The central system is the complex of nerve tissues including the brain and spinal cord with functions to respond to the integrating sensory information.
Neuroinflammation is a process of the immune system response to harmful pathogens that induced oxidative stress to the brain.
Neuroinflammation is also the inflammation of nervous tissue associated with the immune response in the first phase of infection including infection, traumatic brain injury, toxic metabolites, or autoimmunity.
Neurological disorders are class of diseases associated with the brain, the spinal cord including the nerves that connect them.
The most common diseases of neurological disorders are dementia, including ALS. PD, Alzheimer's disease, birth defects of the brain and spinal cord, brain injury and tumor.
Back pain associated with the related nerve damage is one of the common complaints in the US that send many patients to seek help from their doctor. Believe it or not, 80% of the US population will experience back pain at some time in their lives.
There is no single cause of neuro-dysfunction. Lifestyle, infections, genetics, and nutrition-related disease, environment, and physical injuries have been found to some major prevalent factors that induce the onset of neurological abnormalities.
Furthermore, neurological disorders have been found to facilitate psychological symptoms such as anxiety and depression and physical symptoms, depending totally on the neurons affected, including partial or complete paralysis muscle weakness seen on post-stroke patients, difficulty reading and writing and poor cognitive abilities such as patients with dementia.
According to the American Addiction Center, if you experience some of the below symptoms persistently, including headaches, blurry vision, persistent fatigue, changes in behavior, numbness in the legs or arms, changes in coordination or balance weakness, slurred speech and tremors, you should seek help from the professionals immediately, as these may be the first signs of neurological disorders.
Neurodegenerative diseases are the most common forms of low-grade chronic neuroinflammation, including Alzheimer's disease, vascular dementia, and dementia with Lewy bodies.
Dr. WEI-WEI CHEN, the lead scientist at the Xuzhou Central Hospital in the investigation of inflammatory cytokines and chronic neuroinflammation wrote, "Accordingly, pro-inflammatory cytokines are important in the pathophysiology of depression and dementia"
And, "These data suggest that the role of neuroinflammation in neurodegeneration must be fully elucidated, since pro-inflammatory agents, which are the causative effects of neuroinflammation, occur widely, particularly in the elderly in whom inflammatory mechanisms are linked to the pathogenesis of functional and mental impairments.".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for enhancing brain performance, researchers examined the ashwagandha effects on the neurons.
Epidemiologically, environmental stressors have been found to cause global concerns of the modern society, by rapidly increasing the incidence of a variety of pathological conditions including brain tumors, neurodegenerative & neuropsychiatric disorders.
Ashwagandha used in Indian traditional home medicine showed to process the anti-stress and remedial potential for the treatment of aging and neurodegenerative pathologies, including the environmental toxins.
Furthermore, Ashwagandha extracts and its active principles also exerted the underlying molecular mechanism(s) that inhibits the brain pathologies through the herb nootropic potency.
Moreover, in examing the Ashwagandha leaf extracts effects, researchers found that the Ashwagandha inhibited neuroblastoma and glioma cell initiation, and reversal of Alzheimer's and Parkinson's pathologies, protection against environmental neurotoxins and enhancement of memory.
Based on the findings, researchers said, "ashwagandha supplementation is associated with significant increases in muscle mass and strength and suggests that ashwagandha supplementation may be useful in conjunction with a resistance training program".
Taken altogether, Ashwagandha may be considered a functional herb that increases body mass and strength in resistance training, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Nootropic potential of Ashwagandha leaves: Beyond traditional root extracts by Wadhwa R1, Konar A1, Kaul SC. (PubMed)
(2) Role of neuroinflammation in neurodegenerative diseases (Review) by Chen WW1, Zhang X1, Huang WJ. (PubMed)
Sunday, December 22, 2019
Topical Arnica Gel, The Potent Herbal Product Which Alleviates Symptoms and Treatment of Osteoarthritis
Herbal Arnica may have a therapeutic potential in ameliorating the symptoms and treatment of osteoarthritis, some scientists suggested.
The results of this investigation were carried out in the form of studies by some respectable institutes such as Rheumatology Clinic Sweden, and Valens Clinic for Rheumatism published online medical literature.
Arthritis is a chronic condition characterized by severe inflammatory pain and stiffness of the joints. affecting over 1.3 million Americans and as much as 1% of the worldwide population, according to statistics. The disease induced an average direct cost of about $2,800 per patient annually.
Osteoarthritis is a type of degenerative joint disease or “wear and tear” arthritis, affecting the joint commonly.
The exact causes of osteoarthritis are unknown. Researchers do not understand why, people with the same health and risk conditions, are susceptible to the onset of the disease while others do not.
However, researchers do know that certain risk factors are associated with the early onset of the disease, including age, family history, gender, injured from the past that did not heal properly, such as torn cartilage, dislocated joints, ligament injuries, occupations and overweight.
Some scientists also suggested that mutation of genes involved develop cartilage are also having a strong implication in inducing the early onset of the disease.
Dr.Mercedes Fernández-Moreno, the lead authors in the expression of Genetics in Osteoarthritis, wrote, "The genetic bases of this disease do not follow the typical patterns of Mendelian inheritance and probably they are related to alterations in multiple genes. The identification of a high number of candidate genes to confer susceptibility to the development of the osteoarthritis shows the complex nature of this disease".
