Tuesday, October 8, 2019

How to Prevent Over Expression of Melanin in Induction of Age Spots Naturally, US National Library of Medicine Studies Reveal

Green tea may have a therapeutic and positive effect in reduced age spots caused by overexpression of melanin, some scientists suggested.

People with a light complexion and lots of sun exposure over the years are found to associate with higher prevalent risk.

The results of this investigation were carried out by some worldwide institutes, including the Chongqing Institute of Forensic Science.


You can view the publication through some online medical literature if you want to know more about these subjects.


An age spot is the overexpression of skin pigment in the surface of the skin, probably caused by Skin aging, sun exposure, or other forms of ultraviolet (UV) light exposure,...

Age spots may also be caused by a hormone imbalance in the induction of increased production of melanin, which is responsible for darkening the skin.

Green tea is a precious drink processed number of health benefits and known to almost everyone in Asia and the Western world.

In the investigation of Epigallocatechin gallate (EGCG), used as a constituent of cosmetic products, researchers found that application EGCG exerts a significant effect as an antioxidant in exhibited anti-pigmentation properties.

Through measuring hyaluronic acid synthase (HAS) and hyaluronidase (HYAL) gene expression, EGCG also promoted skin hydration, through increased the expression of the natural moisturizing factor-related gene, including Hyaluronan synthase (HAS)-1, and (HAS)-2.

HA synthase enzymes (HAS) a molecule with the function of synthesized hyaluronan (HA) plays an essential role in protected skin fibroblasts against apoptosis, due to environmental stress exposure.


Hyaluronidase ((HYAL) is an enzyme that cleaves HA.


In UVB irradiation conditions, the application of EGCG protected the expression of decreased level of HYAL found in all tissues with 50% present in skin, thus reducing HaCaT cell's information of free radicals and decreased in cell viability.

Melanin produced in melanocytes, underexposure UVB irradiation with an aim to protect skin cells against UVB radiation damage.

Years of frequent and prolonged sun exposure and overexpression of melanin may induce aging spot

In other words, EGCG not only exhibited a strong effect in reduced over secretion of melanin but also enhanced cells integrity against forming of the aging spots due to exposure UVB irradiation

HaCaT widely used in scientific research of epidermis is a spontaneously immortalized human keratinocyte cell line isolated from adult human skin.

Dr. Kim E, the lead authors said, "EGCG might be used as a cosmetic ingredient with positive effects on skin hydration, moisture retention, and wrinkle formation, in addition to radical scavenging activity and reduction of melanin generation".

Furthermore, in confirmation of green tea efficacy in reduced overexpression of skin pigment by evaluating the fatty acids contents in the green tea oil, researchers indicated that all 3 major fatty acids isolated from oil were oleic acid (87.93±0.19%), stearic (5.14±0.06%) and palmitic (5.08±0.12%) acids.

A single application of each fatty acid demonstrated strong protection of the cell viabilities through their antioxidant activity.


Moreover, the antioxidant activity of 3% tea seed oil exerted greater cellular protection with cell viability of 90.38±7.77% in compared to other concentrations.

Some researchers suggested that green tea polyphenols and theophylline as polyphenol nanoparticles (PNs) may reduce skin aging through nanoparticle formation process involved copolymerization of monomers through exhibiting its free radicals scavenging activities.

Taking all together, green tea and its bioactive compound such as EGCG may be used as a natural and functional food for reduced overexpression of melanin and skin pigment in the induction of age spots.





Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Skin Protective Effect of Epigallocatechin Gallate by Kim E1, Hwang K2, Lee J3, Han SY4, Kim EM5, Park J6, Cho JY7.(PubMed)
(2) Green Tea Makes Polyphenol Nanoparticles with Radical-Scavenging Activities by Xiang S1, Yang P1, Guo H2, Zhang S1, Zhang X1, Zhu F1, Li Y1.(PubMed)
(3) Melanogenesis Inhibitory and Antioxidant Effects of Camellia oleifera Seed Oil by Chaikul P1,2, Sripisut T1,2, Chanpirom S1,2, Sathirachawan K1, Ditthawuthikul N1,2.(PubMed)

Navy Bean Promotes the Gut Health

The colon formed part of the digestive system is also called the large intestine which plays a critical role in removing water, salt, and forming a stool through its muscles lines.

There are over 100 trillion live in the colon that maintains a healthy balance with the body.

In a normal or healthy individual, gut microbiota besides protecting the host against pathogens that cause infectious disease, it also has strong imparts in some specific function in the host, including
* Nutrient metabolism is a process that absorbs end products of food digestion such as monosaccharides, glucose from carbohydrates, monoacylglycerol and long-chain fatty acids from lipids, and small peptides and amino acids from protein.

