The bladder formed part of the secretory system is a muscular sac in the pelvis, just above and behind the pubic bone.
The bladder has 2 main functions that store the urine made in the kidneys and control urinary secretion.
Cancer is a group of chronic diseases characterized by cell growth disorderly that starts on the surface of the inner lining tissue of a specific tissue of a gland or organ.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women, Bladder cancer usually starts from the cells on the surface of inner tissue that the lines the bladder.
Bladder cancer depending on the origination of cancer beginning can be classified into
* Transitional cell carcinoma
In the early stage of bladder cancer, normal cells become cancerous in the innermost tissue layer of the bladder which can change shape and stretch without breaking apart. In other words, cancer in this stage is able to stretch when the bladder is full and shrink when the bladder is emptied.
More than 90 percent of bladder cancers begin in the transitional cells
* Squamous cell carcinoma
Cancer begins in squamous cells found in the tissues of the surface of the bladder, due to long-term infection or irritation. About 8 percent of people with bladder cancers begin squamous cells.
* Adenocarcinoma
Cancer originates from the glandular tissue of the bladder, including the surface layer of skin, glands and a variety of other tissue, due to long-term irritation and inflammation. Only 2 percent of people with the condition have a third bladder cancer type.
The exact causes of bladder cancer are unidentified. However, smoking has been associated with a significant factor that causes the onset of the disease.
Dr. Neal D Freedman, the lead scientist wrote, "Previous studies indicate that the population attributable risk of bladder cancer for tobacco smoking is 50–65% in men and 20–30% in women and that current cigarette smoking triples bladder cancer risk relative to never smoking".
And, "Over the last 30 years, incidence rates have remained stable in the United States (men: 123.8/100,000 person-years to 142.2/100,000 person-years; women: 32.5/100,000 person-years to 33.2/100,000 person-years)".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of bladder cancer, researchers examined the anti-proliferative activities of cranberry derived flavonoids on human bladder tumor cell lines (RT4, SCABER, and SW-780) and non-tumorigenic immortalized human uroepithelial cells (SV-HUC).
According to the tested analysis,
* Quercetin 3-O-glucoside, isorhamnetin (3'-O-methyl quercetin), myricetin and quercetin found in cranberry showed strong concentration-dependent cell growth inhibitory activities in bladder cancer cells with IC50 values in a range of 8-92 μM compared to others.
* Isorhamnetin and myricetin had very low inhibitory activity against SV-HUC even at very high concentrations (>200 μM) compared to bladder cancer cells.
These results strongly suggested that isorhamnetin and myricetin inhibited bladder cancer cells without causing harm to the nearby healthy cells.
Furthermore, according to the results of SW-780 cells incubated with the aforementioned compounds, hyperoside, a member of 3-O-galactoside of quercetin undergoes relatively less metabolic biotransformation (methylation, glucuronidation and quinone formation) compared to quercetin 3-O-glucoside.
Based on the findings, researchers said, "isorhamnetin and quercetin 3-O-glucoside may be the active forms of quercetin in the prevention of bladder cancer".
Taken altogether, cranberry processed abundantly bioactive compounds may be considered a remedy for the prevention and treatment of bladder cancer pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells by Prasain JK1, Rajbhandari R1, Keeton AB2, Piazza GA2, Barnes S. (PubMed)
(2) Cranberries and Cancer: An Update of Preclinical Studies Evaluating the CancerInhibitory Potential of Cranberry and Cranberry Derived Constituents by Weh KM1, Clarke J2,3,4, Kresty LA. (PubMed)
(3) Association between smoking and risk of bladder cancer among men and women by Neal D Freedman, PhD, MPH,1 Debra T Silverman, ScD, ScM,1 Albert R Hollenbeck, PhD,2Arthur Schatzkin, MD, DrPH,1 and Christian C Abnet, PhD, MPH. (PMC)
Sunday, October 13, 2019
How to Protect Your Skin Against Histamine Release In Induction of Hives Effectively
Green tea may have a therapeutic and positive effect on reduced risk of the sudden appearance of hives, some scientists suggested.
Hives, also known as Urticaria, is the condition characterized by a sudden outbreak of swollen, pale red bumps or plaques on the skin.
The exact causes of hives are unknown, However, epidemiological studies all agreed that a set of conditions such as allergic reactions, chemicals in foods, insect stings, sunlight exposure, or medications can all cause histamine release initiated the onset of hives.
Certain diseases such as thyroid disease, hepatitis, infection,.... and cancer are also associated with the onset of chronic hives.
Acute conditions of Hives are diseases that last less than six weeks.
