The bacterial infection is the inflammation caused by the multiplication of bacterias after entering the body successfully.
The process of infection can be divided into many stages. However, most bacterias that try to invade the body were killed in the acute phase of infection by the immune system response through the production of the pro-inflammatory cytokines stimulated by the white blood cell macrophages.
According to the statistic provided by the CDC, each year in the U.S., at least 2 million people get an antibiotic-resistant infection, and at least 23,000 people die due to bacterial infectious disease.
Most people do not experience any symptoms until the microbe multiplication to the peak in its’ population.
Acute infection in most cases is recovered with a week or two. However, if the immune function cannot destroy all the bacterias within 3 to 8 weeks, it will compromise, leading to chronic low-grade inflammatory diseases.
Most common and classical symptoms of acute infection are aches, pains, fever, malaise, and nausea.
The chronic low-grade inflammatory state is a pathological feature of a wide range of chronic conditions, such as metabolic syndrome (MetS), non-alcoholic fatty liver disease (NAFLD), type 2 diabetes.
A most common risk of bacterial infection is a weakened immune system, particularly in the elderly.
The Institute of Medicine (US) Division of Health Promotion and Disease Prevention in examing the risk of infection in elderly, wrote, "The implications of an aging population for health care are being widely discussed but seldom with the understanding that health promotion and disability prevention are workable concepts for people in the “second 50” years of life".
And, "Pneumonia and influenza are among the leading causes of death and morbidity from infection among older people. Safe and effective vaccines to prevent pneumonia and influenza are available and should be universally used in persons over age 50. Nosocomial (institutionally acquired) infections have a major deleterious impact on persons over 50 and require good infection control practices in hospitals and nursing homes".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of bacterial infection, researchers examined the effect of the flower bud extract of Tussilago farfara on Gram-positive and Gram-negative bacteria.
The study is to compare the antibacterial activity of silver and gold nanoparticles of sesquiterpenoids from T. farfara flower bud extract and the use of extract alone.
According to the tested analysis, the silver nanoparticles exerted a two- to the four-fold enhancement of the extract comapred to the extract alone in the treatment of both Gram-positive and Gram-negative bacteria.
The solver nanoparticles also showed the highest antibacterial activity against vancomycin-resistant Enterococci Van-A type Enterococcus faecium, comapred to the extract alone.
Based on the findings, researchers said, " both nanoparticles synthesized with the sesquiterpenoids from T. farfara flower bud extract can be applied as drug delivery vehicles of anticancer or antibacterial agents for future nanomedicine applications.s".
Taken altogether, coltsfoot and silver and gold nanoparticles of sesquiterpenoids from T. farfara flower bud extract may be considered remedies for the treatment of bacterial infection, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Chemical composition and antibacterial activity of Tussilago farfara (L.) essential oil from Quebec, Canada by Boucher MA1, Côté H1, Pichette A1, Ripoll L1, Legault J. (PubMed)
(2) Sesquiterpenoids from Tussilago farfara Flower Bud Extract for the Eco-Friendly Synthesis of Silver and Gold Nanoparticles Possessing Antibacterial and Anticancer Activities by Lee YJ1, Song K2, Cha SH3, Cho S4, Kim YS5, Park Y. (PubMed)
(3) The Second Fifty Years by Promoting Health and Preventing Disability (1992). (NCBI)
Friday, October 18, 2019
Thursday, October 17, 2019
Healthy Food Onion in the Inhibition of Angiogenesis
Angiogenesis is the process that promotes the formation of new blood vessels involving many factors including the migration, growth, and differentiation of endothelial cells.
In normal cells, angiogenesis is important for the cells to obtain nutrients and metabolites through the small blood vessels. Angiogenesis has been found to process a therapeutic effect for the treatment of ischemic heart disease, peripheral arterial disease, and wound healing.
Dr. Papetti M, the lead scientist at the Tufts University School of Medicine said, "Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients".
In cancers, angiogenesis stimulated by the tumor cells has been associated with tumors proliferation and metastasis.
More precisely, the angiogenesis process a function of a double sword, on one hand, the process provides an ideal condition for the treatment of diseases and wound healing. On the other hand, it promotes invasive and overgrowth tumors.
Dr. Papetti M continued, "tumor cells induce the formation of new blood supply from the preexisting vasculature, and this affords tumor cells the ability to survive and propagate in a hostile environment"
Collectively, " both normal and tumor-induced neovascularization fulfill the essential role of satisfying the metabolic demands of tissue".
Based on the findings some researchers suggested, by inhibiting the process of blood vessels formation of the tumor, cancer may be curable.
Dr. Dai X, the lead researchers in the study of "Suppression of murine B-cell lymphoma growth by trichosanthin through anti-angiogenesis" showed, "trichosanthin TCS, ( an immunosuppressive and anti-tumor protein) inhibits murine B-cell lymphoma growth by anti-angiogenesis was reported. First, TCS inhibits tumor growth and prolonged survival significantly in vivo, and TCS depressed the formation of new blood vessels around the tumor in a dose-dependent manner".
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potent ingredient that processes anti-cancer activity researchers studied the antiangiogenic activity of quercetin isolated from onion, using ex vivo, in vivo and in vitro models.
According to the tested differentiation, quercetin at non-toxic concentrations significantly inhibited the microvessel sprouting associated with cancer cell proliferation.
Furthermore, the activity of cancer cells migration, invasion and tube formation of endothelial cells involved in the process of angiogenesis.was also significantly decreased by the administration of quercetin.
Quercetin treatment inhibited ex vivo angiogenesis observed by chicken egg chorioallantoic membrane assay (CAM) and matrigel plug assay.
