Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotics, etc.
In a total of forty 10-month-old, male Wistar rats received intraperitoneal (IP) injection of CsA (25 mg/kg) for 28 days, the group received garlic (tablets, 400 mg/d) demonstrated reduced LDL levels compared with controls.
Also in patients with Nephrotic syndrome (NS), characterized by proteinuria, oxidative stress and endogenous hyperlipidemia, 2% garlic diet treatment diminished significantly total-cholesterol, LDL-cholesterol and triglycerides, but not HDL-cholesterol, through the attenuation of the rise of lipoperoxidation.
Dr. Bragg DA and Dr. Walling A said," The evidence to support the use of integrative medicine is limited (to the treatment of metabolic syndrome), but the strongest evidence of benefit is for garlic (Allium sativum)".
Furthermore, the Wistar male rats randomly divided into 4 diet groups with garlic supplementation study, also support the effect of garlic in the treatment of hyperlipidemia, as group treated with 200 mg raw garlic/kg body weight, demonstrated the protective effects on HDL in rats with high LDL intake.
In fact, patients with high blood cholesterol may want to add a portion of garlic into their daily diet
but patients with the presence of ulcers should only take garlic or garlic supplement with the permission of herbalists.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) The effect of garlic on cyclosporine-A-induced hyperlipidemia in male rats by Taghizadeh Afshari A1, Shirpoor A, Dodangeh Balakhani E.(PubMed)
(2) Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis by Pedraza-Chaverrí J1, Medina-Campos ON, Granados-Silvestre MA, Maldonado PD, Olivares-Corichi IM, Hernández-Pando R.(PubMed)
(3) Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes by Pedraza-Chaverrí J1, Maldonado PD, Medina-Campos ON, Olivares-Corichi IM, Granados-Silvestre MA, Hernández-Pando R, Ibarra-Rubio ME.(PubMed)
(4) Metabolic Syndrome: Hyperlipidemia by Bragg DA1, Walling A1.(PubMed)
Monday, February 10, 2020
Sunday, February 9, 2020
Herbal Cayenne Adverse Effects on Circulatory System
People who regular Intake of cayenne pepper pills for weight loss should be careful as cayenne pepper pills have shown to induce Myocardial infarction (MI).
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions, used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
According to the Harran University, Capsaicin supplement, one of the major active components of cayenne pepper pills found over the counter substance also induced severe chest pain with an extensive inferior myocardial infarction on a 25 years old male.
In fact, use of capsaicin patch may also cause harm to the circulatory system, Dr. said Akçay AB, the lead researcher said, " A 29-year-old man experienced coronary vasospasm and acute myocardial infarction (AMI) which were possibly induced by the use of a topical capsaicin patch to relieve lumbago" and " the vasospasm and subsequent AMI was attributed to the use of the capsaicin patch for six days".
And ingestion of peppers and chili peppers are found to associate with arterial hypertensive crisis and acute myocardial infarction through the expression of high levels of thyroid-stimulating hormone.
Therefore, people who used any type of cayenne supplement as a topical painkiller, weight loss,.... should consult with special field experts in the prevention of the adverse effect on the circulatory system.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) A case of acute myocardial infarction due to the use of cayenne pepper pills by Sayin MR1, Karabag T, Dogan SM, Akpinar I, Aydin M.(PubMed)
(2) Acute myocardial infarction and coronary vasospasm associated with the ingestion of cayennepepper pills in a 25-year-old male by Sogut O1, Kaya H, Gokdemir MT, Sezen Y.(PubMed)
(3) Coronary vasospasm and acute myocardial infarction induced by a topical capsaicin patch by Akçay AB1, Ozcan T, Seyis S, Acele A.(PubMed)
(4) Capsaicin, arterial hypertensive crisis and acute myocardial infarction associated with high levels of thyroid stimulating hormone by Patanè S, Marte F, Di Bella G, Cerrito M, Coglitore S.(PubMed)
Fennel In Attenuating the Risk, Progression and Treatment of Intestinal Dysbiosis
Fennel may have a potential and therapeutic effect in reduced risk, progression and treatment of gastrointestinal dysbiosis, some scientists suggested.
