Monday, December 2, 2019

Herbal Coltsfoot (Tussilago farfara), the Potent Antibacterial Antibiotic

The bacterial infection is the inflammation caused by the multiplication of bacterias after entering the body successfully.

The process of infection can be divided into many stages. However, most bacterias that try to invade the body were killed in the acute phase of infection by the immune system response through the production of the pro-inflammatory cytokines stimulated by the white blood cell macrophages.

According to the statistic provided by the CDC, each year in the U.S., at least 2 million people get an antibiotic-resistant infection, and at least 23,000 people die due to bacterial infectious disease.

Most people do not experience any symptoms until the microbe multiplication to the peak in its’ population.

Acute infection in most cases is recovered with a week or two. However, if the immune function cannot destroy all the bacterias within 3 to 8 weeks, it will compromise, leading to chronic low-grade inflammatory diseases.

The most common and classical symptoms of acute infection are aches, pains, fever, malaise, and nausea.

The chronic low-grade inflammatory state is a pathological feature of a wide range of chronic conditions, such as metabolic syndrome (MetS), non-alcoholic fatty liver disease (NAFLD), type 2 diabetes.

A most common risk of bacterial infection is a weakened immune system, particularly in the elderly.

The Institute of Medicine (US) Division of Health Promotion and Disease Prevention in examing the risk of infection in elderly, wrote, "The implications of an aging population for health care are being widely discussed but seldom with the understanding that health promotion and disability prevention are workable concepts for people in the “second 50” years of life".

And, "Pneumonia and influenza are among the leading causes of death and morbidity from infection among older people. Safe and effective vaccines to prevent pneumonia and influenza are available and should be universally used in persons over age 50. Nosocomial (institutionally acquired) infections have a major deleterious impact on persons over 50 and require good infection control practices in hospitals and nursing homes".

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound for the treatment of bacterial infection, researchers examined the effect of the flower bud extract of Tussilago farfara on Gram-positive and Gram-negative bacteria.

The study is to compare the antibacterial activity of silver and gold nanoparticles of sesquiterpenoids from T. farfara flower bud extract and the use of extract alone.

According to the tested analysis, the silver nanoparticles exerted a two- to four-fold enhancement of the extract compared to the extract alone in the treatment of both Gram-positive and Gram-negative bacteria.

The solver nanoparticles also showed the highest antibacterial activity against vancomycin-resistant Enterococci Van-A type Enterococcus facium, compared to the extract alone.

Based on the findings, researchers said, " both nanoparticles synthesized with the sesquiterpenoids from T. farfara flower bud extract can be applied as drug delivery vehicles of anticancer or antibacterial agents for future nanomedicine applications.s".

Taken altogether, coltsfoot and silver and gold nanoparticles of sesquiterpenoids from T. farfara flower bud extract may be considered remedies for the treatment of bacterial infection, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Chemical composition and antibacterial activity of Tussilago farfara (L.) essential oil from Quebec, Canada by Boucher MA1, Côté H1, Pichette A1, Ripoll L1, Legault J. (PubMed)
(2) Sesquiterpenoids from Tussilago farfara Flower Bud Extract for the Eco-Friendly Synthesis of Silver and Gold Nanoparticles Possessing Antibacterial and Anticancer Activities by Lee YJ1, Song K2, Cha SH3, Cho S4, Kim YS5, Park Y. (PubMed)
(3) The Second Fifty Years by Promoting Health and Preventing Disability (1992). (NCBI)

Herbal Chickweed, The Natural and Potential Remedy Which Protects Our Liver Against Hepatitis

Scientists may have found a single whole herb that processes a significant effect in reducing the risk and treatment of hepatitis with no side effects, some studies suggested.

Hepatitis is a group of the infectious disease characterized by the inflammation of the liver.

Most cases of hepatitis are caused by a viral infection, such as hepatitis A, B, and C. However, the disease also can be induced by excessive alcohol drinking and long-term intake of certain medications such as the popular Nonsteroidal anti-inflammatory drugs (NSAIDs).

