Wednesday, November 6, 2019

Herbal Aloe Vera, a Potent Mouth Wash for the Prevention and Treatment of Gingivitis with No Side Effects

Scientists may have found a low-cost natural gel or mouthwash with no side effects, according to the studies.

Gingivitis is a condition characterized by the inflammation of gum or gum disease.

Most causes of gingivitis in the general population are associated with long-term poor hygiene.

However, People who are smoking and chewing tobacco, having certain medical conditions such as diabetes or consuming oral contraceptives, steroids, anticonvulsants, calcium channel blockers are also at a higher risk of gingivitis.

Untreated gingivitis can lead to a serious infection of periodontitis, the major causes of tooth loss in adults, according to the American Dental Association.

Most cases of untreated gingivitis can also induce complications of bad breath, persistent gum bleeding, and receding gums.

Treatments of gingivitis are to control the infection and totally depending on the stages of the disease. However, regardless of the type of treatment, patients are all required to keep up good daily care at home.

People who smoke or tobacco chewing in some cases may be advised to quit or reduce the amount of intake per day.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.

The herbal plant is also one of many popular herbs studied in scientific ways with some conflicting results.

The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

With an aim to find a natural compound for the prevention and treatment of gingivitis with no side effects, researchers at the University of Fortaleza examined the effect of Aloe vera in a randomized, parallel and double-blind clinical trial.

The study included 30 participants randomly allocated to the test group (n=15) dentifrice containing Aloe vera - or the control group (n=15) - fluoridated dentifrice and participants were asked to brush their teeth with the control or test dentifrice, three times a day, during a 30-day period.

According to the Plaque index (PI) and gingival bleeding index (GBI) assessed at days 0 and 30, a significant reduction on plaque and gingivitis in both groups, but no statistically significant difference was observed among them.

The result suggested that the dentifrice containing Aloe vera exerted similar effects as that of fluoridated dentifrice against plaque and gingivitis.

Furthermore, a total of 45 patients who were diagnosed with plaque-induced gingivitis included in the study. were divided into three groups with fifteen patients in each group to evaluate the effects of Aloe vera.

Group 1 was asked to rinse with 10 ml of aloe vera mouthwash twice daily for three months. Group 2 was treated with scaling only. Group 3 patients were asked to rinse with aloe vera mouthwash and scaling was done.

According to the data obtained at the baseline, the end of the first month, and the end of the third month, all three groups showed a significant reduction in gingival inflammation. Aloe vera mouthwash showed the greatest effect compared to other groups.

The results were attributed to the Aloe vera anti-inflammatory activity.

Dr.Ajmera N, the lead scientist said, "it (Aloe vera) can be used as an adjunct to mechanical therapy for treating plaque-induced gingivitis".

Taken altogether, herbal Aloe vera may be used as a mouthwash for the prevention and treatment of gingivitis with on side effects

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References

(3) Aloe vera: It's effect on gingivitis by Ajmera N, Chatterjee A, Goyal V.(PubMed)
(4) A randomized, double-blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse by Chandrahas B, Jayakumar A, Naveen A, Butchibabu K, Reddy PK, Muralikrishna T.(PubMed)
(5) Effect of a dentifrice containing Aloe vera on plaque and gingivitis control. A double-blind clinical study in humans by de Oliveira SM, Torres TC, Pereira SL, Mota OM, Carlos MX.(PubMed)

Herbal Arnica on Wound Healing

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia. It has been used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.


The ingredients
Beside containing contain helenalin as it main ingredient used as an anti-inflammatory agent in herbal medicine, it also contains 11,13- dihydrohelenaline, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.

The Benefits
Homeopathic remedy (0712-2) from Arnica montana exerted wound closure potential in NIH 3T3 fibroblasts with low potency at a dilution of 1:100/in vitro with wound closure by 59.5%, but its homeopathic arnica preparation (D4), is found to be superior to diclofenac to reduce wound irritation. Topical Hypericum perforatum L. and Arnica montana L. In other studies were found to be effective on experimental wound healing on skin surgical incision induced on the back of Wistar rats.

