Skin aging is a natural process that can not be stopped. However, some people may look younger compared to their biological age.
According to the prominent oxidative stress theory, long-term accumulation of cell damage due to overexpression of free radicals in the skin can lead to early skin aging.
The joint study led by the University of Texas Health Science Center at San Antonio suggested, alterations in oxidative damage/stress also play a role in aging. Rodents with resistance to oxidative stress (and in some cases reduced oxidative damage to macromolecules) showed an increased lifespan, compared to oxidative stress control.
Some researchers suggested that genetic preposition may play a critical role in the promotion of delayed aging. Dr. Viviana I Pérez, the lead scientist in the study of free radical theory wrote, "Because only one (the deletion of the Sod1 gene) of the 18 genetic manipulations we studied had an effect on lifespan".
Regardless of free radical or other theories associated with the aging processes, there are many risk factors that can lead to reduced life span and delayed the skin aging process, even in people with a longevity gene.
In other words, long-term unhealthy lifestyles such as excessive alcohol drinking, substance abuse, smoking, physical inactivity not only can reduce the gene effect on longevity but also increase the risk of early skin aging and shorten the proposed life span.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and for the treatment of digestive disorders, abdominal pain gas and bloating, etc.
Researchers on the finding a natural therapeutic which processed antiaging property investigated the anti-age effect of a polyphenolic artichoke extract on endothelial cells.
Injection of the extract showed a significant anti-aging activity by exhibiting the important molecular markers responsible for the microcirculation and vasodilatation of endothelial cells, through its anti-inflammatory function, and protecting the lymphatic vessels from oxidative damage by ROS formation, and enhancing the cellular cohesion by reinforcing the tight junction complex.
In other words, the polyphenolic artichoke extracts exhibited an anti-age effect against the skin and subcutaneous tissue damage caused by overexpression of proinflammatory cytokines associated with the production of free radicals and depletion of antioxidant enzymes produced by the host.
The anti-aging efficacy was attributed to the combined activity of constituents found in the herbal medicine, including 87% of chlorogenic, 3,5-O-dicaffeoylquinic, and 1,5-O-dicaffeoylquinic acids.
Furthermore, polyphenolic artichoke extract improved the expression of genes involved in anti-aging mechanisms.
On human subjects, an artichoke extract cosmetic formulation also reduced 19.74% of roughness and enhanced 11.45% of elasticity, compared to a placebo cream.
Furthermore, in UVB-induced photoaging, researchers examined the antioxidant activity of Cynaropicrin (Cyn), a sesquiterpene lactone, and major bioactive phytochemicals in the artichoke.
Cynaropicrin (Cyn) attenuated UVB-induced oxidative stress by activating the AhR-Nrf2-Nqo1 pathway associated with the production of antioxidants and anti-inflammatory factors against oxidative stress.
In other words, in an anti-aging perspective, Cyn not only actively inhibited the generation of reactive oxygen species from keratinocytes irradiated with ultraviolet B (UVB), but also the production of proinflammatory cytokines such as interleukin 6 and tumor necrosis factor-α from UVB-treated keratinocytes.
Taken altogether, artichoke processed high amounts of bioactive compounds may be used as a functional antiaging remedy with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Artichoke Polyphenols Produce Skin Anti-Age Effects by Improving Endothelial Cell Integrity and Functionality by D'Antuono I1, Carola A2, Sena LM3, Linsalata V4, Cardinali A5, Logrieco AF6, Colucci MG7,8, Apone F. (PubMed)
(2) Cynaropicrin attenuates UVB-induced oxidative stress via the AhR-Nrf2-Nqo1 pathway byTakei K1, Hashimoto-Hachiya A1, Takahara M1, Tsuji G1, Nakahara T2, Furue M. (PubMed)
(3) Is the Oxidative Stress Theory of Aging Dead? by Viviana I Pérez,1,2 Alex Bokov,1,3 Holly Van Remmen,1,2,4,6 James Mele,4 Qitao Ran,1,2Yuji Ikeno,1,5,6 and Arlan Richardson. (PMC)
Saturday, January 4, 2020
Herbal Cascara Sagrada (Rhamnus purshiana), the Anti Viral Herbal Medicine
Herbal Cascara sagrada may be the next generation of the natural vaccine in reducing risk and treatment of viral infection, according to studies.imilar to
Similar to bacterial infection, both infections shared common characteristics by spreading through coughing and sneezing by and contact with infected people, especially through kissing and sex.
However, the virus may also cause infection by entering the body through wound and cut. Most viruses are killed in the acute phase of the infection.
During this phase, the immune system stimulates the constriction of blood vessels in speeding up the production of blood palette to cover the wound and production of inflammatory cytokines to the site of infection to fight off the bacterial and viral invasion.
The most common viruses that cause infection are hepatitis A, B, human papillomavirus (HPV) influenza. mumps, and rubella. People with a weakened immune system are susceptible to acute and chronic viral infections.
According to the article immune factor allows viral infections to become chronic by the University of Bonn, many viral diseases tend to become chronic, including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently".
Some researchers argued that the chronic infectious diseases may be a result of a weakened immune system which can not kill off the virus with the set period of time during the acute phase of infection, leading to the adaptation of the change, thus reducing the helper T cells in the secretion of inflammatory messengers and reduced function of the tumor necrosis factor in chronic infection compared to the acute phase of infection.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America.