Moreover, quercetin suppressed vascular endothelial growth factor (VEGF) which has been found to induce the formation of a blood vessel for the progression of the tumor.
Additionally, downstream pathways associated with the promotion of survival and growth in response to extracellular signals that induce angiogenesis were also inhibited by quercetin in HUVECs.
Quercetin at the concentration of 20 mg/kg/d significantly reduced the volume and the weight of solid tumors in a prostate xenograft mouse model by targeting angiogenesis.
Quercetin was also found to inhibited the cancer cell viability and induced apoptosis in prostate cancer cells.
In other words, quercetin inhibits tumor growth and angiogenesis by targeting the proteins and signaling pathways that initiate the growth of new blood vessels.
Taken altogether, onion processed a higher mount of quercetin may be considered a remedy for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways by Poyil Pratheeshkumar, Amit Budhraja, Young-Ok Son, Xin Wang, Zhuo Zhang, Songze Ding, Lei Wang, Andrew Hitron, Jeong-Chae Lee, Mei Xu, Gang Chen, Jia Luo, and Xianglin Shi. (Plos One)
(2) Suppression of murine B-cell lymphoma growth by trichosanthin through anti-angiogenesis by Dai X1,2, Jiang P2, Ji Y3, Zhu X2, Sun X. (PubMed)
In normal cells, angiogenesis is important for the cells to obtain nutrients and metabolites through the small blood vessels. Angiogenesis has been found to process a therapeutic effect for the treatment of ischemic heart disease, peripheral arterial disease, and wound healing.
Dr. Papetti M, the lead scientist at the Tufts University School of Medicine said, "Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients".
In cancers, angiogenesis stimulated by the tumor cells has been associated with tumors proliferation and metastasis.
More precisely, the angiogenesis process a function of a double sword, on one hand, the process provides an ideal condition for the treatment of diseases and wound healing. On the other hand, it promotes invasive and overgrowth tumors.
Dr. Papetti M continued, "tumor cells induce the formation of new blood supply from the preexisting vasculature, and this affords tumor cells the ability to survive and propagate in a hostile environment"
Collectively, " both normal and tumor-induced neovascularization fulfill the essential role of satisfying the metabolic demands of tissue".
Based on the findings some researchers suggested, by inhibiting the process of blood vessels formation of the tumor, cancer may be curable.
Dr. Dai X, the lead researchers in the study of "Suppression of murine B-cell lymphoma growth by trichosanthin through anti-angiogenesis" showed, "trichosanthin TCS, ( an immunosuppressive and anti-tumor protein) inhibits murine B-cell lymphoma growth by anti-angiogenesis was reported. First, TCS inhibits tumor growth and prolonged survival significantly in vivo, and TCS depressed the formation of new blood vessels around the tumor in a dose-dependent manner".
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potent ingredient that processes anti-cancer activity researchers studied the antiangiogenic activity of quercetin isolated from onion, using ex vivo, in vivo and in vitro models.
According to the tested differentiation, quercetin at non-toxic concentrations significantly inhibited the microvessel sprouting associated with cancer cell proliferation.
Furthermore, the activity of cancer cells migration, invasion and tube formation of endothelial cells involved in the process of angiogenesis.was also significantly decreased by the administration of quercetin.
Quercetin treatment inhibited ex vivo angiogenesis observed by chicken egg chorioallantoic membrane assay (CAM) and matrigel plug assay.
Moreover, quercetin suppressed vascular endothelial growth factor (VEGF) which has been found to induce the formation of a blood vessel for the progression of the tumor.
Additionally, downstream pathways associated with the promotion of survival and growth in response to extracellular signals that induce angiogenesis were also inhibited by quercetin in HUVECs.
Quercetin at the concentration of 20 mg/kg/d significantly reduced the volume and the weight of solid tumors in a prostate xenograft mouse model by targeting angiogenesis.
Quercetin was also found to inhibited the cancer cell viability and induced apoptosis in prostate cancer cells.
In other words, quercetin inhibits tumor growth and angiogenesis by targeting the proteins and signaling pathways that initiate the growth of new blood vessels.
Taken altogether, onion processed a higher mount of quercetin may be considered a remedy for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways by Poyil Pratheeshkumar, Amit Budhraja, Young-Ok Son, Xin Wang, Zhuo Zhang, Songze Ding, Lei Wang, Andrew Hitron, Jeong-Chae Lee, Mei Xu, Gang Chen, Jia Luo, and Xianglin Shi. (Plos One)
(2) Suppression of murine B-cell lymphoma growth by trichosanthin through anti-angiogenesis by Dai X1,2, Jiang P2, Ji Y3, Zhu X2, Sun X. (PubMed)
Green tea, The Beverage Which Processes Anti Viral Activity Against Onset of Pneumonitis
Scientists may have found a beverage processed antivirus property for a cure of pneumonitis, some studies suggested.
Pneumonitis is an inflammatory disease that affects the walls of the alveoli in the lungs, in most cases, it is caused by a virus.
However, irritants, ranging from airborne molds to chemotherapy drugs, have been linked to the onset of the condition.
Most common symptoms of are difficulty breathing, often accompanied by a dry cough.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
In the concerns of the widespread of some virus in the induction of pneumonitis, researchers at the Kobe University conducted an investigation to examine whether green tea Epigallocatechin-3-O-gallate (EGCG), the major catechin component of green tea possessed antiviral activities against a wide range of DNA viruses and RNA viruses, that cause pneumonitis.
At the final report of the experiment, researchers suggested that EGCG appears most likely to inhibits the early stage of infections, such as attachment, entry, and membrane fusion, by interfering with viral membrane proteins.
