Aero digestive tract is the combined organs and tissues of the respiratory tract and the upper part of the digestive tract including the lip, tongue, major salivary glands, gums and adjacent oral cavity tissues, floor of the mouth, tonsils, oropharynx, nasopharynx, hypopharynx and other oral regions, nasal cavity, accessory sinuses, middle ear, and larynx.
Cancer is a class of diseases characterized by irregular cell growth in the tissue of a specific organ due to the alternation of cell DNA.
The upper aerodigestive tract cancer a type of invasive cancer that starts in the cell on the surface of the inner lining of the aerodigestive tract before proliferating to a deeper layer to form a tumor.
According to the statistics provided by the Scottish Health Service, upper aerodigestive tract cancer accounts for approximately 4% of all malignancies with cancers of salivary glands, gums, nasopharynx, and nasal cavity and accessory sinuses. Epidermoid carcinomas account for greater than 95% of all cases.
Epidemiologically, aging, male gender, ethnicity are some of the most common prevalent factors associated with the incidences.
The 5-year relative survival rate of the upper aerodigestive tract (UADT) was approximately 50%, depending on the type of UADT.
Dr. F. Bravi, the lead scientist in the examination of the diet patterns in the risk of UADT wrote, "
The most consistent findings are the beneficial role of a dietary pattern based on fruit and vegetables or nutrients mostly contained in such foods, and the unfavorable role of an alcohol drinker pattern. A possible unfavorable role of patterns based on meats and animal products emerged as well".
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potent compound for the prevention and treatment of gastrointestinal tract cancer, researchers examined the effect of total allium, garlic, and onion intake on the risk of cancer of the upper aerodigestive tract (UADT).
The study identified 21 case-control and four cohort studies through the searching data of published observational studies, using a meta-analytic approach and random-effects models.
* The overall relative risks (RR) for the squamous cell carcinoma of the UADT were 0.72 (95% CI 0.57-0.91) for onion for the highest versus the lowest consumption.
* Onion showed a strong inverse relation in case-control studies with the RR of 0.56.
* In Chinese studies onion showed a lesser effect compared to garlic for esophageal than for head and neck cancers.
* Believe it or not, there was no relation between allium vegetable intake and adenocarcinoma of the esophagus.
These results strongly suggested that onion process a significant anti-upper aerodigestive tract (UADT) cancer effect, depending on the types of gastrointestinal tract cancer.
Collectively, researchers after taking other factors into account wrote, "We found a moderate inverse association between allium vegetable intake and the risk of squamous cell carcinoma of the UADT in case-control studies".
Taken altogether, onion processed a higher mount of onion A (ONA) may be considered a remedy for the treatment of upper aerodigestive tract cancer effect, depending on the types of UADT, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Allium vegetables and upper aerodigestive tract cancers: a meta-analysis of observational studies by Guercio V1, Turati F2, La Vecchia C1, Galeone C2, Tavani A. (PubMed)
(2) In vitro influence of spices and spice-active principles on digestive enzymes of rat pancreas and small intestine by Ramakrishna Rao R1, Platel K, Srinivasan K. (PubMed)
(3) Upper aerodigestive tract cancers by Muir C1, Weiland L. (PubMed)
(4) Dietary patterns and upper aerodigestive tract cancers: an overview and review by
Bravi V. Edefonti G. Randi M. Ferraroni C. La Vecchia A. Decarli (Annuals of Oncology)
Wednesday, November 13, 2019
Herbal Arctostaphylos uva-ursi, the Potential Anti Gastric/ Stomach Cancer Remedy
Scientists may have found a herbal remedy for the prevention and treatment of gastric cancer with no side effects, according to studies.
Gastric cancer or stomach cancer is a condition characterized by the abnormal growth of cells in the stomach tissue.
Most cases of gastric cancer start in the cells on the surface of the inner lining of the stomach tissue.
At stage 0, due to the gastric cancer cells was restricted or completely contained within the innermost layer of the lining, patients may not experience any symptoms.
However, at the later stage, the cancer cells can travel a distance away from the stomach to infect other tissue and organ, leading to secondary metastasis. If the tumor grows large enough, it may suppress the nearby blood vessels and nerve cells, causing blood leaked into the stomach and localized severe pain.
Besides common symptoms of cancers, patients with gastric cancer also experience some specific symptoms such as persistent abdominal (belly) pain., vague discomfort in the abdomen, a sense of fullness in the upper abdomen after eating a small meal and heartburn or indigestion.
If you are having some of the above symptoms, please check with your doctor to rule out the gastric cancer possibility.
Although there are many risk factors involved in the onset of the disease, such as family history, Helicobacter pylori infection, smoking, genetic preposition, certain stomach conditions, previous stomach surgery and type A blood, some researchers suggested that most common cause of gastric cancer in the Western world is the Western diet-related disease.
Dr. Bertuccio P, the lead scientist at the Istituto di Ricerche Farmacologiche Mario Negri, in the concern of diet pattern in the risk of gastric cancer wrote, " An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89)" and "A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category".
The results strongly indicated the risk of gastric cancer is substantially higher in the Western diet group compared to the lower risk of a healthy diet.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb plant has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.