The herbal bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.,
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
Researchers on finding a natural compound for the treatment of viral infection examined the effects of emodin, active ingredients from Rheum tanguticum (R. tanguticum, one of the Chinese Rhubarb) and Cascara Sagrada against HSV infection in tissue culture cells and in a mouse model.
Emodin displayed significant inhibition of the replication of HSV-1 and HSV-2 in cell culture at the concentration of 50 μg/ml with an antiviral index of 2.07 and 3.53, respectively.
Emodin treatment also increased the survival rate of HSV-infected mice, prolonged survival time and showed higher efficacy of HSV elimination from brain, heart, liver, and ganglion, compared to the controls.
In vivo, researchers found that emodin demonstrates the antiviral activity similar to that of acyclovir, an antiviral medication.
Compared to the efficacy of antiviral activity of nucleoside analogs against herpes simplex virus (HSV) infections, injection of emodin specifically inhibited the nuclease activity of HSV-1 UL12 alkaline nuclease, which is necessary for the production of viral DNA according to the biochemical assay.
Emodin reduced the plaque formation or cell to cell infection with an EC50 of 21.5±4.4 μm, according to the plaque reduction assay.
Emodin also inhibited the accumulation of viral nucleocapsids in the nucleus in the initiation of viral transcription and replication in a dose-dependent manner.
Dr. C-Y Hsiang and colleagues suggested that emodin is a potent anti-HSV agent via the suppression of a novel target, UL12.
Taken altogether, herbal Cascara Sagrada processed abundantly bioactive ingredient emodin may be considered a functioning remedy for the prevention and combined with primary medicine for the treatment of viral infection, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
References
(1) Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures by C-Y Hsiang1 and T-Y Ho. (PMC)
(2) The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo by Xiong HR1, Luo J, Hou W, Xiao H, Yang ZQ.(PubMed)
(3) Immune factor allows viral infections to become chronic. Study may lead the way to new therapeutic approaches by Science Daily
Similar to bacterial infection, both infections shared common characteristics by spreading through coughing and sneezing by and contact with infected people, especially through kissing and sex.
However, the virus may also cause infection by entering the body through wound and cut. Most viruses are killed in the acute phase of the infection.
During this phase, the immune system stimulates the constriction of blood vessels in speeding up the production of blood palette to cover the wound and production of inflammatory cytokines to the site of infection to fight off the bacterial and viral invasion.
The most common viruses that cause infection are hepatitis A, B, human papillomavirus (HPV) influenza. mumps, and rubella. People with a weakened immune system are susceptible to acute and chronic viral infections.
According to the article immune factor allows viral infections to become chronic by the University of Bonn, many viral diseases tend to become chronic, including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently".
Some researchers argued that the chronic infectious diseases may be a result of a weakened immune system which can not kill off the virus with the set period of time during the acute phase of infection, leading to the adaptation of the change, thus reducing the helper T cells in the secretion of inflammatory messengers and reduced function of the tumor necrosis factor in chronic infection compared to the acute phase of infection.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America.
The herbal bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.,
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
Researchers on finding a natural compound for the treatment of viral infection examined the effects of emodin, active ingredients from Rheum tanguticum (R. tanguticum, one of the Chinese Rhubarb) and Cascara Sagrada against HSV infection in tissue culture cells and in a mouse model.
Emodin displayed significant inhibition of the replication of HSV-1 and HSV-2 in cell culture at the concentration of 50 μg/ml with an antiviral index of 2.07 and 3.53, respectively.
Emodin treatment also increased the survival rate of HSV-infected mice, prolonged survival time and showed higher efficacy of HSV elimination from brain, heart, liver, and ganglion, compared to the controls.
In vivo, researchers found that emodin demonstrates the antiviral activity similar to that of acyclovir, an antiviral medication.
Compared to the efficacy of antiviral activity of nucleoside analogs against herpes simplex virus (HSV) infections, injection of emodin specifically inhibited the nuclease activity of HSV-1 UL12 alkaline nuclease, which is necessary for the production of viral DNA according to the biochemical assay.
Emodin reduced the plaque formation or cell to cell infection with an EC50 of 21.5±4.4 μm, according to the plaque reduction assay.
Emodin also inhibited the accumulation of viral nucleocapsids in the nucleus in the initiation of viral transcription and replication in a dose-dependent manner.
Dr. C-Y Hsiang and colleagues suggested that emodin is a potent anti-HSV agent via the suppression of a novel target, UL12.
Taken altogether, herbal Cascara Sagrada processed abundantly bioactive ingredient emodin may be considered a functioning remedy for the prevention and combined with primary medicine for the treatment of viral infection, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
References
(1) Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures by C-Y Hsiang1 and T-Y Ho. (PMC)
(2) The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo by Xiong HR1, Luo J, Hou W, Xiao H, Yang ZQ.(PubMed)
(3) Immune factor allows viral infections to become chronic. Study may lead the way to new therapeutic approaches by Science Daily
Friday, January 3, 2020
Herbal Calendula Which Processes Anti-Plaque and Gingivitis Activity, revealed by Human Studies
Scientists may have found a natural ingredient that has a potential effect against the onset of gingivitis, according to studies.
Gingivitis is a condition of the inflammation of the gum. The most common cause of the disease is poor hygiene in the induction of bacterial biofilms attached to tooth surfaces.