* Xenobiotic metabolism is the action that protects the host against chemicals that affect normal metabolism.

* Drug metabolism is the process to alter chemical of a drug that may cause harm to the body

* Gut microbiota also has been found to protect gut mucosal barrier in preserving the ability to absorb nutrients.

* Gut microbiota immunomodulatory activity reduced the risk of disease associated with chronic inflammation of the digestive tract, such as bowel inflammatory disease.

However, there are several factors that may have strong impacts on gut microbiota. Dr. Sai Manasa Jandhyala, the lead scientist wrote, " (1) the mode of delivery (vaginal or cesarean); (2) diet during infancy (breast milk or formula feeds) and adulthood (vegan-based or meat-based); and (3) use of antibiotics or antibiotic like molecules that are derived from the environment of the gut commensal community.

And "A major concern of antibiotic use is the long-term alteration of the normal healthy gut microbiota and horizontal transfer of resistance genes that could result in the reservoir of organisms with a multidrug-resistant gene pool".


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.

On finding a natural compound for the improvement of colon health, researchers examined the effect of cooked navy bean (NB) or black bean (BB) flours on the colonic microenvironment in the gut.

The study included C57Bl/6 mice were fed diets supplemented with 20% cooked navy bean (NB) or black bean (BB) flours or an isocaloric basal diet control (BD) for 3 weeks.


According to the tested analysis* Both NB and BB similarly altered the fecal microbiota community structure by increasing the abundance of carbohydrate fermenting bacteria such as Prevotella, S24-7, and Ruminococcus flavefaciens.
* Both beans also enhanced short-chain fatty acid (SCFA) production (microbial-derived carbohydrate fermentation products) by activating the colonic expression of the SCFA receptors GPR-41/-43/-109a associated with reduced colonic inflammation.

* Furthermore, parameters associated with the improvement of the colon health were also enhanced by the administration of black and navy beans, including the biomarkers of colon barrier integrity such as crypt height, mucus content, cell proliferation, and goblet cell number.

The results strongly suggested that the navy bean improves colon health by increasing the expression of gut "good" microorganisms.

Based on the findings, researchers said, " Overall, NB and BB improved baseline colonic microenvironment function by altering the microbial community structure and activity and promoting colon barrier integrity and function; effects which may prove beneficial in attenuating gut-associated diseases".


Taken altogether, the cooked navy bean may be considered a remedy for the improvement of the colon health, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors by Baxter BA1, Oppel RC2, Ryan EP. (PubMed)
(2) White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate by Monk JM1, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Liu R2, Pauls KP3, Wood GA4, Tsao R2, Robinson LE5, Power KA. (PubMed)
(3) Role of the normal gut microbiota by Sai Manasa Jandhyala, Rupjyoti Talukdar, Chivkula Subramanyam, Harish Vuyyuru, Mitnala Sasikala, and D Nageshwar Reddy. (PMC)

Monday, October 7, 2019

Carotenoids Block the Onset of Colorectal Cancer in Patients with DICER1 rs3742330 Genotypeancer

Cancer is a class of diseases associated with irregular cell growth in the tissue of organs.

The colon-rectum formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.

Colorectal cancer is cancer located in the colon or rectum caused alternation of cell DNA. Most cases of colorectal cancer begin in the cells on the surface of inner ling tissue in either the colon or rectum, before multiplying to form a tumor.

Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.

According to the statistics provided by the American Cancer Society, in the US,
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in 2019.

Additionally, colorectal cancer will also cause the death of 51,020 Americans in 2019.

Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.

Besides adenocarcinomas, the common type of colorectal cancer originated in epithelium tissues and squamous cells that make up the bowel lining together with the gland cells, other types of colorectal tumors include

* Carcinoid
Carcinoid is an unusual type of slow growth neuroendocrine tumor in the hormone-producing tissue in the digestive system. the condition may look benign but can spread to other parts of the body as they grow

* Leiomyosarcomas
Leiomyosarcomas are the rare and resistant types of colorectal cancer and generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.

* Lymphomas
Bowel lymphomas are rare and more likely to start in the rectum rather in the colon. Many patients with lymphomas are diagnosed in the late stage and already spread to other organs.

* Melanomas
Melanomas are a rare malignant tumor of cells that produce the dark pigment. This type of bowel cancer usually originates from somewhere else and then spread to the bowel.

Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.

On finding a potential compound for the treatment of colorectal cancer, researchers investigated whether dietary lutein/zeaxanthin, the major compounds found in carotenoid intake affect colorectal cancer risk in patients with a DICER1 rs3742330 polymorphism.

