Ginger may have a profound effect in reducing the risk and treatment of hepatic steatosis, the early stage of liver disease, some scientists suggested.
Hepatic steatosis or fatty liver is a condition that caused excess fat accumulated in the liver.
At the early stage of hepatic steatosis, the patient may not experience any symptoms. However, at the condition of progress, the condition induces liver inflammation, which may progress to scarring and irreversible damage. Patients at this stage can have symptoms of abdominal swelling, enlarged blood vessels in the skin and spleen accompanied by jaundice.
The most common risk factors are the increase in age, (older than 45 years of age). overweight and obesity and ethnicity.
However, some researchers suggested the coincidence of widespread obesity and the onset of hepatic steatosis might indicate a closed correlation of the e2 conditions.
Dr. Festi D, the lead author in the finding the relation between obesity and hepatic steatosis that causes a wide spectrum of liver damage as simple steatosis may progress to advanced fibrosis and to cryptogenic cirrhosis through steatohepatitis launched an investigation to examine the risk of hepatic steatosis in obese patients.
After taking account co and confounders wrote, "Obesity is the most significant single risk factor for the development of fatty liver, both in children and in adults; obesity is also predictive of the presence of fibrosis, potentially progressing to advanced liver disease".
The risk of the fatty liver may be associated with insulin resistance in the obese patients that play a central role in the accumulation of triglycerides within the hepatocytes and in the initiation of the inflammatory cascade.
Although conventional treatment with insulin-sensitizing agents, anti-oxidants or cytoprotective drugs may be useful, however, they are no randomized clinical trials to support the efficacy.
As of today, there is no direct treatment of hepatic steatosis but relieve the symptoms.
Some researchers suggested, modifications in lifestyle (e.g. diet and exercise) to reduce obesity remain the mainstay of prevention and treatment of a disease,
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
It has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In finding a natural whole food that may have a potent to prevent and treat nonalcoholic fatty liver, researchers at the Tajen University, Yanpu Township investigate the effects of [6]-gingerol ((S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone) in experimental models of the non-alcoholic fatty liver.
[6]-Gingerol (100 µmol/l) inhibited OA-induced triglyceride and inflammatory marker accumulation in HepG2 cells.
In the study of male golden hamsters were dosed orally with [6]-gingerol (25, 50 or 100 mg/kg/day) once daily for 8 weeks after being fed a high-fat diet (HFD) for 2 weeks, injection of [6]-Gingerol (100 mg/kg/day) alleviated liver steatosis, inflammation, and reversed plasma markers of metabolic syndrome in HFD-fed hamsters.
[6]-gingerol also attenuated the expression of inflammatory cytokine genes and nuclear transcription factor-κB (NF-κB) increased in the HFD group.
These results indicated a significant effect of [6]-Gingerol in the attenuation of the HFD-induced steatohepatitis by downregulating NF-κB-mediated inflammatory responses and reducing hepatic lipogenic gene expression.
Additionally, in the concern of widespread Nonalcoholic fatty liver disease (NAFLD) may reach epidemic proportions, Dr. Sahebkar A. launched a study to evaluate the ginger effect at the "two-stage hypothesis" proposed for the pathophysiology of NAFLD, insulin resistance, oxidative stress and pro-inflammatory cytokines among the key promoters of the disease.
Application of ginger prevent NAFLD or blunt its progression via several mechanisms, such as sensitizing insulin effects, and down-regulates pro-inflammatory cytokines.
Ginger promoted considerable antioxidant effects and antidyslipidemic properties and reduced hepatic triglyceride content which can prevent steatosis.
All these mechanisms suggested that ginger possesses interesting potentials for serving as a natural supplement for the prevention and treatment of NAFLD.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [6]-gingerol dampens hepatic steatosis and inflammation in experimental nonalcoholic steatohepatitis by Tzeng TF1, Liou SS1, Chang CJ1, Liu IM. (PubMed)
(2) Potential efficacy of ginger as a natural supplement for nonalcoholic fatty liver disease by Sahebkar A. (PubMed)
(3) Hepatic steatosis in obese patients: clinical aspects and prognostic significance by Festi D1, Colecchia A, Sacco T, Bondi M, Roda E, Marchesini G.(PubMed)
Monday, February 3, 2020
Herbal Bilberry Reduces Risk of Macular Degeneration
Macular degeneration is a condition caused by the deterioration of the small central portion of the retina, known as the macula.
Macular degeneration happened mostly in adults over 60, is one of the major cause of vision loss.
The exact causes of macular degeneration are not identified. As of today, researchers cannot explain why some elderly are susceptible to macular degeneration while others do not.
There are 2 forms of macular degeneration
1. The dry form is caused by the presence of yellow deposits, called drusen under the retina, in the macula. However, the elderly with increased was not at a higher risk of macular degeneration.