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil in risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in reduced concentration of the growth of potential pathogens in compared to isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decrease levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180 day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut micro flora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), diet accompanied with 2 mentioned mixed powder plants (0.5% of total diet), diet with TF mixed powder plant and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti antimicrobial activity of gut in comparison to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a function herb for reduced risk, progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP.(PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut micro flora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil in risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in reduced concentration of the growth of potential pathogens in compared to isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decrease levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180 day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut micro flora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), diet accompanied with 2 mentioned mixed powder plants (0.5% of total diet), diet with TF mixed powder plant and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti antimicrobial activity of gut in comparison to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a function herb for reduced risk, progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP.(PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut micro flora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
Cranberry Promotes Postprandial Blood Glucose Management
Postprandial blood glucose is the range of blood glucose that is measured by the blood glucose test, taking after 2 hours of a meal.
At this point of measurement, postprandial blood glucose in a healthy individual usually gone back down. In other words, lower or equal to 7.8 mmol/L (140 mg/dL) 2 hours after eating is normal blood glucose found in a healthy individual.
Glycemic response is a change in blood glucose after consuming carbohydrate-containing food compared to Glycemic Index (GI) that ranks carbohydrate-containing foods, according to their effect on blood glucose levels.
In other words, the glycemic response is the change of blood glucose after the intake of a food or meal.
More precisely, healthy people who are not prediabetes or diabetes have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.
According to the 2015 statistics by the American Diabetes Association, in the U.S. over 30.3 million Americans or 9.4% of the population are living with diabetes. Sadly, out of 30.3 million adults with diabetes, 23.1 million were diagnosed, and 7.2 million were undiagnosed.
In 2015, 84.1 million Americans age 18 and older had prediabetes.
According to the epidemiological studies, by managing postprandial blood glucose effectively, diabetics can decrease the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diabetes, researchers investigated the postprandial effects of dried cranberries following a high-fat breakfast challenge in obese participants with type 2 diabetes (T2DM).
The randomized crossover trial includes blood draw and vascular measurements such as fasting, 1, 2 and 4 hours (h), following the consumption of a fast-food style high-fat breakfast (70 g fat, 974 kcal) with or without cranberries (40 g).
According to the results of the analysis, biomarkers associated with inflammation and oxidative markers such as interleukin-18 and malondialdehyde were significantly lower at 4 h.
Serum total nitrite was found to be higher at 2 h in the cranberry compared to the control group.
However, there were no significant differences in levels of insulin, insulin resistance, lipid profiles and blood pressure between the cranberry and control group.
Furthermore, cranberries showed no effect on the levels of C-reactive protein or interleukin-6.
In other words, dietary cranberries inhibited the high-fat breakfast induced postprandial glucose and selected biomarkers of inflammation and oxidation in patients with T2DM without affecting other parameters associated with diabetes such as insulin, insulin resistance, lipid profiles, and blood pressure.
Based on the findings, researchers said, "adding whole cranberries to a high-fat meal may improve postprandial blood glucose management and warrant further investigation".
Taken altogether, cranberry may be considered a remedy used for the postprandial blood glucose management, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries improve postprandial glucose excursions in type 2 diabetes buSchell J1, Betts NM, Foster M, Scofield RH, Basu A. (PubMed)
(2) Impact of Cranberry Juice Enriched with Omega-3 Fatty Acids Adjunct with Nonsurgical Periodontal Treatment on Metabolic Control and Periodontal Status in Type 2 Patients with Diabetes with Periodontal Disease by Zare Javid A1, Maghsoumi-Norouzabad L1,2,3, Ashrafzadeh E1,2,3, Yousefimanesh HA4, Zakerkish M5, Ahmadi Angali K6, Ravanbakhsh M2, Babaei H. (PubMed)
At this point of measurement, postprandial blood glucose in a healthy individual usually gone back down. In other words, lower or equal to 7.8 mmol/L (140 mg/dL) 2 hours after eating is normal blood glucose found in a healthy individual.
Glycemic response is a change in blood glucose after consuming carbohydrate-containing food compared to Glycemic Index (GI) that ranks carbohydrate-containing foods, according to their effect on blood glucose levels.
In other words, the glycemic response is the change of blood glucose after the intake of a food or meal.
More precisely, healthy people who are not prediabetes or diabetes have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.
According to the 2015 statistics by the American Diabetes Association, in the U.S. over 30.3 million Americans or 9.4% of the population are living with diabetes. Sadly, out of 30.3 million adults with diabetes, 23.1 million were diagnosed, and 7.2 million were undiagnosed.
In 2015, 84.1 million Americans age 18 and older had prediabetes.
According to the epidemiological studies, by managing postprandial blood glucose effectively, diabetics can decrease the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of diabetes, researchers investigated the postprandial effects of dried cranberries following a high-fat breakfast challenge in obese participants with type 2 diabetes (T2DM).
