Herbal Arnica may be used as a natural painkiller in alleviating pain with inducing any side effects, some scientists suggested.
Pain a natural response from the brain caused by intense or damaging stimuli with an aim to protect our body against injury or damage.
Pain can vary greatly such as mild, sharp, severe, and dull. Acute pain is the sensation that lasts for a short period of time.
Chronic pain is pain that lasts longer than 12 weeks. Most cases of chronic pain arising from an initial injury such as back injury or diseases such as rheumatoid arthritis, osteoarthritis, and fibromyalgia.
There are different types of pain, including
* Nociceptive pain is a normal response to injury of tissues such as skin, muscles, visceral organs, joints, tendons, or bones.
* Neuropathic pain is a type of pain caused by a primary lesion in the somatosensory nervous system
and
* Inflammatory pain is associated with the production of proinflammatory cytokines in response to the acute phase of infection and chronic inflammatory diseases.
Conventional medicine used for the treatment of pain are effective in improving the quality of life of patients. However, long-term use has been known to induce some common fatigue, mental cloudiness, unclear thinking, and mood change and serious cardiovascular issues, sexual dysfunction, side effects
Most common prescription painkillers are the nonsteroidal anti-inflammatory drug (NSAID) and
Opioids
Therefore, if you currently taking medication to reduce chronic pain, please make sure you know all the side effects
Arnica is a herbaceous species, genus perennial, belonging to the family Asteraceae, native to Europe and Asia.
The plant has been used in herbal medicine for centuries to treat strains, sprains, and bruises.
Colon Cancer is defined as a condition of the abnormal proliferation of cells in the colon.
Pain is a feeling triggered in the nervous system as a result of often caused by intense or damaging stimuli.
Besides containing contain helenalin as it main ingredient used as an anti-inflammatory agent in herbal medicine, the herbal plant also contains 11,13- dihydrohelenaline, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin.
In the finding, the natural topical compound for the treatment revelation of pain and a replacement of conventional a painkiller with little or no side effects, researchers at the Department of Plastic Surgery of Queen Victoria Hospital in West Sussex, examine the herb Arnica montana, in topical formulations used in the traditional medicine for pain relief.
Thirty-seven patients undergoing bilateral endoscopic carpal-tunnel released between June 1998 and January 2000 were included in a double-blind, randomized comparison of Arnica administration versus placebo.
Grip strength, waist circumference, and perceived pain measured 1 and 2 weeks after surgery. The application of Arnica showed no difference in grip strength or wrist circumference but a significant reduction in pain experienced after 2 weeks compared to placebo.
Dr. Pumpa KL, the lead author at the University of Canberra in the study to reaffirm the use of topical Arnica gel, for the treatment of pain, evaluated the Arnica effect on the inflammation and muscle damage, and in turn, improve performance in well-trained males experiencing delayed onset muscle soreness (DOMS).
The study included twenty well-trained males matched by maximal oxygen uptake (V̇O2 Max) completed a double-blind randomized placebo-controlled trial.
Topical Arnica was applied to the skin superficial to the quadriceps and gastrocnemius muscles immediately after a downhill running protocol designed to induce DOMS.
Topical Arnica group exerted significantly less pain through muscle tenderness and VAS 72 hours post-exercise and did not affect any performance assessments or markers of muscle damage or inflammation.
Furthermore, topical Arnica used immediately after intense eccentric exercise and for the following 96 hours did not have an effect on performance or blood markers.
The doctoral team after taking into account co and confounders said, " (Topical Arnica applications) demonstrate the possibility of providing pain relief three days post-eccentric exercise".
Taken altogether, topical Arnica gel may be considered a functional herb for the prevention and treatment of muscle pain and damage due to over muscle exercises.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Use of Arnica to relieve pain after carpal-tunnel release surgery by Jeffrey SL, Belcher HJ. (PubMed)
(2) The effects of topical Arnica on performance, pain, and muscle damage after intense eccentric exercise by Pumpa KL, Fallon KE, Bensoussan A, Papalia S.(PubMed)
Saturday, November 2, 2019
Herbal Anise, The Herbal Remedy Which Protects Our Body Against Viral Infectious Diseases
Herbal Anise may be the next potential target to identify the single ingredient medicine for the treatment of viral infection, some scientists suggested.
Infection is a condition that caused the invasion of stimuli and micro pathogens, including viral infection.
A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.
Anti-viral effects are an act of certain substances to cause the destruction of a virus.
In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,
The viral infection o\has been known to carry over some different stage, after successfully attaching to the host cell, the virus to release its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.
The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.
The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.
However, if the immune system can not kill off the invaders with 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region.
The popular herb has been used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, antispasmodic, carminative, digestive, expectorant, stimulant, and tonic agent to treat head-lice and mites, increase blood pressure, prevent formation of gas in the gastrointestinal tract and menstrual cramps, etc.
Besides the main ingredient Anethole, herbal Anise also contains, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
In finding a natural antiviral ingredient or whole without inducing any side effects, researchers examined 3 antiviral and immunostimulating substances (LC1, LC2 and LC3) isolated from a hot water extract of seeds of Pimpinella anisum (herbal Anise).
The isolated substances were found to significantly anti antiviral activities against herpes simplex virus types 1 and 2 (HSV-1 and -2), human cytomegalovirus (HCMV) and measles virus.
Application of LCs interfered with virus adsorption to the host cell surface and directly inactivate viruses.
The result indicated that the isolated compound protected the cell membrane against the penetration of the virus in the initiation of the first phase of infection.
Furthermore, the injection of LCs also prevents the overexpression of protein associated with macrophages infected. In other words, PCs protects the white blood cells associated with the first line of the immune response against the viral invasion.
The results also inhibited the overproduction of the inflammatory cytokines in the acute phase of infection.
Dr. Lee JB, the lead author said, " lignin-carbohydrate-protein complexes from P. anisum possessed potency as functional food ingredients against infectious diseases".
Moreover, the University of Heidelberg investigated the effect of anise oil, dwarf-pine oil and chamomile oil against different thymidine-kinase-positive (aciclovir-sensitive) and thymidine-kinase-negative (aciclovir-resistant) herpes simplex virus type 1 (HSV-1) strains also suggested that essential oil from herbal Anise displays a strong effect against tested viruses.