Most common symptoms of chronic hives include red, itchy or skin color welts on the skin that appear in varying shapes and sizes and anywhere in the body that last no longer than six to 12 hours.
In severe cases, chronic hives may induce symptoms of dizziness. wheezing. difficulty breathing,........ and swelling of the tongue, lips, or face.
According to statistics, approximately, 20 percent of people may develop hives at some time in their life.
According to the returned of 437 response rate (95%) questionnaires from the fourth to sixth-grade students at an elementary school in Yongin conducted by the J Dankook University to examine the food allergy that affects between 10.9% to 12.6% general population(2).* The prevalence of food allergy among respondents was 19.7%.
* The the most common food allergy-related symptoms were urticaria
These results suggested that food allergens are one of the leading causes of the onset of hives among children between ages 9 - 12.
The study also suggested that green tea inhibits hives onset through its antihistamine effect.
Furthermore, Green tea also processes anti-inflammatory properties that can soothe swelling and reduce skin discomfort.
According to the Universidad de Málaga and CIBER de Enfermedades Raras (CIBERER), green tea bioactive compound epigallocatechin-3-gallate (EGCG), exerted anti-allergen caused by histamine-producing cells through alterations in their behavior such as their proliferative, adhesion, migration, and invasion potentials.
By exhibiting the anti antihistamine effect, green tea may have potency in reduced risk of acute and chronic skin diseases caused by food allergens, including hives(2).
Dr. Melgarejo E, the lead author said, "green tea EGCG has been shown to have potent anti-inflammatory, anti-tumoral, and anti-angiogenic effects and to be a potent inhibitor of the histamine-producing enzyme, histidine decarboxylase"(2).
Taken together, green tea and its bioactive phytochemical EGCG may be considered as a functional food in inhibit hives caused by overexpression of histamine.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton(Scholar, Master of Nutrition, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including world wide health, ezine articles, article base, healthblogs, self growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Diet in dermatology: Part II. Melanoma, chronic urticaria, and psoriasis by Murzaku EC1, Bronsnick T2, Rao BK1(PubMed)
(2) Targeting of histamine producing cells by EGCG: a green dart against inflammation? by Melgarejo E1, Medina MA, Sánchez-Jiménez F, Urdiales JL(PubMed)
(3) Food allergy knowledge, perception of food allergy labeling, and level of dietary practice: A comparison between children with and without food allergy experience by Choi Y1, Ju S2, Chang H2.(PubMed)
Hives, also known as Urticaria, is the condition characterized by a sudden outbreak of swollen, pale red bumps or plaques on the skin.
The exact causes of hives are unknown, However, epidemiological studies all agreed that a set of conditions such as allergic reactions, chemicals in foods, insect stings, sunlight exposure, or medications can all cause histamine release initiated the onset of hives.
Certain diseases such as thyroid disease, hepatitis, infection,.... and cancer are also associated with the onset of chronic hives.
Acute conditions of Hives are diseases that last less than six weeks.
Most common symptoms of chronic hives include red, itchy or skin color welts on the skin that appear in varying shapes and sizes and anywhere in the body that last no longer than six to 12 hours.
In severe cases, chronic hives may induce symptoms of dizziness. wheezing. difficulty breathing,........ and swelling of the tongue, lips, or face.
According to statistics, approximately, 20 percent of people may develop hives at some time in their life.
According to the returned of 437 response rate (95%) questionnaires from the fourth to sixth-grade students at an elementary school in Yongin conducted by the J Dankook University to examine the food allergy that affects between 10.9% to 12.6% general population(2).* The prevalence of food allergy among respondents was 19.7%.
* The the most common food allergy-related symptoms were urticaria
These results suggested that food allergens are one of the leading causes of the onset of hives among children between ages 9 - 12.
The study also suggested that green tea inhibits hives onset through its antihistamine effect.
Furthermore, Green tea also processes anti-inflammatory properties that can soothe swelling and reduce skin discomfort.
According to the Universidad de Málaga and CIBER de Enfermedades Raras (CIBERER), green tea bioactive compound epigallocatechin-3-gallate (EGCG), exerted anti-allergen caused by histamine-producing cells through alterations in their behavior such as their proliferative, adhesion, migration, and invasion potentials.
By exhibiting the anti antihistamine effect, green tea may have potency in reduced risk of acute and chronic skin diseases caused by food allergens, including hives(2).
Dr. Melgarejo E, the lead author said, "green tea EGCG has been shown to have potent anti-inflammatory, anti-tumoral, and anti-angiogenic effects and to be a potent inhibitor of the histamine-producing enzyme, histidine decarboxylase"(2).