The randomized crossover trial includes blood draw and vascular measurements such as fasting, 1, 2 and 4 hours (h), following the consumption of a fast-food style high-fat breakfast (70 g fat, 974 kcal) with or without cranberries (40 g).
According to the results of the analysis, biomarkers associated with inflammation and oxidative markers such as interleukin-18 and malondialdehyde were significantly lower at 4 h.
Serum total nitrite was found to be higher at 2 h in the cranberry compared to the control group.
However, there were no significant differences in levels of insulin, insulin resistance, lipid profiles and blood pressure between the cranberry and control group.
Furthermore, cranberries showed no effect on the levels of C-reactive protein or interleukin-6.
In other words, dietary cranberries inhibited the high-fat breakfast induced postprandial glucose and selected biomarkers of inflammation and oxidation in patients with T2DM without affecting other parameters associated with diabetes such as insulin, insulin resistance, lipid profiles, and blood pressure.
Based on the findings, researchers said, "adding whole cranberries to a high-fat meal may improve postprandial blood glucose management and warrant further investigation".
Taken altogether, cranberry may be considered a remedy used for the postprandial blood glucose management, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberries improve postprandial glucose excursions in type 2 diabetes buSchell J1, Betts NM, Foster M, Scofield RH, Basu A. (PubMed)
(2) Impact of Cranberry Juice Enriched with Omega-3 Fatty Acids Adjunct with Nonsurgical Periodontal Treatment on Metabolic Control and Periodontal Status in Type 2 Patients with Diabetes with Periodontal Disease by Zare Javid A1, Maghsoumi-Norouzabad L1,2,3, Ashrafzadeh E1,2,3, Yousefimanesh HA4, Zakerkish M5, Ahmadi Angali K6, Ravanbakhsh M2, Babaei H. (PubMed)
Saturday, February 8, 2020
Ginger, the Potential Remedy for the Prevention and Treatment of Atherosclerosis with No Side Effects
Ginger may have a potential and profound effect in blocking the accumulation of plaques on the arterial wall in initiating the risk of atherosclerosis, some scientists suggested.
Atherosclerosis is a medical condition associated with plaque building up in the arteries, leading to the narrowing of the arterial function in the transportation of oxygenated blood to the heart and other blood of the body.
Plaques are substances made up of the accumulated fat, cholesterol, calcium, and other substances found in the blood, including cadmium.
Long-term accumulation of plaque can also cause hardening and stiffing arterial walls can lead to the blockage of the arteries and risk of heart disease depending on the location of the blockage.
Most people in the early stage of atherosclerosis do not experience any symptoms. However, as the condition progresses and the location affected, patients may develop chest pain, shortness of breath, sweating, and anxiety.
The most common causes of atherosclerosis are the imbalance of the ratio of bad cholesterol and good cholesterol in the blood, long-term smoking, obesity, an increase in age, obesity and some medical conditions, such as diabetes and high blood pressure.
Therefore adding a portion of olive oil into your daily diet can reduce the risk of high blood cholesterol
Dr. Siasos G, the lead scientists in the heart disease team in the concerns of the smoking detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease said, " smoking is an important modifiable risk factor for the development of cardiovascular disease,....via initiation and progression of atherosclerosis".
And, "A variety of studies has proved that cigarette smoking induces oxidative stress, vascular inflammation, platelet coagulation, vascular dysfunction and impairs serum lipid profile in both current and chronic smokers, active and passive smokers and results in detrimental effects on the cardiovascular system".
The statement clearly indicated that cigarette smoking has a strong implication of the onset and progression of atherosclerosis.
Some researchers suggested that cigarette smoke contain a high amount of toxic chemicals that cause inflammation and formation of a blood clot in the arteries and oxidation of low-density lipoprotein cholesterol.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
On finding a natural ingredient or whole food for the prevention and treatment, researchers at the joint study led by the University of Sistan and Baluchestan examined the potential protective effects of ginger in atherosclerosis and atherosclerotic cardiovascular disease.
The randomized, experimental, and controlled study included thirty healthy overweight women aged 20-30 years randomly divided into three equal groups, namely, ginger, ginger + high-intensity interval training (HIIT), and placebo + HIIT.
The training groups performed high-intensity interval exercises (i.e. 40-m maximal shuttle run) for ten consecutive weeks. The supplement groups daily took 3 g of ginger pills and the third group took the placebo.
