Scientists may have found a natural and potent herbal plant used for the delay of skin aging, according to the studies.
Skin aging is a natural and biological process of the human which can be stopped.
Long-term free radical damage to the skin through oxidative stress is the major cause of skin aging.
Exposure to the sun (photoaging) and pollution, and loss of subcutaneous support (fatty tissue between your skin and muscle) are some of the risk factors associated with skin aging.
Some researchers suggested that skin expression may be considered as a refect of the general health of an individual. An unhealthy skin due to skin nutritional deficiency has been a target by the dermatology and cosmetic industries.
Dr.Silke K. Schagen in the study that links between nutrition and skin aging, said, "Vitamins, carotenoids, tocopherols, flavonoids and a variety of plant extracts have been reported to possess potent antioxidant properties and have been widely used in the skincare industry either as topically applied agents or oral supplements in an attempt to prolong youthful skin appearance".
The results strongly suggested that by providing enough nutrition to the skin needs, extrinsic causes of skin aging can be delayed
In skin wrinkle, according to the results of the studies by the Monash University, Melbourne, a high intake of certain food groups are associated with the speeding up of wrinkle, including meat, dairy, and butter. High intake of vegetables, legumes and olive oil appeared to be protective against cutaneous actinic damage.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits.
The herbal plant has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
With an aim to find a natural ingredient or whole food for the delay of skin aging researchers at the Seoul National University Boramae Hospital examined the effect of aloe gel on the clinical signs and biochemical changes of aging skin.
The experiment included 30 healthy female subjects over the age of 45 given 2 different doses (low-dose: 1,200 mg/d, high-dose: 3,600 mg/d) of aloe vera gel supplementation for 90 days with their baseline status as a control.
Aloe gel intake, the facial wrinkles improved significantly (p<0.05) in both groups, and facial elasticity improved in the lower-dose group.
The injection of the gel also increased the skin photoprotection and the type I procollagen mRNA levels in controlling the rate of procollagen synthesis.
The results were accompanied by the matrix (MMP-1) mRNA levels associated with breaking down the interstitial collagens, types I, II, and III, particularly in the higher-dose group.
Type I procollagen was substantially increased throughout the dermis in Aloe treatment of the group.
Dr. Cho S, the lead scientist said, "Aloe gel significantly improves wrinkles and elasticity in photoaged human skin, with an increase in collagen production in the photoprotected skin and a decrease in the collagen-degrading MMP-1 gene expression".
The Kyung Hee University Global Campus in the investigation of the effects of Aloe vera on ultraviolet (UV) irradiation induces photo-damage of the skin, which in turn causes depletion of the dermal extracellular matrix and chronic alterations in skin structure.
By the comparison of the baby Aloe shoot extract (BAE, immature aloe extract), which is from the one-month-old shoots of Aloe vera, and adult aloe shoot extract (AE), which is from the four-month-old shoots of Aloe vera, protective effect on UVB-induced skin photoaging in normal human dermal fibroblasts (NHDFs). researchers found that NHDF cells treated UVB-irradiation suppressed the matrixes associated with breaking down the interstitial collagens, types I, II, and III, and the levels of inflammatory cytokines similar to that of the above study, compared to the AE-treated cells.
BAE treatment elevated type I procollagen which was reduced in photodamaged skin. mediated by the increasing levels of TGF-β1 levels which is a multifunctional cytokine.
The findings clearly suggested that herbal Aloe vera may be considered an anti-aging functional remedy with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary Aloe Vera Supplementation Improves Facial Wrinkles and Elasticity and It Increases the Type I Procollagen Gene Expression in Human Skin in vivo. by Cho S, Lee S, Lee MJ, Lee DH, Won CH, Kim SM, Chung JH. (PubMed)
(2) A Comparative Study of Baby Immature and Adult Shoots of Aloe Veraon UVB-Induced Skin Photoaging in vitro. by Hwang E, Kim SH, Lee S, Lee CH, Do SG, Kim J, Kim SY. (PubMed)
(3) Innovations in natural ingredients and their use in skin care.
(4) Discovering the link between nutrition and skin aging by Silke K. Schagen, † Vasiliki A. Zampeli, † Evgenia Makrantonaki, and Christos C. Zouboulis. (PMC)
(5) Skin wrinkling: can food make a difference? by Purba MB1, Kouris-Blazos A, Wattanapenpaiboon N, Lukito W, Rothenberg EM, Steen BC, Wahlqvist ML. (PubMed)
(6) Prevalence of Helicobacter pylori Infection in Patients with Peptic Ulcer Diseases and Non-Ulcer Dyspepsia by Hyo Rang Lee, M.D., Ki Soo Han, M.D., Byung Chul Yoo, M.D., and Sill Moo Park, M.D. (PMC)
Please note that all articles written by Kyle. J. Norton are for information and education only, please consult with your doctor or related field specialist before applying. http://diseases-researches.blogspot.ca/
Pages
- Home
- Phytochemicals Therapy
- Regular Walking of 50+ to the World of Diseases Free and Longevity(Research and Studies)
- Recipes
- Diseases
- Men Health
- Herbal Medicine Therapy
- Super Foods
- Healthy Foods Therapy
- The Smoothie Recipes for Prevention and Treatment of Diseases and Cancers of Age of 50 Plus
- The Series of Overcome Infertility Articles
- Over 1600+ Health Articles Quoted From Experts' Medical Literature
- Children Health
- Researched and Studied Articles
- Green Tea
- 50 Plus Health; Most Common Diseases
- Dietary Minerals and Hormones
- Chinese Herbal Medicine Therapy
- Clinical trials and Studies for 50 plus Health
- Obesity's complications, Research and Studies, Articles and Weight Loss Recipes
Natural Medicine for Fatty Liver And Obesity Reversal
Wednesday, November 20, 2019
Arnica, A Potent Function Herb in Reduced Risk, Progression and Treatment of Inflammatory Arthritis
Arnica may have substantial and therapeutic values in reduced risk, progression and treatment of inflammatory arthritis, some scientists suggested.