Taken together, green tea and its bioactive phytochemical EGCG may be considered as a functional food in inhibit hives caused by overexpression of histamine.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton(Scholar, Master of Nutrition, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including world wide health, ezine articles, article base, healthblogs, self growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Diet in dermatology: Part II. Melanoma, chronic urticaria, and psoriasis by Murzaku EC1, Bronsnick T2, Rao BK1(PubMed)
(2) Targeting of histamine producing cells by EGCG: a green dart against inflammation? by Melgarejo E1, Medina MA, Sánchez-Jiménez F, Urdiales JL(PubMed)
(3) Food allergy knowledge, perception of food allergy labeling, and level of dietary practice: A comparison between children with and without food allergy experience by Choi Y1, Ju S2, Chang H2.(PubMed)
Saturday, October 12, 2019
Healthy Legume Navy Bean Reduces the Risk and Onset of Cardiovascular Disease
Cardiovascular disease (CVD) is a class of diseases involved in the heart or blood vessels. In other words, CVD includes heart disease and stroke
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart diseases are caused by high blood pressure that contributes to hardening of the arteries, and high levels of bad cholesterol (LDL) that causes the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including the 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart diseases, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy bean had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hypercholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken altogether, navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
Heart Disease is a medical condition associated with reduced function of the heart in pumping blood to the body through its blood vessels.
In the US, heart disease causes the death of approximately 610,000 Americans every year. More precisely 1 in every 4 deaths in the US is associated with heart disease.
Most cases of heart diseases are caused by high blood pressure that contributes to hardening of the arteries, and high levels of bad cholesterol (LDL) that causes the build-up of plaque in the arteries.
High levels of bad cholesterol (LDL) have been found epidemiologically, associated with an uncontrolled diet with high levels of saturated fat and trans fat, which lead to the formation of atherosclerosis lesions and eventually arterial blockage.
In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart is a risk of heart disease.
A stroke is caused by the interruption or reduction of blood supply to part of the brain that deprives the brain tissue of oxygen and nutrients, leading to the death of brain cells.
According to the statistics, every year, more than 795,000 people in the US have a stroke, including the 610,000 cases of new strokes.
Believe it or not, 1 of 4 cases of stroke are in people who have had a previous stroke.
There are similar causes of stroke and heart diseases, but in stroke, the result is more severe. Any delay in rescuing will result in the death of the victim.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. The legume is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential ingredient for the prevention and treatment of cardiovascular disease, researchers examined the navy beans and rice bran effect on regulating blood lipids in adults and children.
The pilot, randomized-controlled, clinical trial included 38 children (10 ± 0.8 years old) with abnormal cholesterol who consumed a snack for 4 weeks containing either: no navy bean or rice bran (control); 17.5 g/day cooked navy bean powder; 15 g/day heat-stabilized rice bran; or 9 g/day navy beans and 8 g/day rice bran.
According to the analysis of the plasma metabolites extracted, navy bean and/or rice bran consumption influenced 71 plasma compounds compared to control (p ≤ 0.05), with lipids representing 46% of the total plasma metabolome.
In other words, navy bean intake causes significant changes of 18 plasma lipids compared to only 10 plasma lipids for the rice bran group and 48 lipids compared to only 40 in the rice bran group compared to baseline.
More precisely, the intake of navy bean had a positive impact on blood lipid metabolism in reducing CVD risk in children.
Additional differentiation of the navy bean anti hypercholesterol activity, researchers found that the efficacy of navy bean was attributed to the decrease of free fatty acids associated with metabolic diseases (palmitate and arachidonate) and increase of the relative abundance of endogenous anti-inflammatory lipids.
Based on the results, researchers said, " Findings from this pilot study support the need for investigating the effects of these foods for longer durations to reduce CVD risk".
Taken altogether, navy bean may be considered a remedy for the prevention and treatment of cardiovascular disease caused by high blood cholesterol, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Navy Bean and Rice Bran Intake Alters the Plasma Metabolome of Children at Risk for Cardiovascular Disease by Li KJ1, Borresen EC1, Jenkins-Puccetti N2, Luckasen G2, Ryan EP. (PubMed)
(2) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(3) Stroke -- The Causes by Kyle J. Norton
How to Prevent and Treat Infectious Diseases Naturally and Effectively, MEDLINE Studies Suggestions
Including green tea as a beverage in your diet may have a therapeutic and positive effect in reduced risk and treatment of bacterial and viral infectious diseases, some scientists suggested.
The results of the analysis were carried out by numbers of institutes, including the Yonsei University and punished on online medical literature.