The paired t-test revealed a significant decrease in the density of type 1 monocytes chemotactic protein (MCP-1) in HIIT + ginger (P = 0.026) and HIIT + placebo (P = 0.001) groups, an indication of reduced inflammation.
These results suggested that the relative and efficient role of HIIT combined with the ginger supplement in overweight women in inducing antioxidant/anti-inflammatory activity against atherosclerosis.
Furthermore, the investigation of the effects of air-dried ginger powder (0.1g/kg body weight, po, for 75 days) was carried out by the RNT Medical College, on experimentally induced atherosclerosis in rabbits by cholesterol feeding (0.3g/kg body weight, po).
Before the administration of ginger powder, cholesterol feeding for 75 days led to the distinct development of atheroma in the aorta and coronary arteries of the rabbits.
The accumulation of plaque in the arteries was significantly inhibited by about 50% following ginger administration.
Moreover, the ginger treatment also decreases lipid peroxidation and enhanced fibrinolytic activity associated to dissolve blood clots.
The findings indicated that ginger distinct protection from the development of atherosclerosis is attributed probably because of its free radical scavengings, prostaglandin inhibitory and fibri
properties.
Taken altogether, ginger may be considered a functional food for the prevention and adjunct therapy for the treatment of atherosclerosis without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Spices and Atherosclerosis by Tsui PF1,2, Lin CS3, Ho LJ4, Lai JH. (PubMed)
(2) The effect of a 10-week high-intensity interval training and ginger consumption on inflammatory indices contributing to atherosclerosis in overweight women by Nayebifar S1, Afzalpour ME2, Kazemi T3, Eivary SH4, Mogharnasi M2. (PubMed)
(3) Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits by Verma SK1, Singh M, Jain P, Bordia A.(PubMed)
(4) Smoking and atherosclerosis: mechanisms of disease and new therapeutic approaches by Siasos G, Tsigkou V, Kokkou E, Oikonomou E, Vavuranakis M, Vlachopoulos C, Verveniotis A, Limperi M, Genimata V, Papavassiliou AG, Stefanadis C, Tousoulis D. (PubMed)
Atherosclerosis is a medical condition associated with plaque building up in the arteries, leading to the narrowing of the arterial function in the transportation of oxygenated blood to the heart and other blood of the body.
Plaques are substances made up of the accumulated fat, cholesterol, calcium, and other substances found in the blood, including cadmium.
Long-term accumulation of plaque can also cause hardening and stiffing arterial walls can lead to the blockage of the arteries and risk of heart disease depending on the location of the blockage.
Most people in the early stage of atherosclerosis do not experience any symptoms. However, as the condition progresses and the location affected, patients may develop chest pain, shortness of breath, sweating, and anxiety.
The most common causes of atherosclerosis are the imbalance of the ratio of bad cholesterol and good cholesterol in the blood, long-term smoking, obesity, an increase in age, obesity and some medical conditions, such as diabetes and high blood pressure.
Therefore adding a portion of olive oil into your daily diet can reduce the risk of high blood cholesterol
Dr. Siasos G, the lead scientists in the heart disease team in the concerns of the smoking detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease said, " smoking is an important modifiable risk factor for the development of cardiovascular disease,....via initiation and progression of atherosclerosis".
And, "A variety of studies has proved that cigarette smoking induces oxidative stress, vascular inflammation, platelet coagulation, vascular dysfunction and impairs serum lipid profile in both current and chronic smokers, active and passive smokers and results in detrimental effects on the cardiovascular system".
The statement clearly indicated that cigarette smoking has a strong implication of the onset and progression of atherosclerosis.
Some researchers suggested that cigarette smoke contain a high amount of toxic chemicals that cause inflammation and formation of a blood clot in the arteries and oxidation of low-density lipoprotein cholesterol.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
On finding a natural ingredient or whole food for the prevention and treatment, researchers at the joint study led by the University of Sistan and Baluchestan examined the potential protective effects of ginger in atherosclerosis and atherosclerotic cardiovascular disease.
The randomized, experimental, and controlled study included thirty healthy overweight women aged 20-30 years randomly divided into three equal groups, namely, ginger, ginger + high-intensity interval training (HIIT), and placebo + HIIT.
The training groups performed high-intensity interval exercises (i.e. 40-m maximal shuttle run) for ten consecutive weeks. The supplement groups daily took 3 g of ginger pills and the third group took the placebo.
The paired t-test revealed a significant decrease in the density of type 1 monocytes chemotactic protein (MCP-1) in HIIT + ginger (P = 0.026) and HIIT + placebo (P = 0.001) groups, an indication of reduced inflammation.