The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
With an aim to find a natural ingredient or whole food for the treatment of gastric cancer, researchers at the Shanghai University of Traditional Chinese Medicine examined the effects of ursolic acid isolated from bearberry (Arctostaphylos uva-ursi) against the pathogenesis of gastric cancer characterized by excessive proliferation, abnormal differentiation, and reduced apoptosis.
Ursolic acid, extracted from traditional Chinese medicine bearberry, inhibited gastric cancer cell proliferation and induced apoptosis.
Further assessment of anti-gastric cancer, researchers discovered that ursolic acid exhibited apoptotic activity through cancer cell degradation observed in the gastric cancer BGC-823 cells.
In other words, the efficacy is associated with a translocation of cofilin-1 protein that activates the function of cytochrome c in program cell death from the mitochondria to the cytoplasm.
These results suggested that ursolic acid activated the function of proteins (the caspase cascade) associated with the cell death and apoptotic pathway.
Where Mitochondria are the major organelles involved in the biochemical execution of apoptosis
Dr. the lead scientist, after taking into account co and confounders said, "mitochondrial translocation of cofilin-1 might play a crucial role in the promotion of apoptosis and might be a key target for future treatment of human gastric cancer".
Taken altogether, Bearberry (herbal Arctostaphylos uva-ursi) processed a major compound of ursolic acid may be considered a functional remedy for the prevention and combined with other primary medicine for the treatment of gastric cancer, pending to the confirmation of large sample size and multicenter human study.
However, intake of ursolic acid as a supplement should be taken with extreme care to prevent overdoses in acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid by Tang Q, Ji Q, Tang Y, Chen T, Pan G, Hu S, Bao Y, Peng W, Yin P.(PubMed)
(2) Dietary patterns and gastric cancer risk: a systematic review and meta-analysis by Bertuccio P1, Rosato V, Andreano A, Ferraroni M, Decarli A, Edefonti V, La Vecchia C. (PubMed)
Gastric cancer or stomach cancer is a condition characterized by the abnormal growth of cells in the stomach tissue.
Most cases of gastric cancer start in the cells on the surface of the inner lining of the stomach tissue.
At stage 0, due to the gastric cancer cells was restricted or completely contained within the innermost layer of the lining, patients may not experience any symptoms.
However, at the later stage, the cancer cells can travel a distance away from the stomach to infect other tissue and organ, leading to secondary metastasis. If the tumor grows large enough, it may suppress the nearby blood vessels and nerve cells, causing blood leaked into the stomach and localized severe pain.
Besides common symptoms of cancers, patients with gastric cancer also experience some specific symptoms such as persistent abdominal (belly) pain., vague discomfort in the abdomen, a sense of fullness in the upper abdomen after eating a small meal and heartburn or indigestion.
If you are having some of the above symptoms, please check with your doctor to rule out the gastric cancer possibility.
Although there are many risk factors involved in the onset of the disease, such as family history, Helicobacter pylori infection, smoking, genetic preposition, certain stomach conditions, previous stomach surgery and type A blood, some researchers suggested that most common cause of gastric cancer in the Western world is the Western diet-related disease.
Dr. Bertuccio P, the lead scientist at the Istituto di Ricerche Farmacologiche Mario Negri, in the concern of diet pattern in the risk of gastric cancer wrote, " An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89)" and "A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category".
The results strongly indicated the risk of gastric cancer is substantially higher in the Western diet group compared to the lower risk of a healthy diet.
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb plant has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.
The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
With an aim to find a natural ingredient or whole food for the treatment of gastric cancer, researchers at the Shanghai University of Traditional Chinese Medicine examined the effects of ursolic acid isolated from bearberry (Arctostaphylos uva-ursi) against the pathogenesis of gastric cancer characterized by excessive proliferation, abnormal differentiation, and reduced apoptosis.
Ursolic acid, extracted from traditional Chinese medicine bearberry, inhibited gastric cancer cell proliferation and induced apoptosis.
Further assessment of anti-gastric cancer, researchers discovered that ursolic acid exhibited apoptotic activity through cancer cell degradation observed in the gastric cancer BGC-823 cells.
In other words, the efficacy is associated with a translocation of cofilin-1 protein that activates the function of cytochrome c in program cell death from the mitochondria to the cytoplasm.
These results suggested that ursolic acid activated the function of proteins (the caspase cascade) associated with the cell death and apoptotic pathway.
Where Mitochondria are the major organelles involved in the biochemical execution of apoptosis
Dr. the lead scientist, after taking into account co and confounders said, "mitochondrial translocation of cofilin-1 might play a crucial role in the promotion of apoptosis and might be a key target for future treatment of human gastric cancer".
Taken altogether, Bearberry (herbal Arctostaphylos uva-ursi) processed a major compound of ursolic acid may be considered a functional remedy for the prevention and combined with other primary medicine for the treatment of gastric cancer, pending to the confirmation of large sample size and multicenter human study.
However, intake of ursolic acid as a supplement should be taken with extreme care to prevent overdoses in acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Mitochondrial translocation of cofilin-1 promotes apoptosis of gastric cancer BGC-823 cells induced by ursolic acid by Tang Q, Ji Q, Tang Y, Chen T, Pan G, Hu S, Bao Y, Peng W, Yin P.(PubMed)
(2) Dietary patterns and gastric cancer risk: a systematic review and meta-analysis by Bertuccio P1, Rosato V, Andreano A, Ferraroni M, Decarli A, Edefonti V, La Vecchia C. (PubMed)
Lycopene Protects the Lung Against Cancer Developing
The lung is a vital organ located near the backbone on either side of the heart with major functions to inhale oxygen from the air to the bloodstream that nourishes the body cells and exhale carbon dioxide from the bloodstream.
