Scientists may have found a natural whole food for the treatment of type II diabetes without inducing any side effects, some studies suggested,
Type II diabetes is a chronic acquired medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose.
The disease is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The exact cause of type II diabetes is unknown. However, some researchers suggested that the condition is most likely caused by genetic mutation and an unhealthy lifestyle.
Other risk factors associated with the early onset of type II diabetes include overweight or obese, age 45 or older, family history, ethnicity, Alaska Native, high blood pressure and cholesterol and women with polycystic ovary syndrome.
Dr. Waqas Sami, the lead author in the study "Effect of diet on type 2 diabetes mellitus: A review" wrote. "Dietary habits and sedentary lifestyle are the major factors for rapidly rising incidence of DM among developing countries. In type 2 diabetics, recently, the elevated HbA1c level has also been considered as one of the leading risk factors for developing microvascular and macrovascular complications" and "Improvement in the elevated HbA1c level can be achieved through diet management; thus, the patients could be prevented from developing the diabetes complications. Awareness about diabetes complications and consequent improvement in dietary knowledge, attitude, and practices lead to better control of the disease".
These results suggested changes in diet and lifestyle are the most effective method in the management of type II diabetes.
Medication including Alpha-glucosidase inhibitors. Thiazolidinediones (TZDs) Glucagonlike peptide–1 (GLP-1) agonists. Dipeptidyl peptidase IV (DPP-4) inhibitors used for the treatment of type II diabetes may be effective, however, they are to know to induce serious side effects such as low blood sugar, upset stomach, skin rash or itching, weight gain. kidney complications, upset stomach, tiredness or dizziness,... and metal taste.
If you are currently taking one of the above medicine, please make sure that you discuss the side effects with your doctor and know how to deal with them.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
Herbal medicine has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc..
The Chemical ingredients
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
In the study to examine the clinical effectiveness of aloe vera, a popular herbal remedy in the United Kingdom for the treatment of type II diabetes, researchers at the University of Exeter, launched a review by researching the database of MEDLINE, EMBASE, Biosis, and the Cochrane Library.
Only controlled clinical trials (on any indication) were included in the study.
There were no restrictions on the language of publication. All trials were read and data were extracted in a standardized, pre-defined manner.
After differentiating the 10 selected studies, researchers found that oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidemia.
However, the topical application of aloe vera was not an effective preventative for radiation-induced injuries.
Furthermore, Dr. Okyar A and colleagues, in clarifying the controversy over the past 15 years on the hypoglycemic activity of Aloe species, launched an investigation with separate experiments on three main groups of rats, namely, non-diabetic (ND), type I (IDDM) and type II (NIDDM) diabetic rats.
At the end of the experiment, researchers found that
* Application of Aloe vera A. vera leaf pulp and gel extracts were ineffective on lowering the blood sugar level of ND rats.
* A. vera leaf pulp extract showed hypoglycemic activity on IDDM and NIDDM rats, the effect being enhanced for type II diabetes in comparison with glibenclamide.
* On the contrary, A. vera leaf gel extract showed hyperglycaemic activity on NIDDM rats.
These results suggested, pulps of Aloe vera leaves devoid of the gel could be useful in the treatment of non-insulin dependent diabetes mellitus.
Taken all together Aloe Vera may be considered an adjunct therapy for treatment in patients non-insulin-dependent type 2 diabetes.
However, due to the limitation of the above studies, additional data collection large example size and multi-centers studies performed with human consumption of the whole food Aloe vera during the course of the disease will be necessary to complete the picture of Aloe vera anti-diabetes possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe vera: a systematic review of its clinical effectiveness. by Vogler BK, Ernst E.(PubMed)
(2) Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. by Kim K, Kim H, Kwon J, Lee S, Kong H, Im SA, Lee YH, Lee YR, Oh ST, Jo TH, Park YI, Lee CK, Kim K.(PubMed)
(3) Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models.
Okyar A, Can A, Akev N, Baktir G, Sütlüpinar N.(PubMed)
(4) Effect of diet on type 2 diabetes mellitus: A review by Waqas Sami,1,2 Tahir Ansari,3 Nadeem Shafique Butt,4 and Mohd Rashid Ab Hamid. (PubMed)
Thursday, October 31, 2019
Navy Bean Promotes the Expression of Metabolite Markers that Improve Colon Health
Metabolite markers are the reaction of the metabolites that respond sensitively to phytochemical exposure.
Phytochemicals are plant-based natural components that form an important part in the human diet and animal feed. Synthetic phytochemicals are also commonly found in dietary supplements and pharmacological agents.
Phytochemicals are chemical compound produced by the plants to protect them against predators such as insects and bacteria and fungi. Some phytochemicals are also used in traditional medicine to combat diseases.
According to Prof. Chi Chen in the investigation of the metabolite markers of phytochemicals wrote, "the bidirectional interactions between phytochemicals and the metabolic system, such as the disposition of phytochemicals, the regulation of nutrient, antioxidant, and microbial metabolism, and overdose-induced toxicities".
In other words, phytochemicals including bioactive phytochemical play an essential role in regulating the metabolic system through many metabolic pathways.
Believe it or not, metabolic effects have a strong impact on phytochemicals on the digestion, absorption, distribution, and metabolism of nutrients and antioxidants.
On the digestive system, bioactive phytochemicals play an essential role in the human diet as a valuable source of many bioactive components: phenolic compounds, vitamins or bioactive peptides.
On chronic diseases, consumption of total phytochemical intake has been found to reduce the risk of cardiovascular disease, cancer, and neurodegenerative diseases.
On the metabolism of nutrients, gene-phytochemical interactions are individual differences depending on the individual genetic proposition, including the capacity to influence disease risk via several complementary and overlapping mechanisms.