Genetic preposition such as gene and certain medical conditions such as Cryoglobulinemia, a disease with an abnormality of the antibody and B-cell non-Hodgkin's lymphoma are also found to elevate the risk of the disease onset.

Dr. Zheng Zeng in the study "Human genes involved in hepatitis B virus infection", wrote, " There is an approximate 90% risk of becoming a persistent carrier following perinatal infection in infants born to e antigen-positive carrier mothers and a 30% risk in pre-school children. Only 5%-10% of adults become persistent carriers following infection".


Hepatitis is a very contagious disease. people who eat food or drink beverages contaminated with the feces of an infected person are easily infected by the virus.

Fishes and selfish that grow in the polluted water are also found to infected people with the hepatitis virus.

Other risk factors associated with liver inflammation also include liver disease, cirrhosis, and liver toxicity.

According to the investigation of hepatitis infection among 563 adult Swedish expatriates suggested, "The most frequently reported recognised risk factors for the acquisition of viral hepatitis (as reported in a self-administered questionnaire) were having received an inoculation during medical or dental treatment, reported by 45% of all subjects, and having had sexual contact with the indigenous population, reported by 35%" and "the prevalences of hepatitis A virus (HAV) and hepatitis C virus (HCV) markers in these expatriates were of the same magnitude as previously reported in the general Swedish population, 8% and 0.3%, respectively, the prevalence of markers for a past or present HBV infection was about twice as high (5%)".

Chickweed is a cool-season annual plant often eaten by chickens., genus S. media, belonging to the family Caryophyllaceae, native to Europe.

The herb has been used in herbal medicine to treat skin conditions, indigestion, eczema, cough, rashes, etc. and as astringent, carminative, demulcent, diuretic, expectorant, laxative, refrigerant, vulnerary agent.

In the study to reaffirm the use of Chickweed in traditional Chinese medicine for the treatment of viral infection, researchers at the Jiangsu Provincial Academy of Chinese Medicine conducted an evaluation to examine the anti-hepatitis virus of fresh juice made from the herbal medicine.

All the fresh chickweed juices were prepared by the macroporous resin and ultrafiltration technology.


In vitro, the human HBV-transfected liver cell line HepG2.2.15. after treatment with fresh chickweed juices for 6 or 9 days, with the injection of 30 μg/mL SM-3 effectively suppressed the secretion of HBsAg and HBeAg with inhibition rates of 27.92% and 25.35% after 6 days of treatment of HepG2.2.15 cells, respectively.

The application of SM-3 reduced the level of HBV DNA in a dose-dependent manner.

Furthermore, the SM-3 also exerted a potential effect on the reduction in HBV antigens.

Moreover, in the examine the characterization and quantitation of the chemical composition of SM-3, researchers discovered that the efficacy of SM-3 in the inhibition of the human HBV-transfected liver cell line HepG2.2.15 was results of antiviral activities of the presence of flavonoid C-glycosides, polysaccharides, and protein found in the herb.

These results strongly suggested that herbal Chickweed possesses potential anti-HBV activity in vitro.

Additionally, in the examine the anti-hepatoma activity on five human liver-cancer cell lines, i.e. HepG2/C3A, SK-HEP-1, HA22T/VGH, Hep3B and PLC/PRF/5. of 15 15 herbal medicines used as folk medicine in Canada were evaluated by the McGill University.

Chickweed was found to exert a significant effect in the protection of the liver against the growth of all five cell lines, HepG2/C3A, SK-HEP-1, HA22T/VGH, Hep3B and PLC/PRF/5.


Taken altogether, Chickweed may be considered a function of herbal medicine for the prevention and treatment of hepatitis.