2. The wet form is caused by the growth of abnormal blood vessels from the choroid, the vascular layer of the eye, underneath the retina.
Compared to the loss of vision of 10% of patients induced by the wet form, most patients of macular degeneration have the dry form which has been found to cause loss of some central vision.
Although aging is one the prevalent risk of the macular degeneration onset, smoking, family history, gender, ethnicity and long-term exposure to the sun and genetic preposition are also some factors may facilitate the early onset of the condition.
Some researchers suggested that macular degeneration may also be caused by an unhealthy diet.
Dr. Chung-Jung Chiu, the lead scientist in the analysis of the relationship of major American dietary patterns to age-related macular degeneration wrote, " (In the comparison of the 2 diets pattern) The Oriental pattern was characterized by higher intake of vegetables, legumes, fruit, whole grains, tomatoes, and seafood. The Western pattern was characterized by higher intake of red meat, processed meat, high-fat dairy products, French fries, refined grains, and eggs".
"For early AMD, multivariate-adjusted odds ratio (OR) from generalized estimating equation logistic analysis comparing the highest to lowest quintile of the Oriental pattern score was ORE5O=0.74 (95% confidence interval (CI): 0.59–0.91; Ptrend=0.01), and the OR comparing the highest to lowest quintile of the Western pattern score was ORE5W=1.56 (1.18–2.06; Ptrend=0.01). For advanced AMD, the ORA5O was 0.38 (0.27–0.54; Ptrend<0.0001), and the ORA5W was 3.70 (2.31–5.92; Ptrend<0.0001)".
These results strongly suggested the risk of AMD is many folds higher in people who follow the Western diet compared to those who follow the Oriental diet.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Searching the list of natural compounds for the treatment of vision decline, scientists examined anthocyanins, bioactive compounds found in bilberry are known to have antioxidant, anti-inflammatory, on macular degeneration.
Bilberry anthocyanosides (Vaccinium myrtillus L.), according to the differentiation was found to promote rhodopsin synthesis and regeneration, thus increasing the retinal sensitivity to changes in light intensity and visual acuity and dark adaptation.
The bioactive compound also was found to the promoted blood supply of the retina in the prevention of macular degeneration due to aging-induced death of macula cells.
Where rhodopsin is the pigment-containing sensory protein that converts light into an electrical signal for vision in dim light
The improvement of the visual function by bilberry may have a strong effect against age-related macular degeneration, Dr. Vorob'eva IV, the lead scientists suggested.
Additionally, with an aim to reveal more information of bilberry anti gradual loss of vision, researchers investigated the changes in clinical, functional, and morphological parameters of the retina in type 2 diabetes patients with diabetic retinopathy (DR) and those with combined fundus pathology (DR plus age-related macular degeneration).
The study included 180 patients (180 eyes) with type 2 diabetes divided into 6 groups of 30 each randomly assigned into group 1 consisted of patients with DRO,; group 2--DR1 without DM, group 3--DR1 with DM, group 4--DRO and "dry" AMD (AREDS 1-3), group 5--DR1 with no DM but with AMD (AREDS 1-3), and group 6--DR1 with DM and AMD (AREDS 1-3).
A drug-containing lutein 6 mg, zeaxanthin 0.5 mg, vitamin C 60 mg, vitamin E 7 mg, vitamin A 1.5 mg, vitamin B2 1.2 mg, rutin 25 mg, zinc 5 mg, Selenium 25 mcg, and bilberry extract 60 mg was used for antioxidative therapy. Ginkgo biloba leaf extracts 60 mg was chosen as the radioprotector.
At the end of the experiment, researchers found that
* Macular thickness was statistically significant only in 3 and 6 (p<0.05)compared to only slight changes on other groups and light sensitivity of the macula showed a reduction, which was statistically significant in groups 4-6 before treatment.
* Injection of the supplements antioxidant and angio-protective activities displayed a strong improvement of all parameters related to visual decline, including increased visual acuity.
Dr. the lead scientist wrote in the final report, "a combined antioxidant and double-dose angio-protective (240 mg) therapy appeared to be the most effective and can be considered not only a preventive but also a therapeutic measure in type 2 diabetes patients with initial stages of DR (DRO, DR1) or those with DR and DM or combined DR and AMD (AREDS 1-3)".