The results of this efficacy were reported by numbers of respectable institutes and published on online medical literature, including the University of Medicine and Pharmacy and the University of Mauritius.
Arthritis is a chronic condition characterized by inflammation of more than one joint.
According to the statistic, rheumatoid arthritis, one of a common type of arthritis, is a chronic disease affecting over 1.3 million Americans and at least 1% of the worldwide population.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the finding of a natural source of alternative agent in replaced the conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects, researchers at the joint study conducted by the University of Medicine and Pharmacy, found that Arnica montana is found effective in at least in studies done in vitro or on animal models.
Other researchers also in the searching of the same by looking into the major scientific databases; Google Scholar, Pubmed, ScienceDirect, and Scopus were explored to highlight novel therapeutic approaches using herbal products for CAIDs prophylaxis, management, treatment, and prevention of relapse found that herbal products, including Arnica, can act on multiple targets involved in the pathogenesis.
In compared to other herbal and antioxidants used in the experiment, Arnica demonstrated significant activity in improved pain and physical function in patients suffering from osteoarthritis
Further analysis suggested that Arnica alleviated pain in patients with osteoarthritis was associated to reduce over immune over-response in the production of pro-inflammatory factors to the site of infection in facilitated damage and cell of the joint through its anti-inflammatory effects.
Some researchers postulated that Arnica may also reduce joint inflammation through the expression of the plant antioxidants and stimulation of the antioxidants in the host tissue, thus decreasing the risk of imbalance of the ratio of reactive oxygen species and antioxidant in precipitation of the symptoms and progression of osteoarthritis.
Dr. Mahomoodally F, the lead author after taking into account of other co and confounders, said, " In silico approaches remain also a pertinent avenue to unveil highly compatible herbal metabolites binding multiple targets involved in inflammation".
More importantly, in the animal models to investigate the therapeutic effects and mechanism of action of A. Montana flower methanol extract (AMME) against both inflammation and oxidative stress in a collagen-induced arthritis (CIA), scientists showed that application of montana flower methanol extract (AMME) exerted significant activities against both inflammation and oxidative stress in collagen-induced arthritis (CIA).
Additional differentiation found that oral administration of AMME was found to reduce clinical signs and improve the histological and radiological status of the hind limb joints by ameliorated the expression levels of nitric oxide, tumor necrosis factor-α, interleukins (IL-1β, IL-6, and IL-12) and titer of anti-type II collagen antibody compared with untreated CIA rats.
Nitric oxide (NO) is an enzyme involved in the induction of inducible type-2 isoform of nitric oxide synthase (NOS-2), in the activated toxic defense molecule against infectious organisms, however, overproduction of NO may cause cells damage and apoptosis at the site of infection.
Tumor necrosis factor-α, interleukins (IL-1β, IL-6, and IL-12) are all proinflammatroy cytokines produced by the immune system to protect cells in the infection against the invasion of microorganisms. Overexpression was also associated with the risk of cell damage and apoptosis.
High levels of type II collagen antibody is one of the biomarkers associated with concurrent but not later signs of inflammation.
Dr. Sharma S, at the end of the experiment, said, " by inhibiting these mediators, AMME also contributed towards the reversal of disturbed antioxidant levels and peroxidative damage".
Taken together, Arnica and its bio extracts may be considered as a functional food in reduced risk, progression, and treatment of inflammatory arthritis without inducing intolerant adverse effects
For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Natural Medicine for Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Cumulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress by Sharma S1, Arif M1, Nirala RK1, Gupta R2, Thakur SC1.(PubMed)
(2) Phytomedicine in Joint Disorders by Dragos D1,2, Gilca M3, Gaman L4, Vlad A5, Iosif L6, Stoian I7,8, Lupescu O(PubMed)
(3) Herbal products for common auto-inflammatory disorders - Novel approaches by Mahomoodally F1, Suroowan S1(PubMed)
The results of this efficacy were reported by numbers of respectable institutes and published on online medical literature, including the University of Medicine and Pharmacy and the University of Mauritius.
Arthritis is a chronic condition characterized by inflammation of more than one joint.
According to the statistic, rheumatoid arthritis, one of a common type of arthritis, is a chronic disease affecting over 1.3 million Americans and at least 1% of the worldwide population.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the finding of a natural source of alternative agent in replaced the conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects, researchers at the joint study conducted by the University of Medicine and Pharmacy, found that Arnica montana is found effective in at least in studies done in vitro or on animal models.
