Herbal Burdock, the Natural Antibiotic Alternative

Scientists may have found a herbal plant for the prevention and treatment of bacterial infection with no side effects, according to studies.

Infection is a result of the invasion of microorganisms that have successfully multiplied in the host body and the reaction of host tissues.

Bacteria is a single cell microorganism. Most bacterias are not harmful, some may also benefit the digestive system. However, 1% of invasive bacteria can make us sick and damage the body tissue, such as bacteria associated with tuberculosis.

There are many ways to cause infection including bacteria passed from person to person, transmitted by bites from insects or animals. and ingesting contaminated food or water.

The most common symptoms of infectious diseases are fever, diarrhea, fatigue, muscle aches, coughing, depending on the specific area of infection.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases.


Most bacteria are killed in the first phase of acute infection. In this phase, the immune white blood cells in the first line of defense in responding to the body tissue damage or injury by stimulating the production of proinflammatory cytokines to kill off all invasive pathogens on the site of damage.


However, overexpression of proinflammatory cytokines in most cases can destroy the nearby healthy cells, leading to the formation of scars as seen in liver infection.

What contributes to the overexpression proinflammatory and underexpression of anti-inflammatory cytokines of the body in the initiation of chronic inflammatory diseases?

Dr. Thomas W. McDade and colleagues in the investigation of the role of proinflammatory cytokines in the risk of infection explained, "the metabolic syndrome may be characterized by dysregulated inflammation, in which an important anti-inflammatory signal is absent. Similarly, in a prospective study of patients with acute coronary syndromes, baseline IL-10 concentration was a significant predictor of death or myocardial infarction during 6 months of follow up, ......high IL-10 experienced an adverse outcome, compared to 21.8% of patients with high CRP but low IL-10


Burdock is a plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro.

The plant has been used thousands of years in China medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.

With an aim to the discovery of natural bio components from plants with antibacterial activity on endodontic microbiota for the new therapies, researchers evaluated the antibacterial activity of a phytotherapeutic agent prepared from an ethyl acetate fraction (AcOEt) extracted from Arctium lappa.

A total of 27 maxillary canines with a mixed bacterial suspension of Pseudomonas aeruginosa, Escherichia coli, Lactobacillus acidophilus, Streptococcus mutans a Candida albicans were included in the study.

The teeth were divided into three groups and their canals filled with: group 1, calcium hydroxide and propylene glycol; group 2, a paste containing AcOEt fraction of A. lappa (Burdock) and propylene glycol; group 3, propylene glycol (control).

At 7, 14 and 30 days, three teeth from each group opened, researchers found that mild bacterial growth was found in group 1 at all time intervals; in group 2 there was severe growth at 7 days, but no growth at 14 and 30 days.


These results indicated a significant antibacterial effect of AcOEt fraction of A. lappa in inhibiting the growth of all the microorganisms.

Furthermore, in vitro, the antimicrobial activity of rough extracts from leaves of Arctium lappa showed inhibition of Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, and Candida albicans selectively to specific target microorganisms.

In other words, each constituent in the extract of Burdock inhibited only a certain type of endodontic pathogens without affecting others.


Dr.Pereira JV, the lead author said, "the Arctium lappa constituents exhibited a great microbial inhibition potential against the tested endodontic pathogens".

More importantly, in the review of the antimicrobial activity against bacteria and yeasts of extracts of 13 Brazilian medicinal plants, researchers found that only 10 plant extracts showed varied levels of antibacterial activity.

Arctium lappa exerted some degree of antibacterial activity compared to other plants, including Mikania glomerata, Sambucus canadensis, Plantago major and Erythrina species.

Burdock was one of 5 plants belonging to the Asteraceae family that demonstrated the Rf values similar to the antibacterial compounds visible on bioautogram.

The finding strongly suggested Burdock and other 4 plants in the Asteraceae family may be used for the treatment of various infectious diseases.