At maximum noncytotoxic concentrations of the Anise essential oils, significantly reduced the plaque formation by 96.6-99.9% when herpesviruses were preincubated with drugs before attachment to host cells.
Adding essential oil during the replication phase completely wiped out the possibility of viral infectivity.
Compared to the conventional medicine aciclovir, which is effective after attachment inside the infected cells, anise oil affected the virus by interrupting the adsorption of herpesviruses and in a different manner.
The findings suggested that herbal Anise essential oils are capable of exerting a direct effect on HSV and might be useful in the treatment of drug-resistant viruses.
Taken all together, herbal anise may be considered a functional herb for the prevention and an adjunct therapy combined with primary medicine for diseases associated with a viral infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum. by Lee JB, Yamagishi C, Hayashi K, Hayashi T.(PubMed)
(2)Efficacy of anise oil, dwarf-pine oil and chamomile oil against thymidine-kinase-positive and thymidine-kinase-negative herpesviruses by Koch C, Reichling J, Kehm R, Sharaf MM, Zentgraf H, Schneele J, Schnitzler P.(PubMed)
Infection is a condition that caused the invasion of stimuli and micro pathogens, including viral infection.
A viral infection is a disease caused by the successful entering and multiplying of a virus in the body.
Anti-viral effects are an act of certain substances to cause the destruction of a virus.
In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,
The viral infection o\has been known to carry over some different stage, after successfully attaching to the host cell, the virus to release its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.
The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.
The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.
However, if the immune system can not kill off the invaders with 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region.
The popular herb has been used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, antispasmodic, carminative, digestive, expectorant, stimulant, and tonic agent to treat head-lice and mites, increase blood pressure, prevent formation of gas in the gastrointestinal tract and menstrual cramps, etc.
Besides the main ingredient Anethole, herbal Anise also contains, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
In finding a natural antiviral ingredient or whole without inducing any side effects, researchers examined 3 antiviral and immunostimulating substances (LC1, LC2 and LC3) isolated from a hot water extract of seeds of Pimpinella anisum (herbal Anise).
The isolated substances were found to significantly anti antiviral activities against herpes simplex virus types 1 and 2 (HSV-1 and -2), human cytomegalovirus (HCMV) and measles virus.
Application of LCs interfered with virus adsorption to the host cell surface and directly inactivate viruses.
The result indicated that the isolated compound protected the cell membrane against the penetration of the virus in the initiation of the first phase of infection.
Furthermore, the injection of LCs also prevents the overexpression of protein associated with macrophages infected. In other words, PCs protects the white blood cells associated with the first line of the immune response against the viral invasion.
The results also inhibited the overproduction of the inflammatory cytokines in the acute phase of infection.
Dr. Lee JB, the lead author said, " lignin-carbohydrate-protein complexes from P. anisum possessed potency as functional food ingredients against infectious diseases".
Moreover, the University of Heidelberg investigated the effect of anise oil, dwarf-pine oil and chamomile oil against different thymidine-kinase-positive (aciclovir-sensitive) and thymidine-kinase-negative (aciclovir-resistant) herpes simplex virus type 1 (HSV-1) strains also suggested that essential oil from herbal Anise displays a strong effect against tested viruses.
At maximum noncytotoxic concentrations of the Anise essential oils, significantly reduced the plaque formation by 96.6-99.9% when herpesviruses were preincubated with drugs before attachment to host cells.
Adding essential oil during the replication phase completely wiped out the possibility of viral infectivity.
Compared to the conventional medicine aciclovir, which is effective after attachment inside the infected cells, anise oil affected the virus by interrupting the adsorption of herpesviruses and in a different manner.
The findings suggested that herbal Anise essential oils are capable of exerting a direct effect on HSV and might be useful in the treatment of drug-resistant viruses.
Taken all together, herbal anise may be considered a functional herb for the prevention and an adjunct therapy combined with primary medicine for diseases associated with a viral infection.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum. by Lee JB, Yamagishi C, Hayashi K, Hayashi T.(PubMed)
(2)Efficacy of anise oil, dwarf-pine oil and chamomile oil against thymidine-kinase-positive and thymidine-kinase-negative herpesviruses by Koch C, Reichling J, Kehm R, Sharaf MM, Zentgraf H, Schneele J, Schnitzler P.(PubMed)
Aloe Vera Inhibited Symptoms and Progression of Polycystic Ovarian Syndrome With No Side Effects, According to Studies
Scientists may have found a natural whole herb for the treatment of polycystic ovarian syndrome (PCOs) with no side effects some studies suggested.
The polycystic ovarian syndrome is an endocrinologic disease caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries
PCOs induced enlarged ovaries can facilitate the onset of certain complications, including hormone imbalance( excessive androgen), male pattern hair development, acne, irregular period or absence of period, weight gain and infertility.
According to the statistic, polycystic ovary syndrome (PCOs) is a health condition, affecting 1 in 10 women of childbearing age. in the Western world.
The exact causes of polycystic ovary syndrome (PCOs) are unknown, However, according to epidemiological studies, high levels of androgens. and insulin is the 2 characteristics of women with the syndrome.
Women who have the onset of polycystic ovary syndrome (PCOs) also experience additional health problems, including diabetes, high blood pressure, and cholesterol, sleep problem and psychological symptoms of depression and anxiety.
According to the study by Desai BN, Maharjan RH, Nampoothiri LP. almost 70% of PCOS women have abnormal serum lipid levels (dyslipidemia) and 50% of these women are obese.
Several classes of pharmacological agents have been used to manage dyslipidemia. However, studies have shown adverse effects associated with these drugs.