These results suggested that the relative and efficient role of HIIT combined with the ginger supplement in overweight women in inducing antioxidant/anti-inflammatory activity against atherosclerosis.
Furthermore, the investigation of the effects of air-dried ginger powder (0.1g/kg body weight, po, for 75 days) was carried out by the RNT Medical College, on experimentally induced atherosclerosis in rabbits by cholesterol feeding (0.3g/kg body weight, po).
Before the administration of ginger powder, cholesterol feeding for 75 days led to the distinct development of atheroma in the aorta and coronary arteries of the rabbits.
The accumulation of plaque in the arteries was significantly inhibited by about 50% following ginger administration.
Moreover, the ginger treatment also decreases lipid peroxidation and enhanced fibrinolytic activity associated to dissolve blood clots.
The findings indicated that ginger distinct protection from the development of atherosclerosis is attributed probably because of its free radical scavengings, prostaglandin inhibitory and fibri
properties.
Taken altogether, ginger may be considered a functional food for the prevention and adjunct therapy for the treatment of atherosclerosis without inducing any adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Spices and Atherosclerosis by Tsui PF1,2, Lin CS3, Ho LJ4, Lai JH. (PubMed)
(2) The effect of a 10-week high-intensity interval training and ginger consumption on inflammatory indices contributing to atherosclerosis in overweight women by Nayebifar S1, Afzalpour ME2, Kazemi T3, Eivary SH4, Mogharnasi M2. (PubMed)
(3) Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits by Verma SK1, Singh M, Jain P, Bordia A.(PubMed)
(4) Smoking and atherosclerosis: mechanisms of disease and new therapeutic approaches by Siasos G, Tsigkou V, Kokkou E, Oikonomou E, Vavuranakis M, Vlachopoulos C, Verveniotis A, Limperi M, Genimata V, Papavassiliou AG, Stefanadis C, Tousoulis D. (PubMed)
Herbal Bilberry In the Prevention and Treatment of Cardiovascular Disease (CVD
Cardiovascular disease is a general term of diseases associated with the blood vessels and heart, including coronary artery diseases (CAD) affected by obstruction of arteries and stroke-affected by the capillaries in the brain.
In other words, the disease in CVD is vary depending on the affected locations. Atherosclerosis is also the most common cause of cardiovascular disease.
The exact causes of CVD are not clear. However, high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, are found to associated with the increased risk of CVD.
According to the statistics provided by the American Heart Association, over 84 million people in the US suffer from some forms of cardiovascular disease, causing the death of 2,200 people a day.
Sadly, approximately 15 million U.S. adults have coronary heart disease.
Out of many risk factors, some researchers suggested that high blood pressure found in 103 million U.S. adults are one of the major cause of CVD. Believe it or not, approximately 54% of strokes and 47% of coronary heart diseases, worldwide, are attributable to high blood pressure.
Dr. Chen-Yi Wu, the lead scientist said, "The cardiovascular and expanded-cardiovascular mortality risks were lowest when systolic blood pressures were 120 to 129 mm Hg, and increased significantly when systolic blood pressures (SBPs) were ≥160 mm Hg or diastolic BPs were ≥90 mm Hg".
And, " The impacts of stage 2–3 hypertension on mortality risks were significantly increased among women. The mortality risks of hypertension were not attenuated with older age".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer,
In the urgency to find a natural ingredient for the prevention of cardiovascular diseases (CVD), a leading cause of death researchers examined the bilberry's beneficial effects on CVD risk reduction.
The study included women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks.
According to the tested assays, consumption of bilberries showed a decrease of total cholesterol, LDL-C, TG, glucose, albumin, γ-glutamyltransferase, and a positive increase in HDL-C.
All parameters associated with the risk of CVD were decreased substantially at the end of the study. In other words, bilberry reduced the risk of CVD by promoting the blood flow to the heart and other parts of the body.
Interestingly, in men, favorable changes were observed in total cholesterol, glucose, albumin, aspartate aminotransferase, γ-glutamyltransferase, and HDL-C compared to women.
The results strongly support the regular use of bilberries as a dietary source of fruit to reduce the CVDs risk, by decreasing LDL-C/TG and increasing HDL-C.
Dr. Habanova M, after taking into account co and confound wrote in the final report, "Changes in other parameters were not significant, for both women and men. Thus, the regular intake of bilberries can be important to reduce CVDs risk, by decreasing LDL-C/TG and increasing HDL-C".