Taken altogether, herbal Burdock may be considered a functional herb for the prevention and combined with other primary medicine for the treatment of infectious diseases.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) In vitro evaluation of the antibacterial activity of Arctium lappa as a phytotherapeutic agent used in intracanal dressings by Gentil M, Pereira JV, Sousa YT, Pietro R, Neto MD, Vansan LP, de Castro França S.(PubMed)
(2) Antimicrobial activity of Arctium lappa constituents against microorganisms commonly found in endodontic infections by Pereira JV, Bergamo DC, Pereira JO, França Sde C, Pietro RC, Silva-Sousa YT.(PubMed)
(3) Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases by Holetz FB, Pessini GL, Sanches NR, Cortez DA, Nakamura CV, Filho BP. (PubMed)
(4) Comparative insights into the regulation of inflammation: Levels and predictors of interleukin 6 and interleukin 10 in young adults in the Philippines by Thomas W. McDade,1,2 Paula S. Tallman,1 Linda S. Adair,3 Borja Judith,4 and Christopher W. Kuzawa. (PMC)

Herbal Ashwagandha Gobbles Up Human Head and Neck Cancer Cells In Vitro

Cancer is a group of diseases associated with cell growth disorderly and uncontrollably in the tissue of a specific organ. Over time cancer can become progressively worse and damage other healthy tissues.

Most cases of cancer start in the cells on the surface in the inner lining tissue of a specific organ, before traveling a distance away to affect other nearby tissue and organ.

Head and neck cancer is a class of cancer including the mouth, nose, throat, larynx, sinuses, or salivary glands.

Most cases of head and neck cancer start in the cell of the inner lining of the affected tissue. Patients with head and neck cancer at the very early stage are asymptomatic due to the very small size of the tumor.

However, at the later stage, the cancer cell can travel a distance away from the original site to infect other healthy tissues and organs, leading to secondary metastasis.

The exact causes of head and neck cancer are not identified. However, researchers found that excessive alcohol intake, smoking, infected by the HPV virus, poor oral health, race, long-term exposure to wood dust are prevalent factors associated with an increased risk of head and neck cancer.

Dr. Kazuhiro Kobayashi in the investigation of the risk of HPV on head and neck cancer (HNC) wrote, " Infection with high-risk human papillomaviruses (HPVs) has recently been implicated in the pathogenesis of HNSCCs. It is now widely accepted that high-risk HPV is a cause of almost all cervical cancers as well as some forms of HNSCCs. HPV-related HNSCCs are increasing".

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of cancers, researchers examined the apoptotic activity of methanol extract of Ashwagandha (MEAG) and in human head and neck squamous cell carcinoma (HNSCC) cells.

In vitro, in human head and neck squamous cell carcinoma (HNSCC) cells treated by MEAG showed dose-dependent growth-inhibitory activity involved in caspase-dependent apoptosis.

The inhibition of human head and neck squamous cell carcinoma (HNSCC) was attributed to induce the loss of mitochondrial membrane, the release of cytochrome c, accompanied by the activation of caspase 9 the apoptotic pathway.


Furthermore, Bim, truncated Bid (t-Bid), cleaved caspase-8, and death receptor 5 (DR5), associated with pro-apoptotic activity was also a significant increase upon the injection of MEAG.

Moreover, the major constituent withaferin A (WA), a bioactive component of MEAG.also expressed similar effects to those of MEAG.

Based on the findings, researchers said, " MEAG and WA may be potential natural materials for the treatment of HNSCC.".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of head and neck squamous cell carcinoma (HNSCC), pending to the result of larger sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anticancer activity of Ashwagandha against human head and neck cancer cell lines by Lee HE1, Shin JA1, Jeong JH2, Jeon JG3, Lee MH4, Cho SD. (PubMed)
(2) Withaferin A induces apoptosis through the generation of thiol oxidation in human head and neck cancer cells by Park JW1, Min KJ2, Kim DE1, Kwon TK. (PubMed)
(3) A Review of HPV-Related Head and Neck Cancer by Kazuhiro Kobayashi,1 Kenji Hisamatsu,1 Natsuko Suzui,1 Akira Hara,1,2 Hiroyuki Tomita,2,* andTatsuhiko Miyazaki. (PMC)

Herbal Bilberry, the Natural Treatment of Chronic Pruritus

Pruritus is a severe itching of the skin, as a symptom of various ailments. It is a frequent complaint heard by dermatologists and primary care physicians.