Compared to other risk factors, the genetic preposition has been under intensified studies by many scientists. Dr. N Prapas, the lead author in the study "Genetics of Polycystic Ovary Syndrome" said, "Polycystic ovary syndrome has been proven to be a familial condition....the role of genetic factors in PCOS is strongly supported" and
" Some genes (such as Gly972Arg, CAPN10) have shown altered expression suggesting that the genetic abnormality in PCOS affects signal transduction pathways controlling steroidogenesis, steroid hormones action, gonadotrophin action and regulation, insulin action and secretion, energy homeostasis, chronic inflammation, and others".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
The plant has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
The herb also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding a natural ingredient or whole food for the treatment of polycystic ovarian syndrome (PCOs) with no side effects, researchers examine the effects of Aloe vera in Charles Foster female rats induced-PCOs PCOS by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days).
All rats before injection of the Aloe vera expressed a significant increase of hyperglycemia and 90% rats also showed elevated plasma triglycerides, elevated LDL cholesterol levels, and lowered plasma HDL cholesterol levels, an indication of a dyslipidemic profile.
PCOS positive rats with an aberrant lipid profile were selected to the treatment with AVG formulation (1 ml (10 mg)/day, 30 days) administered orally.
The infection of AVG in PCOS rats exhibited a significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol.
The gel treatment also completely restore the abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities.
These results firmly suggested AVG which contains a high amount of phyto components processes an anti-hyperlipidemic effect not only on PCOS but also on the associated metabolic complication: dyslipidemia.
Continuously, in the study included five-month-old Charles Foster female rats were orally fed with letrozole, a non-steroidal aromatase inhibitor, to induce PCOS, researchers once again confirmed that
* Aloe vera gel formulation (1 ml dose daily for 45 days) restores their estrus cyclicity, glucose sensitivity, and steroidogenic activity.
* Co-treatment of the inductive agent (letrozole) with the Aloe vera gel prevented the development of the PCO phenotype caused by the injection of the inductive agent (letrozole).
Dr.Maharjan R, the lead author at the final day of the experiment said, " Aloe vera gel formulation exerts a protective effect against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity".
Taken altogether, Aloe Vera may be considered a functional food for the prevention and treatment of
polycystic ovarian syndrome (PCOs) without inducing any side effects,
However, oral administration in high amounts of Aloe vera should only be prescribed by the experts in the related field
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model (PubMed)
(4) Genetics of Polycystic Ovary Syndrome by N Prapas, A Karkanaki, I Prapas, I Kalogiannidis, I Katsikis, and D Panidis. (PMC)
The polycystic ovarian syndrome is an endocrinologic disease caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries
PCOs induced enlarged ovaries can facilitate the onset of certain complications, including hormone imbalance( excessive androgen), male pattern hair development, acne, irregular period or absence of period, weight gain and infertility.
According to the statistic, polycystic ovary syndrome (PCOs) is a health condition, affecting 1 in 10 women of childbearing age. in the Western world.
The exact causes of polycystic ovary syndrome (PCOs) are unknown, However, according to epidemiological studies, high levels of androgens. and insulin is the 2 characteristics of women with the syndrome.
Women who have the onset of polycystic ovary syndrome (PCOs) also experience additional health problems, including diabetes, high blood pressure, and cholesterol, sleep problem and psychological symptoms of depression and anxiety.
According to the study by Desai BN, Maharjan RH, Nampoothiri LP. almost 70% of PCOS women have abnormal serum lipid levels (dyslipidemia) and 50% of these women are obese.
Several classes of pharmacological agents have been used to manage dyslipidemia. However, studies have shown adverse effects associated with these drugs.
Compared to other risk factors, the genetic preposition has been under intensified studies by many scientists. Dr. N Prapas, the lead author in the study "Genetics of Polycystic Ovary Syndrome" said, "Polycystic ovary syndrome has been proven to be a familial condition....the role of genetic factors in PCOS is strongly supported" and
" Some genes (such as Gly972Arg, CAPN10) have shown altered expression suggesting that the genetic abnormality in PCOS affects signal transduction pathways controlling steroidogenesis, steroid hormones action, gonadotrophin action and regulation, insulin action and secretion, energy homeostasis, chronic inflammation, and others".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
The plant has become very popular for commercial cultivation due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
The herb also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding a natural ingredient or whole food for the treatment of polycystic ovarian syndrome (PCOs) with no side effects, researchers examine the effects of Aloe vera in Charles Foster female rats induced-PCOs PCOS by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days).
All rats before injection of the Aloe vera expressed a significant increase of hyperglycemia and 90% rats also showed elevated plasma triglycerides, elevated LDL cholesterol levels, and lowered plasma HDL cholesterol levels, an indication of a dyslipidemic profile.
PCOS positive rats with an aberrant lipid profile were selected to the treatment with AVG formulation (1 ml (10 mg)/day, 30 days) administered orally.
The infection of AVG in PCOS rats exhibited a significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol.
The gel treatment also completely restore the abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities.
These results firmly suggested AVG which contains a high amount of phyto components processes an anti-hyperlipidemic effect not only on PCOS but also on the associated metabolic complication: dyslipidemia.
Continuously, in the study included five-month-old Charles Foster female rats were orally fed with letrozole, a non-steroidal aromatase inhibitor, to induce PCOS, researchers once again confirmed that
* Aloe vera gel formulation (1 ml dose daily for 45 days) restores their estrus cyclicity, glucose sensitivity, and steroidogenic activity.
* Co-treatment of the inductive agent (letrozole) with the Aloe vera gel prevented the development of the PCO phenotype caused by the injection of the inductive agent (letrozole).
Dr.Maharjan R, the lead author at the final day of the experiment said, " Aloe vera gel formulation exerts a protective effect against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity".
Taken altogether, Aloe Vera may be considered a functional food for the prevention and treatment of
polycystic ovarian syndrome (PCOs) without inducing any side effects,
However, oral administration in high amounts of Aloe vera should only be prescribed by the experts in the related field
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(3) Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model (PubMed)
(4) Genetics of Polycystic Ovary Syndrome by N Prapas, A Karkanaki, I Prapas, I Kalogiannidis, I Katsikis, and D Panidis. (PMC)
Friday, November 1, 2019
Turmeric Protects the Skin Against Atopic Dermatitis in Vivo
Atopic dermatitis, a type of eczema is skin condition associated with skin red patches and itchy.