However, due to the limitation of the above studies, additional data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of Chickweed anti-hepatitis possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) In vitro anti-hepatoma activity of fifteen natural medicines from Canada by Lin LT1, Liu LT, Chiang LC, Lin CC. (PubMed)(2) Bioactive constituents from Chinese natural medicines. XIV. New glycosides of beta-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities by Morikawa T1, Sun B, Matsuda H, Wu LJ, Harima S, Yoshikawa M.(PubMed
(3) Anti-hepatitis B virus activity of chickweed [Stellaria media (L.) Vill.] extracts in HepG2.2.15 cells by Ma L1, Song J, Shi Y, Wang C, Chen B, Xie D, Jia X.(PubMed)
(4) Evaluation of hepatoprotective activity of water-soluble polysaccharide fraction of Stellaria media L. by Gorina YV1, Saprykina EV, Gereng EA, Perevozchikova TV, Krasnov EA, Ivanova EV, Fait EA, Baranova OV. (PubMed)
(5) In vitro anti-hepatoma activity of fifteen natural medicines from Canada by Lin LT1, Liu LT, Chiang LC, Lin CC. (PubMed)

Sunday, December 1, 2019

Herbal Cayenne May Process A Potency to Cure Allergic Rhinitis


Herbal cayenne may be a pharmaceutical target to identify the single ingredient medicine for the treatment of allergic rhinitis with no side effects, some scientists suggested.

Nonallergic rhinitis is a condition with symptoms that resemble allergy causes of rhinitis but without a known cause.

Chronic forms of rhinitis occurred in the absence of any detectable specific IgE against relevant aeroallergens in its broadest sense can be called chronic nonallergic rhinitis.

Allergic rhinitis is caused by the immune overreaction when a person breathes in an allergen such as pollen, mold, animal dander, or dust, leading to the irritation and inflammation of the mucous membrane inside the nose.

The most common symptoms of allergic rhinitis are the stuffy nose, runny nose, sneezing, and post-nasal drip.

Contrast to general belief, allergic rhinitis is not the syndrome which comes and goes depending on the seasons.

Untreated allergic rhinitis can lead to complications of chronic nasal inflammation and obstruction, a leading cause of upper respiratory tract infection.

There is some strong evidence suggested that allergic rhinitis can affect the quality of life, productivity, and other comorbid conditions, including asthma.

The World Health Organization in the differentiation fo the condition, suggesting that the treatment of allergic rhinitis should include a combination of patient education, allergen avoidance, pharmacotherapy, and immunotherapy

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.

The kitchen spice has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.

The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.

In finding a natural formula for the treatment of allergic rhinitis with no side effects, researchers at the University of Cincinnati College of Medicine examine the efficacy and safety of ICX72 or Sinus Buster, a proprietary homeopathic preparation of Capsicum annum and Eucalyptol, versus placebo.

In the total of Forty-two consented subjects meeting inclusion/exclusion criteria randomized to ICX72 (n = 20) or control (n = 22) administered twice daily over 2 weeks, the primary endpoint was changed in total nasal symptom scores (TNSS) from baseline to end of the study.

During the study, the application of ICX72 exhibited significant differences in changes from baseline to end of study for TNSS and each ISS (P < .01), compared to placebo.

ICX72 exerted a significantly faster relief at 52.6 seconds.

The formula also improved nasal congestion, sinus pain, sinus pressure, and headache at 5, 10, 15, and 30 minutes, persisting at 60 minutes for nasal congestion and sinus pain.

No subjects experienced rebound congestion or impaired olfaction at the end of the study.

There is no adverse effect in the treatment group.

These results firmly suggested that intranasal capsaicin used continuously over 2 weeks, rapidly and safely improves symptoms in rhinitis subjects with a significant NAR component.

Further analysis of the effect of intranasal capsaicin, researchers conducted a double-blind double-dummy parallel-group trial to determine whether a more practical capsaicin application schedule is equally effective.

Thirty patients were randomized into two different treatment regimens: one group received capsaicin five times on the first day at 1-h intervals, followed by a placebo dummy once every second or third day for a total of five treatments 2 weeks after the capsaicin application (group A).

The other group (B) received the placebo dummy five times on the first day followed by capsaicin once every second or third day for a total of five treatments 2 weeks after the placebo application.

According to the reading, visual analog scale scores for overall nasal symptoms, group A showed significant deeper decrease rhinorrhea and nasal blockage, compared to group B.

There is a significant reduction in the cold dry air responsiveness up to 9 months after therapy in both groups, reflecting a decrease in nasal hyperreactivity.