C. Side effects
1. Arnica can increase leg pain in the short term
2. Allergy
Arnica used as Cosmetics and herbal remedies with Compositae plant extracts may cause an allergic effect in Compositae-allergic patients.
3. Atopic dermatitis
Patients with atopic dermatitis should use Arnica with care as the herb may increase the risk of a risk factor for Compositae allergy.
4. Toxicity
Arnica is toxic as it contains a measurable amount of helenalin.
5. Etc.


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References
1. The effect of topical arnica on muscle pain" by Adkison JD, Bauer DW, Chang T.(PubMed).
2. Cosmetics and herbal remedies with Compositae plant extracts - are they tolerated by Compositae-allergic patients?" by Paulsen E, Chistensen LP, Andersen KE.(PubMed)
(3) Contact allergy to Compositae plants in patients with atopic dermatitis. [Article in English, Serbian]" by Jovanović M, Poljacki M, Duran V, Vujanović L, Sente R, Stojanović S.,(PubMed)
(4) A homeopathic remedy from arnica, marigold, St. John's wort and comfrey accelerates in vitro wound scratch closure of NIH 3T3 fibroblasts by Hostanska K, Rostock M, Melzer J, Baumgartner S, Saller R.(PubMed)
(5) Efficacy of Arnica montana D4 for healing of wounds after Hallux valgus surgery compared to diclofenac by Karow JH, Abt HP, Fröhling M, Ackermann H.(PubMed)
(6) Effects of microcurrent application alone or in combination with topical Hypericum perforatum L. and Arnica montana L. on surgically induced wound healing in Wistar rats by Castro FC, Magre A, Cherpinski R, Zelante PM, Neves LM, Esquisatto MA, Mendonça FA, Santos GM.(PubMed)

Herbal Arctostaphylos uva-ursi on endometrial cancer

Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe. The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.

The endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to the menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of the uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.

The Ingredients It contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.

The benefits
Ursolic acid, a pentacyclic triterpene acid, extracted from bearberry is found to be effective in inhibition of the growth of endometrial cancer cell HEC108 line, in a dose- and time-dependent manner. As exposure of Ursolic acid decreased the anti-apoptotic Bcl-2 protein levels (a member of the Bcl-2 family of regulator proteins that regulate cell death) but increased Bax expression (upregulated by the tumor suppressor protein p53,)through a mitochondrial pathway, of that induced apoptosis of endometrial cancer HEC108 line. Other in the study of the same but within endometrial cancer SNG-II cells, ursolic acid strongly inhibited the growth of SNG-II cells in a dose- and time-dependent manner. The induced apoptotic processes in the endometrial cancer SNG-II cells is also involved in mitochondrial pathways and Bcl-2 family proteins.

The Side effect
1. Overdoses may cause gastrointestinal discomfort, including cause nausea, vomiting, etc. and fever, chills, severe back pain, ringing in the ears, etc.
2. The herb may interact with other medications, including a diuretic
3. Do not use the herb in newborn, children or if you are pregnant or breastfeeding without approval from the related field specialist.
4. Etc.


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References
(1) Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells by Achiwa Y, Hasegawa K, Udagawa Y.(PubMed)
(2) Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells by Achiwa Y, Hasegawa K, Komiya T, Udagawa Y.(PubMed)

How to Normalize Your Blood Cholesterol with No Side Effects

Scientists may have a functional herb in reducing the risk and treatment of abnormal blood cholesterol in the bloodstream with no side effects, some studies suggested.

Cholesterol is a waxy substance found in all cells in our body.

The waxy substance produced by the liver and or intake from the dietary sources plays a critical role in the production of sex hormone, the building block for the tissue and assistance of bile production in the liver for digestion.

There are 2 main types of cholesterol;
* The good cholesterol or high-density lipoproteins (HDL) which process the unique function in the transportation of cholesterol from the cells and tissue back to the liver. The good cholesterol also inhibits bad cholesterol over-accumulated in the cells.

* The Bad cholesterol or low-density lipoproteins (LDL) which process the function to deliver cholesterol to cells to build membranes, to the synthesis of steroid hormones.