Green tea is a precious drink processed a number of health benefits known to almost everyone in Asia and the Western world.
According to Review provided by VeriMed Healthcare Network. intake of green tea 2 to 4 cups per day by steep covered 5 to 10 minutes for leaf or flowers and 10 to 20 minutes for roots was associated with the support immunity while providing antibacterial and antiviral activity.
Also, green tea (Camellia sinensis) extract of 250 to 500 mg daily, enhanced immune function due to its antioxidant, anti-inflammatory, and immune effects.
Moreover, tannin, green tea derived polyphenols and other related compounds, in the study to investigate the anti-viral effects of tannins on 12 different viruses including both enveloped viruses (influenza virus H3N2, H5N3, herpes simplex virus-1, vesicular stomatitis virus, Sendai virus and Newcastle disease virus) and non-enveloped viruses (poliovirus, coxsachievirus, adenovirus, rotavirus, feline calicivirus and mouse norovirus) researchers suggested that application of tannin reduced some viral infectivity in compared to persimmon (Diospyros kaki) with more than 4-log scale against all of the viruses tested.
More importantly, the differentiation of epigallocatechin-3-gallate (EGCG) effect against viral infections also indicated that EGCG injection in solution type and powder types over extended periods at various temperature conditions exerts a strong effect in inhibited the tested human influenza A/H1N1 virus.
Green tea extract in the study also demonstrated potent viral inactivating activity for over a period of up to 2 months.
These results suggested that adding green tea supplement GTE may provide a greater than 4 log10 reduction of viral titers at a wide range of temperatures.
Dr. Lee YH, after taking into account of other co and confouders said, "GTE-based antiviral agents could be formulated as a safe and environmentally friendly personal hygiene against viral infections".
The findings showed that green tea and green tea extract may be considered as functional foods in reduced risk and treatment of infectious diseases caused by the bacterial and viral invasion.
However, the intake of green tea supplementations should be taken with extreme care as acute liver toxicity has been reported in numbers of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Measle Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
(2) Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses
Kyoko Ueda, 1 Ryoko Kawabata, 1 Takashi Irie, 1 Yoshiaki Nakai, 2 Yukinobu Tohya, 3 and Takemasa Sakaguchi 1 (PMC)
(2) Evaluation of green tea extract as a safe personal hygiene against viral infections by Lee YH#1, Jang YH#1, Kim YS1, Kim J2,3, Seong BL1,4.(PubMed)
The results of the analysis were carried out by numbers of institutes, including the Yonsei University and punished on online medical literature.
Green tea is a precious drink processed a number of health benefits known to almost everyone in Asia and the Western world.
According to Review provided by VeriMed Healthcare Network. intake of green tea 2 to 4 cups per day by steep covered 5 to 10 minutes for leaf or flowers and 10 to 20 minutes for roots was associated with the support immunity while providing antibacterial and antiviral activity.
Also, green tea (Camellia sinensis) extract of 250 to 500 mg daily, enhanced immune function due to its antioxidant, anti-inflammatory, and immune effects.
Moreover, tannin, green tea derived polyphenols and other related compounds, in the study to investigate the anti-viral effects of tannins on 12 different viruses including both enveloped viruses (influenza virus H3N2, H5N3, herpes simplex virus-1, vesicular stomatitis virus, Sendai virus and Newcastle disease virus) and non-enveloped viruses (poliovirus, coxsachievirus, adenovirus, rotavirus, feline calicivirus and mouse norovirus) researchers suggested that application of tannin reduced some viral infectivity in compared to persimmon (Diospyros kaki) with more than 4-log scale against all of the viruses tested.
More importantly, the differentiation of epigallocatechin-3-gallate (EGCG) effect against viral infections also indicated that EGCG injection in solution type and powder types over extended periods at various temperature conditions exerts a strong effect in inhibited the tested human influenza A/H1N1 virus.
Green tea extract in the study also demonstrated potent viral inactivating activity for over a period of up to 2 months.
These results suggested that adding green tea supplement GTE may provide a greater than 4 log10 reduction of viral titers at a wide range of temperatures.
Dr. Lee YH, after taking into account of other co and confouders said, "GTE-based antiviral agents could be formulated as a safe and environmentally friendly personal hygiene against viral infections".
The findings showed that green tea and green tea extract may be considered as functional foods in reduced risk and treatment of infectious diseases caused by the bacterial and viral invasion.