Gingivitis is an early stage of gum disease, leading to the inflammation in inducing plaque buildup at the gumline. Daily brushing and flossing in most cases can remove the plaque, without the assistance of the dentist.
However, if daily brushing and flossing can not remove the plaque, please check with your dentist.
Untreated gingivitis can weaken the bone and connective tissue that hold the teeth in place, causing to periodontitis and the loss of tooth or teeth.
Besides poor hygiene, smoking or chewing tobacco, medical conditions such as diabetes, long-term intake of certain medications such as oral contraceptives, steroids, anticonvulsants, a denture that fit poorly, broken fillings, pregnancy, and genetic deposition are some risk factors associated with the onset of gingivitis.
Dr. Nascimento GG, the lead scientist, in the concern of widespread obesity in the risk of gingivitis launched a study of a total of 1211 children aged 8- to 12-year old from the public and private schools in Southern Brazil by a two-stage cluster method.
In the oral examination, the presence of plaque and gingival bleeding were found in 34.6% in Obese/overweight children, compared to the mean and median values of gingival bleeding sites were 3.10 and 2.0 respectively in the group.
According to the In the sex-stratified analysis, researchers said, "overweight/obese boys presented a greater risk for gingivitis".
The discovery strongly suggested there is a closed link between gingivitis and people who are obese.
Calendula is also known as pot marigold, the annual perennial herbaceous plants of about 12–20 species of genus Calendula, belonging to the family Asteraceae, native to Southern Europe.
The herbal medicine has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and for the treatment of abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.
Besides major chemical constituents of triterpenoids, flavonoids, coumarines, quinones, volatile oil, carotenoids, and amino acids, the herb also contains loliolide (calendin), calendulin and n-
Researchers on finding natural ingredients for the prevention and treatment of with no side effects examined the herbal Calendula officinalis anti-plaque and anti-gingivitis activity.
240 patients having gingivitis (probing depth (PD) ≤3 mm), with a complaint of bleeding gums within the age group of 20-40 years enrolled with their informed consent were included in this study.
The subjects were randomly assigned into two groups - test group (n = 120) and control group (n = 120).
All the test group patients were advised to dilute 2 ml of tincture of calendula with 6 ml of distilled water and rinse their mouths once in the morning and once in the evening for six months. Similarly, the control group patients were advised to use 8 ml distilled water (placebo) as a control mouthwash and rinse mouth twice daily for six months.
In the absence of scaling (that is, between the first and second visit), the test group showed a statistically significant reduction in the scores of plaque index (PI), gingival index (GI), sulcus bleeding index (SBI), and oral hygiene index-simplified (OHI-S) compared to the control group when the baseline scores were compared with the third-month scores.
However, when scaling was performed during the third month (second visit), there was a statistically significant reduction in the scores of all parameters when the third-month scores were compared with the sixth-month scores in both groups, but the test group showed a significantly greater reduction in the PI, GI, SBI, and OHI-S scores compared to that of the control group.
These results clearly suggested that calendula mouthwash is effective in reducing dental plaque and gingivitis adjunctive to scaling, according to the researchers.
In order to reveal more information about herbal Calendula anti-gingivitis effects, researchers investigated the effects of a topic gel containing clobetasol propionate and Calendula officinalis L in an acetate tray over two years.
The study included 2 patients with a diagnosis of lichen planus presenting as DG, researchers found that the symptomatic outbreaks were delayed and presented as less severe symptoms in the two years follow-up.
The findings indicated the topic of gel treatment reduces the length and severity of symptomatic outbreaks desquamative gingivitis.
Taken altogether, herbal Calendula may be used as a mouthwash or topical gel for the prevention and treatment of gingivitis with no side effects, pending the result of a larger and multicenter human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent by Khairnar MS, Pawar B, Marawar PP, Mani A.(PubMed)
(2) Management of two cases of desquamative gingivitis with clobetasol and Calendula officinalis gel by Machado MA1, Contar CM, Brustolim JA, Candido L, Azevedo-Alanis LR, Gregio AM, Trevilatto PC, Soares de Lima AA. (PubMed)
(3) Are obesity and overweight associated with gingivitis occurrence in Brazilian schoolchildren by Nascimento GG1, Seerig LM, Vargas-Ferreira F, Correa FO, Leite FR, Demarco FF. (PubMed)
Gingivitis is a condition of the inflammation of the gum. The most common cause of the disease is poor hygiene in the induction of bacterial biofilms attached to tooth surfaces.
Gingivitis is an early stage of gum disease, leading to the inflammation in inducing plaque buildup at the gumline. Daily brushing and flossing in most cases can remove the plaque, without the assistance of the dentist.
However, if daily brushing and flossing can not remove the plaque, please check with your dentist.
Untreated gingivitis can weaken the bone and connective tissue that hold the teeth in place, causing to periodontitis and the loss of tooth or teeth.
Besides poor hygiene, smoking or chewing tobacco, medical conditions such as diabetes, long-term intake of certain medications such as oral contraceptives, steroids, anticonvulsants, a denture that fit poorly, broken fillings, pregnancy, and genetic deposition are some risk factors associated with the onset of gingivitis.