Taken altogether, bilberry may be considered a herbal remedy for the improvement of visual decline, particularly, in patients with macular degeneration, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(2) [Current data on the role of anthocyanosides and flavonoids in the treatment of eye diseases].[Article in Russian; Abstract available in Russian from the publisher] by Vorob'eva IV1, Vorob'eva IV. (PubMed)
(1) [Results of the use of antioxidant and angioprotective agents in type 2 diabetes patients with diabetic retinopathy and age-related macular degeneration].[Article in Russian; Abstract available in Russian from the publisher] by Moshetova LK1, Vorob'eva IV1, Alekseev IB1, Mikhaleva LG. (PubMed)
(3) The Relationship of Major American Dietary Patterns to Age-related Macular Degeneration by Chung-Jung Chiu, DDS, PhD, Min-Lee Chang, MS, Fang Fang Zhang, PhD, Tricia Li, MS, Gary Gensler, MS, Molly Schleicher, BS, and Allen Taylor, PhD. (PMC)
Macular degeneration happened mostly in adults over 60, is one of the major cause of vision loss.
The exact causes of macular degeneration are not identified. As of today, researchers cannot explain why some elderly are susceptible to macular degeneration while others do not.
There are 2 forms of macular degeneration
1. The dry form is caused by the presence of yellow deposits, called drusen under the retina, in the macula. However, the elderly with increased was not at a higher risk of macular degeneration.
2. The wet form is caused by the growth of abnormal blood vessels from the choroid, the vascular layer of the eye, underneath the retina.
Compared to the loss of vision of 10% of patients induced by the wet form, most patients of macular degeneration have the dry form which has been found to cause loss of some central vision.
Although aging is one the prevalent risk of the macular degeneration onset, smoking, family history, gender, ethnicity and long-term exposure to the sun and genetic preposition are also some factors may facilitate the early onset of the condition.
Some researchers suggested that macular degeneration may also be caused by an unhealthy diet.
Dr. Chung-Jung Chiu, the lead scientist in the analysis of the relationship of major American dietary patterns to age-related macular degeneration wrote, " (In the comparison of the 2 diets pattern) The Oriental pattern was characterized by higher intake of vegetables, legumes, fruit, whole grains, tomatoes, and seafood. The Western pattern was characterized by higher intake of red meat, processed meat, high-fat dairy products, French fries, refined grains, and eggs".
"For early AMD, multivariate-adjusted odds ratio (OR) from generalized estimating equation logistic analysis comparing the highest to lowest quintile of the Oriental pattern score was ORE5O=0.74 (95% confidence interval (CI): 0.59–0.91; Ptrend=0.01), and the OR comparing the highest to lowest quintile of the Western pattern score was ORE5W=1.56 (1.18–2.06; Ptrend=0.01). For advanced AMD, the ORA5O was 0.38 (0.27–0.54; Ptrend<0.0001), and the ORA5W was 3.70 (2.31–5.92; Ptrend<0.0001)".
These results strongly suggested the risk of AMD is many folds higher in people who follow the Western diet compared to those who follow the Oriental diet.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Searching the list of natural compounds for the treatment of vision decline, scientists examined anthocyanins, bioactive compounds found in bilberry are known to have antioxidant, anti-inflammatory, on macular degeneration.
Bilberry anthocyanosides (Vaccinium myrtillus L.), according to the differentiation was found to promote rhodopsin synthesis and regeneration, thus increasing the retinal sensitivity to changes in light intensity and visual acuity and dark adaptation.
The bioactive compound also was found to the promoted blood supply of the retina in the prevention of macular degeneration due to aging-induced death of macula cells.
Where rhodopsin is the pigment-containing sensory protein that converts light into an electrical signal for vision in dim light
The improvement of the visual function by bilberry may have a strong effect against age-related macular degeneration, Dr. Vorob'eva IV, the lead scientists suggested.
Additionally, with an aim to reveal more information of bilberry anti gradual loss of vision, researchers investigated the changes in clinical, functional, and morphological parameters of the retina in type 2 diabetes patients with diabetic retinopathy (DR) and those with combined fundus pathology (DR plus age-related macular degeneration).
The study included 180 patients (180 eyes) with type 2 diabetes divided into 6 groups of 30 each randomly assigned into group 1 consisted of patients with DRO,; group 2--DR1 without DM, group 3--DR1 with DM, group 4--DRO and "dry" AMD (AREDS 1-3), group 5--DR1 with no DM but with AMD (AREDS 1-3), and group 6--DR1 with DM and AMD (AREDS 1-3).
A drug-containing lutein 6 mg, zeaxanthin 0.5 mg, vitamin C 60 mg, vitamin E 7 mg, vitamin A 1.5 mg, vitamin B2 1.2 mg, rutin 25 mg, zinc 5 mg, Selenium 25 mcg, and bilberry extract 60 mg was used for antioxidative therapy. Ginkgo biloba leaf extracts 60 mg was chosen as the radioprotector.
At the end of the experiment, researchers found that
* Macular thickness was statistically significant only in 3 and 6 (p<0.05)compared to only slight changes on other groups and light sensitivity of the macula showed a reduction, which was statistically significant in groups 4-6 before treatment.