Other functions of the lung are to maintain the right levels of pH, filter out blood clots, protect the heart against shock, infection, and speech.
Cancer is a class of diseases caused by cell growth and multiplication disorderly and uncontrollably due to the alternation of the DNA.
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. A most common form of primary lung cancer is derived from epithelial cells.
According to the statistics provided by the American Lung Cancer Association, lung cancer is the leading cancer killer in both men and women in the U.S. in 2018, 154,050 Americans died from lung cancer in 2018, accounting for approximately 25 percent of all cancer deaths.
The exact causes of lung cancer are unknown. However, passive smoking, tobacco smoking are 2 of the most common risk factors were found in patients with the disease.
Dr. wrote, "Tobacco smoking remains the most established cause of lung carcinogenesis and other disease processes. Over the last 50 years, tobacco refinement and the introduction of filters have brought a change in histology, and now adenocarcinoma has become the most prevalent subtype".
And, "Over the last decade, smoking also has emerged as a strong prognostic and predictive patient characteristic along with other variables:.
Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the treatment of cancer, researchers examined the protective effects of tomato lycopene against the formation and the development of lung cancer.
According to the tested analysis, lycopene inhibited the growth of several cultured lung cancer cells and prevent lung tumorigenesis in animal models through various mechanisms.
More precisely, lycopene efficacy in the prevention and treatment of lung cancer by promoting the balanced ratio of free radicals and antioxidant enzymes produced by the host.
Lycopene exerted cell cycle arrest and/or apoptotic activity by regulating abnormal growth factor signaling, and inhibiting the changes in cell growth-related enzymes.
Smoke-induced inflammation-induced abnormal cell growth associated with the risk of lung cancer also inhibited by the application of lycopene.
Lycopene also inhibited the lung cancer invasion, angiogenesis, and metastasis in the tested animal model through its metabolites.
Based on the findings, researchers said, "The study reviews data on the cancer-preventive activities of lycopene, possible mechanisms involved, and the relationship between lycopene consumption and human cancer risk." and " More well-controlled clinical intervention trials are needed to further clarify the exact role of lycopene in the prevention of lung cancer cell growth".
Taken altogether, lycopene found in tomato combined with conventional medicine may be considered an anti lung cancer remedy, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation by Aizawa K1,2, Liu C1, Tang S1, Veeramachaneni S1, Hu KQ1, Smith DE3, Wang XD. (PubMed)
(2) Tomato lycopene and lung cancer prevention: from experimental to human studies by Palozza P1, Simone RE, Catalano A, Mele MC. (PubMed)
(3) Tobacco Smoking and Lung Cancer. Perception-changing facts by Muhammad Furrukh. (PMC)
Other functions of the lung are to maintain the right levels of pH, filter out blood clots, protect the heart against shock, infection, and speech.
Cancer is a class of diseases caused by cell growth and multiplication disorderly and uncontrollably due to the alternation of the DNA.
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. A most common form of primary lung cancer is derived from epithelial cells.
According to the statistics provided by the American Lung Cancer Association, lung cancer is the leading cancer killer in both men and women in the U.S. in 2018, 154,050 Americans died from lung cancer in 2018, accounting for approximately 25 percent of all cancer deaths.
The exact causes of lung cancer are unknown. However, passive smoking, tobacco smoking are 2 of the most common risk factors were found in patients with the disease.
Dr. wrote, "Tobacco smoking remains the most established cause of lung carcinogenesis and other disease processes. Over the last 50 years, tobacco refinement and the introduction of filters have brought a change in histology, and now adenocarcinoma has become the most prevalent subtype".
And, "Over the last decade, smoking also has emerged as a strong prognostic and predictive patient characteristic along with other variables:.
Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
On finding a potential compound for the treatment of cancer, researchers examined the protective effects of tomato lycopene against the formation and the development of lung cancer.
According to the tested analysis, lycopene inhibited the growth of several cultured lung cancer cells and prevent lung tumorigenesis in animal models through various mechanisms.
More precisely, lycopene efficacy in the prevention and treatment of lung cancer by promoting the balanced ratio of free radicals and antioxidant enzymes produced by the host.
Lycopene exerted cell cycle arrest and/or apoptotic activity by regulating abnormal growth factor signaling, and inhibiting the changes in cell growth-related enzymes.
Smoke-induced inflammation-induced abnormal cell growth associated with the risk of lung cancer also inhibited by the application of lycopene.
Lycopene also inhibited the lung cancer invasion, angiogenesis, and metastasis in the tested animal model through its metabolites.
Based on the findings, researchers said, "The study reviews data on the cancer-preventive activities of lycopene, possible mechanisms involved, and the relationship between lycopene consumption and human cancer risk." and " More well-controlled clinical intervention trials are needed to further clarify the exact role of lycopene in the prevention of lung cancer cell growth".