The experiment included 923 colorectal cancer patients and 1,846 controls based on eligibility criteria, that answered the semiquantitative food frequency questionnaire and the DICER1 rs3742330 genotype.

Based on the returned questionnaire differentiation, the highest quartile of lutein/zeaxanthin consumption was inversely associated with colorectal cancer risk.

In genotype analysis, patients who carry G allele (AG + GG) showed a significantly reduced colorectal cancer incidence compared to that of AA carriers.
Furthermore, patients with G allele (AG + GG) along with high lutein/zeaxanthin consumption were markedly associated with a decreased colorectal cancer risk, particularly in rectal cancer compared to that of AA carriers with low lutein/zeaxanthin intakes.

The results strongly suggested that carotenoids major compounds lutein/zeaxanthin has a strong implication on the colorectal cancer risk in patients with DICER1 rs3742330 genotype.

Dr. Kim J, the lead scientist after taking into account co and confounders wrote in the final report, " colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism".

Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colorectal cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)

Rectal cancer
(1) (1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A > G Polymorphism Relative to Colorectal Cancer Risk by Kim J1, Lee J1, Oh JH2, Chang HJ2, Sohn DK2, Kwon O3, Shin A4, Kim J. (PubMed)
(3) Bowel (Colorectal ) Cancer by Kyle J. Norton

Green Tea, A Potent Ingredient in Inhibited Athlete's Foot (Tinea Pedis)

Green tea may have a therapeutic and positive effect in reduced risk and and treatment of athlete's foot( tinea pedis,), some scientists suggested.

The results of the investigation were reported by several institutes, including the Tokyo Medical and Dental University and published online at medical literature.

Green tea is a precious drink processed a number of health benefits known to almost everyone in Asia and the Western world.

Athlete's foot( tinea pedis) is a common skin disease characterized by a fungal infection.

Uncontrolled proliferation of yeast-fungi not only produces pungent odor but also facilitates the risks of small vesicles, fissures, scaling, and maceration.


Green tea is not one of the favorite natural ingredient used for treatment of athlete's foot (tinea pedis) in compared to the formula of aromatic oil powder-compound consisting of arrowroot, baking soda, basil oil, tea tree oil, sage oil, and clove oil which has been proven effective in 48 hours injection with enclosed feet in shoes and socks.

In the reaffirmed green tea polyphenols (GTP) in inhibited Trichophyton in vitro, researchers at the Tokyo Medical and Dental University launched an evaluation of the effects of GTP on interdigital tinea pedis in a total of 94 infected patients.

The enrolled patients were assigned either to a lukewarm water foot bath containing GTP(0.1% green tea polyphenol solution: 89.5% catechins) or placebo.

The foot baths were given once daily with feet cleaned with mild soap and rinsed with warm water before submerging into the warm GTP foot bath for 15 minutes up to the ankles.

Patients were also given instruction not to dry off the liquids after 15 minutes to ensure further skin penetration of green tea concentration.

At the end of 12 experiments, researchers found that either GTP or placebo exerted a significant reduction in the size of the affected area, the recurrence rate, and the microscopy findings.

In the overall assessment, after taking into account other co and confounders, the green tea treatment group demonstrated significant improvements compared to the placebo group.

These results suggested that green tea (GTP) may process a strong antifungal activity in reduced the symptoms expression of an athlete's foot (tinea pedis), including redness, skin peeling, softening of the tissue.

Therefore, people with long term of athlete's foot (tinea pedis) may be beneficiary by applying the extract in practical use without inducing any adverse effects.

Taken together, green tea polyphenols may be considered as a natural treatment of athlete's foot (tinea pedis), however, due to the small sample size, researchers suggested that large sample size and multi centers investigation are necessary to reaffirm this viability.

Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Effects of a foot bath containing green tea polyphenols on interdigital tinea pedis by Ikeda S1, Kanoya Y, Nagata S.(PubMed)
(2) Athlete’s Foot (tinea pedis) by Centers for Disease Control and Prevention

Sunday, October 6, 2019

Onion's Quercetin inhibits the Effect of Hypertension Against the Risk of Cardiovascular Disease in Overweight and Obese Individuals

Hypertension is a condition of abnormally high blood pressure in the bloodstream. Hypertension a member of the cluster conditions of metabolic syndrome associated with an increased risk of cardiovascular disease and diabetes.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.

Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.



According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.

The formula of the BMI indexBMI= weight (kg)/ height (m2)

According to the statistic, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, inclduing over 650 million were obese worldwide.