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the randomized, double-blind study to compare the effective of topical preparation of arnica(50 g tincture/100 g, DER 1:20), and ibuprofen (5%) and in 204 patients, to ascertain differences in pain relief and hand function after 21 days' treatment, scientists showed that topical Arnica exerts a similar effect as of ibuprofen (5%) in pain and hand function improvements, or in any secondary endpoints.
There were no differences between the two groups in pain relief and improvement of hand stiffness.
However, compared to 2 groups, researchers found that adverse effects were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica.
These results suggested that Arnica's topical preparation is compatible with those of ibuprofen for the treatment of patients with osteoarthritis, particularly in the patients with hand's osteoarthritis.
Further analysis of the safety and efficacy of an Arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (OA) of the knee, after 3 and weeks of application, researchers indicated that
* All groups (treatment with 3 and 6 weeks) display a significant improvement of scores on the pain, stiffness, and function subscales.
* The topical application also shows significant reductions at these time points.
* Total scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) are decreased substantially in all patients.
* According to the returned questionnaire, 69 patients (87%) rate the tolerability of the topical gel as "good" or "fairly good,"
However, the overall local adverse-event rate is 7.6% included only one allergic reaction.
Although the topical gel may be effective, it has certain limitations as only patients with mild to moderate OA of the knee were included in the study.
The above differentiation of topical Arnica gel was supported by the publication lead by Dr. Morris M, in the investigation of the efficacy of a homeopathic complex included Arnica montana, Bryonia alba, Causticum, Kalmia latifolia, Rhus Toxicodendron, and Calcarea fluorica. in combination with physiotherapy in treating chronic lower back pain (CLBP) due to OA.
In a 6-wk, randomized, double-blind, placebo-controlled pilot study took place in a private physiotherapy practice in Gauteng, South Africa of a total of 30 males and females, aged 45-75 y, who were receiving physiotherapy treatment for OA of the lumbar spine from a therapist in private practice, according to the observation of the visual analog scale (VAS) for pain. Secondary outcome measures, the complex application showed incredible effectiveness in reduced pain, promoted daily functioning, and range of motion (ROM) of the lumbar spine in compared to placebo.
After taking into account other co and confounders, Dr. Morris M, the lead scientist said, "homeopathic complex, together with physiotherapy, can significantly improve symptoms associated with CLBP due to OA" and "(but) the study was too small to be conclusive".
Taken together, topical Arnica gel with a certain concentration may be considered a functional herb for alleviated symptoms and treatment of osteoarthritis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study by Widrig R1, Suter A, Saller R, Melzer J.(PubMed)
(2) Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial by Knuesel O1, Weber M, Suter A.(PubMed)
(3) Physiotherapy and a Homeopathic Complex for Chronic Low-back Pain Due to Osteoarthritis: A Randomized, Controlled Pilot Study by Morris M, Pellow J, Solomon EM, Tsele-Tebakang T.(PubMed)
(4) Genetics in Osteoarthritis by Mercedes Fernández-Moreno, Ignacio Rego, Vanessa Carreira-Garcia, and Francisco J Blanco. (PMC)
The results of this investigation were carried out in the form of studies by some respectable institutes such as Rheumatology Clinic Sweden, and Valens Clinic for Rheumatism published online medical literature.
Arthritis is a chronic condition characterized by severe inflammatory pain and stiffness of the joints. affecting over 1.3 million Americans and as much as 1% of the worldwide population, according to statistics. The disease induced an average direct cost of about $2,800 per patient annually.
Osteoarthritis is a type of degenerative joint disease or “wear and tear” arthritis, affecting the joint commonly.
The exact causes of osteoarthritis are unknown. Researchers do not understand why, people with the same health and risk conditions, are susceptible to the onset of the disease while others do not.
However, researchers do know that certain risk factors are associated with the early onset of the disease, including age, family history, gender, injured from the past that did not heal properly, such as torn cartilage, dislocated joints, ligament injuries, occupations and overweight.
Some scientists also suggested that mutation of genes involved develop cartilage are also having a strong implication in inducing the early onset of the disease.
Dr.Mercedes Fernández-Moreno, the lead authors in the expression of Genetics in Osteoarthritis, wrote, "The genetic bases of this disease do not follow the typical patterns of Mendelian inheritance and probably they are related to alterations in multiple genes. The identification of a high number of candidate genes to confer susceptibility to the development of the osteoarthritis shows the complex nature of this disease".
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the randomized, double-blind study to compare the effective of topical preparation of arnica(50 g tincture/100 g, DER 1:20), and ibuprofen (5%) and in 204 patients, to ascertain differences in pain relief and hand function after 21 days' treatment, scientists showed that topical Arnica exerts a similar effect as of ibuprofen (5%) in pain and hand function improvements, or in any secondary endpoints.
There were no differences between the two groups in pain relief and improvement of hand stiffness.
However, compared to 2 groups, researchers found that adverse effects were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica.
These results suggested that Arnica's topical preparation is compatible with those of ibuprofen for the treatment of patients with osteoarthritis, particularly in the patients with hand's osteoarthritis.