More precisely, a person genetic variation in pathways has a strong effect on absorption, metabolism, and distribution of phytochemicals that expose at the tissue level or alter the biological response.
On antioxidant perspective, although phytochemicals and antioxidants are different, phytochemical antioxidants capacity demonstrated potential effects on oxidative status, that decrease the risk proteins, lipids, and cellular damage.
Collectively, by looking at the forms of metabolite markers, the tested assays after exposing to phytochemicals, researchers may know the inaction of the phytochemical and metabolic system.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.
With an aim to find a natural compound for the promotion of gut health, researchers examined investigated metabolite markers of dry bean consumption in parallel human and mouse studies.
The study included 46 men who received dry bean enriched diet (250 g/day) for 4-weeks and 12 mice that received a standardized diet containing either 0 or 10% navy bean ethanol extract for 6 weeks.
According to the self-reported compared to the baseline, serum pipecolic acid (PA) and S-methyl cysteine (SMC) were elevated after dry bean consumption in human and mouse studies.
In other words, serum levels of pipecolic acid and S-methyl cysteine are metabolite markers that are useful to measure the amount of dry and navy bean consumption.
More precisely, according to the unpaired t-tests, a navy bean extract-enriched diet altered 26 metabolites (9% of analyzed metabolites) at P < 0.05 and 7 metabolites (2.4%) at q < 0.05 using unpaired t-tests; the most significant being PA, SMC, and NAO (all q < 0.003).
Furthermore, identified the biomarkers of dry (navy) bean intake may improve the understanding of the effect of navy bean in reducing the risk of colorectal cancer.
In intestinal microbial metabolism, the conversion of lysine to pipecolic acid (PA) may confer chemopreventive benefits for the human host because PA is a precursor of microbial compounds with anti-inflammatory property.
Taken altogether, the dry beans including navy bean may be considered a remedy for the improvement of colon health, through its metabolite markers, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies by Perera T1, Young MR, Zhang Z, Murphy G, Colburn NH, Lanza E, Hartman TJ, Cross AJ, Bobe G. (PubMed)
(2) Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors by Baxter BA1, Oppel RC2, Ryan EP. (PubMed)
(3) Metabolite Markers of Phytochemicals by Prof. Chi Chen (Metabolites)
Phytochemicals are plant-based natural components that form an important part in the human diet and animal feed. Synthetic phytochemicals are also commonly found in dietary supplements and pharmacological agents.
Phytochemicals are chemical compound produced by the plants to protect them against predators such as insects and bacteria and fungi. Some phytochemicals are also used in traditional medicine to combat diseases.
According to Prof. Chi Chen in the investigation of the metabolite markers of phytochemicals wrote, "the bidirectional interactions between phytochemicals and the metabolic system, such as the disposition of phytochemicals, the regulation of nutrient, antioxidant, and microbial metabolism, and overdose-induced toxicities".
In other words, phytochemicals including bioactive phytochemical play an essential role in regulating the metabolic system through many metabolic pathways.
Believe it or not, metabolic effects have a strong impact on phytochemicals on the digestion, absorption, distribution, and metabolism of nutrients and antioxidants.
On the digestive system, bioactive phytochemicals play an essential role in the human diet as a valuable source of many bioactive components: phenolic compounds, vitamins or bioactive peptides.
On chronic diseases, consumption of total phytochemical intake has been found to reduce the risk of cardiovascular disease, cancer, and neurodegenerative diseases.
On the metabolism of nutrients, gene-phytochemical interactions are individual differences depending on the individual genetic proposition, including the capacity to influence disease risk via several complementary and overlapping mechanisms.
More precisely, a person genetic variation in pathways has a strong effect on absorption, metabolism, and distribution of phytochemicals that expose at the tissue level or alter the biological response.
On antioxidant perspective, although phytochemicals and antioxidants are different, phytochemical antioxidants capacity demonstrated potential effects on oxidative status, that decrease the risk proteins, lipids, and cellular damage.
Collectively, by looking at the forms of metabolite markers, the tested assays after exposing to phytochemicals, researchers may know the inaction of the phytochemical and metabolic system.
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.
With an aim to find a natural compound for the promotion of gut health, researchers examined investigated metabolite markers of dry bean consumption in parallel human and mouse studies.
The study included 46 men who received dry bean enriched diet (250 g/day) for 4-weeks and 12 mice that received a standardized diet containing either 0 or 10% navy bean ethanol extract for 6 weeks.
According to the self-reported compared to the baseline, serum pipecolic acid (PA) and S-methyl cysteine (SMC) were elevated after dry bean consumption in human and mouse studies.
In other words, serum levels of pipecolic acid and S-methyl cysteine are metabolite markers that are useful to measure the amount of dry and navy bean consumption.
More precisely, according to the unpaired t-tests, a navy bean extract-enriched diet altered 26 metabolites (9% of analyzed metabolites) at P < 0.05 and 7 metabolites (2.4%) at q < 0.05 using unpaired t-tests; the most significant being PA, SMC, and NAO (all q < 0.003).
Furthermore, identified the biomarkers of dry (navy) bean intake may improve the understanding of the effect of navy bean in reducing the risk of colorectal cancer.
In intestinal microbial metabolism, the conversion of lysine to pipecolic acid (PA) may confer chemopreventive benefits for the human host because PA is a precursor of microbial compounds with anti-inflammatory property.
Taken altogether, the dry beans including navy bean may be considered a remedy for the improvement of colon health, through its metabolite markers, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies by Perera T1, Young MR, Zhang Z, Murphy G, Colburn NH, Lanza E, Hartman TJ, Cross AJ, Bobe G. (PubMed)
(2) Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors by Baxter BA1, Oppel RC2, Ryan EP. (PubMed)
(3) Metabolite Markers of Phytochemicals by Prof. Chi Chen (Metabolites)
Cranberry Arrests Breast Cancer Cells in Vitro
The women's breasts are made of tissues that produce milk (glandular tissue) and fat. The size of a woman's breast is totally depending on the amount of fat in the breast.