An unhealthy diet with high in saturated and trans fats, red meat, processed foods and less in fruits and vegetables and lifestyle can cause high levels of LDL, leading to the development of serious health problems including clogged arteries, heart disease, and stroke.


In "YOUR GUIDE TO Lowering Your Cholesterol With TLC" published by the US. Department of Health and Human Services, the author wrote, "Studies have proven that lowering LDL can prevent heart attacks and reduce deaths from heart disease in both men and women". and "It can slow, stop, or even reverse the buildup of plaque. It also can lower the cholesterol content in unstable plaques, making them more stable and less likely to burst and cause a heart attack. Lowering LDL is especially important for those who already have heart disease or have had a heart attack—it will reduce the risk of another heart attack and can actually prolong life. The level to which your LDL must be lowered depends on the risk for heart disease or having a heart attack that you are found to have at the start of treatment".


These results suggested that by following a healthy diet pattern and lifestyle high levels of bad cholesterol can be reversed regardless of other factors.

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, It has been cultivated all over the world as hay for cattle feeding.

The leaves, sprouts, and seeds to make medicine has been used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance the digestive system, bleeding disorder, kidney, and urinary tract infection, etc.

North America aboriginal has used Alfalfa seed as food, such as making bread and mush.

In the study of Fifteen patients with hyperlipoproteinemia (HLP), types IIA (n = 8), IIB (n = 3) and IV (n = 4) given 40 g of heat prepared alfalfa seeds 3 times daily at mealtimes for 8 weeks with otherwise unchanged diet, researchers found that

* In patients with type II HLP alfalfa treatment caused after 8 weeks a maximal lowering of pretreatment median values of total plasma cholesterol from 9.58 to 8.00 mmol/l (P less than 0.001) and low density lipoprotein (LDL) cholesterol from 7.69 to 6.33 mmol/l (P less than 0.01), which corresponds to decreases of 17% and 18%, respectively.

* Maximal decrease in these patients was 26% in total cholesterol and 30% in LDL cholesterol.

* Apolipoprotein B decreased in the same period from 2.17 to 1.43 g/l (P less than 0.05) in type II HLP, corresponding to 34% decrease, whereas apolipoprotein A-I did not change.
These results suggested alfalfa seeds can be added to the diet to help normalize serum cholesterol concentrations in patients with type II HLP.

Furthermore, in the evaluation of the effect of an aqueous alfalfa extract (AAE) on production, performance, egg quality and lipid metabolism of laying hens between 28 and 36 weeks of age randomly assigned to Four groups, fed with diets containing 0, 0.05%, 0.1% and 0.15% AAE, researchers showed that

* In relation to the control group, cholesterol and triglycerides in yolk, liver, and serum and serum very-low-density lipoprotein cholesterol were lower in 0.15% AAE-treated birds at day 42 and day 56.

* It also significantly decreased activities of acetyl-CoA carboxylase (ACC) which has the function in regulating fatty acid synthesis and degradation, β-hydroxy-β-methylglutaryl-CoA (HMG CoA) reductase which has a function in controlling the metabolic pathway that produces cholesterol and other isoprenoids and fatty acid synthetase (FAS) at day 56.

These results indicated dietary AAE could be applied to improve eggshell quality and modify the lipid status of laying hens and eggs.

Interestingly, Dr. Yu CH, the lead author, in the study "[Study on the chemical constituents from the aerial parts of Medicago sativa and their hypolipidemic activity]" to isolated some chemical constituents from the aerial parts of Medicago sativa suggested the 2 new compounds soysaponin I (I), azukisaponin V (II) also process antihyperlipidemic activity..

Taken altogether, Herbal Alfalfa may be considered a function herb for the prevention and treatment of high blood cholesterol.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Alfalfa seeds lower low-density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinemia. by Mölgaard J, von Schenck H, Olsson AG. (PubMed)
(2) [Study on the chemical constituents from the aerial parts of Medicago sativa and their hypolipidemic activity].[Article in Chinese] by Yu CH, Liang DL, Guo JN, Mei QX, Yang DP. (PubMed)
(3) Effects of an aqueous alfalfa extract on production performance, egg quality and lipid metabolism of laying hens by Deng W, Dong XF, Tong JM, Xie TH, Zhang Q.(PubMed)

Tuesday, November 5, 2019

Arnica, a Potent Anti Edema and Bruising Herbal Medicine

Herbal Arnica may have a therapeutic and substantial effect in reduced progression and treatment of edema, some scientists suggested.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries in the treatment of strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.