Other researchers also in the searching of the same by looking into the major scientific databases; Google Scholar, Pubmed, ScienceDirect, and Scopus were explored to highlight novel therapeutic approaches using herbal products for CAIDs prophylaxis, management, treatment, and prevention of relapse found that herbal products, including Arnica, can act on multiple targets involved in the pathogenesis.
In compared to other herbal and antioxidants used in the experiment, Arnica demonstrated significant activity in improved pain and physical function in patients suffering from osteoarthritis
Further analysis suggested that Arnica alleviated pain in patients with osteoarthritis was associated to reduce over immune over-response in the production of pro-inflammatory factors to the site of infection in facilitated damage and cell of the joint through its anti-inflammatory effects.
Some researchers postulated that Arnica may also reduce joint inflammation through the expression of the plant antioxidants and stimulation of the antioxidants in the host tissue, thus decreasing the risk of imbalance of the ratio of reactive oxygen species and antioxidant in precipitation of the symptoms and progression of osteoarthritis.
Dr. Mahomoodally F, the lead author after taking into account of other co and confounders, said, " In silico approaches remain also a pertinent avenue to unveil highly compatible herbal metabolites binding multiple targets involved in inflammation".
More importantly, in the animal models to investigate the therapeutic effects and mechanism of action of A. Montana flower methanol extract (AMME) against both inflammation and oxidative stress in a collagen-induced arthritis (CIA), scientists showed that application of montana flower methanol extract (AMME) exerted significant activities against both inflammation and oxidative stress in collagen-induced arthritis (CIA).
Additional differentiation found that oral administration of AMME was found to reduce clinical signs and improve the histological and radiological status of the hind limb joints by ameliorated the expression levels of nitric oxide, tumor necrosis factor-α, interleukins (IL-1β, IL-6, and IL-12) and titer of anti-type II collagen antibody compared with untreated CIA rats.
Nitric oxide (NO) is an enzyme involved in the induction of inducible type-2 isoform of nitric oxide synthase (NOS-2), in the activated toxic defense molecule against infectious organisms, however, overproduction of NO may cause cells damage and apoptosis at the site of infection.
Tumor necrosis factor-α, interleukins (IL-1β, IL-6, and IL-12) are all proinflammatroy cytokines produced by the immune system to protect cells in the infection against the invasion of microorganisms. Overexpression was also associated with the risk of cell damage and apoptosis.
High levels of type II collagen antibody is one of the biomarkers associated with concurrent but not later signs of inflammation.
Dr. Sharma S, at the end of the experiment, said, " by inhibiting these mediators, AMME also contributed towards the reversal of disturbed antioxidant levels and peroxidative damage".
Taken together, Arnica and its bio extracts may be considered as a functional food in reduced risk, progression, and treatment of inflammatory arthritis without inducing intolerant adverse effects
For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Natural Medicine for Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Cumulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress by Sharma S1, Arif M1, Nirala RK1, Gupta R2, Thakur SC1.(PubMed)
(2) Phytomedicine in Joint Disorders by Dragos D1,2, Gilca M3, Gaman L4, Vlad A5, Iosif L6, Stoian I7,8, Lupescu O(PubMed)
(3) Herbal products for common auto-inflammatory disorders - Novel approaches by Mahomoodally F1, Suroowan S1(PubMed)
Cranberry in the Prevention of Advanced Glycation (AD) Expression
Advanced glycation end is by produces formed by protein or fat combine with sugar caused by cooking meat at high temperatures.
The products have been found to affect metabolic health.
The most common causes of AGEs are from the diet, particularly in people who follow the Western diet with high saturated and trans fat, a lot of red meats and processed foods.
Low levels of AGEs may not be a problem, however, overexpression of AGEs can induce oxidative stress, leading to inflammation and damage proteins, lipid and sometimes alternation of cells DNA.
In other words, AGEs initiate the production and free radicals and free radical a chain reaction that can not be stopped until all electrons in the outer ring paired or inhibited by antioxidants.
Accelerated formation and accumulation of advanced glycation end-products have been found to increased hyperglycemia or oxidative stress, leading to age-related and chronic diseases such as diabetes mellitus, chronic renal failure, neurodegenerative diseases, osteoarthritis and also non-diabetic atherosclerosis and chronic heart failure.
Some researchers suggested that modern life byproducts AGEs are the results of the promotion of the processed food diet.
Dr. Chetan Sharma, Amarjeet Kaur, the lead scientist in the assessment of AGEs, wrote, "As modern diets are largely heat-processed, they are more prone to contain high levels of advanced glycation end products (AGEs)".
And, "The chemistry of the AGEs formation, absorption and bioavailability and their patho-biochemistry particularly in relation to different complications like diabetes and aging,... The emerging evidence about the adverse effects of AGEs makes it necessary to investigate the different therapies to inhibit AGEs".
The results strongly suggested the link of the modern diet with highly processed food is a leading cause of chronic diseases.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of oxidative stress, researchers examined the anti-glycation effects of several polyphenol-rich fruits, including blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts, which are rich in anthocyanins.