* Injection of the supplements antioxidant and angio-protective activities displayed a strong improvement of all parameters related to visual decline, including increased visual acuity.
Dr. the lead scientist wrote in the final report, "a combined antioxidant and double-dose angio-protective (240 mg) therapy appeared to be the most effective and can be considered not only a preventive but also a therapeutic measure in type 2 diabetes patients with initial stages of DR (DRO, DR1) or those with DR and DM or combined DR and AMD (AREDS 1-3)".
Taken altogether, bilberry may be considered a herbal remedy for the improvement of visual decline, particularly, in patients with macular degeneration, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(2) [Current data on the role of anthocyanosides and flavonoids in the treatment of eye diseases].[Article in Russian; Abstract available in Russian from the publisher] by Vorob'eva IV1, Vorob'eva IV. (PubMed)
(1) [Results of the use of antioxidant and angioprotective agents in type 2 diabetes patients with diabetic retinopathy and age-related macular degeneration].[Article in Russian; Abstract available in Russian from the publisher] by Moshetova LK1, Vorob'eva IV1, Alekseev IB1, Mikhaleva LG. (PubMed)
(3) The Relationship of Major American Dietary Patterns to Age-related Macular Degeneration by Chung-Jung Chiu, DDS, PhD, Min-Lee Chang, MS, Fang Fang Zhang, PhD, Tricia Li, MS, Gary Gensler, MS, Molly Schleicher, BS, and Allen Taylor, PhD. (PMC)
Herbal Butterbur and Airway inflammation
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere. It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
Airway inflammation is the inflammation of the airway as a result of other conditions include asthma, chronic bronchitis, bronchiectasis, and cystic fibrosis.
The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.
The benefits
Petasites japonicus (Pj), the giant butterbur has been used in traditional Oriental medicine for treating asthma, oxidant stress, and gastric ulcer. It extracts has exerted its suppressive properties for the pathogenesis of airway inflammation and may be considered a potent agent for the treatment of asthma. Other in the study of Petasites extract Ze 339 (PET) of herbal Petasites hybridus (butterbur) showed to inhibit leukotriene activity, reduce allergic airway inflammation and AHR by inhibiting the production of the Th2 cytokines IL-4 and IL-5, and RANTES.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Side effects
1. Butterbur may be liver-toxic to the liver and cause cancer due to the presence of pyrrolizidine alkaloids(a)
2. If you are pregnant please do not use Butterbur without the permission of the related special field specialist
3. Allergic effect on certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
References
(1) Suppressive effect of Petasites japonicus extract on ovalbumin-induced airway inflammation in an asthmatic mouse model by Lee JS, Yang EJ, Yun CY, Kim DH, Kim IS.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
Airway inflammation is the inflammation of the airway as a result of other conditions include asthma, chronic bronchitis, bronchiectasis, and cystic fibrosis.
The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.
The benefits
Petasites japonicus (Pj), the giant butterbur has been used in traditional Oriental medicine for treating asthma, oxidant stress, and gastric ulcer. It extracts has exerted its suppressive properties for the pathogenesis of airway inflammation and may be considered a potent agent for the treatment of asthma. Other in the study of Petasites extract Ze 339 (PET) of herbal Petasites hybridus (butterbur) showed to inhibit leukotriene activity, reduce allergic airway inflammation and AHR by inhibiting the production of the Th2 cytokines IL-4 and IL-5, and RANTES.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Side effects
1. Butterbur may be liver-toxic to the liver and cause cancer due to the presence of pyrrolizidine alkaloids(a)
2. If you are pregnant please do not use Butterbur without the permission of the related special field specialist
3. Allergic effect on certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
References
(1) Suppressive effect of Petasites japonicus extract on ovalbumin-induced airway inflammation in an asthmatic mouse model by Lee JS, Yang EJ, Yun CY, Kim DH, Kim IS.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
Herbal Therapy: Cayenne, the Natural Whole Herb for Antimicrobial Infection
Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced many interests in today renowned scientists.
But many researchers have raised the question of herbal quality, because geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experienced herbalists.
Cayenne may be the next antimntimicrobial natural whole foods used for the prevention and treatment of infection, inflammation and the common cold.
According to the joint study led by the Universidad Michoacana de San Nicolás de Hidalgo, cayenne exhibited a broad-spectrum antimicrobial action, through its' immunomodulatory roles of mammal β-defensins(antimicrobial peptides) in regulated inflammation and activated the immune system.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
Thionins, a chemical compound found in cayenne is considered as antimicrobial peptides (AMPs), which regulate plant defense system against pathogens. such as Candida species, with IC50 ranging from 10 to 40 μg.mL(-1).
The chemical compound also exhibited anti antimicrobial effect through its antioxidant activity against oxidative stresses. In bacteria and yeasts induced infection and inflammatory diseases, it exhibited toxicity and induced changes in the membranes of all yeast strains, leading to their permeabilization.