Edema is a condition, characterized by excessive accumulation of fluids in some tissues within the body.

The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.


In the study to compare the efficacy of herbal Arnica and corticosteroids in reduced postoperative edema and bruising associated with rhinoplasty of 48 primary rhinoplasty patients randomized assigned to three groups as follow

* Group P received 10 mg of dexamethasone (intravenously) intraoperatively followed by a 6-day oral tapering dose of methyl-prednisone
* Group A received Arnica three times a day for 4 days, and
* Group C received neither agent and served as the control.

With 3 blinded panelists rated the extent of ecchymosis, the intensity of the ecchymosis, and the severity of the edema


After observing the study over the entire period, scientists postulated that
* There were no significant differences in all groups on the day 2 of postoperative
* In compared to increased swelling of the control group, both groups A and P demonstrated a significant improvement in edema rating.


Interestingly, the conventional medicine administration group exerted a higher intensity of ecchymosis compared to groups A and C on the day of postoperative and all groups displayed no difference in magnitude of edema.



However, between the period of days 2 and 8, groups A and C exhibited significantly more resolution of ecchymosis compared to group P.


The results suggested that although herbal Arnica may have a therapeutic property in reducing edema during the early postoperative period, the herbal medicine did not provide similar benefits in regard to the extent and intensity of ecchymosis in compared to corticosteroids.


In order to further confirmation of the effect of herbal Arnica in reduced postoperative ecchymosis and edema, researchers at the joint study lead University of Miami Miller School of Medicine, conducted an investigation in a select population of healthy volunteers after oculofacial surgery by examining the postoperative course and medical records of a total of 27 patients (16 females, 11 males) with age range was 18 to 70 years using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.


According to the result of the experiment, the application of Arnica 50 M (10) 50% and Ledum 50 M (10) pads bilaterally after surgery through postoperative day 6, showed a significantly accelerated healing from day 7 to day 12 in dose depending manner, without inflicting any adverse effects.

The findings suggested that the application of composited Arnica and Ledum displays a potential efficacy in reducing postoperative ecchymosis and edema after oculofacial surgery.


The above differentiation of herbal Arnica in improved edema after surgery were supported by the joint study lead by the Research Center of University of adult male Wistar rats inoculated with 1% carrageenan into the footpad to induce edema then treated with Arnica montana 6cH, dexamethasone (4.0 mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation.

According to the investigation, the application of the Arnica group exhibited anti-edema through increased lymphatic edema absorption, particularly, in late edema presented less intense edema treatment group after adjusting to the individually qualitative of inflammatory vascular events.



Moreover, the edema inhibition of Arnica was attributed to significant reduced mast cell degranulation and increased lymphatic vessel diameter and decreased the production of prostaglandins associated with the development of edema, caused by subcutaneous carrageenan injection in the induction of local inflammation.


Taken together, herbal Arnica may be considered as a functional food in reduced progression and for treatment of edema and ecchymosis.


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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) A randomized, controlled comparison between arnica and steroids in the management of postrhinoplasty ecchymosis and edema by Totonchi A1, Guyuron B.(PubMed)
(2) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(3) Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation Ana Paula Kawakami,1 Cesar Sato,1 Thayna Neves Cardoso,1 and Leoni Villano Bonamin(Hidawi)

Herbal Arctostaphylos uva-ursi, the Free Radicals Scavenger Functional Herb

Herbal Arctostaphylos uva-ursi may have a potential effect in reducing the risk and treatment of oxidative stress-related diseases, some studies suggested.

Oxidative stress is a production of the imbalance of the ratio of free radicals and antioxidants in the bost body.

The imbalance of the ratio of free radicals and antioxidant in the bost body can be caused either by the overproduction of free radicals or antioxidant enzymes are suppressed by the outside sources.