Cancer is a class of medical conditions associated with cell growth uncontrollably in the specific tissue of the gland and organ.
Breast cancer is a medical condition caused by cell growth irregularly due to the alternation of cell DNA that often begins in the cells on the surface of the inner lining of the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
At the advanced stage after colonizing the deeper layer tissues to form a tumor through proliferation, invasive cancer cells can travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
Most common secondary cancers spread by primary breast cancer are bone, liver, lung and brain cancer.
According to the statistics, in the US, approximately 268,600 new cases of invasive breast cancer will be diagnosed in 2019, along with 62,930 new cases of non-invasive (in situ) breast cancer.
The lifetime the risk of getting invasive breast cancer in the North America of a woman is 1/8.
The 5 years survival rate of breast cancer diagnosed in the localized stage is 100%.
The exact causes of breast cancer are not identified. Epidemiologically, aging, genetic proposition, female gender, family history, history of pregnancy, dense breast tissue and smoking are some of the most prevalent factors that are found patient with the disease.
However, some researchers in the investigated the risk of breast cancer in obese patients suggested that the promotion of a high-fat diet that causes the increased incidences of obesity in the US may have a strongly negative impact to induce the onset of breast cancer in women.
Dr. Manuel Picon‐Ruiz, the lead scientist wrote, "Recent decades have seen an unprecedented rise in obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than 1.9 billion adults were overweight (body mass index [BMI], 25‐29.9 kg/m2), and of these, over 600 million were obese (BMI ≥30 kg/m2)".
And, "Obesity is associated both with a higher risk of developing breast cancer, particularly in postmenopausal women and with worse disease outcome for women of all ages".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of cancer, researchers examined the effect of the efficacy of cranberry phytochemical extracts significantly inhibited human breast cancer MCF-7 cell.
According to the tested differentiation, at doses of 5 to 30mg/mL, cranberry phytochemical extracts induced apoptosis in MCF-7 cells in a dose-dependent manner, after exposure for 4h.
Compared to the control group, cranberry phytochemical extracts at a dose of 50mg/mL exhibited an additional 25% higher ratio of apoptotic cells to total cells.
Furthermore, at doses from 10 to 50mg/mL cranberry phytochemical extracts exerted significantly arrested MCF-7 cells at G0/G1 phase.
Moreover, A constant increasing pattern of the G1/S index was observed in the cranberry extract treatment group compared to the decrease of G1/S ratio of the control group between 10 and 24h treatment.
Additionally, according to the cell cycle division analysis, cranberry extracts induced cell cycle arrest in the G1/S in MCF-7 cells was approximately 6 times higher than that of the control group.
Based on the findings, researchers after taking other factors into account said," These results suggest that cranberry phytochemical extracts possess the ability to suppress the proliferation of human breast cancer MCF-7 cells and this suppression is at least partly attributed to both the initiation of apoptosis and the G1 phase arrest".
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of breast cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells by Sun J1, Hai Liu R. (PubMed)
(2) Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention by Manuel Picon‐Ruiz, PhD, 1 Cynthia Morata‐Tarifa, PhD, 2 Janeiro J. Valle‐Goffin, MD, 3Eitan R. Friedman, MD, 4 and Joyce M. Slingerland, MD, PhD. (PMC)
Cancer is a class of medical conditions associated with cell growth uncontrollably in the specific tissue of the gland and organ.
Breast cancer is a medical condition caused by cell growth irregularly due to the alternation of cell DNA that often begins in the cells on the surface of the inner lining of the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
At the advanced stage after colonizing the deeper layer tissues to form a tumor through proliferation, invasive cancer cells can travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.
Most common secondary cancers spread by primary breast cancer are bone, liver, lung and brain cancer.
According to the statistics, in the US, approximately 268,600 new cases of invasive breast cancer will be diagnosed in 2019, along with 62,930 new cases of non-invasive (in situ) breast cancer.
The lifetime the risk of getting invasive breast cancer in the North America of a woman is 1/8.
The 5 years survival rate of breast cancer diagnosed in the localized stage is 100%.
The exact causes of breast cancer are not identified. Epidemiologically, aging, genetic proposition, female gender, family history, history of pregnancy, dense breast tissue and smoking are some of the most prevalent factors that are found patient with the disease.
However, some researchers in the investigated the risk of breast cancer in obese patients suggested that the promotion of a high-fat diet that causes the increased incidences of obesity in the US may have a strongly negative impact to induce the onset of breast cancer in women.
Dr. Manuel Picon‐Ruiz, the lead scientist wrote, "Recent decades have seen an unprecedented rise in obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than 1.9 billion adults were overweight (body mass index [BMI], 25‐29.9 kg/m2), and of these, over 600 million were obese (BMI ≥30 kg/m2)".
And, "Obesity is associated both with a higher risk of developing breast cancer, particularly in postmenopausal women and with worse disease outcome for women of all ages".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of cancer, researchers examined the effect of the efficacy of cranberry phytochemical extracts significantly inhibited human breast cancer MCF-7 cell.
According to the tested differentiation, at doses of 5 to 30mg/mL, cranberry phytochemical extracts induced apoptosis in MCF-7 cells in a dose-dependent manner, after exposure for 4h.
Compared to the control group, cranberry phytochemical extracts at a dose of 50mg/mL exhibited an additional 25% higher ratio of apoptotic cells to total cells.
Furthermore, at doses from 10 to 50mg/mL cranberry phytochemical extracts exerted significantly arrested MCF-7 cells at G0/G1 phase.