Dr. Nascimento GG, the lead scientist, in the concern of widespread obesity in the risk of gingivitis launched a study of a total of 1211 children aged 8- to 12-year old from the public and private schools in Southern Brazil by a two-stage cluster method.
In the oral examination, the presence of plaque and gingival bleeding were found in 34.6% in Obese/overweight children, compared to the mean and median values of gingival bleeding sites were 3.10 and 2.0 respectively in the group.
According to the In the sex-stratified analysis, researchers said, "overweight/obese boys presented a greater risk for gingivitis".
The discovery strongly suggested there is a closed link between gingivitis and people who are obese.
Calendula is also known as pot marigold, the annual perennial herbaceous plants of about 12–20 species of genus Calendula, belonging to the family Asteraceae, native to Southern Europe.
The herbal medicine has been used in herbal medicine as spasmolytic, spasmogenic, inflammatory effects and for the treatment of abdominal cramps, wound healing, skin diseases, colitis, constipation, etc.
Besides major chemical constituents of triterpenoids, flavonoids, coumarines, quinones, volatile oil, carotenoids, and amino acids, the herb also contains loliolide (calendin), calendulin and n-
Researchers on finding natural ingredients for the prevention and treatment of with no side effects examined the herbal Calendula officinalis anti-plaque and anti-gingivitis activity.
240 patients having gingivitis (probing depth (PD) ≤3 mm), with a complaint of bleeding gums within the age group of 20-40 years enrolled with their informed consent were included in this study.
The subjects were randomly assigned into two groups - test group (n = 120) and control group (n = 120).
All the test group patients were advised to dilute 2 ml of tincture of calendula with 6 ml of distilled water and rinse their mouths once in the morning and once in the evening for six months. Similarly, the control group patients were advised to use 8 ml distilled water (placebo) as a control mouthwash and rinse mouth twice daily for six months.
In the absence of scaling (that is, between the first and second visit), the test group showed a statistically significant reduction in the scores of plaque index (PI), gingival index (GI), sulcus bleeding index (SBI), and oral hygiene index-simplified (OHI-S) compared to the control group when the baseline scores were compared with the third-month scores.
However, when scaling was performed during the third month (second visit), there was a statistically significant reduction in the scores of all parameters when the third-month scores were compared with the sixth-month scores in both groups, but the test group showed a significantly greater reduction in the PI, GI, SBI, and OHI-S scores compared to that of the control group.
These results clearly suggested that calendula mouthwash is effective in reducing dental plaque and gingivitis adjunctive to scaling, according to the researchers.
In order to reveal more information about herbal Calendula anti-gingivitis effects, researchers investigated the effects of a topic gel containing clobetasol propionate and Calendula officinalis L in an acetate tray over two years.
The study included 2 patients with a diagnosis of lichen planus presenting as DG, researchers found that the symptomatic outbreaks were delayed and presented as less severe symptoms in the two years follow-up.
The findings indicated the topic of gel treatment reduces the length and severity of symptomatic outbreaks desquamative gingivitis.
Taken altogether, herbal Calendula may be used as a mouthwash or topical gel for the prevention and treatment of gingivitis with no side effects, pending the result of a larger and multicenter human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent by Khairnar MS, Pawar B, Marawar PP, Mani A.(PubMed)
(2) Management of two cases of desquamative gingivitis with clobetasol and Calendula officinalis gel by Machado MA1, Contar CM, Brustolim JA, Candido L, Azevedo-Alanis LR, Gregio AM, Trevilatto PC, Soares de Lima AA. (PubMed)
(3) Are obesity and overweight associated with gingivitis occurrence in Brazilian schoolchildren by Nascimento GG1, Seerig LM, Vargas-Ferreira F, Correa FO, Leite FR, Demarco FF. (PubMed)
Herbal Ashwagandha the Anti Rheumatoid Arthritis Herbal Medicine
Rheumatoid Arthritis, a type of musculoskeletal disorders (MSDs) is a chronic disorder characterized by inflammation of the flexible (synovial) joints and tissues and organs in the body.
The disease affects more women than men and generally occurs after the ages of 50, causing the diminished quality of life of many elders.
Musculoskeletal disorders (MSDs) are medical conditions mostly caused by work-related occupations and working environments, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time.
According to a community sample of 73 females and 32 males aged 85 and over who underwent a standardized examination at home, musculoskeletal pain was reported by 57% of those interviewed.
According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affects over 52 million adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.
Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.
A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.
Patient with rheumatoid arthritis (RA) often associates to valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot. The kinematic and kinetic gait changes in rheumatoid arthritis (RA) are the result of a significant reduction in joint motions, joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...
Long-term bone damage and the prolonged onset of the disease can induce deformities of hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.
The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations physically that can affect daily living and quality of life.
Furthermore, rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with RA.
Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in the early stage of rheumatoid arthritis.
Dr. Motl RW and Dr. McAuley E. in the assessment of chronic diseases said, " The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) are embedded in the "Graying of America""(29), including patients with RA.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of arthritis, researchers examined the effect of Cannabis sativa, Prunella vulgaris, and Withania somnifera) possess anti-inflammatory, and-rheumatic arthritis properties.
According to the tested analysis, the tested medical plants showed a significant effect on RA by targeting TNF-α through its anti-inflammatory activity.
More precisely, twenty unique molecules found in the medical plants including Withania somnifera were attributed to the utmost binding affinity, least binding energies associated with the interaction of receptor-ligand interactions of residues against RA.