Further analysis of the safety and efficacy of an Arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (OA) of the knee, after 3 and weeks of application, researchers indicated that
* All groups (treatment with 3 and 6 weeks) display a significant improvement of scores on the pain, stiffness, and function subscales.
* The topical application also shows significant reductions at these time points.
* Total scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) are decreased substantially in all patients.
* According to the returned questionnaire, 69 patients (87%) rate the tolerability of the topical gel as "good" or "fairly good,"
However, the overall local adverse-event rate is 7.6% included only one allergic reaction.
Although the topical gel may be effective, it has certain limitations as only patients with mild to moderate OA of the knee were included in the study.
The above differentiation of topical Arnica gel was supported by the publication lead by Dr. Morris M, in the investigation of the efficacy of a homeopathic complex included Arnica montana, Bryonia alba, Causticum, Kalmia latifolia, Rhus Toxicodendron, and Calcarea fluorica. in combination with physiotherapy in treating chronic lower back pain (CLBP) due to OA.
In a 6-wk, randomized, double-blind, placebo-controlled pilot study took place in a private physiotherapy practice in Gauteng, South Africa of a total of 30 males and females, aged 45-75 y, who were receiving physiotherapy treatment for OA of the lumbar spine from a therapist in private practice, according to the observation of the visual analog scale (VAS) for pain. Secondary outcome measures, the complex application showed incredible effectiveness in reduced pain, promoted daily functioning, and range of motion (ROM) of the lumbar spine in compared to placebo.
After taking into account other co and confounders, Dr. Morris M, the lead scientist said, "homeopathic complex, together with physiotherapy, can significantly improve symptoms associated with CLBP due to OA" and "(but) the study was too small to be conclusive".
Taken together, topical Arnica gel with a certain concentration may be considered a functional herb for alleviated symptoms and treatment of osteoarthritis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study by Widrig R1, Suter A, Saller R, Melzer J.(PubMed)
(2) Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial by Knuesel O1, Weber M, Suter A.(PubMed)
(3) Physiotherapy and a Homeopathic Complex for Chronic Low-back Pain Due to Osteoarthritis: A Randomized, Controlled Pilot Study by Morris M, Pellow J, Solomon EM, Tsele-Tebakang T.(PubMed)
(4) Genetics in Osteoarthritis by Mercedes Fernández-Moreno, Ignacio Rego, Vanessa Carreira-Garcia, and Francisco J Blanco. (PMC)
Aloe Vera, The Functional Herb Which Normalizes High Blood Pressure Quickly With No Adverse Effects
Good news to people with hypertension, Aloe Vera may be a potential and therapeutic agent for lowering high blood pressure a renowned University study suggested.
Hypertension is a condition of abnormally high blood pressure, leading to symptoms of headaches, shortness of breath or nosebleeds......
Hypertension is a measurement with home systolic/ diastolic BP > or = 135/85 mmHg.
According to statistics, the prevalence of hypertension affects over 39.4% for men and 29.3% for women in the Western World.
Prolong untreated hypertension is found to induce complications of strokes, heart attacks, heart failure, or kidney disease.
Some researchers suggested that patients who are actively in modulated daily high blood pressure may be benefits from reduced risk of stroke by 35%, heart attack by 20%, and heart failure by 50%.
According to the WHO-based Healthy Diet Indicator (HDI), the American Heart Association 2006 Diet and Lifestyle Recommendations(4),
* The prevalence of untreated hypertension and treated hypertension was 22.4% and 8.5%.
* Patients with untreated hypertension had significantly lower HDI and AI-84 scores compared with non-hypertension.
* After adjusting for age, energy intake, smoking habit, alcohol drinking, physical activity and salt intake, a low adherence to HDI and a lowest quartile of AI-84 score were associated with a significantly higher prevalence of untreated hypertension, with an OR of 3.33 (95% CI 1.39 to 7.94, p=0.007) and 2.23 (1.09 to 4.53, p=0.027), respectively.
These results are agreed to a general and popular belief that an unhealthy diet plays an important role in the induction of high blood pressure. Furthermore, the lower dietary quality was associated with an increased prevalence of untreated hypertension.
People who eat more fruits and vegetables compared to average daily intake are associated with a significantly lower risk of hypertension.
Dr. Utsugi MT in the comparison of fruits and vegetable intake daily said, "the highest-tertile consumptions of fruits, vegetables, potassium, and vitamin C were associated with a significantly lower risk of hypertension (45%, 38%, 46%, and 43% lower risk of home hypertension, respectively(5)".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to enormous health benefits. Aloe vera has also been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol,
According to the Hamdard University, aloeemodin, aloin A, a chemical compound found in Aloe Vera showed to express hypotensive effects by lower mean arterial blood pressure by 26 %, 52 %, and 79 % in the corresponding doses of 0.5, 1, and 3 mg/kg in an animal study.
Dr. Saleem R, the lead author of the study suggested that Aloeemodin has emerged as a potent hypotensive agent in the current pharmacological investigation.
In a total of In a double-blind, placebo-controlled, crossover study, healthy, Aloe-emodin, another major chemical compound\ inhibited vascular smooth muscle stiffness, a condition in the development of hypertension, involved cell in support structural and biochemical and the interior surface of blood vessels.