Taken altogether, lycopene found in tomato combined with conventional medicine may be considered an anti lung cancer remedy, pending on the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation by Aizawa K1,2, Liu C1, Tang S1, Veeramachaneni S1, Hu KQ1, Smith DE3, Wang XD. (PubMed)
(2) Tomato lycopene and lung cancer prevention: from experimental to human studies by Palozza P1, Simone RE, Catalano A, Mele MC. (PubMed)
(3) Tobacco Smoking and Lung Cancer. Perception-changing facts by Muhammad Furrukh. (PMC)
Bromelain, the Potential and Natural Treatment of Arthritis with No Side Effects
Arthritis is a class of disease associated with the inflammation of one or more of your joints, including rheumatoid arthritis.
Most common symptoms of arthritis are joint pain and stiffness.
According to the statistics provided by the Arthritis Foundation, in the US, approximately, 54 million adults have doctor-diagnosed arthritis accompanied by 300,000 babies and children.
The most common type of arthritis is osteoarthritis which affects over 30 million Americans. Believe it or not, by 2040, the number of people with arthritis will be increased to more than 78 million.
Epidemiologically, certain factors such as family history with some types of arthritis, age, gender, a previous joint injury that was not treated properly can contribute to the risk of the disease.
However, some researchers suggested that widespread obesity in the US may be one of the important features that increase the prevalence of arthritis.
Dr. Lauren K. King wrote, "Obesity is associated with the incidence and progression of OA of both weight-bearing and non-weight-bearing joints, to rate of joint replacements as well as operative complications".
And, "Weight loss in OA can impart clinically significant improvements in pain and delay the progression of joint structural damage. Further work is required to determine the relative contributions of mechanical and metabolic factors in the pathogenesis of OA.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for diseases associated with inflammation, researchers investigated the efficacy of long-term prophylactic enzyme therapy and combination therapy with cyclosporin in an animal model.
Selected rats with collagen-induced arthritis were divided into administration of the following drugs: cyclosporin A (5 mg/kg/day and 10 mg/kg/day orally); a mixture of enzymes containing pure substances (bromelain, trypsin, rutin) in the same ratio as in Phlogenzym (PHL, 150 mg/kg, twice daily intrarectally); and a combination of 5 mg/kg/day cyclosporin A plus 300 mg/kg/day PHL for a period of 50 days from the immunization.
According to the tested assays, a mixture of enzymes containing pure substances (bromelain, trypsin, rutin showed a similar effect in significant inhibition of both inflammation and destructive arthritis-associated changes compared to the treatment with 10 mg/kg cyclosporin A, and combination therapy with half dosages of cyclosporin A (5 mg/kg) plus PHL.
However, PHL alone reduced the disease markers to a lesser extent compared to the enzyme therapy which exerts a similar effect but at a later stage of arthritis development.
Based on the findings, researchers at the Research Institute of Rheumatic Diseases said, "Our results show the inhibitory effect of enzyme therapy on collagen-induced arthritis in rats, as well as the efficacy of cyclosporin A given in low doses in combination with enzyme therapy, which may be useful in the treatment of rheumatoid arthritis".
In order to find more information about bromelain anti-arthritis activity, researchers at the same institute examined the results in rats with adjuvant-induced arthritis administered either cyclosporin A (2.5 or 5.0 mg/kg/day per os), a mixture of enzymes (Phlogenzym (PHL); 45 mg/kg twice daily intrarectally), or a combination of 2.5 mg cyclosporin A and 90 mg PHL for a period of 40 days from the adjuvant application.
Combination therapy with cyclosporin A plus PH significantly inhibited both the inflammation and destructive arthritis-associated changes similar to that of 5 mg of cyclosporin A.
PHL administrated alone also inhibited all arthritic markers to a lesser extent and at a later stage of arthritis development similar to the treatment of 2.5 mg of cyclosporin A.
Dr. Rovenská E, after taking into account of co and confounder wrote, "The results show the inhibitory effect of enzyme therapy on rat adjuvant arthritis, as well as the efficacy of a low dose of cyclosporin A given in combination with enzyme therapy, which may be useful in the treatment of rheumatoid arthritis".
Taken altogether, bromelain used alone or combined with other herbal medicines may be considered supplements for the treatment of arthritis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibitory effect of enzyme therapy and combination therapy with cyclosporin A on collagen-induced arthritis by Rovenská E1, Svík K, Stancíková M, Rovenský J. (PubMed)
(2) Enzyme and combination therapy with cyclosporin A in the rat developing adjuvant arthritis by Rovenská E1, Svík K, Stancíková M, Rovenský J. (PubMed)
(3) Obesity & osteoarthritis by Lauren K. King,* Lyn March,** and Ananthila Anandacoomarasamy. (PMC)
Most common symptoms of arthritis are joint pain and stiffness.
According to the statistics provided by the Arthritis Foundation, in the US, approximately, 54 million adults have doctor-diagnosed arthritis accompanied by 300,000 babies and children.
The most common type of arthritis is osteoarthritis which affects over 30 million Americans. Believe it or not, by 2040, the number of people with arthritis will be increased to more than 78 million.
Epidemiologically, certain factors such as family history with some types of arthritis, age, gender, a previous joint injury that was not treated properly can contribute to the risk of the disease.
However, some researchers suggested that widespread obesity in the US may be one of the important features that increase the prevalence of arthritis.
