all aspects except. microbial lactobacilli spp,
In compared anti microbial efficacy of antimicrobial green tea, garlic with lime, and 0.05% sodium fluoride (NaF) mouth rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in a total 45 children aged 4 to 6 years with severe early childhood caries (S-ECC; based on decayed extracted filled [defs] score) selected and divided randomly into three equal groups of to rinse with the prescribed mouth rinse once daily for 2 weeks after breakfast under supervision as mentioned above, researchers indicated that all 3 applications demonstrated a statistically significant reduction of colony count of S. mutans and Lactobacilli spp. but not against C. albicans with no statistically significant differences in three groups compared to baselines and assays.
Dr. Thomas A, the lead author, after taking into account of other confounders, said, "The findings... indicate that green tea and garlic with lime mouth rinse can be an economical alternative to NaF mouth rinse both for prevention and therapeutics".
The above differentiation was supported by the joint study lead by the Institute of Dental Sciences.
According to the result in compared the antimicrobial efficacy of chlorhexidine (0.2%), sodium fluoride (0.05%), fluoride with essential oils (0.05%), alum (0.02 M), green tea, and garlic with lime mouth rinses against Streptococcus mutans, lactobacilli, and Candida albicans through saliva samples collected from children with severe early childhood caries, application of chlorhexidine mouth rinse was most effective against S. mutans and lactobacilli in compared to sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses.
Furthermore, the group treated with a lime mouth rinse exerted a stronger anti-C. albicans activity in compared to chlorhexidine, sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.
Moreover, analysis of the efficacy in the reduced colony of S. mutans and lactobacilli, researchers found that after chlorhexidine mouth rinse, garlic with lime mouth rinse was found to be significantly more effective than sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.
These results indicated that application of green tea with different concentration may have a profound and positive effect in reduced risk of bacterial infection through anti-inflammatory activity of green tea phytochemical polyphenols in protecting our body against infection caused by microbial invasion through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innated anti-inflammatory cytokines.
And antioxidant activities through its bioactive chemical compounds and stimulated production of natural antioxidants found on the host body tissues in the induction of the ROS cytotoxicity against microorganisms without inducing harm to nearby healthy cells.
The results also firmly suggested that green tea mouth rinse can be considered safe, economical and used without much concern.
To view 91 Medical Benefits of Green tea Click Here
Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/
For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-microbial efficacy of green tea and chlorhexidine mouth rinses against Streptococcus mutans, Lactobacilli spp. and Candida albicans in children with severe early childhood caries: A randomized clinical study by Thomas A, Thakur SR1, Shetty SB.(PubMed)
(2) Comparison of Antimicrobial Efficacy of Green Tea, Garlic with Lime, and Sodium Fluoride Mouth Rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in Children: A Randomized Double-blind Controlled Clinical Trial by Thomas A1, Thakur S2, Habib R3.(PubMed)
(3) Comparison of the antimicrobial efficacy of chlorhexidine, sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses on cariogenic microbes by Thomas A1, Thakur S1, Mhambrey S1.(PMC)
(4) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)
Saturday, October 5, 2019
Betaxanthins, the Natural Free Radical Scavenger
Free radical scavengers are types of antioxidants that inhibit free radicals before they can induce oxidation.
Antioxidants are stable atoms that inhibit oxidation caused by free radicals.
Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Over time, oxidative stress epidemiologically can cause proteins, lipid, and cellular damage, major causes of heart disease, stroke, and diabetes.
Antioxidants besides produced by the body, they can also come into the body from the dietary sources.
Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.
Dr. Anu Rahal and colleagues in the examination of the interplay of oxidative stress, prooxidants, and antioxidants wrote, "Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis".
And, "the importance of oxidative stress in the body growth and development as well as proteomic and genomic evidences of its relationship with disease development, incidence of malignancies and autoimmune disorders, increased susceptibility to bacterial, viral, and parasitic diseases, and an interplay with prooxidants and antioxidants for maintaining a sound health, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue".
Most common types of free radical scavengers produced by the human
* Catalases are antioxidants that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen.
*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.
*Superoxide dismutase (SOD) dissolves superoxide radical into either ordinary molecular oxygen or hydrogen peroxide.
Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
On finding a potent ingredient for the treatment of diseases associated with oxidative stress, researchers investigated the effects of proline-betaxanthin generated by betalamic acid, the chromophore of betaxanthins.
According to the results of 24 betaxanthin species synthesized by the condensation reaction of purified betalamic acid and amino acids or amines, researchers found that all compounds exerted a significant inhibition of free radicals.
γ-aminobutyric acid (GABA)-betaxanthins, compared to Proline-, dopamine-, under large-scale conditions, and their 1,1-diphenyl-2-picrylhydrazyl showed comparatively low activity,
Furthermore, the free radical scavenging activity of dopamine-betaxanthin was similar to that of red pigment betanin and the anthocyanin cyanidin 3-glucoside.
Moreover, proline-betaxanthin demonstrated the highest antioxidant activity compared to those of dopamine-, 1,1-diphenyl-2-picrylhydrazyl, similar to those of flavonoid quercetin.
Taken altogether, betaxanthins may be considered a free radical scavenging antioxidant remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In vitro synthesis of betaxanthins using recombinant DOPA 4,5-dioxygenase and evaluation of their radical-scavenging activities by Sekiguchi H1, Ozeki Y, Sasaki N. (PubMed)
(2) Oxidative Stress, Prooxidants, and Antioxidants: The Interplay by Anu Rahal, Amit Kumar, Vivek Singh, and Brijesh Yadav. (Research Gate)
Antioxidants are stable atoms that inhibit oxidation caused by free radicals.
Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Over time, oxidative stress epidemiologically can cause proteins, lipid, and cellular damage, major causes of heart disease, stroke, and diabetes.
Antioxidants besides produced by the body, they can also come into the body from the dietary sources.
Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.
Dr. Anu Rahal and colleagues in the examination of the interplay of oxidative stress, prooxidants, and antioxidants wrote, "Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis".
And, "the importance of oxidative stress in the body growth and development as well as proteomic and genomic evidences of its relationship with disease development, incidence of malignancies and autoimmune disorders, increased susceptibility to bacterial, viral, and parasitic diseases, and an interplay with prooxidants and antioxidants for maintaining a sound health, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue".
Most common types of free radical scavengers produced by the human
* Catalases are antioxidants that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen.
*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.
*Superoxide dismutase (SOD) dissolves superoxide radical into either ordinary molecular oxygen or hydrogen peroxide.
Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.
On finding a potent ingredient for the treatment of diseases associated with oxidative stress, researchers investigated the effects of proline-betaxanthin generated by betalamic acid, the chromophore of betaxanthins.
According to the results of 24 betaxanthin species synthesized by the condensation reaction of purified betalamic acid and amino acids or amines, researchers found that all compounds exerted a significant inhibition of free radicals.
γ-aminobutyric acid (GABA)-betaxanthins, compared to Proline-, dopamine-, under large-scale conditions, and their 1,1-diphenyl-2-picrylhydrazyl showed comparatively low activity,
Furthermore, the free radical scavenging activity of dopamine-betaxanthin was similar to that of red pigment betanin and the anthocyanin cyanidin 3-glucoside.
Moreover, proline-betaxanthin demonstrated the highest antioxidant activity compared to those of dopamine-, 1,1-diphenyl-2-picrylhydrazyl, similar to those of flavonoid quercetin.
Taken altogether, betaxanthins may be considered a free radical scavenging antioxidant remedy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In vitro synthesis of betaxanthins using recombinant DOPA 4,5-dioxygenase and evaluation of their radical-scavenging activities by Sekiguchi H1, Ozeki Y, Sasaki N. (PubMed)
(2) Oxidative Stress, Prooxidants, and Antioxidants: The Interplay by Anu Rahal, Amit Kumar, Vivek Singh, and Brijesh Yadav. (Research Gate)
Green Tea Significantly Improved Glucose Metabolism in Prediabetics
Green tea may have a therapeutic and positive effect on improved glucose metabolism, some scientists suggested.
Glucose metabolism is an action of the body to convert glucose intake to energy to nourish the body tissues and organs through oxidized to carbon dioxide and water.
Long term abnormal glucose metabolism is considered as a leading cause of diabetes and diabetic complications.
Green tea extract, in the evaluation of the on carbohydrate metabolic key enzymes in control and streptozotocin high fat diet-induced diabetic rats in 30 days, demonstrated significant activity in ameliorated the overexpression of plasma glucose, glycosylated hemoglobin (HbA1c) and increase in the levels of insulin and hemoglobin.