Bad eating habits, unhealthy lifestyle and certain medical conditions such as kidney disease, diabetes, and sleep apnea not only induce overweight and obesity but also increase the risk of high blood pressure.

Dr. Shu-Zhong Jiang, the lead scientist wrote, "The imbalance between energy intake and expenditure is the main cause of excessive overweight and obesity. Technically, obesity is defined as the abnormal accumulation of ≥20% of body fat, over the individual's ideal body weight".

And, "Excessive overweight remains among the most neglected public health issues worldwide, while obesity is associated with increased risks of disability, illness, and death. Cardiovascular diseases, the leading cause of mortality worldwide, particularly hypertension and diabetes, are the main illnesses associated with obesity".

The results strongly suggested that obesity not only is associated with hypertension but also is the major contributor to the risk of other chronic diseases.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound for the inhibition of hypertension, researchers examined the effects of polyphenol quercetin in pre-hypertension and stage I hypertension in overweight and obesity individuals.

The double-blinded, placebo-controlled cross-over trial included 70 Subjects randomized to receive 162 mg/d quercetin from onion skin extract powder or placebo for 6-weeks separated by a 6-week washout period.

According to tested assays and compared to the baseline,
* Group treated with quercetin did not significantly show the effect on 24 h ambulatory blood pressure (ABP) parameters and office BP in the hypertensives subgroup.

* However, quercetin decreased 24 h systolic BP by -3·6 mmHg (P=0·022) compared to placebo.

* Furthermore, quercetin treatment significantly decreased day-time and night-time systolic BP in hypertensives without alternating vasoactive biomarkers such as endothelial function, parameters of oxidation, inflammation, lipid, and glucose metabolism in the total and hypertensive subgroup.


Based on the findings, researchers said, " supplementation with 162 mg/d quercetin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quercetin".

In other words, supplementation with 162 mg/d quercetin from onion skin extract protects the heart against CVD by normalizing the blood pressure in hypertensive patients through unknown mechanisms.

Taken altogether, onion may be considered a remedy for the prevention and treatment of liver alcoholic cytotoxicity pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial by Brüll V1, Burak C1, Stoffel-Wagner B2, Wolffram S3, Nickenig G4, Müller C4, Langguth P5, Alteheld B1, Fimmers R6, Naaf S7, Zimmermann BF7, Stehle P1, Egert S. (PubMed)
(2) Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review by Lu M, Cao Y , Xiao J, Song M, and Ho CT. (PubMed)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)

Green Tea, A Potent with Antioxidant Mouth Rinse

Green tea may have a therapeutic and positive effect in reduced risk of microbial infection, some scientists suggested.

The result of the study was conducted and published online medical literature by some respectable institutes, including the Institute of Dental Sciences.


Green tea, a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.


In the finding of the natural and economic alternative, researchers at the joint study lead by the J. Institute of Dental Sciences conducted an evaluation of the antimicrobial activity of 0.5% green tea and 0.2% CHX mouth rinse against Streptococcus Mutans, Lactobacilli spp. and Candida Albicans.

In the total of 30 children aged 4-6 years with S-ECC (based on defs score) selected and randomly assigned to 2 equal groups rinsed with the prescribed mouth rinse and 0.5% green tea once daily for 2 weeks after breakfast under supervision, researchers found that both applications exerted a statistically significant fall in colony count in Streptococcus Mutans and lactobacilli.

However, Both injection did not express any clinical significant in reduced the colonization of Candida Albicans.

Interestingly, green tea mouth rinse was found to be significantly better than CHX in all aspects except. microbial lactobacilli spp,

In compared anti microbial efficacy of antimicrobial green tea, garlic with lime, and 0.05% sodium fluoride (NaF) mouth rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in a total 45 children aged 4 to 6 years with severe early childhood caries (S-ECC; based on decayed extracted filled [defs] score) selected and divided randomly into three equal groups of to rinse with the prescribed mouth rinse once daily for 2 weeks after breakfast under supervision as mentioned above, researchers indicated that all 3 applications demonstrated a statistically significant reduction of colony count of S. mutans and Lactobacilli spp. but not against C. albicans with no statistically significant differences in three groups compared to baselines and assays.

Dr. Thomas A, the lead author, after taking into account of other confounders, said, "The findings... indicate that green tea and garlic with lime mouth rinse can be an economical alternative to NaF mouth rinse both for prevention and therapeutics".

The above differentiation was supported by the joint study lead by the Institute of Dental Sciences.