Moreover, A constant increasing pattern of the G1/S index was observed in the cranberry extract treatment group compared to the decrease of G1/S ratio of the control group between 10 and 24h treatment.
Additionally, according to the cell cycle division analysis, cranberry extracts induced cell cycle arrest in the G1/S in MCF-7 cells was approximately 6 times higher than that of the control group.
Based on the findings, researchers after taking other factors into account said," These results suggest that cranberry phytochemical extracts possess the ability to suppress the proliferation of human breast cancer MCF-7 cells and this suppression is at least partly attributed to both the initiation of apoptosis and the G1 phase arrest".
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of breast cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells by Sun J1, Hai Liu R. (PubMed)
(2) Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention by Manuel Picon‐Ruiz, PhD, 1 Cynthia Morata‐Tarifa, PhD, 2 Janeiro J. Valle‐Goffin, MD, 3Eitan R. Friedman, MD, 4 and Joyce M. Slingerland, MD, PhD. (PMC)
Beware of Drug Interaction of Green tea and Green Tea Extract, Scientists Warn
Green may have processed a drug interaction property that inhibits the effect of conventional medicine, some scientists suggested.
Drug interactions are the greatest concern of some scientists, particularly in the pharmaceutical community as these effects can potentially reduce the desired effects for the treatment of certain diseases.
Intake of some drugs together, can reduce the absorption or increase the metabolism or elimination of other drugs treatment potential.
Some drugs interaction can cause an allergic reaction from skin rash and itching to a life-threatening anaphylactic reaction.
If you are taking some drugs for the treatment of certain diseases, please make sure that you know some may interact with the others.
The Havard health in the article "7 things you can do to avoid drug interactions"(4) suggested that you
1. Know why you are taking each medication
2. Know how to take the drug
3. Fill all your prescriptions at the same pharmacy
4. Are suspicious of supplements
5. Go easy on grapefruit juice
6. Limit intake of alcohol
7. Talk to your pharmacist
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the review the summarizes published in vitro, animal, and clinical studies investigating the effects of green tea (Camellia sinensis) extract and associated catechins on drug-metabolizing enzymes and drug transporters, researchers at the Prince Sattam Bin Abdulaziz University, Al-Kharj suggested that
* Green tea extract and its main catechin, (-)-epigallocatechin-3-gallate, to varying degrees, inhibit the activity of the cytochrome P450 superfamily of enzymes of CYP1A1, CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2D6, and CYP3A4. UGT1A1 and UGT1A4 but not the major cytochrome P450 enzyme, in vitro
Where cytochrome P450 enzymes have a unique function in metabolizing potentially toxic compounds, including drugs and products of endogenous metabolism.
* A clinical study, the organic anion transporting polypeptide 1A1 transporter with the potential role of liver transporters and bile acids is also inhibited by (-)-epigallocatechin-3-gallate while P-glycoprotein, the multidrug resistance protein 1 (MDR1) is unaffected
These results suggested that patients should be cautious that the consumption of significant amounts of green tea beverages or green tea extract may interact with the substrates of organic anion transporting polypeptide as mentioned above.
Further to investigate the effects of green tea extract (GTE) and (-)-epigallocatechin-3-gallate (EGCG) on the pharmacokinetics of a non-selective hydrophilic β-blocker nadolol, which is reported to be a substrate for several drug transporters and is not metabolized by cytochrome P450 enzymes launched a study o the. male Sprague-Dawley rats.
The tested animals were given GTE (400 mg/kg), EGCG (150 mg/kg) or saline (control) by oral gavage, 30 min before a single intragastric administration of 10 mg/kg nadolol.
At the end of the experiment, researchers showed that
* Pretreatment with GTE resulted in marked reductions in the maximum concentration (Cmax) and area under the time-plasma concentration curve (AUC) of nadolol by 85% and 74%, respectively, compared with control.
* EGCG alone significantly reduced Cmax and AUC of nadolol.
* The amounts of nadolol excreted into the urine were decreased by pretreatments with GTE and EGCG, while the terminal half-life of nadolol was not different among groups.
These results suggest that the coadministration with green tea catechins, particularly EGCG, causes a significant alteration in the pharmacokinetics of nadolol, possibly through the inhibition of its intestinal absorption mediated by uptake transporters.
Taken all together, green tea, green tea extract (GTE) and (-)-epigallocatechin-3-gallate (EGCG) can interact with the drug-metabolizing enzymes and drug transporters including nadolol.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats by Misaka S1, Miyazaki N, Fukushima T, Yamada S, Kimura J.(PubMed)
(2) An Appraisal of Drug-Drug Interactions with Green Tea Albassam AA1, Markowitz JS2.(PubMed)
(3) Effects of green tea extract on the pharmacokinetics of quetiapine in rats by Ezzeldin E1, Asiri YA2, Iqbal M1. (PubMed)
(4) 7 things you can do to avoid drug interactions by Harvard Health
Drug interactions are the greatest concern of some scientists, particularly in the pharmaceutical community as these effects can potentially reduce the desired effects for the treatment of certain diseases.
Intake of some drugs together, can reduce the absorption or increase the metabolism or elimination of other drugs treatment potential.
Some drugs interaction can cause an allergic reaction from skin rash and itching to a life-threatening anaphylactic reaction.
If you are taking some drugs for the treatment of certain diseases, please make sure that you know some may interact with the others.
The Havard health in the article "7 things you can do to avoid drug interactions"(4) suggested that you
1. Know why you are taking each medication
2. Know how to take the drug
3. Fill all your prescriptions at the same pharmacy
4. Are suspicious of supplements
5. Go easy on grapefruit juice
6. Limit intake of alcohol
7. Talk to your pharmacist
Green tea is a precious drink processed number of health benefits known to almost everyone in Asia and the Western world.