Children are at a higher risk of atopic dermatitis compared to adults.
Most cases of atopic dermatitis are healed by itself or by rehydrating the skin with topical forms of petroleum jelly, such as Vaseline.
However, in serious cases, topical steroids to reduce inflammation and control itching may be prescribed. In patients with itching scratch, oral antihistamines may be recommended.
Besides red patches and itching on the affected area, patients may also experience symptoms of dry skin, small bumps containing fluids, cracked and scaly, sensitive, swollen skin due to scratching.
If you experience some of the aforementioned symptoms, you have atopic dermatitis. Please check with your doctor to rule out the possibility.
Epidemiologically, atopic dermatitis has been found to associate with exposure to allergens such as pollen, pet dander or peanuts, or by stress, dry skin, and infection.
Some atopic dermatitis may also be triggered by skin irritants such as some fabrics, soaps and household cleaners.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On findings a potential ingredient or whole food for the treatment of atopic dermatitis (AD), researchers examined the effects of p-hydroxycinnamic acid (HCA) isolated from the roots of Curcuma longa.
In a mouse model of ear AD, p-hydroxycinnamic acid (HCA) exerted a significant activity against ear thickening, immune-cell infiltration, production of AD-promoting immunoregulatory cytokines in ear tissues.
Futhermore, HCA also inhibited the increased spleen and draining lymph node size and weight in the induction of the increased pro-inflammatory cytokines production.
In vitro, HCV inhibited the CD4+ T cells against the imbalance of Th1 and Th2 in facilitating the production of cytokines.
Based on the results, researchers said, " HCA may be of therapeutic potential for AD as it acts by suppressing keratinocyte activation and downregulating T-cell differentiation and cytokine production".
In order to reveal more information about turmeric anti-allergic effects, researchers investigated herbal medicine in the attenuation of food allergy symptoms in an animal model.
Selected mice immunized with intraperitoneal ovalbumin (OVA) and alum were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30 mg/kg) for 16 days.
Turmeric treated group significantly attenuated food allergy symptoms by decreasing rectal temperature and anaphylactic response induced by OVA, compared to the low improvement of the curcumin group.
Turmeric also inhibited the antibodies produced by the immune system that can lead to inflammatory processes( IgE, IgG1) and mMCP-1 levels, a marker of food allergy increased by OVA.
Furthermore, turmeric balanced the levels of type 1 and 2 helper cell (Th2)-against the production of pro-inflammatory cytokines.
The findings suggested that turmeric exhibits an anti-allergic effect through reduced type 2 helper cell (Th2)-related cytokines and enhanced a Th1-related cytokine.
According to the results, researchers, after taking into account co and confounders wrote, "Turmeric significantly ameliorated food allergic symptoms in a mouse model of food allergy".
And, "The turmeric as an anti-allergic agent showed immune regulatory effects through maintaining Th1/Th2 immune balance, whereas curcumin appeared immune suppressive effects".
Taken altogether, turmeric may be considered supplements for the treatment of atopic dermatitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation by Lee HS1, Choi EJ2, Lee KS1, Kim HR1, Na BR1, Kwon MS1, Jeong GS3, Choi HG4, Choi EY5, Jun CD. (PubMed)
(2) Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type 1/type 2 helper T cells (Th1/Th2) balance in a mouse model of food allergy by Shin HS1, See HJ2, Jung SY2, Choi DW2, Kwon DA2, Bae MJ3, Sung KS2, Shon DH. (PubMed)
Children are at a higher risk of atopic dermatitis compared to adults.
Most cases of atopic dermatitis are healed by itself or by rehydrating the skin with topical forms of petroleum jelly, such as Vaseline.
However, in serious cases, topical steroids to reduce inflammation and control itching may be prescribed. In patients with itching scratch, oral antihistamines may be recommended.
Besides red patches and itching on the affected area, patients may also experience symptoms of dry skin, small bumps containing fluids, cracked and scaly, sensitive, swollen skin due to scratching.
If you experience some of the aforementioned symptoms, you have atopic dermatitis. Please check with your doctor to rule out the possibility.
Epidemiologically, atopic dermatitis has been found to associate with exposure to allergens such as pollen, pet dander or peanuts, or by stress, dry skin, and infection.
Some atopic dermatitis may also be triggered by skin irritants such as some fabrics, soaps and household cleaners.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On findings a potential ingredient or whole food for the treatment of atopic dermatitis (AD), researchers examined the effects of p-hydroxycinnamic acid (HCA) isolated from the roots of Curcuma longa.
In a mouse model of ear AD, p-hydroxycinnamic acid (HCA) exerted a significant activity against ear thickening, immune-cell infiltration, production of AD-promoting immunoregulatory cytokines in ear tissues.
Futhermore, HCA also inhibited the increased spleen and draining lymph node size and weight in the induction of the increased pro-inflammatory cytokines production.
In vitro, HCV inhibited the CD4+ T cells against the imbalance of Th1 and Th2 in facilitating the production of cytokines.
Based on the results, researchers said, " HCA may be of therapeutic potential for AD as it acts by suppressing keratinocyte activation and downregulating T-cell differentiation and cytokine production".
In order to reveal more information about turmeric anti-allergic effects, researchers investigated herbal medicine in the attenuation of food allergy symptoms in an animal model.
Selected mice immunized with intraperitoneal ovalbumin (OVA) and alum were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30 mg/kg) for 16 days.
Turmeric treated group significantly attenuated food allergy symptoms by decreasing rectal temperature and anaphylactic response induced by OVA, compared to the low improvement of the curcumin group.
Turmeric also inhibited the antibodies produced by the immune system that can lead to inflammatory processes( IgE, IgG1) and mMCP-1 levels, a marker of food allergy increased by OVA.
Furthermore, turmeric balanced the levels of type 1 and 2 helper cell (Th2)-against the production of pro-inflammatory cytokines.
The findings suggested that turmeric exhibits an anti-allergic effect through reduced type 2 helper cell (Th2)-related cytokines and enhanced a Th1-related cytokine.