According to the statistics provided by Dr. Elke Weisshaar and Dr. Uwe Matterne, in children, pruritus is a cardinal symptom of atopic eczema (atopic dermatitis)associated with the prevalent risk between 6.1% and 22.3% in the Western countries.

There are many causes associated with the itching skin including aging that worsened dry skin condition, dry skin, eczema, psoriasis, scabies, burns, scars, insect bites, and hives.and diseases associated with the liver and kidney

Most symptoms of pruritus are due to scratching, including skin redness, bumps, crack, and scaly skin, depending on the causes of the symptoms.

For some instances, an allergic reaction can induce pruritus involved in touching clothing, pets, chemicals, soaps, and cosmetics and foods caused by an overreaction of the immune system in the production of cytokines against allergens.

Some researchers suggested that some people may experience an itching feeling with no physical cause. And patients with depression anxiety obsessive-compulsive disorder have been found to have an urge to scratch.

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

On finding a potential compound for the treatment of pruritus, researchers at the Chiba Univ examined the bilberry anthocyanins' antipruritic effect in a mouse model of allergic contact dermatitis by comparing anthocyanin-rich quality-controlled bilberry extract and anthocyanidin-rich degraded extract.

The study included BALB/c mice with allergic contact dermatitis induced by 4 weeks of repeated application of 2,4,6-trinitro-1-chlorobenzene (TNCB) were administered Bilberon-25 orally for 4 weeks after sensitization with TNCB.

Treatment with non-heated Bilberon-25 significantly attenuated the TNCB-induced increased scratching behavior, whereas treatment with 2 h-heated Bilberon-25 did not.

300 μg/mL nonheated Bilberon-25 showed significant inhibition of degranulation in RBL-2H3 mast cells, whereas 2 h-heated Bilberon-25 had no effect at any concentration.

Further differentiation of the results, researchers found that the efficacy of nonheated Bilberon-25 was attributed to the inhibitory effect of bilberry anthocyanins on pruritus mediated, at least in part, on mast cell degranulation.

More precisely, Dr. Yamaura K, the lead scientist said, "the anthocyanin-rich but not anthocyanidin-rich bilberry extract may be a useful dietary supplement for skin diseases involving pruritic symptoms, such as chronic allergic contact dermatitis, atopic dermatitis, and rhinitis".

Furthermore, in a mouse model induced chronic allergic contact dermatitic researchers once again examined the bilberry extract (Bilberon-25) in the alleviation of pruritus.

The study included BALB/c mice with chronic allergic contact dermatitis induced by 3 weeks of repeated application of 2,4,6-trinitro-1-chlorobenzene (TNCB) were administered Bilberon-25 orally for 3 weeks after sensitization with TNCB.


During the study, treatment with Bilberon-25 significantly attenuated the TNCB-induced increased scratching behavior, but dexamethasone did not.

Both dexamethasone and Bilberon-25 showed a significant amelioration of ear swelling.

Base on these results, researchers wrote in the final report, "Anthocyanins from bilberry might be beneficial for the treatment of chronic pruritus which can occur in patients with inflammatory skin diseases such as atopic dermatitis".

Taken altogether, bilberry processed a high amount of anthocyanins may be considered a functional food for the treatment of chronic pruritus with no side effects, pending to the confirmation of larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anthocyanins, but not anthocyanidins, from bilberry (Vaccinium myrtillus L.) alleviate pruritus via inhibition of mast cell degranulation by Yamaura K1, Ishiwatari M, Yamamoto M, Shimada M, Bi Y, Ueno K. (PubMed)
(2) Anthocyanins from bilberry (Vaccinium myrtillus L.) alleviate pruritus in a mouse model of chronic allergic contact dermatitis by Yamaura K1, Shimada M, Ueno K. (PubMed)
(3) Epidemiology of Itch by Elke Weisshaar and Uwe Matterne.(NCBI)

Bromelain Protects the Cardiac Muscle in Blood Circulation

Cardiac muscle or heart muscle or myocardium is a type of muscle that helps the heart to pump blood to nourish the entire body by performing the coordinated contractions.