In the review the summarizes published in vitro, animal, and clinical studies investigating the effects of green tea (Camellia sinensis) extract and associated catechins on drug-metabolizing enzymes and drug transporters, researchers at the Prince Sattam Bin Abdulaziz University, Al-Kharj suggested that
* Green tea extract and its main catechin, (-)-epigallocatechin-3-gallate, to varying degrees, inhibit the activity of the cytochrome P450 superfamily of enzymes of CYP1A1, CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2D6, and CYP3A4. UGT1A1 and UGT1A4 but not the major cytochrome P450 enzyme, in vitro
Where cytochrome P450 enzymes have a unique function in metabolizing potentially toxic compounds, including drugs and products of endogenous metabolism.
* A clinical study, the organic anion transporting polypeptide 1A1 transporter with the potential role of liver transporters and bile acids is also inhibited by (-)-epigallocatechin-3-gallate while P-glycoprotein, the multidrug resistance protein 1 (MDR1) is unaffected
These results suggested that patients should be cautious that the consumption of significant amounts of green tea beverages or green tea extract may interact with the substrates of organic anion transporting polypeptide as mentioned above.
Further to investigate the effects of green tea extract (GTE) and (-)-epigallocatechin-3-gallate (EGCG) on the pharmacokinetics of a non-selective hydrophilic β-blocker nadolol, which is reported to be a substrate for several drug transporters and is not metabolized by cytochrome P450 enzymes launched a study o the. male Sprague-Dawley rats.
The tested animals were given GTE (400 mg/kg), EGCG (150 mg/kg) or saline (control) by oral gavage, 30 min before a single intragastric administration of 10 mg/kg nadolol.
At the end of the experiment, researchers showed that
* Pretreatment with GTE resulted in marked reductions in the maximum concentration (Cmax) and area under the time-plasma concentration curve (AUC) of nadolol by 85% and 74%, respectively, compared with control.
* EGCG alone significantly reduced Cmax and AUC of nadolol.
* The amounts of nadolol excreted into the urine were decreased by pretreatments with GTE and EGCG, while the terminal half-life of nadolol was not different among groups.
These results suggest that the coadministration with green tea catechins, particularly EGCG, causes a significant alteration in the pharmacokinetics of nadolol, possibly through the inhibition of its intestinal absorption mediated by uptake transporters.
Taken all together, green tea, green tea extract (GTE) and (-)-epigallocatechin-3-gallate (EGCG) can interact with the drug-metabolizing enzymes and drug transporters including nadolol.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats by Misaka S1, Miyazaki N, Fukushima T, Yamada S, Kimura J.(PubMed)
(2) An Appraisal of Drug-Drug Interactions with Green Tea Albassam AA1, Markowitz JS2.(PubMed)
(3) Effects of green tea extract on the pharmacokinetics of quetiapine in rats by Ezzeldin E1, Asiri YA2, Iqbal M1. (PubMed)
(4) 7 things you can do to avoid drug interactions by Harvard Health
Herbal Andrographis, the Natural Liver Protective Functional Remedy, Studies Found
Scientists may have found a herbal medicine which processes strong liver-protective effects, some studies suggested.
The hepatoprotective effect is the action of the prevention of the liver against liver damage or toxicity.
There is no single cause of liver diseases. Researchers suggested that virus such as hepatitis A, B, C, long-term excessive alcohol drinking and genetic mutation inherited from the parents is the major risk factors associated with the early onset of the diseases.
Some researchers suggested overweight and obesity and congenital diseases such as Hemochromatosis and Wilson’s disease also are the prevalent risk factors of liver damage and diseases.
Liver damage and disease can also be caused by long-term intake of certain medications, such as paracetamol and Illegal drugs such as cocaine.
In the article on liver diseases, the 24 health also include autoimmune diseases that cause inflammation to the liver.
Sadly, according to the statistic, the mortality rate infected by viral hepatitis have increased by 63% from 890,000 in 1990 to 1.45 million in 2013, according to a review of data collected in 183 countries.
Symptoms of liver diseases include persistent jaundice and gastrointestinal discomforts, abdominal pain, and swelling, leg and ankles swelling, itching, and pale color of stool.
Please check with your doctor to rule out the liver disease and damage possibility, if you are experiencing some of the above symptoms.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The herb has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
The Ingredients
Besides the main ingredient andrographolides, giving the plant a bitter taste, other ingredients include diterpene lactones, such as neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoids viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
As of today, despite enormous advances in modern medicine, conventional medicine can only focus to reduce symptoms of liver diseases. There is no completely effective medicine that can stimulate hepatic function, or offer complete protection of the organ, or help to regenerate hepatic cells.
In the finding of a natural hepatoprotective agent that can help to relieve the pressure of conventional medicine in patients with liver damage or diseases, researchers at the Vinayaka Missions University conducted a study to evaluate the liver protective activity of herbal Andrographis in liver injury in rats.
After subcutaneous injection of 50% v/v carbon tetrachloride in liquid paraffin at a dose of 3 mL/kg on alternate days for a period of 4 weeks to induce chronic liver damage, the Male Wistar rats were treated with methanol and aqueous extracts of herbal Andrographis orally at a dose of 845 mg/kg/day.
At the end of the experiment, researchers found that* Herbal Andrographis extracts demonstrate clinically significant activity in comparison to a standard drug.
* Hepatic steatosis, hydropic degeneration and necrosis caused by the injection of the carbon tetrachloride were completely disappeared in the standard and extract-treated groups.
Further analysis also discovered, herbal Andrographis extracts exhibited hepatoprotective action against carbon tetrachloride-induced liver injury.