Taken altogether, bilberry may be considered a functioning remedy for the prevention of cardiovascular diseases (CVD), pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovasculardisease by inducing favorable changes in lipoprotein profiles by Habanova M1, Saraiva JA2, Haban M3, Schwarzova M4, Chlebo P5, Predna L6, Gažo J7, Wyka J. (PubMed)
(2) A Brief Review of Blue- and Bilberries' Potential to Curb Cardio-Metabolic Perturbations: Focus on Diabetes by Crespo MC1, Visioli F. (PubMed)
(3) High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults by Chen-Yi Wu, MD, PhD, Hsiao-Yun Hu, PhD, Yiing-Jenq Chou, MD, PhD, Nicole Huang, PhD, Yi-Chang Chou, MS, and Chung-Pin Li, MD, PhD. (PMC)
In other words, the disease in CVD is vary depending on the affected locations. Atherosclerosis is also the most common cause of cardiovascular disease.
The exact causes of CVD are not clear. However, high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, are found to associated with the increased risk of CVD.
According to the statistics provided by the American Heart Association, over 84 million people in the US suffer from some forms of cardiovascular disease, causing the death of 2,200 people a day.
Sadly, approximately 15 million U.S. adults have coronary heart disease.
Out of many risk factors, some researchers suggested that high blood pressure found in 103 million U.S. adults are one of the major cause of CVD. Believe it or not, approximately 54% of strokes and 47% of coronary heart diseases, worldwide, are attributable to high blood pressure.
Dr. Chen-Yi Wu, the lead scientist said, "The cardiovascular and expanded-cardiovascular mortality risks were lowest when systolic blood pressures were 120 to 129 mm Hg, and increased significantly when systolic blood pressures (SBPs) were ≥160 mm Hg or diastolic BPs were ≥90 mm Hg".
And, " The impacts of stage 2–3 hypertension on mortality risks were significantly increased among women. The mortality risks of hypertension were not attenuated with older age".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer,
In the urgency to find a natural ingredient for the prevention of cardiovascular diseases (CVD), a leading cause of death researchers examined the bilberry's beneficial effects on CVD risk reduction.
The study included women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks.
According to the tested assays, consumption of bilberries showed a decrease of total cholesterol, LDL-C, TG, glucose, albumin, γ-glutamyltransferase, and a positive increase in HDL-C.
All parameters associated with the risk of CVD were decreased substantially at the end of the study. In other words, bilberry reduced the risk of CVD by promoting the blood flow to the heart and other parts of the body.
Interestingly, in men, favorable changes were observed in total cholesterol, glucose, albumin, aspartate aminotransferase, γ-glutamyltransferase, and HDL-C compared to women.
The results strongly support the regular use of bilberries as a dietary source of fruit to reduce the CVDs risk, by decreasing LDL-C/TG and increasing HDL-C.
Dr. Habanova M, after taking into account co and confound wrote in the final report, "Changes in other parameters were not significant, for both women and men. Thus, the regular intake of bilberries can be important to reduce CVDs risk, by decreasing LDL-C/TG and increasing HDL-C".
Taken altogether, bilberry may be considered a functioning remedy for the prevention of cardiovascular diseases (CVD), pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovasculardisease by inducing favorable changes in lipoprotein profiles by Habanova M1, Saraiva JA2, Haban M3, Schwarzova M4, Chlebo P5, Predna L6, Gažo J7, Wyka J. (PubMed)
(2) A Brief Review of Blue- and Bilberries' Potential to Curb Cardio-Metabolic Perturbations: Focus on Diabetes by Crespo MC1, Visioli F. (PubMed)
(3) High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults by Chen-Yi Wu, MD, PhD, Hsiao-Yun Hu, PhD, Yiing-Jenq Chou, MD, PhD, Nicole Huang, PhD, Yi-Chang Chou, MS, and Chung-Pin Li, MD, PhD. (PMC)
Herbal Anise In the Expression of Depressant-like Activity
Anise may have a potential and substantial effect in reduced risk and treatment of depression, some scientists suggested.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic,...
Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
Depression is a condition of a mood disorder. affecting the patient's feelings, think, and handle daily activities.
According to the statistic of The National Institute of Mental Health, approximately, 16 million adults had at least one major depressive episode in 2012 in the United States, 6.9 percent of the population.