Damage of heart muscle can lead to cardiomyopathy, or heart muscle disease, leading to abnormally heart enlarged, thickened, and/or stiffened.

In other words, cardiomyopathy reduced the heart muscle ability to pump blood, causing heart failure and the backup of blood into the lungs or the rest of the body.

Most common types of cardiomyopathy are
* Dilated cardiomyopathy is a condition caused by the enlarged and weakened the left ventricle.

* Hypertrophic cardiomyopathy is a result of the thickening of the heart muscle, at the septum between the ventricles, below the aortic valve.

* Ischemic cardiomyopathy is the condition caused by narrow arteries that affect the supply blood to the heart muscle.

* Restrictive cardiomyopathy is a condition that the walls of the lower chambers of the ventricles are too rigid to expand

Most common symptoms of cardiomyopathy are associated with reduce blood flow due to reduced function of heart muscle including general weakness and fatigue, shortness of breath, particularly during exertion or exercise, lightheadedness, and dizziness, chest pain, heart palpitations, fainting attacks, high blood pressure, edema, or swelling, of your feet, ankles, and legs.

If you have experienced some of the aforementioned symptoms, please check with your doctor to rule out the possibility of cardiomyopathy.

Out of many factors associated with the risk of cardiomyopathy, some researchers suggested that long-term alcoholism may be the major culprit.

Dr. B. Maisch wrote, " Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke".


However, "More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites".

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

With an aim to find a potential ingredient for the improvement of cardiovascular circulation, researchers examined the effect of bromelain on ischemia/reperfusion (IR) injury is characterized by the production of oxygen-free radicals leading to disturbances in vasomotility (microvascular constriction) and microvascular permeability (interstitial edema formation).

The study included a rabbit hindlimb model of I/R (2.5/2 h) were given Phlogenzym, containing rutin, trypsin, and bromelain enterally (60 mg/kg body weight) 30 min prior to ischemia (Ph group).

Before treatment with Phlogenzym, two hours after reperfusion, potassium levels were significantly elevated in IR compared to the Ph group.

Application of Phlogenzym inhibited the enhanced lipid peroxidation, apparent by increased plasma malondialdehyde levels in the Ph group, particularly, in the reduction of blood flow.


Furthermore, Phlogenzym treatment also prevented microvascular constriction and mollified interstitial edema

In other words, Phlogenzym protects the cardiac muscle in blood circulation against damage caused by ischemia/reperfusion (I/R) injury.

Based on the findings, researchers wrote, "Phlogenzym had a protective effect on skeletal muscle during I/R injury expressed by prevention of no-reflow and preservation of muscle tissue".

Taken altogether, bromelain used alone or combined with conventional medicine may be considered a remedy for the protection of heart muscle, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
Bromelain Osteoarthritis
(1) Properties and Therapeutic Application of Bromelain: A Review by Rajendra Pavan, Sapna Jain, Shraddha, and Ajay Kumar. (PMC)
(2) The result of dosage and individual predisposition. Alcoholic cardiomyopathy by B. Maisch. (PMC)

Topical Arnica Gel, Better Than Non-Steroidal Anti-Inflammatory Medications in Accelerated Ecchymosis Healing

Arnica may have a potential and therapeutic effect in reduced expression of Ecchymosis, some scientists suggested.

The results of this efficacy were confirmed by some studies conducted by numbers of respectable institutes, including the University of Miami Miller School of Medicine and the University of South Florida.

Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases, it is caused by bruising.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.

In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who underwent rhinoplasty, the most common facial plastic surgical procedure, researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).


According to the final search of 11 trials satisfied the criteria and guideline with a total of 627 patients, the application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in comparison to the control group.

However, eyelid ecchymosis during the first 24 h postoperatively was statistically decreased in the cold compression group compared to the control group.

Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.

Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than in the control group.

Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis compared to non-packing.

Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers conducted a review examined the postoperative course of healthy volunteers using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012, to December 31, 2012, using medical records review.

A total of 27 patients (16 females, 11 males) with an age range of 18 to 70 years were included in the study.