However, most outside sources that suppress the levels of antioxidant enzymes also play an important role in stimulating the overexpression of free radicals, such as chemical toxins

Free radicals are unstable atoms with the unpaired electron in the outer ring. Therefore, in order for them to become stable, free radical either donates or steals an electron from stable molecules, leading to a chain of reaction that facilitates the onset of oxidative stress.

The chain once starts, it can not stop until the electron on the outer ring is paired or inhibited by antioxidant.

Free radical has been known to cause oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospholipids, DNA and RNA.

Antioxidants are stable molecules found abundantly in fruits, vegetables, and herbal medicine.

If oxidative stress-related diseases are associated with the overproduction of free radicals, then long-term intake of a healthy diet high in fruits, vegetables and less in red meat and saturated and trans fat and processed foods can reduce the risk of the diseases in the healthy individuals.

Dr. Halliwell B, in the study to reaffirm the effect of healthy dietary patterns against the onset of oxidative stress said, " diet-derived antioxidants may be particularly important in protecting against these diseases" and

"The physiological relevance of these effects is uncertain, as is the optimal intake of most diet-derived antioxidants. In principle, these questions could be addressed by examining the effects of dietary composition and/or antioxidant supplementation upon parameters of oxidative damage in vivo".

Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.

The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.

The herbal plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.

In the examining the Dr. Bol'shakova IV, the lead author at the Emanuel Institute of Biochemical Physics claim, that Arctostaphylos uva.processes a significant antioxidant property in the inhibition of free radicals generation, researchers launched an investigation to evaluate the concentration of compound that inhibited cell growth by 50% (IC(50)) of a range of phytochemicals and plant extracts.

All selected extracts were differentiated according to the antioxidant and genoprotective effects under conditions of oxidative stress in U937 cells.

Two phytochemicals-resveratrol and citroflavan-3-ol isolated from the herbal Arctostaphylos uva-ursi demonstrated the highest IC50 value of 13.7 microg/mL, compared to the lowest at 9,400 microg/mL. of Echinacea.

Extract of herbal Arctostaphylos uva-ursi displayed a significant attenuation of the oxidative stress induced by the etoposide injection by inhibiting the expression of H2O2- and tBOOH-induced DNA damage.

These results reconfirmed the findings of Dr. Bol'shakova IV team that herbal Arctostaphylos uva-ursi as a non-nutrient dietary constituent may act as significant bioactive compounds in enhancing the antioxidants activity and stimulating the production of antioxidant enzymes if the herb is administrated in an animal model.



Moreover, Dr.Matsuda H the antioxidant team leader at the Kinki University, Osaka in the finding the natural compounds or whole food with potential antioxidant effects evaluated the inhibitory effect of 50% ethanol extracts obtained from the leaves of six Arctostaphylos plants (A. patula, A. viscida, A. canescens, A. Columbiana, A. nevadensis and A. uva-ursi) (Ericaceae).

Injection of the extracts of A. patula showed potent inhibition against tyrosinase, the enzyme that causes oxidation of the skin pigment.

Also, Arctostaphylos uva-ursi not only inhibited the production of melanin from dopachrome by autoxidation and but reduced the over exhibited SOD (superoxide dismutase, free radical)-like activity.


Additionally, Arctostaphylos uva-ursi processed a moderate absorbance in the UV-B area.

The results not only reaffirm the claim of Dr. Bol'shakova IV suggestion but also introduce a new herbal whitening medicine for the skin.

Taken all together, Herbal Arctostaphylos uva-ursi may be considered a functional food for the prevention and an adjunct therapy combine with primary medicine for the treatment of oxidative-related diseases.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Antioxidant properties of plant extracts].[Article in Russian] by Bol'shakova IV, Lozovskaia EL, Sapezhinskiĭ II. (PubMed)
(2) Modulatory effects of resveratrol, citroflavan-3-ol, and plant-derived extracts on oxidative stress in U937 cells by O'Brien NM, Carpenter R, O'Callaghan YC, O'Grady MN, Kerry JP. (PubMed)
(3) Studies of cuticle drugs from natural sources. IV. Inhibitory effects of some Arctostaphylos plants on melanin biosynthesis. by Matsuda H, Higashino M, Nakai Y, Iinuma M, Kubo M, Lang FA. (PubMed)

Artichoke Inhibits Hepatitis C Virus Against Liver Infection

Scientists may have found a natural remedy for the treatment of hepatitis C infection with no side effects, according to studies.