Taken altogether, Herbal cayenne containing bioactive compound capsaicin may be considered a functional spice for the treatment of allergic rhinitis with no side effects.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Nonallergic rhinitis by Lieberman P1, Pattanaik D.(PubMed)
(2) A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis by Bernstein JA1, Davis BP, Picard JK, Cooper JP, Zheng S, Levin LS. (PubMed)
(3) Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study by Van Rijswijk JB1, Boeke EL, Keizer JM, Mulder PG, Blom HM, Fokkens WJ. (PubMed)

Herbal Calendula in the Prevention and Treatment of Atherosclerosis

The finding a natural ingredient for the treatment of atherosclerosis without inducing any side effect has been a lifetime dream of many scientists.

Calendula, a herbal medicine under intensive studies may have a potential effect in the prevention and treatment of atherosclerosis, according to some studies.

Atherosclerosis is a medical condition caused by long-term plaques building up on the wall of the arteries, leading to the reduced oxygen-rich blood flow to the heart.

Plaques mostly are made up of fat, cholesterol, calcium, found in the blood.

Some researchers suggested the most common risk factors according to the epidemiological studies are a poor diet high in saturated and trans fat, red meat and processed foods and fewer fruits and vegetable and unhealthy lifestyle and physical inactivity.

However, the role of calcium in the diet is one of the less being mentioned in the medical literature.

In examining the complexity of the atherosclerotic process, researchers showed that calcium also plays an important role in the formation of plaques in the arteries.

The calcium mineralization of the lumen in the atherosclerotic artery promotes and solidifies plaque formation causing narrowing of the vessel, leading to the soft tissue calcification associated with tissue generation.

The deposition of minerals in the form of calcium (Ca(2+)) initially transformed from the mineral octacalcium phosphate, a precursor of hydroxylapatite are found to contribute to calcium deposited in the wall of arteries.

Dr. John J. B. Anderson, the lead scientists in the study "Risk of High Dietary Calcium for Arterial Calcification in Older Adults" said, "high calcium intakes in free-living adults have relatively little or no beneficial impact on bone mineral density (BMD) and fracture rates suggest that current recommendations of calcium for adults may be set too high" and "The maintenance of BMD and bone health continues to be an important goal of adequate dietary calcium consumption, but eliminating potential risks of CVDs from excessive calcium intakes needs to be factored into policy recommendations for calcium by adults".

The differentiation indicated that elderly who are overtaking calcium supplements to improve bone density may be at the higher risk of the arterial calcification, a leading cause of atherosclerosis

Calendula is also known as pot marigold, annual or perennial herbaceous plants of about 12–20 species of genus Calendula, belonging to the family Asteraceae, native to Southern Europe.

The plant has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and to treat abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.

The chemical ingredients of calendula include triterpenoids, flavonoids, coumarines, quinones, volatile oil, carotenoids, loliolide (calendin), calendulin and n-paraffins.

In the finding natural products including botanicals for both therapy of clinical manifestations of atherosclerosis and reduction of atherosclerosis risk factors, researchers examined the antiatherosclerotic effect of formulas Inflaminat (calendula, elder and violet), and phytoestrogen-rich Karinat (garlic powder, extract of grape seeds, green tea leafs, hop cones, β-carotene, α-tocopherol, and ascorbic acid).

In a total of 196 asymptomatic men aged 40-74 in the double-blinded placebo-controlled randomized clinical study, researchers found that both formulas have a direct anti-atherosclerotic effect on carotid atherosclerosis and this effect is likely to be due to serum atherogenicity inhibition, according to The AMAR (Atherosclerosis Monitoring and Atherogenicity Reduction) assay.

Further investigation of the natural products, the promising drugs for anti-atherosclerotic therapy, using cellular models and natural products, researchers suggested that the formula Inflaminat (calendula, elder, and violet), which possesses anti-cytokine activity, shows to induce the regression of carotid atherosclerosis following the treatment of asymptomatic men for one year.


Dr. Orekhov AN, after taking another assessment of the 2 studies wrote, "our basic findings were successfully translated into clinical practice. Because of this translation, a novel approach to antiatherosclerotic therapy was developed".