Dr. Diz MS, the lead author in the study peptides from chili pepper seeds, said, " F1(peptides from chili pepper (Capsicum annuum L.) seeds) fraction exhibited strong fungicidal activity against Candida albicans, Saccharomyces cerevisiae and Schizosaccharomyces pombe and also promoted several morphological changes to C. Albicans".
In some yeast species, peptides isolated from cayenne also inhibited the growth of yeasts Saccharomyces cerevisiae, Candida albicans, Candida parapsilosis, Candida tropicalis, Pichia membranifaciens,
Intake of cayenne may improve the immunomodulatory activity in the body against microbial organisms induced infection and inflammation, but quantity intake should only be given by herbalist for prevention of overdoses' toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
(2) Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species by Taveira GB1, Carvalho AO2, Rodrigues R3, Trindade FG4, Da Cunha M5, Gomes VM6(PubMed)
(3) Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts by Taveira GB1, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM.(PubMed)
(4) Antimicrobial peptides from chili pepper seeds causes yeast plasma membrane permeabilization and inhibits the acidification of the medium by yeast cells by Diz MS1, Carvalho AO, Rodrigues R, Neves-Ferreira AG, Da Cunha M, Alves EW, Okorokova-Façanha AL, Oliveira MA, Perales J, Machado OL, Gomes VM.(PubMed)
But many researchers have raised the question of herbal quality, because geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experienced herbalists.
Cayenne may be the next antimntimicrobial natural whole foods used for the prevention and treatment of infection, inflammation and the common cold.
According to the joint study led by the Universidad Michoacana de San Nicolás de Hidalgo, cayenne exhibited a broad-spectrum antimicrobial action, through its' immunomodulatory roles of mammal β-defensins(antimicrobial peptides) in regulated inflammation and activated the immune system.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
Thionins, a chemical compound found in cayenne is considered as antimicrobial peptides (AMPs), which regulate plant defense system against pathogens. such as Candida species, with IC50 ranging from 10 to 40 μg.mL(-1).
The chemical compound also exhibited anti antimicrobial effect through its antioxidant activity against oxidative stresses. In bacteria and yeasts induced infection and inflammatory diseases, it exhibited toxicity and induced changes in the membranes of all yeast strains, leading to their permeabilization.
Dr. Diz MS, the lead author in the study peptides from chili pepper seeds, said, " F1(peptides from chili pepper (Capsicum annuum L.) seeds) fraction exhibited strong fungicidal activity against Candida albicans, Saccharomyces cerevisiae and Schizosaccharomyces pombe and also promoted several morphological changes to C. Albicans".
In some yeast species, peptides isolated from cayenne also inhibited the growth of yeasts Saccharomyces cerevisiae, Candida albicans, Candida parapsilosis, Candida tropicalis, Pichia membranifaciens,
Intake of cayenne may improve the immunomodulatory activity in the body against microbial organisms induced infection and inflammation, but quantity intake should only be given by herbalist for prevention of overdoses' toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
(2) Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species by Taveira GB1, Carvalho AO2, Rodrigues R3, Trindade FG4, Da Cunha M5, Gomes VM6(PubMed)
(3) Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts by Taveira GB1, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM.(PubMed)
(4) Antimicrobial peptides from chili pepper seeds causes yeast plasma membrane permeabilization and inhibits the acidification of the medium by yeast cells by Diz MS1, Carvalho AO, Rodrigues R, Neves-Ferreira AG, Da Cunha M, Alves EW, Okorokova-Façanha AL, Oliveira MA, Perales J, Machado OL, Gomes VM.(PubMed)
Sunday, February 2, 2020
Herbal cayenne Normalizes the Levels of High Blood Cholesterol with No Side Effects, According to Studies
Herbal Cayenne processed a high amount of bioactive compound capsaicinoids that may have a strong and potential effect in reducing levels of high blood cholesterol, according to studies.
Hyperlipidemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.
Dr. Joan Carles Escolà-Gil and colleagues in the concern about the Western diet pattern in risk of high blood cholesterol wrote, "The HFHC diet caused a significant increase in plasma cholesterol, HDL cholesterol, and liver cholesterol and enhanced macrophage-derived [3H]cholesterol flux to feces by 3- to 4-fold, (in tested mice)".
And, " The HFHC diet caused 1.4- and 3-fold increases in [3H]cholesterol efflux to plasma and HDL-derived [3H]tracer fecal excretion".
The results strongly indicated there is a clinical significance of a high-fat diet in the increased substantially risk of high blood cholesterol.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
The herbal medicine has been used in traditional medicine to increases metabolism, enhance the circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.