Berry crude extracts (CE) yielded anthocyanins-enriched (ACE) extracts used in the study, showed a significant effect against oxidative stress by exhibiting the free radical scavenging, reactive carbonyl species trapping, and anti-glycation effects compared to their respective ACFs.
Furthermore, the berry ACEs (at 100 μg/mL) inhibited both thermal- and MGO-induced Aβ fibrillation induced by the overexpression of glycation.
Moreover, the berry ACEs (at 20 μg/mL) also reduced H₂O₂-induced reactive oxygen species production and lipopolysaccharide-induced nitric oxide species in BV-2 microglia by decreasing H₂O₂-induced neuron cytotoxicity and caspase-3/7 activity in BV-2 microglia involved in inflammation.
Based on the findings, researchers said, "The free radical scavenging, reactive carbonyl trapping, anti-glycation, anti-Aβ fibrillation, and microglial neuroprotective effects of these berry extracts warrant further in vivo studies to evaluate their potential neuroprotective effects against AD".
Taken altogether, cranberry may be considered a remedy for the treatment of AD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects by Ma H1,2,3, Johnson SL4,5, Liu W6, DaSilva NA7,8, Meschwitz S9, Dain JA10, Seeram NP. (PubMed)
The products have been found to affect metabolic health.
The most common causes of AGEs are from the diet, particularly in people who follow the Western diet with high saturated and trans fat, a lot of red meats and processed foods.
Low levels of AGEs may not be a problem, however, overexpression of AGEs can induce oxidative stress, leading to inflammation and damage proteins, lipid and sometimes alternation of cells DNA.
In other words, AGEs initiate the production and free radicals and free radical a chain reaction that can not be stopped until all electrons in the outer ring paired or inhibited by antioxidants.
Accelerated formation and accumulation of advanced glycation end-products have been found to increased hyperglycemia or oxidative stress, leading to age-related and chronic diseases such as diabetes mellitus, chronic renal failure, neurodegenerative diseases, osteoarthritis and also non-diabetic atherosclerosis and chronic heart failure.
Some researchers suggested that modern life byproducts AGEs are the results of the promotion of the processed food diet.
Dr. Chetan Sharma, Amarjeet Kaur, the lead scientist in the assessment of AGEs, wrote, "As modern diets are largely heat-processed, they are more prone to contain high levels of advanced glycation end products (AGEs)".
And, "The chemistry of the AGEs formation, absorption and bioavailability and their patho-biochemistry particularly in relation to different complications like diabetes and aging,... The emerging evidence about the adverse effects of AGEs makes it necessary to investigate the different therapies to inhibit AGEs".
The results strongly suggested the link of the modern diet with highly processed food is a leading cause of chronic diseases.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of oxidative stress, researchers examined the anti-glycation effects of several polyphenol-rich fruits, including blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts, which are rich in anthocyanins.
Berry crude extracts (CE) yielded anthocyanins-enriched (ACE) extracts used in the study, showed a significant effect against oxidative stress by exhibiting the free radical scavenging, reactive carbonyl species trapping, and anti-glycation effects compared to their respective ACFs.
Furthermore, the berry ACEs (at 100 μg/mL) inhibited both thermal- and MGO-induced Aβ fibrillation induced by the overexpression of glycation.
Moreover, the berry ACEs (at 20 μg/mL) also reduced H₂O₂-induced reactive oxygen species production and lipopolysaccharide-induced nitric oxide species in BV-2 microglia by decreasing H₂O₂-induced neuron cytotoxicity and caspase-3/7 activity in BV-2 microglia involved in inflammation.
Based on the findings, researchers said, "The free radical scavenging, reactive carbonyl trapping, anti-glycation, anti-Aβ fibrillation, and microglial neuroprotective effects of these berry extracts warrant further in vivo studies to evaluate their potential neuroprotective effects against AD".
Taken altogether, cranberry may be considered a remedy for the treatment of AD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects by Ma H1,2,3, Johnson SL4,5, Liu W6, DaSilva NA7,8, Meschwitz S9, Dain JA10, Seeram NP. (PubMed)
Bromelain, the Natural Prevention and Treatment of Inflammatory Bowel Disease (IBD)
An inflammatory bowel (IBD) disease is a group of chronic inflammatory diseases associated with the digestive tract, including ulcerative colitis and Crohn's disease.
Ulcerative colitis has been found to induce chronic inflammation and ulcers in the inner lining of the large intestine (colon) and rectum.
Crohn's disease is a type of IBD associated with the inflammation of the lining of the digestive tract.
According to the statistics, provided by the CDC in the US, IBD affects over 1.3% or 3 million US adults including Crohn's disease or ulcerative colitis in 2015.
Most cases of IBD has been found in older adults in the age of 45 years or older.
Most common symptoms of IBD include diarrhea, fever, and fatigue, abdominal pain and cramping, loss of appetite and unintended weight loss.
In serious cases, some patients may also experience blood in the stool.
If you are experiencing the aforementioned symptoms, please check with your doctor to rule out the possibility.