Based on the findings, researchers said, " the RA patients should use reported compounds for the prescription of RA by targeting TNF-α. This report is opening new dimensions for designing innovative therapeutic targets to cure RA.".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of RA, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withaniasomnifera compounds elucidating the medicinal properties against rheumatoid arthritis by Zaka M1, Sehgal SA2, Shafique S3, Abbasi BH. (PubMed)
(2) Most Common Diseases of elder: The Clinical Trials and Studies of musculoskeletal disorders: Osteoporosis - The Symptoms by Kyle J. Norton
(3) Physical activity, disability, and quality of life in older adults by Motl RW1, McAuley E. (PubMed)
The disease affects more women than men and generally occurs after the ages of 50, causing the diminished quality of life of many elders.
Musculoskeletal disorders (MSDs) are medical conditions mostly caused by work-related occupations and working environments, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time.
According to a community sample of 73 females and 32 males aged 85 and over who underwent a standardized examination at home, musculoskeletal pain was reported by 57% of those interviewed.
According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affects over 52 million adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.
Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.
A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.
Patient with rheumatoid arthritis (RA) often associates to valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot. The kinematic and kinetic gait changes in rheumatoid arthritis (RA) are the result of a significant reduction in joint motions, joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...
Long-term bone damage and the prolonged onset of the disease can induce deformities of hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.
The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations physically that can affect daily living and quality of life.
Furthermore, rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with RA.
Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in the early stage of rheumatoid arthritis.
Dr. Motl RW and Dr. McAuley E. in the assessment of chronic diseases said, " The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) are embedded in the "Graying of America""(29), including patients with RA.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of arthritis, researchers examined the effect of Cannabis sativa, Prunella vulgaris, and Withania somnifera) possess anti-inflammatory, and-rheumatic arthritis properties.
According to the tested analysis, the tested medical plants showed a significant effect on RA by targeting TNF-α through its anti-inflammatory activity.
More precisely, twenty unique molecules found in the medical plants including Withania somnifera were attributed to the utmost binding affinity, least binding energies associated with the interaction of receptor-ligand interactions of residues against RA.
Based on the findings, researchers said, " the RA patients should use reported compounds for the prescription of RA by targeting TNF-α. This report is opening new dimensions for designing innovative therapeutic targets to cure RA.".
Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of RA, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withaniasomnifera compounds elucidating the medicinal properties against rheumatoid arthritis by Zaka M1, Sehgal SA2, Shafique S3, Abbasi BH. (PubMed)
(2) Most Common Diseases of elder: The Clinical Trials and Studies of musculoskeletal disorders: Osteoporosis - The Symptoms by Kyle J. Norton
(3) Physical activity, disability, and quality of life in older adults by Motl RW1, McAuley E. (PubMed)
Cat's Claw, the Best Whole Herb medicine for Treatment of Type I Diabetes
Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Progression of immune-mediated diabetes or Type 1 diabetes mellitus is a chronic T cell-mediated disease resulting from autoimmune destruction of pancreatic beta-cells.
A recent study suggested that Cat's Claw may be effective for the treatment of diabetes-induced by Th1/Th2 (T cell) cytokine production.
In vivo, immunotoxicity testing, BALB/c male mice treated once a day with 125, 500 or 1250 mg/kg of U. tomentosa extract for 28 days, increased the number of T helper lymphocytes and B lymphocytes. The whole herb medicine also significantly exerted a large stimulatory effect on lymphocyte(a form of small white blood cell) viability.
Other study involved C57BL/6 male mice injected with MLDS (40 mg/kg) orally treated with UT at 10-400mg/kg during 21 days, showed to express a significant protection against the loss of insulin-secreting presented β-cells, through modulated the production of two helper T cell classes, known as Th1 and Th2, with increased levels of type-2 T helper cells and mast cells, known as IL-5 and the protein regulated activities of white blood cells known as IL-2.
Further linking Interleukin-2 effected on type I diabetes, the study of Interleukin-2 and type 1 diabetes and several autoimmune diseases suggested that depended on interleukin-2 (IL-2) in proliferating and controlling the T effector cells (Teff) reaction, low dose IL-2 treatment at the initial time of diabetes can rescue insulin secretion by restoring proteins expression.
Dr. Rosenzwajg M, the lead author said, " Regulatory T cells (Tregs) play a major role in controlling effector T cells (Teffs) responding to self-antigens, which cause autoimmune diseases.,....and expanding/activating Tregs with low-dose interleukin-2 (IL-2) could provide immunoregulation without immunosuppression"
Cat's Claw may be effective in protein regulated activities of white blood cells, known as IL-2 through the improvement of immune function in induced immunosuppression cause of Type I diabetes, but the quantity intake should only be prescribed by professional herbalist to prevent toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory T cell preservation or both? by Domingues A1, Sartori A, Golim MA, Valente LM, da Rosa LC, Ishikawa LL, Siani AC, Viero RM.(PubMed)
(2) Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile by Domingues A1, Sartori A, Valente LM, Golim MA, Siani AC, Viero RM.(PubMed)
(3) Interleukin-2 and type 1 diabetes: new therapeutic perspectives by Hartemann A1, Bourron O.(PubMed)
(4) Interleukin 2 in the pathogenesis and therapy of type 1 diabetes by Rosenzwajg M1, Churlaud G, Hartemann A, Klatzmann D.(PubMed)
Thursday, January 2, 2020
Herbal Cascara Sagrada (Rhamnus purshiana)The Natural Laxative for Acute and Chronic Constipation with No Side Effects, Scientists Discover
Herbal Cascara Sagrada may have a potential and positive effect in reducing risks and treatment of constipation, according to studies.