According to the results, researchers, after taking into account co and confounders wrote, "Turmeric significantly ameliorated food allergic symptoms in a mouse model of food allergy".
And, "The turmeric as an anti-allergic agent showed immune regulatory effects through maintaining Th1/Th2 immune balance, whereas curcumin appeared immune suppressive effects".
Taken altogether, turmeric may be considered supplements for the treatment of atopic dermatitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Oral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation by Lee HS1, Choi EJ2, Lee KS1, Kim HR1, Na BR1, Kwon MS1, Jeong GS3, Choi HG4, Choi EY5, Jun CD. (PubMed)
(2) Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type 1/type 2 helper T cells (Th1/Th2) balance in a mouse model of food allergy by Shin HS1, See HJ2, Jung SY2, Choi DW2, Kwon DA2, Bae MJ3, Sung KS2, Shon DH. (PubMed)
Herbal Andrographis inhibits the Risk, Progression of Colitis
Herbal Andrographis may have potential and profound effects in reducing risk and treatment of colitis with no side effects, scientists suggested
Colitis is a condition of inflammation of the large intestine, including the colon, caecum, and rectum.
There is a number of causes of the disease, including infection, inflammatory bowel disease, and allergic reactions.
Other types of colitis include
* Microscopic colitis a condition referred to collagenous colitis and lymphocytic colitis, two related medical conditions which cause diarrhea.
* Ischemic colitis, another colon infection which may also go away with a mild treatment, such as a short-term liquid diet and antibiotics.
If you are experiencing some of the symptoms such as persistent abdominal pain, diarrhea and cramping, dehydration, selling of joint, eye inflammation and fever or chill, you may have colitis. Please check with your doctor to rule out the possibility of the disease.
Dr. Winther KV in the study to examine the survival and cause-specific mortality in ulcerative colitis, including 1160 patients diagnosed with ulcerative colitis between 1962 and 1987 was followed-up until 1997 to describe survival and cause-specific mortality.
At that span, a total of 261 deaths occurred, not significantly different from the expected number of 249 (SMR, 1.05; 95% CI, 0.92-1.19). The median age at death among men was 70 years (range, 6-96 years) and among women 74 years (range, 25-96 years).
The mortality was increased in patients with pulmonary embolism and pneumonia.
The doctor team wrote, in the final report, "Despite an overall normal life expectancy for patients with ulcerative colitis, patients >50 years of age and with extensive colitis at diagnosis had increased mortality within the first 2 years after diagnosis, owing to colitis-associated postoperative complications and comorbidity".
The results clearly suggested that patients with colitis are at increased risk to die due to the complication of other diseases, particularly, in the first 2 years of diagnosis.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chickenpox, etc.
Besides the main ingredient andrographolides, giving the plant a bitter taste, other ingredients includediterpene lactones, such as neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
In order to reaffirm the use of extracts of the plant Andrographis paniculata anti-inflammatory diseases in Asian countries, researchers examined the effects of HMPL-004 (A. paniculata extract) against colitis in mice model induced by injection of methylcellulose (MC).
Before the application of HMPL-004, mice treated with MC developed colitis within 4-7 weeks, accompanied by weight gain and severe intestinal inflammation.
HMPL-004-treated mice inhibited lose weight and displayed only very mild intestinal inflammation.
The inflammatory cytokines caused by the injection of MC also significantly decreased after the treatment of HMPL-004.
Higher percentages of naĂŻve CD4(+) T cells in the lamina propria of HMPL-004-treated mice compared to MC mice.
Furthermore at the early timepoints HMPL-004-treated mice have significantly reduced splenic cell counts, reduced inflammatory markers, and reduced pro-inflammatory expression.
Moreover, HMPL-004 inhibited the proliferation of CD4 T cells that cause immune response differentiation into TH1/TH17 cells that have the capacity to cause inflammation and autoimmune disease in vitro.
The results firmly suggested that HMPL-004 has a potential effect on inflammatory diseases, particularly in inflammatory bowel disease and colitis.
The research team at the final report wrote, "HMPL-004 inhibits the development of chronic colitis by affecting early T-cell proliferation, differentiation, and TH(1)/TH(17) responses in a T-cell-driven model of colitis, presenting a unique mechanism of action".
Also, the Hutchison Medipharma Ltd.in a recent randomized, double-blind, multicentre, 8-week parallel-group study of HMPL-004, to learn more about the anti-inflammatory activity examined the Andrographis paniculata extract against mild to moderate ulcerative colitis (UC).
Compared to 16% and 82% efficacy of 4500 mg/day of slow-release mesalazine (mesalamine) granules in patients with mild-to-moderately active ulcerative colitis, the application of HMPL-004 exerted a more tenant effect on 21% and 76%, respectively.
By colonoscopy, remission and response were seen in 28% and 74% of HMPL-004-treated patients and 24% and 71% of mesalazine-treated patients, respectively.
The finding strongly supported HMPL-004 is an efficacious alternative to mesalazine in ulcerative colitis.
Taken altogether, herbal Andrographis may be considered a functional remedy for the prevention and treatment of colitis, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T-cell proliferation and TH1/TH17 responses by Michelsen KS, Wong MH, Ko B, Thomas LS, Dhall D, Targan SR.(PubMed)
(2) Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine by Tang T1, Targan SR, Li ZS, Xu C, Byers VS, Sandborn WJ. (PubMed)
(3) Survival and cause-specific mortality in ulcerative colitis: follow-up of a population-based cohort in Copenhagen County by Winther KV1, Jess T, Langholz E, Munkholm P, Binder V.(PubMed)
Colitis is a condition of inflammation of the large intestine, including the colon, caecum, and rectum.
There is a number of causes of the disease, including infection, inflammatory bowel disease, and allergic reactions.
Other types of colitis include
* Microscopic colitis a condition referred to collagenous colitis and lymphocytic colitis, two related medical conditions which cause diarrhea.
* Ischemic colitis, another colon infection which may also go away with a mild treatment, such as a short-term liquid diet and antibiotics.
If you are experiencing some of the symptoms such as persistent abdominal pain, diarrhea and cramping, dehydration, selling of joint, eye inflammation and fever or chill, you may have colitis. Please check with your doctor to rule out the possibility of the disease.