In hypertension, increased large-artery stiffness is partly due to the intrinsic mechanical properties of vascular smooth muscle cells.
More importantly, smooth muscle cells derived from hypertensive and control rats study, treatment of Aloe-emodin also significantly reduced hypertension by improving the elastic value of vascular smooth muscle cell, through it effects on vascular smooth muscle cell cytoskeletal proteins in the regulated function of cell division.
Other researchers suggested that the antihypertensive properties of Aloe-emodin may be a result of inhibition of tonic tension and regulated apoptosis, pro- and anti-apoptotic activities on vascular smooth muscle cells.
With all the information collected, Aloe Vera may have an antihypertensive effect in regulated protein in cell production on vascular smooth muscle which is the main cause of high blood pressure, but more precise understanding may be necessary to reassess this pharmaceutical value.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Biography
Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Hypotensive effect of chemical constituents from Aloe barbadensis by Saleem R1, Faizi S, Siddiqui BS, Ahmed M, Hussain SA, Qazi A, Dar A, Ahmad SI, Qazi MH, Akhtar S, Hasnain SN.(PubMed)
(2) Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension by Sehgel NL1, Zhu Y, Sun Z, Trzeciakowski JP, Hong Z, Hunter WC, Vatner DE, Meininger GA, Vatner SF.(PubMed)
(3) Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta by Lim KM1, Kwon JH, Kim K, Noh JY, Kang S, Park JM, Lee MY, Bae ON, Chung JH.(PubMed)
(4) Diet quality and adherence to a healthy diet in Japanese male workers with untreated hypertension by Kanauchi M1, Kanauchi K(PubMed)
(5) Fruit and vegetable consumption and the risk of hypertension determined by self measurement of blood pressure at home: the Ohasama study by Utsugi MT1, Ohkubo T, Kikuya M, Kurimoto A, Sato RI, Suzuki K, Metoki H, Hara A, Tsubono Y, Imai(PubMed)
Hypertension is a condition of abnormally high blood pressure, leading to symptoms of headaches, shortness of breath or nosebleeds......
Hypertension is a measurement with home systolic/ diastolic BP > or = 135/85 mmHg.
According to statistics, the prevalence of hypertension affects over 39.4% for men and 29.3% for women in the Western World.
Prolong untreated hypertension is found to induce complications of strokes, heart attacks, heart failure, or kidney disease.
Some researchers suggested that patients who are actively in modulated daily high blood pressure may be benefits from reduced risk of stroke by 35%, heart attack by 20%, and heart failure by 50%.
According to the WHO-based Healthy Diet Indicator (HDI), the American Heart Association 2006 Diet and Lifestyle Recommendations(4),
* The prevalence of untreated hypertension and treated hypertension was 22.4% and 8.5%.
* Patients with untreated hypertension had significantly lower HDI and AI-84 scores compared with non-hypertension.
* After adjusting for age, energy intake, smoking habit, alcohol drinking, physical activity and salt intake, a low adherence to HDI and a lowest quartile of AI-84 score were associated with a significantly higher prevalence of untreated hypertension, with an OR of 3.33 (95% CI 1.39 to 7.94, p=0.007) and 2.23 (1.09 to 4.53, p=0.027), respectively.
These results are agreed to a general and popular belief that an unhealthy diet plays an important role in the induction of high blood pressure. Furthermore, the lower dietary quality was associated with an increased prevalence of untreated hypertension.
People who eat more fruits and vegetables compared to average daily intake are associated with a significantly lower risk of hypertension.
Dr. Utsugi MT in the comparison of fruits and vegetable intake daily said, "the highest-tertile consumptions of fruits, vegetables, potassium, and vitamin C were associated with a significantly lower risk of hypertension (45%, 38%, 46%, and 43% lower risk of home hypertension, respectively(5)".
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to enormous health benefits. Aloe vera has also been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol,
According to the Hamdard University, aloeemodin, aloin A, a chemical compound found in Aloe Vera showed to express hypotensive effects by lower mean arterial blood pressure by 26 %, 52 %, and 79 % in the corresponding doses of 0.5, 1, and 3 mg/kg in an animal study.
Dr. Saleem R, the lead author of the study suggested that Aloeemodin has emerged as a potent hypotensive agent in the current pharmacological investigation.
In a total of In a double-blind, placebo-controlled, crossover study, healthy, Aloe-emodin, another major chemical compound\ inhibited vascular smooth muscle stiffness, a condition in the development of hypertension, involved cell in support structural and biochemical and the interior surface of blood vessels.
In hypertension, increased large-artery stiffness is partly due to the intrinsic mechanical properties of vascular smooth muscle cells.
More importantly, smooth muscle cells derived from hypertensive and control rats study, treatment of Aloe-emodin also significantly reduced hypertension by improving the elastic value of vascular smooth muscle cell, through it effects on vascular smooth muscle cell cytoskeletal proteins in the regulated function of cell division.
Other researchers suggested that the antihypertensive properties of Aloe-emodin may be a result of inhibition of tonic tension and regulated apoptosis, pro- and anti-apoptotic activities on vascular smooth muscle cells.