However, the intake of green tea supplementations should be taken with extreme care as acute liver toxicity has been reported in numbers of cases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Measle Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
(2) Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses
Kyoko Ueda, 1 Ryoko Kawabata, 1 Takashi Irie, 1 Yoshiaki Nakai, 2 Yukinobu Tohya, 3 and Takemasa Sakaguchi 1 (PMC)
(2) Evaluation of green tea extract as a safe personal hygiene against viral infections by Lee YH#1, Jang YH#1, Kim YS1, Kim J2,3, Seong BL1,4.(PubMed)
Friday, October 11, 2019
Herbal Ashwagandha, the Potential Anti Colon Cancer Functional Remedy
Cancer is a group of chronic diseases caused by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
Colon cancer is a chronic condition characterized by uncontrolled cell growth in the colon tissue.
Most cases of colon cancer start with the alternation of cells DNA in the cells on the surface of the inner lining colon tissue before proliferating into deeper tissues to form a tumor through abnormal cell cycle division.
The colon formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colon cancer is relatively very common, slowly growing and progressing cancer.
According to the statistics provided by the American Cancer Society, in 2019, colorectal cancer including colon and rectal cancer is the third most common cancer diagnosed in both men and women in the United States.
In 2019, 101,420 people in the US will be diagnosed with colon cancer.
Most common symptoms of colon cancer are a persistent change in your bowel habits, including diarrhea or constipation, blood in your stool, persistent abdominal discomforts, such feeling that your bowel doesn't empty completely accompanied by some general symptoms shared by other types of cancer.
The exact causes of colon cancer are unknown. However, out of many risk factors associated with the onset of the disease, aging may have a strong implication involved in cancer, as most cases of the colon are found in the older population.
Dr. O Ng and colleagues in a joint study led by the University of Nottingham wrote, "The prevalence of colorectal cancer is increasing in the elderly. We examined the treatment and outcomes in our institution of patients aged over 85 years with proven colorectal adenocarcinoma".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potential compound for the treatment of colon cancer with no side effect, researchers examined the effects of Withaferin-A, a withanolide derived from the leaf extract of W. somnifera, anti-colon tumor activity.
On human colorectal cancer (HCT116) cells, the phytochemical not only inhibited the proliferation but also the migration of the tested cancer cells in a concentration-dependent manner.
In other words, Withaferin-A exhibited cell cycle arrest and blocking cancer cell spreading.
Furthermore, the administration of withaferin-A attenuated the expression of pro-inflammatory cytokines activated by protein (STAT3) associated with the development and progression of colon cancer.
On HCT116 cells xenograft tumors and generated in Balb/c nude mice, withaferin-A showed a strong activity in which a significant decrease in the volume and weight of tumors, compared to untreated controls.
Based on the finding, researchers said, "The present study suggests that withaferin-A holds the potential to be developed as a small molecule inhibitor of STAT3 for the treatment of HCT116".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of colon cancer in vitro and vivo.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)
(2) Immunomodulatory effects of Withania somnifera on azoxymethane-induced experimental colon cancer in mice by Muralikrishnan G1, Dinda AK, Shakeel F. (PubMed)
(3) Colorectal cancer outcomes in patients aged over 85 years by O Ng,1 E Watts,2 CA Bull,2 R Morris,3 A Acheson,2 and A Banerjea. (PMC)
Colon cancer is a chronic condition characterized by uncontrolled cell growth in the colon tissue.
Most cases of colon cancer start with the alternation of cells DNA in the cells on the surface of the inner lining colon tissue before proliferating into deeper tissues to form a tumor through abnormal cell cycle division.
The colon formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colon cancer is relatively very common, slowly growing and progressing cancer.
According to the statistics provided by the American Cancer Society, in 2019, colorectal cancer including colon and rectal cancer is the third most common cancer diagnosed in both men and women in the United States.
In 2019, 101,420 people in the US will be diagnosed with colon cancer.
Most common symptoms of colon cancer are a persistent change in your bowel habits, including diarrhea or constipation, blood in your stool, persistent abdominal discomforts, such feeling that your bowel doesn't empty completely accompanied by some general symptoms shared by other types of cancer.
The exact causes of colon cancer are unknown. However, out of many risk factors associated with the onset of the disease, aging may have a strong implication involved in cancer, as most cases of the colon are found in the older population.
Dr. O Ng and colleagues in a joint study led by the University of Nottingham wrote, "The prevalence of colorectal cancer is increasing in the elderly. We examined the treatment and outcomes in our institution of patients aged over 85 years with proven colorectal adenocarcinoma".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potential compound for the treatment of colon cancer with no side effect, researchers examined the effects of Withaferin-A, a withanolide derived from the leaf extract of W. somnifera, anti-colon tumor activity.