Dr. Lauren K. King wrote, "Obesity is associated with the incidence and progression of OA of both weight-bearing and non-weight-bearing joints, to rate of joint replacements as well as operative complications".
And, "Weight loss in OA can impart clinically significant improvements in pain and delay the progression of joint structural damage. Further work is required to determine the relative contributions of mechanical and metabolic factors in the pathogenesis of OA.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for diseases associated with inflammation, researchers investigated the efficacy of long-term prophylactic enzyme therapy and combination therapy with cyclosporin in an animal model.
Selected rats with collagen-induced arthritis were divided into administration of the following drugs: cyclosporin A (5 mg/kg/day and 10 mg/kg/day orally); a mixture of enzymes containing pure substances (bromelain, trypsin, rutin) in the same ratio as in Phlogenzym (PHL, 150 mg/kg, twice daily intrarectally); and a combination of 5 mg/kg/day cyclosporin A plus 300 mg/kg/day PHL for a period of 50 days from the immunization.
According to the tested assays, a mixture of enzymes containing pure substances (bromelain, trypsin, rutin showed a similar effect in significant inhibition of both inflammation and destructive arthritis-associated changes compared to the treatment with 10 mg/kg cyclosporin A, and combination therapy with half dosages of cyclosporin A (5 mg/kg) plus PHL.
However, PHL alone reduced the disease markers to a lesser extent compared to the enzyme therapy which exerts a similar effect but at a later stage of arthritis development.
Based on the findings, researchers at the Research Institute of Rheumatic Diseases said, "Our results show the inhibitory effect of enzyme therapy on collagen-induced arthritis in rats, as well as the efficacy of cyclosporin A given in low doses in combination with enzyme therapy, which may be useful in the treatment of rheumatoid arthritis".
In order to find more information about bromelain anti-arthritis activity, researchers at the same institute examined the results in rats with adjuvant-induced arthritis administered either cyclosporin A (2.5 or 5.0 mg/kg/day per os), a mixture of enzymes (Phlogenzym (PHL); 45 mg/kg twice daily intrarectally), or a combination of 2.5 mg cyclosporin A and 90 mg PHL for a period of 40 days from the adjuvant application.
Combination therapy with cyclosporin A plus PH significantly inhibited both the inflammation and destructive arthritis-associated changes similar to that of 5 mg of cyclosporin A.
PHL administrated alone also inhibited all arthritic markers to a lesser extent and at a later stage of arthritis development similar to the treatment of 2.5 mg of cyclosporin A.
Dr. Rovenská E, after taking into account of co and confounder wrote, "The results show the inhibitory effect of enzyme therapy on rat adjuvant arthritis, as well as the efficacy of a low dose of cyclosporin A given in combination with enzyme therapy, which may be useful in the treatment of rheumatoid arthritis".
Taken altogether, bromelain used alone or combined with other herbal medicines may be considered supplements for the treatment of arthritis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibitory effect of enzyme therapy and combination therapy with cyclosporin A on collagen-induced arthritis by Rovenská E1, Svík K, Stancíková M, Rovenský J. (PubMed)
(2) Enzyme and combination therapy with cyclosporin A in the rat developing adjuvant arthritis by Rovenská E1, Svík K, Stancíková M, Rovenský J. (PubMed)
(3) Obesity & osteoarthritis by Lauren K. King,* Lyn March,** and Ananthila Anandacoomarasamy. (PMC)
Tuesday, November 12, 2019
Herbal Coltsfoot(Tussilago farfara) Anti Bacterial and Cancer Remedy
Cancer is a group of cell mutated diseases caused by the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining of the tissue of an organ. At the early, most people with cancer are asymptomatic, however, at the later, due to the size and the tumor, patients may experience the general cancer symptoms such as unintended weight loss, fatigue, gastrointestinal discomfort and loss of appetite and localized symptoms such as severe pain and bleeding.
The exact causes of cancer are not identified. As of today, researchers do not know why one person develops cancer and another doesn’t, even they share some common risk factors of the disease.
However, most prevalent factors associated with the cancer onset are age, family history, long-term exposure to certain cancer-induced chemicals, use of tobacco and excessive alcohol drinking,..... the list goes on and on, depending on the types of cancer.
Some researchers suggested that the causes of cancer in the Western world may be associated with widespread obesity.
Dr. Karen Basen-Engquist, in the evaluation of obesity risk of cancer, said, "In the United States, approximately 85,000 new cancer cases per year are related to obesity. Recent research has found that as the body mass index increases by 5 kg/m2, cancer mortality increases by 10%".
And, "High priorities for future research involve additional work on the underlying mechanisms, and trials to examine the effect of lifestyle behavior change and weight loss interventions on cancer and intermediate biomarkers".
The findings strong indicated the risk of cancer is increased substantially in obese.
Bacteria are single-celled organisms of which only a few have been found to cause infection.
The bacterial infection is the infection caused by bacteria. Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has made many of them resistant to antibiotics.
There are trillions of strains of bacteria in the world, but only a few of these cause diseases in humans. Some of them live inside our gut.
Most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.
In severe cases, the patient may also experience symptoms of swollen lymph glands.
Most cases of bacterial infection can be treated successfully if the types of bacteria that cause the infection are identified.