With all the information collected, Aloe Vera may have an antihypertensive effect in regulated protein in cell production on vascular smooth muscle which is the main cause of high blood pressure, but more precise understanding may be necessary to reassess this pharmaceutical value.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Biography
Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Hypotensive effect of chemical constituents from Aloe barbadensis by Saleem R1, Faizi S, Siddiqui BS, Ahmed M, Hussain SA, Qazi A, Dar A, Ahmad SI, Qazi MH, Akhtar S, Hasnain SN.(PubMed)
(2) Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension by Sehgel NL1, Zhu Y, Sun Z, Trzeciakowski JP, Hong Z, Hunter WC, Vatner DE, Meininger GA, Vatner SF.(PubMed)
(3) Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta by Lim KM1, Kwon JH, Kim K, Noh JY, Kang S, Park JM, Lee MY, Bae ON, Chung JH.(PubMed)
(4) Diet quality and adherence to a healthy diet in Japanese male workers with untreated hypertension by Kanauchi M1, Kanauchi K(PubMed)
(5) Fruit and vegetable consumption and the risk of hypertension determined by self measurement of blood pressure at home: the Ohasama study by Utsugi MT1, Ohkubo T, Kikuya M, Kurimoto A, Sato RI, Suzuki K, Metoki H, Hara A, Tsubono Y, Imai(PubMed)
Herbal Artichoke Improves Liver Functioning
On seeking natural therapy with no side effects, scientists may have found a herbal remedy for improvement of liver functioning, according to studies.
The liver function plays a critical role in filtering blood comes from the intestinal before passing them to other organs and tissues. The reddish-brown organ also detoxes toxic chemicals and metabolizes medicine and secrete bile to the intestine for breaking down food and absorbing nutrients.
Additionally, the liver is found to process the ability to secrete proteins such as albumin, fibrinogens, and apolipoproteins into the blood for the regulation of the oncotic pressure, blood clotting, and lipoprotein metabolism, respectively.
There are many factors can disrupt the liver function including viral infection, alcohol use or obesity, leading to scar formation in the liver tissue.
Long-term untreated chronic liver infection that causes the replacement of normal liver tissue by scar tissues eventually lead to cirrhosis, a non-reversible, dangerous condition that can lead to liver failure and cancer.
At the early stage of liver disease, most patients are asymptomatic. However, as the disease progresses patients may experience unspecific symptoms of loss of appetite, fatigue, general malaise, gastrointestinal discomforts or weight loss.
At the advanced stage severe on the right side of the abdomen, jaundice, pale stool, harden urine color, spiderlike blood vessels on the skin, redness in the palms of the hands.
Liver damage at this stage may cause loss of period in some women and loss of sex drive, breast enlargement or testicular atrophy in men.
In the severe case, patients also have symptoms of confusion, drowsiness and slurred speech.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On finding a natural compound for enhancing the liver function, researchers at the Laboratoire de pharmacology examined the liver-protective effects of artichoke (Cynara scolymus) leaf extract.
Injection of artichoke extract improved the liver function in the production of bile and liver lipid production and lipid recycling by lowering blood cholesterol.
In animal models, the liquid extracts of the roots and leaves of artichoke also found to demonstrate an ability to protect the liver, possibly in enhancing liver cells regenerate.
Furthermore, the administration of artichoke extract reduced the risk of cardiovascular disease by lowering risk factors associated with liver function in regulating cholesterol and triglycerides.
According to the therapeutic effects of artichoke on biochemical and liver biomarkers in patients with nonalcoholic steatohepatitis (NASH), artichoke improved the function of the liver by improving liver enzymes which were significantly reduced in NASH.
Taken altogether, artichoke may have a strong implication in improving the liver function in many aspects, pending to the validation of larger sample size and multicenter studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits by Ben Salem M1, Affes H2,3, Ksouda K1, Dhouibi R1, Sahnoun Z1, Hammami S1, Zeghal KM. (PubMed)
The liver function plays a critical role in filtering blood comes from the intestinal before passing them to other organs and tissues. The reddish-brown organ also detoxes toxic chemicals and metabolizes medicine and secrete bile to the intestine for breaking down food and absorbing nutrients.
Additionally, the liver is found to process the ability to secrete proteins such as albumin, fibrinogens, and apolipoproteins into the blood for the regulation of the oncotic pressure, blood clotting, and lipoprotein metabolism, respectively.
There are many factors can disrupt the liver function including viral infection, alcohol use or obesity, leading to scar formation in the liver tissue.
Long-term untreated chronic liver infection that causes the replacement of normal liver tissue by scar tissues eventually lead to cirrhosis, a non-reversible, dangerous condition that can lead to liver failure and cancer.
At the early stage of liver disease, most patients are asymptomatic. However, as the disease progresses patients may experience unspecific symptoms of loss of appetite, fatigue, general malaise, gastrointestinal discomforts or weight loss.
At the advanced stage severe on the right side of the abdomen, jaundice, pale stool, harden urine color, spiderlike blood vessels on the skin, redness in the palms of the hands.
Liver damage at this stage may cause loss of period in some women and loss of sex drive, breast enlargement or testicular atrophy in men.
In the severe case, patients also have symptoms of confusion, drowsiness and slurred speech.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On finding a natural compound for enhancing the liver function, researchers at the Laboratoire de pharmacology examined the liver-protective effects of artichoke (Cynara scolymus) leaf extract.