Conventionally, most cases of IBD are treated with anti-inflammatory medicine, immune suppressor or antibiotics, and drugs that reduce symptoms, depending on the severity of the conditions.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of colitis, researchers examined the bromelain, a mixture of proteinases derived from pineapple stem in an animal model with inflammatory bowel disease (IBD).
The experiment included IL-10-/- mice treated orally with bromelain in vivo for 5 weeks.
During the study, daily treatment with oral bromelain beginning at age 5 weeks exerted a significant effect in decreased the incidence and severity of spontaneous colitis.
In IL-10-/- mice established colitis by administered to piroxicam, the proteolytic enzyme also significantly decreased the clinical and histologic severity of colonic inflammation.
In the examination of the bromelain adverse effect, researchers found that dermatitis, hair loss, and weight loss due to mucositis were rare in a dose-related manner.
In the wild-type mice, there was no adverse effect found in the dose of 1000 mg bromelain/kg/day for 18 weeks orally.
The findings clearly suggested the efficacy of bromelain for the treatment of inflammatory bowel disease (IBD).
Dr. Hale LP, the lead scientist after taking into account co confounders said, " Although the exact mechanisms by which exogenous proteinases affect bowel inflammation have not yet been determined, the results justify additional studies of this complementary biologically based approach to the treatment of IBD".
Taken altogether, bromelain may be considered supplements for the prevention and treatment of bowel disease (IBD), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease by Hale LP1, Greer PK, Trinh CT, Gottfried MR. (PubMed)
Ulcerative colitis has been found to induce chronic inflammation and ulcers in the inner lining of the large intestine (colon) and rectum.
Crohn's disease is a type of IBD associated with the inflammation of the lining of the digestive tract.
According to the statistics, provided by the CDC in the US, IBD affects over 1.3% or 3 million US adults including Crohn's disease or ulcerative colitis in 2015.
Most cases of IBD has been found in older adults in the age of 45 years or older.
Most common symptoms of IBD include diarrhea, fever, and fatigue, abdominal pain and cramping, loss of appetite and unintended weight loss.
In serious cases, some patients may also experience blood in the stool.
If you are experiencing the aforementioned symptoms, please check with your doctor to rule out the possibility.
Conventionally, most cases of IBD are treated with anti-inflammatory medicine, immune suppressor or antibiotics, and drugs that reduce symptoms, depending on the severity of the conditions.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of colitis, researchers examined the bromelain, a mixture of proteinases derived from pineapple stem in an animal model with inflammatory bowel disease (IBD).
The experiment included IL-10-/- mice treated orally with bromelain in vivo for 5 weeks.
During the study, daily treatment with oral bromelain beginning at age 5 weeks exerted a significant effect in decreased the incidence and severity of spontaneous colitis.
In IL-10-/- mice established colitis by administered to piroxicam, the proteolytic enzyme also significantly decreased the clinical and histologic severity of colonic inflammation.
In the examination of the bromelain adverse effect, researchers found that dermatitis, hair loss, and weight loss due to mucositis were rare in a dose-related manner.
In the wild-type mice, there was no adverse effect found in the dose of 1000 mg bromelain/kg/day for 18 weeks orally.
The findings clearly suggested the efficacy of bromelain for the treatment of inflammatory bowel disease (IBD).
Dr. Hale LP, the lead scientist after taking into account co confounders said, " Although the exact mechanisms by which exogenous proteinases affect bowel inflammation have not yet been determined, the results justify additional studies of this complementary biologically based approach to the treatment of IBD".
Taken altogether, bromelain may be considered supplements for the prevention and treatment of bowel disease (IBD), pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease by Hale LP1, Greer PK, Trinh CT, Gottfried MR. (PubMed)
Tuesday, November 19, 2019
Healthy Food Turmeric Protect Our Skin Against Chronic Ultraviolet B Irradiation
Ultraviolet, found in 10% of sunlight is a spectrum of wavelength between the visible light and X-rays.
Chronic ultraviolet B irradiation is a condition of long-term exposure to ultraviolet B associated with mast cell degranulation and the release of tumor necrosis factor-alpha in facilitating the production of skin proinflammatory cytokines.
Chronic ultraviolet B irradiation also links to a weakened immune system and induces the protein, lipid, and cell damage caused by the exposure to ultraviolet B in the initiation of overexpression of free radicals.
The common symptoms of chronic ultraviolet B irradiation are sunburn, darkening, and thickening of the outer layer of the skin, and in some cases, it can lead to melanoma and other types of skin cancer.
Acutely, arc-eye and snow-blindness, retinal damage and sunburn and chronically, besides skin cancer, photoaging, and senile cataracts have been found in people who expose to ultraviolet radiation in the workplace.
You can prevent chronic ultraviolet B irradiation-induced skin damage in the sunny summer days by applying sunscreen, covering your skin with proper clothing and hat, wearing sunglass, limiting yourself to go out between 11Am to 3 PM and not stay in open area to the sun for a long period of time.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of chronic ultraviolet B irradiation-induced skin damage, researchers examined the effects of turmeric on chronic ultraviolet B (UVB)-irradiated skin damage.
In low-dose ultraviolet B irradiation in melanin-possessing hairless mice, extract (at 300 or 1000 mg/kg, twice daily) exerted a significant skin protective activity by preventing an increase in skin thickness and a reduction in skin elasticity.