There are many risk factors associated with the onset of bacterial infection, some researchers suggested that people with a weakened immune system may increase the prevalence of bacterial infection.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of chronic disease, researchers examined the anti-bacterial and cancer effects of sesquiterpenoids from the flower bud extract of Tussilago farfara by the silver and gold nanoparticles that had a characteristic surface plasmon resonance at 416 nm and 538 nm, respectively.
According to the tested analysis, the silver nanoparticles showed better antibacterial activity (two- to four-fold enhancement) on both Gram-positive and Gram-negative bacteria compared to the extract alone.
Furthermore, the highest antibacterial activity was obtained against vancomycin-resistant Enterococci Van-A type Enterococcus faecium.
Gold nanoparticles exerted the highest cytotoxicity against cancer cell lines, compared silver nanoparticles, particularly in human pancreas ductal adenocarcinoma cells.
Based on the findings, researchers said, "both nanoparticles synthesized with the sesquiterpenoids from T. farfara flower bud extract can be applied as drug delivery vehicles of anticancer or antibacterial agents for future nanomedicine applications.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of bacterial infection and cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sesquiterpenoids from Tussilago farfara Flower Bud Extract for the Eco-Friendly Synthesis of Silver and Gold Nanoparticles Possessing Antibacterial and Anticancer Activities by Lee YJ1, Song K2, Cha SH3, Cho S4, Kim YS5, Park Y. (PubMed)
Most cases of cancer begin in the cells on the surface of the inner lining of the tissue of an organ. At the early, most people with cancer are asymptomatic, however, at the later, due to the size and the tumor, patients may experience the general cancer symptoms such as unintended weight loss, fatigue, gastrointestinal discomfort and loss of appetite and localized symptoms such as severe pain and bleeding.
The exact causes of cancer are not identified. As of today, researchers do not know why one person develops cancer and another doesn’t, even they share some common risk factors of the disease.
However, most prevalent factors associated with the cancer onset are age, family history, long-term exposure to certain cancer-induced chemicals, use of tobacco and excessive alcohol drinking,..... the list goes on and on, depending on the types of cancer.
Some researchers suggested that the causes of cancer in the Western world may be associated with widespread obesity.
Dr. Karen Basen-Engquist, in the evaluation of obesity risk of cancer, said, "In the United States, approximately 85,000 new cancer cases per year are related to obesity. Recent research has found that as the body mass index increases by 5 kg/m2, cancer mortality increases by 10%".
And, "High priorities for future research involve additional work on the underlying mechanisms, and trials to examine the effect of lifestyle behavior change and weight loss interventions on cancer and intermediate biomarkers".
The findings strong indicated the risk of cancer is increased substantially in obese.
Bacteria are single-celled organisms of which only a few have been found to cause infection.
The bacterial infection is the infection caused by bacteria. Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has made many of them resistant to antibiotics.
There are trillions of strains of bacteria in the world, but only a few of these cause diseases in humans. Some of them live inside our gut.
Most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.
In severe cases, the patient may also experience symptoms of swollen lymph glands.
Most cases of bacterial infection can be treated successfully if the types of bacteria that cause the infection are identified.
There are many risk factors associated with the onset of bacterial infection, some researchers suggested that people with a weakened immune system may increase the prevalence of bacterial infection.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of chronic disease, researchers examined the anti-bacterial and cancer effects of sesquiterpenoids from the flower bud extract of Tussilago farfara by the silver and gold nanoparticles that had a characteristic surface plasmon resonance at 416 nm and 538 nm, respectively.
According to the tested analysis, the silver nanoparticles showed better antibacterial activity (two- to four-fold enhancement) on both Gram-positive and Gram-negative bacteria compared to the extract alone.
Furthermore, the highest antibacterial activity was obtained against vancomycin-resistant Enterococci Van-A type Enterococcus faecium.
Gold nanoparticles exerted the highest cytotoxicity against cancer cell lines, compared silver nanoparticles, particularly in human pancreas ductal adenocarcinoma cells.
Based on the findings, researchers said, "both nanoparticles synthesized with the sesquiterpenoids from T. farfara flower bud extract can be applied as drug delivery vehicles of anticancer or antibacterial agents for future nanomedicine applications.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of bacterial infection and cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sesquiterpenoids from Tussilago farfara Flower Bud Extract for the Eco-Friendly Synthesis of Silver and Gold Nanoparticles Possessing Antibacterial and Anticancer Activities by Lee YJ1, Song K2, Cha SH3, Cho S4, Kim YS5, Park Y. (PubMed)
Carotenoids in Different Etiologies of Chronic Liver Diseases
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.
Most common types of liver disease in the US are
* Hepatitis C (26%) is a liver disease caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
* Alcoholic liver disease (21%) is a condition that caused long-term excessive alcohol drinking. It is known that years of alcohol abuse can cause the liver to become inflamed and swollen. Over time, it has been found to induce the formation of liver scars, known as cirrhosis. Cirrhosis is the final stage of liver disease.
* Hepatitis C plus alcoholic liver disease (15%)
* Cryptogenic causes (18%) is a condition with no apparent underlying reason. However, most researchers suggested that many cases of cryptogenic cirrhosis are likely caused by non-alcoholic fatty liver disease (NAFLD), a condition of fat accumulated in the liver.