Dr. Winther KV in the study to examine the survival and cause-specific mortality in ulcerative colitis, including 1160 patients diagnosed with ulcerative colitis between 1962 and 1987 was followed-up until 1997 to describe survival and cause-specific mortality.
At that span, a total of 261 deaths occurred, not significantly different from the expected number of 249 (SMR, 1.05; 95% CI, 0.92-1.19). The median age at death among men was 70 years (range, 6-96 years) and among women 74 years (range, 25-96 years).
The mortality was increased in patients with pulmonary embolism and pneumonia.
The doctor team wrote, in the final report, "Despite an overall normal life expectancy for patients with ulcerative colitis, patients >50 years of age and with extensive colitis at diagnosis had increased mortality within the first 2 years after diagnosis, owing to colitis-associated postoperative complications and comorbidity".
The results clearly suggested that patients with colitis are at increased risk to die due to the complication of other diseases, particularly, in the first 2 years of diagnosis.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chickenpox, etc.
Besides the main ingredient andrographolides, giving the plant a bitter taste, other ingredients includediterpene lactones, such as neoandrographolide, andrographiside, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoinds viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
In order to reaffirm the use of extracts of the plant Andrographis paniculata anti-inflammatory diseases in Asian countries, researchers examined the effects of HMPL-004 (A. paniculata extract) against colitis in mice model induced by injection of methylcellulose (MC).
Before the application of HMPL-004, mice treated with MC developed colitis within 4-7 weeks, accompanied by weight gain and severe intestinal inflammation.
HMPL-004-treated mice inhibited lose weight and displayed only very mild intestinal inflammation.
The inflammatory cytokines caused by the injection of MC also significantly decreased after the treatment of HMPL-004.
Higher percentages of naĂŻve CD4(+) T cells in the lamina propria of HMPL-004-treated mice compared to MC mice.
Furthermore at the early timepoints HMPL-004-treated mice have significantly reduced splenic cell counts, reduced inflammatory markers, and reduced pro-inflammatory expression.
Moreover, HMPL-004 inhibited the proliferation of CD4 T cells that cause immune response differentiation into TH1/TH17 cells that have the capacity to cause inflammation and autoimmune disease in vitro.
The results firmly suggested that HMPL-004 has a potential effect on inflammatory diseases, particularly in inflammatory bowel disease and colitis.
The research team at the final report wrote, "HMPL-004 inhibits the development of chronic colitis by affecting early T-cell proliferation, differentiation, and TH(1)/TH(17) responses in a T-cell-driven model of colitis, presenting a unique mechanism of action".
Also, the Hutchison Medipharma Ltd.in a recent randomized, double-blind, multicentre, 8-week parallel-group study of HMPL-004, to learn more about the anti-inflammatory activity examined the Andrographis paniculata extract against mild to moderate ulcerative colitis (UC).
Compared to 16% and 82% efficacy of 4500 mg/day of slow-release mesalazine (mesalamine) granules in patients with mild-to-moderately active ulcerative colitis, the application of HMPL-004 exerted a more tenant effect on 21% and 76%, respectively.
By colonoscopy, remission and response were seen in 28% and 74% of HMPL-004-treated patients and 24% and 71% of mesalazine-treated patients, respectively.
The finding strongly supported HMPL-004 is an efficacious alternative to mesalazine in ulcerative colitis.
Taken altogether, herbal Andrographis may be considered a functional remedy for the prevention and treatment of colitis, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T-cell proliferation and TH1/TH17 responses by Michelsen KS, Wong MH, Ko B, Thomas LS, Dhall D, Targan SR.(PubMed)
(2) Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine by Tang T1, Targan SR, Li ZS, Xu C, Byers VS, Sandborn WJ. (PubMed)
(3) Survival and cause-specific mortality in ulcerative colitis: follow-up of a population-based cohort in Copenhagen County by Winther KV1, Jess T, Langholz E, Munkholm P, Binder V.(PubMed)
Artichoke Protects Us Against Heart Disease, According to Studies
Artichoke may be used as a natural and herbal remedy for the treatment of heart disease with no side effects, according to studies.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
Most common risk factors associated with heart disease are aging, family history with heart disease, metabolic syndrome, high blood pressure and cholesterol, obesity, smoking, and stress epidemiologically.
However, most people with some of the above risk factors have never developed heart disease. Symptoms of heart disease completely depend on the infected location.
Some researchers suggested that by making a change in lifestyle accompanied by moderate physical activity such as walking, the risk of heart disease can be prevented.
The American College of Cardiology wrote in the article of Heart Disease: Lifestyle Changes to Lower Risk. "Start slowly, and go at a pace you can manage. Try to do at least 2½ hours of moderate exercise a week. One way to do this is to be active 30 minutes a day, at least 5 days a week".
"Healthy eating starts with learning new ways to eat, such as adding more fresh fruits, vegetables, and whole grains and cutting back on foods that have a lot of saturated fat, sodium, and sugar"
"Getting active and eating a healthy diet can help you lose extra weight and quit smoking"
Finally, the article continued, "Even though you are taking medicine, it is always important to make lifestyle changes that keep your heart and your body healthy".
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae, native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and for the treatment of digestive disorders, abdominal pain gas and bloating, etc.
Finding a natural ingredient for the treatment of cardiovascular diseases has been a dream of many scientists. Researchers at the joint study led by the IRCCS San Raffaele Pisana, examined the effects of vegetables, including artichoke on CVD.
The joint study included a total of 38 subjects at risk of CVD. After, a week of the run-in period, participants were randomly assigned to one of the following 4-week interventions: low vegetable consumption (800 g of vegetables/week) or high vegetable consumption (4200 g of vegetables/week).
According to the assays that record immunological, and antioxidant markers, leukocyte and lymphocyte expression of the gut-homing β7 integrin, there were no significant changes detected in clinical, immunological, and antioxidant markers in biological samples, except for an increase in white blood cell count for the low vegetable consumption group.
The immune system's innate and adaptive immune responses play an essential role in the development and progression of cardiovascular diseases by inhibiting the pro-inflammatory expression.