Further analysis also found that the application exerted a profound effect in restore, in some extends, the function of altered activities of the key enzymes of carbohydrate metabolism, such as hexokinase, pyruvate kinase, lactate dehydrogenase in both diabetic and control groups.
In the diabetic rat's group, green tea extract strongly averted the abnormal expression of glycogen phosphorylase in the liver to near-normal levels.
Additionally, the diabetic group after administration of green tea extract exhibited antihyperglycemic potential, observed through improved muscle and hepatic glycogen content.
The information findings showed green tea extract have a directed implication in attenuated abnormal glucose metabolism in compared to the effectiveness of conventional medicine metformin, a standard oral hypoglycemic drug.
Moreover, in the study to confirm the epidemiological study suggestion of improvement in glucose metabolism in diabetic mice and healthy humans upon green tea consumption, researchers found that
injection green tea in diabetic mice and streptozotocin-induced diabetic mice after 2-6 h expresses lower levels of glucose with no alternation of serum insulin level, at a dose of 300 mg/kg in compared to normal control mice.
In protein differentiation, green tea extract administration decreased the serum protein level which has been associated with glucose production, minimized the increase of blood glucose levels through stimulating additional small amounts of insulin in diabetes. These results addressed another indication of green tea function in exerted direct influence in the modulation of glucose metabolism in the tested subject.
Interestingly, in the investigation of green tea effect in glucose uptake inhibitory activity in Caco-2 cells, researchers indicated that green tea at a temperature of 60 degrees in Celsius significantly improved the capacity of antioxidants in inhibition of glucose uptake through regulation of cellular glucose metabolism.
Incredibly, temperature over 60 degrees Celsius, green tea application did not increase or showed an upward trend in the inhibitory potential, the Huazhong Agricultural University suggested.
Taken together, green tea with abundant bioactive phytochemicals may be considered as a functional food in improved glucose metabolism in reduced risk of diabetes onset. People in high-risk diabetes such as prediabetics may want to add 1 or 2 cups of green tea into their diet for preventive measures.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulatory effect of green tea extract on hepatic key enzymes of glucose metabolism in streptozotocin and high fat diet induced diabetic rats by Sundaram R1, Naresh R, Shanthi P, Sachdanandam P.(PubMed)
(2) Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans by Tsuneki H1, Ishizuka M, Terasawa M, Wu JB, Sasaoka T, Kimura I.(PubMed)
(3) Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake by Liu S1, Ai Z2, Qu F3, Chen Y4, Ni D5.(PubMed)
Glucose metabolism is an action of the body to convert glucose intake to energy to nourish the body tissues and organs through oxidized to carbon dioxide and water.
Long term abnormal glucose metabolism is considered as a leading cause of diabetes and diabetic complications.
Green tea extract, in the evaluation of the on carbohydrate metabolic key enzymes in control and streptozotocin high fat diet-induced diabetic rats in 30 days, demonstrated significant activity in ameliorated the overexpression of plasma glucose, glycosylated hemoglobin (HbA1c) and increase in the levels of insulin and hemoglobin.
Further analysis also found that the application exerted a profound effect in restore, in some extends, the function of altered activities of the key enzymes of carbohydrate metabolism, such as hexokinase, pyruvate kinase, lactate dehydrogenase in both diabetic and control groups.
In the diabetic rat's group, green tea extract strongly averted the abnormal expression of glycogen phosphorylase in the liver to near-normal levels.
Additionally, the diabetic group after administration of green tea extract exhibited antihyperglycemic potential, observed through improved muscle and hepatic glycogen content.
The information findings showed green tea extract have a directed implication in attenuated abnormal glucose metabolism in compared to the effectiveness of conventional medicine metformin, a standard oral hypoglycemic drug.
Moreover, in the study to confirm the epidemiological study suggestion of improvement in glucose metabolism in diabetic mice and healthy humans upon green tea consumption, researchers found that
injection green tea in diabetic mice and streptozotocin-induced diabetic mice after 2-6 h expresses lower levels of glucose with no alternation of serum insulin level, at a dose of 300 mg/kg in compared to normal control mice.