In the evaluation of the herbal Anise aqueous and ethanol extracts antidepressant-like effect in mice with several different doses of 50, 100 and 200 mg/kg in compared to the standard medicine Fluoxetine at dose of 30mg/kg and imipramine at dose of 20mg/kg, researchers at the joint study lead by the Azad University showed that except for the dose at 50mg/kg of aqueous extract, application of other doses demonstrated a linearly significant improvement of mobility times.
Further analysis also found that all doses from Anise extract increased the swimming time dose-dependently, without any significant change in climbing time in tested mice similar to those of Fluoxetine and compared to aqueous extract.
Moreover, Fluoxetine and imipramine expressed a strong decreased immobility time in both tests in contrast to imipramine increased climbing time without any significant change in swimming time.
The result suggested that both extracts in a dose higher than 50mg/kg display antidepressant-like activity similar to that of fluoxetine through improved mobility of depressed mice as inactivity is considered as one of the major symptoms in patients with depression.
As the depression progressed, patients demonstrated behavior in making efforts to escape from society, eventually will exhibit immobility with the reflection of psychological despair.
Dr. Shahamat Z the lead author said, " P. anisum possesses an antidepressant-like activity similar to that of fluoxetine, which has a potential clinical value for application in the management of depression".
Additionally, in the testing essential (volatile) oil and essential oil of Piper laetispicum antidepressant activity in compared to Fluoxetine as standard antidepressant drug and other natural remedies including Leaves-Bay, Curry, Coriander and Mint; Fruits-Star anise, Pepper, Cardamom, Caraway and Fennel; Seeds of Fenugreek, Mustard, Nutmeg and Black Cumin; and Underground stem-Onion, Garlic, Ginger and Turmeric; Miscellaneous-Clove, Cinnamon, Capsicum, Tamarind and Asafoetida, researchers found that all participated essential oil, especially anise produced a significant reduction in immobility along with an increase in climbing behavior similar to those of fluoxetine.
The application of essential oil caused a dose-dependent reduction( probably in a dose less than 50 mg/kg) in immobility which is contracted to the above study and an increase in climbing at all studied doses in comparison to the control group.
However, the test may not take into effect in real-life patients who need to be treated for at least several weeks before they experience any relief from the expression of symptoms.
Furthermore, in the examine of the efficacy of anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome of a total of 120 randomly assigned into 3 equal groups received anise oil, Colpermin, and placebo, at the end of the study, scientists showed that application of anise group exerted a continuous improvement of the syndrome in compared to the other 2 groups with some unknown mechanisms.
Some researchers postulated that essential oil smell may have a profound effect on the brain in triggering an emotional reaction in stimulating the limbic system in regulated autonomic and endocrine function, particularly, in response to emotional stimuli in an expression of motivation and reinforcing behaviors.
Additionally, the application of essential oil scent also has a direct influence in calming the central nervous system in ameliorated overproduction of certain hormones in reacted to unfavorably emotional behaviors.
Taken together, Anise essential oil may be used as a secondary therapy to standard medicine in the treatment of depression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Evaluation of antidepressant-like effects of aqueous and ethanolic extracts of Pimpinella anisum fruit in mice by Shahamat Z1, Abbasi-Maleki S2, Mohammadi Motamed S3.(PubMed)
(2) Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome. A Randomized Active and Placebo-Controlled Clinical Trial by Maryam Mosaffa-Jahromi, PharmD, PhD, Ali-Mohammad Tamaddon, PharmD, PhD, Suleiman Afsharypuor, PharmD, PhD, Alireza Salehi, MD, MPH, PhD, Seyed Hassan Seradj, PharmD, PhD, Mehdi Pasalar MD, MPH, PhD, Peyman Jafari, PhD, Kamran Bagheri Lankarani, MD (Journal of Evidence-Based Integrative Medicine)
(3) Essential oil isolation from culinary drugs and screening for antidepressant potential Mohib Abdul Jalil Khan , Imtiyaz Ansari, Amjad Ali Mohammad Iqbal Oriental College of Pharmacy, Navi Mumbai, Maharashtra- 400705, India.(INTERNATIONAL JOURNAL OF ADVANCES INPHARMACY MEDICINE AND BIOALLIED SCIENCES)
(4) The Forced Swim Test as a Model of Depressive-like Behavior by Roni Yankelevitch-Yahav, 1 , 2 Motty Franko, 2 Avrham Huly, 2 and Ravid Doron(PMC)
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic,...
Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
Depression is a condition of a mood disorder. affecting the patient's feelings, think, and handle daily activities.
According to the statistic of The National Institute of Mental Health, approximately, 16 million adults had at least one major depressive episode in 2012 in the United States, 6.9 percent of the population.