Constipation is a condition of infrequent bowel movements caused by hard and dry stool.
Without bowel movement that lasts longer than 3 days is considered having a condition of constipation
Chronic constipation can lead to symptoms of abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement.
In severe cases, chronic constipation can cause the complications of formation of hemorrhoids, anal fissure or fecal impaction.
According to the statistic, constipation most often affects women, adults ages 65 and older. Constipation is highly prevalent, with approximately 12 million general practitioner prescriptions for laxatives in England in 2001.
Most common risk factors for the onset of the condition including, a poor diet with less fiber, overuse of laxatives, certain medical conditions such as irritable bowel syndrome, colon cancer, long-term use of certain medications, such as narcotics, antidepressants and resisting the urge to poop.
Some researchers suggested that atypical defecation habits are one of the most risk factors associated with the risk of constipation that is harder to treat.
Ms. Isabelle Beaudry-Bellefeuille in the examine the risk chronic constipation with atypical defecation habits in children, wrote, "Atypical defecation habits are common and distressing for children and families and can have a major impact on the quality of life. Often, no underlying factor can be identified, and the defecation disorder is considered functional".
And, "Current interventions are not successful for up to 50% of children. We suggest this high failure rate may be caused by a lack of consistency in the descriptors of behavioral indicators for functional defecation problems. Most investigations and descriptors focus on general behavior. There are fewer reports concerning defecation-specific behaviors".
More investigations are necessary before a strategy can be found for the treatment of chronic constipation with atypical defecation habits in children.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America. The herbal bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
Researchers in the concerns of the high prevalence of constipation used of laxatives, a colon addictive substance, examined the effects of cascara sagrada accompanied by the infection of ear mushrooms.
A total of 34 patients diagnosed with functional constipation according to the definition of the modified Rome II criteria. divided into 3 groups (placebo, ear mushrooms alone, and ear mushrooms with additives including cascara sagrada, etc.).
Numbers of bowel movement, straining, sense of incomplete evacuation, stool consistency, satisfactory relief, abdominal pain/discomfort and colon transit time were evaluated and analyzed before, during and after the treatment.
Both ear mushrooms alone and ear mushrooms with additives significantly improved a number of bowel movements, straining, sense of incomplete evacuation.
Furthermore, both applications also improved stool consistency and satisfactory relief in the participants.
Compared to the use of ear mushrooms alone, adding herbal Cascara Sagrada was found to be more effective in the improvement of constipation.
However, compared to no side effects on the use of ear mushrooms, adding herbal Cascara Sagrada may induce mild gastrointestinal discomforts in some patients.
The results clearly suggested that ear mushrooms combined with herbal Cascara Sagrada and fiber may have a strong inhibition against the development and chronic constipation with no serious effects.
Taken altogether, herbal Cascara Sagrada may be used alone or combined with other anti-constipation functional foods for the prevention and treatment of chronic constipation with little or no side effects.
However, due to the limitation of the small sample size, we suggested that the confirmation by a large sample and multicenter human study is necessary before declaring the effective use of herbal Cascara Sagrada and its combination for the treatment of constipation.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Rhamnus purshiana (Cascara)
(2) Constipation in adults. by Mueller-Lissner SA, Wald A.(PubMed)
(3) [Effect of ear mushroom (Auricularia) on functional constipation].[Article in Korean] by Kim TI, Park SJ, Choi CH, Lee SK, Kim WH.(PubMed)
(4) Defecation-Specific Behavior in Children with Functional Defecation Issues: A Systematic Review by Isabelle Beaudry-Bellefeuille, MSc. (PMC)
Constipation is a condition of infrequent bowel movements caused by hard and dry stool.
Without bowel movement that lasts longer than 3 days is considered having a condition of constipation
Chronic constipation can lead to symptoms of abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement.
In severe cases, chronic constipation can cause the complications of formation of hemorrhoids, anal fissure or fecal impaction.
According to the statistic, constipation most often affects women, adults ages 65 and older. Constipation is highly prevalent, with approximately 12 million general practitioner prescriptions for laxatives in England in 2001.
Most common risk factors for the onset of the condition including, a poor diet with less fiber, overuse of laxatives, certain medical conditions such as irritable bowel syndrome, colon cancer, long-term use of certain medications, such as narcotics, antidepressants and resisting the urge to poop.
Some researchers suggested that atypical defecation habits are one of the most risk factors associated with the risk of constipation that is harder to treat.
Ms. Isabelle Beaudry-Bellefeuille in the examine the risk chronic constipation with atypical defecation habits in children, wrote, "Atypical defecation habits are common and distressing for children and families and can have a major impact on the quality of life. Often, no underlying factor can be identified, and the defecation disorder is considered functional".
And, "Current interventions are not successful for up to 50% of children. We suggest this high failure rate may be caused by a lack of consistency in the descriptors of behavioral indicators for functional defecation problems. Most investigations and descriptors focus on general behavior. There are fewer reports concerning defecation-specific behaviors".