On human colorectal cancer (HCT116) cells, the phytochemical not only inhibited the proliferation but also the migration of the tested cancer cells in a concentration-dependent manner.
In other words, Withaferin-A exhibited cell cycle arrest and blocking cancer cell spreading.
Furthermore, the administration of withaferin-A attenuated the expression of pro-inflammatory cytokines activated by protein (STAT3) associated with the development and progression of colon cancer.
On HCT116 cells xenograft tumors and generated in Balb/c nude mice, withaferin-A showed a strong activity in which a significant decrease in the volume and weight of tumors, compared to untreated controls.
Based on the finding, researchers said, "The present study suggests that withaferin-A holds the potential to be developed as a small molecule inhibitor of STAT3 for the treatment of HCT116".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of colon cancer in vitro and vivo.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)
(2) Immunomodulatory effects of Withania somnifera on azoxymethane-induced experimental colon cancer in mice by Muralikrishnan G1, Dinda AK, Shakeel F. (PubMed)
(3) Colorectal cancer outcomes in patients aged over 85 years by O Ng,1 E Watts,2 CA Bull,2 R Morris,3 A Acheson,2 and A Banerjea. (PMC)
Green Tea and Its Bioactive Polyphenol EGCG Kill Bacteria That Cause Carbuncle
Green tea may have a therapeutic and positive effect in reduced risk and progression and treatment of carbuncle, a skin disease, some scientists suggested.
Carbuncle is a collection of boils developed under the skin caused by bacterial infection of hair follicles in the induction of swelling.
Although the infections are most likely developing on the follicles of the hair, they can also appear on other areas of the body such as the buttocks, thighs, groin, and armpits.
Researchers suggested that people who are older age, obesity, poor hygiene, and poor health are most likely associated with increased risk of carbuncles.
However, chronic skin conditions, chronic kidney disease,.... and liver disease are also increased the prevalent risk of the infection.
According to University of Miami School of Medicine, "Skin infections account for a significant portion of dermatologic disease, often resulting in or as a consequence of a disruption in the skin's integrity" and " The infections presented herein include impetigo, ecthyma, folliculitis, carbuncles/furuncles, cellulitis, toxic shock syndrome, and ecthyma gangrenosum"(4).
The differentiation hinted that people with carbuncle are also susceptible to the onset of skin disease.
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the searching of the natural ingredient to replace the use of antibiotics in the treatment of bacterial infection of carbuncle, researchers at the J the Rockefeller University found that epigallocatechin-3-gallate isolated from green tea extracts exerts a significant effect in inhibiting the activity of Staphylococcus aureus (S. aureus), a leading candidate in exhibited risk of carbuncle.
Further analysis also suggested that application EGCG inhibited the Typhimurium type III protein effectors in restriction of bacterial invasion into tested cells.
The type III secretion system of Salmonella typhimurium is found to have a direct effect in the translocation of proteins into host cells in initiated infection.
Dr. Tsou LK, the lead authors said, "These results reveal additional dietary plant metabolites that can attenuate bacterial virulence and infection of host cells".
Some researchers at the Mashhad University of Medical Sciences, after lengthy searching for effective agent without inducing intolerant adverse effect for treatment of bacterial infection, found that green tea catechins, the major green tea polyphenols, shows antimicrobial activity against resistant pathogens, including Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
In compared of catechins, green tea extract, and methylxanthines in combination with gentamicin against standard and clinical isolates, inhibited bacterial activities by a minimum inhibitory concentration (MICs) of gentamicin in the range of 0.312 - 320 μg/mL and The MIC values of both types of catechins were 62.5 - 250 μg/ mL. in compared to no effect in methylxanthines application.
Interestingly, the dose of gentamicin was reduced substantially if adding doses of green tea extract and catechin according to the MICs.
These results indicated that green extract and major bioactive polyphenol catechin may be used alone or combined with gentamicin for treatment of bacterial infection, including carbuncle without inducing the g adverse effect.
Dr. Fazly Bazzaz BS, the lead scientist after taking into account of other co and confounders said, "green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains" and "combinations of gentamicin with these natural compounds might be a promising approach to combat microbial resistance".
Additionally, the evaluate the antibacterial activity of the Indonesian water-soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa conducted by theUniversity of Indonesia suggested
* The inhibition zone diameters of green tea extracts for S. aureus ATCC 25923 and MRSA were 18.970 ± 0.287 mm, and (19.130 ± 0.250) mm respectively.
* The inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
*The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
And
* The MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa was 800 µg/mL, and 800 µg/mL, respectively.