Researchers on finding herbal medicine for the treatment of high blood cholesterol examined the antihyperlipidemic effects of capsaicinoids, the active compounds in chili pepper.
Hamsters selected to the study were divided into five groups and fed a high-cholesterol diet containing 0 % (CON), 0.010 % (LD), 0.015 % (MD), 0.020 % (HD), and 0.030 % (VD) capsaicinoids, respectively, for 6 weeks.
Capsaicinoids reduced plasma total cholesterol, non-high-density lipoprotein, and triacylglycerols without affecting the levels of high-density lipoprotein.
Dietary capsaicinoids increased the fecal excretion of total acidic sterols possibly associated with an enzyme which oxidizes cholesterol and inhibited the liver X receptor alpha which was found to raised HDL-cholesterol and increased liver triglycerides in a wild-type mice study.
Furthermore, capsaicinoids not only decreased cholesterol absorption but also improved the levels of expression of COX-2 associated with the accumulation of lipids in circulation and liver, and lipid peroxidation in case of deficiency.
Dr. Liang YT, the lead scientist, after taking into account co and confounders wrote, "Capsaicinoids were beneficial in improving lipoprotein profile and aortic function in hamsters fed a high-cholesterol diet".
Moreover, in female ovariectomized Sprague-Dawley rats, the sham group and OVX control group were fed with high-cholesterol diets, whereas the treatment group (control diet containing 0.01% capsaicinoids) was fed with high-cholesterol plus 0.01% capsaicinoids diet for 21 days.
Injection of capsaicinoids significantly decreased the body weight gain, plasma total cholesterol, LDL cholesterol, and triacylglycerol without affecting the high-density lipoprotein cholesterol in the OVX rats.
These changes in plasma lipoprotein profile were accompanied by a greater excretion of total bile acid in feces and small intestinal contents.
The efficacy of the compound in the inhibition of high blood cholesterol was attributed to the significantly enhanced the expressions of hepatic cholesterol 7α-hydroxylase, an enzyme and receptor potential vanilloid type-1 associated with cholesterol oxidation.
Dr. Zhang L, the lead researchers wrote in the final report, "The hypocholesterolemic activity of capsaicinoids is caused by the stimulating conversion of cholesterol to bile acids by upregulation of cholesterol 7α-hydroxylase expression and the increase in fecal total bile acid excretion".
Taken altogether, herbal cayenne processed major bioactive ingredient capsaicinoids may be considered a function fruit for the prevention and treatment of high blood cholesterol, pending to the
larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters by Liang YT1, Tian XY, Chen JN, Peng C, Ma KY, Zuo Y, Jiao R, Lu Y, Huang Y, Chen ZY.(PubMed)
(2) The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis by Zhang L1, Fang G, Zheng L, Chen Z, Liu X.(PubMed)
(3) Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats by Zhang L1, Zhou M, Fang G, Tang Y, Chen Z, Liu X.(PubMed)
Hyperlipidemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.
Dr. Joan Carles Escolà-Gil and colleagues in the concern about the Western diet pattern in risk of high blood cholesterol wrote, "The HFHC diet caused a significant increase in plasma cholesterol, HDL cholesterol, and liver cholesterol and enhanced macrophage-derived [3H]cholesterol flux to feces by 3- to 4-fold, (in tested mice)".
And, " The HFHC diet caused 1.4- and 3-fold increases in [3H]cholesterol efflux to plasma and HDL-derived [3H]tracer fecal excretion".
The results strongly indicated there is a clinical significance of a high-fat diet in the increased substantially risk of high blood cholesterol.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
The herbal medicine has been used in traditional medicine to increases metabolism, enhance the circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.
Researchers on finding herbal medicine for the treatment of high blood cholesterol examined the antihyperlipidemic effects of capsaicinoids, the active compounds in chili pepper.
Hamsters selected to the study were divided into five groups and fed a high-cholesterol diet containing 0 % (CON), 0.010 % (LD), 0.015 % (MD), 0.020 % (HD), and 0.030 % (VD) capsaicinoids, respectively, for 6 weeks.
Capsaicinoids reduced plasma total cholesterol, non-high-density lipoprotein, and triacylglycerols without affecting the levels of high-density lipoprotein.
Dietary capsaicinoids increased the fecal excretion of total acidic sterols possibly associated with an enzyme which oxidizes cholesterol and inhibited the liver X receptor alpha which was found to raised HDL-cholesterol and increased liver triglycerides in a wild-type mice study.
Furthermore, capsaicinoids not only decreased cholesterol absorption but also improved the levels of expression of COX-2 associated with the accumulation of lipids in circulation and liver, and lipid peroxidation in case of deficiency.
Dr. Liang YT, the lead scientist, after taking into account co and confounders wrote, "Capsaicinoids were beneficial in improving lipoprotein profile and aortic function in hamsters fed a high-cholesterol diet".