Injection of artichoke extract improved the liver function in the production of bile and liver lipid production and lipid recycling by lowering blood cholesterol.
In animal models, the liquid extracts of the roots and leaves of artichoke also found to demonstrate an ability to protect the liver, possibly in enhancing liver cells regenerate.
Furthermore, the administration of artichoke extract reduced the risk of cardiovascular disease by lowering risk factors associated with liver function in regulating cholesterol and triglycerides.
According to the therapeutic effects of artichoke on biochemical and liver biomarkers in patients with nonalcoholic steatohepatitis (NASH), artichoke improved the function of the liver by improving liver enzymes which were significantly reduced in NASH.
Taken altogether, artichoke may have a strong implication in improving the liver function in many aspects, pending to the validation of larger sample size and multicenter studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits by Ben Salem M1, Affes H2,3, Ksouda K1, Dhouibi R1, Sahnoun Z1, Hammami S1, Zeghal KM. (PubMed)
Andrographis, A Chemotherapeutic Agent for Treatment of Breast Cancer
Herbal Andrographis paniculata may be used as a therapeutic agent for treatment and drug resistance breast cancer, a study by the renowned institute suggested.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...
Breast cancer (malignant breast neoplasm) is a condition characterized by abnormal cells grow in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma).
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
According to the joint study led by the University of Kalyani, Andrographolide showed significant inhibition of MDA-MB-231 breast cancer cell proliferation in a time- and concentration-dependent manner.
The study also found that the inhibition of breast cancer cell line proliferation with no effect on normal breast epithelial cells, through reduced oxygen species (ROS) production and increased the population of apoptotic cells.
Other, in the study of the cytotoxic effect of a chemical compound, 14-Deoxy-11,12-didehydroandrographolide (14-DDA), a major diterpenoid isolated from Andrographis paniculata (Burm.f.) Nees, application of the products suppressed the T-47D breast carcinoma cells caused cytotoxicity and elicited a non-apoptotic cell death.
Also in the MDA-MB-231 breast cancer cell, Andrographolide, a major chemical compound found in Andrographis exhibited strong anti-breast cancer cell growth activities in regulating breast cancer cell proliferation, survival and progression, and breast cancer metastasis through various mechanisms involved pro-inflammatory pathways.
Taking together, there is no doubt that Andrographis may be used as a possible chemopreventive and chemotherapeutic agent for human breast cancers. But a large amount of intake should only be prescribed by an herbalist.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Cytotoxicity and cell cycle arrest induced by andrographolide lead to programmed cell death of MDA-MB-231 breast cancer cell line by Banerjee M1,2, Chattopadhyay S2, Choudhuri T3, Bera R2, Kumar S2, Chakraborty B2, Mukherjee SK4.(PubMed)
(2) 14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells by Tan HK1, Muhammad TS2, Tan ML3.(PubMed)
(3) Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression by Zhai Z1, Qu X1, Li H1, Ouyang Z1, Yan W2, Liu G3, Liu X1, Fan Q1, Tang T1, Dai K1, Qin A1.(PubMed)
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,...
Breast cancer (malignant breast neoplasm) is a condition characterized by abnormal cells grow in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma).
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
According to the joint study led by the University of Kalyani, Andrographolide showed significant inhibition of MDA-MB-231 breast cancer cell proliferation in a time- and concentration-dependent manner.
The study also found that the inhibition of breast cancer cell line proliferation with no effect on normal breast epithelial cells, through reduced oxygen species (ROS) production and increased the population of apoptotic cells.
Other, in the study of the cytotoxic effect of a chemical compound, 14-Deoxy-11,12-didehydroandrographolide (14-DDA), a major diterpenoid isolated from Andrographis paniculata (Burm.f.) Nees, application of the products suppressed the T-47D breast carcinoma cells caused cytotoxicity and elicited a non-apoptotic cell death.
Also in the MDA-MB-231 breast cancer cell, Andrographolide, a major chemical compound found in Andrographis exhibited strong anti-breast cancer cell growth activities in regulating breast cancer cell proliferation, survival and progression, and breast cancer metastasis through various mechanisms involved pro-inflammatory pathways.
Taking together, there is no doubt that Andrographis may be used as a possible chemopreventive and chemotherapeutic agent for human breast cancers. But a large amount of intake should only be prescribed by an herbalist.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Cytotoxicity and cell cycle arrest induced by andrographolide lead to programmed cell death of MDA-MB-231 breast cancer cell line by Banerjee M1,2, Chattopadhyay S2, Choudhuri T3, Bera R2, Kumar S2, Chakraborty B2, Mukherjee SK4.(PubMed)
(2) 14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells by Tan HK1, Muhammad TS2, Tan ML3.(PubMed)
(3) Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression by Zhai Z1, Qu X1, Li H1, Ouyang Z1, Yan W2, Liu G3, Liu X1, Fan Q1, Tang T1, Dai K1, Qin A1.(PubMed)
Saturday, December 21, 2019
Bilberry Cuts Off the Energy Supply to Cancers, Studies Found
Bilberry may process a unique function in blocking the formation of the new blood vessels to fuel tumor growth, according to studies.