Taking all together, green tea extract and its bioactive polyphenol catechin may be considered as a functional food in reduced risk and treatment of carbuncle caused by Staphylococcus aureus (S. aureus).
Howvwer, intake of green tea extract should be taken with extreme care as acute liver toxicity has been reported by numbers of medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells by Tsou LK1, Yount JS2, Hang HC3.(PubMed)
(2) Effect of Catechins, Green tea Extract and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
(4) Common bacterial skin infections by Trent JT1, Federman D, Kirsner RS(PubMed)
Carbuncle is a collection of boils developed under the skin caused by bacterial infection of hair follicles in the induction of swelling.
Although the infections are most likely developing on the follicles of the hair, they can also appear on other areas of the body such as the buttocks, thighs, groin, and armpits.
Researchers suggested that people who are older age, obesity, poor hygiene, and poor health are most likely associated with increased risk of carbuncles.
However, chronic skin conditions, chronic kidney disease,.... and liver disease are also increased the prevalent risk of the infection.
According to University of Miami School of Medicine, "Skin infections account for a significant portion of dermatologic disease, often resulting in or as a consequence of a disruption in the skin's integrity" and " The infections presented herein include impetigo, ecthyma, folliculitis, carbuncles/furuncles, cellulitis, toxic shock syndrome, and ecthyma gangrenosum"(4).
The differentiation hinted that people with carbuncle are also susceptible to the onset of skin disease.
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the searching of the natural ingredient to replace the use of antibiotics in the treatment of bacterial infection of carbuncle, researchers at the J the Rockefeller University found that epigallocatechin-3-gallate isolated from green tea extracts exerts a significant effect in inhibiting the activity of Staphylococcus aureus (S. aureus), a leading candidate in exhibited risk of carbuncle.
Further analysis also suggested that application EGCG inhibited the Typhimurium type III protein effectors in restriction of bacterial invasion into tested cells.
The type III secretion system of Salmonella typhimurium is found to have a direct effect in the translocation of proteins into host cells in initiated infection.
Dr. Tsou LK, the lead authors said, "These results reveal additional dietary plant metabolites that can attenuate bacterial virulence and infection of host cells".
Some researchers at the Mashhad University of Medical Sciences, after lengthy searching for effective agent without inducing intolerant adverse effect for treatment of bacterial infection, found that green tea catechins, the major green tea polyphenols, shows antimicrobial activity against resistant pathogens, including Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
In compared of catechins, green tea extract, and methylxanthines in combination with gentamicin against standard and clinical isolates, inhibited bacterial activities by a minimum inhibitory concentration (MICs) of gentamicin in the range of 0.312 - 320 μg/mL and The MIC values of both types of catechins were 62.5 - 250 μg/ mL. in compared to no effect in methylxanthines application.
Interestingly, the dose of gentamicin was reduced substantially if adding doses of green tea extract and catechin according to the MICs.
These results indicated that green extract and major bioactive polyphenol catechin may be used alone or combined with gentamicin for treatment of bacterial infection, including carbuncle without inducing the g adverse effect.
Dr. Fazly Bazzaz BS, the lead scientist after taking into account of other co and confounders said, "green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains" and "combinations of gentamicin with these natural compounds might be a promising approach to combat microbial resistance".
Additionally, the evaluate the antibacterial activity of the Indonesian water-soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa conducted by theUniversity of Indonesia suggested
* The inhibition zone diameters of green tea extracts for S. aureus ATCC 25923 and MRSA were 18.970 ± 0.287 mm, and (19.130 ± 0.250) mm respectively.
* The inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
*The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
And
* The MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa was 800 µg/mL, and 800 µg/mL, respectively.
Taking all together, green tea extract and its bioactive polyphenol catechin may be considered as a functional food in reduced risk and treatment of carbuncle caused by Staphylococcus aureus (S. aureus).
Howvwer, intake of green tea extract should be taken with extreme care as acute liver toxicity has been reported by numbers of medical literature.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells by Tsou LK1, Yount JS2, Hang HC3.(PubMed)
(2) Effect of Catechins, Green tea Extract and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
(4) Common bacterial skin infections by Trent JT1, Federman D, Kirsner RS(PubMed)
Thursday, October 10, 2019
Lycopene, Protects the Liver Cells Against the Risk of Hepatic Steatosis
The liver is the largest internal organ that filters the blood from the digestive tract, before passing them to the rest of the body.
The liver also plays an essential role to produce cholesterol to build a strong cell wall, produce steroid hormones and vitamin D and aid the digestive function in food absorption and detoxify chemicals and metabolizes drugs.