Dr. Sangameswaran B, the lead author at the final report wrote, "The present investigation established pharmacological evidence to support the folklore claim that it is used traditionally as a hepatoprotective agent".
Additional investigation of the liver protective effect of Andrographolide (AN), a major bioactive compound isolated from herbal Andrographis, researchers at the Dr. Hari Singh Gour Central University, formulate AN herbosomes (ANH) through complexation with naturally occurring soya-phosphatidylcholine (SPC) for enhancing absorption with carbon tetrachloride inducing hepatotoxicity rat model and compared.
The ANH showed a significant liver protective effect compared to the standard drug (Silymarin).
Application of ANH in an animal model has better bioavailability than those of AN observed by the statistics in vitro absorption and hence improved hepatoprotection as compared to plain AN at an equivalent dose.
Taken all together, herbal Andrographis and its bioactive ingredient Andrographolide (AN)may be considered an adjunct therapy in aiding the conventional medicine in providing the extra protection of the liver and treatment of liver damage and diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats.
Tatiya AU, Surana SJ, Sutar MP, Gamit NH. (PubMed)
(2) Hepatoprotective effect of leaf extracts of Andrographis lineata nees on liver damage caused by carbon tetrachloride in rats. by Sangameswaran B, Reddy TC, Jayakar B.(PubMed)
(3) Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-andrographolide vesicular system. by Jain PK, Khurana N, Pounikar Y, Gajbhiye A, Kharya MD. (PubMed)
The hepatoprotective effect is the action of the prevention of the liver against liver damage or toxicity.
There is no single cause of liver diseases. Researchers suggested that virus such as hepatitis A, B, C, long-term excessive alcohol drinking and genetic mutation inherited from the parents is the major risk factors associated with the early onset of the diseases.
Some researchers suggested overweight and obesity and congenital diseases such as Hemochromatosis and Wilson’s disease also are the prevalent risk factors of liver damage and diseases.
Liver damage and disease can also be caused by long-term intake of certain medications, such as paracetamol and Illegal drugs such as cocaine.
In the article on liver diseases, the 24 health also include autoimmune diseases that cause inflammation to the liver.
Sadly, according to the statistic, the mortality rate infected by viral hepatitis have increased by 63% from 890,000 in 1990 to 1.45 million in 2013, according to a review of data collected in 183 countries.
Symptoms of liver diseases include persistent jaundice and gastrointestinal discomforts, abdominal pain, and swelling, leg and ankles swelling, itching, and pale color of stool.
Please check with your doctor to rule out the liver disease and damage possibility, if you are experiencing some of the above symptoms.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The herb has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
The Ingredients
Besides the main ingredient andrographolides, giving the plant a bitter taste, other ingredients include diterpene lactones, such as neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoids viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
As of today, despite enormous advances in modern medicine, conventional medicine can only focus to reduce symptoms of liver diseases. There is no completely effective medicine that can stimulate hepatic function, or offer complete protection of the organ, or help to regenerate hepatic cells.
In the finding of a natural hepatoprotective agent that can help to relieve the pressure of conventional medicine in patients with liver damage or diseases, researchers at the Vinayaka Missions University conducted a study to evaluate the liver protective activity of herbal Andrographis in liver injury in rats.
After subcutaneous injection of 50% v/v carbon tetrachloride in liquid paraffin at a dose of 3 mL/kg on alternate days for a period of 4 weeks to induce chronic liver damage, the Male Wistar rats were treated with methanol and aqueous extracts of herbal Andrographis orally at a dose of 845 mg/kg/day.
At the end of the experiment, researchers found that* Herbal Andrographis extracts demonstrate clinically significant activity in comparison to a standard drug.
* Hepatic steatosis, hydropic degeneration and necrosis caused by the injection of the carbon tetrachloride were completely disappeared in the standard and extract-treated groups.
Further analysis also discovered, herbal Andrographis extracts exhibited hepatoprotective action against carbon tetrachloride-induced liver injury.
Dr. Sangameswaran B, the lead author at the final report wrote, "The present investigation established pharmacological evidence to support the folklore claim that it is used traditionally as a hepatoprotective agent".
Additional investigation of the liver protective effect of Andrographolide (AN), a major bioactive compound isolated from herbal Andrographis, researchers at the Dr. Hari Singh Gour Central University, formulate AN herbosomes (ANH) through complexation with naturally occurring soya-phosphatidylcholine (SPC) for enhancing absorption with carbon tetrachloride inducing hepatotoxicity rat model and compared.
The ANH showed a significant liver protective effect compared to the standard drug (Silymarin).
Application of ANH in an animal model has better bioavailability than those of AN observed by the statistics in vitro absorption and hence improved hepatoprotection as compared to plain AN at an equivalent dose.
Taken all together, herbal Andrographis and its bioactive ingredient Andrographolide (AN)may be considered an adjunct therapy in aiding the conventional medicine in providing the extra protection of the liver and treatment of liver damage and diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats.
Tatiya AU, Surana SJ, Sutar MP, Gamit NH. (PubMed)
(2) Hepatoprotective effect of leaf extracts of Andrographis lineata nees on liver damage caused by carbon tetrachloride in rats. by Sangameswaran B, Reddy TC, Jayakar B.(PubMed)
(3) Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-andrographolide vesicular system. by Jain PK, Khurana N, Pounikar Y, Gajbhiye A, Kharya MD. (PubMed)
Wednesday, October 30, 2019
Alfalfa, The Functional Herb Which Protects Our Body Against Type 2 Diabetes, Researchers Reveal
Diabetes is a chronic condition characterized by insufficient insulin entering the bloodstream to regulate glucose as a result of either cell in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes may also be caused by allergic reactions of cells in the immune system.
The actual causes of diabetes inflammatory conditions are debatable.