The selected medical review showed that patients included had used topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) applied bilaterally after surgery through postoperative day 6 at each postoperative visit.

The results of everyday progression in patients were evaluated by their respective surgeons and assigned a subjective physician-patient rating score comparing each patient's observed healing compared with expected healing if not using Arnica/Ledum.


Photographs in each examination also were recorded. The median duration of follow-up was 7 days, range from 1 to 14 days.

According to the rating of physician examined the results, the proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.

The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.


The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly more than the proportion of those demonstrating no appreciable difference from expected at (postoperative day) POD 3 to 5 (85.7% vs. 0%, p = 0.05), POD 6 to 8 (60.0% vs. 10.0%), and overall (51.9% vs. 11.1%, p = 0.05) without inducing any adverse effects.


Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis...., after oculofacial surgery".

Taken together, topical Arnica may be considered as a functional food to accelerated the healing of ecchymosis

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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)

Green tea Bioactive Compound Theanine Which Protects the Brain Against Manic and Depressive Episodes in Bipolar Disorder

Green tea major bioactive theanine may have a potential and positive effect in blocking the onset of bipolar disorder, some scientists suggested.

Bipolar disorder is a condition of brain disorder characterized by unusual shifting mood, energy, activity levels, and interfering the brain function in carrying out day-to-day tasks.

According to the National Institute of Mental Health, the conditions can be classified in to
* Bipolar I disorder with severe manic episodes last at least 7 days, most people with bipolar I disorder needs immediate hospital care.

* Bipolar II disorder is characterized by a pattern of depressive episodes and hypomanic episodes.

* Cyclothymic disorder also known as cyclothymia is a condition with numerous periods of hypomanic and depressive symptoms that lasting for at least 2 years.

*4. Other conditions that do not match the 3 above.

Dr. Steve Bressert, Ph.D. in the article Manic Episode Symptoms, wrote, "The symptoms of mania include: elevated mood, inflated self-esteem, decreased need for sleep, racing thoughts, difficulty maintaining attention, increase in goal-directed activity, and excessive involvement in pleasurable activities" compared to depressive episode that characterizes with low mood and other depression symptoms that lasts for 2 weeks or more. In some cases, a depressive episode may last several weeks or months at a time.


Green tea is a precious drink that processes a number of health benefits known to almost everyone in Asia and the Western world.

In the investigation to determine whether theanine (n-ethylglutamic acid), a non-proteinaceous amino acid component of green and black teas have any protective effects on the central nervous system, researchers found that
* Theanine exerts a variety of neurophysiological and pharmacological effects through crosses the blood-brain barrier.

* Application of theanine also demonstrates the anxiolytic and calming effect by up-regulation of inhibitory neurotransmitters and possible modulation of serotonin and dopamine in selected areas and increasing levels of the brain-derived neurotrophic factor.

* The bioactive compound also displays a neuroprotective effect following cerebral infarct and injury,

* Theanine also elicits improvements in cognitive function including learning and memory,

* Interestingly, theanine administration elicits selective changes in alpha brain wave activity with concomitant increases in selective attention during the execution of mental tasks and inhibits depression.


These results suggested that theanine can be considered a therapeutic role in the treatment of some psychiatric disorders such as anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), and bipolar disorder.

Additionally, in a study by Portland VA Medical Center of adults with schizophrenia, schizoaffective disorder or bipolar disorder who were maintained on antipsychotic and other psychotropic medications randomized to supplemental EGCG or placebo including a total of 34 participants (17 EGCG, 17 placebo) and 25 participants (14 EGCG, 11 placebo), researchers showed that

* Both treatment groups showed significant reductions in psychotic, depressive and anxiety symptoms from baseline to end of treatment.

* However, EGCG did not significantly affect psychiatric symptoms or inflammatory markers, as compared with placebo.

* Adverse effects were mild and comparable between groups.

The finding indicated that green tea extract EGCG exerts an insignificant effect on psychiatric symptoms in patients with bipolar disorder compared to Theanine, another major ingredient in green and black tea.