The vegetable consumption group exerts a CVD protective effect in modulating markers of immune function and antioxidant status in patients with CVD. In healthy individuals, the intake of vegetables does not induce a change of both antioxidant and inflammatory markers associated with immune function, particularly in nonsmoking men.
These results strongly suggested that vegetables modulate the function of the immune system according to the needs of the body.
In other to reveal more information about artichoke anti CVD activity, Dr. Rondanelli M and colleagues at the University of Pavia investigated the artichoke extracts on the cardiovascular disease on both animals and man.
Injection of artichoke not only reduced the levels of cholesterol in the bloodstream through its hypolipidemic activity but also inhibited the expression of high blood glucose and free radicals through the antioxidant and hypoglycemic activity.
The results indicated artichoke reduced the risk and progression of cardiovascular disease by improving the production of antioxidant enzymes against oxidative stress in the initiation of low-grade inflammation, a hallmark of CVD.
Futhermore, artichoke also decreases the levels of blood cholesterol and glucose, the cluster conditions associated with the risk CVD, epidemiologically.
Taken altogether, artichoke which processes anti cardiovascular disease activity through several mechanisms may be considered a functional remedy for the prevention and treatment of cardiovascular diseases, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effects of High Consumption of Vegetables on Clinical, Immunological, and Antioxidant Markers in Subjects at Risk of Cardiovascular Diseases by Peluso I1, Raguzzini A1, Catasta G1, Cammisotto V1, Perrone A1, Tomino C2, Toti E1, Serafini M. (Hindawi)
(2) Health-promoting properties of artichoke in preventing cardiovascular disease by its lipidic and glycemic-reducing action by Rondanelli M1, Monteferrario F, Perna S, Faliva MA, Opizzi A. (PubMed)
(3) Heart Disease: Lifestyle Changes to Lower Risk by The American College of Cardiology
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
Most common risk factors associated with heart disease are aging, family history with heart disease, metabolic syndrome, high blood pressure and cholesterol, obesity, smoking, and stress epidemiologically.
However, most people with some of the above risk factors have never developed heart disease. Symptoms of heart disease completely depend on the infected location.
Some researchers suggested that by making a change in lifestyle accompanied by moderate physical activity such as walking, the risk of heart disease can be prevented.
The American College of Cardiology wrote in the article of Heart Disease: Lifestyle Changes to Lower Risk. "Start slowly, and go at a pace you can manage. Try to do at least 2½ hours of moderate exercise a week. One way to do this is to be active 30 minutes a day, at least 5 days a week".
"Healthy eating starts with learning new ways to eat, such as adding more fresh fruits, vegetables, and whole grains and cutting back on foods that have a lot of saturated fat, sodium, and sugar"
"Getting active and eating a healthy diet can help you lose extra weight and quit smoking"
Finally, the article continued, "Even though you are taking medicine, it is always important to make lifestyle changes that keep your heart and your body healthy".
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae, native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and for the treatment of digestive disorders, abdominal pain gas and bloating, etc.
Finding a natural ingredient for the treatment of cardiovascular diseases has been a dream of many scientists. Researchers at the joint study led by the IRCCS San Raffaele Pisana, examined the effects of vegetables, including artichoke on CVD.
The joint study included a total of 38 subjects at risk of CVD. After, a week of the run-in period, participants were randomly assigned to one of the following 4-week interventions: low vegetable consumption (800 g of vegetables/week) or high vegetable consumption (4200 g of vegetables/week).
According to the assays that record immunological, and antioxidant markers, leukocyte and lymphocyte expression of the gut-homing β7 integrin, there were no significant changes detected in clinical, immunological, and antioxidant markers in biological samples, except for an increase in white blood cell count for the low vegetable consumption group.
The immune system's innate and adaptive immune responses play an essential role in the development and progression of cardiovascular diseases by inhibiting the pro-inflammatory expression.
The vegetable consumption group exerts a CVD protective effect in modulating markers of immune function and antioxidant status in patients with CVD. In healthy individuals, the intake of vegetables does not induce a change of both antioxidant and inflammatory markers associated with immune function, particularly in nonsmoking men.
These results strongly suggested that vegetables modulate the function of the immune system according to the needs of the body.
In other to reveal more information about artichoke anti CVD activity, Dr. Rondanelli M and colleagues at the University of Pavia investigated the artichoke extracts on the cardiovascular disease on both animals and man.
Injection of artichoke not only reduced the levels of cholesterol in the bloodstream through its hypolipidemic activity but also inhibited the expression of high blood glucose and free radicals through the antioxidant and hypoglycemic activity.
The results indicated artichoke reduced the risk and progression of cardiovascular disease by improving the production of antioxidant enzymes against oxidative stress in the initiation of low-grade inflammation, a hallmark of CVD.
Futhermore, artichoke also decreases the levels of blood cholesterol and glucose, the cluster conditions associated with the risk CVD, epidemiologically.
Taken altogether, artichoke which processes anti cardiovascular disease activity through several mechanisms may be considered a functional remedy for the prevention and treatment of cardiovascular diseases, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effects of High Consumption of Vegetables on Clinical, Immunological, and Antioxidant Markers in Subjects at Risk of Cardiovascular Diseases by Peluso I1, Raguzzini A1, Catasta G1, Cammisotto V1, Perrone A1, Tomino C2, Toti E1, Serafini M. (Hindawi)
(2) Health-promoting properties of artichoke in preventing cardiovascular disease by its lipidic and glycemic-reducing action by Rondanelli M1, Monteferrario F, Perna S, Faliva MA, Opizzi A. (PubMed)
(3) Heart Disease: Lifestyle Changes to Lower Risk by The American College of Cardiology
Onion Promotes Healthy Gut Microbiota
Gut microbiota is a community of microbes living in the gastrointestinal tract, including at least 1000 different species of known bacteria with more than 3 million genes.
In a healthy individual, the ratio of good and bad microbes in the gut are balanced. However, people who have a psychological condition such as anxiety, and depression, and are under constant stress and long-term use of antibiotics, particularly your diet may have a negative impact on the ratio.