Furthermore, the extract also prevented the formation of wrinkles and melanin (at 1000 mg/kg, twice daily) and protected the skin by increasing the diameter and length of skin blood vessels.
Moreover, turmeric extract also exhibited the expression of important enzymes (matrix metalloproteinase-2 (MMP-2)) involved in skin tissue metabolism.
Based on the finding, researchers said, "Prevention of UVB-induced skin aging by turmeric may be due to the inhibition of increases in MMP-2 expression caused by chronic irradiation".
In order to reveal more information about turmeric skin protective effect, researchers examined the ability of curcumin (Cur) on human dermal fibroblasts (HDFs) against ultraviolet A (UVA)-induced photoaging.
The study included HDFs treated with 0–10 µM Cur for 2 h and subsequently exposed to various intensities of UVA irradiation.
According to the tested assays, Cur reduced the accumulation of ROS and restored the activity of antioxidant defense enzymes induced by UVB exposure.
Additionally, the pretreatment of Cur. only inhibited the endoplasmic reticulum (ER) stress, inflammation, and skin cell apoptosis associated with UVB but also regulated regulate collagen metabolism by decreasing the protein expression of matrix metalloproteinase (MMP)-1 and MMP-3 in collagen degradation.
Researchers after taking other factors into account wrote, "potential benefits of Cur for the protection of HDFs against UVA-induced photoaging and highlight the potential for the application of Cur in skin photoprotection".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of chronic ultraviolet B irradiation-induced skin damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice by Sumiyoshi M1, Kimura Y. (PubMed)
(2) Protective effect of curcumin against ultraviolet A irradiation-induced photoaging in human dermal fibroblasts by Xiaoming Liu,1 Ruizhi Zhang,1 Haixia Shi,1 Xiaobo Li,2,5 Yanhong Li,3 Ahmad Taha,4 and Chunxing Xu. (PMC)
Chronic ultraviolet B irradiation is a condition of long-term exposure to ultraviolet B associated with mast cell degranulation and the release of tumor necrosis factor-alpha in facilitating the production of skin proinflammatory cytokines.
Chronic ultraviolet B irradiation also links to a weakened immune system and induces the protein, lipid, and cell damage caused by the exposure to ultraviolet B in the initiation of overexpression of free radicals.
The common symptoms of chronic ultraviolet B irradiation are sunburn, darkening, and thickening of the outer layer of the skin, and in some cases, it can lead to melanoma and other types of skin cancer.
Acutely, arc-eye and snow-blindness, retinal damage and sunburn and chronically, besides skin cancer, photoaging, and senile cataracts have been found in people who expose to ultraviolet radiation in the workplace.
You can prevent chronic ultraviolet B irradiation-induced skin damage in the sunny summer days by applying sunscreen, covering your skin with proper clothing and hat, wearing sunglass, limiting yourself to go out between 11Am to 3 PM and not stay in open area to the sun for a long period of time.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a potential compound for the treatment of chronic ultraviolet B irradiation-induced skin damage, researchers examined the effects of turmeric on chronic ultraviolet B (UVB)-irradiated skin damage.
In low-dose ultraviolet B irradiation in melanin-possessing hairless mice, extract (at 300 or 1000 mg/kg, twice daily) exerted a significant skin protective activity by preventing an increase in skin thickness and a reduction in skin elasticity.
Furthermore, the extract also prevented the formation of wrinkles and melanin (at 1000 mg/kg, twice daily) and protected the skin by increasing the diameter and length of skin blood vessels.
Moreover, turmeric extract also exhibited the expression of important enzymes (matrix metalloproteinase-2 (MMP-2)) involved in skin tissue metabolism.
Based on the finding, researchers said, "Prevention of UVB-induced skin aging by turmeric may be due to the inhibition of increases in MMP-2 expression caused by chronic irradiation".
In order to reveal more information about turmeric skin protective effect, researchers examined the ability of curcumin (Cur) on human dermal fibroblasts (HDFs) against ultraviolet A (UVA)-induced photoaging.
The study included HDFs treated with 0–10 µM Cur for 2 h and subsequently exposed to various intensities of UVA irradiation.
According to the tested assays, Cur reduced the accumulation of ROS and restored the activity of antioxidant defense enzymes induced by UVB exposure.
Additionally, the pretreatment of Cur. only inhibited the endoplasmic reticulum (ER) stress, inflammation, and skin cell apoptosis associated with UVB but also regulated regulate collagen metabolism by decreasing the protein expression of matrix metalloproteinase (MMP)-1 and MMP-3 in collagen degradation.
Researchers after taking other factors into account wrote, "potential benefits of Cur for the protection of HDFs against UVA-induced photoaging and highlight the potential for the application of Cur in skin photoprotection".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of chronic ultraviolet B irradiation-induced skin damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice by Sumiyoshi M1, Kimura Y. (PubMed)
(2) Protective effect of curcumin against ultraviolet A irradiation-induced photoaging in human dermal fibroblasts by Xiaoming Liu,1 Ruizhi Zhang,1 Haixia Shi,1 Xiaobo Li,2,5 Yanhong Li,3 Ahmad Taha,4 and Chunxing Xu. (PMC)
Herbal Ashwagandha Effects on Chronic Stress Induced Anxiety
Chronic stress is the response to emotional pressure in demanding situations over a period of time, leading to the release of hormone cortisol and adrenaline.