Some researchers also do not know why some people without genetic mutations are susceptible to type 2 diabetes while others do not.
However, certain risk factors such as for overweight and obesity (overexpression of fatty tissue that causes insulin resistant), physical inactivity, family history, race,,,,, and age. ...
Women developed gestational diabetes, polycystic ovary syndrome,.... and high blood pressure is also some major risk factors associated to increase the risk of type 2 diabetes.
The first line medicine used for the treatment of type 2 diabetes is metformin which processes a significant effect in improving the body tissue sensitivity to insulin. In other words, metformin improves the body uses insulin more effectively. and lowers glucose production in the liver.
In stage prediabetes, patients may not experience any symptoms. However, untreated diabetes or diabetes that do not manage properly, may increase the risk of cataracts and glaucoma, foot damage.
In the advance stage, untreated diabetes can also cause nerve damage or poor blood flow to the feet which in turn, increases the risk of various foot complications.
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding.
The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance the digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North America aboriginal has used Alfalfa seed as food, such as making bread and mush.
Ingredients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
It chemical constituents include flavones, isoflavones, sterols, Bichanin, Coumestrol, Diadzein, Formonetin, Genistein,.... and coumarin derivatives.
In the study to examine the Lucerne (alfalfa) effect by oral administrated the herbal extract through diet (62.5 g/kg) and drinking water (2.5 g/l) in reducing the hyperglycemia of streptozotocin-diabetic mice, researchers found
* Application of aqueous extract of lucerne exerts a significant stimulation of insulin secretion from the pancreatic B-cell line.
* Application of aqueous extract of lucern also promotes insulin-like activity in inhibited overexpression glucose.
* The sequential extraction with solvents revealed .higher insulin-releasing activity in both methanol and water fractions compared to one extract constituent.
Further analysis also suggested that the activity of the extract was found to be heat stable and enhanced by exposure to acid and alkali (0.1 M-HCl and NaOH).
Dr. Gray AM, the lead author at the final report wrote, "The results demonstrate the presence of antihyperglycaemic, insulin-releasing and insulin-like activity in the traditional antidiabetic plant, Medicago sativa".
Additionally, in the study to reaffirm the effect herbal alfalfa against onset of diabetes researchers launched a study to compare alfalfa with other herbal medicine including dried leaves of agrimony (Agrimonia eupatoria), blackberry (Rubus fructicosus), celandine (Chelidonium majus), eucalyptus (Eucalyptus globulus), lady's mantle (Alchemilla vulgaris), and lily of the valley (Convallaria majalis); seeds of coriander (Coriandrum sativum); dried berries of juniper (Juniperus communis); bulbs of garlic (Allium sativum) and roots of liquorice (Glycyrhizza glabra).
In mice administrated by streptozotocin (200 mg/kg i.p.) to induce the development of hyperphagia, polydipsia, bodyweight loss, hyperglycemia, and hypoinsulinemia, researchers found that
* Herbal alfalfa exerts a strong effect in reduced the level of hyperglycemia during the development of streptozotocin diabetes compared to other herbs.
* Herbal alfalfa reduced polydipsia and a reduced rate of body weight loss.
* Alfalfa initially countered the hyperinsulinaemic effect of streptozotocin, without affecting the fall in plasma insulin.
Dr. said, after taking into account of other co and confounders, " The results suggest that certain traditional plant treatments for diabetes, namely alfalfa,.......can retard the development of streptozotocin diabetes in mice".
Taking all together, herbal alfalfa may be considered a functional herb for the prevention and treatment of type 2 diabetes.
However, additional data collection on large example size and multi-center clinical studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of alfalfa anti-type 2 diabetes possibilities.
And long-term multiple dietary supplement consumption of a broad array of vitamin/mineral, herbal, and condition-specific dietary supplements on a daily basis should consult with their doctors or related field specialist before applying.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM, Flatt PR. (PubMed)
(2) Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. (PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)
In some cases, diabetes may also be caused by allergic reactions of cells in the immune system.
The actual causes of diabetes inflammatory conditions are debatable.
Some researchers also do not know why some people without genetic mutations are susceptible to type 2 diabetes while others do not.
However, certain risk factors such as for overweight and obesity (overexpression of fatty tissue that causes insulin resistant), physical inactivity, family history, race,,,,, and age. ...
Women developed gestational diabetes, polycystic ovary syndrome,.... and high blood pressure is also some major risk factors associated to increase the risk of type 2 diabetes.
The first line medicine used for the treatment of type 2 diabetes is metformin which processes a significant effect in improving the body tissue sensitivity to insulin. In other words, metformin improves the body uses insulin more effectively. and lowers glucose production in the liver.
In stage prediabetes, patients may not experience any symptoms. However, untreated diabetes or diabetes that do not manage properly, may increase the risk of cataracts and glaucoma, foot damage.
In the advance stage, untreated diabetes can also cause nerve damage or poor blood flow to the feet which in turn, increases the risk of various foot complications.
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding.
The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance the digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North America aboriginal has used Alfalfa seed as food, such as making bread and mush.
Ingredients
1. Essential amino acids
2. Calcium
3. Magnesium
4. Potassium
5. Iron
6. Phosphorus
7. Zinc
8. Beta carotene
9. vitamin C
10. vitamins D
11.Vitamin E
12. Vitamin K
It chemical constituents include flavones, isoflavones, sterols, Bichanin, Coumestrol, Diadzein, Formonetin, Genistein,.... and coumarin derivatives.
In the study to examine the Lucerne (alfalfa) effect by oral administrated the herbal extract through diet (62.5 g/kg) and drinking water (2.5 g/l) in reducing the hyperglycemia of streptozotocin-diabetic mice, researchers found
* Application of aqueous extract of lucerne exerts a significant stimulation of insulin secretion from the pancreatic B-cell line.