In protein differentiation, green tea extract administration decreased the serum protein level which has been associated with glucose production, minimized the increase of blood glucose levels through stimulating additional small amounts of insulin in diabetes. These results addressed another indication of green tea function in exerted direct influence in the modulation of glucose metabolism in the tested subject.
Interestingly, in the investigation of green tea effect in glucose uptake inhibitory activity in Caco-2 cells, researchers indicated that green tea at a temperature of 60 degrees in Celsius significantly improved the capacity of antioxidants in inhibition of glucose uptake through regulation of cellular glucose metabolism.
Incredibly, temperature over 60 degrees Celsius, green tea application did not increase or showed an upward trend in the inhibitory potential, the Huazhong Agricultural University suggested.
Taken together, green tea with abundant bioactive phytochemicals may be considered as a functional food in improved glucose metabolism in reduced risk of diabetes onset. People in high-risk diabetes such as prediabetics may want to add 1 or 2 cups of green tea into their diet for preventive measures.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modulatory effect of green tea extract on hepatic key enzymes of glucose metabolism in streptozotocin and high fat diet induced diabetic rats by Sundaram R1, Naresh R, Shanthi P, Sachdanandam P.(PubMed)
(2) Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans by Tsuneki H1, Ishizuka M, Terasawa M, Wu JB, Sasaoka T, Kimura I.(PubMed)
(3) Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake by Liu S1, Ai Z2, Qu F3, Chen Y4, Ni D5.(PubMed)
Friday, October 4, 2019
Collard Green Protects the Nerves Against the Risk of Peripheral Neuropathy in Diabetes
Diabetic neuropathy is a complication of patients with diabetes associated with nerve damage, inducing pain and numbness in the legs and feet to conditions associated with the digestive system.
Most cases of diabetic neuropathy in diabetics are involved in a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart due to poor lifestyle.
Peripheral neuropathy is the main type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms. Other main types of diabetic neuropathy are
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks or legs.
* Mononeuropathy, or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso) or leg.
The most common signs and symptoms of peripheral neuropathy are a gradual onset of numbness, prickling or tingling in the feet or hands, over time which can spread upward into your legs and arms.
Some patients with peripheral neuropathy may also experience sharp, jabbing, throbbing or burning pain and skin that extreme sensitivity to touch.
The causes of peripheral neuropathy that damage nerves and blood vessels in the affected area has been found to induce by overtime, uncontrolled high blood sugar.
In other words, peripheral neuropathy is preventable by keeping the blood glucose in the healthy range.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
With an aim to find a potential compound for the prevention of diabetes complications-induced loss of limbs' sensation that results in lower limb amputation in patients with diabetes, researchers examined the effects of sulforaphane on peripheral neuropathy in an animal model.
The experiment included diabetes rats induced through single intraperitoneal injections of nicotinamide (50 mg/kg) and streptozotocin (52.5 mg/kg) randomly divided into five groups
* Two groups were treated with saline or sulforaphane
* Three diabetic groups were either untreated or given sulforaphane (1 mg/kg, p.o.) or pregabalin (10 mg/kg, i.p.).
According to the results of tested analysis after 2 weeks, groups treated with sulforaphane restored animals' body weight, reduced levels of blood glucose in the nicotinamide (50 mg/kg) and streptozotocin (52.5 mg/kg) treated group
Furthermore, glycated hemoglobin and increased insulin levels were also normalized by the administration of sulforaphane, compared to the untreated diabetes groups,
Histopathological changes induced by the nicotinamide (50 mg/kg) and streptozotocin were also reversed in the sulforaphane-treated group observed by the normalizing motor coordination and the latency withdrawal time and increasing the latency withdrawal time.
Furthermore, sulforaphane also decreased markers (malondialdehyde) of oxidative stress of sciatic nerve and inhibited the overexpression of free radicals in the initiation of the production of proinflammatory cytokines and cellular damage compared to untreated groups.
Moreover, levels of antioxidant enzymes in the sciatic nerves produced the treatment groups also significant increase by the injection of sulforaphane.