Hepatitis C infection is an inflammatory liver disease associated with viral hepatitis C. The viral infection has affected over a million Americans today according to the statistic.

Epidemiological studies suggested that persistent infection with the hepatitis C virus (HCV) is a major risk for the development of HCC, the fifth most common cancer, and the third most common cause for cancer death in the world.

Contaminated blood and fluids are the most common causes of hepatitis C virus (HCV) infection.

Hepatitis C induces liver cancer through many stages including
* The incubation period which lasts about 45 days after exposing to the virus.

* Acute hepatitis, the short-term illness may last about 6 months. Most people can get rid of the virus in this stage, particularly to those with the strong immune system.

* Chronic hepatitis C if you can not get rid of the virus in the acute stage, the immune system will adapt to the new change, leading to chronic liver inflammation by the hep C virus.

* Cirrhosis, the liver scar, normally is formed due to the progression of the inflammation. Cirrhosis can be developed over a period of 20 years, after initial exposure to the virus.

* Liver cancer, the death of liver cells due to overexpression of liver scars.

Dr. Gremion C, the lead scientist in the attempt to explain the risk hepatitis C and immune system, said, "While a persistent infection is generally associated with a weak CD4+ and CD8+ T cell response during the acute phase, there is no good explanation as to why this response is strong enough in 20% of acutely infected people such that they spontaneously resolve the infection".

The results strongly suggested that if you have a strong immune system, your risk of hepatitis C infection can be resolved naturally.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

Researchers on finding a natural ingredient for the treatment of hepatitis C which presently affects millions of people globally examined the traditional use of Egyptian artichoke (WEA) for the treatment of HCV-infection and complications.

Injection of water extract of a WEA plant decreased the HCV viral load below the detection level in 12 out of 15 patients. In other words, artichoke exerted strong anti-HCV infection, depending on the state of the severity of the disease.

Furthermore, the water extract normalized the levels of enzymes associated with liver function and damage.

Moreover, The total WEA extract at IC50 ∼ 20 μg ml(-1), inhibited abnormal expression of genes in patients with hepatitis C infection, involving in drug metabolism and synthesis of cholesterol, steroids, and other lipids (CYP2B6 (OH-BUP)) and the formation and breakdown (metabolism) of various molecules and chemicals within cells (CYP2C19 (5-OH-OME)).

WEA was found to be more effective in inhibiting hepatitis C infection compared to the Hepar SL Forte(®) due to the presence of sesquiterpenes versus the abundance of phenolic compounds of the Hepar SL Forte(®).

In chemicals analysis, grosheimol and cynaropicrin, isolated from the WEA showed the most inhibitory effect against HCV with half-maximal effective concentrations (EC50s) in the low micromolar range.

Both tested compounds inhibited HCV entry into target cells in both cell-free infections and cell-cell transmission.

Both compounds belong to the group of sesquiterpene lactones which are found in the WEA but not in the Hepar SL Forte(®).


The results clearly supported the use of WEA in traditional use for the treatment of liver viral infection and complications.

Taken altogether, herbal Artichoke may be considered a functional remedy for the prevention and treatment of HCV infection, pending to the confirmation of larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials by Elsebai MF1, Abass K2, Hakkola J3, Atawia AR4, Farag MA. (PubMed)
(2) Pan-genotypic Hepatitis C Virus Inhibition by Natural Products Derived from the Wild Egyptian Artichoke by Elsebai MF1, Koutsoudakis G2, Saludes V2, Pérez-Vilaró G2, Turpeinen A3, Mattila S3, Pirttilä AM4, Fontaine-Vive F5, Mehiri M5, Meyerhans A6, Diez. (PubMed)
(3) Hepatitis C virus and the immune system: a concise review by Gremion C1, Cerny A. (PubMed)