Moreover, in the study"Use of natural products in anti-cytokine therapy in the evaluation of botany products which has been used in traditional medicine for the treatment of atherosclerosis researchers also found a formula of medicinal plants (calendula, elder, and pansy) with maximum anti-inflammatory activity.


The application of the formula was found effective in reducing the production of a proinflammatory cytokine in facilitating the formation of plaques in the arteries.

Dr. Gorchakova TV, the lead author said, at the final report, "The combination can be used for pathogenetic therapy of various inflammatory diseases, including atherosclerosis".

Taken altogether, herbal calendula may be considered a functional food for the prevention and combined with other herbal medicines for the treatment of atherosclerosis, without inducing any side effects.


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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anti-atherosclerotic therapy based on botanicals by Orekhov AN1, Sobenin IA, Korneev NV, Kirichenko TV, Myasoedova VA, Melnichenko AA, Balcells M, Edelman ER, Bobryshev YV.(PubMed)
(2) Direct anti-atherosclerotic therapy; development of natural anti-atherosclerotic drugs preventing cellular cholesterol retention by Orekhov AN(PubMed)
(3) Use of natural products in anti-cytokine therapy by Gorchakova TV1, Suprun IV, Sobenin IA, Orekhov AN(PubMed)
(4) Risk of High Dietary Calcium for Arterial Calcification in Older Adults by John J. B. Anderson1,* and Philip J. Klemmer. (PMC)

Chaste tree berry (Vitex agnus-castus) on Leukaemia

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region. It has been used in herbal medicine for thousands of years as an aphrodisiac herb and is considered as Queen herb in treating menstrual problems and discomforts by taking it in a prolonged period of time. There was a report that reports chaste tree berry stems and leaves used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria,

Chemical constituents
1. β-citronellol
2. Labdane-type diterpenoids,
3. Halimane-type diterpenoid,
4. Oleanane-type triterpenoids,
5. Ursane-type triterpenoids,
6. Sesquiterpenoid,
7. Flavonoid
8. Viteagnusins C, D, E, F, G, and H
9. Abietane-type diterpenoids


Leukemia is defined as a condition of an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
Bone marrow is soft tissue inside the hollow center of major bone. including spine, pelvis, underarm, leg. etc.
Chaste tree berry may process an anti-leukemia effect. According to the Tokyo University of Pharmacy and Life Sciences, Chaste tree berry extract inhibited HL60 liver cancer cell line through induced a dose- and time-dependent decrease in cell viability associated with induction of apoptosis and G2/M cell cycle arrest in a dose- and time-dependent manner(1). Also on leukemia cell lines, HL-60 and U-937, extract from the ripe fruit of Vitex agnus-castus (Vitex), inhibited both cell lines through its cytotoxicity activity in a dose dependent manner(2).


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References
(1) Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus fruit extract by chi H1, Yuan B1, Yuhara E1, Imai M1, Furutani R1, Fukushima S1, Hazama S1, Hirobe C2, Ohyama K1, Takagi N3, Toyoda H1.(PubMed)
(2) Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines by chi H1, Yuan B, Nishimura Y, Imai M, Furutani R, Kamoi S, Seno M, Fukushima S, Hazama S, Hirobe C, Ohyama K, Hu XM, Takagi N, Hirano T, Toyoda H.(PubMed)

Cinnamon: The Best Immunomodulatory Whole food Medicine

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

Intake of cinnamon may induce an immunomodulatory effect in regular immune function against certain diseases such as autoimmunity. According to the Kyung Hee University, water extract of cinnamon bark (CWE) exerted the effect on cytokine secretion and activation of T cells.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections.

Sodium benzoate (NaB), a metabolite of cinnamon ameliorated clinical symptoms and disease progression of allergic encephalomyelitis caused by immune overreaction induced inflammation, through enriched regulatory T cell population, and down-regulated the expression of various contact molecules in T cells.