Also, according to the observation of the relationships between structure and antiviral activity of catechin derivatives, researchers found that the 3-galloyl and 5'-OH group of catechin derivatives appears critical to antiviral activities in the early phase of infection.
In addition of fatty acid derivative, the combination also exerts an increase viral and cellular membrane permeability.
These results suggested that EGCG-fatty acid monoesters improved greater antiviral activities against different types of viruses, probably due to their increased affinity for virus and cellular membranes, compared to the use of EGCG alone.
Dr. Kaihatsu K, the lead author said, after taking into account of other co and confounders, "(The) application of EGCG-fatty acid derivatives for the prevention and treatment of viral infections".
Furthermore, a study in the evaluation of epigallocatechin-3-gallate (EGCG), the main constituent of green tea, anti-infective properties.launched by the University of Duisburg-Essen, showed that application of EGCG demonstrated a significant activity on orthomyxoviridae and Flaviviridae and other human pathogens like human immunodeficiency virus, influenza A virus and the hepatitis C virus.through interfering with the replication cycle of DNA viruses like hepatitis B virus, herpes simplex virus,.... and adenovirus.
Additionally, in an experimental skin contact model for influenza virus transmission to evaluate the use of a green tea solution as a first-hand disinfectant, researchers strong agreed that green tea displays a strong antiviral effect in inhibiting the infectivity of the virus on the skin cell layer.
This result suggested that green tea may be used as a non-pharmaceutical washing solution in reducing human transmission of viral infection, including the virus that causes pneumonitis.
Taken all together, green tea and its bioactive EGCG may be considered a functional food in protecting the lung tissue against the onset of viral pneumonitis.
Intake of green tea supplement EGCG should be taken with extreme care as acute liver diseases have been reported in many instances.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antiviral Mechanism of Action of Epigallocatechin-3-O-gallate and Its Fatty Acid Esters by Kaihatsu K1, Yamabe M2, Ebara Y. (PubMed)
(2) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by Steinmann J1, Buer J, Pietschmann T, Steinmann E.(PubMed)
(3) Evaluation of the antiviral activity of a green tea solution as a hand-wash disinfectant by Shin WJ1, Kim YK, Lee KH, Seong BL. (PubMed)
Pneumonitis is an inflammatory disease that affects the walls of the alveoli in the lungs, in most cases, it is caused by a virus.
However, irritants, ranging from airborne molds to chemotherapy drugs, have been linked to the onset of the condition.
Most common symptoms of are difficulty breathing, often accompanied by a dry cough.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.
In the concerns of the widespread of some virus in the induction of pneumonitis, researchers at the Kobe University conducted an investigation to examine whether green tea Epigallocatechin-3-O-gallate (EGCG), the major catechin component of green tea possessed antiviral activities against a wide range of DNA viruses and RNA viruses, that cause pneumonitis.
At the final report of the experiment, researchers suggested that EGCG appears most likely to inhibits the early stage of infections, such as attachment, entry, and membrane fusion, by interfering with viral membrane proteins.
Also, according to the observation of the relationships between structure and antiviral activity of catechin derivatives, researchers found that the 3-galloyl and 5'-OH group of catechin derivatives appears critical to antiviral activities in the early phase of infection.
In addition of fatty acid derivative, the combination also exerts an increase viral and cellular membrane permeability.
These results suggested that EGCG-fatty acid monoesters improved greater antiviral activities against different types of viruses, probably due to their increased affinity for virus and cellular membranes, compared to the use of EGCG alone.
Dr. Kaihatsu K, the lead author said, after taking into account of other co and confounders, "(The) application of EGCG-fatty acid derivatives for the prevention and treatment of viral infections".
Furthermore, a study in the evaluation of epigallocatechin-3-gallate (EGCG), the main constituent of green tea, anti-infective properties.launched by the University of Duisburg-Essen, showed that application of EGCG demonstrated a significant activity on orthomyxoviridae and Flaviviridae and other human pathogens like human immunodeficiency virus, influenza A virus and the hepatitis C virus.through interfering with the replication cycle of DNA viruses like hepatitis B virus, herpes simplex virus,.... and adenovirus.
Additionally, in an experimental skin contact model for influenza virus transmission to evaluate the use of a green tea solution as a first-hand disinfectant, researchers strong agreed that green tea displays a strong antiviral effect in inhibiting the infectivity of the virus on the skin cell layer.
This result suggested that green tea may be used as a non-pharmaceutical washing solution in reducing human transmission of viral infection, including the virus that causes pneumonitis.
Taken all together, green tea and its bioactive EGCG may be considered a functional food in protecting the lung tissue against the onset of viral pneumonitis.
Intake of green tea supplement EGCG should be taken with extreme care as acute liver diseases have been reported in many instances.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antiviral Mechanism of Action of Epigallocatechin-3-O-gallate and Its Fatty Acid Esters by Kaihatsu K1, Yamabe M2, Ebara Y. (PubMed)
(2) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by Steinmann J1, Buer J, Pietschmann T, Steinmann E.(PubMed)
(3) Evaluation of the antiviral activity of a green tea solution as a hand-wash disinfectant by Shin WJ1, Kim YK, Lee KH, Seong BL. (PubMed)
Wednesday, October 16, 2019
Green Tea and Its Bioactive EGCG Which Process Anti Bacterial Activity Against the Onset of Atypical Pneumonia, Scientist Find
Green tea may have a therapeutic and positive effect in protecting the lung against bacterias that cause atypical pneumonia, some scientists suggested.
Atypical pneumonia is an infection of the lower respiratory tract. The disease is accounted for 7%‐20% of community‐acquired pneumonia (CAP).