More investigations are necessary before a strategy can be found for the treatment of chronic constipation with atypical defecation habits in children.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America. The herbal bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
Researchers in the concerns of the high prevalence of constipation used of laxatives, a colon addictive substance, examined the effects of cascara sagrada accompanied by the infection of ear mushrooms.
A total of 34 patients diagnosed with functional constipation according to the definition of the modified Rome II criteria. divided into 3 groups (placebo, ear mushrooms alone, and ear mushrooms with additives including cascara sagrada, etc.).
Numbers of bowel movement, straining, sense of incomplete evacuation, stool consistency, satisfactory relief, abdominal pain/discomfort and colon transit time were evaluated and analyzed before, during and after the treatment.
Both ear mushrooms alone and ear mushrooms with additives significantly improved a number of bowel movements, straining, sense of incomplete evacuation.
Furthermore, both applications also improved stool consistency and satisfactory relief in the participants.
Compared to the use of ear mushrooms alone, adding herbal Cascara Sagrada was found to be more effective in the improvement of constipation.
However, compared to no side effects on the use of ear mushrooms, adding herbal Cascara Sagrada may induce mild gastrointestinal discomforts in some patients.
The results clearly suggested that ear mushrooms combined with herbal Cascara Sagrada and fiber may have a strong inhibition against the development and chronic constipation with no serious effects.
Taken altogether, herbal Cascara Sagrada may be used alone or combined with other anti-constipation functional foods for the prevention and treatment of chronic constipation with little or no side effects.
However, due to the limitation of the small sample size, we suggested that the confirmation by a large sample and multicenter human study is necessary before declaring the effective use of herbal Cascara Sagrada and its combination for the treatment of constipation.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Rhamnus purshiana (Cascara)
(2) Constipation in adults. by Mueller-Lissner SA, Wald A.(PubMed)
(3) [Effect of ear mushroom (Auricularia) on functional constipation].[Article in Korean] by Kim TI, Park SJ, Choi CH, Lee SK, Kim WH.(PubMed)
(4) Defecation-Specific Behavior in Children with Functional Defecation Issues: A Systematic Review by Isabelle Beaudry-Bellefeuille, MSc. (PMC)
Herbal Artichoke Protects Us Against Liver Disease
The liver is the largest organ in the human body besides processing the function in filtering blood from the digestive system before passing them to other parts of the body, it also detoxifies toxic chemicals and metabolizes drugs and secretes bile to assist the digestive function in breaking down food.
Liver protective activity is an action that protects the liver functioning by blocking any substance or pathogens that can cause liver injury or damage.
The exact causes of liver disease are not identified. Researchers do not know why a person is prone to the disease onset while other person does not, even they share a similar health condition and family history
According to the medical literature, there is a perception that liver disease mostly caused by excessive alcohol drinking and viral infection. However, as the time progression, many studies also found that obesity, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome also play a critical role in developing liver disease.
Some researchers suggested that people with the weakened immune system or immune deficiency are also at an increased risk of liver disease.
Dr. Hadzic N. in the investigation of immune deficiency related liver disease wrote, "It is estimated that around one-quarter of patients with a primary immune deficiency will have some degree of liver involvement".
And, "The most common primary immune deficiencies associated with the liver disease are combined immune deficiency (CID), hyper-IgM syndrome, common variable immunodeficiency, while the commonest liver disease being sclerosing cholangitis"
Most common symptoms of liver disease are jaundice, itchy skin Skin, dark urine color, and pale stool color.
Some patient may also experience symptoms of abdominal pain and swelling, swelling in the legs and ankles and persistent fatigue.
Therefore, if you have some of the aforementioned symptoms, please check with your doctor to rule the possibility.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Searching the list of natural compounds with liver protective activity, researchers examined the effects of artichoke in liver dysfunctions.
The study included the preparation of 4 extract concentrations (0.62, 1.25, 2.5 and 5.0 mg/mL) evaluated on human hepatocyte cultures, HepG2 cells, using the comet assay.
Injection of extract concentrations of 0.62, 1.25 and 2.5 mg/mL, exhibited a significant cytotoxic effect in pretreatment, compared to hydrogen peroxide alone.
However, in simultaneous and post-treatment protocols, only the lowest concentration of artichoke inhibited the frequency of DNA damage caused by hydrogen peroxide.
At highest concentration at 2.5 mg/mL, artichoke extract increased hydrogen peroxide genotoxicity against HepG2 cells.
These results suggested that artichoke leaves aqueous extract induced genotoxic effects in a concentration higher than .62 mg/mL in the tested cell line.
In other words, artichoke extract protects the liver against overexpression of free radicals in the initiation of liver cell damage in a dose-dependent manner.
Dr. da Silva RP, the lead scientist said, "artichoke is genotoxic, in vitro, to HepG2 cells, but can also modulate hydrogen peroxide DNA damage".
In order to reveal more information about artichoke liver protective effects, researchers examined the herbal effects in experimental animals hepatoxicity.
The study included rats divided into five groups: negative control, paracetamol (2 g/kg, single oral dose), ALE (1.5 g/kg, orally for 14 d), ALE + paracetamol, and NAC (100 mg/kg) + paracetamol.