According to the result in compared the antimicrobial efficacy of chlorhexidine (0.2%), sodium fluoride (0.05%), fluoride with essential oils (0.05%), alum (0.02 M), green tea, and garlic with lime mouth rinses against Streptococcus mutans, lactobacilli, and Candida albicans through saliva samples collected from children with severe early childhood caries, application of chlorhexidine mouth rinse was most effective against S. mutans and lactobacilli in compared to sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses.

Furthermore, the group treated with a lime mouth rinse exerted a stronger anti-C. albicans activity in compared to chlorhexidine, sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.

Moreover, analysis of the efficacy in the reduced colony of S. mutans and lactobacilli, researchers found that after chlorhexidine mouth rinse, garlic with lime mouth rinse was found to be significantly more effective than sodium fluoride, fluoride with essential oils, alum, and green tea mouth rinses.

These results indicated that application of green tea with different concentration may have a profound and positive effect in reduced risk of bacterial infection through anti-inflammatory activity of green tea phytochemical polyphenols in protecting our body against infection caused by microbial invasion through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innated anti-inflammatory cytokines.

And antioxidant activities through its bioactive chemical compounds and stimulated production of natural antioxidants found on the host body tissues in the induction of the ROS cytotoxicity against microorganisms without inducing harm to nearby healthy cells.

The results also firmly suggested that green tea mouth rinse can be considered safe, economical and used without much concern.


To view 91 Medical Benefits of Green tea Click Here




Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/





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Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-microbial efficacy of green tea and chlorhexidine mouth rinses against Streptococcus mutans, Lactobacilli spp. and Candida albicans in children with severe early childhood caries: A randomized clinical study by Thomas A, Thakur SR1, Shetty SB.(PubMed)
(2) Comparison of Antimicrobial Efficacy of Green Tea, Garlic with Lime, and Sodium Fluoride Mouth Rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans in Children: A Randomized Double-blind Controlled Clinical Trial by Thomas A1, Thakur S2, Habib R3.(PubMed)
(3) Comparison of the antimicrobial efficacy of chlorhexidine, sodium fluoride, fluoride with essential oils, alum, green tea, and garlic with lime mouth rinses on cariogenic microbes by Thomas A1, Thakur S1, Mhambrey S1.(PMC)
(4) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)

Saturday, October 5, 2019

Betaxanthins, the Natural Free Radical Scavenger

Free radical scavengers are types of antioxidants that inhibit free radicals before they can induce oxidation.

Antioxidants are stable atoms that inhibit oxidation caused by free radicals.

Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Over time, oxidative stress epidemiologically can cause proteins, lipid, and cellular damage, major causes of heart disease, stroke, and diabetes.

Antioxidants besides produced by the body, they can also come into the body from the dietary sources.

Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.

Dr. Anu Rahal and colleagues in the examination of the interplay of oxidative stress, prooxidants, and antioxidants wrote, "Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis".


And, "the importance of oxidative stress in the body growth and development as well as proteomic and genomic evidences of its relationship with disease development, incidence of malignancies and autoimmune disorders, increased susceptibility to bacterial, viral, and parasitic diseases, and an interplay with prooxidants and antioxidants for maintaining a sound health, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue".


Most common types of free radical scavengers produced by the human
* Catalases are antioxidants that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen.

*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.

*Superoxide dismutase (SOD) dissolves superoxide radical into either ordinary molecular oxygen or hydrogen peroxide.

Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.

On finding a potent ingredient for the treatment of diseases associated with oxidative stress, researchers investigated the effects of proline-betaxanthin generated by betalamic acid, the chromophore of betaxanthins.

According to the results of 24 betaxanthin species synthesized by the condensation reaction of purified betalamic acid and amino acids or amines, researchers found that all compounds exerted a significant inhibition of free radicals.

γ-aminobutyric acid (GABA)-betaxanthins, compared to Proline-, dopamine-, under large-scale conditions, and their 1,1-diphenyl-2-picrylhydrazyl showed comparatively low activity,

Furthermore, the free radical scavenging activity of dopamine-betaxanthin was similar to that of red pigment betanin and the anthocyanin cyanidin 3-glucoside.

Moreover, proline-betaxanthin demonstrated the highest antioxidant activity compared to those of dopamine-, 1,1-diphenyl-2-picrylhydrazyl, similar to those of flavonoid quercetin.

Taken altogether, betaxanthins may be considered a free radical scavenging antioxidant remedy, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) In vitro synthesis of betaxanthins using recombinant DOPA 4,5-dioxygenase and evaluation of their radical-scavenging activities by Sekiguchi H1, Ozeki Y, Sasaki N. (PubMed)
(2) Oxidative Stress, Prooxidants, and Antioxidants: The Interplay by Anu Rahal, Amit Kumar, Vivek Singh, and Brijesh Yadav. (Research Gate)