Angiogenesis is the development of new blood vessels from the existing vasculature. The process has occurred throughout life in humans in forms of health and disease.
Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients,
In a tumor, the availability of nutrients is limited, therefore, for the tumor to survive and to grow continuously, the tumor cells induce the formation a new blood supply from the preexisting vasculature by stimulating the protein associated with the pro-angiogenesis and facilitation of angiogenesis, such as vascular endothelial growth factor.
In other words, if we can cut off the blood vessels that provide nutrients to the tumor, we may cure cancers.
Dr. Adair TH, the lead scientists in the investigation of the angiogenesis in diseases and cancer said, "Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing. Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases".
And, "Capillaries grow and regress in healthy tissues according to functional dem bands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss.
The results strongly suggested that by allowing or blocking the growth of new blood vessels, angiogenesis may be used as a primary target for the treatment of chronic diseases and cancers
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding a natural compound that blocks the progression of cancer examined the anti-angiogenic activity of berry anthocyanins.
Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seeds, and strawberry) included in the study were analyzed the anti-angiogenic (the ability to reduce unwanted growth of blood vessels, which can lead to varicose veins and tumor formation) properties.
Formula OptiBerry IH141, including all berries used in the study, demonstrated superior anti-angiogenic properties compared to the other combinations tested.
OptiBerry significantly inhibited free radical and proinflammatory cytokines in the expression of VEGF (Vascular Endothelial Growth Factor) associated with the formation of the new blood vessels.
According to the Matrigel assay using human microvascular endothelial cells, OptiBerry reduced the new blood vessel formation by impairing angiogenesis.
Furthermore, endothelioma cells pretreated with OptiBerry showed a diminished ability to form hemangioma and markedly decreased tumor growth by more than 50% through its anti-angiogenic, and anti-carcinogenic properties.
In order to reveal more information about berries anti-angiogenic activity to prevent and treat cancer, researchers investigated the six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seed, and strawberry) and a grape seed proanthocyanidin extract (GSPE) against the formation of new blood vessels for cancer proliferation.
Wild bilberry and blueberry extracts possessed the highest antioxidant activity observed by the ORAC values compared to other berries.
In other words, wild bilberry and blueberry extracts inhibited the overexpression of free radicals and proinflammatory cytokines in stimulating the production of VEGF (Vascular Endothelial Growth Factor) in enhancing angiogenesis.
Interestingly, these activities of wild bilberry and blueberry extracts were not shared by other antioxidants such as alpha-tocopherol or GSPE but were commonly shared by pure flavonoids.
Taken altogether, bilberry used alone or combined with other berries may be considered functional remedies for the prevention of angiogenesis and treatment of cancer cells proliferation by stimulating the formation of a new blood vessel, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula by Bagchi D1, Sen CK, Bagchi M, Atalay M. (PubMed)
(2) Anti-angiogenic property of edible berries by Roy S1, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. (PubMed)
(3) Chapter 1Overview of Angiogenesis by Adair TH, Montani JP.. (NCBI)
Angiogenesis is the development of new blood vessels from the existing vasculature. The process has occurred throughout life in humans in forms of health and disease.
Normal angiogenesis ensures that developing or healing tissues receive an adequate supply of nutrients,
In a tumor, the availability of nutrients is limited, therefore, for the tumor to survive and to grow continuously, the tumor cells induce the formation a new blood supply from the preexisting vasculature by stimulating the protein associated with the pro-angiogenesis and facilitation of angiogenesis, such as vascular endothelial growth factor.
In other words, if we can cut off the blood vessels that provide nutrients to the tumor, we may cure cancers.
Dr. Adair TH, the lead scientists in the investigation of the angiogenesis in diseases and cancer said, "Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing. Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases".
And, "Capillaries grow and regress in healthy tissues according to functional dem bands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss.
The results strongly suggested that by allowing or blocking the growth of new blood vessels, angiogenesis may be used as a primary target for the treatment of chronic diseases and cancers
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The herbal plant has been used as foods and herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding a natural compound that blocks the progression of cancer examined the anti-angiogenic activity of berry anthocyanins.
Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seeds, and strawberry) included in the study were analyzed the anti-angiogenic (the ability to reduce unwanted growth of blood vessels, which can lead to varicose veins and tumor formation) properties.
Formula OptiBerry IH141, including all berries used in the study, demonstrated superior anti-angiogenic properties compared to the other combinations tested.
OptiBerry significantly inhibited free radical and proinflammatory cytokines in the expression of VEGF (Vascular Endothelial Growth Factor) associated with the formation of the new blood vessels.
According to the Matrigel assay using human microvascular endothelial cells, OptiBerry reduced the new blood vessel formation by impairing angiogenesis.
Furthermore, endothelioma cells pretreated with OptiBerry showed a diminished ability to form hemangioma and markedly decreased tumor growth by more than 50% through its anti-angiogenic, and anti-carcinogenic properties.
In order to reveal more information about berries anti-angiogenic activity to prevent and treat cancer, researchers investigated the six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seed, and strawberry) and a grape seed proanthocyanidin extract (GSPE) against the formation of new blood vessels for cancer proliferation.
Wild bilberry and blueberry extracts possessed the highest antioxidant activity observed by the ORAC values compared to other berries.