Most common factors associated with stress incidence include psychological pressures, such as work deadlines, and exams, high-pressure jobs, and financial difficulties.
Overtime unresolved chronic stress can cause a wide range of symptoms and increase the risk of developing certain illnesses, including anxiety.
Anxiety disorder is a class of medical conditions associated with chronic worries and fear, leading to symptoms of the fast heart rate and shakiness.
Most people with anxiety may experience the feeling of nervousness in responding to events such as a problem at work, before taking a test, or before making an important decision.
According to the statistics, anxiety disorders are the most common mental illness in Canada and approximately 1 in every 8 Canadians is affected by the illness. In other words, over 250,000 people in Canada suffer from anxiety.
Most common prevalent factors that induce the risk of the condition are, family history, gender (women are more likely diagnosed with the condition compared to men), chronic stress, people with traumatic life experiences and the use of substances are some prevalent risk factors of anxiety.
However, some researchers suggested a moderate physical activity, mind-body practices of breathing exercises, yoga, and meditation has been found to reduce stress, a strong positive impact against anxiety.
The Anxiety and Depression Association of America wrote, "Whether, in good times or bad, most people say that stress interferes at least moderately with their lives. Chronic stress can affect your health, causing symptoms from headaches, high blood pressure, and chest pain to heart palpitations, skin rashes, and loss of sleep".
"Physical activity is a proven way to reduce stress. Regular participation in aerobic exercise has been shown to decrease overall levels of tension, elevate and stabilize mood, and improve sleep and self-esteem. Other effective methods include mind-body practices of breathing exercises, yoga, and meditation".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belongings to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of anxiety, researchers examined the safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha roots in reducing stress and anxiety.
The single-center, prospective, double-blind, randomized, placebo-controlled trial included a total of 64 patients with a history of chronic stress received either each capsule contained 300 mg of high-concentration full-spectrum extract from the root of the Ashwagandha plant on Day 15, Day 30 and Day 45 or placebo, was conducted by the Department of Neuropsychiatry and Geriatric Psychiatry, Asha Hospital,
According to the performing relevant clinical examinations and laboratory tests, compared to the baseline, the extracts treatment group showed a exhibited a significant reduction in scores on all the stress-assessment scales on Day 60.
Compared to the placebo group, anxiety associated with the serum cortisol levels were decreased substantially in the Ashwagandha group.
There are only mild and tolerate adverse effect comparable in both the groups. In other words, Ashwagandha showed no serious side effects during the experiment.
Collectively, herbal Ashwagandha and its extract enhanced the hormone expression associated with stress in the initiation of anxiety.
Dr. Chandrasekhar K, the lead scientist said, " a high-concentration full-spectrum Ashwagandha root extract safely and effectively improves an individual's resistance towards stress and thereby improves self-assessed quality of life".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of chronic stress and anxiety with no side effects, pending to the results of the larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial by Choudhary D1, Bhattacharyya S2, Joshi K. (PubMed)
(2) A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults by Chandrasekhar K1, Kapoor J, Anishetty S. (PubMed)
(3) Understand the Facts, Stress by The Anxiety and Depression Association of America
Most common factors associated with stress incidence include psychological pressures, such as work deadlines, and exams, high-pressure jobs, and financial difficulties.
Overtime unresolved chronic stress can cause a wide range of symptoms and increase the risk of developing certain illnesses, including anxiety.
Anxiety disorder is a class of medical conditions associated with chronic worries and fear, leading to symptoms of the fast heart rate and shakiness.
Most people with anxiety may experience the feeling of nervousness in responding to events such as a problem at work, before taking a test, or before making an important decision.
According to the statistics, anxiety disorders are the most common mental illness in Canada and approximately 1 in every 8 Canadians is affected by the illness. In other words, over 250,000 people in Canada suffer from anxiety.
Most common prevalent factors that induce the risk of the condition are, family history, gender (women are more likely diagnosed with the condition compared to men), chronic stress, people with traumatic life experiences and the use of substances are some prevalent risk factors of anxiety.
However, some researchers suggested a moderate physical activity, mind-body practices of breathing exercises, yoga, and meditation has been found to reduce stress, a strong positive impact against anxiety.
The Anxiety and Depression Association of America wrote, "Whether, in good times or bad, most people say that stress interferes at least moderately with their lives. Chronic stress can affect your health, causing symptoms from headaches, high blood pressure, and chest pain to heart palpitations, skin rashes, and loss of sleep".
"Physical activity is a proven way to reduce stress. Regular participation in aerobic exercise has been shown to decrease overall levels of tension, elevate and stabilize mood, and improve sleep and self-esteem. Other effective methods include mind-body practices of breathing exercises, yoga, and meditation".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belongings to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of anxiety, researchers examined the safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha roots in reducing stress and anxiety.