Most cases of atypical pneumonia are caused by Streptococcus pneumonia. However, Other bacteria such as Mycoplasma pneumonia, Chlamydia pneumonia, Chlamydia psittaci, and Legionella pneumophila are also found in some patients with atypical pneumonia.
Conventional medicine used for the treatment of typical pneumonia, such as Macrolide antibiotics: Macrolide drugs are the preferred treatment for children and adults. Macrolides include azithromycin(Zithromax®) and clarithromycin may be effective. However, they can induce certain side effects including gastrointestinal discomforts.
The article of Popular Antibiotics May Carry Serious Side Effects BY JANE E. BRODY, in the explanation of a patient who just took on dose of antibiotic, wrote," After just one dose, he developed widespread pain and weakness." and " (He is) unable to walk uphill, climb stairs or see clearly, his symptoms included dry eyes, mouth, and skin; ringing in his ears; delayed urination; uncontrollable shaking; burning pain in his eyes and feet; occasional tingling in his hands and feet; heart palpitations; and muscle spasms in his back and around his eyes".
If you are currently taking antibiotics for the treatment of a disease, please make sure that you discuss the side effects with your doctor.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
With an aim to find the natural solution with antibacterial potential, researchers at the University of Duisburg-Essen conducted a study to examine whether green tea processes antibacterial activity against the onset of infectious diseases.
At the final report of the experiment, researchers wrote, the minimum inhibitory concentrations against bacteria were 10–100-fold higher compared to the antiviral property with the same volume.
EGCG used alone or in combination with different antibiotics exerts a significant activity against a number of bacteria including multidrug-resistant strains such as methicillin-resistant Staphylococcus aureus Stenotrophomonas maltophilia, the group of bacteria that cause atypical pneumonia.
The additional analysis suggested that EGCG displays the efficacy in inhibiting bacteria by binding to lipid membranes and affecting the folic acid metabolism of bacteria and fungi by inhibiting the cytoplasmic enzyme dihydrofolate reductase.
Dihydrofolate reductase, or DHFR, an enzyme that reduces hydrofolic acid to tetrahydrofolic acid, plays an essential role in the building of DNA of the cells.
Furthermore, in an aim to find a natural anti antibacterial remedy in replacing the ineffective antibiotics as well as the concerns over the toxicity of the mainstay of treatment against Stenotrophomonas maltophilia, a main cause of atypical pneumonia, researchers at the Barts & The London NHS Trust conducted a study to examine the effect of Epigallocatechin-3-gallate (EGCG), the major catechin found in green tea,against a number of bacteria.
In a total of 40 clinical isolates of S. maltophilia used in the experiment, scientists found that EGCG exerts a promising in vitro antimicrobial activity against S. maltophilia. At the dose of 512 mg/ L., EGCG inhibited bacteria in the range of 50% and 90%.
Moreover, in the examination of tea leaves organic compounds involved in the defense of the plants against invading pathogens including insects, bacteria, fungi, and viruses, researchers showed that tea flavonoids and teas exert great antimicrobial effects against foodborne and other pathogenic bacteria, virulent protein toxins produced by some of the bacteria, virulent bacteriophages, pathogenic viruses, and fungi.
Taken all together, green tea and its bioactive ingredient EGCG may be considered a functional food and supplement respectively in protecting the human body against bacteria, particularly, Streptococcus pneumonia in the initiation of the onset of bacterial infection and infectious diseases, including atypical pneumonia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by J Steinmann,1 J Buer,1 T Pietschmann,2 and E Steinmann(PMC)
(2) Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia by Gordon NC1, Wareham DW(PubMed)
(3) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas Mendel Friedman
Atypical pneumonia is an infection of the lower respiratory tract. The disease is accounted for 7%‐20% of community‐acquired pneumonia (CAP).
Most cases of atypical pneumonia are caused by Streptococcus pneumonia. However, Other bacteria such as Mycoplasma pneumonia, Chlamydia pneumonia, Chlamydia psittaci, and Legionella pneumophila are also found in some patients with atypical pneumonia.
Conventional medicine used for the treatment of typical pneumonia, such as Macrolide antibiotics: Macrolide drugs are the preferred treatment for children and adults. Macrolides include azithromycin(Zithromax®) and clarithromycin may be effective. However, they can induce certain side effects including gastrointestinal discomforts.
The article of Popular Antibiotics May Carry Serious Side Effects BY JANE E. BRODY, in the explanation of a patient who just took on dose of antibiotic, wrote," After just one dose, he developed widespread pain and weakness." and " (He is) unable to walk uphill, climb stairs or see clearly, his symptoms included dry eyes, mouth, and skin; ringing in his ears; delayed urination; uncontrollable shaking; burning pain in his eyes and feet; occasional tingling in his hands and feet; heart palpitations; and muscle spasms in his back and around his eyes".
If you are currently taking antibiotics for the treatment of a disease, please make sure that you discuss the side effects with your doctor.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
With an aim to find the natural solution with antibacterial potential, researchers at the University of Duisburg-Essen conducted a study to examine whether green tea processes antibacterial activity against the onset of infectious diseases.
At the final report of the experiment, researchers wrote, the minimum inhibitory concentrations against bacteria were 10–100-fold higher compared to the antiviral property with the same volume.
EGCG used alone or in combination with different antibiotics exerts a significant activity against a number of bacteria including multidrug-resistant strains such as methicillin-resistant Staphylococcus aureus Stenotrophomonas maltophilia, the group of bacteria that cause atypical pneumonia.
The additional analysis suggested that EGCG displays the efficacy in inhibiting bacteria by binding to lipid membranes and affecting the folic acid metabolism of bacteria and fungi by inhibiting the cytoplasmic enzyme dihydrofolate reductase.