Moreover, in female ovariectomized Sprague-Dawley rats, the sham group and OVX control group were fed with high-cholesterol diets, whereas the treatment group (control diet containing 0.01% capsaicinoids) was fed with high-cholesterol plus 0.01% capsaicinoids diet for 21 days.
Injection of capsaicinoids significantly decreased the body weight gain, plasma total cholesterol, LDL cholesterol, and triacylglycerol without affecting the high-density lipoprotein cholesterol in the OVX rats.
These changes in plasma lipoprotein profile were accompanied by a greater excretion of total bile acid in feces and small intestinal contents.
The efficacy of the compound in the inhibition of high blood cholesterol was attributed to the significantly enhanced the expressions of hepatic cholesterol 7α-hydroxylase, an enzyme and receptor potential vanilloid type-1 associated with cholesterol oxidation.
Dr. Zhang L, the lead researchers wrote in the final report, "The hypocholesterolemic activity of capsaicinoids is caused by the stimulating conversion of cholesterol to bile acids by upregulation of cholesterol 7α-hydroxylase expression and the increase in fecal total bile acid excretion".
Taken altogether, herbal cayenne processed major bioactive ingredient capsaicinoids may be considered a function fruit for the prevention and treatment of high blood cholesterol, pending to the
larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters by Liang YT1, Tian XY, Chen JN, Peng C, Ma KY, Zuo Y, Jiao R, Lu Y, Huang Y, Chen ZY.(PubMed)
(2) The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis by Zhang L1, Fang G, Zheng L, Chen Z, Liu X.(PubMed)
(3) Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats by Zhang L1, Zhou M, Fang G, Tang Y, Chen Z, Liu X.(PubMed)
Chaste Tree Berry in Reduced Risk and Treatment of Colon Cancer
Vitex agnus-castus fruit is found to process an anti irregular cell growth, the early stage of cancer development in colon, a university study suggested.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Colon cancer is a medical condition of the abnormal proliferation of cells in the large intestine.
According to the Tokyo University of Pharmacy & Life Sciences, treatment with chaste tree berry induced apoptosis of cancer cells not by the presence of antioxidants but an expression of antibody gene HO-1 in regulating oxidative stress.
Dr. Imai M, the lead researcher said. "Vitex treatment activates a pathway associated with HO-1 gene activation, resulting in the induction of apoptosis in COLO 201, (the colon cancer cell line)".
Additionally, in a novel strategy with biological approach for synthesis of silver nanoparticles (AgNPs), a toxic substance, using sodium para-hydroxybenzoate tetrahydrate (SPHT) isolated from Vitex negundo leaves, treatment of sodium para-hydroxybenzoate tetrahydrate (SPHT) improved the hydroxyl and carboxylic functional groups mediators in exhibited a stronger ability towards synthesis of AgNPs which indicated the apoptotic effect on human colon cancer cell lines.
The study also insisted that the extract displays an anti colon cancer activity confirmed by colorimetric assay, annexin V/Dead Cell Apoptosis and cell cycle analysis.
Furthermore, casticin, one of the major components of the fruits of chaste tree, showed a significantly induced apoptosis effect in of HT-29, HCT-116, SW480 and Caco-2 cells, reduced accumulation of reactive oxygen species (ROS) and increased the protein levels in regulation of cancer cell apoptosis and B-cell lymphoma activation of cell death of HT-29 cells, a colon cancer cell line.
Collectively, casticin also promoted Cell Death in cell division with the same mechanisms in other cancer cell lines, including HCT-116, SW480 and Caco-2 cells.
Taking together, chaste tree berry may be the next therapeutic treatment for reduced risk and treatment of colon cancer, but the injection of large quantity should only be prescribed by related field specialists.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance by Imai M1, Kikuchi H, Denda T, Ohyama K, Hirobe C, Toyoda H.(PubMed)
(2) Synthesis and characterization of silver nanoparticles using crystal compound of sodium para-hydroxybenzoate tetrahydrate isolated from Vitex negundo. L leaves and its apoptotic effect on human colon cancer cell lines by Durai P1, Chinnasamy A2, Gajendran B1, Ramar M1, Pappu S3, Kasivelu G4, Thirunavukkarasu A5.(PubMed)
(3) Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells by Qu L1, Liu FX1, Cao XC2, Xiao Q2, Yang X2, Ren KQ2.(PubMed)
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Colon cancer is a medical condition of the abnormal proliferation of cells in the large intestine.
According to the Tokyo University of Pharmacy & Life Sciences, treatment with chaste tree berry induced apoptosis of cancer cells not by the presence of antioxidants but an expression of antibody gene HO-1 in regulating oxidative stress.