The single-center, prospective, double-blind, randomized, placebo-controlled trial included a total of 64 patients with a history of chronic stress received either each capsule contained 300 mg of high-concentration full-spectrum extract from the root of the Ashwagandha plant on Day 15, Day 30 and Day 45 or placebo, was conducted by the Department of Neuropsychiatry and Geriatric Psychiatry, Asha Hospital,
According to the performing relevant clinical examinations and laboratory tests, compared to the baseline, the extracts treatment group showed a exhibited a significant reduction in scores on all the stress-assessment scales on Day 60.
Compared to the placebo group, anxiety associated with the serum cortisol levels were decreased substantially in the Ashwagandha group.
There are only mild and tolerate adverse effect comparable in both the groups. In other words, Ashwagandha showed no serious side effects during the experiment.
Collectively, herbal Ashwagandha and its extract enhanced the hormone expression associated with stress in the initiation of anxiety.
Dr. Chandrasekhar K, the lead scientist said, " a high-concentration full-spectrum Ashwagandha root extract safely and effectively improves an individual's resistance towards stress and thereby improves self-assessed quality of life".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and treatment of chronic stress and anxiety with no side effects, pending to the results of the larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial by Choudhary D1, Bhattacharyya S2, Joshi K. (PubMed)
(2) A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults by Chandrasekhar K1, Kapoor J, Anishetty S. (PubMed)
(3) Understand the Facts, Stress by The Anxiety and Depression Association of America
Herbal Aloe Vera, the Potential Anti Prostate Cancer Functional Remedy
Herbal Aloe vera may be used for the prevention and treatment of prostate cancer with no side effects, some scientists suggested.
Prostate cancer is a slow-growing cancer characterized by irregular cell growth in the prostate tissue.
Most cases of prostate cancer start in the cells on the surface of the inner lining tissue. However, at
the advanced stage, cancerous prostate cells can travel a distance away to infect other healthy tissue and organs, causing the secondary metastasis. Most often, prostate cancer spreads to the bones or lymph nodes.
Most prostate cancers may be detected during the physical (rectum) exams.
According to the statistic, 1 man in 9 will be diagnosed with prostate cancer during his lifetime. 6 cases in 10 are diagnosed in men aged 65 or older and the average age at the time of diagnosis is about 66.
The 5-year survival rate for most men with stage 0 and 1 prostate cancer is nearly 100%. Ninety-eight percent (98%) are alive after 10 years.
These results strongly indicated that men who are at a higher risk of prostate cancer due to family history and genetic proposition should have a prostate exam taken every year.
Besides aging, other most common risk factors of prostate cancer include family history, ethnicity, genetic preposition, exposure to agent orange and eating habits.
Dr. Wambui G. Gathirua-Mwangi, the lead author in the cancer team in the joint study led by the Indiana University, wrote, "Epidemiologic studies have overall showed that the habitual consumption of a diet high in saturated fat, well-done meats, and calcium is associated with an increased risk of advanced prostate cancer".
And, "measure the nutrients and their biochemical indicators, the risk of advanced prostate cancer, which is fatal and thus clinically significant, may be reduced by dietary modification or chemoprevention".
The finding strongly indicated a healthy diet high in fruits and vegetables and whole-grain and low in
saturated and trans fat, red meat and processed foods have a decreased risk of prostate cancer.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits.
The herbal plant has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include Aloe-Emodin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharides, polysaccharides, salicylic acid, saponins, and sterols.
On finding a natural compound or ingredient for the treatment of prostate cancer with no side effects, researchers at the Korea Research Institute of Bioscience and Biotechnology evaluated phytochemical Aloe-emodin, a bioactive compound isolated from the Aloe vera against prostate cancer on the protein
Aloe-emodin inhibited both proliferation and anchorage-independent growth of PC3 cells.
The efficacy of the inhibited was found to involve proteins that exhibit androgen-refractory prostate cell proliferation and anchorage-independent growth through cancer cell metabolism.
Furthermore, Aloe-emodin demonstrated a significant effect against the activation of a protein (mTORC2) in stimulating the cancer cell proliferation and migration.
Interestingly, researchers also found that Aloe-emodin also inhibits the gene associated with tumor promoter, namely Protein kinase C alpha (PKCα).
Expression of protein kinase C alpha (PKCα) has a strong implication in cancer metastasis and poor prognosis.
In other words, Aloe-emodin displays significant anti-prostate cancer properties by inhibiting cancer cell proliferation, migration through binging to proteins associated with them.
In vivo, Aloe-emodin also exhibited tumor suppression effects in an athymic nude mouse model.
Dr. Liu K after taking into account co and confounders said, "aloe-emodin suppresses prostate cancer progression by targeting mTORC2".
Taken altogether, herbal Aloe vera may be considered a functional remedy for the prevention and combined with primary medicine for the treatment of prostate cancer with no side effect, pending to the confirmation of large sample size and multicenter human study.
Intake of supplement Aloe-emodin should be taken with extreme care to prevent overdoses induced acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2 by Liu K, Park C, Li S, Lee KW, Liu H, He L, Soung NK, Ahn JS, Bode AM, Dong Z, Kim BY, Dong Z.(PubMed)
Subscribe to:
Posts (Atom)