In the evaluation of the herbal Anise aqueous and ethanol extracts antidepressant-like effect in mice with several different doses of 50, 100 and 200 mg/kg in compared to the standard medicine Fluoxetine at dose of 30mg/kg and imipramine at dose of 20mg/kg, researchers at the joint study lead by the Azad University showed that except for the dose at 50mg/kg of aqueous extract, application of other doses demonstrated a linearly significant improvement of mobility times.
Further analysis also found that all doses from Anise extract increased the swimming time dose-dependently, without any significant change in climbing time in tested mice similar to those of Fluoxetine and compared to aqueous extract.
Moreover, Fluoxetine and imipramine expressed a strong decreased immobility time in both tests in contrast to imipramine increased climbing time without any significant change in swimming time.
The result suggested that both extracts in a dose higher than 50mg/kg display antidepressant-like activity similar to that of fluoxetine through improved mobility of depressed mice as inactivity is considered as one of the major symptoms in patients with depression.
As the depression progressed, patients demonstrated behavior in making efforts to escape from society, eventually will exhibit immobility with the reflection of psychological despair.
Dr. Shahamat Z the lead author said, " P. anisum possesses an antidepressant-like activity similar to that of fluoxetine, which has a potential clinical value for application in the management of depression".
Additionally, in the testing essential (volatile) oil and essential oil of Piper laetispicum antidepressant activity in compared to Fluoxetine as standard antidepressant drug and other natural remedies including Leaves-Bay, Curry, Coriander and Mint; Fruits-Star anise, Pepper, Cardamom, Caraway and Fennel; Seeds of Fenugreek, Mustard, Nutmeg and Black Cumin; and Underground stem-Onion, Garlic, Ginger and Turmeric; Miscellaneous-Clove, Cinnamon, Capsicum, Tamarind and Asafoetida, researchers found that all participated essential oil, especially anise produced a significant reduction in immobility along with an increase in climbing behavior similar to those of fluoxetine.
The application of essential oil caused a dose-dependent reduction( probably in a dose less than 50 mg/kg) in immobility which is contracted to the above study and an increase in climbing at all studied doses in comparison to the control group.
However, the test may not take into effect in real-life patients who need to be treated for at least several weeks before they experience any relief from the expression of symptoms.
Furthermore, in the examine of the efficacy of anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome of a total of 120 randomly assigned into 3 equal groups received anise oil, Colpermin, and placebo, at the end of the study, scientists showed that application of anise group exerted a continuous improvement of the syndrome in compared to the other 2 groups with some unknown mechanisms.
Some researchers postulated that essential oil smell may have a profound effect on the brain in triggering an emotional reaction in stimulating the limbic system in regulated autonomic and endocrine function, particularly, in response to emotional stimuli in an expression of motivation and reinforcing behaviors.
Additionally, the application of essential oil scent also has a direct influence in calming the central nervous system in ameliorated overproduction of certain hormones in reacted to unfavorably emotional behaviors.
Taken together, Anise essential oil may be used as a secondary therapy to standard medicine in the treatment of depression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Evaluation of antidepressant-like effects of aqueous and ethanolic extracts of Pimpinella anisum fruit in mice by Shahamat Z1, Abbasi-Maleki S2, Mohammadi Motamed S3.(PubMed)
(2) Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome. A Randomized Active and Placebo-Controlled Clinical Trial by Maryam Mosaffa-Jahromi, PharmD, PhD, Ali-Mohammad Tamaddon, PharmD, PhD, Suleiman Afsharypuor, PharmD, PhD, Alireza Salehi, MD, MPH, PhD, Seyed Hassan Seradj, PharmD, PhD, Mehdi Pasalar MD, MPH, PhD, Peyman Jafari, PhD, Kamran Bagheri Lankarani, MD (Journal of Evidence-Based Integrative Medicine)
(3) Essential oil isolation from culinary drugs and screening for antidepressant potential Mohib Abdul Jalil Khan , Imtiyaz Ansari, Amjad Ali Mohammad Iqbal Oriental College of Pharmacy, Navi Mumbai, Maharashtra- 400705, India.(INTERNATIONAL JOURNAL OF ADVANCES INPHARMACY MEDICINE AND BIOALLIED SCIENCES)
(4) The Forced Swim Test as a Model of Depressive-like Behavior by Roni Yankelevitch-Yahav, 1 , 2 Motty Franko, 2 Avrham Huly, 2 and Ravid Doron(PMC)
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