Dihydrofolate reductase, or DHFR, an enzyme that reduces hydrofolic acid to tetrahydrofolic acid, plays an essential role in the building of DNA of the cells.
Furthermore, in an aim to find a natural anti antibacterial remedy in replacing the ineffective antibiotics as well as the concerns over the toxicity of the mainstay of treatment against Stenotrophomonas maltophilia, a main cause of atypical pneumonia, researchers at the Barts & The London NHS Trust conducted a study to examine the effect of Epigallocatechin-3-gallate (EGCG), the major catechin found in green tea,against a number of bacteria.
In a total of 40 clinical isolates of S. maltophilia used in the experiment, scientists found that EGCG exerts a promising in vitro antimicrobial activity against S. maltophilia. At the dose of 512 mg/ L., EGCG inhibited bacteria in the range of 50% and 90%.
Moreover, in the examination of tea leaves organic compounds involved in the defense of the plants against invading pathogens including insects, bacteria, fungi, and viruses, researchers showed that tea flavonoids and teas exert great antimicrobial effects against foodborne and other pathogenic bacteria, virulent protein toxins produced by some of the bacteria, virulent bacteriophages, pathogenic viruses, and fungi.
Taken all together, green tea and its bioactive ingredient EGCG may be considered a functional food and supplement respectively in protecting the human body against bacteria, particularly, Streptococcus pneumonia in the initiation of the onset of bacterial infection and infectious diseases, including atypical pneumonia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by J Steinmann,1 J Buer,1 T Pietschmann,2 and E Steinmann(PMC)
(2) Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia by Gordon NC1, Wareham DW(PubMed)
(3) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas Mendel Friedman
Indicaxanthin, Might Protect the Skin Against Melanoma
The skin is the largest external organ that protects us against infection and physical trauma by guarding the underlying muscles, bones, ligaments, and internal organs.
Furthermore, the skin accompanied by liver and kidney detoxes toxins in the body
Melanoma is a type of skin cancer caused by the alternation of cell DNA in the pigment-containing cells known as melanocytes. Most cases of melanomas are found in the skin.
According to the statistics, approximate 120,000 new cases of melanoma in the US are diagnosed in a year. The skin cancer tends to spread along the skin in most of the cases, but also can grow down to the deeper layers of the skin.
At the advanced stage, skin melanoma can also travel a distance aways to infect other healthy tissues through blood and fluid circulation.
Most common symptoms of melanoma skin cancer are
* Asymmetry
The mole on the skin is no longer symmetric as one half of the mole is different from the other half.
* Borders irregular
The border of the mole has become irregular, such as uneven or notched.
* Color
The color of the mole is different than other moles on the skin.
* Diameter
The mole is larger than other mole and evolved over time
Accompanied by pain, swelling, and bleeding in the affected skin
There are 3 main types of melanoma skin cancer, including
* Superficial spreading
This is the most common type of melanoma, accounting for over 70% of all cases. The cancer cell usually starts with a normal mole, but for whatever reason, it begins to change malignantly with irregular borders and color variations.
* Nodular type
This type of melanoma is more aggressive growth than superficial spreading and found most on the trunk, upper arms, and thighs. The nodular type of melanoma is usually detected as a lump with blue and black color.
* Acral melanoma
Acral melanoma is mostly founded on the hands, feet, and nail beds. The risk increases for people with darken-skin color.
* Lentigo maligna melanoma
Found mostly on the face of the elderly caused by great exposure to sunlight.
Indicaxanthin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.
With an aim to find a potent ingredient for the treatment of cancer, researchers investigated the effects of Indicaxanthin, against human melanoma both in vitro and in vivo.
According to the tested analysis, the growth of A375 cells was inhibited by the injection of the phytochemical
Furthermore, Indicaxanthin also induced apoptosis and decreased the invasiveness of A375 cells.
In other words, indicaxanthin effectively inhibits the proliferation of highly metastatic and invasive and anti-apoptotic activity of the A375 cells.
In mice, induced melanoma, oral administration of Indicaxanthin also significantly reduced tumor developing.
Additional differentiation of the anti-cancer activity of Indicaxanthin, researchers found that the efficacy of the bioactive compound was attributed to the inhibition of the NF-κB pathways associated with the antiproliferative effect of indicaxanthin.
Based on the results, researchers wrote, " indicaxanthin represents a novel phytochemical able to significantly inhibit human melanoma cell proliferation in vitro and to impair tumor progression in vivo".
Taken altogether, indicaxanthin may be considered a remedy for the prevention and treatment of melanoma, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression by Allegra M1, De Cicco P2, Ercolano G2, Attanzio A1, Busà R1, Cirino G2, Tesoriere L1, Livrea MA1, Ianaro A. (PubMed)
(2) Melanoma Skin Cancer (Malignant Melanoma) by Kyle J. Norton
Furthermore, the skin accompanied by liver and kidney detoxes toxins in the body
Melanoma is a type of skin cancer caused by the alternation of cell DNA in the pigment-containing cells known as melanocytes. Most cases of melanomas are found in the skin.
According to the statistics, approximate 120,000 new cases of melanoma in the US are diagnosed in a year. The skin cancer tends to spread along the skin in most of the cases, but also can grow down to the deeper layers of the skin.
At the advanced stage, skin melanoma can also travel a distance aways to infect other healthy tissues through blood and fluid circulation.
Most common symptoms of melanoma skin cancer are
* Asymmetry
The mole on the skin is no longer symmetric as one half of the mole is different from the other half.