The paracetamol treatment group showed marked liver damage observed by significantly increased activities of serum aminotransferases, particularly in the significant increase in hepatic MDA and NO levels, compared with the negative control group.
Paracetamol injection also decreased significantly the levels of antioxidant enzymes produced by the host such as GSH content, GR, GST, and SOD activities.
Furthermore, Paracetamol also induced liver cell apoptosis through its toxicity.
Pretreatment of ALE reversed all the parameters changed above including replenished hepatic GSH, reversed oxidative stress parameters, DNA damage, and necrosis.
Dr. El Morsy EM and colleague wrote in the final report, "ALE may protect from paracetamol-induced liver toxicity via its antioxidant and anti-apoptotic properties".
Taken altogether, artichoke may be considered a functional remedy for the protection of liver against toxicity, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Genotoxic and chemopreventive assessment of Cynara scolymus L. aqueous extract in a human-derived liver cell line by da Silva RP1, Jacociunas LV2, de Carli RF1, de Abreu BRR1, Lehmann M1, da Silva J3, Ferraz ABF4, Dihl RR. (PubMed)
(2) Protective effect of artichoke leaf extract against paracetamol-induced hepatotoxicity in rats by El Morsy EM1, Kamel R. (PubMed)
(3) Immune Deficiency-Related Liver Disease by Hadzic N. (Karger)
Liver protective activity is an action that protects the liver functioning by blocking any substance or pathogens that can cause liver injury or damage.
The exact causes of liver disease are not identified. Researchers do not know why a person is prone to the disease onset while other person does not, even they share a similar health condition and family history
According to the medical literature, there is a perception that liver disease mostly caused by excessive alcohol drinking and viral infection. However, as the time progression, many studies also found that obesity, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome also play a critical role in developing liver disease.
Some researchers suggested that people with the weakened immune system or immune deficiency are also at an increased risk of liver disease.
Dr. Hadzic N. in the investigation of immune deficiency related liver disease wrote, "It is estimated that around one-quarter of patients with a primary immune deficiency will have some degree of liver involvement".
And, "The most common primary immune deficiencies associated with the liver disease are combined immune deficiency (CID), hyper-IgM syndrome, common variable immunodeficiency, while the commonest liver disease being sclerosing cholangitis"
Most common symptoms of liver disease are jaundice, itchy skin Skin, dark urine color, and pale stool color.
Some patient may also experience symptoms of abdominal pain and swelling, swelling in the legs and ankles and persistent fatigue.
Therefore, if you have some of the aforementioned symptoms, please check with your doctor to rule the possibility.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Searching the list of natural compounds with liver protective activity, researchers examined the effects of artichoke in liver dysfunctions.
The study included the preparation of 4 extract concentrations (0.62, 1.25, 2.5 and 5.0 mg/mL) evaluated on human hepatocyte cultures, HepG2 cells, using the comet assay.
Injection of extract concentrations of 0.62, 1.25 and 2.5 mg/mL, exhibited a significant cytotoxic effect in pretreatment, compared to hydrogen peroxide alone.
However, in simultaneous and post-treatment protocols, only the lowest concentration of artichoke inhibited the frequency of DNA damage caused by hydrogen peroxide.
At highest concentration at 2.5 mg/mL, artichoke extract increased hydrogen peroxide genotoxicity against HepG2 cells.
These results suggested that artichoke leaves aqueous extract induced genotoxic effects in a concentration higher than .62 mg/mL in the tested cell line.
In other words, artichoke extract protects the liver against overexpression of free radicals in the initiation of liver cell damage in a dose-dependent manner.
Dr. da Silva RP, the lead scientist said, "artichoke is genotoxic, in vitro, to HepG2 cells, but can also modulate hydrogen peroxide DNA damage".
In order to reveal more information about artichoke liver protective effects, researchers examined the herbal effects in experimental animals hepatoxicity.
The study included rats divided into five groups: negative control, paracetamol (2 g/kg, single oral dose), ALE (1.5 g/kg, orally for 14 d), ALE + paracetamol, and NAC (100 mg/kg) + paracetamol.
The paracetamol treatment group showed marked liver damage observed by significantly increased activities of serum aminotransferases, particularly in the significant increase in hepatic MDA and NO levels, compared with the negative control group.
Paracetamol injection also decreased significantly the levels of antioxidant enzymes produced by the host such as GSH content, GR, GST, and SOD activities.
Furthermore, Paracetamol also induced liver cell apoptosis through its toxicity.
Pretreatment of ALE reversed all the parameters changed above including replenished hepatic GSH, reversed oxidative stress parameters, DNA damage, and necrosis.
Dr. El Morsy EM and colleague wrote in the final report, "ALE may protect from paracetamol-induced liver toxicity via its antioxidant and anti-apoptotic properties".
Taken altogether, artichoke may be considered a functional remedy for the protection of liver against toxicity, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Genotoxic and chemopreventive assessment of Cynara scolymus L. aqueous extract in a human-derived liver cell line by da Silva RP1, Jacociunas LV2, de Carli RF1, de Abreu BRR1, Lehmann M1, da Silva J3, Ferraz ABF4, Dihl RR. (PubMed)
(2) Protective effect of artichoke leaf extract against paracetamol-induced hepatotoxicity in rats by El Morsy EM1, Kamel R. (PubMed)
(3) Immune Deficiency-Related Liver Disease by Hadzic N. (Karger)
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