In other words, wild bilberry and blueberry extracts inhibited the overexpression of free radicals and proinflammatory cytokines in stimulating the production of VEGF (Vascular Endothelial Growth Factor) in enhancing angiogenesis.
Interestingly, these activities of wild bilberry and blueberry extracts were not shared by other antioxidants such as alpha-tocopherol or GSPE but were commonly shared by pure flavonoids.
Taken altogether, bilberry used alone or combined with other berries may be considered functional remedies for the prevention of angiogenesis and treatment of cancer cells proliferation by stimulating the formation of a new blood vessel, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula by Bagchi D1, Sen CK, Bagchi M, Atalay M. (PubMed)
(2) Anti-angiogenic property of edible berries by Roy S1, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. (PubMed)
(3) Chapter 1Overview of Angiogenesis by Adair TH, Montani JP.. (NCBI)
Andrographis in Accelerated Wound Healing with Lesser Scar
Andrographis paniculata is also known as Andrographis, is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka, used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia,.. .....
Wound healing is a natural response to restore injured tissues.
Andrographis paniculata leaf showed to process a significant wound healing effect in restoring injured tissues, a mentioned institute suggested.
According to the Universiti Teknologi MARA, the topical application of Andrographis paniculata exerted a strong effect on the rate of wound enclosure with markedly less scar width and contained large amounts of fibroblast proliferation.
In a study of the wound created in four groups of rats in the posterior neck region. Blank placebo applied topically to the wounds of Group 1 and Groups 2 and 3 dressed with placebo containing 5% and 10% extracts of A. paniculata, groups treated with topical showed a rate of wound healing significantly accelerated in the wound dressed compared to the placebo group.
The wound healing is also increased collagen and less formation of new blood vessels with the absence of inflammatory cells.
Another study, in the evaluation of the effects of andrographis wound healing activity of Swiss Wistar strain rats with either sex with topical application, 2%w/w ointment of ethanol extract and petroleum ether extract prepared in 2% w/w PEG-4000 in comparison to the left untreated control group, treatment groups showed a faster rate of complete healing in day 12 after topical application with wound contractions in petroleum ether extract, ethanolic extract was at 10.17 and 16.33, respectively.
Dr. Arnabaditya Mohanty, the lead authors in the joint study said, "Andrographis paniculate ethanolic extract possesses better wound healing property in comparison to control and also with petroleum ether extract".
Taking together, topical application of Andrographis paniculata leaf and extract may be used as a wound-healing agent in accelerated restored injured tissues with lesser scar without induced adverse effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Effect of Andrographis paniculata leaf extract on wound healing in rats by Al-Bayaty FH1, Abdulla MA, Abu Hassan MI, Ali HM.(PubMed) and(University of Malaya)
(2) Preliminary Pytochemical Screening and Wound Healing Activity of Andrographis Peniculata by Arnabaditya Mohanty1 , Dusmanta Kumar Pradhan1 , Manas Ranjan Mishra1 , Jitendra Kumar Sahoo1 , Ashutosh Mishra *2, Bankim Chan(Journal of Chemical and Pharmaceutical Research)
Wound healing is a natural response to restore injured tissues.
Andrographis paniculata leaf showed to process a significant wound healing effect in restoring injured tissues, a mentioned institute suggested.
According to the Universiti Teknologi MARA, the topical application of Andrographis paniculata exerted a strong effect on the rate of wound enclosure with markedly less scar width and contained large amounts of fibroblast proliferation.
In a study of the wound created in four groups of rats in the posterior neck region. Blank placebo applied topically to the wounds of Group 1 and Groups 2 and 3 dressed with placebo containing 5% and 10% extracts of A. paniculata, groups treated with topical showed a rate of wound healing significantly accelerated in the wound dressed compared to the placebo group.
The wound healing is also increased collagen and less formation of new blood vessels with the absence of inflammatory cells.
Another study, in the evaluation of the effects of andrographis wound healing activity of Swiss Wistar strain rats with either sex with topical application, 2%w/w ointment of ethanol extract and petroleum ether extract prepared in 2% w/w PEG-4000 in comparison to the left untreated control group, treatment groups showed a faster rate of complete healing in day 12 after topical application with wound contractions in petroleum ether extract, ethanolic extract was at 10.17 and 16.33, respectively.
Dr. Arnabaditya Mohanty, the lead authors in the joint study said, "Andrographis paniculate ethanolic extract possesses better wound healing property in comparison to control and also with petroleum ether extract".
Taking together, topical application of Andrographis paniculata leaf and extract may be used as a wound-healing agent in accelerated restored injured tissues with lesser scar without induced adverse effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Effect of Andrographis paniculata leaf extract on wound healing in rats by Al-Bayaty FH1, Abdulla MA, Abu Hassan MI, Ali HM.(PubMed) and(University of Malaya)
(2) Preliminary Pytochemical Screening and Wound Healing Activity of Andrographis Peniculata by Arnabaditya Mohanty1 , Dusmanta Kumar Pradhan1 , Manas Ranjan Mishra1 , Jitendra Kumar Sahoo1 , Ashutosh Mishra *2, Bankim Chan(Journal of Chemical and Pharmaceutical Research)
Subscribe to:
Posts (Atom)