More precisely, under normal conditions, gut microbiota plays a critical role in overall health,
* Gut microbiota improves the absorption of the dietary nutrients of the digestive system
* Gut microbiota protects the body against xenobiotics and drug toxicity through facilitating the excretion.
* Gut microbiota also maintains the structural integrity of the gut mucosal barrier by enhancing the epithelial cells that protect the intestine against invasive pathogens and ensure the function of intestinal in nutrients adsorption.
* Gut microbiota interacts with the immune system against inflammatory immune disorders and inhibits the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
However, imbalanced the ratio of gut microbiota may have a negative impact on human health and diseases.
Epidemiological studies suggested imbalanced gut microbiota dysbiosis found in overweight and obese has been found to promote diet-induced obesity and metabolic complications.
Dr. KarinaAl-Ass wrote, "Obesity is a worldwide epidemiologic syndrome characterized by fat mass accumulation, mainly visceral fat. Current thinking considers the potential role of gut microbiota on the development of obesity and its related comorbidities"
And " Gut microbiota can influence energy extraction from food, lipid metabolism, immune response, and endocrine functions and its profile has shown to differs between obese and lean subjects".
A recent joint study led by the Tianjin Medical University, General Hospital, onion supplement may be potent to improve gut microflora and intestinal histomorphology on an animal model.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
The study included a total of 300 and 12-day old broiler chicks (Ross) that randomly divided into four groups as A served as the control without any supplementation, and B, C, and D received supplemented with onion powder at the rate of 1.5, 2 and 2.5g/kg of feed respectively.
Based on the tested results,* Supplementation of onion exerted a significantly (P<0.05) increased weight gain and feed consumption compared to control.
* Furthermore, supplementation of onion significantly inhibited the population of E. coli and increased significantly Lactobacillus and Streptococcus species.
In other words, onion supplement promotes colon health by improving the ratio of gut microbiota.
* More importantly, injection of onion supplement also significantly increases the morphometry of length, width, crypt depth and surface area of the villus in duodenum, jejunum, and ileum of the small intestine associated with the colon health optimization.
Based on the findings, researchers said, "onion supplementation in broiler produced a positive effect on performance, gut microflora, and intestinal histomorphology".
Taken altogether, onion processed a higher mount of onionin A (ONA) may be considered a remedy for the promotion of colon health, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of Quercetin Monoglycosides on Oxidative Stress and Gut MicrobiotaDiversity in Mice with Dextran Sodium Sulphate-Induced Colitis by Hong Z1, Piao M. (PubMed)
(2) In vivo effects of Allium cepa L. on the selected gut microflora and intestinal histomorphology in broiler by Ur Rahman S1, Khan S1, Chand N1, Sadique U2, Khan RU. (PubMed)
(3) Gut microbiota and obesity by Karina Al-Assal, Ana Cristina Martinez, Raquel SusanaTorrinhas, Camila Cardinelli, Dan Waitzberg. (Science Direct)
In a healthy individual, the ratio of good and bad microbes in the gut are balanced. However, people who have a psychological condition such as anxiety, and depression, and are under constant stress and long-term use of antibiotics, particularly your diet may have a negative impact on the ratio.
More precisely, under normal conditions, gut microbiota plays a critical role in overall health,
* Gut microbiota improves the absorption of the dietary nutrients of the digestive system
* Gut microbiota protects the body against xenobiotics and drug toxicity through facilitating the excretion.
* Gut microbiota also maintains the structural integrity of the gut mucosal barrier by enhancing the epithelial cells that protect the intestine against invasive pathogens and ensure the function of intestinal in nutrients adsorption.
* Gut microbiota interacts with the immune system against inflammatory immune disorders and inhibits the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
However, imbalanced the ratio of gut microbiota may have a negative impact on human health and diseases.
Epidemiological studies suggested imbalanced gut microbiota dysbiosis found in overweight and obese has been found to promote diet-induced obesity and metabolic complications.
Dr. KarinaAl-Ass wrote, "Obesity is a worldwide epidemiologic syndrome characterized by fat mass accumulation, mainly visceral fat. Current thinking considers the potential role of gut microbiota on the development of obesity and its related comorbidities"
And " Gut microbiota can influence energy extraction from food, lipid metabolism, immune response, and endocrine functions and its profile has shown to differs between obese and lean subjects".
A recent joint study led by the Tianjin Medical University, General Hospital, onion supplement may be potent to improve gut microflora and intestinal histomorphology on an animal model.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
The study included a total of 300 and 12-day old broiler chicks (Ross) that randomly divided into four groups as A served as the control without any supplementation, and B, C, and D received supplemented with onion powder at the rate of 1.5, 2 and 2.5g/kg of feed respectively.
Based on the tested results,* Supplementation of onion exerted a significantly (P<0.05) increased weight gain and feed consumption compared to control.
* Furthermore, supplementation of onion significantly inhibited the population of E. coli and increased significantly Lactobacillus and Streptococcus species.
In other words, onion supplement promotes colon health by improving the ratio of gut microbiota.
* More importantly, injection of onion supplement also significantly increases the morphometry of length, width, crypt depth and surface area of the villus in duodenum, jejunum, and ileum of the small intestine associated with the colon health optimization.
Based on the findings, researchers said, "onion supplementation in broiler produced a positive effect on performance, gut microflora, and intestinal histomorphology".
Taken altogether, onion processed a higher mount of onionin A (ONA) may be considered a remedy for the promotion of colon health, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of Quercetin Monoglycosides on Oxidative Stress and Gut MicrobiotaDiversity in Mice with Dextran Sodium Sulphate-Induced Colitis by Hong Z1, Piao M. (PubMed)
(2) In vivo effects of Allium cepa L. on the selected gut microflora and intestinal histomorphology in broiler by Ur Rahman S1, Khan S1, Chand N1, Sadique U2, Khan RU. (PubMed)
(3) Gut microbiota and obesity by Karina Al-Assal, Ana Cristina Martinez, Raquel SusanaTorrinhas, Camila Cardinelli, Dan Waitzberg. (Science Direct)
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