* Borders irregular
The border of the mole has become irregular, such as uneven or notched.
* Color
The color of the mole is different than other moles on the skin.
* Diameter
The mole is larger than other mole and evolved over time
Accompanied by pain, swelling, and bleeding in the affected skin
There are 3 main types of melanoma skin cancer, including
* Superficial spreading
This is the most common type of melanoma, accounting for over 70% of all cases. The cancer cell usually starts with a normal mole, but for whatever reason, it begins to change malignantly with irregular borders and color variations.
* Nodular type
This type of melanoma is more aggressive growth than superficial spreading and found most on the trunk, upper arms, and thighs. The nodular type of melanoma is usually detected as a lump with blue and black color.
* Acral melanoma
Acral melanoma is mostly founded on the hands, feet, and nail beds. The risk increases for people with darken-skin color.
* Lentigo maligna melanoma
Found mostly on the face of the elderly caused by great exposure to sunlight.
Indicaxanthin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belongings to the group of Betalains found abundantly in beets, chard, etc.
With an aim to find a potent ingredient for the treatment of cancer, researchers investigated the effects of Indicaxanthin, against human melanoma both in vitro and in vivo.
According to the tested analysis, the growth of A375 cells was inhibited by the injection of the phytochemical
Furthermore, Indicaxanthin also induced apoptosis and decreased the invasiveness of A375 cells.
In other words, indicaxanthin effectively inhibits the proliferation of highly metastatic and invasive and anti-apoptotic activity of the A375 cells.
In mice, induced melanoma, oral administration of Indicaxanthin also significantly reduced tumor developing.
Additional differentiation of the anti-cancer activity of Indicaxanthin, researchers found that the efficacy of the bioactive compound was attributed to the inhibition of the NF-κB pathways associated with the antiproliferative effect of indicaxanthin.
Based on the results, researchers wrote, " indicaxanthin represents a novel phytochemical able to significantly inhibit human melanoma cell proliferation in vitro and to impair tumor progression in vivo".
Taken altogether, indicaxanthin may be considered a remedy for the prevention and treatment of melanoma, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression by Allegra M1, De Cicco P2, Ercolano G2, Attanzio A1, Busà R1, Cirino G2, Tesoriere L1, Livrea MA1, Ianaro A. (PubMed)
(2) Melanoma Skin Cancer (Malignant Melanoma) by Kyle J. Norton
Tuesday, October 15, 2019
Herbal Turmeric Destroys Oral Cancer Cells in Vitro
The stomach that secretes acid and enzymes to digest food is a muscular organ located on the left side of the upper abdomen.
Foods that reach the end of the esophagus enters the stomach through a muscular valve called the lower esophageal sphincter.
The stomach not only forms part of the digestive system, but it also is the first organ to digest foods.
Oral/ Stomach cancer is a group of cancer characterized by malignant cell growth in the tissue located in the oral cavity, including the tissue of the lips or the tongue, cheek lining, floor of the mouth, gums (gingiva) and the roof of the mouth (palate).
According to worldwide statistics, oral cancer is the 11th most common malignancy in the world. There is a global trend of a slight decrease in the incidence of oral cancer, except for tongue cancer.
In the US, 53,000 Americans will be diagnosed with oral or oropharyngeal cancer in 2019. Oral cancer also will cause the death of over 9,750 Americans.
Patients with oral cancer depending on the stage and grade may experience general symptoms shared by other types of cancer such as unintended weight loss of over 10%, loss of appetite, persistent fatigue and nausea and vomiting accompanied by
* Poorly healing mouth ulcer
Poorly healing mouth ulcer indicates something wrong within the cells and can be cancerous if left untreated for a prolonged period of time.
*A sore that does not heal on the lip or in the mouth
If the ulcer does not heal with 2 weeks, it may be a sign of abnormal cell growth or tumor.
* A lump or thickening in the oral cavity
Due to cell growth irregularity.
* Patches that are white or red (or both) inside the mouth or on the lips
Maybe due to infection or inflammation.
* Loose teeth
Maybe due to inflammation of gingivitis
*Dentures that not fit well
It increases the risk of infection and gum damage.
* Problems speaking clearly
* A lump in the neck
Cancer has spread to the lymph nodes in the neck region.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the oral cancer possibility.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a potential ingredient for the treatment of oral cancer associated with squamous cells, researchers examined the effect of curcumin on oral squamous cell carcinoma (OSCC).
According to the tested differentiation, the expression levels of miR-9 were significantly lower in clinical OSCC specimens compared to non-tumor tissues.
Where miR-9 is a microRNA involved in cancer cell arrest and apoptosis.
Administration of curcumin inhibited OSCC cells (SCC-9 cells) proliferation by exhibiting the miR-9 expression and suppressing Wnt/β-catenin signaling associated with the promotion of cancer progression by regulating the tumor-immune cycle.
Additional analysis of the interaction of signaling pathways suggested that the mechanisms that regulate the gene expression such as GSK-3β, phosphorylated GSK-3β and β-catenin associated with the inhibition of Wnt/β-catenin signaling pathway were also increased by the application of curcumin.
Furthermore, Cyclin D1 involved in the promotion of cell cycle progression in the tested cell line was also decreased by curcumin injection.
In Micro RNA analysis, reduced expression of miR-9 by anti-miR-9 not only attenuated the growth-suppressive effects of curcumin on SCC-9 cells but also re-activated Wnt/β-catenin signaling that was inhibited by curcumin.
In other words, curcumin inhibited the initiation and progression of oral cancer cells by increasing the expression of miR-9 that causes cancer cell arrest and apoptosis.