Dr. Pahan K said, "Sodium benzoate (NaB), a metabolite of cinnamon and an FDA-approved drug against urea cycle disorders in children, ......, regulates many immune signaling pathways responsible for inflammation, glial cell activation, switching of T-helper cells, modulation of regulatory T cells, cell-to-cell contact, and migration"
Orofacial granulomatosis (OFG) is a chronic inflammatory disorder with symptoms of inflammation such as lip swelling but also affecting gingivae, buccal mucosa, the floor of the mouth,.....
cinnamon- and benzoate-free diet, after 8 weeks of treatment, significantly improve both lips and oral site.

Furthermore, the experiment of cinnamon (Cinnamomum zeylanicum) bark essential oil (CBEO) on human skin cells showed strong anti-proliferative effects on skin cells and significantly inhibited the production of several inflammatory biomarkers expressed by autoimmunity.

Cinnamon may improve immune expression and reduce risk of autoimmune diseases, intake of the whole herb should be taken with care in the prevention of toxicity



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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


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Sources
(1) Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation by Lee BJ1, Kim YJ, Cho DH, Sohn NW, Kang H.(PubMed)
(2) Immunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate by Pahan K1.(PubMed)
(3) Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis by Brahmachari S1, Pahan K.(PubMed)
(4) Improvement in orofacial granulomatosis on a cinnamon- and benzoate-free diet by White A1, Nunes C, Escudier M, Lomer MC, Barnard K, Shirlaw P, Challacombe SJ, Sanderson JD.(PubMed)

Herbal Coltsfoot(Tussilago farfara) Protects the Lung Against Tuberculosis (TB)

The lung is a vital organ located near the backbone on either side of the heart with major functions to inhale oxygen from the air to the bloodstream that nourishes the body cells and exhale carbon dioxide from the bloodstream.

Other functions of the lung are to maintain the right levels of pH, filter out blood clots, protect the heart against shock, infection, and speech.

Tuberculosis (TB) is a contagious disease caused by bacteria called Mycobacterium tuberculosis.

The bacteria attacked the lung tissue, leading to the significantly reduced function of the lung in the inhaling and exhaling.

The disease is also found to cause major damage to other parts of the body.

According to statistics, 25% of the world's population is infected with TB. In 2016, 10.4 million people around the world became sick with the disease-inducing the death of 1.7 million people.

The most common signs and symptoms of TB are associated with reduced lung function, including coughing that lasts a long period of time, coughing up blood, chest pain, particularly in breathing or coughing, fatigue, fever, night sweats, and chills.

Some patients may also experience symptoms of unintended weight loss.

Conventionally, the length of treatment of TB depending on the severity of the disease takes longer compared to other infections with at least six months of antibiotics intake, including Isoniazid, Rifampin (Rifadin, Rimactane) and Ethambutol (Myambutol).

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound that processes antitubercular activity, researchers examined the effect of Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis.

In Mycobacterium tuberculosis H37Rv, according to the tested analysis, the ethyl acetate extract of Tussilago farfara displayed antitubercular activity with a MIC of 62.5 μg/mL.

The anti-tuberculosis property of Tussilago farfara against the Mycobacterium tuberculosis H37Rv was attributed to the compounds including mixture of β sitosterol/stigmasterol (4), trans-caffeic acid (7), kaempferol (8), quercetin (9), kaempferol-3-O-glucoside (10), loliolide (11), a (4:1) mixture of p-coumaric acid/4-hydroxybenzoic acid (12), p-coumaric acid (13). in the extract.

In compound comparison, the best anti-tuberculosis activity was observed in the p-coumaric acid (13) (MIC 31.3 μg/mL or 190.9 μM) alone and in mixture with 4-hydroxybenzoic acid (12) (MIC 62.5 μg/mL).

Based on the findings, researchers aid, "The above results provide for the first time some scientific evidence to support, to some extent, the ethnomedicinal use of Arctium lappa and Tussilago farfara as traditional antitubercular remedies.".

Taken altogether, coltsfoot may be considered a remedy for the treatment of tuberculosis, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents by Zhao J1, Evangelopoulos D2, Bhakta S2, Gray AI1, Seidel V. (PubMed)