Dr. Imai M, the lead researcher said. "Vitex treatment activates a pathway associated with HO-1 gene activation, resulting in the induction of apoptosis in COLO 201, (the colon cancer cell line)".
Additionally, in a novel strategy with biological approach for synthesis of silver nanoparticles (AgNPs), a toxic substance, using sodium para-hydroxybenzoate tetrahydrate (SPHT) isolated from Vitex negundo leaves, treatment of sodium para-hydroxybenzoate tetrahydrate (SPHT) improved the hydroxyl and carboxylic functional groups mediators in exhibited a stronger ability towards synthesis of AgNPs which indicated the apoptotic effect on human colon cancer cell lines.
The study also insisted that the extract displays an anti colon cancer activity confirmed by colorimetric assay, annexin V/Dead Cell Apoptosis and cell cycle analysis.
Furthermore, casticin, one of the major components of the fruits of chaste tree, showed a significantly induced apoptosis effect in of HT-29, HCT-116, SW480 and Caco-2 cells, reduced accumulation of reactive oxygen species (ROS) and increased the protein levels in regulation of cancer cell apoptosis and B-cell lymphoma activation of cell death of HT-29 cells, a colon cancer cell line.
Collectively, casticin also promoted Cell Death in cell division with the same mechanisms in other cancer cell lines, including HCT-116, SW480 and Caco-2 cells.
Taking together, chaste tree berry may be the next therapeutic treatment for reduced risk and treatment of colon cancer, but the injection of large quantity should only be prescribed by related field specialists.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance by Imai M1, Kikuchi H, Denda T, Ohyama K, Hirobe C, Toyoda H.(PubMed)
(2) Synthesis and characterization of silver nanoparticles using crystal compound of sodium para-hydroxybenzoate tetrahydrate isolated from Vitex negundo. L leaves and its apoptotic effect on human colon cancer cell lines by Durai P1, Chinnasamy A2, Gajendran B1, Ramar M1, Pappu S3, Kasivelu G4, Thirunavukkarasu A5.(PubMed)
(3) Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells by Qu L1, Liu FX1, Cao XC2, Xiao Q2, Yang X2, Ren KQ2.(PubMed)
Cat's claw, The best Whole Herb Medicine for Prevention and Treatment of Inflammatory diseases
Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
Inflammatory diseases are disorders and conditions caused by inflammation. Cat's claw may be the next generation of the medical plant for the treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through the interference of the pro-inflammatory expression.
Mitraphylline (MTP), the major pentacyclic oxindole alkaloid presented in Uncaria tomentosa, elicited an anti-inflammatory response that modulates neutrophil activation contributing to the attenuation of inflammatory episodes.
Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.
Indenture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.
In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to lesser production of PGE2, a principal mediator of inflammation in disease production.
The effects of cat's claw in inhibited inflammatory diseases may result from its binding to proinflammatory cytokines and pathways. The use of the medical plant should be only prescribed by herbal for safety purposes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes by Akhtar N1, Miller MJ, Haqqi TM.(PubMed)
(2) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils by Montserrat-de la Paz S1, Fernandez-Arche A2, de la Puerta R2, Quilez AM2, Muriana FJ3, Garcia-Gimenez MD2, Bermudez B4.(PubMed)
(3) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark by Rojas-Duran R1, González-Aspajo G, Ruiz-Martel C, Bourdy G, Doroteo-Ortega VH, Alban-Castillo J, Robert G, Auberger P, Deharo E.(PubMed)
(4) Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report by Tay LY1, Dos Santos FA, Jorge JH.(PubMed)
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
Inflammatory diseases are disorders and conditions caused by inflammation. Cat's claw may be the next generation of the medical plant for the treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through the interference of the pro-inflammatory expression.
Mitraphylline (MTP), the major pentacyclic oxindole alkaloid presented in Uncaria tomentosa, elicited an anti-inflammatory response that modulates neutrophil activation contributing to the attenuation of inflammatory episodes.
Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.
Indenture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.
In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to lesser production of PGE2, a principal mediator of inflammation in disease production.
The effects of cat's claw in inhibited inflammatory diseases may result from its binding to proinflammatory cytokines and pathways. The use of the medical plant should be only prescribed by herbal for safety purposes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes by Akhtar N1, Miller MJ, Haqqi TM.(PubMed)
(2) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils by Montserrat-de la Paz S1, Fernandez-Arche A2, de la Puerta R2, Quilez AM2, Muriana FJ3, Garcia-Gimenez MD2, Bermudez B4.(PubMed)
(3) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark by Rojas-Duran R1, González-Aspajo G, Ruiz-Martel C, Bourdy G, Doroteo-Ortega VH, Alban-Castillo J, Robert G, Auberger P, Deharo E.(PubMed)
(4) Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report by Tay LY1, Dos Santos FA, Jorge JH.(PubMed)
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