The results strongly suggested that sulforaphane processed a neuroprotective effect against peripheral neuropathy in diabetic rats possibly through modulating oxidative stress, inflammation, and extracellular matrix associated with cellular differentiation remodeling,
Collectively, researchers wrote in the final report, " In NA-STZ model of diabetes mellitus, sulforaphane, restored animals' body weight, reduced blood glucose, glycated hemoglobin, and increased insulin levels. In parallel, it normalized motor coordination and the latency withdrawal time of the tail-flick test increased the latency withdrawal time of cold allodynia test and ameliorated histopathological changes".
Taken altogether, collard green processed abundantly bioactive compound sulforaphane may be considered supplements for the prevention and treatment of peripheral neuropathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy by Moustafa PE1, Abdelkader NF2, El Awdan SA3, El-Shabrawy OA3, Zaki HF. (PubMed)
Most cases of diabetic neuropathy in diabetics are involved in a history of hyperglycemia caused by long-term high levels of glucose in the bloodstream, urinary tract, blood vessels, and heart due to poor lifestyle.
Peripheral neuropathy is the main type of diabetic neuropathy, affecting the nerves that control the feet and legs first, followed by the hands and arms. Other main types of diabetic neuropathy are
* The autonomic neuropathy that affects the nerves that control the heart, bladder, stomach, intestines, sex organs and eyes.
* Radiculoplexus neuropathy found mostly in older patients affects nerves that control the thighs, hips, buttocks or legs.
* Mononeuropathy, or focal neuropathy also found commonly in older patients affects the nerves that control the face, middle of the body (torso) or leg.
The most common signs and symptoms of peripheral neuropathy are a gradual onset of numbness, prickling or tingling in the feet or hands, over time which can spread upward into your legs and arms.
Some patients with peripheral neuropathy may also experience sharp, jabbing, throbbing or burning pain and skin that extreme sensitivity to touch.
The causes of peripheral neuropathy that damage nerves and blood vessels in the affected area has been found to induce by overtime, uncontrolled high blood sugar.
In other words, peripheral neuropathy is preventable by keeping the blood glucose in the healthy range.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
With an aim to find a potential compound for the prevention of diabetes complications-induced loss of limbs' sensation that results in lower limb amputation in patients with diabetes, researchers examined the effects of sulforaphane on peripheral neuropathy in an animal model.
The experiment included diabetes rats induced through single intraperitoneal injections of nicotinamide (50 mg/kg) and streptozotocin (52.5 mg/kg) randomly divided into five groups
* Two groups were treated with saline or sulforaphane
* Three diabetic groups were either untreated or given sulforaphane (1 mg/kg, p.o.) or pregabalin (10 mg/kg, i.p.).
According to the results of tested analysis after 2 weeks, groups treated with sulforaphane restored animals' body weight, reduced levels of blood glucose in the nicotinamide (50 mg/kg) and streptozotocin (52.5 mg/kg) treated group
Furthermore, glycated hemoglobin and increased insulin levels were also normalized by the administration of sulforaphane, compared to the untreated diabetes groups,
Histopathological changes induced by the nicotinamide (50 mg/kg) and streptozotocin were also reversed in the sulforaphane-treated group observed by the normalizing motor coordination and the latency withdrawal time and increasing the latency withdrawal time.
Furthermore, sulforaphane also decreased markers (malondialdehyde) of oxidative stress of sciatic nerve and inhibited the overexpression of free radicals in the initiation of the production of proinflammatory cytokines and cellular damage compared to untreated groups.
Moreover, levels of antioxidant enzymes in the sciatic nerves produced the treatment groups also significant increase by the injection of sulforaphane.
The results strongly suggested that sulforaphane processed a neuroprotective effect against peripheral neuropathy in diabetic rats possibly through modulating oxidative stress, inflammation, and extracellular matrix associated with cellular differentiation remodeling,
Collectively, researchers wrote in the final report, " In NA-STZ model of diabetes mellitus, sulforaphane, restored animals' body weight, reduced blood glucose, glycated hemoglobin, and increased insulin levels. In parallel, it normalized motor coordination and the latency withdrawal time of the tail-flick test increased the latency withdrawal time of cold allodynia test and ameliorated histopathological changes".
Taken altogether, collard green processed abundantly bioactive compound sulforaphane may be considered supplements for the prevention and treatment of peripheral neuropathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy by Moustafa PE1, Abdelkader NF2, El Awdan SA3, El-Shabrawy OA3, Zaki HF. (PubMed)
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