* Application of aqueous extract of lucern also promotes insulin-like activity in inhibited overexpression glucose.
* The sequential extraction with solvents revealed .higher insulin-releasing activity in both methanol and water fractions compared to one extract constituent.
Further analysis also suggested that the activity of the extract was found to be heat stable and enhanced by exposure to acid and alkali (0.1 M-HCl and NaOH).
Dr. Gray AM, the lead author at the final report wrote, "The results demonstrate the presence of antihyperglycaemic, insulin-releasing and insulin-like activity in the traditional antidiabetic plant, Medicago sativa".
Additionally, in the study to reaffirm the effect herbal alfalfa against onset of diabetes researchers launched a study to compare alfalfa with other herbal medicine including dried leaves of agrimony (Agrimonia eupatoria), blackberry (Rubus fructicosus), celandine (Chelidonium majus), eucalyptus (Eucalyptus globulus), lady's mantle (Alchemilla vulgaris), and lily of the valley (Convallaria majalis); seeds of coriander (Coriandrum sativum); dried berries of juniper (Juniperus communis); bulbs of garlic (Allium sativum) and roots of liquorice (Glycyrhizza glabra).
In mice administrated by streptozotocin (200 mg/kg i.p.) to induce the development of hyperphagia, polydipsia, bodyweight loss, hyperglycemia, and hypoinsulinemia, researchers found that
* Herbal alfalfa exerts a strong effect in reduced the level of hyperglycemia during the development of streptozotocin diabetes compared to other herbs.
* Herbal alfalfa reduced polydipsia and a reduced rate of body weight loss.
* Alfalfa initially countered the hyperinsulinaemic effect of streptozotocin, without affecting the fall in plasma insulin.
Dr. said, after taking into account of other co and confounders, " The results suggest that certain traditional plant treatments for diabetes, namely alfalfa,.......can retard the development of streptozotocin diabetes in mice".
Taking all together, herbal alfalfa may be considered a functional herb for the prevention and treatment of type 2 diabetes.
However, additional data collection on large example size and multi-center clinical studies performed with human consumption of the whole food during the course of the disease will be necessary to complete the picture of alfalfa anti-type 2 diabetes possibilities.
And long-term multiple dietary supplement consumption of a broad array of vitamin/mineral, herbal, and condition-specific dietary supplements on a daily basis should consult with their doctors or related field specialist before applying.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne) by Gray AM, Flatt PR. (PubMed)
(2) Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. (PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)
Herbal Aloe vera on Acne Vulgaris
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.
There are many types of skin diseases in this world, the most common one is acne. Most people know acne is caused by dirt in oily skin pores, but little is known that acne is also caused by the system of toxins in the body. If our liver and kidney can not cleanse all toxins in the body, then our skin becomes the third source for cleansing the remainder of toxins.
The Ingredients
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
The benefits
Acne vulgaris, one of the skin diseases with areas of scaly red skin with seborrhea, blackheads, and whiteheads. Aloe vera one of many herbs has been studied and researched in the pharmaceutical world, because of its common problem to the young ages and commercial profits. The study to compare the efficacy and safety of the combination of tretinoin (TR) cream (0.05%) and Aloe vera topical gel (50%) with TR and vehicle, has been well-tolerated and significantly more effective than TR and vehicle for the treatment of mild to moderate acne vulgaris and with less side effects. Other researchers in the observation of traditional medicines of many cultures used to treat skin diseases, indicated that certain ingredients, including aloe vera, have been identified in the treatment of psoriasis and atopic dermatitis,
The Side effects
1. Hepatitis
Some researchers concerned that the overuse of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause rheumatoid arthritis symptoms as a result of collagen in the plant
5. Etc.
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. by Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A.(PubMed)
(4) Innovations in natural ingredients and their use in skin care. by Fowler JF Jr, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)
(5) Oral aloe vera-induced hepatitis(PubMed)
(6) Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study(PubMed)
There are many types of skin diseases in this world, the most common one is acne. Most people know acne is caused by dirt in oily skin pores, but little is known that acne is also caused by the system of toxins in the body. If our liver and kidney can not cleanse all toxins in the body, then our skin becomes the third source for cleansing the remainder of toxins.
The Ingredients
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
The benefits
Acne vulgaris, one of the skin diseases with areas of scaly red skin with seborrhea, blackheads, and whiteheads. Aloe vera one of many herbs has been studied and researched in the pharmaceutical world, because of its common problem to the young ages and commercial profits. The study to compare the efficacy and safety of the combination of tretinoin (TR) cream (0.05%) and Aloe vera topical gel (50%) with TR and vehicle, has been well-tolerated and significantly more effective than TR and vehicle for the treatment of mild to moderate acne vulgaris and with less side effects. Other researchers in the observation of traditional medicines of many cultures used to treat skin diseases, indicated that certain ingredients, including aloe vera, have been identified in the treatment of psoriasis and atopic dermatitis,
The Side effects
1. Hepatitis
Some researchers concerned that the overuse of oral aloe vera may contribute to acute hepatitis, according to the study of "Oral aloe vera-induced hepatitis" by Bottenberg MM, Wall GC, Harvey RL, Habib S., posted in PubMed
2. Diarrhea, caused by the laxative effect of oral use of Aloe Vera
3. oral use of Aloe Vera may cause abdominal cramps and pain
4. It may cause rheumatoid arthritis symptoms as a result of collagen in the plant
5. Etc.
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References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. by Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A.(PubMed)
(4) Innovations in natural ingredients and their use in skin care. by Fowler JF Jr, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)
(5) Oral aloe vera-induced hepatitis(PubMed)
(6) Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study(PubMed)
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