Hepatic steatosis is a medical condition that reduces the function of the liver caused by the accumulation of fat in the liver.
In other words, if the intrahepatic fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Epidemiologically, over time, untreated hepatic steatosis can lead to liver metabolic dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease.
Hepatic steatosis has been found to induce complications in patients with obesity, alcohol intoxication and/or hepatic disorders.
Most common risk factors associated with the onset of hepatic steatosis are insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN).
The increased flux of fatty acids to the liver, de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion are some mechanisms that cause the accumulation of intrahepatic fat.
Out of many prevalent factors involved in the onset of hepatic steatosis, some researchers suggested that the promotion of the Western diet over the past few decades in the Western world may have a strong and negative impact that accelerates the incidence onset.
Dr. Michael D. Roberts, the lead scientist said, "Six weeks of WD feeding caused hepatic steatosis development as evidenced by the 2.25-fold increase in liver triacylglycerol content,...in adult Brown Norway rats".
And, "sub-chronic WD feeding appears to increase hepatic steatosis development over a 6-week period but only induces select inflammation-related liver transcripts, mostly acute phase response genes".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the prevention of liver disease, researchers examined the effects of lycopene on hepatic steatosis in an animal model.
In a model of high-fat diet rats, lycopene not only showed a significant effect against the development of steatohepatitis but also inhibited nonalcoholic steatohepatitis (NASH) in the promotion of the early stage of liver cancer through its antioxidant activity.
In rats induced NAFLD by a hypercholesterolemic and high-fat diet, according to the tested analysis, after 7 weeks, there are clear differences in the classical antioxidant biomarkers and metabolic pattern associated with the inhibition of NAFLD between the diet and intake of lycopene from tomato juice.
Interestingly, tomato juice administration partially reverted the metabolic pattern from a high-fat diet to a normal diet in metabolites without exhibiting the redox state.
Taken altogether, lycopene found in tomato may be considered supplements for the improvement of liver metabolism against the risk liver disease, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months)
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ. (PubMed)
(2) Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice by Ip BC1, Liu C2, Lichtenstein AH3, von Lintig J4, Wang XD. (PubMed)
(3) Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown Norway rats by Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu,Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins,Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth, and R. Scott Rector. (PMC)
The liver also plays an essential role to produce cholesterol to build a strong cell wall, produce steroid hormones and vitamin D and aid the digestive function in food absorption and detoxify chemicals and metabolizes drugs.
Hepatic steatosis is a medical condition that reduces the function of the liver caused by the accumulation of fat in the liver.
In other words, if the intrahepatic fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Epidemiologically, over time, untreated hepatic steatosis can lead to liver metabolic dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease.
Hepatic steatosis has been found to induce complications in patients with obesity, alcohol intoxication and/or hepatic disorders.
Most common risk factors associated with the onset of hepatic steatosis are insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN).
The increased flux of fatty acids to the liver, de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion are some mechanisms that cause the accumulation of intrahepatic fat.
Out of many prevalent factors involved in the onset of hepatic steatosis, some researchers suggested that the promotion of the Western diet over the past few decades in the Western world may have a strong and negative impact that accelerates the incidence onset.
Dr. Michael D. Roberts, the lead scientist said, "Six weeks of WD feeding caused hepatic steatosis development as evidenced by the 2.25-fold increase in liver triacylglycerol content,...in adult Brown Norway rats".
And, "sub-chronic WD feeding appears to increase hepatic steatosis development over a 6-week period but only induces select inflammation-related liver transcripts, mostly acute phase response genes".
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the prevention of liver disease, researchers examined the effects of lycopene on hepatic steatosis in an animal model.
In a model of high-fat diet rats, lycopene not only showed a significant effect against the development of steatohepatitis but also inhibited nonalcoholic steatohepatitis (NASH) in the promotion of the early stage of liver cancer through its antioxidant activity.
In rats induced NAFLD by a hypercholesterolemic and high-fat diet, according to the tested analysis, after 7 weeks, there are clear differences in the classical antioxidant biomarkers and metabolic pattern associated with the inhibition of NAFLD between the diet and intake of lycopene from tomato juice.
Interestingly, tomato juice administration partially reverted the metabolic pattern from a high-fat diet to a normal diet in metabolites without exhibiting the redox state.
Taken altogether, lycopene found in tomato may be considered supplements for the improvement of liver metabolism against the risk liver disease, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months)
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ. (PubMed)
(2) Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice by Ip BC1, Liu C2, Lichtenstein AH3, von Lintig J4, Wang XD. (PubMed)
(3) Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown Norway rats by Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu,Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins,Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth, and R. Scott Rector. (PMC)
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