* Hepatitis B and D (15%) are liver diseases caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
Most common symptoms of liver disease are jaundice, abdominal pain and swelling, swelling in the legs and ankles, itchy skin, dark urine color, pale stool color, or bloody or tar-colored stool, chronic fatigue and nausea or vomiting.
Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a natural ingredient for the treatment of chronic liver diseases, researchers examined the effects of carotenoids against reactive oxygen species and oxidative damage associated with the onset of liver damage.
Overexpression of free radical-induced oxidative stress in the liver not only induced lipid and protein oxidation but also caused the alternation of the liver cell DNA, leading to reduced function of the liver.
Dietary carotenoids as antioxidants not only protected the liver cellular metabolism but also balanced the ratio of free radical in the liver, thus preventing the onset of liver oxidative stress, the major cause of chronic liver disease, including cancer.
In other words, carotenoids enhanced the liver functioning by inactivating reactive oxygen species and obstructing lipid and protein oxidative damage, the vital prophylactic strategic molecules.
In chemical differentiation,
* β-Carotene supplementation enhanced the levels of antioxidants in the tested subject that act as free radical scavengers such as vitamin C, glutathione, and glutathione-related enzymes against liver toxicity caused by administration of aflatoxin-B1.
Furthermore, β-Carotene also inhibited liver disease associated with both HBV and HCV by suppressing the elevation of inflammatory and oxidative conditions in hepatocytes.
* Lycopene found abundantly in tomato and products of tomato possesses antioxidant, and detoxification abilities in many epidemiological and animal studies, thus preventing liver oxidative stress-induced chronic diseases.
* Lutein, another phytochemical and bioactive compound found in carotenoids has been found epidemiologically to possess a strong antioxidant activity by promoting the production liver antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione, against diseases associated with oxidative stress including antiviral activity against hepatitis B.
* Other carotenoids such as β-Cryptoxanthin, α-carotene, fucoxanthin, and zeaxanthin also show promising effects against chronic liver injury through their antioxidant activity.
Taken altogether, betacyanins used alone or combined with conventional medicine may be considered a remedy for the prevention and treatment of adjuvant rheumatic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination,
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Role of Dietary Carotenoids in Different Etiologies of Chronic Liver Diseases By Uzma Latief and Riaz Ahmad
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reducing partly or completely the function of the liver, including liver failure.
Most common types of liver disease in the US are
* Hepatitis C (26%) is a liver disease caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
* Alcoholic liver disease (21%) is a condition that caused long-term excessive alcohol drinking. It is known that years of alcohol abuse can cause the liver to become inflamed and swollen. Over time, it has been found to induce the formation of liver scars, known as cirrhosis. Cirrhosis is the final stage of liver disease.
* Hepatitis C plus alcoholic liver disease (15%)
* Cryptogenic causes (18%) is a condition with no apparent underlying reason. However, most researchers suggested that many cases of cryptogenic cirrhosis are likely caused by non-alcoholic fatty liver disease (NAFLD), a condition of fat accumulated in the liver.
* Hepatitis B and D (15%) are liver diseases caused by liver inflammation caused by viral Hepatitis C, leading to irreversible liver scars. Over time, the condition can also induce liver cancer.
Most common symptoms of liver disease are jaundice, abdominal pain and swelling, swelling in the legs and ankles, itchy skin, dark urine color, pale stool color, or bloody or tar-colored stool, chronic fatigue and nausea or vomiting.
Carotenoids are a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a natural ingredient for the treatment of chronic liver diseases, researchers examined the effects of carotenoids against reactive oxygen species and oxidative damage associated with the onset of liver damage.
Overexpression of free radical-induced oxidative stress in the liver not only induced lipid and protein oxidation but also caused the alternation of the liver cell DNA, leading to reduced function of the liver.
Dietary carotenoids as antioxidants not only protected the liver cellular metabolism but also balanced the ratio of free radical in the liver, thus preventing the onset of liver oxidative stress, the major cause of chronic liver disease, including cancer.
In other words, carotenoids enhanced the liver functioning by inactivating reactive oxygen species and obstructing lipid and protein oxidative damage, the vital prophylactic strategic molecules.
In chemical differentiation,
* β-Carotene supplementation enhanced the levels of antioxidants in the tested subject that act as free radical scavengers such as vitamin C, glutathione, and glutathione-related enzymes against liver toxicity caused by administration of aflatoxin-B1.
Furthermore, β-Carotene also inhibited liver disease associated with both HBV and HCV by suppressing the elevation of inflammatory and oxidative conditions in hepatocytes.
* Lycopene found abundantly in tomato and products of tomato possesses antioxidant, and detoxification abilities in many epidemiological and animal studies, thus preventing liver oxidative stress-induced chronic diseases.
* Lutein, another phytochemical and bioactive compound found in carotenoids has been found epidemiologically to possess a strong antioxidant activity by promoting the production liver antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione, against diseases associated with oxidative stress including antiviral activity against hepatitis B.
* Other carotenoids such as β-Cryptoxanthin, α-carotene, fucoxanthin, and zeaxanthin also show promising effects against chronic liver injury through their antioxidant activity.