Taken all together, green and black tea major bioactive theanine may be considered a secondary therapy in protecting the brain against manic and depressive episodes in patients with bipolar disorder.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of epigallocatechin gallate supplementation in schizophrenia and bipolar disorder: an 8-week, randomized, double-blind, placebo-controlled study by Loftis JM1, Wilhelm CJ, Huckans M.(PubMed)
(2) Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders by Lardner AL. (PubMed)

Betaxanthins, the Antioxidant Phytochemicals

Antioxidants are stable atoms which inhibit oxidation caused by free radical.

Antioxidants besides produced by the body, they can also come into the body from the dietary sources, including second metabolites found in fruits and vegetables.

Free radical scavengers are types of antioxidants that inhibit free radicals before they can induce a chain of reaction, leading to the onset of oxidative stress.

Oxidative stress associated with chronic disease is caused by a long-term imbalanced ratio of free radicals and antioxidants. Oxidative stress has been found epidemiologically to induce proteins, lipids, and cellular damage, a major cause of heart disease, stroke, and diabetes.

Not all free radicals are bad, in a moderate amount, free radicals are necessary for the body functioning, including the promotion of heart function in blood circulation.

In a healthy individual, antioxidant enzymes produced by the liver are more than enough to counter the expression of free radicals induced by cell metabolism and the environment such as the air we breathe and the food we eat.

However, people with a weakened immune system, intake of antioxidants from outside sources such as fruits and vegetables can be helpful.

Most common types of free radical scavengers produced by the human are catalases that protect the cell from oxidative damage by decomposed hydrogen peroxide to water and oxygen, glutathione peroxidase, a cytosolic enzyme produced by the body that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen, and superoxide dismutase (SOD) that dissolves superoxide radical into either ordinary molecular oxygen or hydrogen peroxide.

Dr. V. Hajhashemi, the lead scientist wrote, "Free radicals are produced continuously in the cells as part of normal cellular function, however, excess production might play a role in the pathophysiology of many disease conditions, including cancer, Alzheimer's disease, atherosclerosis and some of the drug-induced toxicity".
And, " Many basic research studies and observational epidemiologic studies in humans suggest that antioxidants can prevent oxidative damage".


Betaxanthins are Phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, Sicilian prickly pear, etc.

On finding a potent ingredient for the prevention of heart diseases associated with oxidative stress, researchers investigated the effects of beetroot juice (BTJ) and whole beetroot (BF) on high blood pressure.

The randomized, crossover design study included a total of 10 healthy males consumed either 250 ml of BTJ, 300 g of BF or a placebo drink.


According to the sample analysis,
* Trolox equivalent antioxidant capacity (TEAC) was 11.4 ± 0.2 mmol/L for BTJ compared to 3.4 ± 0.4 μmol/g of BF.

* Both BTJ and BF contained a number of polyphenols (1606.9 ± 151 mg/GAE/L and 1.67 ± 0.1 mg/GAE/g, respectively)



* Betaxanthins exerted a TEAC of 41.7 ± 0.7 mg/indicaxanthin equivalents/L and 7.5 ± 0.2 mg/indicaxanthin equivalents/100 g, respectively comapred to betacyanins of 68.2 ± 0.4 mg/betanin equivalents/L and 19.6 ± 0.6 mg/betanin equivalents/100 g, respectively.


* Betanin contents the highest TEAC in both BTJ (~194 mg) and BF (~66 mg), betanin could not be detected in the plasma at any time point post-ingestion compared to other chemical compounds.

In other words, beetroot juice (BTJ) and whole beetroot (BF) showed high levels of antioxidants associated with increasing plasma NOx bioavailability.

Taken altogether, betaxanthins second to betacyanins may be considered an antioxidant remedy for the inhibition of free radicals, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The plasma bioavailability of nitrate and betanin from Beta vulgaris rubra in humans by Clifford T1, Constantinou CM2, Keane KM2, West DJ3, Howatson G2,4, Stevenson EJ. (PubMed)
(2) Are antioxidants helpful for disease prevention? by V. Hajhashemi,1,* G. Vaseghi,1 M. Pourfarzam,2 and A. Abdollahi. (PMC)