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of oral cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin inhibits oral squamous cell carcinoma SCC-9 cells proliferation by regulating miR-9 expression by Xiao C1, Wang L2, Zhu L2, Zhang C3, Zhou J. (PubMed)
(2) Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells by Khan AQ1, Siveen KS1, Prabhu KS1, Kuttikrishnan S1, Akhtar S1, Shaar A1, Raza A2, Mraiche F3, Dermime S2, Uddin S. (PubMed)
(3) Mouth (Oral) Cancer by Kyle J. Norton
Foods that reach the end of the esophagus enters the stomach through a muscular valve called the lower esophageal sphincter.
The stomach not only forms part of the digestive system, but it also is the first organ to digest foods.
Oral/ Stomach cancer is a group of cancer characterized by malignant cell growth in the tissue located in the oral cavity, including the tissue of the lips or the tongue, cheek lining, floor of the mouth, gums (gingiva) and the roof of the mouth (palate).
According to worldwide statistics, oral cancer is the 11th most common malignancy in the world. There is a global trend of a slight decrease in the incidence of oral cancer, except for tongue cancer.
In the US, 53,000 Americans will be diagnosed with oral or oropharyngeal cancer in 2019. Oral cancer also will cause the death of over 9,750 Americans.
Patients with oral cancer depending on the stage and grade may experience general symptoms shared by other types of cancer such as unintended weight loss of over 10%, loss of appetite, persistent fatigue and nausea and vomiting accompanied by
* Poorly healing mouth ulcer
Poorly healing mouth ulcer indicates something wrong within the cells and can be cancerous if left untreated for a prolonged period of time.
*A sore that does not heal on the lip or in the mouth
If the ulcer does not heal with 2 weeks, it may be a sign of abnormal cell growth or tumor.
* A lump or thickening in the oral cavity
Due to cell growth irregularity.
* Patches that are white or red (or both) inside the mouth or on the lips
Maybe due to infection or inflammation.
* Loose teeth
Maybe due to inflammation of gingivitis
*Dentures that not fit well
It increases the risk of infection and gum damage.
* Problems speaking clearly
* A lump in the neck
Cancer has spread to the lymph nodes in the neck region.
If you have some of the aforementioned symptoms, please check with your doctor to rule out the oral cancer possibility.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a potential ingredient for the treatment of oral cancer associated with squamous cells, researchers examined the effect of curcumin on oral squamous cell carcinoma (OSCC).
According to the tested differentiation, the expression levels of miR-9 were significantly lower in clinical OSCC specimens compared to non-tumor tissues.
Where miR-9 is a microRNA involved in cancer cell arrest and apoptosis.
Administration of curcumin inhibited OSCC cells (SCC-9 cells) proliferation by exhibiting the miR-9 expression and suppressing Wnt/β-catenin signaling associated with the promotion of cancer progression by regulating the tumor-immune cycle.
Additional analysis of the interaction of signaling pathways suggested that the mechanisms that regulate the gene expression such as GSK-3β, phosphorylated GSK-3β and β-catenin associated with the inhibition of Wnt/β-catenin signaling pathway were also increased by the application of curcumin.
Furthermore, Cyclin D1 involved in the promotion of cell cycle progression in the tested cell line was also decreased by curcumin injection.
In Micro RNA analysis, reduced expression of miR-9 by anti-miR-9 not only attenuated the growth-suppressive effects of curcumin on SCC-9 cells but also re-activated Wnt/β-catenin signaling that was inhibited by curcumin.
In other words, curcumin inhibited the initiation and progression of oral cancer cells by increasing the expression of miR-9 that causes cancer cell arrest and apoptosis.
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of oral cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin inhibits oral squamous cell carcinoma SCC-9 cells proliferation by regulating miR-9 expression by Xiao C1, Wang L2, Zhu L2, Zhang C3, Zhou J. (PubMed)
(2) Curcumin-Mediated Degradation of S-Phase Kinase Protein 2 Induces Cytotoxic Effects in Human Papillomavirus-Positive and Negative Squamous Carcinoma Cells by Khan AQ1, Siveen KS1, Prabhu KS1, Kuttikrishnan S1, Akhtar S1, Shaar A1, Raza A2, Mraiche F3, Dermime S2, Uddin S. (PubMed)
(3) Mouth (Oral) Cancer by Kyle J. Norton
Green tea, The Beverage Kills Bacterial Staphylococcus and Streptococcus That Cause Cellulitis
Green tea may have a therapeutic and positive effect on reducing the risk and treatment of cellulitis, some scientists suggested.
The results of the investigation were evaluated by numbers of respectable institutes, including the University of Indonesia and Mashhad University of Medical Sciences and published online in some medical literature databases including PubMed.
Cellulitis is a common and serious bacterial skin infection that affects the deep layer of skin, caused mostly by Staphylococcus and Streptococcus bacteria, inducing symptoms of a red, swollen skin rash (usually on the lower legs or arms) that feels tender and hot.
The skin infectious disease can appear anywhere in the body, however, in most cases, it affects the skin of the lower legs.
Some researchers suggested that people with a weakened immune system such as age population and intake of immune-suppressive drugs and obesity are most likely to develop cellulitis.
As always, most cases of cellulitis are treated with antibiotics in a period of 5-10 days. Please make sure that you discuss the side effects of the medicine with your doctor.
Although it is rare, some people with severe cellulitis that experience severe symptoms of high fever or vomiting and fail to respond to treatment.
Recurrences of cellulitis may require antibiotics that are given by IV.
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the searching of natural antibiotics against skin infection such as cellulitis, by reviewing some plants for the treatment of skin diseases taken place during the past 17 year using the of plants is as old as the mankind, researchers found that green tea with abundant polyphenols, epigallocatechin gallate exerts a strong effect as antioxidants to reduce the risk of skin diseases, including tumors, herpes, and cellulitis.