Taken altogether, betacyanins used alone or combined with conventional medicine may be considered a remedy for the prevention and treatment of adjuvant rheumatic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination,
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Role of Dietary Carotenoids in Different Etiologies of Chronic Liver Diseases By Uzma Latief and Riaz Ahmad
Herbal Anise extract and Essential Oil in Reduced Risk and Treatment of Nonalcoholic Fatty Liver Disease
Anise may have a potential and substantial effect in reduced risk and treatment of nonalcoholic fatty liver disease, some scientists suggested.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....
Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
Nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to statistics, nonalcoholic fatty liver disease is one of the most common causes of liver disease with a prevalence rate of 20%–30% in the Western world.
In the comparison the effect of anise fruit essential oil and extract and risk of nonalcoholic fatty liver disease, researchers at the Islamic Azad University conducted a experiment of 60 rats randomly divided into ten groups, six in each group with NAFLD induced by using choline-deficient diet for 90 days and followed by 30 days of treatment with 25, 50, 100, and 200 mg/kg/day of hydroethanolic extract (AE) as well as 0.125, 0.25, and 0.5 mg/kg/day of essential oil (AO) and found that both applications exerted a significantly reverse activities in increased AE and AO plasma levels of total cholesterol, low-density lipoprotein, and triacylglycerol and decrease in high-density lipoprotein level caused by choline-deficient diet in dose-dependent manner.
Additional differentiation also found that AE and AO reduced the elevated levels of enzymes aspartate transaminase (AST) and alanine transaminase (ALT) which are considered as an indication of either liver injury or damage caused by the acute inflammation in the experiential subject model.
Observation of injection anise AE and AO also exerted a powerful antioxidant activity in significant lower overexpression of ROS in an exhibited free radical chain reaction in the induction of oxidative stress to precipitated liver toxicity.
According to the histological findings, researchers concluded that both AE and AO display a substantial effect in reduced macrovesicular steatohepatitis which is the leading cause of liver cancer.
Further analysis also addressed that both anise AE and AO demonstrated a strong effect in ameliorated lipid peroxidation induced by oxidative stress indicated by elevation of plasma level of 8-isoprostane which is correlated to the prevalence of non-alcoholic fatty liver disease (NAFLD).
Elevated 8-Isoprostane values activated by lipid peroxidation induced by injection of choline-deficient diet are also considered as a biomarker in patients with non-alcoholic liver disease and correlated to with body mass index and with total cholesterol in NAFLD but did not significantly related to sex, age, biochemical data or iron metabolism markers in all liver diseases.
Therefore, people with high body mass index and high levels of total cholesterol levels are susceptible to increase risk of the diseases.
Taken together, herbal Anise with abundant bioactive chemical constituents and essential oil may be effective for reduced risk and treatment of nonalcoholic liver disease, but intake of herbal extract should only be prescribed by related field specialists in prevention of toxicity.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease by Asadollahpoor A1, Abdollahi M2, Rahimi R3,(PubMed)
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....
Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
Nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to statistics, nonalcoholic fatty liver disease is one of the most common causes of liver disease with a prevalence rate of 20%–30% in the Western world.
In the comparison the effect of anise fruit essential oil and extract and risk of nonalcoholic fatty liver disease, researchers at the Islamic Azad University conducted a experiment of 60 rats randomly divided into ten groups, six in each group with NAFLD induced by using choline-deficient diet for 90 days and followed by 30 days of treatment with 25, 50, 100, and 200 mg/kg/day of hydroethanolic extract (AE) as well as 0.125, 0.25, and 0.5 mg/kg/day of essential oil (AO) and found that both applications exerted a significantly reverse activities in increased AE and AO plasma levels of total cholesterol, low-density lipoprotein, and triacylglycerol and decrease in high-density lipoprotein level caused by choline-deficient diet in dose-dependent manner.
Additional differentiation also found that AE and AO reduced the elevated levels of enzymes aspartate transaminase (AST) and alanine transaminase (ALT) which are considered as an indication of either liver injury or damage caused by the acute inflammation in the experiential subject model.
Observation of injection anise AE and AO also exerted a powerful antioxidant activity in significant lower overexpression of ROS in an exhibited free radical chain reaction in the induction of oxidative stress to precipitated liver toxicity.
According to the histological findings, researchers concluded that both AE and AO display a substantial effect in reduced macrovesicular steatohepatitis which is the leading cause of liver cancer.
Further analysis also addressed that both anise AE and AO demonstrated a strong effect in ameliorated lipid peroxidation induced by oxidative stress indicated by elevation of plasma level of 8-isoprostane which is correlated to the prevalence of non-alcoholic fatty liver disease (NAFLD).
Elevated 8-Isoprostane values activated by lipid peroxidation induced by injection of choline-deficient diet are also considered as a biomarker in patients with non-alcoholic liver disease and correlated to with body mass index and with total cholesterol in NAFLD but did not significantly related to sex, age, biochemical data or iron metabolism markers in all liver diseases.
Therefore, people with high body mass index and high levels of total cholesterol levels are susceptible to increase risk of the diseases.
Taken together, herbal Anise with abundant bioactive chemical constituents and essential oil may be effective for reduced risk and treatment of nonalcoholic liver disease, but intake of herbal extract should only be prescribed by related field specialists in prevention of toxicity.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease by Asadollahpoor A1, Abdollahi M2, Rahimi R3,(PubMed)
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