According to the National Center for Complementary and Alternative Medicine, the application of EGCG also demonstrated potential in rejuvenated old skin cells.
Further analysis of green tea catechins, the major green tea polyphenols, exhibited antimicrobial activity against resistant pathogens in induction of skin infection, including cellulitis, researchers at the Mashhad University of Medical Sciences conducted a study to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) values of different agents against bacterial strains, through assessing the interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin against standard and clinical isolates of Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
According to the final phase of the experiment, researchers indicated that
*The MICs of gentamicin against bacterial strains were in the range of 0.312 - 320 μg/mL and the MIC values of both types of catechins were 62.5 - 250 μg/ mL.
* Green tea extract showed insufficient antibacterial activity when used alone
* Methylxanthines had no intrinsic inhibitory activity against any of the bacterial strains tested.
* When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1).
* A combination of caffeine with gentamicin did not alter the MIC values of gentamicin.
The results of all comparisons after taking into account other co and confounders revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains", Dr. Fazly Bazzaz BS, the lead author said.
Moreover, the evaluate the antibacterial activity of the Indonesian water-soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa) also lends support of the above differentiation.
According to the University of Indonesia,
* The inhibition zone diameter of green tea extracts for S. aureus ATCC 25923 and MRSA were (18.970 ± 0.287) mm, and (19.130 ± 0.250) mm respectively.
* While the inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
* The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
* Finally, the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa was 800 µg/mL, and 800 µg/mL, respectively.
Taken together, green tea and its bioactive compounds may be considered as a functional food for reduced risk and treatment of cellulitis caused by Staphylococcus and Streptococcus bacterial infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plants used to treat skin diseases by Nahida Tabassum and Mariya Hamdani(PMC)
(2) Effect of Catechins, Green tea Extract, and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
The results of the investigation were evaluated by numbers of respectable institutes, including the University of Indonesia and Mashhad University of Medical Sciences and published online in some medical literature databases including PubMed.
Cellulitis is a common and serious bacterial skin infection that affects the deep layer of skin, caused mostly by Staphylococcus and Streptococcus bacteria, inducing symptoms of a red, swollen skin rash (usually on the lower legs or arms) that feels tender and hot.
The skin infectious disease can appear anywhere in the body, however, in most cases, it affects the skin of the lower legs.
Some researchers suggested that people with a weakened immune system such as age population and intake of immune-suppressive drugs and obesity are most likely to develop cellulitis.
As always, most cases of cellulitis are treated with antibiotics in a period of 5-10 days. Please make sure that you discuss the side effects of the medicine with your doctor.
Although it is rare, some people with severe cellulitis that experience severe symptoms of high fever or vomiting and fail to respond to treatment.
Recurrences of cellulitis may require antibiotics that are given by IV.
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the searching of natural antibiotics against skin infection such as cellulitis, by reviewing some plants for the treatment of skin diseases taken place during the past 17 year using the of plants is as old as the mankind, researchers found that green tea with abundant polyphenols, epigallocatechin gallate exerts a strong effect as antioxidants to reduce the risk of skin diseases, including tumors, herpes, and cellulitis.
According to the National Center for Complementary and Alternative Medicine, the application of EGCG also demonstrated potential in rejuvenated old skin cells.
Further analysis of green tea catechins, the major green tea polyphenols, exhibited antimicrobial activity against resistant pathogens in induction of skin infection, including cellulitis, researchers at the Mashhad University of Medical Sciences conducted a study to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) values of different agents against bacterial strains, through assessing the interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin against standard and clinical isolates of Staphylococcus aureus (S. aureus) and the standard strain of Pseudomonas aeruginosa (P. aeruginosa).
According to the final phase of the experiment, researchers indicated that
*The MICs of gentamicin against bacterial strains were in the range of 0.312 - 320 μg/mL and the MIC values of both types of catechins were 62.5 - 250 μg/ mL.
* Green tea extract showed insufficient antibacterial activity when used alone
* Methylxanthines had no intrinsic inhibitory activity against any of the bacterial strains tested.
* When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1).
* A combination of caffeine with gentamicin did not alter the MIC values of gentamicin.
The results of all comparisons after taking into account other co and confounders revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of S. aureus and standard P. aeruginosa strains", Dr. Fazly Bazzaz BS, the lead author said.
Moreover, the evaluate the antibacterial activity of the Indonesian water-soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus (S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa) also lends support of the above differentiation.
According to the University of Indonesia,
* The inhibition zone diameter of green tea extracts for S. aureus ATCC 25923 and MRSA were (18.970 ± 0.287) mm, and (19.130 ± 0.250) mm respectively.
* While the inhibition zone diameter for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were (17.550 ± 0.393) mm and (17.670 ± 0.398) mm respectively.
* The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 µg/mL and 400 µg/mL, respectively.
* Finally, the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa was 800 µg/mL, and 800 µg/mL, respectively.
Taken together, green tea and its bioactive compounds may be considered as a functional food for reduced risk and treatment of cellulitis caused by Staphylococcus and Streptococcus bacterial infection.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plants used to treat skin diseases by Nahida Tabassum and Mariya Hamdani(PMC)
(2) Effect of Catechins, Green tea Extract, and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria by Fazly Bazzaz BS1, Sarabandi S2, Khameneh B3, Hosseinzadeh H4.(PubMed)
(3) Antimicrobial activity of green tea extract against isolates of methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa by Radji M1, Agustama RA, Elya B, Tjampakasari CR.(PubMed)
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